miRTarBase - #MIRT500154


—
pre-miRNA Information
pre-miRNA hsa-mir-1245a   
Genomic Coordinates chr2: 188978092 - 188978161
Description Homo sapiens miR-1245a stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-1245a
Sequence 45| AAGUGAUCUAAAGGCCUACAU |65
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31562560 15 COSMIC
COSN26581044 19 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs906938680 2 dbSNP
rs1159117523 3 dbSNP
rs780486044 6 dbSNP
rs771479866 17 dbSNP
rs1002976932 18 dbSNP
rs1428029219 19 dbSNP
Putative Targets

Gene Information
Gene Symbol CREBBP   
Synonyms CBP, KAT3A, RSTS, RSTS1
Description CREB binding protein
Transcript NM_001079846   
Other Transcripts NM_004380   
Expression
Putative miRNA Targets on CREBBP
3'UTR of CREBBP
(miRNA target sites are highlighted)		 
>CREBBP|NM_001079846|3'UTR
   1 CATTGTGAGAGCATCACCTTTTCCCTTTCATGTTCTTGGACCTTTTGTACTGAAAATCCAGGCATCTAGGTTCTTTTTAT
  81 TCCTAGATGGAACTGCGACTTCCGAGCCATGGAAGGGTGGATTGATGTTTAAAGAAACAATACAAAGAATATATTTTTTT
 161 GTTAAAAACCAGTTGATTTAAATATCTGGTCTCTCTCTTTGGTTTTTTTTTGGCGGGGGGGTGGGGGGGGTTCTTTTTTT
 241 TCCGTTTTGTTTTTGTTTGGGGGGAGGGGGGTTTTGTTTGGATTCTTTTTGTCGTCATTGCTGGTGACTCATGCCTTTTT
 321 TTAACGGGAAAAACAAGTTCATTATATTCATATTTTTTATTTGTATTTTCAAGACTTTAAACATTTATGTTTAAAAGTAA
 401 GAAGAAAAATAATATTCAGAACTGATTCCTGAAATAATGCAAGCTTATAATGTATCCCGATAACTTTGTGATGTTTCGGG
 481 AAGATTTTTTTCTATAGTGAACTCTGTGGGCGTCTCCCAGTATTACCCTGGATGATAGGAATTGACTCCGGCGTGCACAC
 561 ACGTACACACCCACACACATCTATCTATACATAATGGCTGAAGCCAAACTTGTCTTGCAGATGTAGAAATTGTTGCTTTG
 641 TTTCTCTGATAAAACTGGTTTTAGACAAAAAATAGGGATGATCACTCTTAGACCATGCTAATGTTACTAGAGAAGAAGCC
 721 TTCTTTTCTTTCTTCTATGTGAAACTTGAAATGAGGAAAAGCAATTCTAGTGTAAATCATGCAAGCGCTCTAATTCCTAT
 801 AAATACGAAACTCGAGAAGATTCAATCACTGTATAGAATGGTAAAATACCAACTCATTTCTTATATCATATTGTTAAATA
 881 AACTGTGTGCAACAGACAAAAAGGGTGGTCCTTCTTGAATTCATGTACATGGTATTAACACTTAGTGTTCGGGGTTTTTT
 961 GTTATGAAAATGCTGTTTTCAACATTGTATTTGGACTATGCATGTGTTTTTTCCCCATTGTATATAAAGTACCGCTTAAA
1041 ATTGATATAAATTACTGAGGTTTTTAACATGTATTCTGTTCTTTAAGATCCCTGTAAGAATGTTTAAGGTTTTTATTTAT
1121 TTATATATATTTTTTGAGTCTGTTCTTTGTAAGACATGGTTCTGGTTGTTCGCTCATAGCGGAGAGGCTGGGGCTGCGGT
1201 TGTGGTTGTGGCGGCGTGGGTGGTGGCTGGGAACTGTGGCCCAGGCTTAGCGGCCGCCCGGAGGCTTTTCTTCCCGGAGA
1281 CTGAGGTGGGCGACTGAGGTGGGCGGCTCAGCGTTGGCCCCACACATTCGAGGCTCACAGGTGATTGTCGCTCACACAGT
1361 TAGGGTCGTCAGTTGGTCTGAAACTGCATTTGGCCCACTCCTCCATCCTCCCTGTCCGTCGTAGCTGCCACCCCCAGAGG
1441 CGGCGCTTCTTCCCGTGTTCAGGCGGCTCCCCCCCCCCGTACACGACTCCCAGAATCTGAGGCAGAGAGTGCTCCAGGCT
1521 CGCGAGGTGCTTTCTGACTTCCCCCCAAATCCTGCCGCTGCCGCGCAGCATGTCCCGTGTGGCGTTTGAGGAAATGCTGA
1601 GGGACAGACACCTTGGAGCACCAGCTCCGGTCCCTGTTACAGTGAGAAAGGTCCCCCACTTCGGGGGATACTTGCACTTA
1681 GCCACATGGTCCTGCCTCCCTTGGAGTCCAGTTCCAGGCTCCCTTACTGAGTGGGTGAGACAAGTTCACAAAAACCGTAA
1761 AACTGAGAGGAGGACCATGGGCAGGGGAGCTGAAGTTCATCCCCTAAGTCTACCACCCCCAGCACCCAGAGAACCCACTT
1841 TATCCCTAGTCCCCCAACAAAGGCTGGTCTAGGTGGGGGTGATGGTAATTTTAGAAATCACGCCCCAAATAGCTTCCGTT
1921 TGGGCCCTTACATTCACAGATAGGTTTTAAATAGCTGAATACTTGGTTTGGGAATCTGAATTCGAGGAACCTTTCTAAGA
2001 AGTTGGAAAGGTCCGATCTAGTTTTAGCACAGAGCTTTGAACCTTGAGTTATAAAATGCAGAATAATTCAAGTAAAAATA
2081 AGACCACCATCTGGCACCCCTGACCAGCCCCCATTCACCCCATCCCAGGAGGGGAAGCACAGGCCGGGCCTCCGGTGGAG
2161 ATTGCTGCCACTGCTCGGCCTGCTGGGTTCTTAACCTCCAGTGTCCTCTTCATCTTTTCCACCCGTAGGGAAACCTTGAG
2241 CCATGTGTTCAAACAAGAAGTGGGGCTAGAGCCCGAGAGCAGCAGCTCTAAGCCCACACTCAGAAAGTGGCGCCCTCCTG
2321 GTTGTGCAGCCTTTTAATGTGGGCAGTGGAGGGGCCTCTGTTTCAGGTTATCCTGGAATTCAAAACGTTATGTACCAACC
2401 TCATCCTCTTTGGAGTCTGCATCCTGTGCAACCGTCTTGGGCAATCCAGATGTCGAAGGATGTGACCGAGAGCATGGTCT
2481 GTGGATGCTAACCCTAAGTTTGTCGTAAGGAAATTTCTGTAAGAAACCTGGAAAGCCCCAACGCTGTGTCTCATGCTGTA
2561 TACTTAAGAGGAGAAGAAAAAGTCCTATATTTGTGATCAAAAAGAGGAAACTTGAAATGTGATGGTGTTTATAATAAAAG
2641 ATGGTAAAACTACTTGGATTCAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' uacAUCCGGAAAUCUAGUGAa 5'
             ||||  |   ||||||| 
Target 5' aaaTAGGGAT---GATCACTc 3'
 670 - 687 147.00 -10.40
2 
miRNA  3' uaCAU----CCGGAAA-UCUAGUGAa 5'
            |||    | :|||| ||||| || 
Target 5' atGTATTCTGTTCTTTAAGATCCCTg 3'
 1069 - 1094 129.00 -8.30
3 
miRNA  3' uacaUCCGGA----A-AUCUAGUGAa 5'
              :|||||    |  ||||::|| 
Target 5' ggccGGGCCTCCGGTGGAGATTGCTg 3'
 2142 - 2167 119.00 -11.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
522462 247 ClinVar
COSN30487120 24 COSMIC
COSN30121764 35 COSMIC
COSN30130322 103 COSMIC
COSN31491915 143 COSMIC
COSN18739298 154 COSMIC
COSN31769317 202 COSMIC
COSN29211817 434 COSMIC
COSN31546876 465 COSMIC
COSN31482040 511 COSMIC
COSN26584349 562 COSMIC
COSN26568294 571 COSMIC
COSN31769938 917 COSMIC
COSN1698406 998 COSMIC
COSN31579687 1012 COSMIC
COSN31484069 1044 COSMIC
COSN8499610 1107 COSMIC
COSN31610385 1172 COSMIC
COSN31518210 1192 COSMIC
COSN20112561 1279 COSMIC
COSN27591735 1469 COSMIC
COSN31769937 1711 COSMIC
COSN32063820 1938 COSMIC
COSN17075825 2312 COSMIC
COSN31584755 2576 COSMIC
COSN26868700 2606 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1007567958 7 dbSNP
rs780837684 10 dbSNP
rs1386623585 11 dbSNP
rs755034771 12 dbSNP
rs751483136 16 dbSNP
rs763197100 17 dbSNP
rs1333924375 18 dbSNP
rs2230140 22 dbSNP
rs199553418 23 dbSNP
rs201047390 26 dbSNP
rs201851173 26 dbSNP
rs1171710566 27 dbSNP
rs568317336 28 dbSNP
rs142721165 29 dbSNP
rs774602465 29 dbSNP
rs923792953 29 dbSNP
rs1345384993 30 dbSNP
rs554483949 32 dbSNP
rs761355594 36 dbSNP
rs1304261477 37 dbSNP
rs753170365 41 dbSNP
rs767800871 42 dbSNP
rs917680914 43 dbSNP
rs1185125180 44 dbSNP
rs760052559 48 dbSNP
rs774794414 51 dbSNP
rs1276841574 58 dbSNP
rs1442765003 63 dbSNP
rs922142096 64 dbSNP
rs147393693 68 dbSNP
rs1244418439 69 dbSNP
rs1374340432 72 dbSNP
rs1319768263 76 dbSNP
rs565641940 82 dbSNP
rs1440221736 83 dbSNP
rs908871433 85 dbSNP
rs777625262 96 dbSNP
rs950988032 98 dbSNP
rs758118196 99 dbSNP
rs912011429 103 dbSNP
rs142933739 104 dbSNP
rs1017728739 106 dbSNP
rs1177485080 108 dbSNP
rs866778193 109 dbSNP
rs1404391128 110 dbSNP
rs1412837512 112 dbSNP
rs1159117730 120 dbSNP
rs950805385 147 dbSNP
rs1336264921 148 dbSNP
rs1007639963 149 dbSNP
rs1422563275 161 dbSNP
rs893170111 161 dbSNP
rs1349696639 163 dbSNP
rs1223691766 169 dbSNP
rs1028080461 181 dbSNP
rs1342182148 182 dbSNP
rs1454959115 186 dbSNP
rs1199405465 188 dbSNP
rs1273168050 189 dbSNP
rs1207973518 193 dbSNP
rs1250038622 194 dbSNP
rs973392641 197 dbSNP
rs1042661759 199 dbSNP
rs1200321570 199 dbSNP
rs969951187 199 dbSNP
rs998832657 199 dbSNP
rs1397347582 201 dbSNP
rs1431523077 203 dbSNP
rs1306127696 206 dbSNP
rs1187212665 210 dbSNP
rs1466691766 211 dbSNP
rs1302885938 212 dbSNP
rs949249041 212 dbSNP
rs1243204280 214 dbSNP
rs1340926528 215 dbSNP
rs1174132463 217 dbSNP
rs1273112006 220 dbSNP
rs1209436180 221 dbSNP
rs1223670587 222 dbSNP
rs1450048543 222 dbSNP
rs976178119 222 dbSNP
rs532228107 223 dbSNP
rs1280949298 227 dbSNP
rs1166569294 229 dbSNP
rs1425288765 230 dbSNP
rs1295066189 231 dbSNP
rs1366655656 231 dbSNP
rs1388358843 231 dbSNP
rs966093068 231 dbSNP
rs1235346500 233 dbSNP
rs1296307791 236 dbSNP
rs1209422543 242 dbSNP
rs1246216543 242 dbSNP
rs1267578026 242 dbSNP
rs1342067297 242 dbSNP
rs1354711236 242 dbSNP
rs1348294215 243 dbSNP
rs1296667743 244 dbSNP
rs1226075054 249 dbSNP
rs1445136660 252 dbSNP
rs1363922020 254 dbSNP
rs1166889865 255 dbSNP
rs368559038 255 dbSNP
rs1289399736 258 dbSNP
rs896305093 260 dbSNP
rs1390365359 261 dbSNP
rs1432534282 262 dbSNP
rs1356974652 263 dbSNP
rs1382941769 264 dbSNP
rs1017589253 265 dbSNP
rs1397069729 265 dbSNP
rs1244535926 269 dbSNP
rs1054832232 271 dbSNP
rs1207104783 272 dbSNP
rs1267561260 276 dbSNP
rs937745745 277 dbSNP
rs1183488755 279 dbSNP
rs1254010564 281 dbSNP
rs1423230801 281 dbSNP
rs1182252650 286 dbSNP
rs567905024 288 dbSNP
rs867343107 289 dbSNP
rs569491710 293 dbSNP
rs1167029812 294 dbSNP
rs1014074793 298 dbSNP
rs908944533 300 dbSNP
rs549775416 304 dbSNP
rs376952863 312 dbSNP
rs1467134201 316 dbSNP
rs1305052630 317 dbSNP
rs928930858 323 dbSNP
rs530340770 325 dbSNP
rs999024790 326 dbSNP
rs904238799 343 dbSNP
rs1352767565 350 dbSNP
rs1226748613 358 dbSNP
rs966271963 362 dbSNP
rs1482298527 363 dbSNP
rs752407316 363 dbSNP
rs1017771792 365 dbSNP
rs1043117934 370 dbSNP
rs932304953 378 dbSNP
rs986236576 379 dbSNP
rs957460016 382 dbSNP
rs1033065558 384 dbSNP
rs998862254 389 dbSNP
rs1482867796 401 dbSNP
rs1205843649 403 dbSNP
rs1253638241 404 dbSNP
rs1482888452 407 dbSNP
rs1180917461 410 dbSNP
rs1429567975 415 dbSNP
rs900792095 424 dbSNP
rs1173342084 428 dbSNP
rs1358116946 429 dbSNP
rs1039291624 432 dbSNP
rs903141676 443 dbSNP
rs190213642 444 dbSNP
rs1309073521 450 dbSNP
rs1372757841 450 dbSNP
rs944882349 459 dbSNP
rs1013909203 477 dbSNP
rs1368566301 478 dbSNP
rs1296172494 479 dbSNP
rs912081720 486 dbSNP
rs1299254704 491 dbSNP
rs1311698527 496 dbSNP
rs561585661 501 dbSNP
rs896345147 506 dbSNP
rs368211307 509 dbSNP
rs1054905131 511 dbSNP
rs541266610 512 dbSNP
rs552303879 526 dbSNP
rs929387352 527 dbSNP
rs1489241834 530 dbSNP
rs1189151665 532 dbSNP
rs920648124 537 dbSNP
rs527930533 548 dbSNP
rs887536279 549 dbSNP
rs1414872731 550 dbSNP
rs973851347 551 dbSNP
rs1195605110 552 dbSNP
rs1305822255 553 dbSNP
rs1463812789 560 dbSNP
rs1355519449 562 dbSNP
rs1438816824 563 dbSNP
rs1292030473 564 dbSNP
rs1366913023 567 dbSNP
rs1164659819 570 dbSNP
rs1435919675 570 dbSNP
rs1299983654 571 dbSNP
rs1339972363 574 dbSNP
rs970023403 578 dbSNP
rs1022864838 587 dbSNP
rs374224689 589 dbSNP
rs1218876133 590 dbSNP
rs1483746756 600 dbSNP
rs992685848 607 dbSNP
rs1188661704 611 dbSNP
rs778506909 623 dbSNP
rs1249845834 624 dbSNP
rs1448179647 637 dbSNP
rs1167867452 643 dbSNP
rs1031929705 644 dbSNP
rs1040657272 645 dbSNP
rs1207611837 646 dbSNP
rs1349500358 653 dbSNP
rs1436179797 675 dbSNP
rs1481481914 681 dbSNP
rs140606942 688 dbSNP
rs545134240 694 dbSNP
rs576108743 696 dbSNP
rs1434222399 700 dbSNP
rs1284741563 703 dbSNP
rs1021369215 706 dbSNP
rs1380986675 707 dbSNP
rs986311564 711 dbSNP
rs1319786053 717 dbSNP
rs957490040 719 dbSNP
rs1274991581 720 dbSNP
rs996545213 721 dbSNP
rs899483370 722 dbSNP
rs967436804 726 dbSNP
rs556160720 732 dbSNP
rs1024711340 734 dbSNP
rs1238569926 735 dbSNP
rs558662947 735 dbSNP
rs960922802 737 dbSNP
rs1180473935 745 dbSNP
rs1040707582 751 dbSNP
rs1457947544 764 dbSNP
rs755459530 765 dbSNP
rs887608753 769 dbSNP
rs1400202618 770 dbSNP
rs1334675184 779 dbSNP
rs879503342 787 dbSNP
rs1350904575 788 dbSNP
rs1397268986 788 dbSNP
rs1229803601 791 dbSNP
rs1286074751 792 dbSNP
rs1327801158 799 dbSNP
rs993641114 802 dbSNP
rs767086157 806 dbSNP
rs373416613 807 dbSNP
rs929488418 812 dbSNP
rs574655119 813 dbSNP
rs944359051 814 dbSNP
rs1473141516 817 dbSNP
rs910814393 823 dbSNP
rs1184234631 825 dbSNP
rs1410055329 827 dbSNP
rs1469873013 831 dbSNP
rs1419971513 837 dbSNP
rs1173233143 839 dbSNP
rs1427410638 846 dbSNP
rs754327524 848 dbSNP
rs1190355453 849 dbSNP
rs1370862031 850 dbSNP
rs973498997 853 dbSNP
rs1487394959 856 dbSNP
rs948745221 864 dbSNP
rs1214287229 867 dbSNP
rs1334798875 871 dbSNP
rs532341326 872 dbSNP
rs1276086978 876 dbSNP
rs759148645 883 dbSNP
rs1217937351 884 dbSNP
rs1280249486 884 dbSNP
rs1265756217 885 dbSNP
rs375715485 890 dbSNP
rs915925853 892 dbSNP
rs977558375 903 dbSNP
rs1250152721 907 dbSNP
rs1437437255 911 dbSNP
rs1199875893 917 dbSNP
rs1379401259 924 dbSNP
rs1477081711 928 dbSNP
rs766761118 929 dbSNP
rs1390697513 932 dbSNP
rs1431621603 934 dbSNP
rs1385417811 945 dbSNP
rs1395570228 945 dbSNP
rs959951062 950 dbSNP
rs1373704824 951 dbSNP
rs1328783479 955 dbSNP
rs554803648 965 dbSNP
rs977694866 971 dbSNP
rs968570568 973 dbSNP
rs1231312877 982 dbSNP
rs1021818215 986 dbSNP
rs1272867837 993 dbSNP
rs958660347 995 dbSNP
rs1210587198 996 dbSNP
rs1033596295 1011 dbSNP
rs1450146486 1013 dbSNP
rs996618935 1015 dbSNP
rs1002069727 1017 dbSNP
rs1248766474 1018 dbSNP
rs1451229556 1022 dbSNP
rs1186621937 1023 dbSNP
rs1454386414 1031 dbSNP
rs951910424 1032 dbSNP
rs963760107 1033 dbSNP
rs993320256 1034 dbSNP
rs897583090 1035 dbSNP
rs1452306690 1040 dbSNP
rs1040088386 1042 dbSNP
rs1437847945 1048 dbSNP
rs1019297532 1066 dbSNP
rs1326152184 1068 dbSNP
rs1245968449 1069 dbSNP
rs1267673958 1071 dbSNP
rs1008980597 1082 dbSNP
rs1007856937 1084 dbSNP
rs888779065 1090 dbSNP
rs34148810 1093 dbSNP
rs534603318 1093 dbSNP
rs1466334373 1097 dbSNP
rs1186523274 1100 dbSNP
rs1260975025 1110 dbSNP
rs1424391022 1115 dbSNP
rs1189361208 1116 dbSNP
rs890739628 1120 dbSNP
rs756547297 1122 dbSNP
rs1366544624 1124 dbSNP
rs1474665099 1125 dbSNP
rs1050697899 1129 dbSNP
rs1390115128 1135 dbSNP
rs1464437449 1136 dbSNP
rs1455196451 1137 dbSNP
rs936223792 1138 dbSNP
rs904755288 1161 dbSNP
rs1397164051 1168 dbSNP
rs572303083 1171 dbSNP
rs773950779 1172 dbSNP
rs1232859704 1173 dbSNP
rs1485928860 1175 dbSNP
rs899312186 1180 dbSNP
rs1037811228 1181 dbSNP
rs917326198 1182 dbSNP
rs1483521000 1184 dbSNP
rs948815023 1187 dbSNP
rs78989292 1190 dbSNP
rs558763100 1196 dbSNP
rs1413689452 1197 dbSNP
rs938690373 1198 dbSNP
rs538759549 1199 dbSNP
rs924554715 1202 dbSNP
rs1377745012 1203 dbSNP
rs1466959578 1205 dbSNP
rs1320879968 1210 dbSNP
rs977348577 1212 dbSNP
rs376154310 1213 dbSNP
rs549516833 1214 dbSNP
rs1352562011 1215 dbSNP
rs1240815319 1216 dbSNP
rs927285049 1218 dbSNP
rs1401632807 1219 dbSNP
rs975208548 1220 dbSNP
rs879039927 1221 dbSNP
rs903829824 1224 dbSNP
rs1205599505 1225 dbSNP
rs957363361 1228 dbSNP
rs1479441108 1239 dbSNP
rs1176289062 1248 dbSNP
rs1267387481 1250 dbSNP
rs536196290 1251 dbSNP
rs1019369576 1252 dbSNP
rs1007930662 1255 dbSNP
rs972315788 1256 dbSNP
rs1372849979 1258 dbSNP
rs951067233 1259 dbSNP
rs1027005459 1260 dbSNP
rs1388575268 1264 dbSNP
rs993781761 1265 dbSNP
rs567146441 1271 dbSNP
rs1347019273 1274 dbSNP
rs1428575554 1275 dbSNP
rs899379726 1276 dbSNP
rs867579617 1279 dbSNP
rs1265679388 1286 dbSNP
rs1489291729 1290 dbSNP
rs113302498 1291 dbSNP
rs752807752 1291 dbSNP
rs766652133 1291 dbSNP
rs386787936 1292 dbSNP
rs894598464 1292 dbSNP
rs1208277556 1293 dbSNP
rs1454205172 1293 dbSNP
rs80164886 1293 dbSNP
rs1422049775 1294 dbSNP
rs375123238 1296 dbSNP
rs1486410793 1297 dbSNP
rs113182995 1306 dbSNP
rs1270451859 1306 dbSNP
rs1635399 1306 dbSNP
rs34630159 1306 dbSNP
rs1204826093 1307 dbSNP
rs1340522599 1308 dbSNP
rs1170258363 1309 dbSNP
rs1350677585 1312 dbSNP
rs1057133031 1313 dbSNP
rs1228852717 1322 dbSNP
rs1459674157 1325 dbSNP
rs938708024 1329 dbSNP
rs1028683030 1330 dbSNP
rs924655701 1337 dbSNP
rs1299735686 1339 dbSNP
rs904782975 1341 dbSNP
rs1376228165 1345 dbSNP
rs1396420907 1349 dbSNP
rs1042083799 1350 dbSNP
rs1213760708 1351 dbSNP
rs1307679221 1357 dbSNP
rs548111383 1358 dbSNP
rs1211495942 1359 dbSNP
rs946246645 1359 dbSNP
rs1464984413 1363 dbSNP
rs772893885 1364 dbSNP
rs914451578 1367 dbSNP
rs975281024 1368 dbSNP
rs1185082965 1369 dbSNP
rs1415038657 1372 dbSNP
rs1476281826 1379 dbSNP
rs144692279 1385 dbSNP
rs912342904 1386 dbSNP
rs986530338 1392 dbSNP
rs1181060550 1393 dbSNP
rs1322714471 1394 dbSNP
rs1343361925 1395 dbSNP
rs937408994 1396 dbSNP
rs565169280 1401 dbSNP
rs1381106508 1405 dbSNP
rs1025321267 1411 dbSNP
rs3179352 1412 dbSNP
rs1275621903 1416 dbSNP
rs963703226 1417 dbSNP
rs531708637 1418 dbSNP
rs562603203 1420 dbSNP
rs867727493 1421 dbSNP
rs1215731032 1423 dbSNP
rs542660820 1428 dbSNP
rs1018765427 1433 dbSNP
rs1186005107 1441 dbSNP
rs574027491 1442 dbSNP
rs560270968 1444 dbSNP
rs1287943951 1445 dbSNP
rs903230076 1447 dbSNP
rs1041719694 1448 dbSNP
rs1333768794 1450 dbSNP
rs1028715420 1454 dbSNP
rs541345097 1455 dbSNP
rs572342292 1464 dbSNP
rs1410337834 1465 dbSNP
rs1229900767 1466 dbSNP
rs1277213765 1468 dbSNP
rs1389865424 1468 dbSNP
rs1020990661 1469 dbSNP
rs1039628447 1470 dbSNP
rs558800596 1471 dbSNP
rs2286005 1472 dbSNP
rs150542689 1473 dbSNP
rs369136324 1473 dbSNP
rs370838201 1474 dbSNP
rs535953791 1474 dbSNP
rs149315725 1475 dbSNP
rs567290539 1475 dbSNP
rs547057736 1476 dbSNP
rs960332016 1476 dbSNP
rs1437525842 1477 dbSNP
rs962341717 1477 dbSNP
rs571576565 1478 dbSNP
rs1173343548 1479 dbSNP
rs879026614 1479 dbSNP
rs897169094 1479 dbSNP
rs1439297058 1480 dbSNP
rs1182905096 1482 dbSNP
rs1303321866 1482 dbSNP
rs991721445 1484 dbSNP
rs1230058357 1485 dbSNP
rs1268825295 1487 dbSNP
rs1338953706 1488 dbSNP
rs958921065 1489 dbSNP
rs944004010 1490 dbSNP
rs1212926217 1495 dbSNP
rs551569596 1497 dbSNP
rs911816172 1502 dbSNP
rs1245317261 1508 dbSNP
rs1051680708 1509 dbSNP
rs1182358765 1510 dbSNP
rs931838817 1510 dbSNP
rs1035830157 1514 dbSNP
rs1003412668 1519 dbSNP
rs1166685672 1521 dbSNP
rs200431216 1521 dbSNP
rs1391569370 1522 dbSNP
rs903304610 1523 dbSNP
rs375800423 1524 dbSNP
rs968516218 1543 dbSNP
rs1316613149 1546 dbSNP
rs912945021 1547 dbSNP
rs3179351 1548 dbSNP
rs1333038148 1549 dbSNP
rs1232745961 1550 dbSNP
rs893122828 1551 dbSNP
rs1039702838 1552 dbSNP
rs1443085923 1555 dbSNP
rs959934178 1556 dbSNP
rs1394570614 1562 dbSNP
rs565611155 1563 dbSNP
rs1398461314 1564 dbSNP
rs1415196475 1565 dbSNP
rs1474717367 1573 dbSNP
rs761967972 1574 dbSNP
rs562939791 1576 dbSNP
rs891014170 1577 dbSNP
rs1050983509 1578 dbSNP
rs929791157 1583 dbSNP
rs183781082 1584 dbSNP
rs191308240 1586 dbSNP
rs1315264902 1587 dbSNP
rs1196052871 1589 dbSNP
rs187239900 1596 dbSNP
rs1027089838 1597 dbSNP
rs1318848070 1602 dbSNP
rs1236714392 1607 dbSNP
rs996053402 1610 dbSNP
rs540227845 1611 dbSNP
rs897249999 1611 dbSNP
rs1008269756 1620 dbSNP
rs916262870 1627 dbSNP
rs572377260 1628 dbSNP
rs1182485250 1629 dbSNP
rs1213670832 1630 dbSNP
rs565126855 1631 dbSNP
rs1416802139 1636 dbSNP
rs1157804336 1637 dbSNP
rs1363723249 1639 dbSNP
rs1175895719 1640 dbSNP
rs544349484 1640 dbSNP
rs1374051804 1644 dbSNP
rs1285181705 1655 dbSNP
rs931868195 1657 dbSNP
rs928876553 1662 dbSNP
rs981666309 1663 dbSNP
rs1346864118 1670 dbSNP
rs1371607830 1671 dbSNP
rs1042909923 1675 dbSNP
rs768692820 1675 dbSNP
rs967935656 1678 dbSNP
rs377663933 1681 dbSNP
rs1011685935 1682 dbSNP
rs957412761 1687 dbSNP
rs1427988355 1693 dbSNP
rs1346491779 1697 dbSNP
rs1176093113 1698 dbSNP
rs1318556072 1711 dbSNP
rs1018295447 1715 dbSNP
rs1196090749 1716 dbSNP
rs912982523 1719 dbSNP
rs1171633251 1722 dbSNP
rs1373249550 1723 dbSNP
rs988963368 1726 dbSNP
rs1297662529 1727 dbSNP
rs1395348265 1729 dbSNP
rs149345743 1733 dbSNP
rs1301173095 1740 dbSNP
rs76100714 1741 dbSNP
rs1185329032 1742 dbSNP
rs1476421233 1749 dbSNP
rs1242832806 1751 dbSNP
rs1305378101 1755 dbSNP
rs980343126 1755 dbSNP
rs565152311 1756 dbSNP
rs150224533 1757 dbSNP
rs1282755937 1759 dbSNP
rs897000435 1761 dbSNP
rs1038179164 1764 dbSNP
rs1422160414 1765 dbSNP
rs1426917262 1774 dbSNP
rs1170237822 1775 dbSNP
rs1418588318 1777 dbSNP
rs1463064093 1779 dbSNP
rs974272679 1781 dbSNP
rs1393600180 1796 dbSNP
rs1431454373 1799 dbSNP
rs553747903 1804 dbSNP
rs1290362308 1812 dbSNP
rs916293990 1814 dbSNP
rs533504505 1816 dbSNP
rs961843314 1817 dbSNP
rs1213558108 1828 dbSNP
rs1015714723 1829 dbSNP
rs1293545369 1835 dbSNP
rs1336572244 1836 dbSNP
rs1212688902 1838 dbSNP
rs1054756590 1841 dbSNP
rs772102936 1851 dbSNP
rs1451519709 1852 dbSNP
rs939009790 1853 dbSNP
rs928930312 1854 dbSNP
rs982080797 1856 dbSNP
rs1193467063 1857 dbSNP
rs1258479408 1864 dbSNP
rs1312641859 1866 dbSNP
rs1451902729 1867 dbSNP
rs571610394 1869 dbSNP
rs558078722 1873 dbSNP
rs1162849898 1877 dbSNP
rs990282835 1878 dbSNP
rs996821889 1879 dbSNP
rs1161208158 1885 dbSNP
rs957443817 1891 dbSNP
rs1270208038 1895 dbSNP
rs1413648723 1897 dbSNP
rs1353132267 1898 dbSNP
rs1314363300 1899 dbSNP
rs1412602657 1901 dbSNP
rs1292067901 1902 dbSNP
rs538141981 1903 dbSNP
rs376586513 1908 dbSNP
rs776680528 1912 dbSNP
rs569461330 1916 dbSNP
rs759051612 1917 dbSNP
rs745908607 1918 dbSNP
rs994506417 1922 dbSNP
rs1186081374 1923 dbSNP
rs1236935049 1930 dbSNP
rs1179072953 1931 dbSNP
rs1405660058 1931 dbSNP
rs897039101 1932 dbSNP
rs549281952 1933 dbSNP
rs79075099 1937 dbSNP
rs938413659 1938 dbSNP
rs928362894 1939 dbSNP
rs1038616548 1940 dbSNP
rs1005337077 1943 dbSNP
rs529403217 1944 dbSNP
rs1054787376 1964 dbSNP
rs939042320 1966 dbSNP
rs1336037954 1967 dbSNP
rs1181294392 1976 dbSNP
rs1474279780 1978 dbSNP
rs201153295 1983 dbSNP
rs1240078543 1984 dbSNP
rs1281413873 1985 dbSNP
rs1635400 2002 dbSNP
rs1485862328 2004 dbSNP
rs974724455 2007 dbSNP
rs961598353 2011 dbSNP
rs908684955 2013 dbSNP
rs547016419 2015 dbSNP
rs1438940961 2021 dbSNP
rs553144571 2024 dbSNP
rs986966024 2027 dbSNP
rs946298617 2030 dbSNP
rs1171827742 2032 dbSNP
rs1452321344 2032 dbSNP
rs1396766839 2034 dbSNP
rs1250618627 2047 dbSNP
rs1326217491 2050 dbSNP
rs1398927955 2051 dbSNP
rs913444418 2052 dbSNP
rs1382847839 2055 dbSNP
rs1202191688 2058 dbSNP
rs1304839500 2060 dbSNP
rs1373890872 2063 dbSNP
rs1309128464 2065 dbSNP
rs1273662197 2069 dbSNP
rs1232508750 2072 dbSNP
rs1232109765 2084 dbSNP
rs1274697974 2085 dbSNP
rs1340301750 2088 dbSNP
rs771863263 2089 dbSNP
rs747752150 2097 dbSNP
rs1294722830 2099 dbSNP
rs1415082798 2102 dbSNP
rs1457391837 2103 dbSNP
rs1214455915 2104 dbSNP
rs1254786466 2112 dbSNP
rs911334901 2113 dbSNP
rs955457002 2117 dbSNP
rs985561948 2120 dbSNP
rs955457664 2123 dbSNP
rs533409550 2124 dbSNP
rs1028378798 2125 dbSNP
rs1476152909 2132 dbSNP
rs8059201 2136 dbSNP
rs1422224859 2143 dbSNP
rs879147833 2145 dbSNP
rs968036393 2146 dbSNP
rs961632286 2147 dbSNP
rs1385647448 2149 dbSNP
rs184111765 2150 dbSNP
rs754553941 2153 dbSNP
rs1459909565 2154 dbSNP
rs891650210 2157 dbSNP
rs894963071 2158 dbSNP
rs1420172049 2160 dbSNP
rs1165904520 2163 dbSNP
rs531615796 2171 dbSNP
rs192964796 2176 dbSNP
rs756515091 2177 dbSNP
rs906247019 2178 dbSNP
rs1175220531 2180 dbSNP
rs1481513185 2183 dbSNP
rs1233355763 2186 dbSNP
rs1042449618 2187 dbSNP
rs1044123791 2190 dbSNP
rs1213044695 2194 dbSNP
rs1332018813 2195 dbSNP
rs1190821606 2196 dbSNP
rs1261979277 2205 dbSNP
rs1475368614 2208 dbSNP
rs1166447071 2211 dbSNP
rs948424452 2211 dbSNP
rs573633262 2223 dbSNP
rs1163218517 2224 dbSNP
rs188658312 2225 dbSNP
rs1054695484 2234 dbSNP
rs542425636 2235 dbSNP
rs908767259 2237 dbSNP
rs1415643966 2238 dbSNP
rs1295135537 2242 dbSNP
rs1374554713 2243 dbSNP
rs986976652 2249 dbSNP
rs1243913348 2257 dbSNP
rs1261218717 2260 dbSNP
rs911407197 2263 dbSNP
rs184069497 2265 dbSNP
rs975485103 2267 dbSNP
rs1326597463 2268 dbSNP
rs968103256 2269 dbSNP
rs142823437 2274 dbSNP
rs956163210 2275 dbSNP
rs569468762 2280 dbSNP
rs1157175207 2282 dbSNP
rs1360294646 2285 dbSNP
rs558800860 2286 dbSNP
rs1315037484 2288 dbSNP
rs961386426 2289 dbSNP
rs539938276 2293 dbSNP
rs1016827752 2304 dbSNP
rs1395494027 2307 dbSNP
rs984020080 2308 dbSNP
rs1337448509 2312 dbSNP
rs1192931283 2318 dbSNP
rs1237884986 2326 dbSNP
rs907037889 2329 dbSNP
rs1348360499 2331 dbSNP
rs1212510329 2335 dbSNP
rs1254825471 2342 dbSNP
rs959252592 2346 dbSNP
rs1482764521 2351 dbSNP
rs1195863658 2352 dbSNP
rs1033481526 2354 dbSNP
rs1044154828 2356 dbSNP
rs1485277093 2362 dbSNP
rs1003338389 2364 dbSNP
rs117551000 2367 dbSNP
rs898223973 2370 dbSNP
rs764200235 2374 dbSNP
rs1317878248 2379 dbSNP
rs1175963649 2381 dbSNP
rs538684283 2386 dbSNP
rs566521450 2387 dbSNP
rs893495968 2389 dbSNP
rs1053422306 2390 dbSNP
rs1000458775 2392 dbSNP
rs538167515 2395 dbSNP
rs1304855320 2398 dbSNP
rs890004855 2400 dbSNP
rs752714303 2402 dbSNP
rs766344592 2403 dbSNP
rs934169696 2413 dbSNP
rs975516163 2420 dbSNP
rs1252516780 2426 dbSNP
rs1456087731 2431 dbSNP
rs922704211 2433 dbSNP
rs1238072559 2434 dbSNP
rs1037098827 2452 dbSNP
rs1193273239 2454 dbSNP
rs569415301 2455 dbSNP
rs940073959 2458 dbSNP
rs988554666 2459 dbSNP
rs1171430931 2461 dbSNP
rs1375078555 2462 dbSNP
rs1464106797 2465 dbSNP
rs193262955 2467 dbSNP
rs535625078 2468 dbSNP
rs567048198 2474 dbSNP
rs187552100 2477 dbSNP
rs959283878 2485 dbSNP
rs1396767352 2486 dbSNP
rs1031585110 2492 dbSNP
rs1199542319 2492 dbSNP
rs1217479294 2493 dbSNP
rs1427381754 2495 dbSNP
rs760630174 2496 dbSNP
rs926539117 2497 dbSNP
rs375742594 2498 dbSNP
rs1224433502 2504 dbSNP
rs771949537 2505 dbSNP
rs1485951143 2509 dbSNP
rs546740096 2517 dbSNP
rs1476999484 2521 dbSNP
rs1169992178 2523 dbSNP
rs761667070 2527 dbSNP
rs1418674455 2530 dbSNP
rs182274996 2538 dbSNP
rs189649723 2542 dbSNP
rs1454093503 2543 dbSNP
rs957742172 2545 dbSNP
rs1290483532 2550 dbSNP
rs9392 2550 dbSNP
rs1399025441 2563 dbSNP
rs567712178 2564 dbSNP
rs1356846879 2566 dbSNP
rs886768121 2570 dbSNP
rs1321682608 2571 dbSNP
rs570738685 2571 dbSNP
rs1216945147 2574 dbSNP
rs1288624672 2580 dbSNP
rs1487395275 2584 dbSNP
rs550968281 2600 dbSNP
rs1355000901 2604 dbSNP
rs1311323457 2614 dbSNP
rs1258259544 2615 dbSNP
rs1473805956 2619 dbSNP
rs531651621 2623 dbSNP
rs900059419 2624 dbSNP
rs375372620 2629 dbSNP
rs1432593255 2650 dbSNP
rs748838577 2653 dbSNP
rs1412972313 2654 dbSNP
rs890078518 2665 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions MCF7
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRR1045082. RNA binding protein: AGO2. Condition:Untreated ...

- Farazi TA; Ten Hoeve JJ; Brown M; et al., 2014, Genome biology.

Article - Farazi TA; Ten Hoeve JJ; Brown M; et al.
- Genome biology, 2014
BACKGROUND: Various microRNAs (miRNAs) are up- or downregulated in tumors. However, the repression of cognate miRNA targets responsible for the phenotypic effects of this dysregulation in patients remains largely unexplored. To define miRNA targets and associated pathways, together with their relationship to outcome in breast cancer, we integrated patient-paired miRNA-mRNA expression data with a set of validated miRNA targets and pathway inference. RESULTS: To generate a biochemically-validated set of miRNA-binding sites, we performed argonaute-2 photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (AGO2-PAR-CLIP) in MCF7 cells. We then defined putative miRNA-target interactions using a computational model, which ranked and selected additional TargetScan-predicted interactions based on features of our AGO2-PAR-CLIP binding-site data. We subselected modeled interactions according to the abundance of their constituent miRNA and mRNA transcripts in tumors, and we took advantage of the variability of miRNA expression within molecular subtypes to detect miRNA repression. Interestingly, our data suggest that miRNA families control subtype-specific pathways; for example, miR-17, miR-19a, miR-25, and miR-200b show high miRNA regulatory activity in the triple-negative, basal-like subtype, whereas miR-22 and miR-24 do so in the HER2 subtype. An independent dataset validated our findings for miR-17 and miR-25, and showed a correlation between the expression levels of miR-182 targets and overall patient survival. Pathway analysis associated miR-17, miR-19a, and miR-200b with leukocyte transendothelial migration. CONCLUSIONS: We combined PAR-CLIP data with patient expression data to predict regulatory miRNAs, revealing potential therapeutic targets and prognostic markers in breast cancer.
LinkOut: [PMID: 24398324]
CLIP-seq Support 1 for dataset SRR1045082
Method / RBP PAR-CLIP / AGO2
Cell line / Condition MCF7 / Untreated
Location of target site ENST00000262367.5 | 3UTR | AUCACUCUUAGACCAUGCUAAUGUUACUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 24398324 / SRX388831
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
UCEC -0.961 0.09 -1.000 0.5 3 Click to see details
BRCA 0.688 0.26 0.500 0.33 3 Click to see details
BLCA 0.685 0.26 1.000 0.5 3 Click to see details
HNSC 0.171 0.36 0.464 0.15 7 Click to see details
HNSC 0.171 0.36 0.464 0.15 7 Click to see details
HNSC 0.171 0.36 0.464 0.15 7 Click to see details
HNSC 0.171 0.36 0.464 0.15 7 Click to see details
HNSC 0.171 0.36 0.464 0.15 7 Click to see details
109 hsa-miR-1245a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006574 BRCA2 BRCA2, DNA repair associated 2 1
MIRT055432 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 2
MIRT063879 RASSF8 Ras association domain family member 8 2 6
MIRT077025 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT095775 GRPEL2 GrpE like 2, mitochondrial 2 10
MIRT099172 MAP3K4 mitogen-activated protein kinase kinase kinase 4 2 2
MIRT175616 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT456518 LYPLAL1 lysophospholipase like 1 2 2
MIRT464457 UGCG UDP-glucose ceramide glucosyltransferase 2 2
MIRT465747 TMPPE transmembrane protein with metallophosphoesterase domain 2 2
MIRT468257 SFXN4 sideroflexin 4 2 2
MIRT469216 RICTOR RPTOR independent companion of MTOR complex 2 2 2
MIRT472045 NPAT nuclear protein, coactivator of histone transcription 2 2
MIRT481795 APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 2 2
MIRT500154 CREBBP CREB binding protein 2 2
MIRT506514 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 4
MIRT506915 KBTBD8 kelch repeat and BTB domain containing 8 2 6
MIRT513901 GRB10 growth factor receptor bound protein 10 2 6
MIRT519128 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2 2
MIRT528121 FOXH1 forkhead box H1 2 2
MIRT528942 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT540580 CEP89 centrosomal protein 89 2 2
MIRT545858 ZNF264 zinc finger protein 264 2 4
MIRT547147 PGM3 phosphoglucomutase 3 2 2
MIRT547434 MED4 mediator complex subunit 4 2 2
MIRT554650 ROBO1 roundabout guidance receptor 1 2 2
MIRT558524 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT559762 ABHD5 abhydrolase domain containing 5 2 2
MIRT560438 GOLGA7B golgin A7 family member B 2 2
MIRT561974 LRRC59 leucine rich repeat containing 59 2 2
MIRT562442 DDIT4 DNA damage inducible transcript 4 2 2
MIRT563489 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT568265 BMP2K BMP2 inducible kinase 2 2
MIRT572522 KIAA0232 KIAA0232 2 2
MIRT612801 LSM14A LSM14A, mRNA processing body assembly factor 2 2
MIRT621533 ZNF507 zinc finger protein 507 2 2
MIRT625205 GSTCD glutathione S-transferase C-terminal domain containing 2 2
MIRT625615 ZNF84 zinc finger protein 84 2 2
MIRT629215 C12orf66 chromosome 12 open reading frame 66 2 2
MIRT629509 AS3MT arsenite methyltransferase 2 2
MIRT629769 STK25 serine/threonine kinase 25 2 2
MIRT630908 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT632508 RAB13 RAB13, member RAS oncogene family 2 2
MIRT636871 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT637106 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT637332 FAM9B family with sequence similarity 9 member B 2 2
MIRT637553 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT637639 ZNF431 zinc finger protein 431 2 2
MIRT637836 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT638326 RNF11 ring finger protein 11 2 2
MIRT638393 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT642450 CLUAP1 clusterin associated protein 1 2 2
MIRT642616 APOPT1 apoptogenic 1, mitochondrial 2 2
MIRT643133 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT644324 NFKBID NFKB inhibitor delta 2 2
MIRT645150 DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease 2 2
MIRT645673 ADK adenosine kinase 2 2
MIRT646091 MGST3 microsomal glutathione S-transferase 3 2 2
MIRT646858 SLC35E4 solute carrier family 35 member E4 2 2
MIRT650153 ZNF426 zinc finger protein 426 2 2
MIRT652483 TMEM181 transmembrane protein 181 2 2
MIRT653790 SIRPA signal regulatory protein alpha 2 2
MIRT655526 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 2 2
MIRT657077 JPH2 junctophilin 2 2 2
MIRT657322 HOOK3 hook microtubule tethering protein 3 2 2
MIRT662036 FUT2 fucosyltransferase 2 2 2
MIRT662322 ADM2 adrenomedullin 2 2 2
MIRT663211 DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2 2
MIRT663559 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663937 ZNF554 zinc finger protein 554 2 2
MIRT664689 EIF2B2 eukaryotic translation initiation factor 2B subunit beta 2 2
MIRT664709 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT665291 ZFP14 ZFP14 zinc finger protein 2 2
MIRT665572 TXNL1 thioredoxin like 1 2 2
MIRT667068 PAOX polyamine oxidase 2 2
MIRT667304 MYO5A myosin VA 2 2
MIRT667442 METTL14 methyltransferase like 14 2 2
MIRT668048 GTPBP10 GTP binding protein 10 2 2
MIRT669604 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT671088 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT674361 SLC35E3 solute carrier family 35 member E3 2 2
MIRT674962 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT676394 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676819 AGMAT agmatinase 2 2
MIRT676891 ENSA endosulfine alpha 2 2
MIRT677059 ZNF34 zinc finger protein 34 2 2
MIRT678424 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678735 SRCAP Snf2 related CREBBP activator protein 2 2
MIRT678930 XPOT exportin for tRNA 2 2
MIRT678954 MYADM myeloid associated differentiation marker 2 2
MIRT679228 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679765 TLR6 toll like receptor 6 2 2
MIRT681992 HRH4 histamine receptor H4 2 2
MIRT687405 NSUN4 NOP2/Sun RNA methyltransferase family member 4 2 2
MIRT694570 RBMXL1 RNA binding motif protein, X-linked like 1 2 2
MIRT698449 TM4SF1 transmembrane 4 L six family member 1 2 2
MIRT706406 HAS2 hyaluronan synthase 2 2 2
MIRT706582 ZNF432 zinc finger protein 432 2 2
MIRT706838 VHLL VHL like 2 2
MIRT706909 DVL3 dishevelled segment polarity protein 3 2 2
MIRT707052 TRPV2 transient receptor potential cation channel subfamily V member 2 2 2
MIRT708583 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT708988 CABP4 calcium binding protein 4 2 2
MIRT713041 ADRA2B adrenoceptor alpha 2B 2 2
MIRT713731 SUCO SUN domain containing ossification factor 2 2
MIRT714968 RAB21 RAB21, member RAS oncogene family 2 2
MIRT717485 PDE4DIP phosphodiesterase 4D interacting protein 2 2
MIRT722826 KLK2 kallikrein related peptidase 2 2 2
MIRT723305 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (500nM)
hsa-miR-1245a Trametinib 11707110 NSC758246 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (M14) (1uM)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-1245a Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission