miRTarBase - #MIRT505971


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pre-miRNA Information
pre-miRNA hsa-mir-5691   
Genomic Coordinates chr11: 9090312 - 9090379
Description Homo sapiens miR-5691 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-5691
Sequence 9| UUGCUCUGAGCUCCGAGAAAGC |30
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1042238449 3 dbSNP
rs554804494 11 dbSNP
rs1172229307 13 dbSNP
rs112511786 14 dbSNP
Putative Targets

Gene Information
Gene Symbol RAB11FIP1   
Synonyms NOEL1A, RCP, rab11-FIP1
Description RAB11 family interacting protein 1
Transcript NM_001002814   
Other Transcripts NM_025151   
Expression
Putative miRNA Targets on RAB11FIP1
3'UTR of RAB11FIP1
(miRNA target sites are highlighted)		 
>RAB11FIP1|NM_001002814|3'UTR
   1 ATCAGCAGAAAAAAAACACCGAGACGTTTCTGTGACTTCACTTTCACCTGCTCCAGGGGTCAAGGACTTGCCTTGCCTGA
  81 TAACCAGCCAGCAGGCTCCGAATCACCATCTCCCTCACATGTTATCCGGCAAGAGTGAATTCTACCAATGGAAGCCAGGT
 161 TAATGATTACAATTAATCTTTTACTGTACATTCCCAAGGCTTTAGTTTTAAATGCCACTGTGCCTTTAACAAGGTTGTAA
 241 ATATTTTATGCCCACCAGAGATGTGGTCATAAGATCTGATCCTGAGCCAGAGATTCAGATGGCACAGGAAGTATTCATGT
 321 ATTTTAACACTGGGGTTTTCTTTCTTTCATACTGAGATTTTTTTTCAGTATGTATCCTCCAGCTCTTAAAGCTTACCTGA
 401 GAAAGCTTTAAATGAGAAAAGGACCATGCGATTGGTGCTGTGTTACATACACATACTTTCTTGGCTTCTGAGTAGCTCAG
 481 GTGTGGCTTTTGGCTGCAGATGTTAAATTTTGATACCATGTAAACCTACCCAGCTTCTCAGACTTGGGTCTTGTTTTTTG
 561 ATGGGAACAGAGGTGTTTAGAGAAAGCCTCTGAGTATGCCTTTCAGATTTTGAACAAGCGGCCTTTTCTAAACATCGACT
 641 TCTACTACTCTCTAGCCTTAAAATACCTTCTGCTTAGATCCAGGGCCCTTCTACTGGAGATAGGAAAAGTAGAATTCAGG
 721 AATTAAAAGAATTACTCTTTATTCAATTTGAGGAACTTGGTGAAAGCCCCTCCTCTTATGACAGCCAGGTTCCTGCTGGC
 801 TAGACCAGCCTATTCAGCGCTTTGCTAGGGGATTGGGTGGTCCACGCACTCGCTAATACAGTTCTCCAGGTGTGGAATGA
 881 TGTCAATACGATTGCTTGGCCTTTTCCCCCTGTGCCTTTGCTCGGTGCTCTGGTTTCCTCAGCAACACTCCTTGTAAGGG
 961 GCAGAGACAGGGTCCACCAACTCCCCAAGATGAAGAAGCCCCTTCAGGCCAGTCGTGGTGGCTCATGCCTGTAATCCCAG
1041 CACTTTGCAAGGCCGAGGAGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGCGAAACCCCATC
1121 TCTACTAAAAATACAAAAATTAGCTTGGCATGGTGGTGCGTGCCTGTAATCCCAGCTACTCGGGAGGCTGGGGCAGGAGA
1201 ATTGCTTGAACTTGGGAGATGGAGGCTGCAGCGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAAGAGTTTTTTTA
1281 AGACTCTTAAAAAAAGAGCCTGGGCAATTTTTTTAAGACTCTGTCTTAAAAAAAACTAAAAAGAAAAAAAGAAGCCCCTT
1361 CACTCTACAGGGGACAGGAGACCATGGATTGGACCCCAAAGGGATTGAACTGCATCTGCATGTCTGTCCTTTGAACACTT
1441 TCTCTCCCTGCCCAAAAGGAAACCCAAATTATTTGTGGGATACTGGGGAAATTGTAGTGAAGGGCTTAATGTAGTTAATA
1521 AAAGTTAAAAGTCAGTAGAAAACAGGTGCCTCAGCCTTCAAATGGTTGCTTTTTTTCCATTTTCCCTCATGAATAGACTC
1601 ACCAGCATTTTACCCCCTTGTTATAAAACTGTGCAGAGCAAGAAGATGATACTTATTTTTGAATTTGTATTTTTAAAACT
1681 AGATTTATAGACTTTTTTTTTTTTTAACTAGGGCACTTGCTTCCTTCTTAGCTAAAAGCACCAGCTGAGATTTTTCAGGT
1761 AATTTTGTTGTTACTCACTTAAGACTGGAATTAGAATGTTTCTGGTATTTCTCATTTTTTTCCCTGGCTATGATAGAATC
1841 TCATCTAATCTTGACATCTCTCCTAGGGGAAGAATATCACAGGCTAATAGCGTGGTTGGGGGTGAAGATGATAGCAGTTA
1921 TTAAATCAGGAATCTCTTTTATGTGTGTCCTTGTTACATTGAGGTTAAGAGACAAAATCATTGGCAGTGCAATCTCTTTC
2001 CAGGATTTCGTTTGCTGTGGCATTGGTTATATCAGAGCACTTTAATCTGAAGGATGATACTGTAACTTGATTTATCTAAT
2081 TAGCTTTTAATTATCTACAGCTATTTTATTTTATTTAATTCTCTCCTACAGTACTGGGACCACTGTAAACTTCTCAGATG
2161 ACTTGTATTTTTGTAGTGCTATGAAATTTATTTACATACTTATAAAGAAAACTGTATGTTCACTTGAACTCTGAAAATGT
2241 ACATGTATGGCTGGACGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGAATCACTTGATTGA
2321 GGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAAAATACAGAAATTAGCTGGGTGTGG
2401 TGGCAGACAGCTGTAATCTCAGCTGCTCGGGAGGCTGAGGCACAAGAATCGCTTGAGCCAGGGAGGTGGAGGTTGCAGTG
2481 AGCTGAGATCACATCATTGCACTCCAGCCTGGGCAACGGGCGAGACTCTGTCTCAAAAAAAAGAAAGAAAGAAAAGGTAC
2561 ATGTATATATTTGTCCTGCATTATGTTTTTTACTTGATATAAATGTATTTTTACTGTGATAGTCCAAGTGCCCTGGGGGG
2641 CAGGTGTGCTCTATGTGGTTCTTCTTCCATTGGAGAGCTGGCGTAGAGATCTGCAGTGTTCACAAGGATGTTGGTTTGGA
2721 GATGTCTGCTGCTAGGACCTGGGGTGTGTGACTCAGTCCATATGAGAGGGACATCTGGGTGGAGGAGTAAATTCCTGTGC
2801 TCTGAAATGCCACTTGGTAGCTCTGGACAATGAAGGACAATTGACTCAAGGGTGCCTGGCTTCTGCTGCTGCTGGGAAAA
2881 AATTCAGTTTATAGCATTCCTGCACCTCCCAAAGTAGATAACCTGGAGGTCATTCAGTTAACAACTGTCCCTGAGGACTC
2961 AGTTTTGGGGGAGGGGTTATCTGGGAGAAGCTTTAGCCTGTTCTGAGCCATTAGGAGACATTAGTGAATTGGAGCACTGG
3041 AGAATCCTACAAATGGCCTATGTCTCAGAAGAGCTGGGACCTCCTTCCAGCTGCTGCAGATGCTGACAGGCCCTGGGAGG
3121 CTGCTGTGCTCTGGAGAAGCTGGAGCAGCTCATTTCTTGGCCTAGCCTGGCTGCCTCAGAAAGAGCAGTCAGGACTTGAG
3201 GGAAGCATCAAATTCTATACCCATAAACTGCAGTTGGAAGTCAGCTTTTTGAAATGTCCAGCCTTTGCCCAATTGTTTCA
3281 GATCATCTCATGCCTCAGGCTTTGGCAGGTATCCTGCCCTCCATCTTATTCCAGTGTGTTCACCTCATCAAGGCAGCAGA
3361 GTGGATGAAGGAGTAAGTCTGCCCTTTGCCATACTGAACAGCTGTGGACCCCGATTGGTGAGGGCTCTGCATATGCCTGT
3441 ATGAAGGAGATACAGGTGTGTGTGCACATGCCGGTATGAAGAAGACACAGGCATGTGCTTCTCAGTTTTGCTAACAGTGG
3521 GAGCTCAACGGGGCAGAGGGAGGAAGGTCCATGATGCTCAGCCACATACTGTAGAGAGAGGCAATTTAATGTTAAATGAC
3601 GCACCATCCTCCCTCCCACCCTTCTCCCAGTCAACTTTTTTTCTTTTTCTAGAACTACTAATTATCTCTCAAGGCTGAAA
3681 AATTAATTGCCTTAGGTGGAGAACTTAATTCCTAGTATCCACCAAACTTAACTCCGTATCTCCATATGGTGTCTCCATAT
3761 CTACTGTGTGAGCTACTTAACTGACGCCCTCTTCCTCCAACTGAAGGATCGCCCAACGTTTTTGGATTATAGAATTATTA
3841 TTTCCTGCTTTCTTTCTTTGGGACTTTTGAATTTCTTTGGTTTCGTTTTTAAGAAGTAACCCAACATTTCCTACAACACT
3921 AAATAAAATGGTACTTACCTTTCAAAGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgaaagAGCC--UCGAGUCUCGUu 5'
                |:||  |  |||||||| 
Target 5' gtggcaTTGGTTATATCAGAGCAc 3'
 2017 - 2040 150.00 -14.50
2 
miRNA  3' cgaaagagccuCGAGUCUCGUu 5'
                     |: ||||||| 
Target 5' gttataaaactGTGCAGAGCAa 3'
 1620 - 1641 143.00 -11.60
3 
miRNA  3' cgaaagAGCCUCGA---GUCUCGUu 5'
                | ||||||   |:|:||| 
Target 5' taacagTGGGAGCTCAACGGGGCAg 3'
 3512 - 3536 128.00 -18.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30155141 3 COSMIC
COSN2531325 8 COSMIC
COSN26991252 9 COSMIC
COSN31601560 12 COSMIC
COSN32053186 45 COSMIC
COSN30184655 48 COSMIC
COSN31508491 53 COSMIC
COSN30496455 54 COSMIC
COSN30454619 57 COSMIC
COSN30127604 91 COSMIC
COSN32053387 94 COSMIC
COSN31540429 96 COSMIC
COSN9633985 102 COSMIC
COSN30125919 121 COSMIC
COSN30477816 126 COSMIC
COSN23521587 177 COSMIC
COSN31604971 178 COSMIC
COSN30130921 238 COSMIC
COSN26538045 287 COSMIC
COSN28665954 496 COSMIC
COSN27884021 619 COSMIC
COSN8083300 845 COSMIC
COSN26645843 1267 COSMIC
COSN30696077 1288 COSMIC
COSN30551869 1308 COSMIC
COSN31606126 1423 COSMIC
COSN30175492 1459 COSMIC
COSN28860360 1463 COSMIC
COSN18749506 1693 COSMIC
COSN9633984 1696 COSMIC
COSN26415122 1805 COSMIC
COSN31561414 1892 COSMIC
COSN9633983 1910 COSMIC
COSN19663760 1937 COSMIC
COSN31534983 2009 COSMIC
COSN31516797 2121 COSMIC
COSN31516247 2134 COSMIC
COSN20947361 2306 COSMIC
COSN31523997 2618 COSMIC
COSN30173888 2651 COSMIC
COSN31523546 2918 COSMIC
COSN31532136 2951 COSMIC
COSN22028819 3053 COSMIC
COSN17076080 3615 COSMIC
COSN17076079 3753 COSMIC
COSN27099496 3831 COSMIC
COSN21420088 4051 COSMIC
COSN21474019 4204 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1470588864 2 dbSNP
rs767929651 3 dbSNP
rs1174331540 5 dbSNP
rs1432971309 6 dbSNP
rs755500140 8 dbSNP
rs751151910 9 dbSNP
rs1447943083 12 dbSNP
rs1389598430 13 dbSNP
rs1469356807 14 dbSNP
rs765961978 16 dbSNP
rs762764236 17 dbSNP
rs768132133 17 dbSNP
rs778506557 17 dbSNP
rs772748544 18 dbSNP
rs748948361 19 dbSNP
rs771529024 20 dbSNP
rs1156321069 21 dbSNP
rs750295322 21 dbSNP
rs779916890 21 dbSNP
rs201814791 25 dbSNP
rs776448220 26 dbSNP
rs768621870 31 dbSNP
rs918286144 34 dbSNP
rs746927581 39 dbSNP
rs1334972343 40 dbSNP
rs1230127027 41 dbSNP
rs1362676433 45 dbSNP
rs1236565203 46 dbSNP
rs1008368001 47 dbSNP
rs1329352261 53 dbSNP
rs528549475 57 dbSNP
rs1260777715 59 dbSNP
rs868749900 71 dbSNP
rs1009225141 80 dbSNP
rs747801928 88 dbSNP
rs778476914 91 dbSNP
rs570861909 95 dbSNP
rs1417733189 97 dbSNP
rs985310097 99 dbSNP
rs1412989176 100 dbSNP
rs552151281 103 dbSNP
rs193169185 116 dbSNP
rs74817207 127 dbSNP
rs73673896 128 dbSNP
rs1303390819 130 dbSNP
rs967404150 134 dbSNP
rs749144512 139 dbSNP
rs949164705 144 dbSNP
rs908667790 166 dbSNP
rs1350878635 175 dbSNP
rs1475462151 186 dbSNP
rs78217766 208 dbSNP
rs893406627 216 dbSNP
rs1210154936 228 dbSNP
rs527422569 229 dbSNP
rs779864133 234 dbSNP
rs1207919111 251 dbSNP
rs1435370450 253 dbSNP
rs919907084 255 dbSNP
rs1001716035 256 dbSNP
rs559865451 261 dbSNP
rs1222214990 264 dbSNP
rs964661157 266 dbSNP
rs907396759 268 dbSNP
rs1196536738 277 dbSNP
rs912781713 282 dbSNP
rs1249640045 286 dbSNP
rs1371395640 287 dbSNP
rs1427814632 288 dbSNP
rs1045483358 290 dbSNP
rs370902261 295 dbSNP
rs1404057151 299 dbSNP
rs1291458087 300 dbSNP
rs1225216314 305 dbSNP
rs541276711 306 dbSNP
rs1369199242 310 dbSNP
rs929739137 312 dbSNP
rs967514570 318 dbSNP
rs1294300845 326 dbSNP
rs1347288332 328 dbSNP
rs1305227575 334 dbSNP
rs1283761198 339 dbSNP
rs1275913188 348 dbSNP
rs1404094704 351 dbSNP
rs896804646 355 dbSNP
rs1009256044 356 dbSNP
rs1248688880 357 dbSNP
rs1488964498 361 dbSNP
rs1038053882 366 dbSNP
rs1186140263 366 dbSNP
rs941236289 373 dbSNP
rs1451381033 374 dbSNP
rs1170434003 375 dbSNP
rs1390668433 381 dbSNP
rs1423770948 398 dbSNP
rs1162360861 399 dbSNP
rs1309476749 411 dbSNP
rs1351390755 412 dbSNP
rs1436806475 423 dbSNP
rs1287902959 424 dbSNP
rs757595888 429 dbSNP
rs572847306 430 dbSNP
rs1165623833 444 dbSNP
rs1382619863 452 dbSNP
rs1001848433 457 dbSNP
rs933834213 461 dbSNP
rs1322661429 464 dbSNP
rs1215393430 475 dbSNP
rs922470020 477 dbSNP
rs905115480 497 dbSNP
rs2411200 499 dbSNP
rs1189222464 510 dbSNP
rs976176581 520 dbSNP
rs557928781 529 dbSNP
rs1020216355 530 dbSNP
rs1199260638 532 dbSNP
rs990110827 537 dbSNP
rs2411201 541 dbSNP
rs886928591 548 dbSNP
rs1415759462 554 dbSNP
rs957582213 555 dbSNP
rs1157958088 566 dbSNP
rs1047202345 571 dbSNP
rs1458374743 572 dbSNP
rs931404916 586 dbSNP
rs1381400756 587 dbSNP
rs1446509937 596 dbSNP
rs1034554606 599 dbSNP
rs1380373910 612 dbSNP
rs919995418 619 dbSNP
rs1331414189 622 dbSNP
rs1209580082 625 dbSNP
rs1182831389 628 dbSNP
rs1460020659 634 dbSNP
rs1437440802 636 dbSNP
rs1420250681 637 dbSNP
rs1239091582 644 dbSNP
rs1271019763 646 dbSNP
rs1176359349 650 dbSNP
rs747760244 650 dbSNP
rs1409474440 655 dbSNP
rs1473409064 658 dbSNP
rs1040119661 661 dbSNP
rs1159409249 663 dbSNP
rs1002232094 665 dbSNP
rs942679613 670 dbSNP
rs1412216217 673 dbSNP
rs912843964 674 dbSNP
rs1441950317 675 dbSNP
rs1306627558 678 dbSNP
rs1352708424 680 dbSNP
rs1325654794 683 dbSNP
rs987060764 685 dbSNP
rs1222746325 686 dbSNP
rs571652529 687 dbSNP
rs1262599256 691 dbSNP
rs1442996190 699 dbSNP
rs990253669 701 dbSNP
rs1024921446 703 dbSNP
rs1281020369 710 dbSNP
rs1483899337 716 dbSNP
rs993903033 732 dbSNP
rs1428111709 755 dbSNP
rs1032055689 756 dbSNP
rs1334802569 762 dbSNP
rs142733672 764 dbSNP
rs560214309 767 dbSNP
rs1406098043 773 dbSNP
rs1306680502 774 dbSNP
rs941013454 775 dbSNP
rs1176376808 777 dbSNP
rs1468654518 782 dbSNP
rs1372822902 798 dbSNP
rs1414718190 799 dbSNP
rs557271301 806 dbSNP
rs188608371 809 dbSNP
rs568279316 812 dbSNP
rs933928029 818 dbSNP
rs922449247 819 dbSNP
rs1338794862 827 dbSNP
rs1227638453 834 dbSNP
rs1272322882 836 dbSNP
rs541488455 841 dbSNP
rs1205519452 843 dbSNP
rs553086121 845 dbSNP
rs183244246 846 dbSNP
rs574299676 847 dbSNP
rs913325354 851 dbSNP
rs990225805 852 dbSNP
rs1242564196 854 dbSNP
rs957363746 865 dbSNP
rs544944251 871 dbSNP
rs1459905558 875 dbSNP
rs980366603 879 dbSNP
rs1039789069 880 dbSNP
rs1324432502 882 dbSNP
rs1286171518 883 dbSNP
rs942727556 886 dbSNP
rs891113677 889 dbSNP
rs1277418599 890 dbSNP
rs1229036736 897 dbSNP
rs1264711151 898 dbSNP
rs1353951193 899 dbSNP
rs972068330 900 dbSNP
rs1382915975 904 dbSNP
rs552288191 910 dbSNP
rs1290100732 911 dbSNP
rs1024451984 923 dbSNP
rs1051309012 924 dbSNP
rs1249332053 925 dbSNP
rs1450715345 929 dbSNP
rs192690989 930 dbSNP
rs1187427169 932 dbSNP
rs1367140729 942 dbSNP
rs946318038 953 dbSNP
rs1347458543 954 dbSNP
rs1384439940 955 dbSNP
rs994747098 960 dbSNP
rs756032268 962 dbSNP
rs1455719794 970 dbSNP
rs961081879 971 dbSNP
rs1322707919 973 dbSNP
rs148898575 975 dbSNP
rs1435774827 988 dbSNP
rs562293607 1005 dbSNP
rs376713254 1007 dbSNP
rs544144122 1010 dbSNP
rs147831433 1014 dbSNP
rs1284440354 1015 dbSNP
rs1206434660 1017 dbSNP
rs1269521393 1018 dbSNP
rs1464943038 1019 dbSNP
rs1200411275 1024 dbSNP
rs998086367 1025 dbSNP
rs901086974 1026 dbSNP
rs980534927 1029 dbSNP
rs1384736138 1030 dbSNP
rs1042187802 1031 dbSNP
rs1471771337 1032 dbSNP
rs969485336 1033 dbSNP
rs945201263 1038 dbSNP
rs1459973336 1042 dbSNP
rs1412854859 1048 dbSNP
rs1469310707 1049 dbSNP
rs1302199033 1051 dbSNP
rs1243793034 1053 dbSNP
rs915112797 1054 dbSNP
rs370584619 1055 dbSNP
rs577883708 1059 dbSNP
rs1349621556 1061 dbSNP
rs1289782903 1065 dbSNP
rs375257916 1068 dbSNP
rs1231798765 1070 dbSNP
rs1359672510 1073 dbSNP
rs927268292 1073 dbSNP
rs1201521280 1078 dbSNP
rs1024661338 1079 dbSNP
rs879527388 1082 dbSNP
rs1482265733 1086 dbSNP
rs144380138 1087 dbSNP
rs558719095 1089 dbSNP
rs1432688401 1100 dbSNP
rs1137155 1102 dbSNP
rs764479149 1106 dbSNP
rs547965340 1109 dbSNP
rs186623218 1110 dbSNP
rs995380490 1115 dbSNP
rs1369748080 1117 dbSNP
rs1137156 1118 dbSNP
rs1407725795 1120 dbSNP
rs1309476959 1121 dbSNP
rs112555767 1124 dbSNP
rs1385858937 1131 dbSNP
rs112142124 1134 dbSNP
rs564152109 1141 dbSNP
rs1018802363 1143 dbSNP
rs953790590 1146 dbSNP
rs1006955154 1151 dbSNP
rs1340519349 1156 dbSNP
rs545942111 1159 dbSNP
rs1027967268 1160 dbSNP
rs540603062 1163 dbSNP
rs1305313722 1166 dbSNP
rs1189662470 1167 dbSNP
rs891179408 1177 dbSNP
rs540830085 1179 dbSNP
rs900869580 1181 dbSNP
rs1161844893 1182 dbSNP
rs1430391492 1187 dbSNP
rs1042692031 1191 dbSNP
rs1389410891 1198 dbSNP
rs1009460755 1204 dbSNP
rs893627323 1212 dbSNP
rs1178949443 1216 dbSNP
rs1381887402 1218 dbSNP
rs774473467 1220 dbSNP
rs563239856 1221 dbSNP
rs770993206 1223 dbSNP
rs1355451900 1226 dbSNP
rs1482137146 1229 dbSNP
rs541468937 1232 dbSNP
rs182314147 1233 dbSNP
rs1444379600 1234 dbSNP
rs1389844930 1237 dbSNP
rs1164229231 1238 dbSNP
rs190026258 1241 dbSNP
rs573129020 1243 dbSNP
rs576993327 1244 dbSNP
rs947843176 1246 dbSNP
rs1275850386 1254 dbSNP
rs1321473855 1257 dbSNP
rs1233242838 1258 dbSNP
rs972963928 1260 dbSNP
rs111559209 1261 dbSNP
rs991829147 1265 dbSNP
rs1339566649 1274 dbSNP
rs1273475454 1279 dbSNP
rs1246017713 1280 dbSNP
rs111410466 1286 dbSNP
rs1310012652 1296 dbSNP
rs1227153432 1301 dbSNP
rs951026050 1303 dbSNP
rs1374779015 1308 dbSNP
rs752096250 1310 dbSNP
rs1408398477 1312 dbSNP
rs1422975928 1313 dbSNP
rs1370145860 1314 dbSNP
rs1448218835 1317 dbSNP
rs1164478325 1320 dbSNP
rs1318203610 1321 dbSNP
rs1351191891 1323 dbSNP
rs1459685233 1329 dbSNP
rs1461628495 1335 dbSNP
rs780962572 1336 dbSNP
rs918543031 1336 dbSNP
rs1366762982 1339 dbSNP
rs558354807 1343 dbSNP
rs1164258510 1345 dbSNP
rs754723072 1346 dbSNP
rs973972023 1346 dbSNP
rs1423164762 1347 dbSNP
rs1412642463 1350 dbSNP
rs962883981 1351 dbSNP
rs1481966972 1355 dbSNP
rs780644918 1358 dbSNP
rs1222738797 1362 dbSNP
rs1489278771 1370 dbSNP
rs1018122670 1372 dbSNP
rs771581756 1374 dbSNP
rs984309148 1375 dbSNP
rs1263161642 1376 dbSNP
rs1243502728 1378 dbSNP
rs1317984571 1386 dbSNP
rs1290759132 1387 dbSNP
rs1007104649 1389 dbSNP
rs1266357846 1395 dbSNP
rs1466289000 1396 dbSNP
rs774004854 1397 dbSNP
rs955491483 1400 dbSNP
rs1242588506 1404 dbSNP
rs1482807823 1407 dbSNP
rs1179841898 1414 dbSNP
rs953739955 1420 dbSNP
rs1029662550 1421 dbSNP
rs1157931682 1422 dbSNP
rs73598921 1437 dbSNP
rs891789031 1443 dbSNP
rs761368995 1444 dbSNP
rs1169789297 1471 dbSNP
rs1000472151 1473 dbSNP
rs569826288 1488 dbSNP
rs1409375094 1492 dbSNP
rs965396391 1497 dbSNP
rs549740677 1498 dbSNP
rs1421375210 1518 dbSNP
rs7003704 1519 dbSNP
rs1480642363 1521 dbSNP
rs77766600 1524 dbSNP
rs1286630376 1531 dbSNP
rs950226137 1555 dbSNP
rs1331353684 1559 dbSNP
rs1189120194 1565 dbSNP
rs1224344225 1565 dbSNP
rs1311601941 1570 dbSNP
rs1207897807 1576 dbSNP
rs566351205 1579 dbSNP
rs893741852 1586 dbSNP
rs917714416 1604 dbSNP
rs1485849191 1607 dbSNP
rs1056220311 1613 dbSNP
rs929654615 1614 dbSNP
rs1203199777 1615 dbSNP
rs1032094969 1618 dbSNP
rs773843067 1624 dbSNP
rs1158705620 1630 dbSNP
rs1423845917 1633 dbSNP
rs1002001030 1640 dbSNP
rs974121330 1642 dbSNP
rs1178838913 1646 dbSNP
rs1376465871 1647 dbSNP
rs555062653 1656 dbSNP
rs962669543 1656 dbSNP
rs911095442 1667 dbSNP
rs905060280 1687 dbSNP
rs1323308015 1688 dbSNP
rs985313732 1690 dbSNP
rs183305716 1691 dbSNP
rs1029734599 1693 dbSNP
rs1282334174 1693 dbSNP
rs532717441 1694 dbSNP
rs1010258806 1697 dbSNP
rs1393399563 1701 dbSNP
rs1204109902 1705 dbSNP
rs1272200477 1706 dbSNP
rs1396140479 1706 dbSNP
rs1476725731 1706 dbSNP
rs76238618 1706 dbSNP
rs879065659 1706 dbSNP
rs1167165269 1708 dbSNP
rs199708916 1708 dbSNP
rs1372766672 1709 dbSNP
rs1297741836 1710 dbSNP
rs1323087933 1716 dbSNP
rs565451368 1719 dbSNP
rs1044871963 1730 dbSNP
rs1438624942 1736 dbSNP
rs1000572142 1739 dbSNP
rs906119440 1745 dbSNP
rs1045042100 1749 dbSNP
rs1295174568 1758 dbSNP
rs1341179528 1764 dbSNP
rs1196036952 1774 dbSNP
rs950187483 1775 dbSNP
rs1408304904 1809 dbSNP
rs1288648982 1810 dbSNP
rs1449380762 1813 dbSNP
rs1178536638 1816 dbSNP
rs867353733 1821 dbSNP
rs1187201306 1822 dbSNP
rs1253064760 1822 dbSNP
rs1470211021 1822 dbSNP
rs1392445125 1824 dbSNP
rs1475923989 1826 dbSNP
rs1388776597 1829 dbSNP
rs762742913 1829 dbSNP
rs1037050623 1836 dbSNP
rs1173654597 1843 dbSNP
rs940233687 1846 dbSNP
rs1387963522 1854 dbSNP
rs1434337629 1859 dbSNP
rs147260453 1860 dbSNP
rs868321643 1867 dbSNP
rs868008404 1868 dbSNP
rs1056247686 1869 dbSNP
rs867350795 1880 dbSNP
rs1227804867 1884 dbSNP
rs530579034 1892 dbSNP
rs1234743861 1897 dbSNP
rs1260655483 1898 dbSNP
rs563422215 1902 dbSNP
rs1207427087 1914 dbSNP
rs541800713 1917 dbSNP
rs1264394672 1923 dbSNP
rs1038046158 1925 dbSNP
rs149983840 1932 dbSNP
rs911179301 1941 dbSNP
rs1244396559 1942 dbSNP
rs1054748 1945 dbSNP
rs191923374 1951 dbSNP
rs1411352358 1958 dbSNP
rs965170558 1959 dbSNP
rs1318463762 1961 dbSNP
rs1261734579 1966 dbSNP
rs1241610129 1967 dbSNP
rs1382696511 1980 dbSNP
rs1317839864 1982 dbSNP
rs1021015239 1992 dbSNP
rs1306563209 1994 dbSNP
rs1222237059 2005 dbSNP
rs1293486961 2007 dbSNP
rs576745404 2009 dbSNP
rs987769048 2010 dbSNP
rs957914233 2016 dbSNP
rs1352124841 2019 dbSNP
rs988575241 2023 dbSNP
rs558291640 2025 dbSNP
rs956133909 2031 dbSNP
rs1488510569 2038 dbSNP
rs1405253438 2039 dbSNP
rs1265180110 2043 dbSNP
rs757257735 2046 dbSNP
rs139276887 2054 dbSNP
rs1161447009 2073 dbSNP
rs1364452776 2074 dbSNP
rs150822715 2076 dbSNP
rs1454284289 2078 dbSNP
rs1171880896 2090 dbSNP
rs1455159161 2091 dbSNP
rs905007527 2098 dbSNP
rs1399837908 2106 dbSNP
rs376452167 2111 dbSNP
rs141595260 2117 dbSNP
rs970456913 2117 dbSNP
rs1407612554 2118 dbSNP
rs1157948190 2121 dbSNP
rs1308570795 2159 dbSNP
rs751729220 2165 dbSNP
rs895921946 2173 dbSNP
rs1014498098 2176 dbSNP
rs80202510 2181 dbSNP
rs1437415689 2182 dbSNP
rs756539280 2183 dbSNP
rs1350504786 2202 dbSNP
rs1211969916 2205 dbSNP
rs1386601299 2208 dbSNP
rs939993337 2216 dbSNP
rs1444625577 2220 dbSNP
rs888485579 2247 dbSNP
rs1048657748 2251 dbSNP
rs1179137330 2253 dbSNP
rs993630601 2256 dbSNP
rs1432627884 2257 dbSNP
rs148792159 2258 dbSNP
rs146130621 2259 dbSNP
rs1436492530 2268 dbSNP
rs1041234001 2269 dbSNP
rs531736594 2273 dbSNP
rs1214781844 2274 dbSNP
rs538928730 2275 dbSNP
rs187000272 2278 dbSNP
rs913661098 2279 dbSNP
rs1385663777 2283 dbSNP
rs889436444 2300 dbSNP
rs550350457 2301 dbSNP
rs531983354 2302 dbSNP
rs1025295764 2305 dbSNP
rs569753692 2306 dbSNP
rs1297375715 2315 dbSNP
rs957699529 2317 dbSNP
rs1310528719 2320 dbSNP
rs1206929704 2322 dbSNP
rs933923566 2332 dbSNP
rs924974489 2341 dbSNP
rs1208200116 2345 dbSNP
rs922490867 2346 dbSNP
rs1385469232 2348 dbSNP
rs981084922 2352 dbSNP
rs1389339520 2363 dbSNP
rs765521727 2364 dbSNP
rs1025206478 2367 dbSNP
rs1172100384 2373 dbSNP
rs1013425180 2375 dbSNP
rs775520621 2379 dbSNP
rs960366962 2390 dbSNP
rs548008557 2393 dbSNP
rs529819033 2394 dbSNP
rs1015682672 2395 dbSNP
rs1004320923 2408 dbSNP
rs1320412656 2428 dbSNP
rs888434623 2429 dbSNP
rs181922683 2435 dbSNP
rs142922096 2440 dbSNP
rs377129136 2450 dbSNP
rs191159843 2451 dbSNP
rs564884609 2455 dbSNP
rs543201678 2456 dbSNP
rs759885671 2457 dbSNP
rs944212356 2460 dbSNP
rs113811687 2462 dbSNP
rs1247272794 2463 dbSNP
rs1484780793 2471 dbSNP
rs555022994 2473 dbSNP
rs1026526705 2474 dbSNP
rs1419960946 2479 dbSNP
rs1191944623 2482 dbSNP
rs185216408 2485 dbSNP
rs1419418361 2492 dbSNP
rs1292795332 2494 dbSNP
rs1159091793 2497 dbSNP
rs572518169 2500 dbSNP
rs936455261 2504 dbSNP
rs899320546 2509 dbSNP
rs1289857464 2517 dbSNP
rs1378869167 2518 dbSNP
rs924921985 2518 dbSNP
rs144634149 2521 dbSNP
rs879633544 2522 dbSNP
rs969673695 2524 dbSNP
rs1266305252 2532 dbSNP
rs1326950331 2532 dbSNP
rs1277393405 2534 dbSNP
rs1397931052 2538 dbSNP
rs539037396 2539 dbSNP
rs1217825978 2541 dbSNP
rs1303411588 2543 dbSNP
rs1242540007 2544 dbSNP
rs992522101 2547 dbSNP
rs1403897861 2556 dbSNP
rs745959040 2557 dbSNP
rs1259107685 2563 dbSNP
rs1169110711 2566 dbSNP
rs1049869229 2576 dbSNP
rs961852424 2578 dbSNP
rs1157859562 2584 dbSNP
rs1405122045 2595 dbSNP
rs1402998767 2620 dbSNP
rs571961358 2626 dbSNP
rs868136244 2643 dbSNP
rs373641406 2644 dbSNP
rs1433170588 2646 dbSNP
rs754135919 2648 dbSNP
rs1004269940 2651 dbSNP
rs763749929 2653 dbSNP
rs1169088751 2655 dbSNP
rs901138228 2655 dbSNP
rs1027360277 2664 dbSNP
rs1375597094 2666 dbSNP
rs750752734 2668 dbSNP
rs766936298 2670 dbSNP
rs1269992318 2671 dbSNP
rs1199038048 2680 dbSNP
rs1346900605 2682 dbSNP
rs556932554 2682 dbSNP
rs538420117 2683 dbSNP
rs1485816470 2685 dbSNP
rs1180973254 2705 dbSNP
rs1230698136 2706 dbSNP
rs1252838644 2708 dbSNP
rs1008919831 2716 dbSNP
rs865999740 2728 dbSNP
rs1196442641 2743 dbSNP
rs1338767312 2758 dbSNP
rs1257355156 2766 dbSNP
rs1042874458 2769 dbSNP
rs1376414609 2770 dbSNP
rs1429407569 2775 dbSNP
rs1461611252 2781 dbSNP
rs892623378 2788 dbSNP
rs1356386432 2804 dbSNP
rs1216682098 2810 dbSNP
rs1325449992 2817 dbSNP
rs1283656926 2821 dbSNP
rs1305413544 2822 dbSNP
rs1052566345 2826 dbSNP
rs567730845 2828 dbSNP
rs936402986 2831 dbSNP
rs1194901113 2835 dbSNP
rs1270360177 2841 dbSNP
rs549572591 2845 dbSNP
rs1439052794 2863 dbSNP
rs1204680660 2883 dbSNP
rs546949186 2883 dbSNP
rs1467559249 2884 dbSNP
rs1196029683 2888 dbSNP
rs1396095026 2892 dbSNP
rs1449203938 2893 dbSNP
rs1166376590 2903 dbSNP
rs903617473 2922 dbSNP
rs1391475677 2927 dbSNP
rs1045095118 2936 dbSNP
rs915962188 2952 dbSNP
rs1392346576 2957 dbSNP
rs1438649202 2960 dbSNP
rs1327788945 2962 dbSNP
rs1371460368 2966 dbSNP
rs781340467 2967 dbSNP
rs947740655 2967 dbSNP
rs960025630 2971 dbSNP
rs919542020 2976 dbSNP
rs529717779 2982 dbSNP
rs1272048408 2983 dbSNP
rs1466713325 2987 dbSNP
rs1254102319 2990 dbSNP
rs1195352072 2994 dbSNP
rs1191568711 3000 dbSNP
rs1244163517 3003 dbSNP
rs972295861 3007 dbSNP
rs868361264 3010 dbSNP
rs1016858286 3015 dbSNP
rs1463017316 3021 dbSNP
rs1167021250 3030 dbSNP
rs773896304 3033 dbSNP
rs992074339 3035 dbSNP
rs565772089 3040 dbSNP
rs547076225 3042 dbSNP
rs1007693252 3044 dbSNP
rs1471231177 3047 dbSNP
rs1316015256 3053 dbSNP
rs940600603 3062 dbSNP
rs953932193 3063 dbSNP
rs907683716 3064 dbSNP
rs532018707 3073 dbSNP
rs952738409 3074 dbSNP
rs1234527754 3077 dbSNP
rs1273257013 3104 dbSNP
rs1365777868 3109 dbSNP
rs1203874319 3113 dbSNP
rs763558664 3114 dbSNP
rs1447897473 3116 dbSNP
rs1437351513 3130 dbSNP
rs1236378463 3133 dbSNP
rs1476300117 3138 dbSNP
rs1196722160 3140 dbSNP
rs975941988 3143 dbSNP
rs137941983 3151 dbSNP
rs999198264 3153 dbSNP
rs1156697200 3163 dbSNP
rs1342543005 3170 dbSNP
rs1311910051 3171 dbSNP
rs1353242578 3174 dbSNP
rs904409309 3181 dbSNP
rs762521020 3183 dbSNP
rs543337991 3189 dbSNP
rs531521541 3190 dbSNP
rs1008406446 3191 dbSNP
rs1262942263 3193 dbSNP
rs527296016 3208 dbSNP
rs112513346 3218 dbSNP
rs1000998571 3222 dbSNP
rs865785977 3224 dbSNP
rs1334023588 3227 dbSNP
rs904066272 3230 dbSNP
rs775152838 3250 dbSNP
rs947822347 3262 dbSNP
rs769321601 3275 dbSNP
rs1159390724 3284 dbSNP
rs1440223813 3288 dbSNP
rs3192596 3292 dbSNP
rs1373369887 3307 dbSNP
rs1436223367 3309 dbSNP
rs1378585994 3317 dbSNP
rs953565835 3323 dbSNP
rs940548489 3335 dbSNP
rs572401202 3336 dbSNP
rs984740144 3337 dbSNP
rs1446428656 3343 dbSNP
rs1028060034 3360 dbSNP
rs554288568 3367 dbSNP
rs1243689094 3371 dbSNP
rs866751406 3381 dbSNP
rs1336937098 3382 dbSNP
rs997874163 3389 dbSNP
rs930459579 3401 dbSNP
rs1286024320 3411 dbSNP
rs111534556 3412 dbSNP
rs1250905697 3413 dbSNP
rs1031313685 3423 dbSNP
rs547881615 3424 dbSNP
rs1247557444 3426 dbSNP
rs1251331221 3434 dbSNP
rs1458197379 3439 dbSNP
rs578092383 3453 dbSNP
rs1393070383 3455 dbSNP
rs1019588846 3457 dbSNP
rs1284159042 3460 dbSNP
rs1042973961 3464 dbSNP
rs1372202032 3470 dbSNP
rs556618245 3472 dbSNP
rs73598914 3473 dbSNP
rs894298613 3474 dbSNP
rs180942662 3478 dbSNP
rs189426396 3482 dbSNP
rs1295292105 3490 dbSNP
rs1306052113 3493 dbSNP
rs1229846900 3494 dbSNP
rs1419396115 3515 dbSNP
rs1031207993 3529 dbSNP
rs150291047 3530 dbSNP
rs184916599 3532 dbSNP
rs897879586 3539 dbSNP
rs1024234517 3543 dbSNP
rs1260733994 3551 dbSNP
rs1011973332 3557 dbSNP
rs942040340 3565 dbSNP
rs909489774 3569 dbSNP
rs896224760 3570 dbSNP
rs1056107624 3582 dbSNP
rs1004542808 3586 dbSNP
rs886145100 3597 dbSNP
rs114657418 3600 dbSNP
rs930575782 3601 dbSNP
rs923461930 3602 dbSNP
rs1360248935 3604 dbSNP
rs1384165459 3617 dbSNP
rs113813836 3618 dbSNP
rs181476666 3626 dbSNP
rs190226382 3631 dbSNP
rs751035036 3635 dbSNP
rs1193616831 3641 dbSNP
rs1354916667 3643 dbSNP
rs1231588165 3654 dbSNP
rs1275117047 3656 dbSNP
rs1336906257 3671 dbSNP
rs965105100 3674 dbSNP
rs1259952349 3683 dbSNP
rs1283450749 3687 dbSNP
rs1469649671 3688 dbSNP
rs1187912267 3689 dbSNP
rs921758162 3696 dbSNP
rs1031341425 3712 dbSNP
rs1359564185 3717 dbSNP
rs549379091 3732 dbSNP
rs1039298748 3735 dbSNP
rs942761124 3736 dbSNP
rs1288504496 3737 dbSNP
rs1021988111 3742 dbSNP
rs1342076541 3745 dbSNP
rs531461071 3753 dbSNP
rs1271194635 3755 dbSNP
rs1158965109 3757 dbSNP
rs912647273 3759 dbSNP
rs986882606 3760 dbSNP
rs1299172782 3761 dbSNP
rs576539106 3761 dbSNP
rs1355132545 3763 dbSNP
rs1413126872 3765 dbSNP
rs1295250678 3769 dbSNP
rs956705430 3772 dbSNP
rs1228852032 3784 dbSNP
rs778030684 3785 dbSNP
rs979623348 3786 dbSNP
rs116673212 3788 dbSNP
rs1023764247 3798 dbSNP
rs1208251820 3799 dbSNP
rs567410720 3810 dbSNP
rs1472801568 3816 dbSNP
rs1012836556 3818 dbSNP
rs375466179 3829 dbSNP
rs76108913 3840 dbSNP
rs1406496110 3850 dbSNP
rs184476790 3851 dbSNP
rs1004658885 3867 dbSNP
rs1159666284 3878 dbSNP
rs1375195286 3879 dbSNP
rs1433114676 3881 dbSNP
rs886093004 3883 dbSNP
rs1359822663 3884 dbSNP
rs1421585417 3885 dbSNP
rs140404645 3905 dbSNP
rs887768335 3906 dbSNP
rs377072691 3912 dbSNP
rs1309776155 3915 dbSNP
rs1346820675 3934 dbSNP
rs1231630127 3940 dbSNP
rs994741693 3946 dbSNP
rs932250636 3949 dbSNP
rs1203288136 3953 dbSNP
rs923493186 3968 dbSNP
rs976221969 3971 dbSNP
rs1179753927 3979 dbSNP
rs900422026 3982 dbSNP
rs1038833216 3985 dbSNP
rs1452893112 3993 dbSNP
rs1245689391 4005 dbSNP
rs1426215428 4013 dbSNP
rs944532599 4015 dbSNP
rs1218721094 4017 dbSNP
rs1409605193 4018 dbSNP
rs192433394 4023 dbSNP
rs1051112473 4025 dbSNP
rs1448937245 4028 dbSNP
rs1274327794 4029 dbSNP
rs1331875258 4033 dbSNP
rs1218519121 4039 dbSNP
rs935428519 4047 dbSNP
rs977183404 4056 dbSNP
rs968812019 4065 dbSNP
rs1276390135 4067 dbSNP
rs1345323748 4084 dbSNP
rs1285556704 4089 dbSNP
rs563102590 4097 dbSNP
rs755148621 4100 dbSNP
rs1021308671 4110 dbSNP
rs7836186 4111 dbSNP
rs968293492 4112 dbSNP
rs1195970814 4115 dbSNP
rs1247625809 4121 dbSNP
rs1475237288 4127 dbSNP
rs369533490 4132 dbSNP
rs958614320 4133 dbSNP
rs1421782084 4135 dbSNP
rs147841124 4136 dbSNP
rs1355151233 4138 dbSNP
rs916808447 4139 dbSNP
rs1466154169 4143 dbSNP
rs1164285688 4145 dbSNP
rs1393728376 4146 dbSNP
rs766703652 4151 dbSNP
rs1465020477 4152 dbSNP
rs1421265743 4159 dbSNP
rs1002741456 4160 dbSNP
rs897649703 4165 dbSNP
rs1267979730 4174 dbSNP
rs145967867 4175 dbSNP
rs1433466009 4181 dbSNP
rs1424040907 4201 dbSNP
rs1189024923 4213 dbSNP
rs1006326311 4214 dbSNP
rs1238202259 4217 dbSNP
rs887833344 4219 dbSNP
rs1050459068 4220 dbSNP
rs1446745956 4221 dbSNP
rs1191319217 4222 dbSNP
rs1265687945 4225 dbSNP
rs532334808 4228 dbSNP
rs750867849 4230 dbSNP
rs1456798693 4239 dbSNP
rs79815374 4240 dbSNP
rs1474195809 4244 dbSNP
rs1040595028 4250 dbSNP
rs950466507 4251 dbSNP
rs1391190299 4264 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 80223.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgaaagAGCC--UCGAGUCUCGUu 5'
                |:||  |  |||||||| 
Target 5' ---gcaUUGGUUAUAUCAGAGCAc 3'
 		1 - 21
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 80223.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgaaagagccucgAGUCUCGUu 5'
                       |||||||| 
Target 5' --------uuauaUCAGAGCAc 3'
 		1 - 14
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000287263.4 | 3UTR | GCAUUGGUUAUAUCAGAGCACUUUAAUCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000287263.4 | 3UTR | UUAUAUCAGAGCACUUUAAUCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
91 hsa-miR-5691 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT091162 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT242227 TTC9 tetratricopeptide repeat domain 9 2 4
MIRT246192 TXNIP thioredoxin interacting protein 2 2
MIRT251553 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT387267 SOX9 SRY-box 9 2 2
MIRT463486 ZC3H11A zinc finger CCCH-type containing 11A 2 12
MIRT494446 BTG2 BTG anti-proliferation factor 2 2 2
MIRT496478 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT501825 NCOA3 nuclear receptor coactivator 3 2 2
MIRT503072 C6orf120 chromosome 6 open reading frame 120 2 2
MIRT504755 TEP1 telomerase associated protein 1 2 4
MIRT505971 RAB11FIP1 RAB11 family interacting protein 1 2 4
MIRT511868 GOLGA7 golgin A7 2 6
MIRT512900 UBL4A ubiquitin like 4A 2 2
MIRT513048 LYPD6 LY6/PLAUR domain containing 6 2 6
MIRT523772 FAM83D family with sequence similarity 83 member D 2 2
MIRT525126 RPS11 ribosomal protein S11 2 2
MIRT525816 VIMP selenoprotein S 2 10
MIRT531222 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT531729 SLC2A9 solute carrier family 2 member 9 2 2
MIRT536282 LIMA1 LIM domain and actin binding 1 2 2
MIRT537291 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT537724 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT547940 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT554177 SLC35E2B solute carrier family 35 member E2B 2 2
MIRT555015 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT576717 Wars tryptophanyl-tRNA synthetase 2 2
MIRT607484 HEBP2 heme binding protein 2 2 2
MIRT610786 KLK2 kallikrein related peptidase 2 2 2
MIRT611491 ZNF440 zinc finger protein 440 2 2
MIRT613986 DBT dihydrolipoamide branched chain transacylase E2 2 2
MIRT615782 KIAA0319L KIAA0319 like 2 2
MIRT620563 WBSCR27 methyltransferase like 27 2 4
MIRT624157 DGKE diacylglycerol kinase epsilon 2 2
MIRT626088 MKLN1 muskelin 1 2 2
MIRT629481 GSN gelsolin 2 2
MIRT636645 CDK4 cyclin dependent kinase 4 2 2
MIRT638074 HS3ST1 heparan sulfate-glucosamine 3-sulfotransferase 1 2 2
MIRT638442 PLXDC2 plexin domain containing 2 2 2
MIRT641025 KLHL7 kelch like family member 7 2 2
MIRT641539 MOCOS molybdenum cofactor sulfurase 2 2
MIRT643004 ZNF829 zinc finger protein 829 2 2
MIRT643092 NDUFB5 NADH:ubiquinone oxidoreductase subunit B5 2 2
MIRT644979 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT645912 PLXNA3 plexin A3 2 2
MIRT646605 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT648033 FADS6 fatty acid desaturase 6 2 2
MIRT657491 HBEGF heparin binding EGF like growth factor 2 2
MIRT658381 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT659695 CD200 CD200 molecule 2 2
MIRT661276 TEX9 testis expressed 9 2 2
MIRT661348 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT662948 JPH2 junctophilin 2 2 2
MIRT663225 PPY pancreatic polypeptide 2 2
MIRT663280 SPN sialophorin 2 2
MIRT663335 ZNF74 zinc finger protein 74 2 2
MIRT664344 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT664855 TBRG4 transforming growth factor beta regulator 4 2 2
MIRT665484 VPS53 VPS53, GARP complex subunit 2 2
MIRT666428 SH2B3 SH2B adaptor protein 3 2 2
MIRT668162 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT670170 CCDC142 coiled-coil domain containing 142 2 2
MIRT671277 MTO1 mitochondrial tRNA translation optimization 1 2 2
MIRT672284 GP2 glycoprotein 2 2 2
MIRT672435 RAB10 RAB10, member RAS oncogene family 2 2
MIRT672646 SLC25A16 solute carrier family 25 member 16 2 4
MIRT672760 UBE2V2 ubiquitin conjugating enzyme E2 V2 2 2
MIRT672834 AKR7L aldo-keto reductase family 7 like (gene/pseudogene) 2 2
MIRT672841 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT673080 AK1 adenylate kinase 1 2 2
MIRT673148 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT673323 THAP1 THAP domain containing 1 2 2
MIRT673893 DCTN6 dynactin subunit 6 2 2
MIRT674182 PLEKHM3 pleckstrin homology domain containing M3 2 2
MIRT674607 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT674740 SLC16A1 solute carrier family 16 member 1 2 2
MIRT675140 MOGAT1 monoacylglycerol O-acyltransferase 1 2 4
MIRT675194 NKPD1 NTPase KAP family P-loop domain containing 1 2 2
MIRT675886 SNAP29 synaptosome associated protein 29 2 2
MIRT679163 PSMB2 proteasome subunit beta 2 2 2
MIRT680337 ZNF281 zinc finger protein 281 2 2
MIRT706699 GPR155 G protein-coupled receptor 155 2 2
MIRT706911 THAP6 THAP domain containing 6 2 2
MIRT707880 SLC45A4 solute carrier family 45 member 4 2 2
MIRT709097 SEPT4 septin 4 2 2
MIRT709408 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT710845 FAM210A family with sequence similarity 210 member A 2 2
MIRT711358 VPS8 VPS8, CORVET complex subunit 2 2
MIRT718590 SCD5 stearoyl-CoA desaturase 5 2 2
MIRT723649 RPTN repetin 2 2
MIRT724208 NUP205 nucleoporin 205 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-5691 Vemurafenib 42611257 NSC761431 approved sensitive cell line (451Lu)

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