miRTarBase - #MIRT506786


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pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-3p
Sequence 51| AGAAGGCACUAUGAGAUUUAGA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 10 + 51299626 27587585, 28550310, 26028588, 26449202, 26487287, 29165639 MiREDiBase
A-to-I 14 10 + 51299636 29233923 MiREDiBase
A-to-I 20 10 + 51299642 18684997, 26449202, 27587585, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs759219082 5 dbSNP
rs1491224174 9 dbSNP
rs746611214 10 dbSNP
rs367648737 11 dbSNP
rs1359467239 14 dbSNP
rs1442565019 16 dbSNP
Putative Targets

Gene Information
Gene Symbol KLHL15   
Synonyms HEL-S-305
Description kelch like family member 15
Transcript NM_030624   
Expression
Putative miRNA Targets on KLHL15
3'UTR of KLHL15
(miRNA target sites are highlighted)		 
>KLHL15|NM_030624|3'UTR
   1 TGACATCCTCCTCCCTAAAAAAAGAGGCAAACAAAGTATTTGTTTGCACAGAGTAATTAATTAAAACATATAAAGAAAAA
  81 CCTCACCAGTTTTACTATCAAAGCCATTGGTCTAACATTGTAAGAATTTTTCATTCTGTGCTAGCATCCTTTTTTTCTTT
 161 TCAGTGGCCTCAAACTCATGCAATAAGTTAATTCTAAGTGCTAGCTCTTGAAACTACTTCCAGAAGCAGTTGAATAGAAT
 241 GCTCCACTTATCTGGGATATTGATTTTCTGCTTTAAACATTTCTTTCAGATGTTAGCGTAGGAGTCATGTGTCTTCTAAG
 321 AGAAGACCCGATAAGTGTCACTGGATGTGATTTCAGTCTCTGTCTCTATCTGAAACCTTTTTGAAGATTTATTTCAGTGT
 401 ATTTCAGTCTGTTATACTTTTTAGTTTTATTATTTAAAAGTTTAAAACTCTTGACCTTTTTGCATGGCTTTTTGCTGAAA
 481 ATGCAAAAATATAAATTTTCTACAAAATTAACTTTTTATATTCAAAACACTATTTCTAAGCTGCCTTCTCTTATCCGCAT
 561 TGTGTTAGTGAAAGCATATTCATACTCGCATACAACCTATAAATACACAAGGCACATCCCTTTTATGCGTGGTTAGGATT
 641 CTATATTTTTAAGCTAGTGCACTTACTTGCACACACAGTTCGCCATACTTGTTGAATTTTAGATGTAACGTCTTTTCACA
 721 TATTAACATTTTTAGAAAGTTGAAATAACTGGAGTCCTCATTTGCTATCAAAGTAGCCTATCTTCAGTCCATACTGATTC
 801 AGTAATATTTGAACTCCTTATATTTCTGAAACATGTATGGTTATGAAAACTAACACTTTATATTTTATTTTCAAAAGTAA
 881 ATGTTAGTGTTCTTTGTCGATGTATGTCTTTTCTTTTTGAAAATGTTTTTCTTTGCAGTCTGTTTAACGTTACCCTGTTT
 961 TTAGTGAGAATCGGAGTGGTATATGACAAGTTCTGGCCCTGCAGCATGCAAGCACTTTTAAAGAGCATTTAGGTAATACC
1041 AGACTCCTAAATCAAGGCCCCTTAAAAGTAAGTGCAACTCCCATTTTTTACATTCAGTAAGGCTGCTGCATTTGTTATTG
1121 AATGGAAGGTAGAAACTCTTAGAAAATTTGACCTCAGTTTTGACTTAGAGGTAAGAAATAGAATTATAATGTTACTGGTT
1201 TTATCTACTTGTTTATTTTGTACAAAATACCCAGCGACACTAGGGATGTAAGCCCTCAGTTTTTGTTTTATTTACTGAAA
1281 GCTATTAGCATGAAGGATAGTAACCACAAAGTTCAGAATGGATCAAGAATAGCTGTTTAAAAGCATTTATAATAAGTGTT
1361 TTAGGATTAGCTGCACCTTTCAACTCTTTAAATGCAGAGGAAAAAACATAGTTGACAAAGTTAAGCAAGAATAACCTGGG
1441 AGTGGATCATTGAAATTGATGCCATTTGCGCATGAGTAGTCTATATCTGATACAGACTAGATCTATACTGGCAAAACTTG
1521 CCAGATCTTAGAATATTGGTGCAATATTGCAATGCCTTCTATATGGCTGCTGATGTATAAATTTTCTAGTTTCACTTTGT
1601 TTGGTGTTTTTTGTTTTTTTGTTTGTTTGTTTGTTTTTTTGCTGCTGCCACCATTGAACATAAAATGGAAGTGTGAAGTC
1681 ATGGAAATGTGAAGACTTTGGTTTTTGGGGGTTTTTTGGGCAGTTATTAGACATACTATGAGATTAAACCTGATCTTCAA
1761 ACTCCAGAATTGGAGGCATTTGGGTTTAAGAAACCAGGTACATAAGTAGCTTTTGAAAAAACCATTGGCATTGATTTCAA
1841 AAATCAATAATAATCTTATTTTATATATGAGACTTATATTTTCATTAACTAGTCCTGTCATTTACTTACAGTTTCCAAAC
1921 ATGAAATTTGGTATCTTGTTTCCCATGGTAATATGGGTAAAAGTCTTTTTCTACATTTAAAAAATACATTATTTTATTTT
2001 TGAAAGTTAGGAATAAGTTAGCCATTTAATTTTTTTCTACATTAGTTTAGTGGCTTTGTATGTGTGCTATTTTGCTTTAA
2081 AGAAAATAACGTCTTCATTATTTTCCTCATTGATGTCTTTTGCTAGAAAAGACCAAGAAAGAGCCATCAGGCCAGGTATC
2161 CACATCAAAGCCTTTACACTATAGTGGTGGTTCTCTTTAATTGCTTAGATATGACTTCATGACCCTAGTCAGGGTGACAT
2241 CTGGGCAAACATTTGAGTATTCTTGGTCTTCCATTTTAAAGACAGAGGCCAAGATCAAAGTTCATGTTTTGTAAAATTCG
2321 TAAAATCTTAACTTGAACTAACTCTGGGTTCAGCTTTACGTAAGTCACGTCGGACCTGATGTTAGCTGTAATCAGTTTTG
2401 AGCTTTAAGGATAGTTGCTGTTGCTTGGGTTCTGAATGTATGAGAAAACTCCCTGTTTATATGTAGTTCTAATTTAGGTT
2481 ATTTTAAATCCATGATTAACTTACATTCCCTTTTAAAATTATGGTTTTATTGCTGCAAGAGATTTATTTTTGTTATACTA
2561 AACTATGGAAAAGTTTTTCATAGCATTTTTTTCAAGTTTATTTTTTGTGTGCTTCATTTGGAGTTTTTGTTTATATACAT
2641 TGCGCTCAAAAAAGTAGTTTTTTGAAAAATTCAGTAAGATTTGAATCTATACAGTTTAACTGTTATGACCTTTATGCGTG
2721 TTGTTTTCACTTTATATCTCAAATGCCAGAGTTCACAAAAATAGCTGATCTTCATTAATTACATCTTAATTAGAACCATT
2801 TGTTCTCTTCCGTGTCTTTGACCTTCTAAGTTTTGATTTTAAAGAAATTCCTTGCACTACAGCCTTTTCTTAAAATGCAA
2881 GATTCTCACTTTGAAGGTTTTGTGTTGGAAGAAATGCTACTGGTTTTTAAAAAGCAAAGCTTAACTAATAGAATTATTAG
2961 CTTTTCTTGAGACAGCTTTCTGTGTCCTCATTACTCTGCTCTGTGTGAGTGTTACTAGAATTTGTGAAATACTGACTGAG
3041 CCCTTCACTTATCTTTTCTAAAGCAGCACCTTTGGACACCTCATTCTGGGAAGCCTGCTCGAGTCATAGTAAAGGACACA
3121 CGCTTTATGTGGGGAGAAGTGGTAAAAATGGAGTTTTGTCTTAATTACATGAAACTAAGCTTTAAAATATTTTATAACAG
3201 ATTATTTGAGCTGCATAATCTAAACATGTCAAACGTTCAGTGGGACTATTTTTATATATGTATATGTGGGTGTAGGTCAT
3281 AACATTTCAGTTTATAATATAAATTGTTATTTCAGTTTATAAGCTATCTCTCAGAGGAGACTAGCTCTTTTGAGAATTCA
3361 TAATTTAAAGTTTTAGACTGAAGTAAAATGCAACATAGATAATAGTGTAAATCAGATATAATTGAGGGCTATATGGCAGT
3441 AAAACTGCTAGTGCCAGTTTTCTTGTTTGCCTGTTATACATTTTTGATTTTTGTTTTTGTATTCTGAACATTTTGAGAGA
3521 TCATATGTTTGTTCAATTACATTTAGAGTTGGTTTGGGAATAAATATCTTCTAAAAAGAGATTTATCTTAAAAATGGAAG
3601 TCCTAAAAATTAGTTTATCCAGAGTTTATAAAGTCAAATATTCAGTAGGCATAGACTGGAATAGATAAATTCATGGAAAT
3681 CATATCCTTTCAGTACACCGTATAACTTCAATATTACACAAGTAACATTGAGGAGAATGCCATCAGCTTTGTTCTCCCTT
3761 AAATTCTTTGGTTTTCTTTTTACATTTTGGGAACAACTGCATTTAAAATGTTATTAGTCAGTATATAGTAAGGATTAGGT
3841 GTTTGCTTTCTGAAGGAATGGTCCAGTGAGGTGATTGGGAGAGGTTATTTTCTACCTAACTTGTATATGCCCTATACCTC
3921 TTGGGCATACTTTGTCTATAGAAAAATATTTTGACCTTTAGGTACATTTTGGGCCAGTAGTCAAATAATCCTAGGGCCGA
4001 TATAAAAATCTTAGAATAATTTAAGGTTTGCCTTTTATACCTGTTTTGAAAGCCTTTACATTTTTGTCAGGTAATTTTTC
4081 CCAAGCCGTGGATATAATCTATTCAAACATGTTTATGCTATCCATTCTGTTTTTAAATTGAAAAAAATGTTAAAAGTGTT
4161 TATGAAGAAAAGTTTAAATAAAATATTTTTAATCTTTAAAATATAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agauUUAGAGUAUCACGGAAGa 5'
              ||| |:: | ||||||| 
Target 5' gtgcAATATTGCAATGCCTTCt 3'
 1539 - 1560 158.00 -12.20
2 
miRNA  3' agauuUAGAGUAUC-ACGGAAGa 5'
               ||:||  || ||||||| 
Target 5' acactATTTCTAAGCTGCCTTCt 3'
 527 - 549 157.00 -16.50
3 
miRNA  3' agAUUUAGAGUAUCACGGAAGa 5'
            ||::  |||| |||:|||| 
Target 5' cgTAGGAGTCAT-GTGTCTTCt 3'
 297 - 317 147.00 -15.30
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1478228760 4 dbSNP
rs532904531 5 dbSNP
rs182471953 7 dbSNP
rs780961925 8 dbSNP
rs1268538479 23 dbSNP
rs1463640021 24 dbSNP
rs747838167 24 dbSNP
rs778491924 24 dbSNP
rs1187973000 29 dbSNP
rs1242977940 32 dbSNP
rs754728995 34 dbSNP
rs1215457589 36 dbSNP
rs754754581 37 dbSNP
rs746683646 39 dbSNP
rs753681944 39 dbSNP
rs779934606 47 dbSNP
rs1218702502 51 dbSNP
rs931811959 53 dbSNP
rs1406279162 97 dbSNP
rs964399585 111 dbSNP
rs1387060694 113 dbSNP
rs1433763927 124 dbSNP
rs1320626391 143 dbSNP
rs756253697 150 dbSNP
rs1262223525 157 dbSNP
rs1206787966 162 dbSNP
rs1463538734 163 dbSNP
rs1266923077 164 dbSNP
rs752935513 166 dbSNP
rs1325079550 167 dbSNP
rs1272676992 183 dbSNP
rs1445364461 204 dbSNP
rs1283198950 210 dbSNP
rs1379655843 216 dbSNP
rs56242532 220 dbSNP
rs1053454351 251 dbSNP
rs1266209045 270 dbSNP
rs935044093 283 dbSNP
rs755043687 286 dbSNP
rs760808190 297 dbSNP
rs1320741114 298 dbSNP
rs982152918 304 dbSNP
rs751639571 308 dbSNP
rs1185723730 309 dbSNP
rs1237070005 311 dbSNP
rs776227242 318 dbSNP
rs1470971823 320 dbSNP
rs1190474696 326 dbSNP
rs146597679 329 dbSNP
rs1172188538 330 dbSNP
rs958847462 331 dbSNP
rs1026435984 335 dbSNP
rs1386539559 335 dbSNP
rs775777707 341 dbSNP
rs1333156398 355 dbSNP
rs1340671360 358 dbSNP
rs993752787 367 dbSNP
rs185198388 370 dbSNP
rs1286208355 375 dbSNP
rs866991965 381 dbSNP
rs1349586038 397 dbSNP
rs1228932244 405 dbSNP
rs1373425180 411 dbSNP
rs1190335204 414 dbSNP
rs962397280 415 dbSNP
rs1278236198 421 dbSNP
rs1015016184 425 dbSNP
rs1009305911 429 dbSNP
rs1486118385 436 dbSNP
rs1213218186 440 dbSNP
rs890500917 448 dbSNP
rs1472447143 449 dbSNP
rs1366039270 453 dbSNP
rs907473785 453 dbSNP
rs750713748 454 dbSNP
rs1447449941 456 dbSNP
rs1171484733 464 dbSNP
rs1375747266 488 dbSNP
rs1436209980 490 dbSNP
rs1305721777 492 dbSNP
rs1247267339 495 dbSNP
rs1410147902 496 dbSNP
rs1050284889 503 dbSNP
rs996075892 523 dbSNP
rs772691908 532 dbSNP
rs1462229474 540 dbSNP
rs893735570 546 dbSNP
rs150462731 556 dbSNP
rs1348598875 557 dbSNP
rs1236809682 567 dbSNP
rs935188436 587 dbSNP
rs1482963643 592 dbSNP
rs779479346 593 dbSNP
rs3829712 594 dbSNP
rs1253371996 596 dbSNP
rs1046187938 597 dbSNP
rs1198702701 603 dbSNP
rs949057054 607 dbSNP
rs926536598 610 dbSNP
rs1455161815 612 dbSNP
rs916278624 631 dbSNP
rs990498727 643 dbSNP
rs937553371 654 dbSNP
rs1389143942 658 dbSNP
rs920850489 659 dbSNP
rs1364959956 662 dbSNP
rs903170349 669 dbSNP
rs1299665160 673 dbSNP
rs771157051 681 dbSNP
rs775195971 689 dbSNP
rs1386147134 704 dbSNP
rs1326452685 711 dbSNP
rs1371848821 712 dbSNP
rs1455097808 714 dbSNP
rs1443169948 719 dbSNP
rs1295731213 723 dbSNP
rs1341721336 729 dbSNP
rs1042134299 740 dbSNP
rs973944793 745 dbSNP
rs1354601904 756 dbSNP
rs962269579 757 dbSNP
rs1254117586 771 dbSNP
rs923201959 778 dbSNP
rs1186088307 782 dbSNP
rs1247099430 799 dbSNP
rs975852800 801 dbSNP
rs56051542 809 dbSNP
rs5925970 814 dbSNP
rs1166953668 826 dbSNP
rs1165630005 829 dbSNP
rs1463143361 835 dbSNP
rs943207026 835 dbSNP
rs954859473 856 dbSNP
rs1318612512 860 dbSNP
rs1361293978 864 dbSNP
rs1382992096 866 dbSNP
rs1297942461 867 dbSNP
rs1389346294 872 dbSNP
rs1339097578 878 dbSNP
rs1028920414 882 dbSNP
rs774012696 883 dbSNP
rs770946002 888 dbSNP
rs1184107831 895 dbSNP
rs1473760891 896 dbSNP
rs1235241946 897 dbSNP
rs996149981 898 dbSNP
rs1266953429 902 dbSNP
rs754662844 917 dbSNP
rs1187925586 919 dbSNP
rs375474258 920 dbSNP
rs1423070616 931 dbSNP
rs917968188 936 dbSNP
rs1188389666 949 dbSNP
rs3813165 952 dbSNP
rs1202612329 972 dbSNP
rs1247669854 973 dbSNP
rs371078072 978 dbSNP
rs1290902125 985 dbSNP
rs1400293886 988 dbSNP
rs984551404 989 dbSNP
rs1294277122 990 dbSNP
rs951919247 998 dbSNP
rs1248795809 1001 dbSNP
rs918913069 1002 dbSNP
rs902370978 1003 dbSNP
rs1046558833 1004 dbSNP
rs949136760 1023 dbSNP
rs894916525 1039 dbSNP
rs1253948484 1044 dbSNP
rs1013050940 1058 dbSNP
rs1482718658 1058 dbSNP
rs935308581 1059 dbSNP
rs958852303 1060 dbSNP
rs1033207872 1061 dbSNP
rs1181388938 1062 dbSNP
rs1408592100 1062 dbSNP
rs1306356040 1087 dbSNP
rs1161371131 1090 dbSNP
rs1429407311 1091 dbSNP
rs1434352066 1096 dbSNP
rs1000266028 1099 dbSNP
rs1377676577 1106 dbSNP
rs903283960 1114 dbSNP
rs779484710 1117 dbSNP
rs1225030973 1135 dbSNP
rs1298579278 1141 dbSNP
rs930973519 1141 dbSNP
rs1234615697 1149 dbSNP
rs998600765 1153 dbSNP
rs1346941578 1156 dbSNP
rs1233451335 1167 dbSNP
rs1481566917 1171 dbSNP
rs192286750 1175 dbSNP
rs1040263603 1177 dbSNP
rs943325151 1179 dbSNP
rs1407004994 1184 dbSNP
rs747956618 1190 dbSNP
rs1397086885 1191 dbSNP
rs973719790 1207 dbSNP
rs1170175379 1209 dbSNP
rs1355423461 1211 dbSNP
rs940836258 1215 dbSNP
rs1444998894 1222 dbSNP
rs1292256392 1225 dbSNP
rs1411465492 1226 dbSNP
rs1369635975 1230 dbSNP
rs1440971930 1232 dbSNP
rs1305227934 1236 dbSNP
rs781322688 1236 dbSNP
rs755201545 1252 dbSNP
rs1339627291 1258 dbSNP
rs1162597169 1266 dbSNP
rs1213833097 1268 dbSNP
rs868440789 1270 dbSNP
rs1273459194 1284 dbSNP
rs186977914 1290 dbSNP
rs867817403 1292 dbSNP
rs1253404551 1296 dbSNP
rs988056452 1319 dbSNP
rs147687619 1337 dbSNP
rs1029035024 1346 dbSNP
rs1194336955 1356 dbSNP
rs758448054 1359 dbSNP
rs1255195463 1374 dbSNP
rs1270030308 1379 dbSNP
rs1447906255 1390 dbSNP
rs750917646 1395 dbSNP
rs1224162685 1413 dbSNP
rs12686878 1418 dbSNP
rs1420713399 1430 dbSNP
rs1411956760 1431 dbSNP
rs1394345297 1441 dbSNP
rs1461567002 1457 dbSNP
rs1289742023 1467 dbSNP
rs184024392 1469 dbSNP
rs1362321661 1470 dbSNP
rs1429594452 1471 dbSNP
rs1270371820 1472 dbSNP
rs1032657776 1483 dbSNP
rs999480022 1484 dbSNP
rs41309551 1486 dbSNP
rs971055058 1508 dbSNP
rs1024786592 1509 dbSNP
rs764405313 1519 dbSNP
rs191107097 1521 dbSNP
rs1275134332 1535 dbSNP
rs1445317774 1536 dbSNP
rs1409437852 1539 dbSNP
rs1242889125 1544 dbSNP
rs894864266 1549 dbSNP
rs139996628 1561 dbSNP
rs1305205234 1571 dbSNP
rs958967486 1573 dbSNP
rs1438270272 1575 dbSNP
rs1347939280 1578 dbSNP
rs1322782146 1581 dbSNP
rs767221147 1604 dbSNP
rs1385842888 1608 dbSNP
rs759284933 1613 dbSNP
rs868310421 1613 dbSNP
rs1156388680 1616 dbSNP
rs1346592364 1617 dbSNP
rs187961161 1617 dbSNP
rs770538787 1621 dbSNP
rs773962238 1621 dbSNP
rs1355782676 1627 dbSNP
rs1235097154 1633 dbSNP
rs762422544 1634 dbSNP
rs1192599233 1635 dbSNP
rs199680569 1637 dbSNP
rs553362160 1637 dbSNP
rs559424437 1637 dbSNP
rs747916137 1637 dbSNP
rs752643571 1637 dbSNP
rs1487681760 1638 dbSNP
rs768826024 1640 dbSNP
rs868546101 1641 dbSNP
rs967453107 1641 dbSNP
rs1486179770 1642 dbSNP
rs866584505 1642 dbSNP
rs1038343444 1648 dbSNP
rs1362543363 1649 dbSNP
rs183716909 1660 dbSNP
rs998262577 1681 dbSNP
rs908136760 1706 dbSNP
rs1051898864 1711 dbSNP
rs1375864086 1719 dbSNP
rs375947514 1735 dbSNP
rs192234356 1736 dbSNP
rs1007416019 1745 dbSNP
rs371561332 1759 dbSNP
rs922019389 1760 dbSNP
rs746004121 1761 dbSNP
rs1352848582 1777 dbSNP
rs958020849 1783 dbSNP
rs1349112772 1784 dbSNP
rs1213462021 1794 dbSNP
rs1303630539 1795 dbSNP
rs1048859584 1800 dbSNP
rs1437772543 1805 dbSNP
rs202211933 1822 dbSNP
rs73486003 1823 dbSNP
rs754207761 1824 dbSNP
rs918973680 1830 dbSNP
rs1395275055 1831 dbSNP
rs1436432219 1843 dbSNP
rs1165930196 1845 dbSNP
rs1431369677 1847 dbSNP
rs1036519343 1855 dbSNP
rs1391902638 1856 dbSNP
rs949809395 1859 dbSNP
rs916899685 1865 dbSNP
rs775867659 1869 dbSNP
rs978516825 1877 dbSNP
rs1348852978 1878 dbSNP
rs764587494 1885 dbSNP
rs1249978712 1887 dbSNP
rs1456210925 1887 dbSNP
rs1339093488 1902 dbSNP
rs1406201499 1905 dbSNP
rs1275690619 1909 dbSNP
rs1466779467 1911 dbSNP
rs756591544 1911 dbSNP
rs1253309025 1930 dbSNP
rs1177763969 1945 dbSNP
rs751236207 1948 dbSNP
rs1013416448 1954 dbSNP
rs959231107 1957 dbSNP
rs1033410125 1962 dbSNP
rs1169628321 1963 dbSNP
rs759688083 1965 dbSNP
rs3073993 1985 dbSNP
rs772021806 1985 dbSNP
rs79127910 1985 dbSNP
rs866134388 1985 dbSNP
rs1388773595 1987 dbSNP
rs1293635563 2004 dbSNP
rs1326257616 2008 dbSNP
rs1272492287 2022 dbSNP
rs1431135206 2022 dbSNP
rs898249922 2028 dbSNP
rs1333325200 2029 dbSNP
rs762454599 2031 dbSNP
rs1213556503 2037 dbSNP
rs1424900970 2048 dbSNP
rs991171166 2062 dbSNP
rs774668784 2069 dbSNP
rs1004287235 2091 dbSNP
rs886658408 2093 dbSNP
rs1052486854 2119 dbSNP
rs771515313 2120 dbSNP
rs1246660482 2129 dbSNP
rs1208689297 2144 dbSNP
rs749582387 2144 dbSNP
rs1428941947 2146 dbSNP
rs922134480 2150 dbSNP
rs1415320498 2155 dbSNP
rs1474842508 2156 dbSNP
rs1165511642 2157 dbSNP
rs1395338603 2159 dbSNP
rs1039193669 2167 dbSNP
rs1459486323 2180 dbSNP
rs936735187 2181 dbSNP
rs547159791 2182 dbSNP
rs1257871579 2208 dbSNP
rs1383180815 2212 dbSNP
rs868670724 2212 dbSNP
rs1280509105 2218 dbSNP
rs978911572 2223 dbSNP
rs978084848 2224 dbSNP
rs967945724 2254 dbSNP
rs188877530 2271 dbSNP
rs1367133165 2283 dbSNP
rs1295248111 2284 dbSNP
rs1236215770 2288 dbSNP
rs1259851914 2300 dbSNP
rs1434344973 2302 dbSNP
rs917838032 2310 dbSNP
rs1020484062 2319 dbSNP
rs149512801 2320 dbSNP
rs965459138 2322 dbSNP
rs1485193475 2325 dbSNP
rs1188632313 2326 dbSNP
rs959180120 2342 dbSNP
rs1033483831 2348 dbSNP
rs1464220545 2354 dbSNP
rs1334336770 2359 dbSNP
rs139195303 2360 dbSNP
rs1018209940 2368 dbSNP
rs962450910 2369 dbSNP
rs1006861499 2372 dbSNP
rs1431976227 2378 dbSNP
rs1414531258 2382 dbSNP
rs1314067003 2384 dbSNP
rs150810894 2402 dbSNP
rs1389236879 2412 dbSNP
rs757797794 2416 dbSNP
rs1305680561 2424 dbSNP
rs1316943671 2451 dbSNP
rs1003881182 2459 dbSNP
rs1241899299 2471 dbSNP
rs1277720431 2492 dbSNP
rs1346930653 2493 dbSNP
rs889004250 2504 dbSNP
rs749999414 2515 dbSNP
rs552037394 2523 dbSNP
rs1176487307 2544 dbSNP
rs1249952881 2546 dbSNP
rs1027987393 2555 dbSNP
rs1160732603 2556 dbSNP
rs775684221 2561 dbSNP
rs994805675 2565 dbSNP
rs1434561738 2580 dbSNP
rs1174643700 2593 dbSNP
rs1361195980 2596 dbSNP
rs1460946383 2597 dbSNP
rs866614639 2602 dbSNP
rs897646877 2613 dbSNP
rs890811231 2639 dbSNP
rs1051956078 2640 dbSNP
rs997697361 2641 dbSNP
rs949758133 2643 dbSNP
rs1180124253 2644 dbSNP
rs1369767282 2654 dbSNP
rs895580980 2654 dbSNP
rs900781970 2659 dbSNP
rs1280483356 2661 dbSNP
rs772189641 2673 dbSNP
rs1305513976 2675 dbSNP
rs1055434195 2693 dbSNP
rs1235403718 2704 dbSNP
rs1039138764 2706 dbSNP
rs1180584278 2709 dbSNP
rs936990582 2717 dbSNP
rs745905085 2718 dbSNP
rs778882055 2729 dbSNP
rs979414113 2736 dbSNP
rs946346343 2741 dbSNP
rs1170408890 2764 dbSNP
rs1272271412 2768 dbSNP
rs1227556160 2769 dbSNP
rs1355618528 2793 dbSNP
rs1466782569 2801 dbSNP
rs1323317938 2802 dbSNP
rs141140207 2803 dbSNP
rs945378138 2812 dbSNP
rs1276205994 2822 dbSNP
rs1393731107 2828 dbSNP
rs1377833868 2840 dbSNP
rs1308214250 2843 dbSNP
rs1411316778 2844 dbSNP
rs1296296761 2857 dbSNP
rs1319896820 2859 dbSNP
rs138545582 2868 dbSNP
rs753670873 2874 dbSNP
rs1168427298 2875 dbSNP
rs778476592 2878 dbSNP
rs756536527 2880 dbSNP
rs937885215 2887 dbSNP
rs1222647932 2902 dbSNP
rs1248639525 2903 dbSNP
rs1370648480 2904 dbSNP
rs1186278906 2914 dbSNP
rs1420590497 2949 dbSNP
rs1163321797 2955 dbSNP
rs1479089566 2961 dbSNP
rs763920948 2963 dbSNP
rs1416561552 2974 dbSNP
rs1018324457 2982 dbSNP
rs753182056 2986 dbSNP
rs1325165698 2990 dbSNP
rs1343069945 2996 dbSNP
rs985388233 3009 dbSNP
rs1289244797 3012 dbSNP
rs527618947 3015 dbSNP
rs1342072948 3037 dbSNP
rs1231401839 3038 dbSNP
rs952821241 3040 dbSNP
rs765996122 3046 dbSNP
rs1228957528 3050 dbSNP
rs1027021659 3051 dbSNP
rs995143374 3059 dbSNP
rs973865973 3060 dbSNP
rs183019435 3068 dbSNP
rs1489449426 3072 dbSNP
rs1014736559 3086 dbSNP
rs1204094638 3094 dbSNP
rs1015326829 3100 dbSNP
rs1014103708 3101 dbSNP
rs982968457 3114 dbSNP
rs895526356 3121 dbSNP
rs955164093 3122 dbSNP
rs1267089355 3124 dbSNP
rs1362274143 3127 dbSNP
rs1055548052 3129 dbSNP
rs1029260843 3142 dbSNP
rs1355992533 3159 dbSNP
rs1320555386 3169 dbSNP
rs996473961 3172 dbSNP
rs1348574755 3176 dbSNP
rs937139962 3180 dbSNP
rs904172617 3188 dbSNP
rs1356343860 3189 dbSNP
rs900731306 3194 dbSNP
rs1257503949 3196 dbSNP
rs1443514005 3201 dbSNP
rs1042754991 3202 dbSNP
rs1288478253 3215 dbSNP
rs1229853502 3216 dbSNP
rs946269037 3219 dbSNP
rs1469161867 3234 dbSNP
rs1178908421 3235 dbSNP
rs913500007 3250 dbSNP
rs1041164103 3251 dbSNP
rs944213689 3259 dbSNP
rs1375760376 3262 dbSNP
rs911429677 3271 dbSNP
rs1017848032 3276 dbSNP
rs1334109823 3286 dbSNP
rs1441531289 3290 dbSNP
rs1310355864 3298 dbSNP
rs952856617 3306 dbSNP
rs1232293661 3310 dbSNP
rs1348171933 3311 dbSNP
rs1307045596 3315 dbSNP
rs1387660307 3325 dbSNP
rs749905189 3326 dbSNP
rs1178698808 3333 dbSNP
rs1292261218 3333 dbSNP
rs1457886053 3337 dbSNP
rs764621043 3341 dbSNP
rs761361085 3350 dbSNP
rs1192571107 3351 dbSNP
rs962236245 3352 dbSNP
rs561320257 3360 dbSNP
rs1014851767 3365 dbSNP
rs1166131421 3370 dbSNP
rs776534166 3375 dbSNP
rs1042460372 3380 dbSNP
rs1465224089 3381 dbSNP
rs1332143370 3389 dbSNP
rs1402468276 3391 dbSNP
rs945422659 3402 dbSNP
rs755973578 3423 dbSNP
rs1034212062 3428 dbSNP
rs190789376 3432 dbSNP
rs1235878488 3438 dbSNP
rs938001485 3448 dbSNP
rs1268990401 3472 dbSNP
rs368563938 3477 dbSNP
rs1043087831 3478 dbSNP
rs1207961147 3480 dbSNP
rs1009915477 3489 dbSNP
rs974011368 3499 dbSNP
rs941191271 3503 dbSNP
rs1190745686 3507 dbSNP
rs1041280029 3515 dbSNP
rs908343975 3517 dbSNP
rs1229641380 3521 dbSNP
rs1172682680 3522 dbSNP
rs752924056 3523 dbSNP
rs1326489132 3526 dbSNP
rs760396355 3531 dbSNP
rs1293224022 3532 dbSNP
rs944327596 3535 dbSNP
rs1388681780 3541 dbSNP
rs1321199567 3556 dbSNP
rs767802160 3557 dbSNP
rs1316682191 3573 dbSNP
rs911378357 3585 dbSNP
rs955263193 3585 dbSNP
rs1340245045 3587 dbSNP
rs1029377674 3595 dbSNP
rs975043260 3605 dbSNP
rs931359960 3614 dbSNP
rs963721772 3618 dbSNP
rs1299715331 3619 dbSNP
rs1265727668 3627 dbSNP
rs1386701064 3635 dbSNP
rs1389934046 3644 dbSNP
rs1202931878 3649 dbSNP
rs775279437 3651 dbSNP
rs1323152517 3656 dbSNP
rs1195822880 3667 dbSNP
rs1255311269 3679 dbSNP
rs1474299494 3691 dbSNP
rs1164189772 3694 dbSNP
rs1017792480 3699 dbSNP
rs920029733 3700 dbSNP
rs41311497 3711 dbSNP
rs1156992501 3713 dbSNP
rs904116235 3717 dbSNP
rs1479154792 3722 dbSNP
rs1021515468 3732 dbSNP
rs1009740113 3749 dbSNP
rs1400957685 3765 dbSNP
rs1300665419 3769 dbSNP
rs973105078 3779 dbSNP
rs1395903143 3814 dbSNP
rs1312819936 3816 dbSNP
rs1322958349 3817 dbSNP
rs961396426 3843 dbSNP
rs1259761967 3844 dbSNP
rs1354201924 3851 dbSNP
rs896537561 3860 dbSNP
rs1391661597 3875 dbSNP
rs1196405270 3882 dbSNP
rs917954866 3905 dbSNP
rs1485306216 3907 dbSNP
rs774527570 3908 dbSNP
rs1256974169 3910 dbSNP
rs1425605446 3912 dbSNP
rs1179972566 3914 dbSNP
rs1002201310 3922 dbSNP
rs1248519566 3931 dbSNP
rs1379916760 3939 dbSNP
rs6629782 3941 dbSNP
rs1420756744 3948 dbSNP
rs905223551 3952 dbSNP
rs1034163038 3953 dbSNP
rs1466007767 3961 dbSNP
rs1210551759 3976 dbSNP
rs746109002 3979 dbSNP
rs1038386440 3983 dbSNP
rs1463137778 3990 dbSNP
rs1380775668 3993 dbSNP
rs1389144643 3995 dbSNP
rs941251548 3996 dbSNP
rs908457939 3999 dbSNP
rs1047304253 4014 dbSNP
rs1241782877 4015 dbSNP
rs1277961235 4016 dbSNP
rs1200665022 4019 dbSNP
rs968841393 4026 dbSNP
rs933863106 4030 dbSNP
rs1257655482 4038 dbSNP
rs1346767276 4041 dbSNP
rs1484314674 4060 dbSNP
rs6629781 4070 dbSNP
rs922355242 4087 dbSNP
rs1237585363 4089 dbSNP
rs1021379080 4094 dbSNP
rs1180705501 4099 dbSNP
rs1393682428 4099 dbSNP
rs1253886880 4101 dbSNP
rs774678442 4114 dbSNP
rs1010440830 4136 dbSNP
rs891455096 4138 dbSNP
rs975158521 4140 dbSNP
rs1330097785 4148 dbSNP
rs1400342461 4151 dbSNP
rs1040716837 4158 dbSNP
rs1300773569 4159 dbSNP
rs766789719 4161 dbSNP
rs1303397800 4162 dbSNP
rs1305711740 4183 dbSNP
rs1217869719 4201 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 80311.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714646. RNA binding protein: AGO2. Condition:mildMNase ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 80311.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065670. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000328046.8 | 3UTR | AUCUAUACUGGCAAAACUUGCCAGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCUAGUUUCACU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000328046.8 | 3UTR | AUCUAUACUGGCAAAACUUGCCAGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000328046.8 | 3UTR | CGCAUGAGUAGUCUAUAUCUGAUACAGACUAGAUCUAUACUGGCAAAACUUGCCAGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCUAGUUUCACUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000328046.8 | 3UTR | CCUUCUAUAUGGCUGCUGAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM714646
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repA
Location of target site ENST00000328046.8 | 3UTR | AGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCUAGUUUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000328046.8 | 3UTR | AGACUAGAUCUAUACUGGCAAAACUUGCCAGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1065670
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / 4-thiouridine, 3_ML_LG
Location of target site ENST00000328046.8 | 3UTR | AUCUAUACUGGCAAAACUUGCCAGAUCUUAGAAUAUUGGUGCAAUAUUGCAAUGCCUUCUAUAUGGCUGCUGAUGUAUAAAUUUUCUA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
100 hsa-miR-605-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061339 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT061584 BTG2 BTG anti-proliferation factor 2 2 6
MIRT076140 WDR81 WD repeat domain 81 2 2
MIRT079361 CCDC137 coiled-coil domain containing 137 2 2
MIRT079547 VAMP3 vesicle associated membrane protein 3 2 2
MIRT096242 CANX calnexin 2 2
MIRT243877 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT249186 AKIRIN1 akirin 1 2 8
MIRT273604 SP1 Sp1 transcription factor 2 2
MIRT316766 FOXC1 forkhead box C1 2 4
MIRT322410 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT370117 TRIB3 tribbles pseudokinase 3 2 2
MIRT392725 UBN2 ubinuclein 2 2 2
MIRT406910 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT407440 CTDSP1 CTD small phosphatase 1 2 2
MIRT441887 RD3 retinal degeneration 3 2 4
MIRT444979 C15orf52 chromosome 15 open reading frame 52 2 2
MIRT445241 FOXD4 forkhead box D4 2 2
MIRT445500 FOXD4L5 forkhead box D4 like 5 2 2
MIRT445503 FOXD4L4 forkhead box D4 like 4 2 2
MIRT447025 FOXD4L1 forkhead box D4 like 1 2 2
MIRT447743 TMCC3 transmembrane and coiled-coil domain family 3 2 2
MIRT448761 HDX highly divergent homeobox 2 2
MIRT450003 HAX1 HCLS1 associated protein X-1 2 2
MIRT452830 FAM131B family with sequence similarity 131 member B 2 2
MIRT452872 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT453506 ARRB1 arrestin beta 1 2 2
MIRT454169 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT458742 CES2 carboxylesterase 2 2 2
MIRT459166 HSPA6 heat shock protein family A (Hsp70) member 6 2 21
MIRT460246 IL17RB interleukin 17 receptor B 2 4
MIRT460514 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460698 RNF157 ring finger protein 157 2 2
MIRT461481 METTL1 methyltransferase like 1 2 2
MIRT462617 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT463233 ZNF131 zinc finger protein 131 2 2
MIRT465699 TNPO2 transportin 2 2 8
MIRT466304 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT468957 RPS14 ribosomal protein S14 2 6
MIRT469571 RARA retinoic acid receptor alpha 2 2
MIRT469685 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT470800 PMP22 peripheral myelin protein 22 2 2
MIRT471649 PANK2 pantothenate kinase 2 2 4
MIRT471722 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472281 NFIB nuclear factor I B 2 4
MIRT473680 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT475859 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT477326 EPHA2 EPH receptor A2 2 2
MIRT477831 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478572 CTNND1 catenin delta 1 2 4
MIRT479634 CD81 CD81 molecule 2 2
MIRT481950 ANKRD11 ankyrin repeat domain 11 2 2
MIRT483696 ZNF74 zinc finger protein 74 2 6
MIRT488798 MALT1 MALT1 paracaspase 2 2
MIRT489066 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT492533 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT492857 NRARP NOTCH regulated ankyrin repeat protein 2 2
MIRT496793 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT500122 ZNF106 zinc finger protein 106 2 4
MIRT505359 TMEM167A transmembrane protein 167A 2 2
MIRT506786 KLHL15 kelch like family member 15 2 6
MIRT510692 SRM spermidine synthase 2 6
MIRT515841 CEP104 centrosomal protein 104 2 4
MIRT516448 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT528855 PKP1 plakophilin 1 2 2
MIRT533848 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT539025 ATXN7L1 ataxin 7 like 1 2 4
MIRT542872 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT546543 SATB2 SATB homeobox 2 2 2
MIRT554114 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT560569 ZNF460 zinc finger protein 460 2 2
MIRT560796 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562836 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT563109 IFRD2 interferon related developmental regulator 2 2 2
MIRT564177 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT564283 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT564350 USP22 ubiquitin specific peptidase 22 2 2
MIRT565279 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT565338 TMEM104 transmembrane protein 104 2 2
MIRT565905 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT567108 ITGB1 integrin subunit beta 1 2 2
MIRT567601 FANCF Fanconi anemia complementation group F 2 2
MIRT567779 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568075 CENPQ centromere protein Q 2 2
MIRT624304 COL12A1 collagen type XII alpha 1 chain 2 2
MIRT644395 CDKL1 cyclin dependent kinase like 1 2 2
MIRT661547 ZNF674 zinc finger protein 674 2 4
MIRT670949 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT672951 AKAP5 A-kinase anchoring protein 5 2 2
MIRT697426 ZFP36 ZFP36 ring finger protein 2 2
MIRT700793 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT702657 ITGA3 integrin subunit alpha 3 2 2
MIRT708945 FZR1 fizzy and cell division cycle 20 related 1 2 2
MIRT713657 PLCE1 phospholipase C epsilon 1 2 2
MIRT719239 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719951 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT722048 HLA-E major histocompatibility complex, class I, E 2 2
MIRT722201 URM1 ubiquitin related modifier 1 2 2
MIRT724790 C1D C1D nuclear receptor corepressor 2 2
MIRT734347 CYP2B6 cytochrome P450 family 2 subfamily B member 6 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)

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