miRTarBase - #MIRT508545


—
pre-miRNA Information
pre-miRNA hsa-mir-3622b   
Genomic Coordinates chr8: 27701673 - 27701767
Description Homo sapiens miR-3622b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3622b-3p
Sequence 58| UCACCUGAGCUCCCGUGCCUG |78
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1232922758 2 dbSNP
rs530939348 5 dbSNP
rs1439657384 10 dbSNP
rs1157333896 12 dbSNP
rs66683138 14 dbSNP
rs1044808718 15 dbSNP
rs946438979 19 dbSNP
rs551845360 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PARVG   
Synonyms -
Description parvin gamma
Transcript NM_001137605   
Other Transcripts NM_022141   
Expression
Putative miRNA Targets on PARVG
3'UTR of PARVG
(miRNA target sites are highlighted)		 
>PARVG|NM_001137605|3'UTR
   1 CCCTCACTGCCTCCAAAGCCCAGAGCCTGCCTGTCAGCCCAGCTGGAGGGCCCGAGGCTGCAGGGTGTCCTCCCACAGTC
  81 CCGCTGTTTCCTGTGCATTCGTGACCCGCTTCCCTCCCACCCTGTCTCCTGTCTCCATCGTTGGATTATCTTTGAACCCC
 161 CTTGTGTGGATCATTTTGAGCCGCCTGGCCTTGCTCAGTTTATTTTAATAAAAGTATTTCTGGGAGGGATTCTGGGAACT
 241 TGACAGGGTCCTGAGGAGGGCCCTTAAACCTGCAGCCTCCCTCCCATGGGGTGAGTGTGTGTCACATCAGTCTCTCATCT
 321 CTGGGCCCAGGCTAGTGACCGCCCAGAGAGGTGGCATCACTCAGGGCTGGGGACTCTCAGGGACAGGGCCCACAGCCCCA
 401 GACCCCACCTTTTCCAGCCCAGCTCCCCACACCCACCTGCTTCTCACTCGGGAGGATGGGCCCCAGAGTCACCCTCCAGG
 481 GCAGGAGCCCGAATGGCTCCATAGCCATGCCCCCACCCACCGGGAGAAGTGGATTCAGTGACTGTCAAAGCAACCCGGGC
 561 TGTGTCCTGCAGCTGCCCTCGTGAGTTTTGCCCAAAAGTCACAAAGAAGCAATCTTCGTGGTTGATTAGTGGGTTCAGGT
 641 CATCTCCAGTCTGTCCTCGGGAGCTGTGGGTTCCCACTCGCTCCAGTGAGACTTGGCATTTTCTGCACATAAAGAAGAGT
 721 CGTGTGGGAGAATTGCACATAGTCAGTCCAGGGCATCCAGAGTGGGGCAGAGCTGATGGCTGATGGGAACCGGGGAGGAG
 801 GCTGGCGGGGAGGGGTGAGATTGGTGGGGAGGGCTGGGGCTGGCCGGGAGGGGTGGGACTGATGGGGAGGGGTGAGGCTG
 881 GCGGGGAGGGGTGAGGCTGGCGGGGAGGGGTGGGACTGGTGGGGAGGAGTGAGGCTAGTGGGCGGGTGAGGCTGGCGGGG
 961 AGGGGAGGGTTTGTGGGGACGGGTGAGGCTGGCGGGGAGGGGTGAGGCTGGTGGGGAGGGCTGGGGCCTGGTGGGGAGGA
1041 GTGGGACTTGTGGGGAGGAGTGGGACTTGTGGGGAGGGGTGAGGCTGGGGAGAAGGGCAACCACAGCCCCAGGCTGCTGC
1121 TCCTCCCTGGACCCTGAAGAGGCCTCTGGGTCTGGGGTTTTCACAGTTTGACAGCTGAGGCCTTGGGGAGGGGCTTTAGA
1201 TGGGGGTTAGGGGCTAGGTCATCATTGACACCCACTGGGGGCGCCTAGGCAGATGTCCTTCGGGGGAGCAAGATGGGAGC
1281 CAGGGACGCAGTGCCAGGTCAGCCCTGGGAGCTGGTGTCTGGGTGTGAGAAGGCCTTGAGGGGTCTTCCCTTCACCTAGC
1361 CTCCCATCTGCCTGCCCTTCTCAGCTCCCAATTCACAGGGCAAACCCAAGCCCATAAGCGTGTTCCACGTGAGCACTCAG
1441 ATGCACCCCTCTTCATGGATACCCACCCTACTTCCCGGCTGCCTCTGGGAAACGTGCATCCTCCCACACCAGGTACCTGG
1521 AGCCCAGCTCCTTCCACCTGCTCAGGTGCCCCCTCCATTGCGATGCCCCCTCCAGCACCTCAAATCCTCTCCTGGAGCTT
1601 CTGGGGACACAGGCTCAGCCTCTCTCAGCTGGCTTCATCCCAAAAGCCTGAAATCCAGCCCCACTTCCTGGGGCCTTTGA
1681 GTCCTCACTTGCTTGGGCCCCATCCGCTGCAGGCTGGCTCTGCCTGGCTGTTCCACGTCCTCACTCTTGTTCTATTTGAC
1761 AGCAATTAAAAAAAAAGTGACTTATTTAATTACTGTAGCTTTATTGAAAAATAACTTCCCAGTTTGAAGTGTACAATTTG
1841 ATGAGTTTTGACAAATGCATGCAGTCATATAACCACCACCATCGTTATCCAGACATGGGACATTCCCATCACCATGCAAG
1921 TTTCTGCATCTGTCTGCAGCCAGTTCCCTTCTCCCAGCCCCTGGCCCTGGGGACCACTGATCTGTTTTCTGTCACCATCA
2001 TTTAGACTTGTCTAGAATTTCTTATAAACTGTATCCTATGGTAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guccgugcccuCGAGUCCACu 5'
                     ||||||||| 
Target 5' tccttccacctGCTCAGGTGc 3'
 1529 - 1549 150.00 -17.20
2 
miRNA  3' guccGUGCCCUC--GAGUCCACu 5'
              |||| |||  ||||| || 
Target 5' gttcCACGTGAGCACTCAGATGc 3'
 1422 - 1444 135.00 -15.20
3 
miRNA  3' guccgugCCCUCGAGUCCAcu 5'
                 | |:|:||||||  
Target 5' ttgattaGTGGGTTCAGGTca 3'
 622 - 642 134.00 -13.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM479046 1 COSMIC
COSN30480968 41 COSMIC
COSN30526107 41 COSMIC
COSN30560017 44 COSMIC
COSN28877306 55 COSMIC
COSN30536064 55 COSMIC
COSN30112438 61 COSMIC
COSN31502980 71 COSMIC
COSN30150206 81 COSMIC
COSN30179330 83 COSMIC
COSN1262724 96 COSMIC
COSN30538874 114 COSMIC
COSN30192760 125 COSMIC
COSN31499783 143 COSMIC
COSN29152266 207 COSMIC
COSN16027566 659 COSMIC
COSN27408846 723 COSMIC
COSN15193550 1000 COSMIC
COSN2531571 1009 COSMIC
COSN17008006 1277 COSMIC
COSN1262725 1316 COSMIC
COSN9166891 1774 COSMIC
COSN5771581 1817 COSMIC
COSN5993432 1978 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs772704666 5 dbSNP
rs200144612 8 dbSNP
rs780268732 13 dbSNP
rs948966581 16 dbSNP
rs367879219 17 dbSNP
rs768972686 20 dbSNP
rs777028417 22 dbSNP
rs1369395497 25 dbSNP
rs759288871 26 dbSNP
rs1044591520 27 dbSNP
rs1462237149 28 dbSNP
rs1357047092 31 dbSNP
rs1012434954 33 dbSNP
rs1352002073 34 dbSNP
rs769534907 35 dbSNP
rs764947395 38 dbSNP
rs1208974626 41 dbSNP
rs1398592128 43 dbSNP
rs1269568209 45 dbSNP
rs1463261216 46 dbSNP
rs762763058 47 dbSNP
rs770648337 51 dbSNP
rs1456172962 52 dbSNP
rs1025040706 54 dbSNP
rs1441026280 54 dbSNP
rs970839994 55 dbSNP
rs1192936951 62 dbSNP
rs1488650588 68 dbSNP
rs1248224862 77 dbSNP
rs983976184 79 dbSNP
rs907866758 83 dbSNP
rs963731982 84 dbSNP
rs565580675 90 dbSNP
rs1189696957 92 dbSNP
rs62226663 101 dbSNP
rs1433967755 102 dbSNP
rs1370448105 105 dbSNP
rs919855330 109 dbSNP
rs868815830 114 dbSNP
rs1344188789 118 dbSNP
rs1298465532 125 dbSNP
rs541517406 129 dbSNP
rs1392738015 132 dbSNP
rs1029499238 134 dbSNP
rs985260595 136 dbSNP
rs889740082 138 dbSNP
rs912281287 141 dbSNP
rs1016820030 142 dbSNP
rs1443543880 155 dbSNP
rs943797037 159 dbSNP
rs1219094619 161 dbSNP
rs1290667361 165 dbSNP
rs973800701 167 dbSNP
rs1042571755 182 dbSNP
rs1309126080 183 dbSNP
rs765833233 184 dbSNP
rs1372801027 185 dbSNP
rs1294090379 188 dbSNP
rs1434690304 190 dbSNP
rs529032659 198 dbSNP
rs902160021 208 dbSNP
rs1214310327 210 dbSNP
rs936364251 217 dbSNP
rs1298365253 227 dbSNP
rs1293289181 229 dbSNP
rs1401447901 236 dbSNP
rs1311708247 237 dbSNP
rs1466144426 241 dbSNP
rs768732076 242 dbSNP
rs895418931 243 dbSNP
rs139187 244 dbSNP
rs1025139099 245 dbSNP
rs906733675 246 dbSNP
rs1474332183 248 dbSNP
rs1257142049 249 dbSNP
rs1339377687 255 dbSNP
rs1201060665 256 dbSNP
rs778400048 257 dbSNP
rs1275200354 260 dbSNP
rs948850506 280 dbSNP
rs1015450252 282 dbSNP
rs1204457660 284 dbSNP
rs1319279278 287 dbSNP
rs115138314 288 dbSNP
rs1488958168 289 dbSNP
rs577754876 291 dbSNP
rs1311594828 292 dbSNP
rs1396064054 300 dbSNP
rs1026817853 304 dbSNP
rs551236271 313 dbSNP
rs545110042 315 dbSNP
rs985380103 336 dbSNP
rs571220384 341 dbSNP
rs1053180171 342 dbSNP
rs754144210 348 dbSNP
rs1417370477 349 dbSNP
rs1188511526 352 dbSNP
rs146574663 353 dbSNP
rs977857589 354 dbSNP
rs1176755755 361 dbSNP
rs550778121 363 dbSNP
rs371127850 368 dbSNP
rs1404089719 371 dbSNP
rs1212153752 377 dbSNP
rs1164561991 378 dbSNP
rs1264440531 379 dbSNP
rs1023097983 382 dbSNP
rs1341966344 389 dbSNP
rs1350806013 391 dbSNP
rs1445466324 394 dbSNP
rs1377490521 396 dbSNP
rs73888906 399 dbSNP
rs1053452044 405 dbSNP
rs895366474 430 dbSNP
rs1433795458 431 dbSNP
rs948282155 433 dbSNP
rs1158445267 434 dbSNP
rs1192309732 435 dbSNP
rs1468473775 437 dbSNP
rs536791842 438 dbSNP
rs553199549 446 dbSNP
rs1358005689 447 dbSNP
rs566825942 450 dbSNP
rs1005474115 451 dbSNP
rs950713633 461 dbSNP
rs1215792915 464 dbSNP
rs1014985036 467 dbSNP
rs758923468 468 dbSNP
rs1323932322 470 dbSNP
rs1189366240 473 dbSNP
rs1383000236 474 dbSNP
rs899246961 482 dbSNP
rs994760813 483 dbSNP
rs1243885480 491 dbSNP
rs1028945087 492 dbSNP
rs1382237208 496 dbSNP
rs1171931636 499 dbSNP
rs1477972302 503 dbSNP
rs1378771882 505 dbSNP
rs970214919 508 dbSNP
rs953421090 511 dbSNP
rs1259151023 519 dbSNP
rs985327607 520 dbSNP
rs926248659 522 dbSNP
rs1019979046 523 dbSNP
rs539056136 533 dbSNP
rs1157384290 538 dbSNP
rs182113253 547 dbSNP
rs576036063 557 dbSNP
rs978348905 558 dbSNP
rs1235088194 562 dbSNP
rs923675291 568 dbSNP
rs778154492 570 dbSNP
rs747330281 571 dbSNP
rs779170949 578 dbSNP
rs1277735274 581 dbSNP
rs1400837103 591 dbSNP
rs1362737757 594 dbSNP
rs1311126921 596 dbSNP
rs1414002933 610 dbSNP
rs912894758 613 dbSNP
rs989267721 618 dbSNP
rs933603287 619 dbSNP
rs1477925755 630 dbSNP
rs916231177 634 dbSNP
rs889509586 637 dbSNP
rs1208033093 640 dbSNP
rs544477868 642 dbSNP
rs1279155853 652 dbSNP
rs555186989 659 dbSNP
rs1046613483 660 dbSNP
rs1283459055 665 dbSNP
rs141059303 667 dbSNP
rs1257161393 670 dbSNP
rs1219066987 671 dbSNP
rs952492341 677 dbSNP
rs574902008 680 dbSNP
rs1328794184 681 dbSNP
rs1036943893 682 dbSNP
rs1341158888 684 dbSNP
rs542278705 688 dbSNP
rs542662564 691 dbSNP
rs559046316 709 dbSNP
rs1408707000 711 dbSNP
rs878891259 717 dbSNP
rs1187482942 720 dbSNP
rs1238619527 721 dbSNP
rs994881890 722 dbSNP
rs747145359 723 dbSNP
rs1411665770 736 dbSNP
rs889104696 740 dbSNP
rs1008867454 741 dbSNP
rs1024373931 741 dbSNP
rs970097220 759 dbSNP
rs1472073950 760 dbSNP
rs1001748612 768 dbSNP
rs1019505087 774 dbSNP
rs1272365338 776 dbSNP
rs1033587567 779 dbSNP
rs1285996181 781 dbSNP
rs965678756 789 dbSNP
rs999332694 792 dbSNP
rs989468488 793 dbSNP
rs913458876 806 dbSNP
rs1412211252 807 dbSNP
rs1031245156 808 dbSNP
rs1404365800 810 dbSNP
rs1030492505 812 dbSNP
rs1414136540 813 dbSNP
rs954844717 817 dbSNP
rs1289951892 819 dbSNP
rs1286277609 821 dbSNP
rs1205747804 822 dbSNP
rs1459083349 825 dbSNP
rs986267796 826 dbSNP
rs910782664 831 dbSNP
rs1264502355 835 dbSNP
rs1452381598 836 dbSNP
rs936935929 836 dbSNP
rs1349595536 840 dbSNP
rs1486043697 845 dbSNP
rs1195615955 846 dbSNP
rs528046024 847 dbSNP
rs989481208 850 dbSNP
rs1242932168 851 dbSNP
rs1200013830 853 dbSNP
rs1369510405 854 dbSNP
rs913913419 855 dbSNP
rs1486970546 857 dbSNP
rs1203571966 859 dbSNP
rs1251586682 862 dbSNP
rs1483549047 863 dbSNP
rs1253769449 864 dbSNP
rs1379138598 864 dbSNP
rs1417257453 864 dbSNP
rs1158799013 869 dbSNP
rs945476524 869 dbSNP
rs1046949845 874 dbSNP
rs1407159085 876 dbSNP
rs1248601985 879 dbSNP
rs1162879836 880 dbSNP
rs906622998 883 dbSNP
rs1286817299 884 dbSNP
rs938455459 888 dbSNP
rs1310911013 892 dbSNP
rs1055654471 893 dbSNP
rs1370200410 895 dbSNP
rs1268849490 897 dbSNP
rs1397744715 900 dbSNP
rs1359550469 901 dbSNP
rs894383766 902 dbSNP
rs1182097316 903 dbSNP
rs1006575296 907 dbSNP
rs544636892 912 dbSNP
rs1191316370 913 dbSNP
rs564813041 916 dbSNP
rs1264201014 920 dbSNP
rs1195888813 922 dbSNP
rs1482322379 925 dbSNP
rs1255865795 926 dbSNP
rs1211423309 927 dbSNP
rs1314535162 929 dbSNP
rs1256528428 930 dbSNP
rs1218464017 931 dbSNP
rs1339388694 932 dbSNP
rs1278478568 937 dbSNP
rs530879021 938 dbSNP
rs550491854 940 dbSNP
rs9754331 944 dbSNP
rs1301810275 945 dbSNP
rs1466482703 948 dbSNP
rs1360864191 952 dbSNP
rs1464938655 957 dbSNP
rs111352264 958 dbSNP
rs531281375 962 dbSNP
rs546172869 967 dbSNP
rs1436525421 969 dbSNP
rs986236770 971 dbSNP
rs1369717089 972 dbSNP
rs1484513919 975 dbSNP
rs1017754825 980 dbSNP
rs764249273 980 dbSNP
rs1266934123 981 dbSNP
rs13054457 981 dbSNP
rs1229136037 982 dbSNP
rs1311343828 983 dbSNP
rs762669387 985 dbSNP
rs990177124 985 dbSNP
rs1384857693 986 dbSNP
rs13054616 994 dbSNP
rs1445698789 994 dbSNP
rs1304285390 995 dbSNP
rs967077846 999 dbSNP
rs148236501 1000 dbSNP
rs113145417 1002 dbSNP
rs13053775 1003 dbSNP
rs928010385 1004 dbSNP
rs938089933 1006 dbSNP
rs1456556075 1008 dbSNP
rs576236415 1008 dbSNP
rs1055618065 1013 dbSNP
rs915787761 1018 dbSNP
rs1425665390 1020 dbSNP
rs1197995968 1021 dbSNP
rs1265667793 1022 dbSNP
rs1449562256 1023 dbSNP
rs1458647237 1025 dbSNP
rs1197656355 1028 dbSNP
rs1253114252 1031 dbSNP
rs1455139784 1033 dbSNP
rs567413607 1036 dbSNP
rs1487286852 1038 dbSNP
rs1166652120 1041 dbSNP
rs1389555030 1042 dbSNP
rs1360996553 1043 dbSNP
rs1462408801 1043 dbSNP
rs1169481439 1045 dbSNP
rs1388251883 1047 dbSNP
rs1386454838 1050 dbSNP
rs13057947 1052 dbSNP
rs1294345359 1057 dbSNP
rs1373305172 1060 dbSNP
rs1395136970 1062 dbSNP
rs1158191675 1066 dbSNP
rs1440811840 1069 dbSNP
rs1382749314 1071 dbSNP
rs1433064288 1072 dbSNP
rs1432975611 1076 dbSNP
rs957880036 1078 dbSNP
rs942420819 1079 dbSNP
rs1210052754 1086 dbSNP
rs989215403 1096 dbSNP
rs563400977 1097 dbSNP
rs1356039035 1098 dbSNP
rs919756957 1101 dbSNP
rs929803029 1117 dbSNP
rs1281247499 1128 dbSNP
rs916345645 1133 dbSNP
rs1301789239 1134 dbSNP
rs1406990113 1137 dbSNP
rs1358905613 1138 dbSNP
rs896394797 1147 dbSNP
rs1420404739 1151 dbSNP
rs969018481 1152 dbSNP
rs1186174102 1162 dbSNP
rs1171352080 1169 dbSNP
rs1466030437 1175 dbSNP
rs1378570919 1185 dbSNP
rs982185774 1186 dbSNP
rs1202101001 1189 dbSNP
rs1481202802 1190 dbSNP
rs1246860067 1193 dbSNP
rs1429074216 1201 dbSNP
rs928202718 1202 dbSNP
rs940929496 1207 dbSNP
rs1488333113 1213 dbSNP
rs1195192264 1214 dbSNP
rs1198645054 1216 dbSNP
rs1344300373 1218 dbSNP
rs9754424 1222 dbSNP
rs905990931 1226 dbSNP
rs1165364046 1228 dbSNP
rs1277836118 1230 dbSNP
rs1397043239 1232 dbSNP
rs1400631056 1235 dbSNP
rs920747397 1238 dbSNP
rs930844244 1242 dbSNP
rs1455813139 1243 dbSNP
rs1050443370 1244 dbSNP
rs1320028275 1248 dbSNP
rs1362690158 1259 dbSNP
rs889218713 1262 dbSNP
rs1414504679 1263 dbSNP
rs539013040 1265 dbSNP
rs1340258937 1274 dbSNP
rs139188 1277 dbSNP
rs1243337627 1283 dbSNP
rs569563063 1288 dbSNP
rs746068715 1289 dbSNP
rs955607691 1291 dbSNP
rs1205285073 1292 dbSNP
rs547824665 1312 dbSNP
rs1030946978 1315 dbSNP
rs1219474841 1321 dbSNP
rs1341782940 1325 dbSNP
rs554969759 1328 dbSNP
rs910901107 1331 dbSNP
rs1206840658 1334 dbSNP
rs1254068050 1343 dbSNP
rs1474837879 1353 dbSNP
rs963709698 1357 dbSNP
rs1339277400 1358 dbSNP
rs1444950419 1360 dbSNP
rs1400005779 1369 dbSNP
rs1332537995 1372 dbSNP
rs139189 1379 dbSNP
rs919658130 1380 dbSNP
rs1472195475 1381 dbSNP
rs1471745363 1397 dbSNP
rs1311519131 1402 dbSNP
rs1345862408 1407 dbSNP
rs540488345 1415 dbSNP
rs1185335055 1419 dbSNP
rs552632445 1420 dbSNP
rs150369275 1421 dbSNP
rs949295292 1428 dbSNP
rs1044925193 1429 dbSNP
rs969132902 1430 dbSNP
rs544598458 1434 dbSNP
rs1415917851 1435 dbSNP
rs1227749194 1437 dbSNP
rs188043741 1444 dbSNP
rs530432642 1445 dbSNP
rs961763464 1446 dbSNP
rs972715202 1447 dbSNP
rs920859593 1448 dbSNP
rs191023034 1449 dbSNP
rs1317125457 1452 dbSNP
rs1310418097 1463 dbSNP
rs137938963 1466 dbSNP
rs893205000 1470 dbSNP
rs1321179853 1472 dbSNP
rs1404461111 1476 dbSNP
rs910602751 1477 dbSNP
rs944779746 1478 dbSNP
rs1010843109 1486 dbSNP
rs1211445002 1494 dbSNP
rs1020458738 1495 dbSNP
rs1471044124 1512 dbSNP
rs529862708 1513 dbSNP
rs1481910728 1520 dbSNP
rs903169369 1522 dbSNP
rs1176848369 1523 dbSNP
rs1293998651 1526 dbSNP
rs1409057756 1538 dbSNP
rs934691926 1543 dbSNP
rs796100176 1545 dbSNP
rs1310667080 1547 dbSNP
rs1353553209 1547 dbSNP
rs1052327203 1548 dbSNP
rs893729905 1549 dbSNP
rs891267895 1550 dbSNP
rs1421099357 1552 dbSNP
rs1008490055 1557 dbSNP
rs1018514984 1562 dbSNP
rs1345807474 1563 dbSNP
rs1304380271 1564 dbSNP
rs139190 1565 dbSNP
rs1023463823 1566 dbSNP
rs1159765239 1568 dbSNP
rs1402439114 1569 dbSNP
rs1422792931 1570 dbSNP
rs1190445334 1572 dbSNP
rs1315279734 1579 dbSNP
rs905061959 1582 dbSNP
rs1480871709 1590 dbSNP
rs1271342982 1593 dbSNP
rs1191547878 1599 dbSNP
rs1488006069 1602 dbSNP
rs534489846 1606 dbSNP
rs1261765055 1621 dbSNP
rs1218556048 1631 dbSNP
rs1310999500 1642 dbSNP
rs1027175746 1647 dbSNP
rs1369113118 1648 dbSNP
rs951159739 1649 dbSNP
rs183133368 1657 dbSNP
rs553110474 1673 dbSNP
rs1218397287 1674 dbSNP
rs1003683943 1684 dbSNP
rs1470152861 1687 dbSNP
rs1431636521 1688 dbSNP
rs143406267 1706 dbSNP
rs1298587035 1707 dbSNP
rs760736910 1715 dbSNP
rs1262480584 1721 dbSNP
rs1482534792 1735 dbSNP
rs759108590 1738 dbSNP
rs1204638741 1739 dbSNP
rs1234933482 1744 dbSNP
rs1256626396 1749 dbSNP
rs961986652 1754 dbSNP
rs575259033 1757 dbSNP
rs1203638442 1761 dbSNP
rs1233225607 1763 dbSNP
rs1481757268 1764 dbSNP
rs1189656303 1767 dbSNP
rs1216412354 1768 dbSNP
rs926511272 1768 dbSNP
rs937365941 1768 dbSNP
rs971776656 1769 dbSNP
rs1027824677 1776 dbSNP
rs1252457656 1777 dbSNP
rs952306937 1778 dbSNP
rs893246531 1785 dbSNP
rs1453025432 1786 dbSNP
rs1408010516 1788 dbSNP
rs1329128813 1798 dbSNP
rs946161903 1800 dbSNP
rs1388933649 1808 dbSNP
rs147178009 1820 dbSNP
rs910718644 1830 dbSNP
rs1413637795 1841 dbSNP
rs1171619458 1843 dbSNP
rs1463105373 1851 dbSNP
rs944921627 1853 dbSNP
rs138724898 1864 dbSNP
rs1480076937 1866 dbSNP
rs537877296 1868 dbSNP
rs1291360470 1874 dbSNP
rs1205922789 1875 dbSNP
rs1319417153 1882 dbSNP
rs1369625390 1884 dbSNP
rs924736101 1889 dbSNP
rs1246616712 1893 dbSNP
rs934616709 1895 dbSNP
rs548832205 1898 dbSNP
rs139191 1900 dbSNP
rs1362991444 1902 dbSNP
rs1213873319 1913 dbSNP
rs995620545 1915 dbSNP
rs1026641701 1918 dbSNP
rs1456640631 1919 dbSNP
rs1256578144 1924 dbSNP
rs1349368637 1929 dbSNP
rs1273490406 1931 dbSNP
rs946611579 1933 dbSNP
rs542766732 1938 dbSNP
rs1308972655 1947 dbSNP
rs1379023803 1961 dbSNP
rs1178364995 1966 dbSNP
rs1420051425 1968 dbSNP
rs1045024529 1973 dbSNP
rs1178562854 1976 dbSNP
rs1487338556 1979 dbSNP
rs534378721 1981 dbSNP
rs1361455357 1989 dbSNP
rs1272851864 2002 dbSNP
rs1283803611 2003 dbSNP
rs1469072420 2009 dbSNP
rs1195622283 2021 dbSNP
rs1308968745 2022 dbSNP
rs1385278939 2030 dbSNP
rs1003393939 2042 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545215. RNA binding protein: AGO4. Condition:Control ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 64098.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000444313.3 | 3UTR | CUCAGGUGCCCCCUCCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000444313.3 | 3UTR | CUCAGGUGCCCCCUCCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM545215
Method / RBP PAR-CLIP / AGO4
Cell line / Condition HEK293 / Control
Location of target site ENST00000444313.3 | 3UTR | CUCAGGUGCCCCCUCCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000444313.3 | 3UTR | GCUCAGGUGCCCCCUCCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000444313.3 | 3UTR | CUCAGGUGCCCCCUCCAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
THCA -0.276 0.27 -0.321 0.24 7 Click to see details
102 hsa-miR-3622b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT076713 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT080212 PRKACB protein kinase cAMP-activated catalytic subunit beta 2 2
MIRT081398 GTPBP3 GTP binding protein 3, mitochondrial 2 2
MIRT107158 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT254071 BACH1 BTB domain and CNC homolog 1 2 2
MIRT409790 FOXO3 forkhead box O3 2 2
MIRT448679 MAPK9 mitogen-activated protein kinase 9 2 2
MIRT450206 ABHD15 abhydrolase domain containing 15 2 2
MIRT486621 PDK3 pyruvate dehydrogenase kinase 3 2 2
MIRT489267 TTLL1 tubulin tyrosine ligase like 1 2 2
MIRT493117 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 4
MIRT494570 BAK1 BCL2 antagonist/killer 1 2 2
MIRT497395 RALY RALY heterogeneous nuclear ribonucleoprotein 2 2
MIRT504900 CCDC86 coiled-coil domain containing 86 2 2
MIRT505192 USP46 ubiquitin specific peptidase 46 2 4
MIRT506522 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 6
MIRT508162 ABCC5 ATP binding cassette subfamily C member 5 2 8
MIRT508545 PARVG parvin gamma 2 4
MIRT509850 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT510088 PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2 8
MIRT512094 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT515381 RPL7 ribosomal protein L7 2 2
MIRT519176 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT519964 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT522292 NKAP NFKB activating protein 2 2
MIRT523160 HMGB2 high mobility group box 2 2 4
MIRT525314 FANCA Fanconi anemia complementation group A 2 2
MIRT528194 PLEKHM2 pleckstrin homology and RUN domain containing M2 2 2
MIRT532885 ZNF451 zinc finger protein 451 2 2
MIRT538209 CYR61 cysteine rich angiogenic inducer 61 2 2
MIRT539497 ACTN4 actinin alpha 4 2 2
MIRT554600 RRAGC Ras related GTP binding C 2 2
MIRT562444 DCTN6 dynactin subunit 6 2 2
MIRT562748 AOC3 amine oxidase, copper containing 3 2 2
MIRT565798 SEC14L5 SEC14 like lipid binding 5 2 2
MIRT565838 SCML2 Scm polycomb group protein like 2 2 2
MIRT566072 RCC2 regulator of chromosome condensation 2 2 2
MIRT566104 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 2
MIRT572407 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT576198 Vsig2 V-set and immunoglobulin domain containing 2 2 2
MIRT576313 Acbd7 acyl-Coenzyme A binding domain containing 7 2 2
MIRT576651 Mill2 MHC I like leukocyte 2 1 1
MIRT576859 Socs6 suppressor of cytokine signaling 6 2 2
MIRT606819 BICD2 BICD cargo adaptor 2 2 2
MIRT610738 NUDT16 nudix hydrolase 16 2 4
MIRT614798 RORA RAR related orphan receptor A 2 2
MIRT619006 NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 2 2
MIRT619420 NOS1AP nitric oxide synthase 1 adaptor protein 2 2
MIRT620405 MYO1H myosin IH 2 2
MIRT624869 ABHD13 abhydrolase domain containing 13 2 2
MIRT633527 ZFP30 ZFP30 zinc finger protein 2 2
MIRT633927 DNAH9 dynein axonemal heavy chain 9 2 2
MIRT636611 CLIC5 chloride intracellular channel 5 2 2
MIRT640616 MIOX myo-inositol oxygenase 2 2
MIRT642605 C14orf180 chromosome 14 open reading frame 180 2 2
MIRT644624 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT655113 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT658976 DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 2 4
MIRT661495 CHMP1B charged multivesicular body protein 1B 2 2
MIRT662996 TMEM59 transmembrane protein 59 2 2
MIRT663075 SFR1 SWI5 dependent homologous recombination repair protein 1 2 2
MIRT665405 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT666106 SSR1 signal sequence receptor subunit 1 2 2
MIRT669562 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT670070 ZNF783 zinc finger family member 783 2 2
MIRT671192 ZNF891 zinc finger protein 891 2 2
MIRT675361 KLHL26 kelch like family member 26 2 2
MIRT678857 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT679443 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT684163 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT684543 ZNF460 zinc finger protein 460 2 2
MIRT684674 SLC2A11 solute carrier family 2 member 11 2 2
MIRT684971 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT686006 NEK4 NIMA related kinase 4 2 2
MIRT687758 KIAA1328 KIAA1328 2 2
MIRT688961 ATXN3 ataxin 3 2 2
MIRT689409 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT690001 MMP17 matrix metallopeptidase 17 2 2
MIRT690165 ELP3 elongator acetyltransferase complex subunit 3 2 2
MIRT690202 C5orf45 MRN complex interacting protein 2 2
MIRT690477 ZNF33A zinc finger protein 33A 2 2
MIRT690566 MICA MHC class I polypeptide-related sequence A 2 2
MIRT692160 C10orf111 chromosome 10 open reading frame 111 2 2
MIRT693430 PLGLB2 plasminogen-like B2 2 2
MIRT693547 ZNF708 zinc finger protein 708 2 2
MIRT693697 PLGLB1 plasminogen-like B1 2 2
MIRT695006 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT698525 TFRC transferrin receptor 2 2
MIRT699574 SIKE1 suppressor of IKBKE 1 2 2
MIRT703446 FYTTD1 forty-two-three domain containing 1 2 2
MIRT704397 CTSS cathepsin S 2 2
MIRT704485 CPT1A carnitine palmitoyltransferase 1A 2 2
MIRT709822 STPG1 sperm tail PG-rich repeat containing 1 2 2
MIRT710859 COQ7 coenzyme Q7, hydroxylase 2 2
MIRT711893 INSIG2 insulin induced gene 2 2 2
MIRT713796 CPLX2 complexin 2 2 2
MIRT718800 C1GALT1C1 C1GALT1 specific chaperone 1 2 2
MIRT719501 SEC24B SEC24 homolog B, COPII coat complex component 2 2
MIRT719722 PDE6B phosphodiesterase 6B 2 2
MIRT722204 URM1 ubiquitin related modifier 1 2 2
MIRT723523 CLPTM1L CLPTM1 like 2 2
MIRT725471 GRAP2 GRB2-related adaptor protein 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3622b-3p Platinum 23939 sensitive tissue
hsa-miR-3622b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3622b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-3622b-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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