pre-miRNA Information
pre-miRNA hsa-mir-4282   
Genomic Coordinates chr6: 72967687 - 72967753
Description Homo sapiens miR-4282 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4282
Sequence 40| UAAAAUUUGCAUCCAGGA |57
Evidence Experimental
Experiments SOLiD
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN32074657 13 COSMIC
COSN6331413 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1195771339 5 dbSNP
rs755058572 6 dbSNP
rs1245753664 11 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RAN   
Synonyms ARA24, Gsp1, TC4
Description RAN, member RAS oncogene family
Transcript NM_006325   
Expression
Putative miRNA Targets on RAN
3'UTR of RAN
(miRNA target sites are highlighted)
>RAN|NM_006325|3'UTR
   1 GAATGAAGCTGGAGCCCAGCGTCAGAAGTCTAGTTTTATAGGCAGCTGTCCTGTGATGTCAGCGGTGCAGCGTGTGTGCC
  81 ACCTCATTATTATCTAGCTAAGCGGAACATGTGCTTCATCTGTGGGATGCTGAAGGAGATGAGTGGGCTTCGGAGTGAAT
 161 GTGGCAGTTTAAAAAATAACTTCATTGTTTGGACCTGCATATTTAGCTGTTTTGGAACGCAGTTGATTCCTTGAGTTTCA
 241 TATATAAGACTGCTGCAGTCACATCACAATATTCAGTGGTGAAATCTTGTTTGTTACTGTCATTCCCATTCCTTTTCGTT
 321 TAGAATCAGAATAAAGTTGTATTTCAAATATCTAAGCAAGTGAACTCATCCCTTGTTTATAAATAGCATTTGGAAACCAC
 401 TAAAGTAGGGAAGTTTTATGCCATGTTAATATTTGAATTGCCTTGCTTTTATCACTTAATTTGAAATCTATTGGGTTAAT
 481 TTCTCCCTATGTTTATTTTTGTACATTTGAGCCATGTCACACAAACTGATGATGACAGGTCAGCAGTATTCTATTTGGTT
 561 AGAAGGGTTACATGGTGTAAATATTAGTGCAGTTAAGCTAAAGCAGTGTTTGCTCCACCTTCATATTGGCTAGGTAGGGT
 641 CACCTAGGGAAGCACTTGCTCAAAATCTGTGACCTGTCAGAATAAAAATGTGGTTTGTACATATCAAATAGATATTTTAA
 721 GGGTAATATTTTCTTTTATGGCAAAAGTAATCATGTTTTAATGTAGAACCTCAAACAGGATGGAACATCAGTGGATGGCA
 801 GGAGGTTGGGAATTCTTGCTGTTAAAAATAATTACAAATTTTGCACTTTTTTGTTTGAATGTTAGATGCTTAGTGTGAAG
 881 TTGATACGCAAGGAAAATGGTCCATGTTTACCCACAGTTTTCAGGTACTCCTAGACTTTAAAGATGTCTTGAACATTTAA
 961 GTTCTTCAGCAGTTCACACTACACCGTTTTTTTGTTTTTTTTTCCCCCCCGGGAGGGTTTTTTTGTAGGGCAGCACAGCA
1041 GAGCAGGACATGGATGAAATACTAGGAATATGCACAGTGGGGCAGTGTGGGGGCTTCTCAGTAATGGAGAACAGTTGGTG
1121 AAACTTTTTTTTTTTTTTAACTAAGCATTTAATTTATCTTGCATATTTTCCACATTTAAAAATGAATTAGGTCTATTAGG
1201 ATAATTAGGAGTTTGATCCCATCAACACTATTCTTGTAGCAGTTAGGAATCTTGAGCTATTTTTTTCTCATACGATTACT
1281 ATAGTCCAGTTTACCAAAGTTTTCTTTAGATGTCTGATAATCTTGAGATGATTGCTTACCTTAAAAGGTATAGAAAGGAT
1361 CACTTAAATATATGGAAAAATGAAATAAGGGTGAAGCTGAATAAAGTTCTACTTACTGTATTAACTGGCAACAGTTGAGT
1441 TTCTTAAGATCTGAATTGCTGTGTATGTTACGCTGTATTCAGAACCAGTTTCTAACCAGCCTGTGAGATGGGAAGTTTTT
1521 TCCCCATAATTGGGATGAAACCTTTCATTCAGGTATTTTGAATTGAAGGTGTATGTGTTGTTTGTAACCTTGTGGAGATT
1601 GCAAGTGGTGTTGACATTCTGGATCTTCTATGTAACAGTTGAAATTTGGAAGTGACGTCACTTACCTGTCTAACGTGGTG
1681 TGGGAGAGAATTTACAAGTCCTTTATTGAAAGAATAATTGTTGCAAAATATATTGCTTCTACTTTGCCTGGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' aggaccuACGUUUAAAAu 5'
                 | |||||||| 
Target 5' aaataatTACAAATTTTg 3'
826 - 843 147.00 -5.80
2
miRNA  3' agGAC---CUA-CGUUUAAAAu 5'
            |||   ||| | ||:|||| 
Target 5' gcCTGTGAGATGGGAAGTTTTt 3'
1499 - 1520 136.00 -11.20
3
miRNA  3' aggACCUACGUUUAAAAu 5'
             ||| ||:|||| || 
Target 5' acaTGG-TGTAAATATTa 3'
570 - 586 126.00 -7.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN2374866 6 COSMIC
COSN30157913 8 COSMIC
COSN25532860 20 COSMIC
COSN31544867 21 COSMIC
COSN31491181 24 COSMIC
COSN31480496 54 COSMIC
COSN30117294 72 COSMIC
COSN31567112 80 COSMIC
COSN1144903 146 COSMIC
COSN31605058 166 COSMIC
COSN17182155 280 COSMIC
COSN28249913 313 COSMIC
COSN4898471 533 COSMIC
COSN24848272 998 COSMIC
COSN27225365 1139 COSMIC
COSN17937099 1362 COSMIC
COSN30262478 1371 COSMIC
COSN8701489 1372 COSMIC
COSN1563728 1373 COSMIC
COSN8539066 1523 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs760889205 4 dbSNP
rs1157123413 15 dbSNP
rs1338865194 16 dbSNP
rs530404359 17 dbSNP
rs752334135 18 dbSNP
rs758023706 21 dbSNP
rs1368924575 22 dbSNP
rs1162014288 34 dbSNP
rs777288589 37 dbSNP
rs1438175752 41 dbSNP
rs1300536950 42 dbSNP
rs533877653 45 dbSNP
rs1419865659 63 dbSNP
rs553594595 64 dbSNP
rs1432699712 65 dbSNP
rs1047291027 68 dbSNP
rs1200091788 71 dbSNP
rs576384961 73 dbSNP
rs941499334 86 dbSNP
rs1274032899 87 dbSNP
rs539070915 87 dbSNP
rs905288678 90 dbSNP
rs927207471 92 dbSNP
rs540859396 104 dbSNP
rs1056887513 105 dbSNP
rs1293771275 109 dbSNP
rs1366259670 112 dbSNP
rs1443811407 115 dbSNP
rs1354581620 122 dbSNP
rs556007682 125 dbSNP
rs575918707 127 dbSNP
rs989985283 134 dbSNP
rs1330302345 143 dbSNP
rs15220 151 dbSNP
rs915295701 152 dbSNP
rs145363958 153 dbSNP
rs561915085 154 dbSNP
rs1479984841 156 dbSNP
rs1042516618 161 dbSNP
rs901152461 164 dbSNP
rs934037468 166 dbSNP
rs373935763 167 dbSNP
rs1423045138 171 dbSNP
rs113688889 172 dbSNP
rs572184973 179 dbSNP
rs1050403842 180 dbSNP
rs540678970 185 dbSNP
rs1265933973 193 dbSNP
rs1198272430 195 dbSNP
rs760327534 213 dbSNP
rs1469673358 219 dbSNP
rs1265231159 220 dbSNP
rs1224575236 224 dbSNP
rs1215736630 241 dbSNP
rs3803012 245 dbSNP
rs1247562417 246 dbSNP
rs1373457464 250 dbSNP
rs1802299 254 dbSNP
rs1488182303 257 dbSNP
rs1307824132 261 dbSNP
rs1045515 267 dbSNP
rs1189620642 269 dbSNP
rs149187550 270 dbSNP
rs1465402769 273 dbSNP
rs994302523 275 dbSNP
rs768364673 276 dbSNP
rs1024086762 277 dbSNP
rs971441561 278 dbSNP
rs1188551066 287 dbSNP
rs1161237523 289 dbSNP
rs1473172075 298 dbSNP
rs1419548310 299 dbSNP
rs1381014443 301 dbSNP
rs1178184757 305 dbSNP
rs1001226339 306 dbSNP
rs1000657044 307 dbSNP
rs1204516835 309 dbSNP
rs758439895 309 dbSNP
rs1017357235 318 dbSNP
rs1218575452 319 dbSNP
rs1317979735 320 dbSNP
rs1285921998 325 dbSNP
rs562904170 326 dbSNP
rs1410167624 327 dbSNP
rs780831193 329 dbSNP
rs1384335685 337 dbSNP
rs1164995180 347 dbSNP
rs1315359250 349 dbSNP
rs1349011848 352 dbSNP
rs1395046862 353 dbSNP
rs1376726228 354 dbSNP
rs1034228565 372 dbSNP
rs1454249971 374 dbSNP
rs1299325604 376 dbSNP
rs1350570313 379 dbSNP
rs879859489 385 dbSNP
rs990101443 387 dbSNP
rs913068656 395 dbSNP
rs1423407285 401 dbSNP
rs1254518076 404 dbSNP
rs967262760 408 dbSNP
rs950398652 412 dbSNP
rs978570849 418 dbSNP
rs573832933 419 dbSNP
rs1286406669 424 dbSNP
rs1215047126 430 dbSNP
rs1336651284 432 dbSNP
rs908788636 435 dbSNP
rs922725070 442 dbSNP
rs941561503 443 dbSNP
rs542453809 447 dbSNP
rs1319478486 450 dbSNP
rs1297261678 458 dbSNP
rs933964158 467 dbSNP
rs3803013 469 dbSNP
rs2178080 471 dbSNP
rs765738847 473 dbSNP
rs938101396 476 dbSNP
rs1163848310 480 dbSNP
rs1457468670 482 dbSNP
rs941611569 484 dbSNP
rs1056539655 485 dbSNP
rs1478374237 486 dbSNP
rs896513623 488 dbSNP
rs1490966998 490 dbSNP
rs747727309 503 dbSNP
rs184866898 504 dbSNP
rs1038611476 506 dbSNP
rs1042742556 518 dbSNP
rs897300950 520 dbSNP
rs1000708796 522 dbSNP
rs1227650247 526 dbSNP
rs1276010344 527 dbSNP
rs1317097681 527 dbSNP
rs1225279833 530 dbSNP
rs1253987071 545 dbSNP
rs1246731942 546 dbSNP
rs1017409080 547 dbSNP
rs1483442509 548 dbSNP
rs1388627264 551 dbSNP
rs1300141337 554 dbSNP
rs753827710 564 dbSNP
rs1045868071 570 dbSNP
rs906953459 573 dbSNP
rs1030071971 578 dbSNP
rs534133143 584 dbSNP
rs1034008719 587 dbSNP
rs1378770402 601 dbSNP
rs1198741294 603 dbSNP
rs765112334 604 dbSNP
rs752531143 605 dbSNP
rs188504108 607 dbSNP
rs967589204 616 dbSNP
rs1802282 617 dbSNP
rs1456617047 619 dbSNP
rs1205395579 621 dbSNP
rs1345423209 623 dbSNP
rs1274222556 626 dbSNP
rs1230919515 627 dbSNP
rs1329435291 637 dbSNP
rs1309161941 639 dbSNP
rs975961781 644 dbSNP
rs1413535548 645 dbSNP
rs983149169 646 dbSNP
rs570230955 647 dbSNP
rs539183600 648 dbSNP
rs999912001 650 dbSNP
rs985546879 658 dbSNP
rs1403309885 660 dbSNP
rs1306078211 662 dbSNP
rs1357369015 664 dbSNP
rs974305114 666 dbSNP
rs911201477 667 dbSNP
rs1283323047 668 dbSNP
rs1376708848 670 dbSNP
rs1277588318 674 dbSNP
rs1442815857 674 dbSNP
rs1198674958 679 dbSNP
rs1352665670 681 dbSNP
rs938153598 683 dbSNP
rs1241033433 689 dbSNP
rs1307388952 690 dbSNP
rs1376215590 690 dbSNP
rs1454738221 691 dbSNP
rs1802281 692 dbSNP
rs1341459193 694 dbSNP
rs1277067515 700 dbSNP
rs1333850573 702 dbSNP
rs1413121240 704 dbSNP
rs193062112 707 dbSNP
rs185042554 709 dbSNP
rs918863751 710 dbSNP
rs1273090291 715 dbSNP
rs1377900904 722 dbSNP
rs930095610 724 dbSNP
rs1045907454 725 dbSNP
rs1042404663 727 dbSNP
rs1444577970 727 dbSNP
rs1448504788 728 dbSNP
rs1188854574 729 dbSNP
rs1215760537 730 dbSNP
rs925263028 732 dbSNP
rs936614252 738 dbSNP
rs552715444 743 dbSNP
rs1357409042 744 dbSNP
rs866022767 746 dbSNP
rs1446347431 749 dbSNP
rs1342733075 750 dbSNP
rs1299371808 753 dbSNP
rs937072058 757 dbSNP
rs1358084336 762 dbSNP
rs148007139 766 dbSNP
rs1405440276 768 dbSNP
rs892794724 769 dbSNP
rs1051992052 770 dbSNP
rs14035 771 dbSNP
rs1424013828 774 dbSNP
rs1005018320 777 dbSNP
rs1376758509 786 dbSNP
rs572156068 788 dbSNP
rs1333464809 793 dbSNP
rs779944432 796 dbSNP
rs963027395 806 dbSNP
rs997727200 808 dbSNP
rs1289487161 816 dbSNP
rs148438674 823 dbSNP
rs1279168813 824 dbSNP
rs144200421 824 dbSNP
rs1218565192 829 dbSNP
rs1339180876 833 dbSNP
rs540889043 836 dbSNP
rs959851412 846 dbSNP
rs1348759952 847 dbSNP
rs992347179 853 dbSNP
rs1454466412 854 dbSNP
rs1366269809 857 dbSNP
rs55934763 858 dbSNP
rs1400765603 862 dbSNP
rs966837806 863 dbSNP
rs978562696 867 dbSNP
rs1431421958 868 dbSNP
rs1295407080 872 dbSNP
rs1191676532 873 dbSNP
rs925314014 874 dbSNP
rs1219658280 877 dbSNP
rs1459202924 877 dbSNP
rs1258944841 881 dbSNP
rs936666284 884 dbSNP
rs1278594599 885 dbSNP
rs751847846 886 dbSNP
rs774209743 888 dbSNP
rs189889022 889 dbSNP
rs1448348618 891 dbSNP
rs1248250096 892 dbSNP
rs181045207 903 dbSNP
rs1186286632 905 dbSNP
rs962661955 915 dbSNP
rs1176728533 931 dbSNP
rs886255217 932 dbSNP
rs1189610238 935 dbSNP
rs974046600 937 dbSNP
rs1004666323 939 dbSNP
rs1478083366 940 dbSNP
rs1239068691 947 dbSNP
rs748578286 955 dbSNP
rs1171907557 956 dbSNP
rs546346066 965 dbSNP
rs1258077677 967 dbSNP
rs982140997 967 dbSNP
rs370268326 968 dbSNP
rs1387637020 977 dbSNP
rs937522290 979 dbSNP
rs1312187637 980 dbSNP
rs1318809499 983 dbSNP
rs1332882251 984 dbSNP
rs1241751702 986 dbSNP
rs1308123393 987 dbSNP
rs1376957856 987 dbSNP
rs1444053934 987 dbSNP
rs1381087753 990 dbSNP
rs1055525156 991 dbSNP
rs1303141250 993 dbSNP
rs113262657 995 dbSNP
rs1447004457 995 dbSNP
rs183802682 996 dbSNP
rs1421637621 997 dbSNP
rs1380950852 998 dbSNP
rs1158288718 999 dbSNP
rs1274774676 1000 dbSNP
rs946998695 1001 dbSNP
rs1182865487 1002 dbSNP
rs531748213 1004 dbSNP
rs757543828 1004 dbSNP
rs188117949 1006 dbSNP
rs181992645 1007 dbSNP
rs376888636 1011 dbSNP
rs1237510714 1012 dbSNP
rs773002828 1017 dbSNP
rs1312967070 1018 dbSNP
rs1323207225 1018 dbSNP
rs997422437 1018 dbSNP
rs1030691384 1025 dbSNP
rs760345867 1026 dbSNP
rs978179944 1030 dbSNP
rs570742277 1033 dbSNP
rs1464756776 1036 dbSNP
rs1206387072 1037 dbSNP
rs1361253745 1039 dbSNP
rs1297739394 1041 dbSNP
rs1451706505 1050 dbSNP
rs958074600 1052 dbSNP
rs1165718543 1057 dbSNP
rs1423633016 1058 dbSNP
rs1416083788 1061 dbSNP
rs1196482345 1067 dbSNP
rs1488863665 1069 dbSNP
rs974721323 1074 dbSNP
rs1202907521 1080 dbSNP
rs1007365212 1082 dbSNP
rs1463086113 1088 dbSNP
rs1018273891 1091 dbSNP
rs1319727475 1094 dbSNP
rs1279785692 1095 dbSNP
rs1219008763 1097 dbSNP
rs532858871 1098 dbSNP
rs752746087 1105 dbSNP
rs962781659 1107 dbSNP
rs907736821 1113 dbSNP
rs974157361 1115 dbSNP
rs1491478480 1124 dbSNP
rs1392737910 1125 dbSNP
rs1478344031 1125 dbSNP
rs767255011 1125 dbSNP
rs879224237 1125 dbSNP
rs940517707 1125 dbSNP
rs879001022 1138 dbSNP
rs11061205 1139 dbSNP
rs57468969 1139 dbSNP
rs937044594 1139 dbSNP
rs569266219 1140 dbSNP
rs1159857417 1141 dbSNP
rs200884929 1142 dbSNP
rs981708836 1147 dbSNP
rs191874127 1155 dbSNP
rs1157013399 1163 dbSNP
rs937451756 1164 dbSNP
rs182036361 1173 dbSNP
rs991673516 1175 dbSNP
rs186575853 1179 dbSNP
rs1301992091 1187 dbSNP
rs565850819 1190 dbSNP
rs914293142 1192 dbSNP
rs1386276274 1193 dbSNP
rs947104918 1194 dbSNP
rs140698627 1207 dbSNP
rs1329422827 1212 dbSNP
rs1166684826 1214 dbSNP
rs1467976377 1218 dbSNP
rs1378715822 1219 dbSNP
rs1412181676 1220 dbSNP
rs1452012314 1223 dbSNP
rs1239665610 1229 dbSNP
rs1457174294 1231 dbSNP
rs765138110 1231 dbSNP
rs553593587 1238 dbSNP
rs1202115257 1241 dbSNP
rs191431583 1246 dbSNP
rs1025638971 1252 dbSNP
rs1345772318 1260 dbSNP
rs902718652 1260 dbSNP
rs999649199 1260 dbSNP
rs1032437404 1266 dbSNP
rs182668517 1267 dbSNP
rs1327191649 1270 dbSNP
rs763813558 1273 dbSNP
rs1051649516 1274 dbSNP
rs889050866 1276 dbSNP
rs1432362938 1277 dbSNP
rs1381578064 1279 dbSNP
rs1158889597 1280 dbSNP
rs750661462 1282 dbSNP
rs1037485313 1285 dbSNP
rs756245435 1286 dbSNP
rs1189426328 1288 dbSNP
rs1442763978 1289 dbSNP
rs1255433041 1290 dbSNP
rs557961315 1295 dbSNP
rs899027770 1297 dbSNP
rs974782192 1305 dbSNP
rs1029025515 1308 dbSNP
rs1287074770 1318 dbSNP
rs186938343 1329 dbSNP
rs546280440 1335 dbSNP
rs951378399 1336 dbSNP
rs1334113995 1337 dbSNP
rs556697773 1339 dbSNP
rs1003286922 1347 dbSNP
rs1298352679 1348 dbSNP
rs1361907967 1348 dbSNP
rs1418542741 1350 dbSNP
rs114584559 1351 dbSNP
rs973246719 1355 dbSNP
rs1473020146 1359 dbSNP
rs541876969 1360 dbSNP
rs570301609 1362 dbSNP
rs1489192306 1368 dbSNP
rs1217501517 1369 dbSNP
rs189774431 1372 dbSNP
rs937096829 1374 dbSNP
rs1055538311 1383 dbSNP
rs895516178 1383 dbSNP
rs1357517356 1389 dbSNP
rs949747167 1398 dbSNP
rs79305460 1399 dbSNP
rs1231845382 1402 dbSNP
rs1458544420 1403 dbSNP
rs1343002250 1410 dbSNP
rs914722882 1412 dbSNP
rs1342885090 1413 dbSNP
rs999701563 1418 dbSNP
rs564328093 1419 dbSNP
rs893966052 1421 dbSNP
rs977166811 1422 dbSNP
rs1478667997 1423 dbSNP
rs183496105 1428 dbSNP
rs549415963 1430 dbSNP
rs1192803166 1442 dbSNP
rs932978738 1443 dbSNP
rs1240374475 1450 dbSNP
rs1309140027 1454 dbSNP
rs1029490390 1456 dbSNP
rs1272772832 1458 dbSNP
rs1390177908 1462 dbSNP
rs1051882130 1466 dbSNP
rs1341472371 1467 dbSNP
rs987885960 1468 dbSNP
rs1263361853 1470 dbSNP
rs1276039426 1470 dbSNP
rs1157066343 1471 dbSNP
rs779628246 1472 dbSNP
rs910246866 1473 dbSNP
rs943272456 1478 dbSNP
rs1037621888 1487 dbSNP
rs1400699144 1489 dbSNP
rs1169676188 1500 dbSNP
rs527988310 1501 dbSNP
rs898995224 1509 dbSNP
rs556247591 1510 dbSNP
rs1427179534 1513 dbSNP
rs758845498 1517 dbSNP
rs920454200 1522 dbSNP
rs1478386414 1524 dbSNP
rs1047101492 1526 dbSNP
rs887207805 1527 dbSNP
rs1191936052 1528 dbSNP
rs1459384947 1536 dbSNP
rs916987077 1544 dbSNP
rs1273811755 1545 dbSNP
rs142015687 1548 dbSNP
rs1202112637 1561 dbSNP
rs548686612 1562 dbSNP
rs1256547822 1563 dbSNP
rs935616656 1567 dbSNP
rs1423054500 1574 dbSNP
rs1300835905 1575 dbSNP
rs1035677593 1579 dbSNP
rs1377372151 1581 dbSNP
rs958716722 1582 dbSNP
rs1297463154 1585 dbSNP
rs894019138 1590 dbSNP
rs1439740731 1593 dbSNP
rs1360878913 1594 dbSNP
rs1187082242 1597 dbSNP
rs1383663303 1601 dbSNP
rs1013168907 1603 dbSNP
rs890549048 1614 dbSNP
rs1441703208 1615 dbSNP
rs565697210 1616 dbSNP
rs1021895457 1622 dbSNP
rs531573510 1624 dbSNP
rs534609554 1627 dbSNP
rs962025730 1630 dbSNP
rs189136681 1631 dbSNP
rs571422068 1641 dbSNP
rs1027569980 1647 dbSNP
rs1305129709 1653 dbSNP
rs958570257 1656 dbSNP
rs1241680868 1657 dbSNP
rs537265010 1657 dbSNP
rs991738599 1658 dbSNP
rs751874743 1660 dbSNP
rs764199731 1660 dbSNP
rs547640958 1662 dbSNP
rs1395849505 1666 dbSNP
rs1303377176 1667 dbSNP
rs924356963 1668 dbSNP
rs1312456913 1671 dbSNP
rs954600368 1671 dbSNP
rs987263309 1672 dbSNP
rs1421576517 1674 dbSNP
rs1158606774 1675 dbSNP
rs76249959 1675 dbSNP
rs924316805 1678 dbSNP
rs576445988 1683 dbSNP
rs541847334 1685 dbSNP
rs750854157 1686 dbSNP
rs1256012842 1689 dbSNP
rs1218229967 1690 dbSNP
rs1054012327 1695 dbSNP
rs542339094 1698 dbSNP
rs1213148912 1702 dbSNP
rs1296144891 1702 dbSNP
rs1323295361 1709 dbSNP
rs973259400 1715 dbSNP
rs1232450508 1720 dbSNP
rs138621627 1724 dbSNP
rs1401967811 1725 dbSNP
rs1385698587 1731 dbSNP
rs572441701 1732 dbSNP
rs541284060 1733 dbSNP
rs1048032887 1738 dbSNP
rs890610552 1742 dbSNP
rs776326417 1743 dbSNP
rs564439898 1747 dbSNP
rs1461233299 1753 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545212. RNA binding protein: AGO1. Condition:Control PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 5901.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 5901.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 5901.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine "PAR-CLIP data was present in GSM1065669. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 5 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760632. RNA binding protein: AGO2. Condition:AGO-CLIP-22RV1_C ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545212
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / Control
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000543796.1 | 3UTR | UUCUUGCUGUUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000543796.1 | 3UTR | AAAAAUAAUUACAAAUUUUGCACUUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1065669
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_8
Location of target site ENST00000543796.1 | 3UTR | UUAAAAAUAAUUACAAAUUUUGCACUUUUUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
280 hsa-miR-4282 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057628 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT060732 RPS3 ribosomal protein S3 2 2
MIRT063371 ETNK1 ethanolamine kinase 1 2 2
MIRT066257 LRIG3 leucine rich repeats and immunoglobulin like domains 3 2 4
MIRT070774 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT070871 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT078056 PCTP phosphatidylcholine transfer protein 2 2
MIRT078408 DCAF7 DDB1 and CUL4 associated factor 7 2 4
MIRT084059 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT093537 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096072 SFXN1 sideroflexin 1 2 2
MIRT098316 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT100493 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT102254 HBP1 HMG-box transcription factor 1 2 4
MIRT105318 VPS37A VPS37A, ESCRT-I subunit 2 2
MIRT114143 MZT1 mitotic spindle organizing protein 1 2 4
MIRT114873 DICER1 dicer 1, ribonuclease III 2 2
MIRT134683 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT137640 RCOR1 REST corepressor 1 2 2
MIRT155449 CCNT2 cyclin T2 2 4
MIRT165656 DCTN4 dynactin subunit 4 2 2
MIRT177570 CSTF2T cleavage stimulation factor subunit 2 tau variant 2 4
MIRT188514 E2F7 E2F transcription factor 7 2 10
MIRT193019 TMOD3 tropomodulin 3 2 4
MIRT195823 GADD45A growth arrest and DNA damage inducible alpha 2 2
MIRT195885 DEPDC1 DEP domain containing 1 2 6
MIRT206029 NUP50 nucleoporin 50 2 6
MIRT212148 CLCN3 chloride voltage-gated channel 3 2 2
MIRT213999 DCP2 decapping mRNA 2 2 2
MIRT214650 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT221568 CBX3 chromobox 3 2 2
MIRT224544 ZNF623 zinc finger protein 623 2 2
MIRT227654 SET SET nuclear proto-oncogene 2 2
MIRT229992 CHIC1 cysteine rich hydrophobic domain 1 2 2
MIRT238968 QKI QKI, KH domain containing RNA binding 2 2
MIRT239825 ACTB actin beta 2 2
MIRT241084 ZXDA zinc finger, X-linked, duplicated A 2 4
MIRT244852 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT264534 TARDBP TAR DNA binding protein 2 2
MIRT271438 SKI SKI proto-oncogene 2 2
MIRT271597 ENAH ENAH, actin regulator 2 2
MIRT294332 ZNF264 zinc finger protein 264 2 2
MIRT296341 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT301715 TEF TEF, PAR bZIP transcription factor 2 2
MIRT308549 ZNF654 zinc finger protein 654 2 2
MIRT313866 DEPDC1B DEP domain containing 1B 2 2
MIRT315529 MARCKS myristoylated alanine rich protein kinase C substrate 2 2
MIRT321066 RABGEF1 RAB guanine nucleotide exchange factor 1 2 2
MIRT343777 NUTF2 nuclear transport factor 2 2 2
MIRT359109 MAP1B microtubule associated protein 1B 2 2
MIRT397393 GOLGA3 golgin A3 2 4
MIRT400822 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT442171 DSEL dermatan sulfate epimerase-like 2 2
MIRT442777 JAG1 jagged 1 2 2
MIRT442862 SCARF1 scavenger receptor class F member 1 2 4
MIRT442919 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT444567 TRA2B transformer 2 beta homolog 2 2
MIRT444718 CMSS1 cms1 ribosomal small subunit homolog (yeast) 2 2
MIRT445018 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT445853 LRRC1 leucine rich repeat containing 1 2 2
MIRT446242 HELZ helicase with zinc finger 2 2
MIRT446542 GOLGA8B golgin A8 family member B 2 2
MIRT446643 SPTY2D1 SPT2 chromatin protein domain containing 1 2 2
MIRT446948 ZMAT3 zinc finger matrin-type 3 2 4
MIRT447061 KCNAB1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 2 2
MIRT447327 ZSCAN21 zinc finger and SCAN domain containing 21 2 2
MIRT447995 CDX1 caudal type homeobox 1 2 2
MIRT448543 RHEBP1 RHEB pseudogene 1 2 6
MIRT448752 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT448772 GOLGA8A golgin A8 family member A 2 2
MIRT449342 WDR26 WD repeat domain 26 2 2
MIRT450011 SLC16A6 solute carrier family 16 member 6 2 4
MIRT450229 PCNX pecanex homolog 1 2 2
MIRT450340 MRPL17 mitochondrial ribosomal protein L17 2 4
MIRT450381 MSI2 musashi RNA binding protein 2 2 2
MIRT450759 PGGT1B protein geranylgeranyltransferase type I subunit beta 2 2
MIRT450809 NRCAM neuronal cell adhesion molecule 2 2
MIRT450947 ATAD2 ATPase family, AAA domain containing 2 2 2
MIRT459095 CCPG1 cell cycle progression 1 2 2
MIRT462428 TWISTNB TWIST neighbor 2 2
MIRT465200 TROVE2 TROVE domain family member 2 2 4
MIRT467382 SON SON DNA binding protein 2 4
MIRT468546 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT471506 PDE4D phosphodiesterase 4D 2 2
MIRT471981 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT474478 KLHL11 kelch like family member 11 2 8
MIRT475011 KANSL1 KAT8 regulatory NSL complex subunit 1 2 8
MIRT480341 C5orf51 chromosome 5 open reading frame 51 2 2
MIRT482696 TEX9 testis expressed 9 2 6
MIRT483462 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 6
MIRT485623 FAM217B family with sequence similarity 217 member B 2 2
MIRT485714 CASP16 caspase 16, pseudogene 2 8
MIRT486279 SEC23A Sec23 homolog A, coat complex II component 2 2
MIRT491000 PEBP1 phosphatidylethanolamine binding protein 1 2 4
MIRT492594 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT493365 KIF5B kinesin family member 5B 2 2
MIRT494316 CDKN1B cyclin dependent kinase inhibitor 1B 2 2
MIRT495208 EDN3 endothelin 3 2 2
MIRT497011 TCF15 transcription factor 15 2 2
MIRT498512 FRK fyn related Src family tyrosine kinase 2 2
MIRT498778 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT501045 SMG1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase 2 6
MIRT502939 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504806 VHL von Hippel-Lindau tumor suppressor 2 6
MIRT505656 SHMT1 serine hydroxymethyltransferase 1 2 6
MIRT505964 RAB5C RAB5C, member RAS oncogene family 2 6
MIRT506322 OTUD4 OTU deubiquitinase 4 2 4
MIRT506803 KLHL15 kelch like family member 15 2 6
MIRT506917 KBTBD8 kelch repeat and BTB domain containing 8 2 4
MIRT507400 EMC7 ER membrane protein complex subunit 7 2 8
MIRT507471 EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 2 6
MIRT508058 ATP13A3 ATPase 13A3 2 4
MIRT508135 AMD1 adenosylmethionine decarboxylase 1 2 2
MIRT509895 RPS23 ribosomal protein S23 2 4
MIRT510881 RAN RAN, member RAS oncogene family 2 8
MIRT513766 PEX5L peroxisomal biogenesis factor 5 like 2 4
MIRT516898 COPS8 COP9 signalosome subunit 8 2 2
MIRT518703 TIMD4 T-cell immunoglobulin and mucin domain containing 4 2 4
MIRT520429 TTPAL alpha tocopherol transfer protein like 2 6
MIRT521843 PNISR PNN interacting serine and arginine rich protein 2 4
MIRT522116 NUDT3 nudix hydrolase 3 2 4
MIRT525467 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT525583 MTRNR2L7 MT-RNR2-like 7 2 2
MIRT525906 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT526072 C11orf54 chromosome 11 open reading frame 54 2 2
MIRT526232 MTRNR2L5 MT-RNR2-like 5 2 4
MIRT526455 FAM71F2 family with sequence similarity 71 member F2 2 4
MIRT526515 POU5F1B POU class 5 homeobox 1B 2 2
MIRT528032 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT528422 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT528995 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 2 4
MIRT529311 ATRNL1 attractin like 1 2 2
MIRT529376 SKP1 S-phase kinase associated protein 1 2 4
MIRT530015 SRRM1 serine and arginine repetitive matrix 1 2 2
MIRT530089 FMN2 formin 2 2 2
MIRT530942 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2 2
MIRT531229 HIST1H2BD histone cluster 1 H2B family member d 2 2
MIRT533088 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT533299 USP46 ubiquitin specific peptidase 46 2 2
MIRT533318 UNKL unkempt family like zinc finger 2 2
MIRT533721 TMEM30A transmembrane protein 30A 2 2
MIRT534096 AZF1 azoospermia factor 1 2 2
MIRT534188 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534493 SAR1B secretion associated Ras related GTPase 1B 2 2
MIRT536077 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT536242 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT537524 FAM104A family with sequence similarity 104 member A 2 2
MIRT538088 DGKH diacylglycerol kinase eta 2 2
MIRT538475 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT538853 BTG1 BTG anti-proliferation factor 1 2 4
MIRT539075 GDNF glial cell derived neurotrophic factor 2 2
MIRT539480 ACVR2B activin A receptor type 2B 2 4
MIRT540210 ARHGAP18 Rho GTPase activating protein 18 2 2
MIRT541940 TSPAN2 tetraspanin 2 2 2
MIRT543812 COCH cochlin 2 2
MIRT545120 PDZRN4 PDZ domain containing ring finger 4 2 2
MIRT545571 GIMAP4 GTPase, IMAP family member 4 2 2
MIRT545989 XKR4 XK related 4 2 2
MIRT547213 PANK3 pantothenate kinase 3 2 4
MIRT547740 KIAA1468 KIAA1468 2 2
MIRT548022 GRB2 growth factor receptor bound protein 2 2 4
MIRT548032 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548102 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 4
MIRT548217 FKBP1A FK506 binding protein 1A 2 2
MIRT548588 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT548953 CDC27 cell division cycle 27 2 2
MIRT549072 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT550368 INCENP inner centromere protein 2 6
MIRT550546 MYZAP myocardial zonula adherens protein 2 2
MIRT551491 TMEM192 transmembrane protein 192 2 4
MIRT553078 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT554104 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT555127 PTPRG protein tyrosine phosphatase, receptor type G 2 2
MIRT555477 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT555978 NPTN neuroplastin 2 2
MIRT557011 HPRT1 hypoxanthine phosphoribosyltransferase 1 2 2
MIRT557706 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT558333 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT558488 DBN1 drebrin 1 2 2
MIRT559942 ZNF567 zinc finger protein 567 2 2
MIRT561127 ATP2B1 ATPase plasma membrane Ca2+ transporting 1 2 2
MIRT561791 PAWR pro-apoptotic WT1 regulator 2 2
MIRT562438 EEF2 eukaryotic translation elongation factor 2 2 2
MIRT563102 PABPC4L poly(A) binding protein cytoplasmic 4 like 2 2
MIRT563212 ZNF813 zinc finger protein 813 2 2
MIRT563426 KIF3A kinesin family member 3A 2 2
MIRT563473 SPIN4 spindlin family member 4 2 2
MIRT564015 HSPA4 heat shock protein family A (Hsp70) member 4 2 4
MIRT564117 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT564223 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT564503 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 2 2
MIRT564515 DUSP3 dual specificity phosphatase 3 2 2
MIRT564811 ZBTB21 zinc finger and BTB domain containing 21 2 2
MIRT565265 TPD52 tumor protein D52 2 2
MIRT566012 RHOB ras homolog family member B 2 2
MIRT566216 PTMA prothymosin, alpha 2 2
MIRT566638 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT566821 MAPK8 mitogen-activated protein kinase 8 2 2
MIRT566948 LEPROT leptin receptor overlapping transcript 2 2
MIRT567290 HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 2 2
MIRT567895 CSTF2 cleavage stimulation factor subunit 2 2 2
MIRT568731 MTRNR2L3 MT-RNR2-like 3 2 2
MIRT571263 ZNF239 zinc finger protein 239 2 2
MIRT572593 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 2 2
MIRT573827 TGOLN2 trans-golgi network protein 2 2 2
MIRT576391 Fhl2 four and a half LIM domains 2 2 2
MIRT609901 SMS spermine synthase 2 2
MIRT613710 ELMSAN1 ELM2 and Myb/SANT domain containing 1 2 2
MIRT614406 ADAT1 adenosine deaminase, tRNA specific 1 2 2
MIRT615042 DCX doublecortin 2 2
MIRT617514 C5orf45 MRN complex interacting protein 2 2
MIRT619476 PRDM10 PR/SET domain 10 2 2
MIRT620349 TLN1 talin 1 2 2
MIRT620910 PLA2G7 phospholipase A2 group VII 2 2
MIRT622131 SP4 Sp4 transcription factor 2 2
MIRT622955 OTUD7B OTU deubiquitinase 7B 2 2
MIRT623351 MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 2 2
MIRT623619 INTU inturned planar cell polarity protein 2 2
MIRT624409 CCDC171 coiled-coil domain containing 171 2 2
MIRT625171 CCS copper chaperone for superoxide dismutase 2 2
MIRT625685 RPP40 ribonuclease P/MRP subunit p40 2 2
MIRT625875 ALDH18A1 aldehyde dehydrogenase 18 family member A1 2 2
MIRT626002 FAM107A family with sequence similarity 107 member A 2 2
MIRT626872 HRH4 histamine receptor H4 2 4
MIRT628220 FKBP9 FK506 binding protein 9 2 2
MIRT628265 DIO2 iodothyronine deiodinase 2 2 2
MIRT628402 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT630564 C3orf36 chromosome 3 open reading frame 36 2 4
MIRT631577 RASSF9 Ras association domain family member 9 2 2
MIRT635730 CCDC58 coiled-coil domain containing 58 2 2
MIRT636224 SLC8A1 solute carrier family 8 member A1 2 2
MIRT636613 CLIC5 chloride intracellular channel 5 2 2
MIRT638899 CDK9 cyclin dependent kinase 9 2 2
MIRT640167 ATXN7L1 ataxin 7 like 1 2 2
MIRT642070 GTDC1 glycosyltransferase like domain containing 1 2 2
MIRT643034 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 2 2
MIRT644572 SPOP speckle type BTB/POZ protein 2 2
MIRT644954 IFNB1 interferon beta 1 2 2
MIRT645948 TTF2 transcription termination factor 2 2 2
MIRT646440 XRCC2 X-ray repair cross complementing 2 2 2
MIRT647896 EPN2 epsin 2 2 2
MIRT648276 ZNF582 zinc finger protein 582 2 2
MIRT649381 NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2 2
MIRT650254 CD68 CD68 molecule 2 2
MIRT650333 ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) 2 2
MIRT651707 VMP1 vacuole membrane protein 1 2 2
MIRT651774 VASP vasodilator stimulated phosphoprotein 2 2
MIRT653144 SRPK2 SRSF protein kinase 2 2 2
MIRT654112 RPS6KA5 ribosomal protein S6 kinase A5 2 2
MIRT654161 RORB RAR related orphan receptor B 2 2
MIRT655716 MLF2 myeloid leukemia factor 2 2 2
MIRT657476 HDAC4 histone deacetylase 4 2 2
MIRT658095 FOXO1 forkhead box O1 2 2
MIRT658860 DTX3L deltex E3 ubiquitin ligase 3L 2 2
MIRT658988 DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 2 2
MIRT660767 ALDH6A1 aldehyde dehydrogenase 6 family member A1 2 2
MIRT661622 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT661694 TFDP2 transcription factor Dp-2 2 2
MIRT662208 PLA2G4E phospholipase A2 group IVE 2 2
MIRT662443 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT664422 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT687505 NECAB1 N-terminal EF-hand calcium binding protein 1 2 2
MIRT689910 SOD2 superoxide dismutase 2 2 2
MIRT690781 PLA2G2C phospholipase A2 group IIC 2 2
MIRT698488 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT699685 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT700926 PDS5A PDS5 cohesin associated factor A 2 2
MIRT702258 LMNB1 lamin B1 2 2
MIRT703166 GPR137C G protein-coupled receptor 137C 2 2
MIRT703242 GNS glucosamine (N-acetyl)-6-sulfatase 2 2
MIRT704737 CENPQ centromere protein Q 2 2
MIRT707310 GLRX2 glutaredoxin 2 2 2
MIRT710021 KCNQ5 potassium voltage-gated channel subfamily Q member 5 2 2
MIRT712212 SCOC short coiled-coil protein 2 2
MIRT714742 SETBP1 SET binding protein 1 2 2
MIRT718268 ZNF749 zinc finger protein 749 2 2
MIRT720553 DYRK4 dual specificity tyrosine phosphorylation regulated kinase 4 2 2
MIRT722248 RBM41 RNA binding motif protein 41 2 2
MIRT723767 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT723977 KIAA0146 scaffolding protein involved in DNA repair 1 1
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4282 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4282 Neoadjuvant chemotherapy sensitive tissue (breast cancer)

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