miRTarBase - #MIRT512413


—
pre-miRNA Information
pre-miRNA hsa-mir-2117   
Genomic Coordinates chr17: 43444806 - 43444885
Description Homo sapiens miR-2117 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2117
Sequence 51| UGUUCUCUUUGCCAAGGACAG |71
Evidence Experimental
Experiments 454
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1255384593 12 dbSNP
rs1227862494 14 dbSNP
rs1458444919 16 dbSNP
rs1309101018 17 dbSNP
rs1159219853 18 dbSNP
rs1344029538 19 dbSNP
rs747666550 20 dbSNP
rs770495894 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KIAA0391   
Synonyms MRPP3, PRORP
Description KIAA0391
Transcript NM_014672   
Expression
Putative miRNA Targets on KIAA0391
3'UTR of KIAA0391
(miRNA target sites are highlighted)		 
>KIAA0391|NM_014672|3'UTR
   1 AGATTCTTACCTCTATGCTAAGTTTGTGTTTGGGTACCCTCTAGGTTGGCATCAGAGGCTCTTGAGCTGGTGTTTGTTTA
  81 GGGCATTGCCTCTGTCCTGAAGATAAAAGGATTCTATTAACAGCATTGACATTGATTTTTTAATGAAATGAGATATATCT
 161 TTTCATAACCAGCTGCGTTTTTTTCCCCTAACATTTGTTTTTGGAGGCTTATCAAGAGTTGGAGAACTTAGTGTAGAGCA
 241 AAACCTGCATTTCTCCTACTGGGCCAGCTATTCCACTTAGCTTGGGTGACTAATAGTGCTTTTGGTATCCATTTTTTGCT
 321 ACTTCTGACCTTGCCTTCCAGGCCTACCAATAGCAGAATCAATCCATCTGTCCCTGAGATACTCATGTTGTTTCAAATGC
 401 CTCCTCCCATTTCTGGCATAGTCTCATTCTCTGTATGTTATGCCCTATCCACATGGAATCATTTATCGTCCTCTGTAATA
 481 AACTGGCCAAGATACTAAAGGCTTACTATTCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaCAGGAACC--------GUU-----UCUCUUGu 5'
            ||::||||        |||     :|||||| 
Target 5' ttGTTTTTGGAGGCTTATCAAGAGTTGGAGAACt 3'
 195 - 228 133.00 -16.70
2 
miRNA  3' gaCAGGAACCGUUUCUCUUgu 5'
            |||||    :|||| ||  
Target 5' ctGTCCT----GAAGATAAaa 3'
 92 - 108 105.00 -9.90
3 
miRNA  3' gacaggAACCGU-UUCUCUugu 5'
                ||||||  ||||:   
Target 5' tctaggTTGGCATCAGAGGctc 3'
 40 - 61 103.00 -11.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30543487 2 COSMIC
COSN31586758 27 COSMIC
COSN508872 39 COSMIC
COSN30447367 40 COSMIC
COSN30160110 56 COSMIC
COSN30526963 65 COSMIC
COSN30164759 74 COSMIC
COSN31520279 79 COSMIC
COSN30153655 93 COSMIC
COSN31481332 95 COSMIC
COSN30160739 100 COSMIC
COSN31544791 115 COSMIC
COSN31530208 160 COSMIC
COSN30485973 165 COSMIC
COSN28879572 185 COSMIC
COSN8152129 394 COSMIC
COSN6247422 513 COSMIC
COSN14563025 736 COSMIC
COSN18756399 767 COSMIC
COSN8828738 1076 COSMIC
COSN25430652 1799 COSMIC
COSN16978389 2032 COSMIC
COSN21864315 2169 COSMIC
COSN26082492 2260 COSMIC
COSN15411141 2580 COSMIC
COSN29361324 3829 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs150939416 2 dbSNP
rs1396623865 3 dbSNP
rs528870370 5 dbSNP
rs577331219 6 dbSNP
rs1233759438 11 dbSNP
rs546361020 16 dbSNP
rs1351053719 17 dbSNP
rs1026748118 25 dbSNP
rs1169870821 35 dbSNP
rs1433942826 39 dbSNP
rs769360479 42 dbSNP
rs772931336 51 dbSNP
rs1389879941 61 dbSNP
rs755320612 62 dbSNP
rs1470190979 64 dbSNP
rs760647876 70 dbSNP
rs1333771608 71 dbSNP
rs12640 77 dbSNP
rs1004073837 78 dbSNP
rs768522762 84 dbSNP
rs1450526371 95 dbSNP
rs1273175923 109 dbSNP
rs1197113482 115 dbSNP
rs1339648987 117 dbSNP
rs554893171 123 dbSNP
rs959981881 126 dbSNP
rs1234787350 131 dbSNP
rs1372960802 133 dbSNP
rs1301126578 135 dbSNP
rs10715 136 dbSNP
rs1435740277 136 dbSNP
rs1023266679 138 dbSNP
rs1408381039 143 dbSNP
rs1370224175 146 dbSNP
rs969425127 150 dbSNP
rs150139006 153 dbSNP
rs1393721026 157 dbSNP
rs1191119610 163 dbSNP
rs887306223 174 dbSNP
rs940252664 177 dbSNP
rs1041293283 178 dbSNP
rs1481845438 178 dbSNP
rs956768283 178 dbSNP
rs1273422318 185 dbSNP
rs988296342 186 dbSNP
rs1230962030 196 dbSNP
rs540668360 197 dbSNP
rs1335018518 198 dbSNP
rs145578423 202 dbSNP
rs1248793453 216 dbSNP
rs1218521133 222 dbSNP
rs1028328192 234 dbSNP
rs912721489 240 dbSNP
rs530005201 241 dbSNP
rs1281316509 254 dbSNP
rs549778949 258 dbSNP
rs1183163460 261 dbSNP
rs1350006454 262 dbSNP
rs1235142053 264 dbSNP
rs569849370 270 dbSNP
rs1436890231 271 dbSNP
rs761557278 274 dbSNP
rs1164242552 275 dbSNP
rs753296298 280 dbSNP
rs7218 292 dbSNP
rs1410839283 308 dbSNP
rs1157378306 311 dbSNP
rs921486990 312 dbSNP
rs1250499719 318 dbSNP
rs1188211105 321 dbSNP
rs772794855 322 dbSNP
rs1486458275 323 dbSNP
rs1235477657 325 dbSNP
rs993132064 326 dbSNP
rs1024232099 329 dbSNP
rs931013179 337 dbSNP
rs1463147982 340 dbSNP
rs1226563856 350 dbSNP
rs1166382116 353 dbSNP
rs762521129 356 dbSNP
rs1416791111 361 dbSNP
rs1377274949 365 dbSNP
rs552344465 375 dbSNP
rs1048518437 377 dbSNP
rs1431891566 381 dbSNP
rs1347363288 382 dbSNP
rs969678918 383 dbSNP
rs765912617 386 dbSNP
rs1457236368 389 dbSNP
rs920298125 398 dbSNP
rs930370252 401 dbSNP
rs1165045350 403 dbSNP
rs983248805 407 dbSNP
rs1411145512 408 dbSNP
rs566218203 410 dbSNP
rs1352309531 419 dbSNP
rs1412878184 427 dbSNP
rs1243702885 432 dbSNP
rs1292088079 442 dbSNP
rs1464395513 459 dbSNP
rs1273835567 462 dbSNP
rs1355558171 467 dbSNP
rs1057029206 468 dbSNP
rs940219619 469 dbSNP
rs1012723344 470 dbSNP
rs1364516235 472 dbSNP
rs1041239558 487 dbSNP
rs751092213 491 dbSNP
rs901439242 498 dbSNP
rs1318962306 507 dbSNP
rs1246521399 512 dbSNP
rs1395897505 516 dbSNP
rs148950551 530 dbSNP
rs1249331235 534 dbSNP
rs192001234 541 dbSNP
rs764465843 548 dbSNP
rs1163630560 560 dbSNP
rs1049701423 561 dbSNP
rs904553591 565 dbSNP
rs1186467686 568 dbSNP
rs1000896086 586 dbSNP
rs969014008 586 dbSNP
rs1000662160 610 dbSNP
rs1032742949 612 dbSNP
rs11849346 614 dbSNP
rs988181605 615 dbSNP
rs1309511901 616 dbSNP
rs537762235 617 dbSNP
rs1484954922 619 dbSNP
rs1187873252 621 dbSNP
rs183880660 622 dbSNP
rs1014105312 623 dbSNP
rs1385659005 625 dbSNP
rs1387870658 626 dbSNP
rs1292448938 635 dbSNP
rs1024179771 638 dbSNP
rs1462134494 642 dbSNP
rs61988270 643 dbSNP
rs187538214 644 dbSNP
rs1027720161 645 dbSNP
rs1428842837 647 dbSNP
rs921553282 649 dbSNP
rs931546443 652 dbSNP
rs1048094163 655 dbSNP
rs779419879 665 dbSNP
rs746083640 670 dbSNP
rs983582355 673 dbSNP
rs907618786 675 dbSNP
rs939629418 684 dbSNP
rs961807492 699 dbSNP
rs746513060 703 dbSNP
rs1056912783 704 dbSNP
rs1349045211 705 dbSNP
rs895541217 708 dbSNP
rs1012772151 729 dbSNP
rs1168230518 733 dbSNP
rs976879239 735 dbSNP
rs1015990464 736 dbSNP
rs1372209684 741 dbSNP
rs1044602520 742 dbSNP
rs1174116775 750 dbSNP
rs1299940296 750 dbSNP
rs1375760421 750 dbSNP
rs3058468 750 dbSNP
rs546643828 750 dbSNP
rs568487122 750 dbSNP
rs1464436891 757 dbSNP
rs904466653 761 dbSNP
rs79820664 767 dbSNP
rs879698780 768 dbSNP
rs1159810585 769 dbSNP
rs1312263488 770 dbSNP
rs1375520867 771 dbSNP
rs1473608260 775 dbSNP
rs922799698 778 dbSNP
rs1181647442 791 dbSNP
rs1486130570 793 dbSNP
rs1884715 802 dbSNP
rs1292970734 804 dbSNP
rs1032382565 809 dbSNP
rs190463395 811 dbSNP
rs892469096 817 dbSNP
rs1049981616 819 dbSNP
rs8009666 825 dbSNP
rs936020191 839 dbSNP
rs1355718708 847 dbSNP
rs1335828642 852 dbSNP
rs965415297 853 dbSNP
rs975636922 854 dbSNP
rs1028903696 860 dbSNP
rs747097690 864 dbSNP
rs34217104 871 dbSNP
rs1210780881 872 dbSNP
rs540678556 882 dbSNP
rs1158552433 886 dbSNP
rs1475636270 887 dbSNP
rs984783484 889 dbSNP
rs1484259303 896 dbSNP
rs908762772 900 dbSNP
rs1014386896 901 dbSNP
rs776504682 910 dbSNP
rs1185746941 916 dbSNP
rs1261150977 918 dbSNP
rs1429295133 921 dbSNP
rs1190758259 924 dbSNP
rs1207336986 925 dbSNP
rs939683651 925 dbSNP
rs1045571781 937 dbSNP
rs1227275974 939 dbSNP
rs748092568 942 dbSNP
rs138341483 952 dbSNP
rs549031604 961 dbSNP
rs951761677 967 dbSNP
rs1437131417 971 dbSNP
rs1044269715 972 dbSNP
rs1004558750 977 dbSNP
rs904350956 980 dbSNP
rs935809182 981 dbSNP
rs1378185271 986 dbSNP
rs1015036166 988 dbSNP
rs1052973491 998 dbSNP
rs1161675067 1002 dbSNP
rs1373935006 1007 dbSNP
rs1472592576 1007 dbSNP
rs1190931681 1012 dbSNP
rs965762118 1019 dbSNP
rs182653735 1025 dbSNP
rs1019560607 1026 dbSNP
rs922747332 1033 dbSNP
rs1291414140 1034 dbSNP
rs529954285 1035 dbSNP
rs1207640668 1038 dbSNP
rs953838638 1044 dbSNP
rs559157686 1047 dbSNP
rs563480721 1051 dbSNP
rs769512661 1069 dbSNP
rs1362824374 1070 dbSNP
rs1322200377 1082 dbSNP
rs953002677 1082 dbSNP
rs1369232007 1088 dbSNP
rs926234249 1099 dbSNP
rs1234070588 1105 dbSNP
rs749285274 1107 dbSNP
rs1332838793 1111 dbSNP
rs984279331 1120 dbSNP
rs1015874383 1121 dbSNP
rs961600362 1122 dbSNP
rs992520085 1128 dbSNP
rs1237560665 1134 dbSNP
rs532425860 1140 dbSNP
rs936285829 1141 dbSNP
rs552409501 1146 dbSNP
rs186928548 1147 dbSNP
rs528615370 1153 dbSNP
rs1479298095 1155 dbSNP
rs1247898152 1156 dbSNP
rs1196171632 1171 dbSNP
rs1478142804 1177 dbSNP
rs548664839 1180 dbSNP
rs1210819512 1183 dbSNP
rs552681095 1190 dbSNP
rs980260709 1201 dbSNP
rs1219673038 1202 dbSNP
rs925692002 1206 dbSNP
rs935846326 1213 dbSNP
rs1192728772 1226 dbSNP
rs1336493575 1238 dbSNP
rs950099043 1247 dbSNP
rs1408241995 1248 dbSNP
rs1370280453 1250 dbSNP
rs1052866518 1251 dbSNP
rs1045862958 1255 dbSNP
rs1267836633 1256 dbSNP
rs537076748 1263 dbSNP
rs192859893 1266 dbSNP
rs1001370724 1269 dbSNP
rs570550398 1269 dbSNP
rs1250732779 1273 dbSNP
rs571100509 1279 dbSNP
rs116210187 1286 dbSNP
rs1443965001 1291 dbSNP
rs1457370716 1312 dbSNP
rs887691613 1318 dbSNP
rs762656947 1324 dbSNP
rs553156151 1330 dbSNP
rs1290311132 1332 dbSNP
rs1226747249 1339 dbSNP
rs114748917 1343 dbSNP
rs1313761484 1355 dbSNP
rs997200382 1356 dbSNP
rs1326948806 1365 dbSNP
rs376546290 1379 dbSNP
rs954178583 1382 dbSNP
rs985639477 1383 dbSNP
rs1033635150 1386 dbSNP
rs1390108391 1389 dbSNP
rs1334077975 1399 dbSNP
rs1306998453 1408 dbSNP
rs888518651 1410 dbSNP
rs1317562041 1416 dbSNP
rs1005744934 1420 dbSNP
rs75053077 1421 dbSNP
rs1471380597 1424 dbSNP
rs1410724914 1426 dbSNP
rs554280157 1427 dbSNP
rs961655776 1428 dbSNP
rs184405522 1436 dbSNP
rs1014510919 1443 dbSNP
rs35225046 1459 dbSNP
rs377321112 1459 dbSNP
rs779290589 1459 dbSNP
rs970136076 1460 dbSNP
rs865813093 1463 dbSNP
rs1214564488 1470 dbSNP
rs1328642488 1472 dbSNP
rs1247012423 1483 dbSNP
rs913207768 1486 dbSNP
rs1230310024 1502 dbSNP
rs1377341495 1508 dbSNP
rs1164074599 1511 dbSNP
rs7493705 1517 dbSNP
rs1436398511 1521 dbSNP
rs981484429 1522 dbSNP
rs767145601 1535 dbSNP
rs187710339 1536 dbSNP
rs1048882055 1539 dbSNP
rs1164958574 1540 dbSNP
rs114050624 1545 dbSNP
rs1411298553 1549 dbSNP
rs1181099521 1554 dbSNP
rs1449895553 1570 dbSNP
rs1472618725 1572 dbSNP
rs944505267 1574 dbSNP
rs1464494774 1585 dbSNP
rs1183645923 1591 dbSNP
rs142715268 1609 dbSNP
rs1403967033 1614 dbSNP
rs1036709160 1617 dbSNP
rs535767783 1626 dbSNP
rs1320162000 1631 dbSNP
rs997148218 1634 dbSNP
rs577065947 1635 dbSNP
rs921844508 1639 dbSNP
rs1351969462 1641 dbSNP
rs1296027973 1643 dbSNP
rs1028650624 1650 dbSNP
rs888863125 1652 dbSNP
rs144997714 1654 dbSNP
rs1459086129 1660 dbSNP
rs1347728683 1661 dbSNP
rs1049734991 1664 dbSNP
rs1430154378 1669 dbSNP
rs1391859286 1673 dbSNP
rs759914067 1692 dbSNP
rs1186520204 1693 dbSNP
rs888554862 1700 dbSNP
rs1005628964 1704 dbSNP
rs1354921097 1711 dbSNP
rs1033169096 1715 dbSNP
rs1037240110 1716 dbSNP
rs897329690 1718 dbSNP
rs957785057 1725 dbSNP
rs374497978 1730 dbSNP
rs1206207900 1747 dbSNP
rs1234118877 1750 dbSNP
rs1292371394 1751 dbSNP
rs1228250318 1754 dbSNP
rs1313330415 1765 dbSNP
rs1304103153 1785 dbSNP
rs1323251936 1795 dbSNP
rs2415284 1797 dbSNP
rs971353598 1799 dbSNP
rs1410057667 1800 dbSNP
rs1372111827 1807 dbSNP
rs1250567368 1817 dbSNP
rs1166503602 1823 dbSNP
rs1483318878 1826 dbSNP
rs981431753 1831 dbSNP
rs1001637980 1833 dbSNP
rs548381076 1843 dbSNP
rs937421103 1851 dbSNP
rs985307704 1866 dbSNP
rs1183097371 1867 dbSNP
rs1415575318 1873 dbSNP
rs957389220 1881 dbSNP
rs1204848788 1888 dbSNP
rs1483813748 1906 dbSNP
rs1238331665 1907 dbSNP
rs988524351 1911 dbSNP
rs1426393729 1914 dbSNP
rs912950775 1928 dbSNP
rs1282103161 1940 dbSNP
rs965865417 1947 dbSNP
rs1371568182 1950 dbSNP
rs909024403 1952 dbSNP
rs867743309 1953 dbSNP
rs750865611 1954 dbSNP
rs975866058 1955 dbSNP
rs562089921 1957 dbSNP
rs1390581658 1967 dbSNP
rs1311658049 1983 dbSNP
rs1374923585 1985 dbSNP
rs1304507850 1987 dbSNP
rs1428626992 1991 dbSNP
rs531027480 1991 dbSNP
rs758614630 1993 dbSNP
rs1160042232 1999 dbSNP
rs1286150869 2007 dbSNP
rs1473637577 2008 dbSNP
rs796550927 2019 dbSNP
rs901761510 2021 dbSNP
rs1424758960 2040 dbSNP
rs933279949 2041 dbSNP
rs1214233472 2045 dbSNP
rs1064248 2068 dbSNP
rs1050221329 2075 dbSNP
rs1208771516 2076 dbSNP
rs1330665269 2081 dbSNP
rs1399973200 2084 dbSNP
rs1286055381 2101 dbSNP
rs909879781 2103 dbSNP
rs193099903 2105 dbSNP
rs1207194835 2106 dbSNP
rs1340775979 2107 dbSNP
rs1314641142 2115 dbSNP
rs1394177560 2116 dbSNP
rs1000590923 2118 dbSNP
rs1032524408 2119 dbSNP
rs1386637053 2125 dbSNP
rs539767052 2131 dbSNP
rs893263905 2132 dbSNP
rs1158147377 2143 dbSNP
rs1458618871 2145 dbSNP
rs1370511668 2151 dbSNP
rs1185902349 2157 dbSNP
rs1444442886 2160 dbSNP
rs1249161604 2162 dbSNP
rs1191116009 2164 dbSNP
rs546855859 2165 dbSNP
rs1265700275 2166 dbSNP
rs1204124870 2170 dbSNP
rs1356653550 2171 dbSNP
rs747279354 2174 dbSNP
rs1037124451 2194 dbSNP
rs1242310589 2199 dbSNP
rs1484653215 2203 dbSNP
rs1437200249 2211 dbSNP
rs1185590361 2214 dbSNP
rs1391158750 2226 dbSNP
rs897215010 2228 dbSNP
rs1406127825 2229 dbSNP
rs1393102338 2230 dbSNP
rs11294873 2232 dbSNP
rs1161725749 2232 dbSNP
rs1170956641 2232 dbSNP
rs1448216877 2232 dbSNP
rs398024775 2232 dbSNP
rs950215715 2244 dbSNP
rs76367401 2247 dbSNP
rs1324192413 2248 dbSNP
rs7158151 2251 dbSNP
rs1003147471 2252 dbSNP
rs1415565311 2255 dbSNP
rs1275109769 2259 dbSNP
rs1336199657 2262 dbSNP
rs1034336322 2283 dbSNP
rs958978411 2287 dbSNP
rs1269561416 2291 dbSNP
rs1437249904 2293 dbSNP
rs560247918 2293 dbSNP
rs11392565 2294 dbSNP
rs397711908 2294 dbSNP
rs397948651 2294 dbSNP
rs535682625 2294 dbSNP
rs113220132 2297 dbSNP
rs1371494346 2309 dbSNP
rs112733905 2310 dbSNP
rs1428267512 2314 dbSNP
rs1419401497 2317 dbSNP
rs909298149 2318 dbSNP
rs1478067848 2337 dbSNP
rs1378869798 2338 dbSNP
rs892813141 2339 dbSNP
rs79228904 2351 dbSNP
rs1020012134 2359 dbSNP
rs1206990575 2368 dbSNP
rs751036851 2371 dbSNP
rs537102760 2372 dbSNP
rs184901899 2381 dbSNP
rs923133036 2388 dbSNP
rs1347132247 2394 dbSNP
rs1273165640 2399 dbSNP
rs1223080772 2408 dbSNP
rs1344168170 2413 dbSNP
rs576735870 2420 dbSNP
rs1310144064 2422 dbSNP
rs562445551 2428 dbSNP
rs1280062088 2432 dbSNP
rs1335368152 2437 dbSNP
rs953456742 2439 dbSNP
rs113032047 2452 dbSNP
rs1403661648 2453 dbSNP
rs933226030 2454 dbSNP
rs1050318825 2456 dbSNP
rs201666268 2457 dbSNP
rs559710779 2459 dbSNP
rs910195253 2460 dbSNP
rs984724991 2463 dbSNP
rs909090779 2466 dbSNP
rs941355742 2469 dbSNP
rs1210658921 2476 dbSNP
rs936336567 2482 dbSNP
rs1053505902 2486 dbSNP
rs972705935 2487 dbSNP
rs1214630933 2488 dbSNP
rs918698475 2492 dbSNP
rs892202292 2500 dbSNP
rs1290439834 2502 dbSNP
rs1222287684 2518 dbSNP
rs1248305058 2525 dbSNP
rs573169429 2530 dbSNP
rs1009356376 2538 dbSNP
rs1450769788 2539 dbSNP
rs1192086157 2540 dbSNP
rs777525259 2545 dbSNP
rs906032999 2552 dbSNP
rs1252792612 2553 dbSNP
rs1468817181 2566 dbSNP
rs907397050 2570 dbSNP
rs1478602249 2571 dbSNP
rs1003096528 2576 dbSNP
rs542087310 2581 dbSNP
rs1405867888 2597 dbSNP
rs1398608338 2626 dbSNP
rs1034606026 2632 dbSNP
rs559545441 2646 dbSNP
rs1182264285 2650 dbSNP
rs1006628818 2678 dbSNP
rs530283774 2682 dbSNP
rs1473684579 2685 dbSNP
rs962420501 2687 dbSNP
rs561882831 2691 dbSNP
rs1182982274 2693 dbSNP
rs923079242 2701 dbSNP
rs1270112380 2702 dbSNP
rs1213852953 2706 dbSNP
rs1316589278 2718 dbSNP
rs954563307 2733 dbSNP
rs1160138436 2738 dbSNP
rs1290913557 2751 dbSNP
rs1230362102 2752 dbSNP
rs749079445 2764 dbSNP
rs1314954264 2765 dbSNP
rs910467083 2773 dbSNP
rs1290136966 2774 dbSNP
rs893364098 2774 dbSNP
rs770779643 2776 dbSNP
rs1439025449 2779 dbSNP
rs1323570737 2781 dbSNP
rs1053859106 2799 dbSNP
rs1437098215 2806 dbSNP
rs1165115645 2809 dbSNP
rs45511993 2811 dbSNP
rs1383162933 2832 dbSNP
rs759227881 2848 dbSNP
rs1450031322 2862 dbSNP
rs77903663 2870 dbSNP
rs3742370 2871 dbSNP
rs1330717286 2872 dbSNP
rs1247492377 2875 dbSNP
rs1357653321 2881 dbSNP
rs141601344 2881 dbSNP
rs745577786 2887 dbSNP
rs1029122512 2888 dbSNP
rs1344976881 2899 dbSNP
rs894719025 2906 dbSNP
rs1212283981 2926 dbSNP
rs1006497542 2932 dbSNP
rs1293688020 2933 dbSNP
rs1406409585 2934 dbSNP
rs1363434434 2939 dbSNP
rs1231712286 2953 dbSNP
rs564339159 2958 dbSNP
rs1016208456 2965 dbSNP
rs1430217934 2972 dbSNP
rs1391928689 2975 dbSNP
rs1016665624 2976 dbSNP
rs897839862 2978 dbSNP
rs993519704 2981 dbSNP
rs150872139 2982 dbSNP
rs528194651 2991 dbSNP
rs546568243 2994 dbSNP
rs918588636 2996 dbSNP
rs1193073769 2997 dbSNP
rs566871550 3002 dbSNP
rs1460020808 3009 dbSNP
rs1164558689 3010 dbSNP
rs189219721 3015 dbSNP
rs1204446685 3017 dbSNP
rs981556607 3035 dbSNP
rs549314604 3037 dbSNP
rs569406001 3042 dbSNP
rs536760329 3045 dbSNP
rs927339381 3049 dbSNP
rs958174796 3051 dbSNP
rs1398445129 3052 dbSNP
rs557051349 3056 dbSNP
rs913528776 3058 dbSNP
rs1359762809 3061 dbSNP
rs914852518 3062 dbSNP
rs1479520639 3064 dbSNP
rs76317015 3068 dbSNP
rs981824781 3069 dbSNP
rs1409164587 3070 dbSNP
rs867752053 3074 dbSNP
rs1183250006 3077 dbSNP
rs779769292 3079 dbSNP
rs1473738961 3100 dbSNP
rs552367580 3101 dbSNP
rs1288350551 3107 dbSNP
rs770775980 3108 dbSNP
rs1258332910 3130 dbSNP
rs1204996755 3131 dbSNP
rs1231060105 3132 dbSNP
rs901521307 3133 dbSNP
rs1337246686 3135 dbSNP
rs997559136 3140 dbSNP
rs1390708949 3144 dbSNP
rs762386519 3156 dbSNP
rs888840835 3170 dbSNP
rs1056350466 3171 dbSNP
rs894672353 3175 dbSNP
rs961994979 3177 dbSNP
rs570958682 3189 dbSNP
rs993416159 3193 dbSNP
rs1181502112 3209 dbSNP
rs539485470 3212 dbSNP
rs1206519145 3213 dbSNP
rs566261336 3215 dbSNP
rs942249185 3222 dbSNP
rs1182363855 3224 dbSNP
rs765884143 3235 dbSNP
rs1187458630 3239 dbSNP
rs1208908369 3241 dbSNP
rs1369323915 3242 dbSNP
rs1352433463 3243 dbSNP
rs1473908876 3246 dbSNP
rs981823932 3273 dbSNP
rs897789958 3277 dbSNP
rs1394070181 3286 dbSNP
rs959027663 3289 dbSNP
rs1308619492 3290 dbSNP
rs993466984 3292 dbSNP
rs1030322727 3294 dbSNP
rs552997325 3305 dbSNP
rs890537750 3313 dbSNP
rs1450375036 3320 dbSNP
rs1382066195 3323 dbSNP
rs376239945 3326 dbSNP
rs1321335932 3333 dbSNP
rs1384037884 3340 dbSNP
rs1383046196 3343 dbSNP
rs990309722 3348 dbSNP
rs139377239 3350 dbSNP
rs1311540671 3351 dbSNP
rs181540151 3352 dbSNP
rs1241940354 3353 dbSNP
rs1246541923 3354 dbSNP
rs763179756 3363 dbSNP
rs868304345 3370 dbSNP
rs766781894 3373 dbSNP
rs957908737 3378 dbSNP
rs1488652067 3379 dbSNP
rs933020937 3400 dbSNP
rs1341970633 3403 dbSNP
rs1358608651 3408 dbSNP
rs1298303844 3416 dbSNP
rs1229689588 3417 dbSNP
rs1324833771 3421 dbSNP
rs1229787151 3431 dbSNP
rs751667189 3434 dbSNP
rs7143017 3438 dbSNP
rs1367788799 3461 dbSNP
rs1484720890 3463 dbSNP
rs188756081 3464 dbSNP
rs527569588 3464 dbSNP
rs888900927 3464 dbSNP
rs1199897212 3465 dbSNP
rs181130905 3468 dbSNP
rs1037415596 3478 dbSNP
rs1480578394 3479 dbSNP
rs897669289 3484 dbSNP
rs981773736 3485 dbSNP
rs927640270 3488 dbSNP
rs937731433 3491 dbSNP
rs1024915004 3497 dbSNP
rs1197494637 3500 dbSNP
rs564633863 3502 dbSNP
rs1234182351 3503 dbSNP
rs990598041 3505 dbSNP
rs768542098 3513 dbSNP
rs916042469 3515 dbSNP
rs942215111 3516 dbSNP
rs971031752 3517 dbSNP
rs1038323999 3519 dbSNP
rs1191316617 3528 dbSNP
rs755260583 3532 dbSNP
rs28665705 3541 dbSNP
rs1051697547 3545 dbSNP
rs1408736343 3556 dbSNP
rs890483768 3570 dbSNP
rs1008025266 3571 dbSNP
rs568263466 3575 dbSNP
rs1039136061 3578 dbSNP
rs1448713614 3582 dbSNP
rs1480507626 3585 dbSNP
rs540240837 3586 dbSNP
rs1392000553 3593 dbSNP
rs1010733942 3603 dbSNP
rs1233260535 3605 dbSNP
rs752827637 3607 dbSNP
rs1436036947 3609 dbSNP
rs560068558 3610 dbSNP
rs914626772 3615 dbSNP
rs756017091 3617 dbSNP
rs1419575423 3618 dbSNP
rs1351433727 3624 dbSNP
rs1397405165 3628 dbSNP
rs1440517487 3637 dbSNP
rs977537426 3642 dbSNP
rs1335519158 3644 dbSNP
rs1364887055 3647 dbSNP
rs147371718 3648 dbSNP
rs1300296373 3649 dbSNP
rs1346289306 3650 dbSNP
rs1233162979 3652 dbSNP
rs959046902 3660 dbSNP
rs1408387655 3661 dbSNP
rs923572400 3666 dbSNP
rs1256599512 3670 dbSNP
rs990937421 3671 dbSNP
rs777650180 3675 dbSNP
rs1462656028 3680 dbSNP
rs1241372896 3689 dbSNP
rs962810468 3695 dbSNP
rs1203226063 3700 dbSNP
rs1247685810 3718 dbSNP
rs1464254531 3720 dbSNP
rs749259829 3724 dbSNP
rs1188909837 3727 dbSNP
rs549617859 3729 dbSNP
rs919448592 3736 dbSNP
rs1350497366 3739 dbSNP
rs374581649 3740 dbSNP
rs1455070562 3746 dbSNP
rs1051977852 3749 dbSNP
rs1377693856 3752 dbSNP
rs531958159 3753 dbSNP
rs1345391431 3758 dbSNP
rs745489889 3761 dbSNP
rs551676763 3767 dbSNP
rs1398732551 3769 dbSNP
rs185976627 3776 dbSNP
rs1039481214 3778 dbSNP
rs1164067640 3778 dbSNP
rs1387397616 3786 dbSNP
rs1383351325 3794 dbSNP
rs547637625 3798 dbSNP
rs553009794 3799 dbSNP
rs1244056874 3801 dbSNP
rs191027346 3809 dbSNP
rs139563561 3814 dbSNP
rs1446729850 3817 dbSNP
rs897553169 3831 dbSNP
rs1248749454 3841 dbSNP
rs144988683 3846 dbSNP
rs535705765 3850 dbSNP
rs1003438868 3854 dbSNP
rs1362129350 3857 dbSNP
rs1290198760 3867 dbSNP
rs1302663921 3871 dbSNP
rs995343735 3875 dbSNP
rs1303500190 3880 dbSNP
rs80263156 3886 dbSNP
rs557330731 3890 dbSNP
rs1162924965 3895 dbSNP
rs1267610987 3896 dbSNP
rs1429125156 3899 dbSNP
rs894476656 3905 dbSNP
rs1011505043 3906 dbSNP
rs1021684456 3908 dbSNP
rs967418092 3910 dbSNP
rs1225160692 3917 dbSNP
rs1489979497 3922 dbSNP
rs1291689220 3927 dbSNP
rs1330040161 3932 dbSNP
rs1307508779 3933 dbSNP
rs533324710 3937 dbSNP
rs1269771117 3943 dbSNP
rs75790833 3944 dbSNP
rs1339419309 3949 dbSNP
rs959265339 3953 dbSNP
rs1030909111 3961 dbSNP
rs1190521725 3964 dbSNP
rs1268034343 3965 dbSNP
rs955023941 3967 dbSNP
rs1292810161 3969 dbSNP
rs1200441269 3973 dbSNP
rs1462449973 3977 dbSNP
rs61988271 3979 dbSNP
rs1017049364 3980 dbSNP
rs182313756 3988 dbSNP
rs373896218 3990 dbSNP
rs1430232101 3991 dbSNP
rs962473845 3992 dbSNP
rs919036522 3993 dbSNP
rs929030792 3997 dbSNP
rs1410585536 3999 dbSNP
rs1178233155 4003 dbSNP
rs1481925097 4008 dbSNP
rs75549332 4009 dbSNP
rs919395960 4011 dbSNP
rs1316831883 4017 dbSNP
rs1263302112 4019 dbSNP
rs1224978459 4022 dbSNP
rs950901959 4030 dbSNP
rs1300364167 4031 dbSNP
rs1457753483 4032 dbSNP
rs987642553 4035 dbSNP
rs912151988 4046 dbSNP
rs1296444025 4051 dbSNP
rs1446128985 4053 dbSNP
rs1406932798 4055 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 9692.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gacaggaaccguUUCUCUUGu 5'
                      :||||||| 
Target 5' -----------uGAGAGAACu 3'
 		1 - 10
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000534898.4 | 3UTR | UGAGAGAACUUGAGAGAA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
50 hsa-miR-2117 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080059 TGIF1 TGFB induced factor homeobox 1 2 2
MIRT253245 ZNF264 zinc finger protein 264 2 4
MIRT279706 EIF2S1 eukaryotic translation initiation factor 2 subunit alpha 2 4
MIRT359344 TMEM167A transmembrane protein 167A 2 2
MIRT465598 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT479860 CCDC6 coiled-coil domain containing 6 2 2
MIRT512413 KIAA0391 KIAA0391 2 2
MIRT525342 TUBGCP4 tubulin gamma complex associated protein 4 2 2
MIRT528092 UCHL3 ubiquitin C-terminal hydrolase L3 2 2
MIRT529254 TRIM4 tripartite motif containing 4 2 4
MIRT550782 VAV3 vav guanine nucleotide exchange factor 3 2 2
MIRT554467 SAMD12 sterile alpha motif domain containing 12 2 2
MIRT560164 ZNF286A zinc finger protein 286A 2 2
MIRT562613 BTF3L4 basic transcription factor 3 like 4 2 2
MIRT568507 ARF1 ADP ribosylation factor 1 2 2
MIRT571536 ZNF286B zinc finger protein 286B 2 2
MIRT609660 ITIH5 inter-alpha-trypsin inhibitor heavy chain family member 5 2 2
MIRT612022 PAK6 p21 (RAC1) activated kinase 6 2 8
MIRT615677 NAV2 neuron navigator 2 2 2
MIRT616035 SCO1 SCO1, cytochrome c oxidase assembly protein 2 2
MIRT617771 C17orf105 chromosome 17 open reading frame 105 2 2
MIRT628757 MX2 MX dynamin like GTPase 2 2 4
MIRT635089 AKIRIN1 akirin 1 2 2
MIRT638261 SIX1 SIX homeobox 1 2 2
MIRT638492 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT639400 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT641791 USP32 ubiquitin specific peptidase 32 2 2
MIRT642309 FPR1 formyl peptide receptor 1 2 2
MIRT645902 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT649701 ZNF175 zinc finger protein 175 2 2
MIRT656848 KLF13 Kruppel like factor 13 2 2
MIRT659911 CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 2 2
MIRT667275 NAV1 neuron navigator 1 2 2
MIRT674145 ZNF793 zinc finger protein 793 2 2
MIRT692839 C1orf50 chromosome 1 open reading frame 50 2 2
MIRT698520 TFRC transferrin receptor 2 2
MIRT698731 STX6 syntaxin 6 2 4
MIRT700931 PDPK1 3-phosphoinositide dependent protein kinase 1 2 2
MIRT706080 HNRNPU heterogeneous nuclear ribonucleoprotein U 2 2
MIRT710008 SH3GLB1 SH3 domain containing GRB2 like, endophilin B1 2 2
MIRT711059 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT711285 PSME3 proteasome activator subunit 3 2 2
MIRT716172 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT716761 TRABD2A TraB domain containing 2A 2 2
MIRT718683 FZD2 frizzled class receptor 2 2 2
MIRT719675 SPDYE1 speedy/RINGO cell cycle regulator family member E1 2 2
MIRT721610 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT722188 DNAJC9 DnaJ heat shock protein family (Hsp40) member C9 2 2
MIRT725156 SEC62 SEC62 homolog, preprotein translocation factor 2 2
MIRT725239 PDE1B phosphodiesterase 1B 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-2117 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miR-2117 Ascorbate approved 54670067 Microarray Metastatic melanoma cell lines 25202679 2014 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-2117 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM43)
hsa-miR-2117 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-2117 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-2117 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

Error report submission