miRTarBase - #MIRT512505


—
pre-miRNA Information
pre-miRNA hsa-mir-4291   
Genomic Coordinates chr9: 93819357 - 93819421
Description Homo sapiens miR-4291 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4291
Sequence 11| UUCAGCAGGAACAGCU |26
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1265713434 9 dbSNP
rs1433969451 12 dbSNP
rs1372852268 16 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BTBD19   
Synonyms -
Description BTB domain containing 19
Transcript NM_001136537   
Expression
Putative miRNA Targets on BTBD19
3'UTR of BTBD19
(miRNA target sites are highlighted)		 
>BTBD19|NM_001136537|3'UTR
   1 TCCAACGCCGGGACTCGCAGGGAGCCCTCGACCCGCCCAGCTGAGCCTGCCCCAAACTACAGCTCCCGAAGTGCTCGGCG
  81 TTCGGAGCGGGCTTCCGTTCCCAGCGTGCCCAGTGAGCCGGGCGCCGGAAGAACCGTTGTCTGCCACGCGCAGCCCCTTG
 161 TGCGGGATCAAGCCCGTGTGGGCGAGGTGGGGTCGGGCCGGGCAGGGCTTGGGCTGGGCCTCCCTGAGGGGGTGAAACTC
 241 GAAAACGAGGATTTCCTTCGTTCCACACCCTGACTCTACGCCCTGCCCCTGGGCATTGTCGTCTACTAGTCTATTCTGAT
 321 GACTCCCACATATCTATCTGTTCAGCTCAGCTCCCTC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucgacaaGGACGACUu 5'
                 || ||||| 
Target 5' gacccgcCCAGCTGAg 3'
 30 - 45 113.00 -8.30
2 
miRNA  3' ucgACAAGGACGACUu 5'
             | | :|||:| | 
Target 5' ataTCTATCTGTTCAg 3'
 330 - 345 97.00 -6.53
3 
miRNA  3' ucGACAA-GGACGacuu 5'
            | ||| :||||    
Target 5' aaCCGTTGTCTGCcacg 3'
 132 - 148 90.00 -5.76
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30143233 6 COSMIC
COSN20713514 116 COSMIC
COSN30528554 350 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs888429648 4 dbSNP
rs532714371 6 dbSNP
rs1005572989 9 dbSNP
rs1216540741 10 dbSNP
rs552343595 11 dbSNP
rs762061356 12 dbSNP
rs1040434822 13 dbSNP
rs1202462932 16 dbSNP
rs1300935494 17 dbSNP
rs901027146 18 dbSNP
rs1469708375 19 dbSNP
rs1037256238 24 dbSNP
rs1405154868 28 dbSNP
rs1284713884 31 dbSNP
rs1164575463 32 dbSNP
rs868350119 34 dbSNP
rs1394235521 35 dbSNP
rs1476864858 39 dbSNP
rs1169253211 44 dbSNP
rs1448144467 50 dbSNP
rs565942881 50 dbSNP
rs1261798436 64 dbSNP
rs1028199152 68 dbSNP
rs373795892 73 dbSNP
rs554796209 76 dbSNP
rs568331873 77 dbSNP
rs1030243297 79 dbSNP
rs954272840 83 dbSNP
rs1327016711 87 dbSNP
rs1033081259 89 dbSNP
rs368986942 90 dbSNP
rs1032747726 97 dbSNP
rs1426883491 103 dbSNP
rs1213477742 106 dbSNP
rs1388701502 110 dbSNP
rs988987630 114 dbSNP
rs1476013958 117 dbSNP
rs1375325441 119 dbSNP
rs1280552981 124 dbSNP
rs957012516 126 dbSNP
rs988450326 127 dbSNP
rs1479181337 128 dbSNP
rs370918173 136 dbSNP
rs1436890518 137 dbSNP
rs913108930 142 dbSNP
rs773033431 146 dbSNP
rs1222770524 150 dbSNP
rs1490758956 152 dbSNP
rs971718150 154 dbSNP
rs1339962043 157 dbSNP
rs1271892644 158 dbSNP
rs981415842 160 dbSNP
rs927105760 165 dbSNP
rs980261304 168 dbSNP
rs537463533 173 dbSNP
rs1192912226 174 dbSNP
rs570753256 176 dbSNP
rs1328562780 177 dbSNP
rs1393207718 179 dbSNP
rs1055189677 191 dbSNP
rs1399196211 199 dbSNP
rs539782439 200 dbSNP
rs930868548 200 dbSNP
rs941306501 201 dbSNP
rs117344385 205 dbSNP
rs1481202781 211 dbSNP
rs907884294 211 dbSNP
rs1180777909 212 dbSNP
rs1438207634 215 dbSNP
rs940672280 216 dbSNP
rs897195993 217 dbSNP
rs573076170 223 dbSNP
rs370243473 224 dbSNP
rs901897460 228 dbSNP
rs1239679780 229 dbSNP
rs998838187 230 dbSNP
rs1356344316 233 dbSNP
rs1049543415 241 dbSNP
rs1051381842 241 dbSNP
rs1279209200 242 dbSNP
rs889731632 242 dbSNP
rs1337902623 247 dbSNP
rs1000505513 249 dbSNP
rs1443040989 251 dbSNP
rs1176486609 253 dbSNP
rs541530291 260 dbSNP
rs889934163 261 dbSNP
rs11584031 273 dbSNP
rs1405285977 274 dbSNP
rs1157650954 283 dbSNP
rs1304602236 288 dbSNP
rs1234391704 289 dbSNP
rs1032695034 290 dbSNP
rs1460792319 294 dbSNP
rs1243707354 297 dbSNP
rs1205585726 302 dbSNP
rs1193709375 303 dbSNP
rs1283742334 306 dbSNP
rs201181299 306 dbSNP
rs371648956 306 dbSNP
rs1024099486 307 dbSNP
rs575278064 316 dbSNP
rs1251015676 317 dbSNP
rs544173081 331 dbSNP
rs1339298871 334 dbSNP
rs1034498225 337 dbSNP
rs1342932848 338 dbSNP
rs1009980179 345 dbSNP
rs985459621 350 dbSNP
rs1474337478 351 dbSNP
rs1020362643 352 dbSNP
rs1166312541 356 dbSNP
rs1161395590 360 dbSNP
rs1443800494 361 dbSNP
rs58285160 367 dbSNP
rs1185349028 369 dbSNP
rs1216655549 369 dbSNP
rs1241577102 369 dbSNP
rs1444328291 369 dbSNP
rs1484888861 369 dbSNP
rs57491062 369 dbSNP
rs11211038 370 dbSNP
rs1245642768 371 dbSNP
rs192141172 371 dbSNP
rs1360635779 373 dbSNP
rs1213319600 375 dbSNP
rs1317700795 375 dbSNP
rs1360726766 375 dbSNP
rs768694186 375 dbSNP
rs1214585345 377 dbSNP
rs1296946482 377 dbSNP
rs1307386194 377 dbSNP
rs1341836804 377 dbSNP
rs1362008368 377 dbSNP
rs1454997647 377 dbSNP
rs1490594513 377 dbSNP
rs768702217 377 dbSNP
rs867069449 377 dbSNP
rs1466173520 378 dbSNP
rs60343664 378 dbSNP
rs1295043422 379 dbSNP
rs1403932616 379 dbSNP
rs958497004 379 dbSNP
rs1171080532 381 dbSNP
rs1353809126 381 dbSNP
rs546092399 381 dbSNP
rs984627544 382 dbSNP
rs1427287914 383 dbSNP
rs773819353 383 dbSNP
rs1480874222 384 dbSNP
rs1252333701 385 dbSNP
rs1480517758 385 dbSNP
rs759514735 385 dbSNP
rs909927132 385 dbSNP
rs1207237637 386 dbSNP
rs1222411166 387 dbSNP
rs1260676902 387 dbSNP
rs1322104558 387 dbSNP
rs1345709446 387 dbSNP
rs1298602880 389 dbSNP
rs1403879859 389 dbSNP
rs1448890783 389 dbSNP
rs879548612 389 dbSNP
rs941425943 389 dbSNP
rs1175762540 391 dbSNP
rs1491074611 391 dbSNP
rs879623850 391 dbSNP
rs1157199318 392 dbSNP
rs1379527941 392 dbSNP
rs1418785260 392 dbSNP
rs113223337 393 dbSNP
rs1460344168 393 dbSNP
rs1243107250 395 dbSNP
rs1202435972 396 dbSNP
rs1236428371 397 dbSNP
rs1257328222 397 dbSNP
rs148061166 397 dbSNP
rs1316030147 399 dbSNP
rs1242104754 400 dbSNP
rs1336015499 400 dbSNP
rs1404435325 401 dbSNP
rs1453292147 401 dbSNP
rs200696633 401 dbSNP
rs528701709 401 dbSNP
rs1160779146 403 dbSNP
rs1364637211 403 dbSNP
rs934032594 404 dbSNP
rs1444705230 405 dbSNP
rs1491101431 405 dbSNP
rs565005455 405 dbSNP
rs1491254709 406 dbSNP
rs1202905070 407 dbSNP
rs976052419 407 dbSNP
rs1246601366 408 dbSNP
rs1314196854 408 dbSNP
rs1381750293 409 dbSNP
rs1385886136 409 dbSNP
rs1491279166 409 dbSNP
rs890057856 409 dbSNP
rs1491304402 410 dbSNP
rs1365338885 411 dbSNP
rs1423061954 411 dbSNP
rs1474047231 411 dbSNP
rs1491129335 411 dbSNP
rs1491321084 412 dbSNP
rs1392441057 413 dbSNP
rs763608180 413 dbSNP
rs942838316 413 dbSNP
rs1427421983 414 dbSNP
rs866405626 414 dbSNP
rs1210250085 415 dbSNP
rs1263368228 415 dbSNP
rs1290725927 415 dbSNP
rs1249564903 417 dbSNP
rs372685600 417 dbSNP
rs1226711381 418 dbSNP
rs758978592 418 dbSNP
rs772980155 419 dbSNP
rs893339517 419 dbSNP
rs1195271959 420 dbSNP
rs1479232257 420 dbSNP
rs1199240785 421 dbSNP
rs1453129163 421 dbSNP
rs367681598 421 dbSNP
rs1270720009 422 dbSNP
rs1491214956 422 dbSNP
rs1328671249 423 dbSNP
rs1334345903 423 dbSNP
rs1438968091 423 dbSNP
rs775688426 423 dbSNP
rs1392457698 424 dbSNP
rs1403133967 424 dbSNP
rs1180888502 425 dbSNP
rs1230953942 425 dbSNP
rs1467792851 425 dbSNP
rs548537279 425 dbSNP
rs57634867 426 dbSNP
rs1221140526 427 dbSNP
rs1279302702 427 dbSNP
rs1279503617 427 dbSNP
rs1348870781 427 dbSNP
rs923391776 427 dbSNP
rs1241362570 429 dbSNP
rs1244920964 429 dbSNP
rs1334312678 429 dbSNP
rs1335330144 429 dbSNP
rs1238103712 431 dbSNP
rs1309671605 431 dbSNP
rs1405393424 431 dbSNP
rs1415803077 431 dbSNP
rs1212385705 432 dbSNP
rs1445452010 432 dbSNP
rs1283846935 433 dbSNP
rs1313465487 433 dbSNP
rs1356297328 433 dbSNP
rs766196624 433 dbSNP
rs1161494088 435 dbSNP
rs1245870697 435 dbSNP
rs1297217318 435 dbSNP
rs1362204201 435 dbSNP
rs1443895449 435 dbSNP
rs1491475823 435 dbSNP
rs866722227 435 dbSNP
rs1491454409 436 dbSNP
rs1183620697 437 dbSNP
rs1241673268 437 dbSNP
rs1474473964 437 dbSNP
rs71587724 438 dbSNP
rs1194652650 439 dbSNP
rs1222272182 439 dbSNP
rs1292671373 439 dbSNP
rs1318552951 439 dbSNP
rs1491395163 439 dbSNP
rs867518872 439 dbSNP
rs1491177647 440 dbSNP
rs759782134 441 dbSNP
rs796749305 441 dbSNP
rs866198352 441 dbSNP
rs1443717602 442 dbSNP
rs61411780 443 dbSNP
rs1237137377 445 dbSNP
rs59529471 445 dbSNP
rs1327237263 446 dbSNP
rs1408201533 447 dbSNP
rs1418880926 449 dbSNP
rs1194543201 450 dbSNP
rs1326192806 452 dbSNP
rs749868852 453 dbSNP
rs759557483 453 dbSNP
rs764388754 453 dbSNP
rs865871567 453 dbSNP
rs1489019506 454 dbSNP
rs530951127 455 dbSNP
rs113290937 456 dbSNP
rs1203033601 456 dbSNP
rs1307471171 456 dbSNP
rs1368033259 456 dbSNP
rs1385943064 456 dbSNP
rs1295132227 457 dbSNP
rs990688445 457 dbSNP
rs1225711669 458 dbSNP
rs1491072984 459 dbSNP
rs764599840 459 dbSNP
rs754222077 460 dbSNP
rs915067911 460 dbSNP
rs1171430347 461 dbSNP
rs1483578770 461 dbSNP
rs1271504167 462 dbSNP
rs1205659842 463 dbSNP
rs1453406823 464 dbSNP
rs1461290386 464 dbSNP
rs1339693075 466 dbSNP
rs1232098056 467 dbSNP
rs1270705035 468 dbSNP
rs1469449735 470 dbSNP
rs1214232352 472 dbSNP
rs932057450 473 dbSNP
rs1175888002 474 dbSNP
rs1198658275 475 dbSNP
rs1260975159 475 dbSNP
rs1458714750 475 dbSNP
rs1417765207 476 dbSNP
rs767886681 476 dbSNP
rs776974349 476 dbSNP
rs1303100957 480 dbSNP
rs1336126859 480 dbSNP
rs1221894856 482 dbSNP
rs12075002 484 dbSNP
rs1244014423 485 dbSNP
rs1449005533 489 dbSNP
rs1478260040 491 dbSNP
rs1164535109 497 dbSNP
rs1415769442 501 dbSNP
rs1466715344 502 dbSNP
rs1181043249 503 dbSNP
rs1439486035 503 dbSNP
rs530383195 503 dbSNP
rs754529045 503 dbSNP
rs761839030 503 dbSNP
rs1020055452 512 dbSNP
rs1240706281 525 dbSNP
rs1199430494 528 dbSNP
rs1049574998 529 dbSNP
rs911073867 529 dbSNP
rs1213315557 536 dbSNP
rs1352723246 537 dbSNP
rs184315529 541 dbSNP
rs1309798158 543 dbSNP
rs1242212709 545 dbSNP
rs1380541950 547 dbSNP
rs1312042899 548 dbSNP
rs1396698102 552 dbSNP
rs150820653 557 dbSNP
rs1419396138 560 dbSNP
rs1002554981 565 dbSNP
rs1160871616 567 dbSNP
rs1423259261 569 dbSNP
rs1368431844 573 dbSNP
rs1186170053 579 dbSNP
rs539695379 585 dbSNP
rs958612504 587 dbSNP
rs1320716381 595 dbSNP
rs1327438874 601 dbSNP
rs984746976 604 dbSNP
rs1291127986 608 dbSNP
rs1487791713 616 dbSNP
rs139268765 617 dbSNP
rs1233370792 627 dbSNP
rs1218558011 629 dbSNP
rs1260034838 630 dbSNP
rs1348485717 631 dbSNP
rs1206880680 637 dbSNP
rs1342337818 645 dbSNP
rs1293594173 649 dbSNP
rs1399606531 650 dbSNP
rs546699107 650 dbSNP
rs566514277 651 dbSNP
rs1403515072 661 dbSNP
rs1485262915 662 dbSNP
rs544195587 663 dbSNP
rs1255680340 664 dbSNP
rs1045410548 666 dbSNP
rs1476187886 669 dbSNP
rs1369684278 671 dbSNP
rs12089112 673 dbSNP
rs1363677293 674 dbSNP
rs1263480716 676 dbSNP
rs1452233999 677 dbSNP
rs1160844287 681 dbSNP
rs1361567541 683 dbSNP
rs555300678 685 dbSNP
rs1310625636 689 dbSNP
rs1358442379 690 dbSNP
rs1001303540 692 dbSNP
rs1357006607 693 dbSNP
rs1396055816 698 dbSNP
rs1305642113 701 dbSNP
rs1333517337 702 dbSNP
rs1218128328 704 dbSNP
rs1318814910 710 dbSNP
rs1280351226 720 dbSNP
rs1034069942 723 dbSNP
rs1330883549 729 dbSNP
rs1324692771 735 dbSNP
rs1389013930 737 dbSNP
rs1395021455 741 dbSNP
rs1328624973 742 dbSNP
rs1464658231 746 dbSNP
rs952319517 752 dbSNP
rs1006350815 754 dbSNP
rs386630833 761 dbSNP
rs1346813989 767 dbSNP
rs751937272 769 dbSNP
rs1208476616 773 dbSNP
rs1278414511 774 dbSNP
rs1486790875 778 dbSNP
rs1453211847 779 dbSNP
rs1015633169 781 dbSNP
rs1217679557 782 dbSNP
rs1235166814 782 dbSNP
rs1344642839 782 dbSNP
rs71674935 782 dbSNP
rs1275781863 787 dbSNP
rs1235915104 788 dbSNP
rs1333842664 800 dbSNP
rs1249872727 801 dbSNP
rs1417477150 802 dbSNP
rs1309173201 804 dbSNP
rs1448248599 804 dbSNP
rs1400374593 805 dbSNP
rs1332848534 809 dbSNP
rs1184585281 815 dbSNP
rs1381476918 817 dbSNP
rs1454077173 821 dbSNP
rs1401090645 823 dbSNP
rs1172897916 832 dbSNP
rs1478895176 835 dbSNP
rs1378336898 844 dbSNP
rs1441232262 845 dbSNP
rs1279985821 848 dbSNP
rs1240083093 850 dbSNP
rs1208163888 855 dbSNP
rs1466201639 859 dbSNP
rs1297315938 863 dbSNP
rs1202471876 864 dbSNP
rs1393671038 867 dbSNP
rs1351951089 874 dbSNP
rs1309058068 875 dbSNP
rs1241478162 891 dbSNP
rs962313083 894 dbSNP
rs1392644863 896 dbSNP
rs1280745542 909 dbSNP
rs961902341 916 dbSNP
rs973211601 919 dbSNP
rs918698012 924 dbSNP
rs933957630 926 dbSNP
rs1334406667 927 dbSNP
rs1415885402 929 dbSNP
rs1358382026 933 dbSNP
rs1157882362 938 dbSNP
rs762733247 939 dbSNP
rs1382133978 940 dbSNP
rs953358841 941 dbSNP
rs188713113 942 dbSNP
rs563824180 943 dbSNP
rs1348375230 948 dbSNP
rs1234232536 956 dbSNP
rs1251026108 962 dbSNP
rs181092721 970 dbSNP
rs925359899 974 dbSNP
rs911436101 975 dbSNP
rs1285717363 979 dbSNP
rs1197661598 980 dbSNP
rs1239268155 982 dbSNP
rs1217846132 988 dbSNP
rs935870904 1002 dbSNP
rs1468409584 1003 dbSNP
rs1226053842 1006 dbSNP
rs557285360 1008 dbSNP
rs1397263967 1013 dbSNP
rs1054664440 1016 dbSNP
rs1284338139 1021 dbSNP
rs893286966 1024 dbSNP
rs755353553 1025 dbSNP
rs577241963 1029 dbSNP
rs764530064 1034 dbSNP
rs1041829225 1035 dbSNP
rs906958216 1036 dbSNP
rs1463038110 1051 dbSNP
rs1162590328 1056 dbSNP
rs1404747672 1058 dbSNP
rs1414593868 1062 dbSNP
rs751996251 1066 dbSNP
rs945926629 1067 dbSNP
rs1045653860 1068 dbSNP
rs1489478779 1070 dbSNP
rs906880132 1072 dbSNP
rs1438588109 1073 dbSNP
rs1034014368 1079 dbSNP
rs936956001 1086 dbSNP
rs1055556237 1089 dbSNP
rs894182537 1106 dbSNP
rs1277183200 1109 dbSNP
rs887533318 1110 dbSNP
rs1291615906 1123 dbSNP
rs1350430191 1153 dbSNP
rs1006132489 1156 dbSNP
rs147277137 1157 dbSNP
rs1295075100 1159 dbSNP
rs961852198 1160 dbSNP
rs1171648426 1162 dbSNP
rs898097616 1162 dbSNP
rs1478958641 1165 dbSNP
rs1423476966 1168 dbSNP
rs997744758 1184 dbSNP
rs971936983 1187 dbSNP
rs1214953868 1188 dbSNP
rs777590296 1192 dbSNP
rs1030512421 1193 dbSNP
rs1198853098 1194 dbSNP
rs1220744004 1198 dbSNP
rs955486750 1199 dbSNP
rs549148783 1201 dbSNP
rs953389907 1214 dbSNP
rs1212349185 1215 dbSNP
rs911209307 1217 dbSNP
rs986089795 1218 dbSNP
rs1399628870 1224 dbSNP
rs184438502 1229 dbSNP
rs990337601 1230 dbSNP
rs958133103 1237 dbSNP
rs1259173470 1244 dbSNP
rs140881643 1260 dbSNP
rs1429907515 1261 dbSNP
rs542408647 1262 dbSNP
rs1397343431 1263 dbSNP
rs115997047 1265 dbSNP
rs946171216 1266 dbSNP
rs1041889259 1268 dbSNP
rs1236996913 1282 dbSNP
rs1198760651 1286 dbSNP
rs913082789 1290 dbSNP
rs945833492 1300 dbSNP
rs1253894412 1305 dbSNP
rs1209080930 1315 dbSNP
rs928833997 1340 dbSNP
rs780251422 1342 dbSNP
rs528678435 1343 dbSNP
rs574775909 1359 dbSNP
rs1282276126 1361 dbSNP
rs1166939721 1362 dbSNP
rs928495998 1370 dbSNP
rs1429706027 1371 dbSNP
rs1286876075 1372 dbSNP
rs530992612 1373 dbSNP
rs1393242796 1376 dbSNP
rs1377181055 1379 dbSNP
rs1302493430 1380 dbSNP
rs894129958 1401 dbSNP
rs1005911220 1405 dbSNP
rs551095253 1406 dbSNP
rs1037595245 1412 dbSNP
rs1354832039 1413 dbSNP
rs897754319 1414 dbSNP
rs1055458422 1420 dbSNP
rs1322880041 1423 dbSNP
rs1181829892 1427 dbSNP
rs1215769608 1431 dbSNP
rs1253546010 1451 dbSNP
rs1180912085 1454 dbSNP
rs993697910 1455 dbSNP
rs768918158 1475 dbSNP
rs1030161994 1483 dbSNP
rs1286670702 1488 dbSNP
rs1259302900 1497 dbSNP
rs1489514842 1502 dbSNP
rs551545105 1507 dbSNP
rs564443098 1509 dbSNP
rs1396789827 1517 dbSNP
rs1357632194 1524 dbSNP
rs1018331185 1527 dbSNP
rs963983676 1531 dbSNP
rs189324193 1545 dbSNP
rs1030545171 1548 dbSNP
rs914785438 1554 dbSNP
rs1256386473 1563 dbSNP
rs967651072 1569 dbSNP
rs551966080 1575 dbSNP
rs1475308225 1579 dbSNP
rs978109850 1585 dbSNP
rs868172165 1590 dbSNP
rs1032323795 1601 dbSNP
rs144829556 1610 dbSNP
rs938875014 1622 dbSNP
rs988255872 1631 dbSNP
rs182263643 1637 dbSNP
rs1400009436 1645 dbSNP
rs1021423829 1649 dbSNP
rs746809091 1650 dbSNP
rs535428914 1656 dbSNP
rs1337149047 1658 dbSNP
rs1346730143 1667 dbSNP
rs915678396 1670 dbSNP
rs1420092637 1671 dbSNP
rs1298957259 1673 dbSNP
rs1355103831 1686 dbSNP
rs1385564219 1686 dbSNP
rs941643292 1687 dbSNP
rs1292388991 1695 dbSNP
rs1461523572 1697 dbSNP
rs1419491636 1698 dbSNP
rs1168093899 1702 dbSNP
rs1477317493 1707 dbSNP
rs1412964626 1713 dbSNP
rs145840011 1715 dbSNP
rs1195096142 1727 dbSNP
rs1431318925 1731 dbSNP
rs1266603304 1734 dbSNP
rs897525992 1738 dbSNP
rs1214326031 1740 dbSNP
rs568960849 1742 dbSNP
rs1223711906 1743 dbSNP
rs937229382 1745 dbSNP
rs1340371135 1757 dbSNP
rs1272251300 1762 dbSNP
rs1330975427 1769 dbSNP
rs149003906 1769 dbSNP
rs557447477 1788 dbSNP
rs1356229043 1791 dbSNP
rs1396021519 1793 dbSNP
rs908898202 1800 dbSNP
rs112309146 1802 dbSNP
rs1396790938 1802 dbSNP
rs1464359907 1802 dbSNP
rs375079087 1802 dbSNP
rs941665103 1802 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 149478.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucgacaaGGACGACUu 5'
                 |||||||| 
Target 5' acuucagCCUGCUGAa 3'
 		1 - 16
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000453418.1 | 3UTR | ACUUCAGCCUGCUGAAUAGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
82 hsa-miR-4291 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102445 CALU calumenin 2 4
MIRT108677 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT125969 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT179018 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT379033 CDK6 cyclin dependent kinase 6 2 6
MIRT442473 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 2
MIRT442910 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT442979 ZNF736 zinc finger protein 736 2 2
MIRT445663 TNFSF15 TNF superfamily member 15 2 2
MIRT446237 FZD6 frizzled class receptor 6 2 2
MIRT448860 FAM49B family with sequence similarity 49 member B 2 2
MIRT455559 TRAF1 TNF receptor associated factor 1 2 2
MIRT459704 ZNF641 zinc finger protein 641 2 2
MIRT460608 FEM1A fem-1 homolog A 2 2
MIRT462251 LAMA4 laminin subunit alpha 4 2 2
MIRT462469 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT466656 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 6
MIRT466841 STX6 syntaxin 6 2 2
MIRT471403 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT471517 PCGF3 polycomb group ring finger 3 2 2
MIRT471681 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT472858 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT474813 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT474931 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475814 HDGF heparin binding growth factor 2 2
MIRT480434 C17orf49 chromosome 17 open reading frame 49 2 2
MIRT480903 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT481478 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT484982 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT485019 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT485036 TMEM189 transmembrane protein 189 2 8
MIRT495074 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT496004 CD180 CD180 molecule 2 2
MIRT500675 TRIM37 tripartite motif containing 37 2 2
MIRT504544 ZNF417 zinc finger protein 417 2 6
MIRT506782 KLHL15 kelch like family member 15 2 6
MIRT507256 FGF2 fibroblast growth factor 2 2 6
MIRT507386 EN2 engrailed homeobox 2 2 2
MIRT512505 BTBD19 BTB domain containing 19 2 2
MIRT516903 CTSB cathepsin B 2 2
MIRT528124 PPP1R10 protein phosphatase 1 regulatory subunit 10 2 2
MIRT528874 ATF3 activating transcription factor 3 2 2
MIRT536091 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT541079 RLIM ring finger protein, LIM domain interacting 2 2
MIRT541099 RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2 2
MIRT545360 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT545831 ZNF367 zinc finger protein 367 2 4
MIRT547115 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT547312 NPTN neuroplastin 2 2
MIRT547959 HIGD1A HIG1 hypoxia inducible domain family member 1A 2 4
MIRT549943 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT550749 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT565145 TUBB2A tubulin beta 2A class IIa 2 2
MIRT571050 POLQ DNA polymerase theta 2 2
MIRT571361 ZNF45 zinc finger protein 45 2 2
MIRT610133 FOXI2 forkhead box I2 2 2
MIRT613145 DSE dermatan sulfate epimerase 2 2
MIRT613379 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT615752 C6 complement C6 2 2
MIRT616460 ADRA2B adrenoceptor alpha 2B 2 2
MIRT616719 FEM1B fem-1 homolog B 2 2
MIRT618312 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT631491 RASSF4 Ras association domain family member 4 2 2
MIRT643134 PLCXD2 phosphatidylinositol specific phospholipase C X domain containing 2 2 2
MIRT643482 DISC1 disrupted in schizophrenia 1 2 2
MIRT649715 TWSG1 twisted gastrulation BMP signaling modulator 1 2 2
MIRT653542 SLC38A7 solute carrier family 38 member 7 2 2
MIRT666307 SLC22A3 solute carrier family 22 member 3 2 2
MIRT692005 NAP1L4 nucleosome assembly protein 1 like 4 2 2
MIRT696838 ARL2BP ADP ribosylation factor like GTPase 2 binding protein 2 2
MIRT698204 TMEM248 transmembrane protein 248 2 2
MIRT703316 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT709376 FAM13A family with sequence similarity 13 member A 2 2
MIRT710112 MED23 mediator complex subunit 23 2 2
MIRT711975 HOMER2 homer scaffolding protein 2 2 2
MIRT712275 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT714108 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT719113 MAML1 mastermind like transcriptional coactivator 1 2 2
MIRT719727 SLC39A11 solute carrier family 39 member 11 2 2
MIRT720018 TFAP2C transcription factor AP-2 gamma 2 2
MIRT720358 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT720372 NUDT3 nudix hydrolase 3 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4291 Platinum-based doublet chemotherapy resistant High Lung Adenocarcinoma tissue
hsa-miR-4291 Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-4291 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-4291 Doxorubicin 31703 NSC123127 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-4291 Radioactivity Iodine resistant High Papillary Thyroid Cancer tissue
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-4291 Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4291 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-4291 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4291 Platinum-based doublet chemotherapy resistant tissue (lung adenocarcinoma)
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4291 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR3)
hsa-miR-4291 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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