miRTarBase - #MIRT512528


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pre-miRNA Information
pre-miRNA hsa-mir-3663   
Genomic Coordinates chr10: 117167678 - 117167774
Description Homo sapiens miR-3663 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3663-5p
Sequence 21| GCUGGUCUGCGUGGUGCUCGG |41
Evidence Experimental
Experiments Northern
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs111525499 10 dbSNP
rs1186183324 11 dbSNP
rs1166397684 12 dbSNP
rs1391472885 17 dbSNP
rs1461514502 20 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ATCAY   
Synonyms BNIP-H, CLAC
Description ATCAY, caytaxin
Transcript NM_033064   
Expression
Putative miRNA Targets on ATCAY
3'UTR of ATCAY
(miRNA target sites are highlighted)		 
>ATCAY|NM_033064|3'UTR
   1 GGCGACGTGAGCATAACAAAGGACATGGAAGAAGATTCCAGATGCCAGAAAACCTCTGTCAGACGCCCACTGGCCCCAGA
  81 TCTCATCCTGCCTCATCCTGAGTCCCAATCTTCCAAGGGTGCCAGCCCCTCCGTTCATCTCTGAAACCCAGCATCCTTTT
 161 CAGCTGCTTGAAAACATTGTATTTTTTTTTTTTAACGATGCAGTATTTGTGCGTTCCAGAAAAGGGCCCAGCTCTGAGCC
 241 CCTCACCCTTCCACACTCACGAACTCTCAGCCGAGGAAGGCAAGAAGCGCAGGGGGTGGCCCGCGTGGCGTCGGTGGCCT
 321 CCGCTCCTGCTCGCAGCCCCTGTGGTCAGAGCTGGATACAAGATTCAAGACCCTTCTCTTGCTTGTCACCCGCTCCAGGT
 401 TGGAGCCACAGACACCCACCGCCACCCCGGCTGGGTCTGCGTCCTTTCCTGTGCCTTTCCCTCCAGAATGCGGCCTCAGA
 481 CCTAGAAGCTCAACCCCCCTATGAGGGCCACGTCCTGGGGTAGCTCCTGACCTCCGACCTTATGTCCAAATTTCACACCC
 561 ATGGTTTTTCATTTGACCCGCCCCCTTCTCGCTCATAATGACACCCAGCTCCTTTGAGAGGATCAGAGCCCATTGCACAA
 641 GAAGAGCCGCTGCCAACCATCCTTGTCCTCCGATTGCAAAATGACACCCCAGTAATCTAGAACATTCTCAAGCCCCTTTA
 721 ACTCAGATGTCAAGCCACCGGGCAAACCCCGTCAATACCTCCCACCAAGGAATGAGATATGTGGACCTCACTGCTCCCCC
 801 AACCCAGCGTCAGGCTGGGACACGCCAACGCTGTTCCGGGTTGGAACAGCAGAGGCTCAGAAACTGGCTCTGAAATAGGC
 881 AGACCTAGCAAGAGGAAGATACAGGGTATCGGGCGTTTGAGTGTTTCAGAAGTCATTCGGGAAGATAAATCCAGTGCGCT
 961 GGCCGCAGCCACCTGCATTCAAAGCTTGGACCAGCGGGTTCTTGTTCGGGAGGCAAATTTCCCTAGGAAAAAGAAGACAG
1041 ACTTTTCTAATGTGGTCCAAATGCGGATCACTGGTCAGATGGACTCTAGAAGCACTGAGCTCCCTGTCTCTGGAAGTATT
1121 TAAGAAAAGGCTGGGCCAGGCACGATGGCTCACGCCTGTAATCCCAGACTTTGGGAGGCCGAGGCAGGCGGATCACCTGA
1201 GGTGAGGAGTTTGAGAACAGCCTGGCCAACATGGTGAAACCTCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGT
1281 GGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCATGAGAATCACTTAAACCTGAGAGGCAGAGGTTACAGTGA
1361 GCCAAGATCGTGCCACTGCATTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTCAAAAAAAATAAAAAATAATCAGGGCA
1441 CAGTGGCTCATGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGC
1521 CTGGTGAACATGGCGAAACCCCGTCTCTAATAAAAATACAAAAATTAGCCGGGCATGGTGGTGCATGCCTGTAATCCCAG
1601 CTACTCGGGAGGCTGAGGCAGGAGAACTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGATCCAAGATCATGCCACTGCAC
1681 TCCAGCCTGGGCAACAAGAGCAAAACTCCGTCTCAAAATAAAAAGAAAAGAAAAGAATGGACAGTGTTTGCAGAGAGTTG
1761 CTCACGAGTTTCCCTCTAATCCTAAATGTCTTCATGTCTATCAGTCTGAGCAGACGGTGAGTAGGGCGGGCACATTCTCC
1841 AGGCCCTTCTTCCTAGCTCTGTGGTTGACCTCTCAGCAAGTGCTATCCAGGCTGGGCCAACCAGACCCACAATTAACTGA
1921 GCCTCAGTGAAAGCGTCCAGTGCATCTTGACCTGAGACAGCAAGGAATTGCATTTGGGGTTATTCCAACGATGATGGCAG
2001 GGAACTGGTGGTATTTAGTGCTGAGGGGCAGTGATACAGAAAGATTTGCCCTGTGGGACAGGGTCCTGCGCGAGTCCCAT
2081 CCCCAAAAGCCAGCAGCTCCTGCCATGAGGAAGACGGGGTTTCTGAGCAGGCTTATGCCTGCAGGTTCCTGTGGAGCCAC
2161 CGGCTGTGACGGGACACCTCTGGGTCTCAGCATTGCCCTGGGGAGGCTGGGACATTTAGGGACATGGTAGGGTTTTAACA
2241 TTTGTTTCCCAAATGTCAAATCCCGGGCACAGGGGCAAGACCCTGTCCCGAATTCCCACCCCAGTGAATGGTGTCGCTGC
2321 CAAAGCCAACACAAGATGACAAAAGTGGCTGGGTACGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGACCGAGACA
2401 GGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGGCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAT
2481 TAGCTGGGTGTGGTGGCGCGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGTAGAAGAATAGCTGGAACCCAGGAGGC
2561 AGAGATTGCAGTCAGCCGAGATTGCACCACTGCACTCCAGCCTGGGAGACAGAGCAAGACTGACTCAAAAGAAAAAAAAT
2641 GACAGAAGCCTGATTATCAGACTGCCCGGAGGAGACAGGCTCCAGCAGATAGATGCCAGCCAGGCCCAGCTGCCACGATT
2721 TGTCCCAGGTGACCAAAGGCACGCAGCTCCAGCATGAATCGTTCTAACCCAACAGTGACAAGAACTGCTGGGCCTTAACC
2801 GTCATGGAAGACTGGGGCCGCTTCCAAGTCACAGACAGGAGACGGGGACAGGAAAGAACTCATTCCACCCAATCGGACAC
2881 CTAATAATTGAGTGTCTACAGCAGCAATCAAGTGACAAGTGAGGCCCTACCTGACCCAGAAGGTGCCTGCCGGCTAAACA
2961 TTCTGCCCCCACCAGAAACTCCAGGGGGTCCGCCCGTTATGCCGTGGCCCACCCACGCCCCTTTGGATCACCAGCAGTCA
3041 CAGACAACAGGCAGGCGAAACTGAAGACCCCAACTCAGCCCCAGCGGACCCTCCAGAGCAAAAGAGGCCCCCGGCGAGGC
3121 CACCTGTCGGCAGGCATGCCGAGGTCAAACAGCCGGGGCCACCGTTCCCAGCTGGGCCACGACCTGCACCGTCCACAGAT
3201 GGGCTTTGAGATGGATTTGTATCAGGGTGGGGGGTGTGGTTTGGCCAAAATGCAATGGACCCCGACCCCTCCTCGTAAAA
3281 GGATGTTGGGTTTCCCTCTGGTGACACATGGGATGCGTCATAAACCCTCCCCCAAAGTCCTGGTCAGCAGCCCATCCTTC
3361 CAACGATGAGTTTTGCGGTTTTTCAGAACAGAAATGATCACTACGATTGACGACGGTCGTGATGTTAAGACGTCGTCTCC
3441 ATGAGCTTTGGGGGGACTTTTATGTGGAATAAAGAAACTATCACTGAGAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggcUCGUGGUGCGUCUGGUCg 5'
             || | : || ||||||| 
Target 5' gtcAGGAGTTCG-AGACCAGg 3'
 2416 - 2435 149.00 -16.20
2 
miRNA  3' ggCUCGUGGUGCGUCUGGUCg 5'
            |||: :||   ||||||| 
Target 5' agGAGT-TCA---AGACCAGc 3'
 1504 - 1520 147.00 -16.60
3 
miRNA  3' ggcuCGU-GGU---GCGUCUGGUCg 5'
              ||| :||   | ::|||||| 
Target 5' acctGCATTCAAAGCTTGGACCAGc 3'
 971 - 995 133.00 -17.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
892892 8 ClinVar
892893 27 ClinVar
329154 144 ClinVar
329155 182 ClinVar
329156 182 ClinVar
893706 213 ClinVar
329157 267 ClinVar
893707 310 ClinVar
329158 314 ClinVar
329159 392 ClinVar
893971 392 ClinVar
893972 421 ClinVar
893973 431 ClinVar
329160 442 ClinVar
329161 442 ClinVar
329162 487 ClinVar
329163 497 ClinVar
893974 508 ClinVar
894367 513 ClinVar
894368 600 ClinVar
894369 609 ClinVar
894370 613 ClinVar
329164 682 ClinVar
329165 688 ClinVar
329166 729 ClinVar
329167 741 ClinVar
892926 759 ClinVar
329168 807 ClinVar
329169 814 ClinVar
329170 824 ClinVar
892927 839 ClinVar
892928 872 ClinVar
892929 930 ClinVar
329171 940 ClinVar
893160 959 ClinVar
329172 977 ClinVar
329173 1037 ClinVar
893161 1052 ClinVar
893162 1155 ClinVar
329174 1168 ClinVar
329175 1181 ClinVar
329176 1182 ClinVar
329177 1189 ClinVar
894005 1191 ClinVar
329178 1194 ClinVar
894006 1218 ClinVar
329179 1236 ClinVar
894007 1277 ClinVar
894008 1323 ClinVar
329180 1410 ClinVar
329181 1424 ClinVar
329182 1428 ClinVar
329183 1536 ClinVar
329184 1541 ClinVar
329185 1543 ClinVar
329186 1587 ClinVar
329187 1633 ClinVar
329188 1654 ClinVar
892967 1661 ClinVar
329189 1762 ClinVar
892968 1802 ClinVar
892969 1979 ClinVar
329190 2027 ClinVar
329191 2266 ClinVar
892970 2283 ClinVar
892971 2290 ClinVar
329192 2298 ClinVar
329193 2312 ClinVar
329194 2357 ClinVar
893188 2358 ClinVar
893189 2395 ClinVar
893190 2396 ClinVar
329195 2427 ClinVar
893191 2498 ClinVar
894039 2515 ClinVar
329196 2587 ClinVar
329197 2669 ClinVar
894040 2693 ClinVar
329198 2743 ClinVar
329199 2997 ClinVar
894041 3019 ClinVar
329200 3109 ClinVar
894438 3125 ClinVar
894439 3137 ClinVar
329201 3155 ClinVar
329202 3182 ClinVar
894440 3203 ClinVar
329203 3204 ClinVar
894441 3320 ClinVar
893007 3333 ClinVar
329204 3377 ClinVar
893008 3378 ClinVar
893009 3405 ClinVar
893010 3416 ClinVar
COSN31519078 2 COSMIC
COSN30103532 7 COSMIC
COSN30166944 14 COSMIC
COSN30104053 19 COSMIC
COSN9850090 21 COSMIC
COSN24402955 27 COSMIC
COSN31490788 32 COSMIC
COSN31565386 57 COSMIC
COSN26481863 59 COSMIC
COSN13803542 65 COSMIC
COSN30586102 66 COSMIC
COSN6144043 68 COSMIC
COSN30496791 69 COSMIC
COSN30147697 101 COSMIC
COSN30542627 106 COSMIC
COSN30704732 106 COSMIC
COSN13803544 107 COSMIC
COSN31546516 114 COSMIC
COSN30168565 142 COSMIC
COSN31570517 157 COSMIC
COSN30460270 159 COSMIC
COSN1215359 194 COSMIC
COSN18741988 194 COSMIC
COSN25717286 256 COSMIC
COSN7126500 289 COSMIC
COSN21399747 442 COSMIC
COSN30000514 483 COSMIC
COSN26193582 509 COSMIC
COSN21918164 617 COSMIC
COSN18861860 642 COSMIC
COSN143976 754 COSMIC
COSN21532104 915 COSMIC
COSN25150915 1345 COSMIC
COSN29966817 1414 COSMIC
COSN27074987 1423 COSMIC
COSN9357015 1649 COSMIC
COSN23929740 1654 COSMIC
COSN32072682 1668 COSMIC
COSN21998147 1782 COSMIC
COSN5184498 1814 COSMIC
COSN16518163 2072 COSMIC
COSN7126510 2109 COSMIC
COSN21126793 2281 COSMIC
COSN7126513 2530 COSMIC
COSN1767918 2666 COSMIC
COSN25521482 2802 COSMIC
COSN15661537 2993 COSMIC
COSN9357022 3020 COSMIC
COSN29087279 3058 COSMIC
COSN16008328 3113 COSMIC
COSN1215360 3116 COSMIC
COSN1767920 3232 COSMIC
COSN25852799 3302 COSMIC
rs10412199 3182 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs778013103 4 dbSNP
rs368673244 5 dbSNP
rs1384425556 7 dbSNP
rs60814801 8 dbSNP
rs775351044 12 dbSNP
rs1270081369 16 dbSNP
rs1211190549 22 dbSNP
rs377184300 23 dbSNP
rs1217688525 26 dbSNP
rs190923267 27 dbSNP
rs762628026 28 dbSNP
rs1051687449 29 dbSNP
rs1206684988 40 dbSNP
rs1218812683 61 dbSNP
rs952866701 65 dbSNP
rs1272905341 66 dbSNP
rs373631624 74 dbSNP
rs775932493 84 dbSNP
rs1303232372 89 dbSNP
rs1399378276 93 dbSNP
rs1332337401 101 dbSNP
rs1467418988 107 dbSNP
rs571967208 109 dbSNP
rs1172419909 115 dbSNP
rs1478560550 133 dbSNP
rs1325233751 134 dbSNP
rs537298270 144 dbSNP
rs760798191 150 dbSNP
rs1017635035 167 dbSNP
rs976951221 177 dbSNP
rs922882766 179 dbSNP
rs1198698310 182 dbSNP
rs1276057614 182 dbSNP
rs1321638790 182 dbSNP
rs796133913 182 dbSNP
rs886054416 182 dbSNP
rs1026904126 193 dbSNP
rs1345382595 194 dbSNP
rs935485880 197 dbSNP
rs1052649116 198 dbSNP
rs1376022602 199 dbSNP
rs1310142277 200 dbSNP
rs1449072142 206 dbSNP
rs1216181870 210 dbSNP
rs1338995525 212 dbSNP
rs764132493 213 dbSNP
rs946446277 214 dbSNP
rs1404744293 226 dbSNP
rs1157375440 235 dbSNP
rs1419671704 248 dbSNP
rs1381455130 258 dbSNP
rs754083238 261 dbSNP
rs556134477 262 dbSNP
rs867087852 267 dbSNP
rs1186340050 271 dbSNP
rs990521669 272 dbSNP
rs904830765 273 dbSNP
rs946461588 274 dbSNP
rs1003229063 281 dbSNP
rs1042189481 289 dbSNP
rs1056382108 290 dbSNP
rs1264085923 295 dbSNP
rs897780418 301 dbSNP
rs933901516 303 dbSNP
rs145391309 304 dbSNP
rs1423042186 305 dbSNP
rs1399772954 306 dbSNP
rs1050955385 309 dbSNP
rs541933098 310 dbSNP
rs951980775 311 dbSNP
rs141455019 314 dbSNP
rs1404549432 319 dbSNP
rs899212240 320 dbSNP
rs995340975 322 dbSNP
rs1238834117 323 dbSNP
rs571947244 324 dbSNP
rs1298589333 327 dbSNP
rs1487801581 330 dbSNP
rs1362002804 333 dbSNP
rs1018795666 334 dbSNP
rs1218647449 338 dbSNP
rs4807529 340 dbSNP
rs1289297998 343 dbSNP
rs886590489 346 dbSNP
rs564090132 363 dbSNP
rs577521523 364 dbSNP
rs1276461871 373 dbSNP
rs922847190 374 dbSNP
rs1276974817 382 dbSNP
rs1300621533 386 dbSNP
rs543315185 387 dbSNP
rs765579267 392 dbSNP
rs988799770 393 dbSNP
rs1419578542 399 dbSNP
rs915377888 404 dbSNP
rs1222136828 408 dbSNP
rs946887036 414 dbSNP
rs1044796308 421 dbSNP
rs926383867 422 dbSNP
rs938991361 426 dbSNP
rs1195539299 428 dbSNP
rs1489369101 429 dbSNP
rs1214683213 430 dbSNP
rs866573378 431 dbSNP
rs1222403640 438 dbSNP
rs117035326 442 dbSNP
rs1198200585 455 dbSNP
rs182720083 472 dbSNP
rs923742318 472 dbSNP
rs986634598 473 dbSNP
rs1275892913 482 dbSNP
rs115839391 487 dbSNP
rs1366580385 490 dbSNP
rs886054417 497 dbSNP
rs386806070 498 dbSNP
rs549488844 498 dbSNP
rs116217703 499 dbSNP
rs115537554 500 dbSNP
rs1172348568 500 dbSNP
rs1431163641 502 dbSNP
rs116813246 508 dbSNP
rs1048265088 509 dbSNP
rs1455663149 512 dbSNP
rs964128076 513 dbSNP
rs998137101 519 dbSNP
rs1297177710 530 dbSNP
rs1402553205 531 dbSNP
rs1208467224 532 dbSNP
rs1311918136 533 dbSNP
rs1397198344 536 dbSNP
rs1029577401 537 dbSNP
rs747677795 542 dbSNP
rs886561830 557 dbSNP
rs988381090 559 dbSNP
rs769374138 560 dbSNP
rs1035191690 562 dbSNP
rs1377185983 570 dbSNP
rs1331639177 572 dbSNP
rs915496389 580 dbSNP
rs968226112 581 dbSNP
rs1378390276 586 dbSNP
rs981381769 588 dbSNP
rs1245924361 592 dbSNP
rs1012517145 595 dbSNP
rs1252948361 596 dbSNP
rs571828838 600 dbSNP
rs926357788 609 dbSNP
rs1238455341 612 dbSNP
rs187449912 619 dbSNP
rs1212662533 622 dbSNP
rs1352230892 639 dbSNP
rs1356264005 649 dbSNP
rs1021938889 650 dbSNP
rs192845418 658 dbSNP
rs1353735604 670 dbSNP
rs182922675 672 dbSNP
rs991917466 673 dbSNP
rs772852314 682 dbSNP
rs1031165060 686 dbSNP
rs377406299 688 dbSNP
rs1048955428 693 dbSNP
rs1303271910 694 dbSNP
rs371256803 729 dbSNP
rs1358555225 731 dbSNP
rs943206182 735 dbSNP
rs1157914997 740 dbSNP
rs569661909 741 dbSNP
rs963903128 748 dbSNP
rs1162736425 750 dbSNP
rs1423513343 751 dbSNP
rs1460786717 752 dbSNP
rs116954582 759 dbSNP
rs1487477099 762 dbSNP
rs901688174 769 dbSNP
rs1263126625 781 dbSNP
rs772381257 783 dbSNP
rs1487118203 792 dbSNP
rs1262025775 795 dbSNP
rs1241966174 796 dbSNP
rs1437584503 796 dbSNP
rs1320813244 801 dbSNP
rs1312905844 803 dbSNP
rs777700289 804 dbSNP
rs73919392 807 dbSNP
rs892443818 810 dbSNP
rs886054418 814 dbSNP
rs188380338 815 dbSNP
rs1170249614 819 dbSNP
rs1400832536 821 dbSNP
rs10424392 824 dbSNP
rs1332611132 825 dbSNP
rs968744813 830 dbSNP
rs1369280307 831 dbSNP
rs192312376 837 dbSNP
rs981022218 838 dbSNP
rs1306758402 839 dbSNP
rs1477063042 840 dbSNP
rs1033814014 845 dbSNP
rs764695068 852 dbSNP
rs577732975 854 dbSNP
rs1012446249 856 dbSNP
rs1487841053 861 dbSNP
rs960877149 866 dbSNP
rs1044359536 868 dbSNP
rs1322886240 871 dbSNP
rs183948049 872 dbSNP
rs538453393 872 dbSNP
rs143782200 889 dbSNP
rs1239858579 892 dbSNP
rs919031466 902 dbSNP
rs1328200925 905 dbSNP
rs928971278 908 dbSNP
rs745380946 911 dbSNP
rs1030673906 912 dbSNP
rs1456397540 915 dbSNP
rs984894726 916 dbSNP
rs909131661 923 dbSNP
rs943243926 924 dbSNP
rs1171914108 926 dbSNP
rs1007947890 930 dbSNP
rs1298106315 932 dbSNP
rs1376769943 933 dbSNP
rs1018000611 939 dbSNP
rs886054419 940 dbSNP
rs1194938799 951 dbSNP
rs1456216780 956 dbSNP
rs761998213 958 dbSNP
rs901656902 959 dbSNP
rs1196168910 962 dbSNP
rs933173757 963 dbSNP
rs1051110795 965 dbSNP
rs973968622 966 dbSNP
rs1232489385 972 dbSNP
rs73919393 977 dbSNP
rs1368712739 978 dbSNP
rs1305792744 983 dbSNP
rs574017739 989 dbSNP
rs750732407 996 dbSNP
rs1376443324 997 dbSNP
rs1332229071 1000 dbSNP
rs1388938876 1002 dbSNP
rs1009567905 1008 dbSNP
rs575752493 1009 dbSNP
rs1172328825 1011 dbSNP
rs907888626 1016 dbSNP
rs1022677650 1029 dbSNP
rs1397419178 1031 dbSNP
rs903860922 1036 dbSNP
rs73919394 1037 dbSNP
rs1033948444 1041 dbSNP
rs529349487 1063 dbSNP
rs992354914 1064 dbSNP
rs1237205669 1065 dbSNP
rs1026054137 1066 dbSNP
rs1307058386 1071 dbSNP
rs1253873725 1077 dbSNP
rs1199649063 1079 dbSNP
rs189314913 1092 dbSNP
rs1043902230 1098 dbSNP
rs1238074764 1099 dbSNP
rs984562643 1100 dbSNP
rs908838918 1110 dbSNP
rs964423788 1117 dbSNP
rs974608720 1121 dbSNP
rs904068466 1123 dbSNP
rs1353017080 1125 dbSNP
rs923214985 1130 dbSNP
rs933142462 1140 dbSNP
rs1315942934 1144 dbSNP
rs1444687651 1145 dbSNP
rs1338906985 1149 dbSNP
rs1333991440 1152 dbSNP
rs1052918404 1154 dbSNP
rs528605076 1155 dbSNP
rs1052025319 1157 dbSNP
rs1489330244 1163 dbSNP
rs146859461 1165 dbSNP
rs751398427 1168 dbSNP
rs1267655289 1176 dbSNP
rs1477953268 1177 dbSNP
rs1195155388 1180 dbSNP
rs140608538 1181 dbSNP
rs530991790 1182 dbSNP
rs1002227558 1183 dbSNP
rs1055370811 1187 dbSNP
rs896772959 1188 dbSNP
rs886054420 1189 dbSNP
rs1485842730 1190 dbSNP
rs143684746 1191 dbSNP
rs192536222 1194 dbSNP
rs1026830091 1199 dbSNP
rs1285108567 1203 dbSNP
rs987591578 1204 dbSNP
rs532962627 1205 dbSNP
rs535482434 1211 dbSNP
rs1459765640 1218 dbSNP
rs755691443 1220 dbSNP
rs951346131 1221 dbSNP
rs148116098 1236 dbSNP
rs1357709006 1239 dbSNP
rs964329819 1245 dbSNP
rs1400873424 1258 dbSNP
rs1280377927 1271 dbSNP
rs1338488085 1275 dbSNP
rs1318482548 1276 dbSNP
rs762362391 1276 dbSNP
rs974409532 1277 dbSNP
rs923183757 1280 dbSNP
rs1388148579 1287 dbSNP
rs1323441071 1290 dbSNP
rs954589196 1304 dbSNP
rs988751575 1305 dbSNP
rs1290791880 1308 dbSNP
rs1324018677 1309 dbSNP
rs960684972 1323 dbSNP
rs913027077 1325 dbSNP
rs1218304823 1330 dbSNP
rs992198106 1345 dbSNP
rs947257999 1349 dbSNP
rs1449883004 1352 dbSNP
rs1260657244 1355 dbSNP
rs565298850 1356 dbSNP
rs1044180006 1358 dbSNP
rs1182006097 1360 dbSNP
rs1337192633 1370 dbSNP
rs534430825 1371 dbSNP
rs1218403433 1373 dbSNP
rs1426098833 1382 dbSNP
rs1162012125 1394 dbSNP
rs1384968691 1395 dbSNP
rs1420743581 1397 dbSNP
rs1300260728 1405 dbSNP
rs948170319 1406 dbSNP
rs557406608 1409 dbSNP
rs886054421 1410 dbSNP
rs1396207982 1415 dbSNP
rs979980731 1415 dbSNP
rs777394602 1419 dbSNP
rs925490564 1422 dbSNP
rs935519703 1423 dbSNP
rs184437292 1424 dbSNP
rs891410902 1424 dbSNP
rs1246227710 1425 dbSNP
rs536842684 1428 dbSNP
rs1469999612 1431 dbSNP
rs1256397036 1432 dbSNP
rs557268363 1442 dbSNP
rs376621460 1447 dbSNP
rs899547902 1452 dbSNP
rs189915131 1457 dbSNP
rs748992014 1467 dbSNP
rs1354124689 1472 dbSNP
rs1242129501 1476 dbSNP
rs1440915788 1485 dbSNP
rs553418221 1506 dbSNP
rs1372806998 1520 dbSNP
rs1328852149 1530 dbSNP
rs1027213212 1531 dbSNP
rs886054422 1536 dbSNP
rs140917952 1541 dbSNP
rs10404967 1543 dbSNP
rs1016415622 1544 dbSNP
rs1482011471 1551 dbSNP
rs1455634273 1557 dbSNP
rs959947399 1566 dbSNP
rs565220890 1568 dbSNP
rs992123975 1571 dbSNP
rs531177470 1572 dbSNP
rs1208385544 1574 dbSNP
rs1243127698 1575 dbSNP
rs1440692966 1576 dbSNP
rs1160824143 1577 dbSNP
rs1405996235 1580 dbSNP
rs1400370829 1585 dbSNP
rs10411454 1587 dbSNP
rs1360937313 1592 dbSNP
rs561488764 1597 dbSNP
rs979521685 1598 dbSNP
rs1373541590 1599 dbSNP
rs1450607003 1605 dbSNP
rs530340601 1607 dbSNP
rs797008251 1607 dbSNP
rs1374838726 1608 dbSNP
rs1313388725 1613 dbSNP
rs1377641702 1618 dbSNP
rs989110450 1623 dbSNP
rs1448635505 1625 dbSNP
rs1020223796 1631 dbSNP
rs546859649 1633 dbSNP
rs1419909297 1637 dbSNP
rs1349452639 1650 dbSNP
rs543950349 1654 dbSNP
rs1463951003 1661 dbSNP
rs1280358769 1662 dbSNP
rs978650007 1664 dbSNP
rs1213601163 1665 dbSNP
rs1487568813 1670 dbSNP
rs925353996 1675 dbSNP
rs938035913 1681 dbSNP
rs528060105 1685 dbSNP
rs1237629748 1691 dbSNP
rs990914047 1696 dbSNP
rs551100566 1711 dbSNP
rs1308681896 1716 dbSNP
rs1202555170 1720 dbSNP
rs1226449669 1720 dbSNP
rs912776102 1721 dbSNP
rs944301769 1721 dbSNP
rs949433839 1721 dbSNP
rs1048430137 1722 dbSNP
rs1039316394 1725 dbSNP
rs773660722 1727 dbSNP
rs1475106654 1736 dbSNP
rs760966597 1738 dbSNP
rs930999294 1746 dbSNP
rs1458614727 1747 dbSNP
rs777283516 1762 dbSNP
rs942185904 1766 dbSNP
rs142931322 1767 dbSNP
rs900687123 1778 dbSNP
rs1261639682 1788 dbSNP
rs886894713 1796 dbSNP
rs995853221 1797 dbSNP
rs1211473499 1799 dbSNP
rs537102677 1802 dbSNP
rs1273593706 1810 dbSNP
rs1234833044 1812 dbSNP
rs556886238 1816 dbSNP
rs1009931560 1817 dbSNP
rs1427598862 1818 dbSNP
rs1023327143 1823 dbSNP
rs969402135 1827 dbSNP
rs761969705 1828 dbSNP
rs567420020 1829 dbSNP
rs1167638135 1832 dbSNP
rs968701092 1833 dbSNP
rs1373061111 1838 dbSNP
rs1194480374 1839 dbSNP
rs1430772830 1842 dbSNP
rs988235672 1844 dbSNP
rs1175806178 1850 dbSNP
rs979086476 1856 dbSNP
rs1191145021 1871 dbSNP
rs1467756791 1876 dbSNP
rs536572116 1882 dbSNP
rs553283509 1888 dbSNP
rs573310239 1890 dbSNP
rs965577311 1903 dbSNP
rs1250726774 1911 dbSNP
rs958544124 1920 dbSNP
rs1334925181 1928 dbSNP
rs545412706 1936 dbSNP
rs1440260414 1938 dbSNP
rs1372081809 1939 dbSNP
rs1328147776 1941 dbSNP
rs1445083183 1948 dbSNP
rs1396270878 1950 dbSNP
rs1437001067 1953 dbSNP
rs930988676 1965 dbSNP
rs1463991939 1971 dbSNP
rs918032296 1979 dbSNP
rs949401661 1986 dbSNP
rs1171275473 1989 dbSNP
rs1453251922 1990 dbSNP
rs1402492160 1996 dbSNP
rs182078734 1999 dbSNP
rs1195075958 2008 dbSNP
rs908250755 2024 dbSNP
rs939763729 2025 dbSNP
rs147402942 2027 dbSNP
rs895631372 2028 dbSNP
rs1012784942 2040 dbSNP
rs942257962 2043 dbSNP
rs1278305769 2054 dbSNP
rs1044311856 2057 dbSNP
rs904477078 2058 dbSNP
rs1319166671 2060 dbSNP
rs544656256 2066 dbSNP
rs1329975511 2069 dbSNP
rs1037930318 2070 dbSNP
rs561341623 2071 dbSNP
rs900655888 2072 dbSNP
rs1032765952 2073 dbSNP
rs1222857008 2081 dbSNP
rs932174697 2087 dbSNP
rs1009625886 2099 dbSNP
rs1468288960 2106 dbSNP
rs766643179 2107 dbSNP
rs115697866 2116 dbSNP
rs976022196 2117 dbSNP
rs1424382187 2119 dbSNP
rs1010313149 2128 dbSNP
rs1019906706 2133 dbSNP
rs1485931166 2137 dbSNP
rs921525258 2144 dbSNP
rs751251554 2146 dbSNP
rs1166075937 2159 dbSNP
rs1280345725 2162 dbSNP
rs953083422 2163 dbSNP
rs1353918016 2167 dbSNP
rs138159554 2171 dbSNP
rs1034288899 2176 dbSNP
rs755119393 2177 dbSNP
rs1377733226 2178 dbSNP
rs1398443070 2201 dbSNP
rs939688689 2203 dbSNP
rs1158758608 2208 dbSNP
rs957248411 2209 dbSNP
rs917036835 2216 dbSNP
rs1186889826 2224 dbSNP
rs958511472 2233 dbSNP
rs948531329 2249 dbSNP
rs1044622098 2265 dbSNP
rs886054423 2266 dbSNP
rs1285266753 2269 dbSNP
rs1207150301 2271 dbSNP
rs1278492105 2272 dbSNP
rs1332887496 2275 dbSNP
rs1272958794 2278 dbSNP
rs759377240 2283 dbSNP
rs1025056968 2290 dbSNP
rs970877624 2291 dbSNP
rs886054424 2298 dbSNP
rs1428095629 2300 dbSNP
rs1325382359 2303 dbSNP
rs560402275 2307 dbSNP
rs983945235 2310 dbSNP
rs1292497492 2311 dbSNP
rs186330129 2312 dbSNP
rs1489973052 2317 dbSNP
rs963727199 2333 dbSNP
rs1419996729 2338 dbSNP
rs1264243086 2342 dbSNP
rs973606524 2343 dbSNP
rs922215954 2354 dbSNP
rs925883079 2355 dbSNP
rs886054425 2357 dbSNP
rs551091925 2358 dbSNP
rs1252604430 2365 dbSNP
rs866929136 2367 dbSNP
rs765272412 2368 dbSNP
rs190000086 2371 dbSNP
rs10406812 2395 dbSNP
rs550621569 2396 dbSNP
rs1270278975 2400 dbSNP
rs1436640605 2402 dbSNP
rs1368407769 2412 dbSNP
rs1423829754 2413 dbSNP
rs904168513 2416 dbSNP
rs1441418634 2426 dbSNP
rs886054426 2427 dbSNP
rs1167996819 2434 dbSNP
rs1409312364 2436 dbSNP
rs1264727401 2437 dbSNP
rs1420054118 2439 dbSNP
rs1170633695 2441 dbSNP
rs1452640267 2446 dbSNP
rs868241121 2449 dbSNP
rs1298421395 2451 dbSNP
rs567376758 2453 dbSNP
rs916962893 2456 dbSNP
rs1194540024 2466 dbSNP
rs536435981 2472 dbSNP
rs1055708551 2476 dbSNP
rs1379960366 2482 dbSNP
rs1317039093 2489 dbSNP
rs143923838 2498 dbSNP
rs148643181 2499 dbSNP
rs866346505 2500 dbSNP
rs951298434 2501 dbSNP
rs180698550 2502 dbSNP
rs1004944942 2503 dbSNP
rs1302013882 2504 dbSNP
rs1357724123 2507 dbSNP
rs1015446743 2509 dbSNP
rs142048723 2515 dbSNP
rs1296241573 2517 dbSNP
rs575562902 2521 dbSNP
rs1355097803 2528 dbSNP
rs1309745319 2533 dbSNP
rs1374955903 2535 dbSNP
rs973408620 2535 dbSNP
rs1174282266 2541 dbSNP
rs1203413107 2546 dbSNP
rs1406056836 2554 dbSNP
rs1261162701 2575 dbSNP
rs1443120608 2578 dbSNP
rs753422259 2579 dbSNP
rs1470704903 2582 dbSNP
rs922183351 2584 dbSNP
rs1254643111 2586 dbSNP
rs8104659 2587 dbSNP
rs1485603042 2588 dbSNP
rs1159030976 2592 dbSNP
rs1279007760 2595 dbSNP
rs1381716175 2602 dbSNP
rs1210888468 2603 dbSNP
rs891749775 2608 dbSNP
rs1271345956 2611 dbSNP
rs987688676 2613 dbSNP
rs549005141 2634 dbSNP
rs912033953 2641 dbSNP
rs1412876924 2642 dbSNP
rs1374707873 2645 dbSNP
rs112635884 2648 dbSNP
rs1157442582 2651 dbSNP
rs1402265860 2652 dbSNP
rs945379218 2665 dbSNP
rs1415737561 2668 dbSNP
rs555029183 2669 dbSNP
rs574729538 2675 dbSNP
rs925724100 2676 dbSNP
rs540421518 2679 dbSNP
rs997356702 2687 dbSNP
rs117794052 2693 dbSNP
rs1055508896 2698 dbSNP
rs1258816972 2704 dbSNP
rs894151176 2712 dbSNP
rs1014146309 2717 dbSNP
rs1337712909 2718 dbSNP
rs1258394081 2728 dbSNP
rs1237111913 2732 dbSNP
rs1317083463 2734 dbSNP
rs769121113 2743 dbSNP
rs577128024 2744 dbSNP
rs75869350 2748 dbSNP
rs1397903431 2754 dbSNP
rs1015851278 2757 dbSNP
rs140176070 2761 dbSNP
rs1431768379 2762 dbSNP
rs1261105402 2774 dbSNP
rs1163306580 2780 dbSNP
rs992459328 2781 dbSNP
rs781758597 2786 dbSNP
rs1419267611 2793 dbSNP
rs530504400 2797 dbSNP
rs185088309 2801 dbSNP
rs1427211202 2802 dbSNP
rs1259075037 2818 dbSNP
rs1185368154 2819 dbSNP
rs1465123973 2820 dbSNP
rs1015001357 2821 dbSNP
rs899283206 2825 dbSNP
rs994883467 2826 dbSNP
rs1178971689 2831 dbSNP
rs1028913997 2844 dbSNP
rs867351249 2845 dbSNP
rs987661172 2846 dbSNP
rs1294948286 2849 dbSNP
rs1019640268 2875 dbSNP
rs201602465 2876 dbSNP
rs1180628021 2880 dbSNP
rs1377910948 2891 dbSNP
rs1324106644 2898 dbSNP
rs1440675836 2900 dbSNP
rs1395704916 2914 dbSNP
rs967559675 2926 dbSNP
rs978028385 2927 dbSNP
rs1295598391 2929 dbSNP
rs925754547 2944 dbSNP
rs925723391 2947 dbSNP
rs935827008 2952 dbSNP
rs988646969 2953 dbSNP
rs550438767 2957 dbSNP
rs913114069 2966 dbSNP
rs1467712661 2971 dbSNP
rs944636065 2973 dbSNP
rs748705032 2982 dbSNP
rs1332674242 2985 dbSNP
rs991244733 2987 dbSNP
rs560956829 2988 dbSNP
rs529964980 2989 dbSNP
rs932695138 2992 dbSNP
rs1390087857 2993 dbSNP
rs1306559858 2996 dbSNP
rs886054427 2997 dbSNP
rs949722928 3004 dbSNP
rs1045637690 3005 dbSNP
rs375506694 3006 dbSNP
rs1303957914 3008 dbSNP
rs1390021965 3017 dbSNP
rs1281481901 3018 dbSNP
rs887057996 3019 dbSNP
rs777531916 3020 dbSNP
rs1299213637 3024 dbSNP
rs1432127994 3036 dbSNP
rs1371895709 3037 dbSNP
rs1171134990 3040 dbSNP
rs1006094326 3043 dbSNP
rs1037209066 3057 dbSNP
rs546821614 3058 dbSNP
rs1038570322 3067 dbSNP
rs549463504 3068 dbSNP
rs1483963684 3077 dbSNP
rs898340763 3086 dbSNP
rs373446688 3087 dbSNP
rs1346056126 3094 dbSNP
rs1195013984 3100 dbSNP
rs143949702 3109 dbSNP
rs889099818 3113 dbSNP
rs1335581227 3114 dbSNP
rs538953502 3116 dbSNP
rs1412236632 3117 dbSNP
rs1354038567 3120 dbSNP
rs552421855 3124 dbSNP
rs376844331 3129 dbSNP
rs1019187824 3130 dbSNP
rs1196594574 3135 dbSNP
rs569189077 3137 dbSNP
rs555980066 3141 dbSNP
rs763104241 3151 dbSNP
rs116311313 3155 dbSNP
rs554810387 3156 dbSNP
rs957540023 3159 dbSNP
rs1187377693 3160 dbSNP
rs975955914 3164 dbSNP
rs574594745 3165 dbSNP
rs991213754 3172 dbSNP
rs932641334 3178 dbSNP
rs10412199 3182 dbSNP
rs949690805 3184 dbSNP
rs1230616766 3187 dbSNP
rs909922703 3191 dbSNP
rs1293185068 3203 dbSNP
rs539627639 3204 dbSNP
rs371095295 3225 dbSNP
rs908203322 3226 dbSNP
rs190781294 3227 dbSNP
rs897311556 3229 dbSNP
rs1380177955 3230 dbSNP
rs1387451018 3233 dbSNP
rs146879017 3244 dbSNP
rs1046007969 3257 dbSNP
rs1415634688 3260 dbSNP
rs563181663 3263 dbSNP
rs898309490 3264 dbSNP
rs528204465 3265 dbSNP
rs1191029130 3266 dbSNP
rs1446706039 3272 dbSNP
rs1248867343 3273 dbSNP
rs745509045 3275 dbSNP
rs1467389944 3276 dbSNP
rs1229414133 3278 dbSNP
rs1359007832 3282 dbSNP
rs1305707107 3283 dbSNP
rs1001571205 3284 dbSNP
rs1304383008 3285 dbSNP
rs1285515650 3290 dbSNP
rs1224600329 3296 dbSNP
rs1226353918 3298 dbSNP
rs1320781066 3302 dbSNP
rs1265841742 3310 dbSNP
rs759241002 3311 dbSNP
rs575172884 3314 dbSNP
rs1032687986 3316 dbSNP
rs376515390 3317 dbSNP
rs932512208 3318 dbSNP
rs1415865445 3326 dbSNP
rs957321297 3332 dbSNP
rs59578136 3333 dbSNP
rs55644803 3334 dbSNP
rs1391058388 3338 dbSNP
rs1267811575 3344 dbSNP
rs1190783039 3354 dbSNP
rs1488331389 3358 dbSNP
rs1187772357 3365 dbSNP
rs889235354 3366 dbSNP
rs1008899513 3369 dbSNP
rs1222771029 3372 dbSNP
rs1429559369 3373 dbSNP
rs76339349 3377 dbSNP
rs975924890 3378 dbSNP
rs1193618100 3386 dbSNP
rs573221032 3389 dbSNP
rs1427282351 3397 dbSNP
rs1340882335 3400 dbSNP
rs529825734 3402 dbSNP
rs540478786 3405 dbSNP
rs1046825822 3406 dbSNP
rs1274096341 3408 dbSNP
rs1351592181 3411 dbSNP
rs1436912818 3411 dbSNP
rs764042495 3412 dbSNP
rs1428982416 3413 dbSNP
rs985834464 3415 dbSNP
rs546687056 3416 dbSNP
rs1365193050 3419 dbSNP
rs1400627870 3420 dbSNP
rs1192187228 3426 dbSNP
rs753229552 3432 dbSNP
rs145269449 3433 dbSNP
rs1181752417 3435 dbSNP
rs1022718119 3439 dbSNP
rs1274741219 3441 dbSNP
rs1206680175 3451 dbSNP
rs971515242 3452 dbSNP
rs1381544487 3453 dbSNP
rs981220779 3454 dbSNP
rs1037106355 3456 dbSNP
rs1277506232 3460 dbSNP
rs908172688 3464 dbSNP
rs1409146777 3477 dbSNP
rs1313407050 3479 dbSNP
rs1361309681 3482 dbSNP
rs532316280 3486 dbSNP
rs1290501826 3490 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 85300.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ggcucgugguGCGUCUGGUCg 5'
                    || ||||||| 
Target 5' -------guuCG-AGACCAGg 3'
 		1 - 13
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084041. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep1 HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3 HITS-CLIP data was present in GSM1084069. RNA binding protein: AGO2. Condition:CLIP_emetine_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084041
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep1
Location of target site ENST00000450849.2 | 3UTR | GUGGAUCACCUGAGGUCAGGAGUUCGAGACCAGGCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1084044
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep3
Location of target site ENST00000450849.2 | 3UTR | ACAGGUGGAUCACCUGAGGUCAGGAGUUCGAGACCAGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM1084069
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SigmaAb
Location of target site ENST00000450849.2 | 3UTR | GAGACAGGUGGAUCACCUGAGGUCAGGAGUUCGAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000450849.2 | 3UTR | GUUCGAGACCAGGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
203 hsa-miR-3663-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT222528 CRCP CGRP receptor component 2 2
MIRT442432 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 6
MIRT450423 BCL2L14 BCL2 like 14 2 2
MIRT456341 RCSD1 RCSD domain containing 1 2 2
MIRT479763 CCND1 cyclin D1 2 2
MIRT487162 IFRD1 interferon related developmental regulator 1 2 8
MIRT495471 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT497193 DUSP18 dual specificity phosphatase 18 2 2
MIRT499717 PAGR1 PAXIP1 associated glutamate rich protein 1 2 10
MIRT502681 CSNK1G3 casein kinase 1 gamma 3 2 8
MIRT503641 POLR2F RNA polymerase II subunit F 2 4
MIRT510824 SBNO1 strawberry notch homolog 1 2 4
MIRT512347 ZNF665 zinc finger protein 665 2 4
MIRT512528 ATCAY ATCAY, caytaxin 2 4
MIRT513246 FBXO17 F-box protein 17 2 4
MIRT513502 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 6
MIRT516033 PTAFR platelet activating factor receptor 2 2
MIRT517669 TRIM72 tripartite motif containing 72 2 2
MIRT517691 FAM175A abraxas 1, BRCA1 A complex subunit 2 2
MIRT519524 ZNF8 zinc finger protein 8 2 2
MIRT520953 SRSF10 serine and arginine rich splicing factor 10 2 2
MIRT522074 ORAI2 ORAI calcium release-activated calcium modulator 2 2 4
MIRT525333 CNGB1 cyclic nucleotide gated channel beta 1 2 2
MIRT526504 POU5F1B POU class 5 homeobox 1B 2 2
MIRT527847 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT529211 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT530071 VN1R1 vomeronasal 1 receptor 1 2 2
MIRT530639 PPIC peptidylprolyl isomerase C 2 4
MIRT530679 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT532177 SEC14L5 SEC14 like lipid binding 5 2 2
MIRT532432 DHX33 DEAH-box helicase 33 2 2
MIRT532832 ZNF704 zinc finger protein 704 2 2
MIRT534236 SLC25A16 solute carrier family 25 member 16 2 4
MIRT535115 PLXNA2 plexin A2 2 2
MIRT535563 OMD osteomodulin 2 2
MIRT536487 KIAA1468 KIAA1468 2 2
MIRT538371 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT539931 NUCB1 nucleobindin 1 2 4
MIRT562305 GINM1 glycoprotein integral membrane 1 2 2
MIRT563280 BBS10 Bardet-Biedl syndrome 10 2 2
MIRT618205 C22orf39 chromosome 22 open reading frame 39 2 2
MIRT620113 HARBI1 harbinger transposase derived 1 2 2
MIRT621189 FAM153B family with sequence similarity 153 member B 2 2
MIRT623755 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT624059 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT625016 TMIGD2 transmembrane and immunoglobulin domain containing 2 2 2
MIRT626073 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT627875 PAN2 PAN2 poly(A) specific ribonuclease subunit 2 2
MIRT629306 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT630446 IDE insulin degrading enzyme 2 2
MIRT631000 ZNF573 zinc finger protein 573 2 2
MIRT631093 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT631282 SGSM1 small G protein signaling modulator 1 2 2
MIRT631530 MYO6 myosin VI 2 2
MIRT631642 WDR91 WD repeat domain 91 2 4
MIRT631825 TMEM154 transmembrane protein 154 2 2
MIRT632778 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT633278 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT633658 SLC28A1 solute carrier family 28 member 1 2 2
MIRT634071 PLIN3 perilipin 3 2 2
MIRT634159 YME1L1 YME1 like 1 ATPase 2 2
MIRT634227 TMEM132B transmembrane protein 132B 2 2
MIRT636401 MYO5A myosin VA 2 2
MIRT638678 GCLM glutamate-cysteine ligase modifier subunit 2 2
MIRT640231 TOMM40 translocase of outer mitochondrial membrane 40 2 2
MIRT640304 PRR13 proline rich 13 2 2
MIRT641125 NPHP3 nephrocystin 3 2 2
MIRT643422 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT643700 KIAA0586 KIAA0586 2 2
MIRT644314 NFKBID NFKB inhibitor delta 2 2
MIRT644345 MPV17L MPV17 mitochondrial inner membrane protein like 2 2
MIRT645736 POLR3A RNA polymerase III subunit A 2 2
MIRT648058 TRMT10C tRNA methyltransferase 10C, mitochondrial RNase P subunit 2 2
MIRT649462 UBA5 ubiquitin like modifier activating enzyme 5 2 2
MIRT650009 KLB klotho beta 2 2
MIRT650567 YIPF4 Yip1 domain family member 4 2 2
MIRT652639 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT653887 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT655369 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT659116 DENND6A DENN domain containing 6A 2 2
MIRT659520 CHST3 carbohydrate sulfotransferase 3 2 2
MIRT659946 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT661384 RHCG Rh family C glycoprotein 2 2
MIRT662910 MED18 mediator complex subunit 18 2 2
MIRT663107 NPR1 natriuretic peptide receptor 1 2 2
MIRT663759 ZNF285 zinc finger protein 285 2 2
MIRT664554 MKI67IP nucleolar protein interacting with the FHA domain of MKI67 1 1
MIRT664611 LIMD1 LIM domains containing 1 2 2
MIRT666193 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT666794 PSMD1 proteasome 26S subunit, non-ATPase 1 2 2
MIRT668752 DDX19B DEAD-box helicase 19B 2 2
MIRT669601 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT669704 AAK1 AP2 associated kinase 1 2 2
MIRT669812 STOML1 stomatin like 1 2 2
MIRT669927 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT669951 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT670005 GPR156 G protein-coupled receptor 156 2 4
MIRT670051 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT670301 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670390 EMP2 epithelial membrane protein 2 2 2
MIRT670457 RSBN1L round spermatid basic protein 1 like 2 2
MIRT670486 DCUN1D2 defective in cullin neddylation 1 domain containing 2 2 2
MIRT670568 GLTP glycolipid transfer protein 2 2
MIRT671061 KIF1B kinesin family member 1B 2 2
MIRT671085 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT671306 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT671807 WISP3 WNT1 inducible signaling pathway protein 3 2 2
MIRT671956 SPPL3 signal peptide peptidase like 3 2 2
MIRT671993 OSTF1 osteoclast stimulating factor 1 2 2
MIRT672092 WDR5B WD repeat domain 5B 2 2
MIRT672273 SHE Src homology 2 domain containing E 2 2
MIRT672447 TTPAL alpha tocopherol transfer protein like 2 2
MIRT672451 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT673652 CYCS cytochrome c, somatic 2 2
MIRT674003 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT674054 ATXN3 ataxin 3 2 2
MIRT674248 NUP62 nucleoporin 62 2 2
MIRT674437 MIOX myo-inositol oxygenase 2 4
MIRT674476 BCL2L15 BCL2 like 15 2 2
MIRT675472 NUBPL nucleotide binding protein like 2 2
MIRT675667 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT675978 FAM126B family with sequence similarity 126 member B 2 2
MIRT676064 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT676120 SCIMP SLP adaptor and CSK interacting membrane protein 2 2
MIRT676241 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT676257 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676388 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT676744 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT676880 ENSA endosulfine alpha 2 2
MIRT676905 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT676922 KLHDC8A kelch domain containing 8A 2 2
MIRT676968 RNF19B ring finger protein 19B 2 2
MIRT677048 ZNF34 zinc finger protein 34 2 2
MIRT677114 SS18L1 SS18L1, nBAF chromatin remodeling complex subunit 2 2
MIRT677324 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT677466 PDLIM3 PDZ and LIM domain 3 2 2
MIRT677584 TRIM65 tripartite motif containing 65 2 2
MIRT677646 HAUS2 HAUS augmin like complex subunit 2 2 2
MIRT677736 MOB4 MOB family member 4, phocein 2 2
MIRT677813 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT677830 TSPYL1 TSPY like 1 2 2
MIRT678083 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678158 ZNF724P zinc finger protein 724 2 2
MIRT678256 FXN frataxin 2 2
MIRT678326 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678419 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678588 C15orf40 chromosome 15 open reading frame 40 2 2
MIRT678598 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT678831 PDE6A phosphodiesterase 6A 2 2
MIRT678945 MYADM myeloid associated differentiation marker 2 2
MIRT679046 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT679201 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT679205 FAM9B family with sequence similarity 9 member B 2 2
MIRT679223 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679270 POLM DNA polymerase mu 2 2
MIRT679288 DEGS1 delta 4-desaturase, sphingolipid 1 2 2
MIRT679316 NPHP1 nephrocystin 1 2 2
MIRT679485 CYTIP cytohesin 1 interacting protein 2 2
MIRT679551 LIPG lipase G, endothelial type 2 2
MIRT679625 TTC31 tetratricopeptide repeat domain 31 2 2
MIRT679649 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT679761 TLR6 toll like receptor 6 2 2
MIRT680124 ZNF576 zinc finger protein 576 2 2
MIRT680186 ZNF554 zinc finger protein 554 2 2
MIRT684282 CDK9 cyclin dependent kinase 9 2 2
MIRT689671 RBM23 RNA binding motif protein 23 2 2
MIRT690031 CCDC90B coiled-coil domain containing 90B 2 2
MIRT691447 CXorf36 chromosome X open reading frame 36 2 2
MIRT691547 FLYWCH2 FLYWCH family member 2 2 2
MIRT691726 LARS leucyl-tRNA synthetase 2 2
MIRT692029 ARSK arylsulfatase family member K 2 2
MIRT692635 SUSD1 sushi domain containing 1 2 2
MIRT693823 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT693864 IYD iodotyrosine deiodinase 2 2
MIRT693977 ZNF70 zinc finger protein 70 2 2
MIRT694145 CYP27C1 cytochrome P450 family 27 subfamily C member 1 2 2
MIRT695486 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT695544 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT695599 TMEM199 transmembrane protein 199 2 2
MIRT696003 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT696020 TYRO3 TYRO3 protein tyrosine kinase 2 2
MIRT696039 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT696310 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT696400 CORO7 coronin 7 2 2
MIRT696595 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2 2
MIRT698044 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT698139 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT702561 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT703018 HEATR5A HEAT repeat containing 5A 2 2
MIRT705118 C4orf29 abhydrolase domain containing 18 2 2
MIRT706303 NT5C2 5'-nucleotidase, cytosolic II 2 2
MIRT706610 CYB5B cytochrome b5 type B 2 2
MIRT706729 RFK riboflavin kinase 2 2
MIRT707321 TMEM184B transmembrane protein 184B 2 2
MIRT708652 LYRM7 LYR motif containing 7 2 2
MIRT710520 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT714283 KIF1C kinesin family member 1C 2 2
MIRT720438 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT720612 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT722756 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723296 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT724380 NEK8 NIMA related kinase 8 2 2
MIRT725105 THRA thyroid hormone receptor, alpha 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3663 Platinum-based doublet chemotherapy sensitive High Lung Adenocarcinoma tissue
hsa-mir-3663 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-3663 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-3663 Cisplatin 5460033 NSC119875 approved sensitive cell line (CIS)
hsa-mir-3663 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-mir-3663 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-3663-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-3663-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-3663-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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