miRTarBase - #MIRT512535


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pre-miRNA Information
pre-miRNA hsa-mir-4301   
Genomic Coordinates chr11: 113450023 - 113450088
Description Homo sapiens miR-4301 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4301
Sequence 11| UCCCACUACUUCACUUGUGA |30
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs184176277 2 dbSNP
rs1191324913 13 dbSNP
rs1369198005 15 dbSNP
rs1036973189 16 dbSNP
rs944900541 18 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SEMA4D   
Synonyms C9orf164, CD100, M-sema-G, SEMAJ, coll-4
Description semaphorin 4D
Transcript NM_001142287   
Other Transcripts NM_006378   
Expression
Putative miRNA Targets on SEMA4D
3'UTR of SEMA4D
(miRNA target sites are highlighted)		 
>SEMA4D|NM_001142287|3'UTR
   1 CCACCAGGAAGGAGTCCCTGACACCGACCTCAACCCCAACAAGACCCTGCTGCCACTGACCACAGCCACCCCCGGAGAAG
  81 GCCTGGTCCCCCACAACTGTGAACTGTCTTGCCCAAGCCTGCTCTGAACACAGCCATTGGGCCACCACCTGATGGGCAGA
 161 GGCGGGACAGTGGAGAAGCCTGGAACCCAAGTGGGCCTGTGACAGGAACTAAGACTTAAAAAATTAGGTGCTTACCTGGG
 241 ACAGTAAGTTCTGTCTGGCACAAGCAGGTAACCAGGATGGCTAACAGGCTTTGATAGCTGCTCGTGAACTAAAACAGCAG
 321 GGTGTGTGCAGGTTCCTCCTCTACGGTCAGGCAGCAGGCTCTGAAGGCTGATCCTACACCGTCCCAGTGACTCCCCTTGA
 401 CAGAGTGCCCCCACCCCCTAATAGCCAACAGGGTTAGCATGGCCAGCACAGATCGCTGCTTTTATTGATGCAAATCAAGC
 481 CTGCTGCTTCTCCTCCCTGCAGACTTAGCCAAGGAACTCCAAGATGCATGACTGGGACAAGAAAAGGTGAGACTCCACAT
 561 GGAAATGCCTTGCCCTAAACCTTGAATGACTGTGAGATGCGATCTGGGAGTGCATCTGTCAAGTCTTTGTGTTTTCTTCA
 641 CTAACCTCAGAATACTGGGCTCTATTTTATCAAGCGCTGCAGTTTATGCCTCTGTCCCGTCAATGCTCAGCTTCTGCAAC
 721 AGGACACCAAACTTGATGCAGAAAGCCAAATAGGTCAATTATGCAAATCTCCTGGTGCCATATTAAATTTCTTGACGATG
 801 GAATGAGTCTCATGAGTGTTTTGTTCTACCTGCTTTCAAGTCTCTAATTATTAAAGCTGTATCTCTGAAGACTGTGTCAC
 881 TGTGTGTGTGAACTTGTCCTAAAGCTACTCAGCCTTTAATCTTACACACACGTCTCTTCTTGTCTGTTGAATGACAGTTT
 961 TCATGTCTATCATAAAACCAAAGCCTCTGTTAAAAGTCAAGCCGCACCCCTCTGGTGATCCTAGCAAATACTGAGTGTCT
1041 TCCCAGCAGTGTGACAATGACCTGTTTTGCATCCCCTCTTTCTGGAGCTGGACAAATTCTCTACCAGCCTTTGTGTGGGA
1121 TCAGCATACATCGCCTGCTAATTCCTTCAGGATCCATCACAACAGGTGTCCTGAAGATGCTGGAGACACCCTGGTTGTCT
1201 CCACACGTTCCCCCTCCGCACCCCAAGTCGAGAGGCCCAGCTGCCTGTGAGGTGTGTGCTTGCCCATCCAGCCAAGGATG
1281 CCAGTCTTGCTCACGGAACCATCACATACTCATAACCTGAAGTTTTCCTGTAAAATATCCATCAGCTCACTGTGGTTCTT
1361 GCTTTGGGTGTGGCTTCAACCACTACAAACTGATGAGTGAAATGCTATGGGCTTTAGGCTTATATTCTTGGTGCTGTTTT
1441 CTGTCTCTTCTCCTGAAGTCTGGATTTCAAGCACTTTCACACTTAACAAAATAATTACATACTTGAAGTTTTCGTAATGT
1521 GGAGTGTTCTACTGGGAAATGGAGTTATGAGGATGAATTTCTGAGTCTTTCTTTGCTCTGCTGGAAAAAATAAAAATAGA
1601 GTTGTACATTGAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agUGUU-CACUUC-----AUCACCCu 5'
            ::|| |||:||     || |||| 
Target 5' tcGTAATGTGGAGTGTTCTACTGGGa 3'
 1512 - 1537 122.00 -17.20
2 
miRNA  3' aguguucacuucaUCACCCu 5'
                       |||||| 
Target 5' agcctggaacccaAGTGGGc 3'
 177 - 196 120.00 -9.00
3 
miRNA  3' aguguucaCUUCAUCACCCu 5'
                  ||| || |||| 
Target 5' taacctcaGAA-TACTGGGc 3'
 642 - 660 115.00 -5.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30108775 2 COSMIC
COSN30108770 3 COSMIC
COSN26958637 7 COSMIC
COSN30482898 7 COSMIC
COSN30160633 39 COSMIC
COSN30163101 50 COSMIC
COSN30448295 75 COSMIC
COSN31594273 92 COSMIC
COSN30526200 101 COSMIC
COSN31563026 117 COSMIC
COSN1382508 203 COSMIC
COSN23017496 206 COSMIC
COSN30177740 222 COSMIC
COSN15842552 501 COSMIC
COSN5707745 724 COSMIC
COSN14835668 797 COSMIC
COSN14768216 931 COSMIC
COSN14492587 1395 COSMIC
COSN5707744 1417 COSMIC
COSN27186727 1450 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1346010040 4 dbSNP
rs760149170 5 dbSNP
rs777861625 11 dbSNP
rs571273814 15 dbSNP
rs758794011 22 dbSNP
rs750966998 24 dbSNP
rs557467635 25 dbSNP
rs374753568 26 dbSNP
rs753389132 28 dbSNP
rs1475907562 40 dbSNP
rs375037786 42 dbSNP
rs777001255 43 dbSNP
rs1364812218 44 dbSNP
rs771083976 44 dbSNP
rs1489657682 45 dbSNP
rs1293285714 47 dbSNP
rs1435905227 48 dbSNP
rs760355976 49 dbSNP
rs1306834539 50 dbSNP
rs370395735 56 dbSNP
rs1299966766 57 dbSNP
rs565977328 60 dbSNP
rs79005557 63 dbSNP
rs1218526691 71 dbSNP
rs370391489 74 dbSNP
rs1291414020 77 dbSNP
rs1207497943 81 dbSNP
rs1247018626 82 dbSNP
rs569985822 84 dbSNP
rs1232606527 88 dbSNP
rs1258259789 90 dbSNP
rs1189899033 92 dbSNP
rs758578418 94 dbSNP
rs748439930 96 dbSNP
rs1250647685 99 dbSNP
rs1055054649 101 dbSNP
rs934891257 114 dbSNP
rs1013679000 126 dbSNP
rs959549980 128 dbSNP
rs903445105 136 dbSNP
rs1426505188 137 dbSNP
rs549927879 139 dbSNP
rs933012251 143 dbSNP
rs1458011382 145 dbSNP
rs533431297 146 dbSNP
rs993164358 148 dbSNP
rs1275309902 149 dbSNP
rs1369709535 153 dbSNP
rs1460937018 156 dbSNP
rs901557352 163 dbSNP
rs974488954 164 dbSNP
rs943129554 165 dbSNP
rs1210150328 167 dbSNP
rs909006236 173 dbSNP
rs985036286 195 dbSNP
rs1464433762 205 dbSNP
rs950626655 206 dbSNP
rs1192074192 209 dbSNP
rs117120897 210 dbSNP
rs1180449876 216 dbSNP
rs146625999 218 dbSNP
rs1245442123 227 dbSNP
rs1196171503 233 dbSNP
rs1411631673 235 dbSNP
rs1473143100 244 dbSNP
rs1161561653 246 dbSNP
rs943162484 248 dbSNP
rs981387075 254 dbSNP
rs1404823990 261 dbSNP
rs971401756 264 dbSNP
rs1324355837 267 dbSNP
rs910402250 272 dbSNP
rs1023403814 275 dbSNP
rs1407973591 282 dbSNP
rs774792641 285 dbSNP
rs1287672695 287 dbSNP
rs1350838174 289 dbSNP
rs547958248 291 dbSNP
rs1291044429 296 dbSNP
rs45559838 297 dbSNP
rs1012981246 302 dbSNP
rs1209881745 303 dbSNP
rs893215444 304 dbSNP
rs925306429 312 dbSNP
rs1251739336 315 dbSNP
rs1483552274 317 dbSNP
rs142962871 318 dbSNP
rs1184854749 320 dbSNP
rs111907314 322 dbSNP
rs535576136 326 dbSNP
rs1315905699 327 dbSNP
rs1272027304 328 dbSNP
rs1472612769 342 dbSNP
rs755393259 344 dbSNP
rs917976806 345 dbSNP
rs992226486 349 dbSNP
rs148594433 379 dbSNP
rs1371154708 380 dbSNP
rs144673712 381 dbSNP
rs1440309840 386 dbSNP
rs1339487663 396 dbSNP
rs1245010501 402 dbSNP
rs1006469512 403 dbSNP
rs1285629669 403 dbSNP
rs952355258 407 dbSNP
rs1026572635 411 dbSNP
rs1274532237 417 dbSNP
rs543038999 419 dbSNP
rs1254566648 420 dbSNP
rs901529732 420 dbSNP
rs993136762 420 dbSNP
rs901485422 421 dbSNP
rs577598352 422 dbSNP
rs1039111931 429 dbSNP
rs751855466 434 dbSNP
rs1333700936 443 dbSNP
rs1188458594 444 dbSNP
rs943099470 449 dbSNP
rs756583947 454 dbSNP
rs1048882320 455 dbSNP
rs1431606019 461 dbSNP
rs73502347 466 dbSNP
rs1177280780 468 dbSNP
rs1396400040 469 dbSNP
rs751065746 470 dbSNP
rs1054736608 475 dbSNP
rs149362980 479 dbSNP
rs763702811 486 dbSNP
rs1433701981 502 dbSNP
rs919160482 503 dbSNP
rs1297739535 507 dbSNP
rs981298163 514 dbSNP
rs1230197903 520 dbSNP
rs1254795790 521 dbSNP
rs1344669654 526 dbSNP
rs971308209 535 dbSNP
rs1201402049 536 dbSNP
rs572263681 548 dbSNP
rs903065716 549 dbSNP
rs1463745664 559 dbSNP
rs1041635082 560 dbSNP
rs762351430 584 dbSNP
rs555543062 587 dbSNP
rs536118083 592 dbSNP
rs1196579983 594 dbSNP
rs1377016252 595 dbSNP
rs991907036 601 dbSNP
rs1456420655 603 dbSNP
rs1320831454 606 dbSNP
rs1366691088 611 dbSNP
rs1179897057 612 dbSNP
rs1384572460 617 dbSNP
rs1299744709 623 dbSNP
rs1331092277 633 dbSNP
rs1234386408 634 dbSNP
rs1265443931 636 dbSNP
rs1479461396 639 dbSNP
rs1208302901 640 dbSNP
rs1231904868 645 dbSNP
rs570267308 649 dbSNP
rs1486858655 656 dbSNP
rs1208200255 667 dbSNP
rs1266578562 669 dbSNP
rs1433737448 671 dbSNP
rs550484789 675 dbSNP
rs999006275 676 dbSNP
rs1409422932 688 dbSNP
rs1472159953 694 dbSNP
rs570882029 696 dbSNP
rs551460209 698 dbSNP
rs1029854346 699 dbSNP
rs866864785 704 dbSNP
rs1354249320 711 dbSNP
rs998397827 716 dbSNP
rs900091134 717 dbSNP
rs531269129 722 dbSNP
rs1292478247 723 dbSNP
rs1038687346 732 dbSNP
rs1387808018 735 dbSNP
rs1285789794 739 dbSNP
rs1372916392 747 dbSNP
rs539427645 751 dbSNP
rs1289207658 752 dbSNP
rs1319028388 753 dbSNP
rs1242655803 754 dbSNP
rs572745286 763 dbSNP
rs1488859028 766 dbSNP
rs1450694343 777 dbSNP
rs562745130 778 dbSNP
rs1224573055 782 dbSNP
rs768794175 786 dbSNP
rs1357773966 789 dbSNP
rs570899822 793 dbSNP
rs547870829 796 dbSNP
rs4876978 797 dbSNP
rs1182704267 799 dbSNP
rs1420842494 799 dbSNP
rs1413703567 805 dbSNP
rs1421740016 807 dbSNP
rs1382639922 812 dbSNP
rs1159955596 813 dbSNP
rs1026546445 816 dbSNP
rs929074016 821 dbSNP
rs559562312 823 dbSNP
rs1416745642 835 dbSNP
rs1305434850 836 dbSNP
rs1369312740 846 dbSNP
rs1409598468 847 dbSNP
rs1309057684 851 dbSNP
rs1375769279 854 dbSNP
rs762913137 854 dbSNP
rs1312313322 861 dbSNP
rs1463872422 861 dbSNP
rs1322334467 864 dbSNP
rs1406839723 865 dbSNP
rs1182059238 869 dbSNP
rs548922966 873 dbSNP
rs750583076 878 dbSNP
rs1234349275 882 dbSNP
rs1482171545 887 dbSNP
rs529122820 889 dbSNP
rs1166249333 891 dbSNP
rs775638061 891 dbSNP
rs1388825738 892 dbSNP
rs919070616 894 dbSNP
rs1429722424 910 dbSNP
rs1045546247 913 dbSNP
rs972334259 918 dbSNP
rs563415505 919 dbSNP
rs1302422370 920 dbSNP
rs1380241785 925 dbSNP
rs1255144659 926 dbSNP
rs1295547102 929 dbSNP
rs4877075 931 dbSNP
rs1007308627 932 dbSNP
rs34831641 932 dbSNP
rs398046606 932 dbSNP
rs1310160900 933 dbSNP
rs776512207 935 dbSNP
rs1256225843 937 dbSNP
rs991503661 937 dbSNP
rs568886168 938 dbSNP
rs1288030554 939 dbSNP
rs957625658 940 dbSNP
rs1316390174 942 dbSNP
rs368738848 942 dbSNP
rs926047424 947 dbSNP
rs977479594 949 dbSNP
rs1032771165 952 dbSNP
rs1187542486 953 dbSNP
rs1422288297 957 dbSNP
rs1413108096 958 dbSNP
rs183449618 961 dbSNP
rs577554029 964 dbSNP
rs1377164090 965 dbSNP
rs1471051274 975 dbSNP
rs1318823929 983 dbSNP
rs903048606 989 dbSNP
rs1435925698 992 dbSNP
rs1293075402 998 dbSNP
rs1041603833 1002 dbSNP
rs7389229 1003 dbSNP
rs1363038195 1005 dbSNP
rs964322773 1010 dbSNP
rs1296849534 1013 dbSNP
rs1325449849 1028 dbSNP
rs1451053036 1029 dbSNP
rs1464907730 1036 dbSNP
rs896486420 1036 dbSNP
rs1217383205 1038 dbSNP
rs140764677 1046 dbSNP
rs1165122663 1048 dbSNP
rs1477348806 1053 dbSNP
rs1190953735 1060 dbSNP
rs938031450 1062 dbSNP
rs571829260 1067 dbSNP
rs1157143054 1069 dbSNP
rs1388255971 1077 dbSNP
rs1406755015 1080 dbSNP
rs1415151638 1085 dbSNP
rs984913123 1087 dbSNP
rs1007212020 1099 dbSNP
rs1478010554 1103 dbSNP
rs1226356925 1105 dbSNP
rs1265309112 1120 dbSNP
rs1184695691 1127 dbSNP
rs1329508836 1129 dbSNP
rs193068210 1130 dbSNP
rs1027297183 1132 dbSNP
rs147274842 1133 dbSNP
rs1332990473 1134 dbSNP
rs1221393115 1137 dbSNP
rs1272736412 1138 dbSNP
rs1270254583 1140 dbSNP
rs1490939630 1154 dbSNP
rs576603765 1157 dbSNP
rs112080880 1159 dbSNP
rs1411472987 1160 dbSNP
rs1470665667 1173 dbSNP
rs578088072 1184 dbSNP
rs1183505407 1189 dbSNP
rs868804632 1201 dbSNP
rs1276925046 1205 dbSNP
rs551309512 1205 dbSNP
rs540134814 1206 dbSNP
rs1368850678 1207 dbSNP
rs1407760570 1208 dbSNP
rs1056147162 1216 dbSNP
rs935951423 1217 dbSNP
rs1293630691 1218 dbSNP
rs1335960177 1219 dbSNP
rs1443861980 1220 dbSNP
rs528853630 1229 dbSNP
rs570814478 1229 dbSNP
rs1458959388 1230 dbSNP
rs772243123 1234 dbSNP
rs986167258 1247 dbSNP
rs748162778 1254 dbSNP
rs1391887397 1258 dbSNP
rs1163737366 1272 dbSNP
rs977427448 1273 dbSNP
rs1184164000 1275 dbSNP
rs1235955190 1277 dbSNP
rs775199211 1287 dbSNP
rs557823842 1289 dbSNP
rs1425504878 1290 dbSNP
rs80149586 1293 dbSNP
rs1427860620 1295 dbSNP
rs976897790 1299 dbSNP
rs1267909799 1301 dbSNP
rs534253576 1306 dbSNP
rs568552532 1307 dbSNP
rs1193019969 1309 dbSNP
rs1167907164 1312 dbSNP
rs1033156686 1316 dbSNP
rs964588392 1316 dbSNP
rs188433997 1317 dbSNP
rs1411463124 1337 dbSNP
rs768795579 1357 dbSNP
rs1331778515 1359 dbSNP
rs1339575791 1367 dbSNP
rs1252661547 1369 dbSNP
rs1199492708 1370 dbSNP
rs1362436004 1376 dbSNP
rs1226791392 1377 dbSNP
rs999976540 1394 dbSNP
rs575645327 1395 dbSNP
rs967175878 1397 dbSNP
rs984757278 1399 dbSNP
rs1014043676 1407 dbSNP
rs952995598 1408 dbSNP
rs1447766589 1412 dbSNP
rs555954191 1416 dbSNP
rs111299804 1425 dbSNP
rs1476269335 1442 dbSNP
rs1313330541 1445 dbSNP
rs1304013085 1447 dbSNP
rs1170638102 1450 dbSNP
rs1442530852 1455 dbSNP
rs1368138741 1459 dbSNP
rs1324886958 1464 dbSNP
rs1469955351 1471 dbSNP
rs569869952 1472 dbSNP
rs546570626 1477 dbSNP
rs1338334276 1480 dbSNP
rs780344151 1485 dbSNP
rs1433725470 1486 dbSNP
rs28380655 1486 dbSNP
rs1295474788 1488 dbSNP
rs1447069827 1490 dbSNP
rs1230029352 1491 dbSNP
rs1273491527 1494 dbSNP
rs1323300125 1497 dbSNP
rs1204503035 1501 dbSNP
rs183153974 1503 dbSNP
rs1463590141 1505 dbSNP
rs1208263541 1507 dbSNP
rs1262306499 1508 dbSNP
rs1430291733 1510 dbSNP
rs1376820068 1513 dbSNP
rs573526138 1513 dbSNP
rs1480645472 1514 dbSNP
rs756406588 1516 dbSNP
rs897577182 1518 dbSNP
rs1409378495 1519 dbSNP
rs1055726837 1531 dbSNP
rs1296260611 1533 dbSNP
rs1461257620 1534 dbSNP
rs1002588845 1548 dbSNP
rs905218840 1551 dbSNP
rs1345197467 1553 dbSNP
rs138133454 1555 dbSNP
rs1394551896 1565 dbSNP
rs1014076698 1567 dbSNP
rs894271911 1568 dbSNP
rs1055633602 1569 dbSNP
rs1327395227 1569 dbSNP
rs770654889 1571 dbSNP
rs1486909506 1573 dbSNP
rs575910171 1575 dbSNP
rs1266610570 1578 dbSNP
rs1490447372 1597 dbSNP
rs1201395423 1599 dbSNP
rs1249119163 1601 dbSNP
rs1459278635 1608 dbSNP
rs1036494207 1610 dbSNP
rs1364987530 1614 dbSNP
rs1455938179 1615 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 10507.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aguguucacuuCAUCACCCu 5'
                     |||||||| 
Target 5' ------uuucuGUAGUGGGg 3'
 		1 - 14
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000450295.1 | 3UTR | UUUCUGUAGUGGGGGAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
83 hsa-miR-4301 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081134 LDLR low density lipoprotein receptor 2 4
MIRT090911 ARHGEF26 Rho guanine nucleotide exchange factor 26 2 2
MIRT229436 MECP2 methyl-CpG binding protein 2 2 2
MIRT274717 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT350957 BACH1 BTB domain and CNC homolog 1 2 2
MIRT386722 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT446022 PEX3 peroxisomal biogenesis factor 3 2 2
MIRT481303 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 14
MIRT483959 ZNF354B zinc finger protein 354B 2 6
MIRT495667 TUBAL3 tubulin alpha like 3 2 2
MIRT496554 TBX15 T-box 15 2 2
MIRT497702 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT498105 RMND5A required for meiotic nuclear division 5 homolog A 2 2
MIRT512535 SEMA4D semaphorin 4D 2 2
MIRT512556 MFN2 mitofusin 2 2 6
MIRT521465 RABGAP1 RAB GTPase activating protein 1 2 6
MIRT526236 C2orf15 chromosome 2 open reading frame 15 2 2
MIRT526743 HLA-DOB major histocompatibility complex, class II, DO beta 2 2
MIRT527578 BRD7 bromodomain containing 7 2 4
MIRT528038 WT1 Wilms tumor 1 2 2
MIRT528267 GPRIN2 G protein regulated inducer of neurite outgrowth 2 2 2
MIRT528505 HTR7 5-hydroxytryptamine receptor 7 2 4
MIRT528758 RPS27 ribosomal protein S27 2 6
MIRT528999 IPO9 importin 9 2 2
MIRT529701 MRPL30 mitochondrial ribosomal protein L30 2 2
MIRT529781 C17orf82 chromosome 17 open reading frame 82 2 2
MIRT533797 TMEM119 transmembrane protein 119 2 6
MIRT535308 PHF12 PHD finger protein 12 2 2
MIRT535917 MKL2 MKL1/myocardin like 2 2 2
MIRT544892 OSBPL1A oxysterol binding protein like 1A 2 2
MIRT555423 PPIC peptidylprolyl isomerase C 2 2
MIRT562068 KLHL15 kelch like family member 15 2 2
MIRT565623 SLC31A1 solute carrier family 31 member 1 2 2
MIRT565661 SIX1 SIX homeobox 1 2 2
MIRT570138 IL1RL2 interleukin 1 receptor like 2 2 2
MIRT571045 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT621232 LMAN1 lectin, mannose binding 1 2 2
MIRT622272 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT623844 GAN gigaxonin 2 2
MIRT626158 NFYA nuclear transcription factor Y subunit alpha 2 2
MIRT626464 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT632087 ALDH1A2 aldehyde dehydrogenase 1 family member A2 2 2
MIRT637243 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT642710 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT643611 KANSL3 KAT8 regulatory NSL complex subunit 3 2 2
MIRT644270 PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 2 2
MIRT645470 SPIN3 spindlin family member 3 2 2
MIRT649193 DNPEP aspartyl aminopeptidase 2 2
MIRT650776 POP4 POP4 homolog, ribonuclease P/MRP subunit 2 2
MIRT651345 ZC2HC1C zinc finger C2HC-type containing 1C 2 2
MIRT652237 TRAPPC3L trafficking protein particle complex 3 like 2 2
MIRT652587 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT654591 PURA purine rich element binding protein A 2 2
MIRT654649 PTAFR platelet activating factor receptor 2 2
MIRT656842 KLF7 Kruppel like factor 7 2 2
MIRT657209 IKZF2 IKAROS family zinc finger 2 2 2
MIRT658513 ETV3 ETS variant 3 2 2
MIRT659448 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT668816 CYLD CYLD lysine 63 deubiquitinase 2 2
MIRT669067 CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 2 2
MIRT677711 ELOF1 elongation factor 1 homolog 2 4
MIRT687146 PTPN12 protein tyrosine phosphatase, non-receptor type 12 2 2
MIRT698498 THOC2 THO complex 2 2 2
MIRT707930 PPP1R3D protein phosphatase 1 regulatory subunit 3D 4 2
MIRT708737 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT710031 POLL DNA polymerase lambda 2 2
MIRT712175 STK4 serine/threonine kinase 4 2 2
MIRT715297 MAPK1 mitogen-activated protein kinase 1 2 2
MIRT716892 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 2
MIRT717378 RBM41 RNA binding motif protein 41 2 2
MIRT718082 CLIC5 chloride intracellular channel 5 2 2
MIRT718721 ANKRD18A ankyrin repeat domain 18A 2 2
MIRT719152 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT719224 CAMK4 calcium/calmodulin dependent protein kinase IV 2 2
MIRT719528 SRCIN1 SRC kinase signaling inhibitor 1 2 2
MIRT719861 KLF2 Kruppel like factor 2 2 2
MIRT720326 CAMK2G calcium/calmodulin dependent protein kinase II gamma 2 2
MIRT721596 SREBF1 sterol regulatory element binding transcription factor 1 2 2
MIRT722020 NEBL nebulette 2 2
MIRT722484 QSOX1 quiescin sulfhydryl oxidase 1 2 2
MIRT722614 TEAD1 TEA domain transcription factor 1 2 2
MIRT723664 RPTN repetin 2 2
MIRT723939 SVOP SV2 related protein 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4301 Cisplatin 5460033 NSC119875 approved sensitive High Hepatocellular Carcinoma cell line (Hep3B, 97L)
hsa-miR-4301 Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-mir-4301 Paclitaxel 36314 NSC125973 approved resistant cell line (BAS)
hsa-mir-4301 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-4301 Doxorubicin 31703 NSC123127 approved sensitive cell line (W1)
hsa-mir-4301 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-4301 Topotecan 60699 NSC609699 approved sensitive cell line (W1)
hsa-miR-4301 Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4301 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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