miRTarBase - #MIRT512691


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pre-miRNA Information
pre-miRNA hsa-mir-4457   
Genomic Coordinates chr5: 1309310 - 1309377
Description Homo sapiens miR-4457 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4457
Sequence 43| UCACAAGGUAUUGACUGGCGUA |64
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1031676297 8 dbSNP
rs1249861366 14 dbSNP
rs115769169 17 dbSNP
rs968846507 19 dbSNP
rs540870271 20 dbSNP
rs993130937 22 dbSNP
Putative Targets

Gene Information
Gene Symbol POP1   
Synonyms ANXD2
Description POP1 homolog, ribonuclease P/MRP subunit
Transcript NM_001145860   
Other Transcripts NM_001145861 , NM_015029   
Expression
Putative miRNA Targets on POP1
3'UTR of POP1
(miRNA target sites are highlighted)		 
>POP1|NM_001145860|3'UTR
   1 ATGCGTGCTTGTATCCCAGCAGGGCATAGATAATACGTTATTATTGTCTGCCAAGTTCTACATGTGGAGAATCTGCTTCT
  81 GCTTTAAAATATCATGTGAAACTCCCTGGAAACAAGAATAAAAAATTATGTATTATGCAGATGATGAAATGTTTACATCA
 161 TTCCAGTAATGTCATTGATTTTCATCTTTCCCTGTCCTTGCTGTAATACTTTTAAATTATTTGGCCAAAAGCTTTGTATT
 241 ATGATCTCTTGGTCTGTGTAGTTGTGGCTGAAAATAATGAGAAGCTCTACGAGTTATCATCCCCTTTTTTTGTTAGAAAC
 321 AAAGGGCTTGTCAGGTCTATTTGAAAAACCTCATAGTCATGTGATAAGCAACAATAGATGTTTAATGATTTCACTGTTAT
 401 AGCAGAAGACAAGAGAAGACGCTTGGCCTCTGTACATGAAATATGGGCTCCTGATGGACCTCATTCAATTCTGTACTGTG
 481 ATTTCCATGCCGAACAACTCAAGCCTTAAAGAGAGAAATCATGGACAACTGATTTCTGCCTGTTTTCAGGCAGGCACAGT
 561 TTATGGCGTCAGTGCTAGGCTGGAATTAGAAAGTGGGGGTCTATGACGTGGACTTCCTGACTCTTTGATCTCTTTGTTGT
 641 TGACCAACACTTGATCCTACTAGTTACTTAATTTTTTTAAGTAAAAAATTATTATTATTTTGTTTCTGCAAAGATTTTCT
 721 CAAAGCCATAGAGGAGCATTTCTCAGAATATGTTCTATGATATGTGTCACCTAAAAAAGTAAGAGATTCCAAGGTCAGGT
 801 TGATATGGAAACTCTAGGTTAAATAAAGTTAAGCATTTCTTTATGAAAGAACTTCTGGAAACTTCCATGTGATAATGTGC
 881 ATTGCGGATCTCTAGGAAGGAAATGATAGTGTATAGTATTTTCTAAATACTTGTGATTCCTAAAGTTCTCTTACAAGGAG
 961 CCCTTTGTAGGACCAGTGTTCTTAGTAGCGCGCTTTGGGCAGTGTGGCTGTGTAGTGCATAGCTACCTCTGCAAGGTGAT
1041 AACTAAGCCGGCAAGCTGCCTTTCAACACTCATGCAGTCACGTTGTCCACCTGAGATTCTCAACAGGGTATAAAAGGAAG
1121 GTCTCATCTTGCCTCACAGGAAGAGTGGGCTCAGTGTGGCTTTTTTCCAACTATGGAGAAACTCAGTGCTCATCTACTTT
1201 AAGTTTCCACATATGGCTTGCTCATAGCCTTGGTCCTTACCTTTCCTGCCATAACTTTCTAGAAGAGCTTAATGGGATTT
1281 TTTTTCTAAAAAATGTAAATATGCAGTTAGGCATTATTTTATGTAAATGCATTGGGTTTTTACTGTAGCATTTGGCACTA
1361 AATGGCTTTGGGGGTGATGAGGTGGGGAAGGATACAGCAGGTGGTACAGTAGTCAGGAAGTACCTGCCACCAATGAGATG
1441 TCTGATGCTTTGCCTCTTACCATGCCTCTGAATGTCTTTGGATCCAACCCAGATGAGACTGAAAAAAAAAAAACAGTGTA
1521 ACTAAGTGGCATCTGTAAACAGAATAAATGAAAATGTCACCTGATGTTCAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' augCGGUCAGUUAUGGAACAcu 5'
             ||||   || :|:||||  
Target 5' ttgGCCA---AAAGCTTTGTat 3'
 221 - 239 120.00 -7.70
2 
miRNA  3' augcggucaguuaugGAACACu 5'
                         |||||| 
Target 5' agtattttctaaataCTTGTGa 3'
 915 - 936 120.00 -8.80
3 
miRNA  3' augcGGUCAGUUAUGGAACACu 5'
              |::|  | | || |||| 
Target 5' acttCTGGAAACTTCCATGTGa 3'
 851 - 872 118.00 -9.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26989922 5 COSMIC
COSN31577256 26 COSMIC
COSN28876211 37 COSMIC
COSN31612682 38 COSMIC
COSN31510490 61 COSMIC
COSN30182629 65 COSMIC
COSN16725326 93 COSMIC
COSN18719874 131 COSMIC
COSN26656904 220 COSMIC
COSN25707551 598 COSMIC
COSN22346252 1127 COSMIC
COSN22528125 1195 COSMIC
COSN21187463 1224 COSMIC
COSN32064593 1240 COSMIC
COSN20594945 1331 COSMIC
COSN9690308 1356 COSMIC
COSN20105736 1514 COSMIC
COSN27211949 1514 COSMIC
COSN27582978 1515 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1459840475 2 dbSNP
rs771532722 5 dbSNP
rs181502091 6 dbSNP
rs762325738 7 dbSNP
rs770210986 8 dbSNP
rs1260438635 9 dbSNP
rs773625783 11 dbSNP
rs376071548 14 dbSNP
rs766674051 15 dbSNP
rs1469717133 16 dbSNP
rs1177672105 18 dbSNP
rs987113472 19 dbSNP
rs374995416 25 dbSNP
rs201959918 27 dbSNP
rs1166984061 34 dbSNP
rs1405950246 36 dbSNP
rs767646138 37 dbSNP
rs752722442 38 dbSNP
rs369313380 46 dbSNP
rs1281422503 52 dbSNP
rs1238443379 72 dbSNP
rs907521548 77 dbSNP
rs1177671801 78 dbSNP
rs1058251 80 dbSNP
rs1479443587 85 dbSNP
rs1283254840 93 dbSNP
rs186955025 95 dbSNP
rs973554931 96 dbSNP
rs1322862784 114 dbSNP
rs1197162790 116 dbSNP
rs945695167 120 dbSNP
rs920479444 122 dbSNP
rs1356339857 124 dbSNP
rs143698283 132 dbSNP
rs776327495 133 dbSNP
rs1211515310 142 dbSNP
rs750899046 147 dbSNP
rs1437213953 155 dbSNP
rs757865201 159 dbSNP
rs7816896 164 dbSNP
rs751174070 177 dbSNP
rs1301177564 194 dbSNP
rs1474280489 204 dbSNP
rs1186882229 213 dbSNP
rs939371402 216 dbSNP
rs1157817611 229 dbSNP
rs1034601503 231 dbSNP
rs1052408706 240 dbSNP
rs1426757303 243 dbSNP
rs1191320565 247 dbSNP
rs1487856724 248 dbSNP
rs1266104641 254 dbSNP
rs1220933635 261 dbSNP
rs894280758 270 dbSNP
rs539650704 272 dbSNP
rs1011023213 290 dbSNP
rs1476540653 291 dbSNP
rs1044193879 292 dbSNP
rs1324923238 293 dbSNP
rs899999482 296 dbSNP
rs1303648475 301 dbSNP
rs34631696 301 dbSNP
rs1219925510 302 dbSNP
rs374374186 303 dbSNP
rs878909554 304 dbSNP
rs1301314459 305 dbSNP
rs1027719041 310 dbSNP
rs1361089937 318 dbSNP
rs754613928 325 dbSNP
rs1451333650 330 dbSNP
rs952049489 335 dbSNP
rs1176378669 336 dbSNP
rs1435652233 340 dbSNP
rs1432188321 342 dbSNP
rs983844022 350 dbSNP
rs1195129624 354 dbSNP
rs1479126662 359 dbSNP
rs1315368777 361 dbSNP
rs1015211040 375 dbSNP
rs1029940587 376 dbSNP
rs10104260 377 dbSNP
rs1323023196 380 dbSNP
rs192191665 385 dbSNP
rs922105417 388 dbSNP
rs535584385 394 dbSNP
rs1341113118 401 dbSNP
rs1294737055 404 dbSNP
rs932127478 406 dbSNP
rs1014633684 409 dbSNP
rs1303156532 420 dbSNP
rs3735882 421 dbSNP
rs755867618 422 dbSNP
rs973179585 423 dbSNP
rs1465669063 425 dbSNP
rs574927952 428 dbSNP
rs906827515 437 dbSNP
rs1427204966 444 dbSNP
rs969261702 445 dbSNP
rs543769567 454 dbSNP
rs938607281 467 dbSNP
rs1282424197 469 dbSNP
rs1055689166 474 dbSNP
rs374468467 475 dbSNP
rs1484673318 478 dbSNP
rs1461087615 480 dbSNP
rs557651380 492 dbSNP
rs575019196 493 dbSNP
rs1250784686 496 dbSNP
rs1225170556 503 dbSNP
rs887855155 503 dbSNP
rs939299408 521 dbSNP
rs1313245844 528 dbSNP
rs10104499 529 dbSNP
rs1380185751 559 dbSNP
rs1332916559 560 dbSNP
rs913940497 568 dbSNP
rs759791368 570 dbSNP
rs1454996018 580 dbSNP
rs1175873251 586 dbSNP
rs1165591987 599 dbSNP
rs1015346931 605 dbSNP
rs1393638062 608 dbSNP
rs966042113 623 dbSNP
rs1241645075 651 dbSNP
rs976759737 655 dbSNP
rs1458341384 660 dbSNP
rs1249918556 668 dbSNP
rs1194148192 672 dbSNP
rs1029182162 688 dbSNP
rs1466032785 699 dbSNP
rs953573423 714 dbSNP
rs946667850 717 dbSNP
rs1311115328 729 dbSNP
rs1240435349 730 dbSNP
rs1043823897 746 dbSNP
rs899893016 753 dbSNP
rs1159651217 764 dbSNP
rs1326352708 773 dbSNP
rs34911538 773 dbSNP
rs748752781 777 dbSNP
rs1304315989 782 dbSNP
rs772050521 784 dbSNP
rs7821171 797 dbSNP
rs562269566 806 dbSNP
rs1004507102 818 dbSNP
rs1363425813 818 dbSNP
rs1441145357 822 dbSNP
rs1016222694 825 dbSNP
rs897498380 827 dbSNP
rs879068116 829 dbSNP
rs994881547 834 dbSNP
rs1232523901 838 dbSNP
rs1261167782 852 dbSNP
rs1352949290 853 dbSNP
rs1221684734 872 dbSNP
rs184030369 874 dbSNP
rs1489822199 877 dbSNP
rs144169076 879 dbSNP
rs1240593240 883 dbSNP
rs928304515 886 dbSNP
rs75232257 887 dbSNP
rs1056142472 899 dbSNP
rs1282028661 902 dbSNP
rs1195721280 905 dbSNP
rs185942526 907 dbSNP
rs1034847892 908 dbSNP
rs1183182966 911 dbSNP
rs10955150 925 dbSNP
rs1384573032 940 dbSNP
rs1157079105 941 dbSNP
rs886902307 943 dbSNP
rs768976702 963 dbSNP
rs10955151 968 dbSNP
rs901864339 969 dbSNP
rs913772738 977 dbSNP
rs10955152 987 dbSNP
rs1029231564 990 dbSNP
rs868542789 991 dbSNP
rs1011743740 992 dbSNP
rs921264744 999 dbSNP
rs932759530 1008 dbSNP
rs1051178451 1010 dbSNP
rs1221140948 1011 dbSNP
rs546975809 1013 dbSNP
rs891302657 1014 dbSNP
rs1280613907 1015 dbSNP
rs940137446 1017 dbSNP
rs1326231153 1019 dbSNP
rs189929100 1023 dbSNP
rs1365229446 1024 dbSNP
rs928388556 1027 dbSNP
rs1175861478 1028 dbSNP
rs960004162 1045 dbSNP
rs535657371 1048 dbSNP
rs1337417163 1049 dbSNP
rs991145044 1050 dbSNP
rs1037299814 1051 dbSNP
rs898718930 1052 dbSNP
rs1335546897 1055 dbSNP
rs915871232 1067 dbSNP
rs931221908 1069 dbSNP
rs1242120166 1072 dbSNP
rs1201274608 1073 dbSNP
rs995753917 1078 dbSNP
rs1048312141 1080 dbSNP
rs182503719 1082 dbSNP
rs1339222654 1083 dbSNP
rs1196708718 1104 dbSNP
rs1253066263 1112 dbSNP
rs1450612918 1113 dbSNP
rs531288364 1121 dbSNP
rs1383858902 1132 dbSNP
rs1336361308 1136 dbSNP
rs1253533309 1139 dbSNP
rs904859530 1141 dbSNP
rs1402568275 1146 dbSNP
rs1171149254 1155 dbSNP
rs1409375106 1169 dbSNP
rs10955153 1171 dbSNP
rs1034690195 1174 dbSNP
rs148659164 1176 dbSNP
rs1475209862 1184 dbSNP
rs1166660250 1192 dbSNP
rs1458773362 1195 dbSNP
rs557289641 1201 dbSNP
rs577554010 1217 dbSNP
rs968399655 1226 dbSNP
rs1271472051 1228 dbSNP
rs1050387219 1230 dbSNP
rs935148000 1240 dbSNP
rs1360651270 1242 dbSNP
rs200799750 1245 dbSNP
rs889080204 1246 dbSNP
rs1244064753 1247 dbSNP
rs1011799234 1252 dbSNP
rs979367685 1253 dbSNP
rs1021810388 1255 dbSNP
rs1352729914 1257 dbSNP
rs1325482114 1261 dbSNP
rs1407996917 1266 dbSNP
rs1425168591 1267 dbSNP
rs921305390 1268 dbSNP
rs112219911 1271 dbSNP
rs563667149 1278 dbSNP
rs1235162435 1281 dbSNP
rs932600483 1286 dbSNP
rs986891642 1302 dbSNP
rs912623639 1303 dbSNP
rs1176169756 1312 dbSNP
rs1247901316 1317 dbSNP
rs1468126218 1317 dbSNP
rs1310888525 1321 dbSNP
rs1225389366 1322 dbSNP
rs1490637825 1329 dbSNP
rs940189483 1331 dbSNP
rs534141026 1334 dbSNP
rs1037628822 1337 dbSNP
rs1220703999 1346 dbSNP
rs1319006954 1347 dbSNP
rs999022216 1350 dbSNP
rs1228401360 1352 dbSNP
rs1223392989 1355 dbSNP
rs920093271 1363 dbSNP
rs1276630932 1370 dbSNP
rs545274172 1371 dbSNP
rs1044647058 1372 dbSNP
rs778609398 1375 dbSNP
rs1301122181 1380 dbSNP
rs904867754 1382 dbSNP
rs187202784 1388 dbSNP
rs1345456606 1390 dbSNP
rs1157952066 1393 dbSNP
rs77187656 1397 dbSNP
rs542818706 1399 dbSNP
rs763447395 1407 dbSNP
rs1199509054 1408 dbSNP
rs1183054229 1409 dbSNP
rs1410945222 1410 dbSNP
rs1268772856 1421 dbSNP
rs1422926662 1423 dbSNP
rs1009307210 1427 dbSNP
rs1170708821 1434 dbSNP
rs765869500 1436 dbSNP
rs1427522180 1439 dbSNP
rs191916989 1445 dbSNP
rs908442931 1457 dbSNP
rs76120586 1459 dbSNP
rs183661300 1461 dbSNP
rs1416513238 1466 dbSNP
rs1301220609 1469 dbSNP
rs976608563 1482 dbSNP
rs1401720852 1485 dbSNP
rs1362421261 1487 dbSNP
rs1288004007 1489 dbSNP
rs1378514943 1490 dbSNP
rs1215445739 1491 dbSNP
rs922386776 1493 dbSNP
rs1340497636 1494 dbSNP
rs1228059625 1496 dbSNP
rs1281702551 1498 dbSNP
rs1350726582 1499 dbSNP
rs1468805290 1499 dbSNP
rs1208607562 1500 dbSNP
rs1235314361 1501 dbSNP
rs1174939313 1502 dbSNP
rs1204426612 1502 dbSNP
rs35267229 1502 dbSNP
rs78425178 1503 dbSNP
rs564552230 1513 dbSNP
rs1058241 1514 dbSNP
rs201528092 1514 dbSNP
rs1308003840 1521 dbSNP
rs1294664928 1524 dbSNP
rs947374058 1546 dbSNP
rs1186759807 1549 dbSNP
rs1043321776 1550 dbSNP
rs903427666 1559 dbSNP
rs1403285332 1564 dbSNP
rs1172108093 1565 dbSNP
rs1447468575 1565 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 10940.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' augcggucaguuaugGAACACu 5'
                         |||||| 
Target 5' -------ucuaaauaCUUGUGa 3'
 		1 - 15
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000401707.2 | 3UTR | UCUAAAUACUUGUGAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
83 hsa-miR-4457 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT098032 SOBP sine oculis binding protein homolog 2 2
MIRT202580 PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 2 6
MIRT247137 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT349266 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT363756 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT443586 FAM84B family with sequence similarity 84 member B 2 2
MIRT452333 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT453864 ZBTB40 zinc finger and BTB domain containing 40 2 4
MIRT471486 PDE4D phosphodiesterase 4D 2 4
MIRT476290 GMFB glia maturation factor beta 2 8
MIRT479897 CCDC117 coiled-coil domain containing 117 2 4
MIRT484251 ANK1 ankyrin 1 2 2
MIRT491473 TMEM214 transmembrane protein 214 2 2
MIRT493804 GAN gigaxonin 2 6
MIRT499252 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT502271 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 4
MIRT504651 RPL9 ribosomal protein L9 2 6
MIRT505211 UBN2 ubinuclein 2 2 8
MIRT508952 SNRPB small nuclear ribonucleoprotein polypeptides B and B1 2 4
MIRT512691 POP1 POP1 homolog, ribonuclease P/MRP subunit 2 2
MIRT513320 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT513870 HOXA5 homeobox A5 2 2
MIRT517342 ZNF529 zinc finger protein 529 2 4
MIRT518947 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT520867 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT528325 GIGYF2 GRB10 interacting GYF protein 2 2 2
MIRT531990 SLCO1B3 solute carrier organic anion transporter family member 1B3 2 2
MIRT533298 USP46 ubiquitin specific peptidase 46 2 2
MIRT545257 TRIM36 tripartite motif containing 36 2 4
MIRT547038 POGZ pogo transposable element derived with ZNF domain 2 2
MIRT556103 MOAP1 modulator of apoptosis 1 2 2
MIRT558321 DR1 down-regulator of transcription 1 2 2
MIRT558521 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT560906 TMED10 transmembrane p24 trafficking protein 10 2 2
MIRT568448 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT570586 OTUD7B OTU deubiquitinase 7B 2 2
MIRT572799 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT573863 C9orf78 chromosome 9 open reading frame 78 2 2
MIRT575058 P2ry1 purinergic receptor P2Y, G-protein coupled 1 2 5
MIRT609931 SLC38A1 solute carrier family 38 member 1 2 4
MIRT610836 ZNF585A zinc finger protein 585A 2 4
MIRT611474 P2RY1 purinergic receptor P2Y1 2 7
MIRT613569 YY2 YY2 transcription factor 2 2
MIRT618626 GREB1 growth regulation by estrogen in breast cancer 1 2 2
MIRT620606 SAP30 Sin3A associated protein 30 2 2
MIRT621017 CLSTN3 calsyntenin 3 2 4
MIRT635314 FAM179A TOG array regulator of axonemal microtubules 2 2 2
MIRT635919 GLTSCR2 NOP53 ribosome biogenesis factor 2 2
MIRT640598 TM9SF4 transmembrane 9 superfamily member 4 2 2
MIRT641784 YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta 2 4
MIRT644067 IQCE IQ motif containing E 2 2
MIRT648288 TRAPPC2L trafficking protein particle complex 2 like 2 2
MIRT658085 FOXR2 forkhead box R2 2 2
MIRT659077 DEPTOR DEP domain containing MTOR interacting protein 2 2
MIRT665307 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT665975 SYTL4 synaptotagmin like 4 2 2
MIRT666302 SLC25A25 solute carrier family 25 member 25 2 2
MIRT674906 RASSF9 Ras association domain family member 9 2 2
MIRT680086 THAP1 THAP domain containing 1 2 2
MIRT681488 DIP2A disco interacting protein 2 homolog A 2 2
MIRT691244 DFNB59 pejvakin 2 2
MIRT692362 AGTRAP angiotensin II receptor associated protein 2 2
MIRT693035 MB21D1 Mab-21 domain containing 1 2 2
MIRT693837 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT694479 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2 2
MIRT696070 ZNF264 zinc finger protein 264 2 2
MIRT696578 TTC21B tetratricopeptide repeat domain 21B 2 2
MIRT696760 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 2
MIRT697307 ZNF652 zinc finger protein 652 2 2
MIRT700152 RNF115 ring finger protein 115 2 2
MIRT701056 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT701198 OTUD3 OTU deubiquitinase 3 2 2
MIRT701335 NSD1 nuclear receptor binding SET domain protein 1 2 2
MIRT702656 ITGA3 integrin subunit alpha 3 2 2
MIRT703618 FBXO45 F-box protein 45 2 2
MIRT704673 CHTOP chromatin target of PRMT1 2 2
MIRT708894 ZNF780A zinc finger protein 780A 2 2
MIRT711620 DGKH diacylglycerol kinase eta 2 2
MIRT713745 TMEM81 transmembrane protein 81 2 2
MIRT719712 CD101 CD101 molecule 2 2
MIRT720294 DLGAP3 DLG associated protein 3 2 2
MIRT722606 CCDC152 coiled-coil domain containing 152 2 2
MIRT724566 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4457 Dabrafenib 44462760 NSC764134 approved sensitive cell line (A375)
hsa-miR-4457 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-4457 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-4457 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)

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