miRTarBase - #MIRT512974


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pre-miRNA Information
pre-miRNA hsa-mir-4672   
Genomic Coordinates chr9: 127869415 - 127869495
Description Homo sapiens miR-4672 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4672
Sequence 51| UUACACAGCUGGACAGAGGCA |71
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1234304182 2 dbSNP
rs1012722802 6 dbSNP
rs1212523496 9 dbSNP
rs1027978850 10 dbSNP
rs1212553533 14 dbSNP
rs895240447 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PPP1R14C   
Synonyms CPI17-like, KEPI, NY-BR-81
Description protein phosphatase 1 regulatory inhibitor subunit 14C
Transcript NM_030949   
Expression
Putative miRNA Targets on PPP1R14C
3'UTR of PPP1R14C
(miRNA target sites are highlighted)		 
>PPP1R14C|NM_030949|3'UTR
   1 TTCTGGAACAGGGTGAAACTCTCCCAGAGACGAAGAAAGAGTCCTGGGATTTGTACTTCATGAAGACTTTTGTGAAAGAA
  81 TAGGTGTCCTTATGAACAACGTTTTTGTTTTTTTTTTTTTCTTTTTTGGTGTGAAGGTGGGGGGGTCTATTAGACATTTA
 161 TTCAAGAGCGTTCTTTTTTTGGTTTTAAAGGTTTTTGTTAATGTAATATTTTAATAGCAAAGATATCATGACTCTAGCCA
 241 CAGCCTAACCAAGGATTATCAAAGGAGGTGGACACTCAAGGAAGGGCCACGCCAGGCTGCGTTTCCTGCAAGGACTCAGA
 321 TGTTCAGTACCTTATGATACAGGGAAGATAGTTTTCTTACAAGTAGTTTGGTAATATTTTTTTTCTTAAGTTGTACATTT
 401 GACTCAGCTGTCAAATTTCTCACACTTGTATATATCTACACACAACTAAGTTAAAATGTTGATGTGAGTTTTATTTCACA
 481 TGGATGGAATAAACTTGTGGTTGTCCTTTAACTGGAGGTCCCAGCACATGTGTTTTCAAGAGGCCACTAGGCATTCTTCA
 561 CTGAGTGCTGCTGACTTCAACGTTCACTTTATGCACCAAAGTGAAAGAATTCAGTGTATCCGTTATTTTAATGCACTACA
 641 CCACAGAAATGTTAAGTTGGTCAAGGGCTTAATTTATGGAATTTCTATTATTTCATTGGTTGGGATGCTTTGCCAGGTCA
 721 TGTGCTTATTGTCTCATTTTGTAGTCTTTTAAAGTTGTATGAACCCTTAATTTGAAGAACTAACTTGATTTCTAGAGAAA
 801 TATCCACACTATCTCAGTGGTATTTTGCATTGGAAAAAGGAAGCACTGTGTAGCAGTGAATTGTCTGCTTTCCACCGAGT
 881 ACTGTGTTTATTCTCTCTCCAGGAAAGCAGATCAAAAGAAAGTTAGCAGATCGAGTGTCTTCTTCCTTAGAAATAGGTTC
 961 TGGTAGCTTCTGTGCCTGGGTAGTATCAGACCAGTGGGAGTAAACCGAGTGTTAAGTGTCAAGGTGAGAAAGCCTCACAT
1041 TCTCTCAAGACAGTTGCTCTAGGAGCTGAGTTGCTGGTTTGGAAGTGTGGAGATTGCATTTCTGGCTTCTCTCAATGGCT
1121 TGTGTTGAGGACTCTGGGTGCTCCTGGCCCTAATTGTGCACCCTGATCCCCGTGCTTGGAGCTAGGCCTGGTGGCGTGCT
1201 CTAGCCCTCTCAGTTACCAGCTCTTTGGAGAAGGATCAAAATTCAGATGGAATGTGGGATGGGTAATAGGTGAGAGTAGA
1281 AACCCTTCCCTCCAGGAGGCCCCCGCTGACTCCCACAGAAACCCACCTACCATAAGATGTCTTCAGGTGGCCTTGTCCAA
1361 GGATGGGGGTCAGGCATTTTATATCAAGGGTGCTCTGAACATATTTTATTTTTTAAAAAAACTATGTTTGTGAATTTTGC
1441 GTATACTGGCAAGCTTTTGAAAATGTATTTAATTTTGTATTGTTTACCAATGATTTATTTACAAGATATTTACTCAAATA
1521 AATGGAGCTGCTTACAAGCCTGTTGACATGTGTGGCTTGCACAACACGTTAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acggagacagGUCGACACAUu 5'
                    || ||||||| 
Target 5' aaaaaggaagCA-CTGTGTAg 3'
 834 - 853 142.00 -10.00
2 
miRNA  3' acGGAGACAGG----UC--GACACAuu 5'
            |: || |||    ||  ||||||  
Target 5' gtCTGCTTTCCACCGAGTACTGTGTtt 3'
 863 - 889 131.00 -12.50
3 
miRNA  3' acGGAGACAGGUCGACACAUu 5'
            |:||||| |  ||| ||| 
Target 5' agCTTCTGTGC--CTGGGTAg 3'
 965 - 983 131.00 -16.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM3674577 1 COSMIC
COSN30533752 19 COSMIC
COSN31587601 20 COSMIC
COSN30518180 36 COSMIC
COSN28834564 102 COSMIC
COSN27563882 107 COSMIC
COSN19732811 109 COSMIC
COSN30126752 119 COSMIC
COSN30117137 120 COSMIC
COSN20050188 121 COSMIC
COSN20103491 121 COSMIC
COSN15664691 122 COSMIC
COSN30166360 331 COSMIC
COSN30175653 385 COSMIC
COSN31584613 427 COSMIC
COSN31486911 462 COSMIC
COSN22738209 588 COSMIC
COSN29140719 762 COSMIC
COSN32064125 823 COSMIC
COSN2147316 829 COSMIC
COSN32055782 985 COSMIC
COSN15204591 1173 COSMIC
COSN20601891 1238 COSMIC
COSN22703611 1413 COSMIC
COSN31527497 1428 COSMIC
COSN31564701 1450 COSMIC
COSN14721309 1482 COSMIC
COSN2147317 1515 COSMIC
rs3734729 912 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs569188862 10 dbSNP
rs1433071350 13 dbSNP
rs369588136 14 dbSNP
rs1486521676 22 dbSNP
rs1375082774 23 dbSNP
rs771689206 25 dbSNP
rs772771016 26 dbSNP
rs1395554683 28 dbSNP
rs558209998 29 dbSNP
rs116775070 32 dbSNP
rs748751865 33 dbSNP
rs776682081 33 dbSNP
rs1235502447 37 dbSNP
rs759603372 39 dbSNP
rs776125231 43 dbSNP
rs540384661 44 dbSNP
rs762970894 49 dbSNP
rs977933922 55 dbSNP
rs1413019619 64 dbSNP
rs1364101990 77 dbSNP
rs1289513665 79 dbSNP
rs925520217 83 dbSNP
rs1343628208 89 dbSNP
rs1259716073 94 dbSNP
rs1491404360 101 dbSNP
rs66951687 101 dbSNP
rs773053781 101 dbSNP
rs11759638 102 dbSNP
rs201048948 102 dbSNP
rs989816112 103 dbSNP
rs1189770217 106 dbSNP
rs371776186 107 dbSNP
rs13216807 108 dbSNP
rs1491240577 108 dbSNP
rs369389461 108 dbSNP
rs536454710 108 dbSNP
rs878873084 108 dbSNP
rs1491289174 109 dbSNP
rs75930338 109 dbSNP
rs796498619 110 dbSNP
rs911119936 111 dbSNP
rs942419835 112 dbSNP
rs1441379463 113 dbSNP
rs1038425571 114 dbSNP
rs1463523098 114 dbSNP
rs898278566 115 dbSNP
rs1174021114 119 dbSNP
rs796608308 120 dbSNP
rs114874423 121 dbSNP
rs1193822923 121 dbSNP
rs929705582 121 dbSNP
rs200986997 122 dbSNP
rs78306364 122 dbSNP
rs1382107229 128 dbSNP
rs1399685235 129 dbSNP
rs1321071931 132 dbSNP
rs1367267714 133 dbSNP
rs1226829979 138 dbSNP
rs1438386414 138 dbSNP
rs1239234634 139 dbSNP
rs146050881 139 dbSNP
rs776049060 139 dbSNP
rs377647392 140 dbSNP
rs1331516868 141 dbSNP
rs770032264 142 dbSNP
rs1235652631 144 dbSNP
rs113912908 145 dbSNP
rs1259253920 146 dbSNP
rs1350028023 147 dbSNP
rs1460044184 154 dbSNP
rs1209456352 162 dbSNP
rs1270505813 164 dbSNP
rs1173678995 167 dbSNP
rs780396442 169 dbSNP
rs1453489300 170 dbSNP
rs1045866489 171 dbSNP
rs573370704 175 dbSNP
rs1197213155 177 dbSNP
rs1421213083 180 dbSNP
rs907047353 182 dbSNP
rs542386408 186 dbSNP
rs1251902157 189 dbSNP
rs1195781708 190 dbSNP
rs562489165 202 dbSNP
rs1268471148 217 dbSNP
rs1003445305 219 dbSNP
rs531248626 223 dbSNP
rs1055672032 227 dbSNP
rs577408777 258 dbSNP
rs1273232849 259 dbSNP
rs898414359 263 dbSNP
rs1240953594 266 dbSNP
rs995935990 267 dbSNP
rs1336075971 276 dbSNP
rs1200548240 284 dbSNP
rs1034649678 289 dbSNP
rs574311784 290 dbSNP
rs539904515 291 dbSNP
rs1159294446 292 dbSNP
rs1011606922 301 dbSNP
rs191513290 302 dbSNP
rs560024669 306 dbSNP
rs1325182919 310 dbSNP
rs967472320 311 dbSNP
rs1391181152 321 dbSNP
rs964241092 334 dbSNP
rs868494954 338 dbSNP
rs532111305 341 dbSNP
rs1260159065 348 dbSNP
rs1188752290 351 dbSNP
rs1305063735 360 dbSNP
rs1335403646 370 dbSNP
rs998899761 374 dbSNP
rs543530467 376 dbSNP
rs1030844582 377 dbSNP
rs1259994473 377 dbSNP
rs369337730 377 dbSNP
rs1290318430 381 dbSNP
rs1226329194 382 dbSNP
rs1357300121 386 dbSNP
rs1293756514 387 dbSNP
rs1332834076 388 dbSNP
rs1413659226 388 dbSNP
rs1044672 397 dbSNP
rs1319685633 398 dbSNP
rs12110655 400 dbSNP
rs1266602476 405 dbSNP
rs1158910534 406 dbSNP
rs755200172 413 dbSNP
rs1455915567 414 dbSNP
rs1420692691 429 dbSNP
rs1489666537 438 dbSNP
rs958266413 443 dbSNP
rs1235844738 444 dbSNP
rs1447855252 450 dbSNP
rs183980153 451 dbSNP
rs1206590091 463 dbSNP
rs1336621100 465 dbSNP
rs912913627 469 dbSNP
rs756952893 474 dbSNP
rs1354165305 478 dbSNP
rs1271490683 481 dbSNP
rs1227449974 489 dbSNP
rs964291178 496 dbSNP
rs981220950 510 dbSNP
rs1350954671 513 dbSNP
rs1318075918 522 dbSNP
rs567490614 529 dbSNP
rs937214068 538 dbSNP
rs1055534276 539 dbSNP
rs781540072 544 dbSNP
rs879006518 544 dbSNP
rs931264801 552 dbSNP
rs1163986964 553 dbSNP
rs1412243049 560 dbSNP
rs1368991885 571 dbSNP
rs748281757 583 dbSNP
rs1296262045 602 dbSNP
rs1186968402 606 dbSNP
rs1395990431 611 dbSNP
rs1253469186 615 dbSNP
rs887124692 617 dbSNP
rs1410631779 622 dbSNP
rs1008638483 623 dbSNP
rs563428908 626 dbSNP
rs139879322 633 dbSNP
rs938888909 635 dbSNP
rs549247344 637 dbSNP
rs373546756 639 dbSNP
rs1236091096 642 dbSNP
rs769992209 646 dbSNP
rs1304698731 651 dbSNP
rs1436131869 660 dbSNP
rs1348645996 678 dbSNP
rs1056357105 683 dbSNP
rs1225653652 688 dbSNP
rs755578237 692 dbSNP
rs780026687 693 dbSNP
rs553758974 700 dbSNP
rs1212364663 701 dbSNP
rs997048744 706 dbSNP
rs754844523 713 dbSNP
rs1190415565 714 dbSNP
rs1205414038 716 dbSNP
rs958421642 719 dbSNP
rs1253613415 722 dbSNP
rs1484366576 732 dbSNP
rs537901943 734 dbSNP
rs1012220917 742 dbSNP
rs1256712732 748 dbSNP
rs9480066 759 dbSNP
rs1021589253 766 dbSNP
rs1212386932 768 dbSNP
rs967102672 773 dbSNP
rs1389293839 781 dbSNP
rs1348167742 788 dbSNP
rs773085377 795 dbSNP
rs998845924 804 dbSNP
rs981511537 817 dbSNP
rs1170709506 820 dbSNP
rs571572334 821 dbSNP
rs1373869188 830 dbSNP
rs573909856 831 dbSNP
rs534241280 833 dbSNP
rs1306276547 836 dbSNP
rs1436589340 843 dbSNP
rs1376326152 846 dbSNP
rs747873898 848 dbSNP
rs1412960172 851 dbSNP
rs1303534298 854 dbSNP
rs1177564113 863 dbSNP
rs76967679 867 dbSNP
rs1472256515 875 dbSNP
rs1008091204 877 dbSNP
rs1381002932 878 dbSNP
rs1485687949 880 dbSNP
rs3832442 882 dbSNP
rs750326579 882 dbSNP
rs762868254 883 dbSNP
rs1318353991 887 dbSNP
rs973928719 892 dbSNP
rs553922557 900 dbSNP
rs1224631059 909 dbSNP
rs573930968 910 dbSNP
rs919835728 911 dbSNP
rs3734729 912 dbSNP
rs1276261637 913 dbSNP
rs556031312 913 dbSNP
rs1302305238 915 dbSNP
rs1345323916 923 dbSNP
rs919764009 928 dbSNP
rs1208767740 933 dbSNP
rs1159579768 934 dbSNP
rs1347168598 934 dbSNP
rs1256041408 935 dbSNP
rs776712392 940 dbSNP
rs928436022 941 dbSNP
rs1409700505 942 dbSNP
rs370654685 953 dbSNP
rs1166944790 954 dbSNP
rs1475479855 966 dbSNP
rs867143313 967 dbSNP
rs3734730 985 dbSNP
rs551318535 1001 dbSNP
rs1486651819 1004 dbSNP
rs759210701 1007 dbSNP
rs908453908 1008 dbSNP
rs61646299 1010 dbSNP
rs147691798 1012 dbSNP
rs1266603979 1017 dbSNP
rs1449774617 1020 dbSNP
rs141009674 1027 dbSNP
rs1312169224 1033 dbSNP
rs1393464226 1040 dbSNP
rs1414094662 1041 dbSNP
rs769774637 1043 dbSNP
rs1177124150 1051 dbSNP
rs903431768 1060 dbSNP
rs1360955776 1070 dbSNP
rs899807843 1073 dbSNP
rs541368960 1079 dbSNP
rs1327668657 1086 dbSNP
rs868249361 1093 dbSNP
rs775641066 1097 dbSNP
rs1367765581 1105 dbSNP
rs996954082 1108 dbSNP
rs149819781 1114 dbSNP
rs1051753097 1116 dbSNP
rs890556757 1124 dbSNP
rs1447253991 1125 dbSNP
rs1246645056 1134 dbSNP
rs1008031874 1135 dbSNP
rs9480070 1138 dbSNP
rs899698713 1142 dbSNP
rs1010141184 1144 dbSNP
rs1298388735 1146 dbSNP
rs1026883217 1150 dbSNP
rs549456081 1153 dbSNP
rs971368172 1154 dbSNP
rs774908806 1155 dbSNP
rs762056741 1157 dbSNP
rs1035331576 1161 dbSNP
rs145825255 1162 dbSNP
rs879181221 1167 dbSNP
rs368620838 1172 dbSNP
rs1396449104 1173 dbSNP
rs919671226 1183 dbSNP
rs991610756 1188 dbSNP
rs760234557 1191 dbSNP
rs1481887178 1194 dbSNP
rs148998521 1196 dbSNP
rs560452433 1197 dbSNP
rs943968092 1202 dbSNP
rs924885700 1208 dbSNP
rs1040961616 1212 dbSNP
rs921267042 1219 dbSNP
rs1330352186 1224 dbSNP
rs1298884104 1231 dbSNP
rs932602358 1243 dbSNP
rs934870551 1247 dbSNP
rs1351018527 1255 dbSNP
rs1306883887 1270 dbSNP
rs571332971 1272 dbSNP
rs796557613 1273 dbSNP
rs1210562777 1293 dbSNP
rs1250887133 1300 dbSNP
rs9397229 1301 dbSNP
rs1009761132 1305 dbSNP
rs1042936793 1306 dbSNP
rs1151 1310 dbSNP
rs1482088964 1315 dbSNP
rs115601588 1316 dbSNP
rs1201286785 1323 dbSNP
rs1344576209 1324 dbSNP
rs1039568704 1327 dbSNP
rs1329780322 1332 dbSNP
rs1033859530 1333 dbSNP
rs536397676 1339 dbSNP
rs1407476183 1342 dbSNP
rs1012535426 1349 dbSNP
rs532667342 1351 dbSNP
rs1356863643 1359 dbSNP
rs1334209141 1377 dbSNP
rs995330611 1380 dbSNP
rs576022674 1389 dbSNP
rs765880480 1391 dbSNP
rs1399544750 1401 dbSNP
rs1171192759 1402 dbSNP
rs1389969116 1402 dbSNP
rs1413377460 1404 dbSNP
rs1159137127 1406 dbSNP
rs753306137 1415 dbSNP
rs1026759440 1416 dbSNP
rs952557903 1417 dbSNP
rs1442074560 1424 dbSNP
rs1026748780 1425 dbSNP
rs1206704197 1425 dbSNP
rs982524983 1427 dbSNP
rs1015863950 1431 dbSNP
rs1004048350 1440 dbSNP
rs1035368181 1441 dbSNP
rs758895211 1442 dbSNP
rs1338371525 1444 dbSNP
rs1225983300 1448 dbSNP
rs976671202 1449 dbSNP
rs1287127456 1452 dbSNP
rs766671389 1455 dbSNP
rs921172295 1463 dbSNP
rs778791484 1464 dbSNP
rs989461148 1466 dbSNP
rs1163912096 1470 dbSNP
rs1230142144 1487 dbSNP
rs538748783 1489 dbSNP
rs1271271766 1491 dbSNP
rs189097201 1498 dbSNP
rs1195660598 1503 dbSNP
rs1450287153 1505 dbSNP
rs1247256374 1507 dbSNP
rs945465238 1524 dbSNP
rs1042450738 1529 dbSNP
rs1469771385 1536 dbSNP
rs145900828 1539 dbSNP
rs1353711075 1548 dbSNP
rs912145088 1548 dbSNP
rs943388122 1549 dbSNP
rs758114394 1555 dbSNP
rs1055344505 1563 dbSNP
rs1297342082 1564 dbSNP
rs777565075 1565 dbSNP
rs762698571 1569 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 81706.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acggagacaggucGACACAUu 5'
                       ||||||| 
Target 5' -------------CUGUGUAg 3'
 		1 - 8
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 81706.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065668. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acggagacaggucGACACAUu 5'
                       ||||||| 
Target 5' -------------CUGUGUAg 3'
 		1 - 8
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000361131.4 | 3UTR | CUGUGUAGCAGUGAAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065668
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_7
Location of target site ENST00000361131.4 | 3UTR | CUGUGUAGCAGUGAAUUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
126 hsa-miR-4672 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT060585 CCND1 cyclin D1 2 2
MIRT063968 ZNF678 zinc finger protein 678 2 2
MIRT078062 PCTP phosphatidylcholine transfer protein 2 2
MIRT084370 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT095611 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT096511 BRIX1 BRX1, biogenesis of ribosomes 2 4
MIRT121793 GRPEL2 GrpE like 2, mitochondrial 2 2
MIRT129470 CHEK1 checkpoint kinase 1 2 4
MIRT149009 PKN2 protein kinase N2 2 2
MIRT169592 PNRC1 proline rich nuclear receptor coactivator 1 2 2
MIRT177382 WAC WW domain containing adaptor with coiled-coil 2 4
MIRT214659 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT322680 BAG4 BCL2 associated athanogene 4 2 4
MIRT332490 CD81 CD81 molecule 2 6
MIRT338986 CPSF6 cleavage and polyadenylation specific factor 6 2 2
MIRT353814 PCBP1 poly(rC) binding protein 1 2 2
MIRT449368 ANTXR2 anthrax toxin receptor 2 2 2
MIRT459867 KIAA1191 KIAA1191 2 2
MIRT466272 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT467049 SRSF1 serine and arginine rich splicing factor 1 2 4
MIRT469925 PTPRJ protein tyrosine phosphatase, receptor type J 2 6
MIRT470361 PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon 2 2
MIRT471076 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta 2 2
MIRT472472 NAP1L1 nucleosome assembly protein 1 like 1 2 4
MIRT478137 DHX33 DEAH-box helicase 33 2 2
MIRT479414 CDKN1B cyclin dependent kinase inhibitor 1B 2 4
MIRT496523 ID2 inhibitor of DNA binding 2, HLH protein 2 2
MIRT510371 ZNF703 zinc finger protein 703 2 6
MIRT512861 TESK2 testis-specific kinase 2 2 2
MIRT512974 PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C 2 4
MIRT513313 ASB6 ankyrin repeat and SOCS box containing 6 2 4
MIRT521882 PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 2 4
MIRT522184 NR2C2 nuclear receptor subfamily 2 group C member 2 2 4
MIRT528381 TRAF3IP1 TRAF3 interacting protein 1 2 2
MIRT532412 ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2 2
MIRT533027 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT533438 TRPC5 transient receptor potential cation channel subfamily C member 5 2 2
MIRT533919 TATDN2 TatD DNase domain containing 2 2 2
MIRT537568 ESYT2 extended synaptotagmin 2 2 2
MIRT538955 BMP2K BMP2 inducible kinase 2 2
MIRT539042 ATXN1L ataxin 1 like 2 4
MIRT539626 CD19 CD19 molecule 2 8
MIRT545720 SPTLC2 serine palmitoyltransferase long chain base subunit 2 2 2
MIRT546013 WDR26 WD repeat domain 26 2 4
MIRT549703 RBM23 RNA binding motif protein 23 2 4
MIRT551162 UBTF upstream binding transcription factor, RNA polymerase I 2 4
MIRT552078 MESDC2 mesoderm development LRP chaperone 2 4
MIRT552530 ZIC5 Zic family member 5 2 2
MIRT552670 YY1 YY1 transcription factor 2 4
MIRT554225 SLC24A2 solute carrier family 24 member 2 2 2
MIRT554356 SFXN5 sideroflexin 5 2 4
MIRT555279 PPTC7 PTC7 protein phosphatase homolog 2 4
MIRT555642 PHF13 PHD finger protein 13 2 2
MIRT558365 DIDO1 death inducer-obliterator 1 2 4
MIRT558630 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT559238 BEND4 BEN domain containing 4 2 2
MIRT559556 ARF6 ADP ribosylation factor 6 2 2
MIRT561686 RAB1A RAB1A, member RAS oncogene family 2 2
MIRT562668 ANKRD40 ankyrin repeat domain 40 2 2
MIRT565689 SESN3 sestrin 3 2 2
MIRT566238 PTBP3 polypyrimidine tract binding protein 3 2 2
MIRT567699 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 2
MIRT573858 C9orf78 chromosome 9 open reading frame 78 2 2
MIRT574156 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT575869 Kif5c kinesin family member 5C 2 3
MIRT576180 Muc15 mucin 15 2 5
MIRT606886 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 6
MIRT606908 ZBTB20 zinc finger and BTB domain containing 20 2 4
MIRT606914 MUC15 mucin 15, cell surface associated 2 7
MIRT607250 FAM216B family with sequence similarity 216 member B 2 4
MIRT607562 KIF5C kinesin family member 5C 2 3
MIRT609075 SMIM15 small integral membrane protein 15 2 6
MIRT609160 ZNF415 zinc finger protein 415 2 4
MIRT609360 ACOT2 acyl-CoA thioesterase 2 2 2
MIRT609799 ZDHHC17 zinc finger DHHC-type containing 17 2 2
MIRT610368 GRIPAP1 GRIP1 associated protein 1 2 2
MIRT611341 KIAA2018 upstream transcription factor family member 3 2 4
MIRT611732 PRSS23 protease, serine 23 2 4
MIRT611826 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT611906 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT612377 TFCP2 transcription factor CP2 2 4
MIRT613482 LYRM7 LYR motif containing 7 2 2
MIRT613641 DUSP18 dual specificity phosphatase 18 2 4
MIRT613822 LANCL3 LanC like 3 2 4
MIRT613863 CBY3 chibby family member 3 2 4
MIRT613871 TMEM51 transmembrane protein 51 2 2
MIRT614688 TWIST1 twist family bHLH transcription factor 1 2 2
MIRT615044 DCP2 decapping mRNA 2 2 2
MIRT616872 ARPC1B actin related protein 2/3 complex subunit 1B 2 4
MIRT617012 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT618524 CCDC174 coiled-coil domain containing 174 2 2
MIRT621827 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT622108 SPRY4 sprouty RTK signaling antagonist 4 2 6
MIRT623111 NFATC2 nuclear factor of activated T-cells 2 2 2
MIRT626102 GNAI1 G protein subunit alpha i1 2 4
MIRT626416 ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2 2
MIRT627656 RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component 2 2
MIRT628333 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT629334 DNTTIP2 deoxynucleotidyltransferase terminal interacting protein 2 2 2
MIRT630426 LMX1A LIM homeobox transcription factor 1 alpha 2 2
MIRT630707 GDNF glial cell derived neurotrophic factor 2 2
MIRT632568 POLQ DNA polymerase theta 2 2
MIRT632798 KIAA2022 neurite extension and migration factor 2 2
MIRT634125 ZDHHC21 zinc finger DHHC-type containing 21 2 4
MIRT634299 SP1 Sp1 transcription factor 2 2
MIRT634406 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT636827 FSIP2 fibrous sheath interacting protein 2 2 2
MIRT638270 SH3PXD2A SH3 and PX domains 2A 2 2
MIRT643060 CCDC149 coiled-coil domain containing 149 2 2
MIRT646160 SLC22A1 solute carrier family 22 member 1 2 2
MIRT648243 AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 2 2
MIRT663402 SYT17 synaptotagmin 17 2 6
MIRT666042 STON2 stonin 2 2 2
MIRT670698 GGA2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 2 2
MIRT672337 TMEM79 transmembrane protein 79 2 4
MIRT672628 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT685229 F2RL1 F2R like trypsin receptor 1 2 2
MIRT693225 KIAA0907 KIAA0907 2 4
MIRT696142 RAB11FIP3 RAB11 family interacting protein 3 2 2
MIRT697908 TXNRD1 thioredoxin reductase 1 2 2
MIRT705315 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT712264 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT714080 ZNF532 zinc finger protein 532 2 2
MIRT715104 SORBS3 sorbin and SH3 domain containing 3 2 2
MIRT722237 RBM41 RNA binding motif protein 41 2 2
MIRT725113 SYNRG synergin gamma 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4672 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4672 Paclitaxel 36314 NSC125973 approved sensitive High Endometrial Serous Carcinoma cell line (USPC1)
hsa-miR-4672 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4672 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-4672 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4672 Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-4672 Oxaliplatin 6857599 NSC266046 approved sensitive cell line (HCT116)
hsa-miR-4672 Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-4672 Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-4672 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4672 Platinum 23939 resistant tissue (non-small cell lung cancer)
hsa-miR-4672 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (100 ng/ml)
hsa-miR-4672 Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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