miRTarBase - #MIRT517637


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pre-miRNA Information
pre-miRNA hsa-mir-500b   
Genomic Coordinates chrX: 50010672 - 50010750
Description Homo sapiens miR-500b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-500b-3p
Sequence 51| GCACCCAGGCAAGGAUUCUG |70
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs782140253 8 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol ZNF491   
Synonyms -
Description zinc finger protein 491
Transcript NM_152356   
Expression
Putative miRNA Targets on ZNF491
3'UTR of ZNF491
(miRNA target sites are highlighted)		 
>ZNF491|NM_152356|3'UTR
   1 GAGAAATGCTATTTTTTAATTTTTATTTTAATAGAGACAGGGTCTCACTATCTTGTCCAGGTTGGTCTTGAACTCCTGGC
  81 CTCAAGCATCCCTCCCAGCTTGAAGTGTCAATAAAGGAAGGCAATAAAATGTAGAGATGGAGTTAGGTGATGCCACGCTG
 161 GGATTCACTGGTGGCCTATCTTACATATGATTTCGAAGGCAGACATGAGGAAGGCCTTAGTCACATTTTAGAGCCAGCCA
 241 AATTCACATGGGCTGTGTGGCCCCCTGATTCTAGCCCATTTTCCTGATTCTCTGGCTTGTCAATCAAGAGTATCCTCCAA
 321 ATCTCTTGACTTTCCTTTTTTCAGAGGTGTAGGTTTCCAAAGATGTCCCCAGAAGCTCCACATTCAAGTTCTATCTACAG
 401 TTTGGTTTTTCTTTAAGTATTGTAATGTACATACCAGAGAGATAATGCAGACTGTCATGGGTGGGGAATGTTCTCTGATG
 481 CTCAACTCCCCTAGTCTGCAGATTGAGTTGGTAGGAGGTGTGATTTGTTTACATGCACCTTTGTTCCTGCTGGTAGTGAC
 561 CTTGTTCTTGATTCAGCCTGACAGCTACTATGCTGCCATCAGAACCAACTTGATGAGAGCTCTGCTGCCCTGTGCAGTGA
 641 CTGGTCTCATCCAGGACTCTCATGTGAGAAGGAACACCTTGCTCTGGTCAGGAAATGTCCAGTGTTTCCTGTTATCCACA
 721 GGAGAATGTAATGCCTCAGTTCATTTTCAGTTATCTTTGATTATATGTGATTGACAATGTGTATTTTTGAGGGAGCAAAG
 801 ATTTCTGTACATATTTCTTAAAAATAGTTTATTCAGCTGGGTGCAGTGGCTCATGCCTGTAACCCCAGCACTTTGGGAGG
 881 CCGAGGTGGGCGGATCACGAGGTCAGGAGTTTGAGACTAGCCTGGCCAACACAGTGAAACCCCATCTCTACTAAAAGTAC
 961 CAAAGTTAGCCGGGTGTGGTGGTGGATACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCCTGAACCTG
1041 GGAGGTGGAGGTTGCAGTGAGCCAAGATCACGCCACTGTACTCCAGCCTGGACAAGAGAGCAATACTCTGTCTCAAAAAA
1121 AAAAAAAAAGGTTTATTCACTGTTTTTCAGTTGTGTACTTGCAAATGTTTTTCTCTTTTTTTTGTATACTGAGAAGCTCT
1201 ATTAAAATATCCCTTGTCAACATG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gucUUAGGAACG--GACCCACg 5'
             |:|:: | |  ||||||| 
Target 5' aatAGTTTATTCAGCTGGGTGc 3'
 823 - 844 147.00 -16.40
2 
miRNA  3' guCUUAG-GAAC--GGACCCACg 5'
            ||||| | ||  |||||| | 
Target 5' gaGAATCTCCTGAACCTGGGAGg 3'
 1023 - 1045 132.00 -17.70
3 
miRNA  3' gucUUAGG---AACGGACCCACg 5'
             |||:|   | | ||| ||| 
Target 5' ccaAATTCACATGGGCTGTGTGg 3'
 238 - 260 121.00 -7.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20115448 18 COSMIC
COSN7353864 18 COSMIC
COSN30243254 25 COSMIC
COSN30114968 32 COSMIC
COSN21014424 68 COSMIC
COSN30501548 72 COSMIC
COSN15627092 91 COSMIC
COSN30166546 107 COSMIC
COSN31519228 121 COSMIC
COSN30008202 127 COSMIC
COSN30542031 157 COSMIC
COSN31531143 158 COSMIC
COSN30133253 170 COSMIC
COSN30123735 195 COSMIC
COSN30513462 234 COSMIC
COSN17132057 270 COSMIC
COSN31607329 291 COSMIC
COSN15627093 293 COSMIC
COSN32062817 306 COSMIC
COSN30169410 315 COSMIC
COSN31523796 321 COSMIC
COSN15627094 340 COSMIC
COSN31486194 605 COSMIC
COSN31539926 621 COSMIC
COSN31526906 629 COSMIC
COSN27820542 650 COSMIC
COSN31518882 652 COSMIC
COSN28653982 673 COSMIC
COSN30532721 715 COSMIC
COSN30113115 725 COSMIC
COSN30136474 801 COSMIC
COSN17183315 802 COSMIC
rs11670714 797 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs745896290 2 dbSNP
rs911112931 8 dbSNP
rs1164497021 10 dbSNP
rs398033931 12 dbSNP
rs71166630 12 dbSNP
rs780328290 16 dbSNP
rs746926767 18 dbSNP
rs1386322639 23 dbSNP
rs768778556 29 dbSNP
rs776498215 32 dbSNP
rs1325396245 33 dbSNP
rs941293293 33 dbSNP
rs879290050 35 dbSNP
rs974045396 43 dbSNP
rs761678253 48 dbSNP
rs1220873013 52 dbSNP
rs1368160696 55 dbSNP
rs188690620 62 dbSNP
rs1438858293 63 dbSNP
rs1045883634 70 dbSNP
rs1445469102 100 dbSNP
rs1321541555 107 dbSNP
rs540569231 110 dbSNP
rs906960344 113 dbSNP
rs779662458 128 dbSNP
rs753335356 139 dbSNP
rs936952668 147 dbSNP
rs1434574350 150 dbSNP
rs561826110 157 dbSNP
rs1055489404 158 dbSNP
rs1415571663 178 dbSNP
rs1425142298 182 dbSNP
rs1220052679 186 dbSNP
rs1004014613 188 dbSNP
rs529120349 195 dbSNP
rs1188814069 210 dbSNP
rs1464106544 210 dbSNP
rs1012230956 225 dbSNP
rs1020560891 236 dbSNP
rs1338162185 239 dbSNP
rs903350779 243 dbSNP
rs574916672 250 dbSNP
rs1010907564 257 dbSNP
rs997699987 265 dbSNP
rs1227983379 272 dbSNP
rs968587749 288 dbSNP
rs1304788074 290 dbSNP
rs974699085 296 dbSNP
rs143242193 305 dbSNP
rs1432105938 308 dbSNP
rs1209131801 309 dbSNP
rs1448521316 314 dbSNP
rs1257222695 325 dbSNP
rs1417007089 330 dbSNP
rs954549718 331 dbSNP
rs1488851449 335 dbSNP
rs987739161 336 dbSNP
rs1483489769 342 dbSNP
rs1236628202 353 dbSNP
rs1208650291 371 dbSNP
rs754552260 372 dbSNP
rs953480490 373 dbSNP
rs1196104699 378 dbSNP
rs1483972595 380 dbSNP
rs986063664 394 dbSNP
rs562644627 398 dbSNP
rs779366312 401 dbSNP
rs961808727 403 dbSNP
rs533073171 418 dbSNP
rs1016204065 423 dbSNP
rs1475088096 425 dbSNP
rs748742158 432 dbSNP
rs1412254515 435 dbSNP
rs1371656322 439 dbSNP
rs974394276 449 dbSNP
rs918545389 450 dbSNP
rs1427117835 455 dbSNP
rs1352248752 459 dbSNP
rs948276492 465 dbSNP
rs1423967877 469 dbSNP
rs929765476 471 dbSNP
rs1045340494 477 dbSNP
rs928222600 481 dbSNP
rs939504439 482 dbSNP
rs551453097 486 dbSNP
rs892553759 487 dbSNP
rs1011031964 489 dbSNP
rs2685687 504 dbSNP
rs899856165 510 dbSNP
rs1271682781 512 dbSNP
rs145515641 519 dbSNP
rs1351451841 521 dbSNP
rs937088494 523 dbSNP
rs1390114651 533 dbSNP
rs1055583939 534 dbSNP
rs1370551831 564 dbSNP
rs1294738085 591 dbSNP
rs892791285 594 dbSNP
rs73922694 603 dbSNP
rs747345164 609 dbSNP
rs567843248 610 dbSNP
rs1008691893 611 dbSNP
rs1412418370 612 dbSNP
rs1014749265 617 dbSNP
rs1417163650 625 dbSNP
rs961761039 631 dbSNP
rs368119675 642 dbSNP
rs536140710 645 dbSNP
rs771262428 646 dbSNP
rs998067718 651 dbSNP
rs1271548380 656 dbSNP
rs973155320 660 dbSNP
rs542756662 661 dbSNP
rs969055626 664 dbSNP
rs980856253 665 dbSNP
rs1259844427 668 dbSNP
rs17001666 673 dbSNP
rs939640993 677 dbSNP
rs1248497566 683 dbSNP
rs577776263 708 dbSNP
rs1369608843 712 dbSNP
rs1452711677 717 dbSNP
rs1436751179 722 dbSNP
rs1052598904 725 dbSNP
rs1172920690 729 dbSNP
rs1451567741 730 dbSNP
rs538750021 739 dbSNP
rs1176658522 742 dbSNP
rs1453930230 748 dbSNP
rs1251159145 750 dbSNP
rs1190763066 760 dbSNP
rs946766384 765 dbSNP
rs553847336 775 dbSNP
rs769138289 776 dbSNP
rs899929040 778 dbSNP
rs1383730262 779 dbSNP
rs1257167433 781 dbSNP
rs572148898 794 dbSNP
rs1016341683 795 dbSNP
rs996825734 796 dbSNP
rs11670714 797 dbSNP
rs1300542867 800 dbSNP
rs1325178790 805 dbSNP
rs1368137094 807 dbSNP
rs890375787 808 dbSNP
rs1317163558 811 dbSNP
rs1008803326 827 dbSNP
rs1439613553 828 dbSNP
rs1303373460 844 dbSNP
rs1014696721 846 dbSNP
rs961875470 855 dbSNP
rs1242708308 856 dbSNP
rs772959030 858 dbSNP
rs562042224 860 dbSNP
rs993520488 868 dbSNP
rs368791247 883 dbSNP
rs951348908 884 dbSNP
rs1292358837 891 dbSNP
rs1467188971 892 dbSNP
rs142532408 893 dbSNP
rs750748710 895 dbSNP
rs1257230167 897 dbSNP
rs928432244 899 dbSNP
rs958555629 900 dbSNP
rs991226845 902 dbSNP
rs1362992236 903 dbSNP
rs914361575 906 dbSNP
rs947011120 908 dbSNP
rs151009543 918 dbSNP
rs1224772010 919 dbSNP
rs1342050675 931 dbSNP
rs924836062 933 dbSNP
rs1414121147 935 dbSNP
rs933571232 936 dbSNP
rs1391847575 937 dbSNP
rs1395849693 942 dbSNP
rs207477001 943 dbSNP
rs1473859648 952 dbSNP
rs960977349 952 dbSNP
rs1369440234 955 dbSNP
rs1051997361 970 dbSNP
rs533110409 972 dbSNP
rs1183524127 973 dbSNP
rs551546620 979 dbSNP
rs775454130 980 dbSNP
rs1193750944 984 dbSNP
rs932767644 985 dbSNP
rs1273406150 988 dbSNP
rs1232496920 992 dbSNP
rs1335530650 1006 dbSNP
rs560278090 1008 dbSNP
rs527547112 1009 dbSNP
rs1332976069 1011 dbSNP
rs1407312594 1013 dbSNP
rs1391780702 1021 dbSNP
rs1164439822 1025 dbSNP
rs1213093791 1029 dbSNP
rs372349955 1031 dbSNP
rs1007722002 1032 dbSNP
rs1470039683 1033 dbSNP
rs891148501 1038 dbSNP
rs1459186423 1040 dbSNP
rs547272824 1050 dbSNP
rs1249817895 1053 dbSNP
rs1424112331 1059 dbSNP
rs567223009 1063 dbSNP
rs1253317285 1068 dbSNP
rs993875919 1070 dbSNP
rs1026331875 1072 dbSNP
rs971158938 1073 dbSNP
rs1269715194 1074 dbSNP
rs1224299196 1078 dbSNP
rs1474695324 1079 dbSNP
rs538168587 1080 dbSNP
rs994594236 1094 dbSNP
rs1401813126 1102 dbSNP
rs1325548542 1105 dbSNP
rs1027902040 1107 dbSNP
rs1391329694 1108 dbSNP
rs1296951667 1111 dbSNP
rs550402871 1112 dbSNP
rs1396413031 1113 dbSNP
rs1396913052 1114 dbSNP
rs1002393862 1115 dbSNP
rs1174828115 1115 dbSNP
rs571555919 1115 dbSNP
rs768757224 1115 dbSNP
rs1466827677 1124 dbSNP
rs1249683116 1130 dbSNP
rs1002775672 1132 dbSNP
rs1282149387 1141 dbSNP
rs1034675776 1146 dbSNP
rs1348702232 1169 dbSNP
rs530999643 1176 dbSNP
rs987820058 1176 dbSNP
rs1367683601 1185 dbSNP
rs1035639340 1186 dbSNP
rs958523011 1187 dbSNP
rs991331282 1198 dbSNP
rs1353750506 1199 dbSNP
rs142304914 1219 dbSNP
rs567480928 1224 dbSNP
rs1343796295 1229 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 126069.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gucuuaggaacgGACCCACg 5'
                      ||||||| 
Target 5' -----------gCUGGGUGc 3'
 		1 - 9
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000323169.5 | 3UTR | GCUGGGUGCAGUGGCUCAUGCCUGUAACCCC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
172 hsa-miR-500b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059905 HDGF heparin binding growth factor 2 4
MIRT235394 KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 2 4
MIRT442246 PYGO1 pygopus family PHD finger 1 2 2
MIRT443591 ZNF439 zinc finger protein 439 2 4
MIRT453280 EFTUD2 elongation factor Tu GTP binding domain containing 2 2 2
MIRT463540 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT465589 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT469462 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT485449 KCTD15 potassium channel tetramerization domain containing 15 2 4
MIRT486682 WDR81 WD repeat domain 81 2 2
MIRT489078 POLM DNA polymerase mu 2 2
MIRT493734 GREM2 gremlin 2, DAN family BMP antagonist 2 2
MIRT494872 DYNLL2 dynein light chain LC8-type 2 2 2
MIRT496130 RNF103-CHMP3 RNF103-CHMP3 readthrough 2 2
MIRT496489 CHMP3 charged multivesicular body protein 3 2 2
MIRT496924 CLMN calmin 2 2
MIRT497297 TMEM119 transmembrane protein 119 2 2
MIRT499103 AGRN agrin 2 2
MIRT508979 CXorf38 chromosome X open reading frame 38 2 2
MIRT509911 NIPAL1 NIPA like domain containing 1 2 2
MIRT512820 ARRDC2 arrestin domain containing 2 2 4
MIRT512827 KBTBD6 kelch repeat and BTB domain containing 6 2 4
MIRT515360 MRPL52 mitochondrial ribosomal protein L52 2 2
MIRT516610 TRIM58 tripartite motif containing 58 2 2
MIRT517053 TLDC1 TBC/LysM-associated domain containing 1 2 2
MIRT517637 ZNF491 zinc finger protein 491 2 2
MIRT518270 LEAP2 liver enriched antimicrobial peptide 2 2 2
MIRT518625 STAR steroidogenic acute regulatory protein 2 2
MIRT518887 N4BP2L2 NEDD4 binding protein 2 like 2 2 2
MIRT519026 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT520365 UBE2G2 ubiquitin conjugating enzyme E2 G2 2 2
MIRT521106 SLC1A5 solute carrier family 1 member 5 2 2
MIRT521943 PHC3 polyhomeotic homolog 3 2 2
MIRT522253 NPEPPS aminopeptidase puromycin sensitive 2 2
MIRT522853 KIAA1551 KIAA1551 2 2
MIRT522868 KIAA1549 KIAA1549 2 2
MIRT524207 DDX19B DEAD-box helicase 19B 2 2
MIRT526004 ARHGAP27 Rho GTPase activating protein 27 2 2
MIRT527769 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT527827 TMEM74B transmembrane protein 74B 2 2
MIRT527861 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT528040 WT1 Wilms tumor 1 2 2
MIRT529802 ZDHHC8 zinc finger DHHC-type containing 8 2 2
MIRT531723 TARS threonyl-tRNA synthetase 2 2
MIRT531996 BARD1 BRCA1 associated RING domain 1 2 2
MIRT533338 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT533621 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT533652 TMOD2 tropomodulin 2 2 2
MIRT534397 SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 2 2
MIRT538686 CCDC80 coiled-coil domain containing 80 2 2
MIRT540444 RBM43 RNA binding motif protein 43 2 2
MIRT542586 ZC3H12C zinc finger CCCH-type containing 12C 2 8
MIRT542796 PLEKHA3 pleckstrin homology domain containing A3 2 4
MIRT542991 ERC1 ELKS/RAB6-interacting/CAST family member 1 2 2
MIRT544424 ZNF460 zinc finger protein 460 2 4
MIRT545740 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 4
MIRT552618 ZBTB8A zinc finger and BTB domain containing 8A 2 2
MIRT554456 SAMD8 sterile alpha motif domain containing 8 2 2
MIRT569663 PRIM1 DNA primase subunit 1 2 2
MIRT569924 PCSK9 proprotein convertase subtilisin/kexin type 9 2 2
MIRT570140 IL1RL2 interleukin 1 receptor like 2 2 2
MIRT573558 TMEM120B transmembrane protein 120B 2 2
MIRT574282 OPRD1 opioid receptor delta 1 2 2
MIRT575335 Fbxo6 F-box protein 6 2 2
MIRT607057 IDS iduronate 2-sulfatase 2 2
MIRT607078 POM121L7 POM121 transmembrane nucleoporin like 7 pseudogene 2 2
MIRT607500 HEBP2 heme binding protein 2 2 2
MIRT607530 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT607808 RHBDL2 rhomboid like 2 2 2
MIRT608079 ZFP14 ZFP14 zinc finger protein 2 2
MIRT609119 NUDT3 nudix hydrolase 3 2 2
MIRT609745 PTCH1 patched 1 2 2
MIRT612904 HIF1AN hypoxia inducible factor 1 alpha subunit inhibitor 2 2
MIRT618720 PCSK2 proprotein convertase subtilisin/kexin type 2 2 2
MIRT618778 HLA-E major histocompatibility complex, class I, E 2 2
MIRT619015 SLC2A6 solute carrier family 2 member 6 2 2
MIRT623223 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT623819 GEMIN6 gem nuclear organelle associated protein 6 2 2
MIRT625704 OPTN optineurin 2 2
MIRT626437 CHDH choline dehydrogenase 2 2
MIRT628087 KAT7 lysine acetyltransferase 7 2 2
MIRT628936 APOB apolipoprotein B 2 2
MIRT633543 PGBD5 piggyBac transposable element derived 5 2 2
MIRT634348 SGOL1 shugoshin 1 2 2
MIRT634611 KIAA1919 major facilitator superfamily domain containing 4B 2 2
MIRT635243 QPRT quinolinate phosphoribosyltransferase 2 2
MIRT636681 BTLA B and T lymphocyte associated 2 2
MIRT636923 ZNF845 zinc finger protein 845 2 2
MIRT637606 ZNF554 zinc finger protein 554 2 2
MIRT639242 RANGAP1 Ran GTPase activating protein 1 2 2
MIRT640835 POLR3A RNA polymerase III subunit A 2 2
MIRT642098 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT643087 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643934 C17orf104 meiosis specific with coiled-coil domain 2 2
MIRT644353 FXN frataxin 2 2
MIRT645628 SF3A3 splicing factor 3a subunit 3 2 2
MIRT645754 FAM213A family with sequence similarity 213 member A 2 2
MIRT646329 MVB12B multivesicular body subunit 12B 2 2
MIRT646817 COX19 COX19, cytochrome c oxidase assembly factor 2 2
MIRT647019 ADCY2 adenylate cyclase 2 2 2
MIRT647621 IGSF9B immunoglobulin superfamily member 9B 2 2
MIRT648517 PIGG phosphatidylinositol glycan anchor biosynthesis class G 2 2
MIRT648871 ABCA6 ATP binding cassette subfamily A member 6 2 2
MIRT649620 ITPKC inositol-trisphosphate 3-kinase C 2 2
MIRT650062 CCDC134 coiled-coil domain containing 134 2 2
MIRT650734 TNFSF8 TNF superfamily member 8 2 2
MIRT652389 TMEM55A phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2 2
MIRT654352 RBM27 RNA binding motif protein 27 2 2
MIRT655796 NOVA2 NOVA alternative splicing regulator 2 2 2
MIRT657329 HNRNPK heterogeneous nuclear ribonucleoprotein K 2 2
MIRT657734 GOSR1 golgi SNAP receptor complex member 1 2 2
MIRT660613 ANO6 anoctamin 6 2 2
MIRT661243 ARL17B ADP ribosylation factor like GTPase 17B 2 2
MIRT662245 PGBD4 piggyBac transposable element derived 4 2 2
MIRT662921 MED18 mediator complex subunit 18 2 2
MIRT662963 JPH2 junctophilin 2 2 2
MIRT663347 ZNF74 zinc finger protein 74 2 2
MIRT663528 MASTL microtubule associated serine/threonine kinase like 2 2
MIRT663547 CCR6 C-C motif chemokine receptor 6 2 2
MIRT663977 ZNF786 zinc finger protein 786 2 2
MIRT664084 METTL2B methyltransferase like 2B 2 2
MIRT664358 C16orf45 chromosome 16 open reading frame 45 2 2
MIRT664421 TIGD6 tigger transposable element derived 6 2 2
MIRT664476 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT664979 TDRD1 tudor domain containing 1 2 2
MIRT665128 PYCRL pyrroline-5-carboxylate reductase 3 2 2
MIRT666259 SLC31A1 solute carrier family 31 member 1 2 2
MIRT666321 SLC16A10 solute carrier family 16 member 10 2 2
MIRT666881 POLQ DNA polymerase theta 2 2
MIRT668469 FADS6 fatty acid desaturase 6 2 2
MIRT669554 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT669835 ISCA2 iron-sulfur cluster assembly 2 2 2
MIRT670185 CCDC142 coiled-coil domain containing 142 2 2
MIRT672020 PXMP4 peroxisomal membrane protein 4 2 2
MIRT672070 KIAA0930 KIAA0930 2 2
MIRT672475 RTTN rotatin 2 2
MIRT672851 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT673090 AK1 adenylate kinase 1 2 2
MIRT673581 KDELC2 KDEL motif containing 2 2 2
MIRT674586 SLC35B4 solute carrier family 35 member B4 2 2
MIRT675001 STRN3 striatin 3 2 2
MIRT679018 MTMR10 myotubularin related protein 10 2 2
MIRT679680 STAT3 signal transducer and activator of transcription 3 2 2
MIRT682833 FLG2 filaggrin family member 2 2 2
MIRT682886 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT683442 AP3B2 adaptor related protein complex 3 beta 2 subunit 2 2
MIRT687040 RNF115 ring finger protein 115 2 2
MIRT691957 RHOH ras homolog family member H 2 2
MIRT694625 ZFPM1 zinc finger protein, FOG family member 1 2 2
MIRT695637 SLC26A2 solute carrier family 26 member 2 2 2
MIRT697640 WRN Werner syndrome RecQ like helicase 2 2
MIRT702009 MIDN midnolin 2 2
MIRT702034 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT704789 CDK6 cyclin dependent kinase 6 2 2
MIRT705728 AMMECR1L AMMECR1 like 2 2
MIRT705879 ADM adrenomedullin 2 2
MIRT706220 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT708418 CERS4 ceramide synthase 4 2 2
MIRT709114 C3orf18 chromosome 3 open reading frame 18 2 2
MIRT709595 ITPA inosine triphosphatase 2 2
MIRT710945 MRPL45 mitochondrial ribosomal protein L45 2 2
MIRT712345 NLN neurolysin 2 2
MIRT712530 CYTH2 cytohesin 2 2 2
MIRT714019 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT717287 ARMC12 armadillo repeat containing 12 2 2
MIRT717733 FGF1 fibroblast growth factor 1 2 2
MIRT718083 CLIC5 chloride intracellular channel 5 2 2
MIRT718562 MUC20 mucin 20, cell surface associated 2 2
MIRT721639 MYLK3 myosin light chain kinase 3 2 2
MIRT722632 C8A complement C8 alpha chain 2 2
MIRT723177 CDCA4 cell division cycle associated 4 2 2
MIRT725523 FAM229B family with sequence similarity 229 member B 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-500b Methotrexate 126941 NSC740 approved resistant cell line (W1)
hsa-miR-500b-3p Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (AsPC-1)
hsa-miR-500b-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-500b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-500b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-500b-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)
hsa-miR-500b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)

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