miRTarBase - #MIRT518984


—
pre-miRNA Information
pre-miRNA hsa-mir-6830   
Genomic Coordinates chr5: 132217849 - 132217918
Description Homo sapiens miR-6830 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6830-3p
Sequence 48| UGUCUUUCUUCUCUCCCUUGCAG |70
Evidence Experimental
Experiments Meta-analysis
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs772425565 6 dbSNP
rs1223446041 11 dbSNP
rs771777520 13 dbSNP
rs1416751362 14 dbSNP
rs564286593 15 dbSNP
rs748409873 17 dbSNP
rs1297884779 20 dbSNP
Putative Targets

Gene Information
Gene Symbol NNT   
Synonyms GCCD4
Description nicotinamide nucleotide transhydrogenase
Transcript NM_012343   
Other Transcripts NM_182977   
Expression
Putative miRNA Targets on NNT
3'UTR of NNT
(miRNA target sites are highlighted)		 
>NNT|NM_012343|3'UTR
   1 ATATTAAGGATCAAGCTGTTAGCTAATAATGCCACCTCTGCAGTTTTGGGAACAGGCAAATAAAGTATCAGTATACATGG
  81 TGATGTACATCTGTAGCAAAGCTCTTGGAGAAAATGAAGACTGAAGAAAGCAAAGCAAAAACTGTATAGAGAGATTTTTC
 161 AAAAGCAGTAATCCCTCAATTTTAAAAAAGGATTGAAAATTCTAAATGTCTTTCTGTGCATATTTTTTGTGTTAGGAATC
 241 AAAAGTATTTTATAAAAGGAGAAAGAACAGCCTCATTTTAGATGTAGTCCTGTTGGATTTTTTATGCCTCCTCAGTAACC
 321 AGAAATGTTTTAAAAAACTAAGTGTTTAGGATTTCAAGACAACATTATACATGGCTCTGAAATATCTGACACAATGTAAA
 401 CATTGCAGGCACCTGCATTTTATGTTTTTTTTTTCAACAAATGTGACTAATTTGAAACTTTTATGAACTTCTGAGCTGTC
 481 CCCTTGCAATTCAACCGCAGTTTGAATTAATCATATCAAATCAGTTTTAATTTTTTAAATTGTACTTCAGAGTCTATATT
 561 TCAAGGGCACATTTTCTCACTACTATTTTAATACATTAAAGGACTAAATAATCTTTCAGAGATGCTGGAAACAAATCATT
 641 TGCTTTATATGTTTCATTAGAATACCAATGAAACATACAACTTGAAAATTAGTAATAGTATTTTTGAAGATCCCATTTCT
 721 AATTGGAGATCTCTTTAATTTCGATCAACTTATAATGTGTAGTACTATATTAAGTGCACTTGAGTGGAATTCAACATTTG
 801 ACTAATAAAATGAGTTCATCATGTTGGCAAGTGATGTGGCAATTATCTCTGGTGACAAAAGAGTAAAATCAAATATTTCT
 881 GCCTGTTACAAATATCAAGGAAGACCTGCTACTATGAAATAGATGACATTAATCTGTCTTCACTGTTTATAATACGGATG
 961 GATTTTTTTTCAAATCAGTGTGTGTTTTGAGGTCTTATGTAATTGATGACATTTGAGAGAAATGGTGGCTTTTTTTAGCT
1041 ACCTCTTTGTTCATTTAAGCACCAGTAAAGATCATGTCTTTTTATAGAAGTGTAGATTTTCTTTGTGACTTTGCTATCGT
1121 GCCTAAAGCTCTAAATATAGGTGAATGTGTGATGAATACTCAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gacguucccUCUCUUCUUUCUgu 5'
                   | ||:|||||||  
Target 5' tattttataAAAGGAGAAAGAac 3'
 246 - 268 138.00 -11.20
2 
miRNA  3' gacguucccucucUUCUUUCUGu 5'
                       |||:||||| 
Target 5' tgttacaaatatcAAGGAAGACc 3'
 884 - 906 134.00 -8.20
3 
miRNA  3' gacgUUCCCUCU--CUUCUUUCugu 5'
              || | |||  ||||||||   
Target 5' agaaAATGAAGACTGAAGAAAGcaa 3'
 109 - 133 129.00 -10.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM240903 1 COSMIC
COSN31502248 7 COSMIC
COSN30497304 13 COSMIC
COSN5076842 26 COSMIC
COSN30535149 68 COSMIC
COSN31509711 70 COSMIC
COSN30191290 88 COSMIC
COSN31502465 167 COSMIC
COSN20101203 190 COSMIC
COSN20101204 435 COSMIC
COSN20566433 506 COSMIC
COSN15734450 559 COSMIC
COSN29618111 618 COSMIC
COSN8631079 1004 COSMIC
COSN14616786 1091 COSMIC
COSN15343447 1286 COSMIC
COSN23106773 1387 COSMIC
COSN25088279 1428 COSMIC
COSN9447607 1527 COSMIC
COSN23228947 1715 COSMIC
COSN27995977 1988 COSMIC
COSN27304089 2074 COSMIC
COSN16501844 2176 COSMIC
COSN17226150 2269 COSMIC
COSN7942993 2331 COSMIC
COSN19552123 2356 COSMIC
COSN28505059 2483 COSMIC
COSN27755851 2848 COSMIC
COSN2107110 2893 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs922340043 5 dbSNP
rs1278045307 10 dbSNP
rs945738367 16 dbSNP
rs1216350199 17 dbSNP
rs750730374 19 dbSNP
rs756238212 23 dbSNP
rs191475277 28 dbSNP
rs754329623 30 dbSNP
rs1269410935 31 dbSNP
rs1163048024 35 dbSNP
rs755463308 36 dbSNP
rs55984047 37 dbSNP
rs925578528 43 dbSNP
rs16873502 51 dbSNP
rs1056099615 56 dbSNP
rs147932866 58 dbSNP
rs1225304813 60 dbSNP
rs1357969918 63 dbSNP
rs1288920472 64 dbSNP
rs1244671407 66 dbSNP
rs1317128931 69 dbSNP
rs894431719 71 dbSNP
rs1221722203 76 dbSNP
rs534489214 78 dbSNP
rs1476458045 82 dbSNP
rs1054833510 84 dbSNP
rs1363686799 85 dbSNP
rs184272260 86 dbSNP
rs948794691 89 dbSNP
rs897667100 92 dbSNP
rs1157116177 93 dbSNP
rs1008185384 104 dbSNP
rs1418742046 117 dbSNP
rs1044522730 136 dbSNP
rs1339122870 142 dbSNP
rs907307577 145 dbSNP
rs1019612724 148 dbSNP
rs1268874974 148 dbSNP
rs1333144780 149 dbSNP
rs1027753514 155 dbSNP
rs1261990766 156 dbSNP
rs371409962 161 dbSNP
rs777029045 165 dbSNP
rs538347397 166 dbSNP
rs1283657135 167 dbSNP
rs1225174067 179 dbSNP
rs34053391 184 dbSNP
rs1056248207 193 dbSNP
rs886998545 195 dbSNP
rs558187103 209 dbSNP
rs187591100 217 dbSNP
rs113832882 221 dbSNP
rs1407177291 223 dbSNP
rs34304579 223 dbSNP
rs1016993800 230 dbSNP
rs962447762 232 dbSNP
rs996992904 234 dbSNP
rs1021109684 236 dbSNP
rs1028038942 239 dbSNP
rs1430834954 241 dbSNP
rs1262759896 246 dbSNP
rs1202902062 256 dbSNP
rs1464148520 258 dbSNP
rs1448813717 260 dbSNP
rs955110685 263 dbSNP
rs1191606833 265 dbSNP
rs1380005595 269 dbSNP
rs1321078740 273 dbSNP
rs1263031790 276 dbSNP
rs1228013244 280 dbSNP
rs1328171801 283 dbSNP
rs1293496408 284 dbSNP
rs986942421 294 dbSNP
rs1383794136 295 dbSNP
rs1338872730 297 dbSNP
rs924785805 305 dbSNP
rs1405752193 311 dbSNP
rs1178986143 315 dbSNP
rs1168889254 323 dbSNP
rs1376253083 332 dbSNP
rs977154098 338 dbSNP
rs925746350 339 dbSNP
rs745989161 341 dbSNP
rs956261921 343 dbSNP
rs1448279492 356 dbSNP
rs935663440 361 dbSNP
rs991204921 363 dbSNP
rs1184998443 369 dbSNP
rs1171627324 373 dbSNP
rs1255177142 376 dbSNP
rs1196210174 390 dbSNP
rs1341372225 396 dbSNP
rs915568418 410 dbSNP
rs73753606 411 dbSNP
rs914552447 420 dbSNP
rs1045642830 425 dbSNP
rs138980708 425 dbSNP
rs796540619 425 dbSNP
rs1340145074 426 dbSNP
rs111607585 427 dbSNP
rs770327974 428 dbSNP
rs1394785480 435 dbSNP
rs1339708449 441 dbSNP
rs1167783098 442 dbSNP
rs1425868852 458 dbSNP
rs1405447817 460 dbSNP
rs1385269456 462 dbSNP
rs796462613 464 dbSNP
rs574685772 465 dbSNP
rs540520330 469 dbSNP
rs1007966393 497 dbSNP
rs141702531 498 dbSNP
rs184650537 500 dbSNP
rs886967328 523 dbSNP
rs1294008090 528 dbSNP
rs1243941582 529 dbSNP
rs1355900594 537 dbSNP
rs72760484 538 dbSNP
rs1285441269 557 dbSNP
rs1241463430 577 dbSNP
rs546335560 583 dbSNP
rs1334299334 586 dbSNP
rs1038325107 591 dbSNP
rs368502379 596 dbSNP
rs1368059165 600 dbSNP
rs1304417628 601 dbSNP
rs1403165755 605 dbSNP
rs1412452390 612 dbSNP
rs1021243967 621 dbSNP
rs1470973113 623 dbSNP
rs1361811667 629 dbSNP
rs1181241049 637 dbSNP
rs1265953367 640 dbSNP
rs1480712790 650 dbSNP
rs1271042677 651 dbSNP
rs143831033 652 dbSNP
rs1183001907 656 dbSNP
rs1220162371 669 dbSNP
rs372923830 671 dbSNP
rs1451047493 675 dbSNP
rs1363967283 680 dbSNP
rs751693152 687 dbSNP
rs547287174 688 dbSNP
rs1348861254 690 dbSNP
rs996486777 698 dbSNP
rs1224571947 699 dbSNP
rs966846776 702 dbSNP
rs531818374 711 dbSNP
rs1281860091 716 dbSNP
rs1436410357 725 dbSNP
rs1359324110 731 dbSNP
rs1001072858 732 dbSNP
rs1402058516 734 dbSNP
rs1424805920 739 dbSNP
rs1028424046 743 dbSNP
rs1480600537 744 dbSNP
rs1365415851 755 dbSNP
rs190318810 758 dbSNP
rs116409496 766 dbSNP
rs971052559 776 dbSNP
rs768906780 788 dbSNP
rs1238208509 794 dbSNP
rs1204550443 795 dbSNP
rs562571421 797 dbSNP
rs181406943 803 dbSNP
rs1360241798 804 dbSNP
rs1223955674 805 dbSNP
rs1264142172 808 dbSNP
rs1488452961 814 dbSNP
rs1031824317 821 dbSNP
rs1363326284 836 dbSNP
rs1270251246 838 dbSNP
rs151107527 840 dbSNP
rs760421909 845 dbSNP
rs1196706064 851 dbSNP
rs1432359179 857 dbSNP
rs990798324 862 dbSNP
rs1240379748 877 dbSNP
rs1319398540 882 dbSNP
rs377326235 889 dbSNP
rs566138928 890 dbSNP
rs1021840802 897 dbSNP
rs970737217 925 dbSNP
rs1176377341 937 dbSNP
rs1379369038 940 dbSNP
rs1048923167 942 dbSNP
rs980099074 949 dbSNP
rs1169721064 950 dbSNP
rs1447663487 952 dbSNP
rs928669823 956 dbSNP
rs943430028 957 dbSNP
rs1241655396 963 dbSNP
rs202207795 963 dbSNP
rs1209921383 965 dbSNP
rs1308591549 966 dbSNP
rs768190254 977 dbSNP
rs1457376191 978 dbSNP
rs1298721585 979 dbSNP
rs1452872956 998 dbSNP
rs1384604946 1000 dbSNP
rs184732363 1004 dbSNP
rs1444376366 1012 dbSNP
rs766180637 1014 dbSNP
rs189141866 1019 dbSNP
rs1172375071 1023 dbSNP
rs1308798601 1024 dbSNP
rs1383817689 1027 dbSNP
rs14491 1030 dbSNP
rs901830628 1030 dbSNP
rs983540716 1036 dbSNP
rs908375322 1037 dbSNP
rs1310700223 1038 dbSNP
rs1411975325 1042 dbSNP
rs750954766 1044 dbSNP
rs776246599 1046 dbSNP
rs997538497 1056 dbSNP
rs1038613433 1064 dbSNP
rs898389247 1065 dbSNP
rs1202983967 1067 dbSNP
rs1042657946 1073 dbSNP
rs932572547 1092 dbSNP
rs1049409430 1094 dbSNP
rs568648829 1096 dbSNP
rs537939919 1103 dbSNP
rs1228762258 1108 dbSNP
rs890817847 1119 dbSNP
rs1007976575 1120 dbSNP
rs1456711013 1122 dbSNP
rs1373729657 1125 dbSNP
rs1031456791 1126 dbSNP
rs1299699808 1129 dbSNP
rs1198411949 1130 dbSNP
rs1032471064 1139 dbSNP
rs891544513 1141 dbSNP
rs554516664 1148 dbSNP
rs1164280990 1149 dbSNP
rs1012640047 1150 dbSNP
rs1011724622 1160 dbSNP
rs1022699473 1174 dbSNP
rs1180529692 1180 dbSNP
rs113936896 1182 dbSNP
rs970323680 1188 dbSNP
rs981114928 1189 dbSNP
rs1489142251 1196 dbSNP
rs980785902 1197 dbSNP
rs112625662 1212 dbSNP
rs1483388425 1227 dbSNP
rs533854658 1230 dbSNP
rs1317187401 1231 dbSNP
rs1183058964 1233 dbSNP
rs1410955171 1243 dbSNP
rs1308855199 1245 dbSNP
rs950603747 1247 dbSNP
rs1349797312 1251 dbSNP
rs1283779586 1252 dbSNP
rs1422782262 1254 dbSNP
rs186242454 1258 dbSNP
rs985118071 1265 dbSNP
rs1171286929 1269 dbSNP
rs1035652394 1281 dbSNP
rs1425772541 1283 dbSNP
rs190725045 1284 dbSNP
rs546247932 1285 dbSNP
rs716960 1286 dbSNP
rs569254928 1306 dbSNP
rs1202164842 1313 dbSNP
rs1431979383 1327 dbSNP
rs974834692 1336 dbSNP
rs1264618564 1362 dbSNP
rs1485984751 1362 dbSNP
rs1269706789 1366 dbSNP
rs200317908 1366 dbSNP
rs1318719390 1368 dbSNP
rs1434676407 1368 dbSNP
rs181517819 1368 dbSNP
rs70997432 1368 dbSNP
rs1407251401 1370 dbSNP
rs138029232 1376 dbSNP
rs923387764 1377 dbSNP
rs1464966396 1384 dbSNP
rs1377618041 1385 dbSNP
rs1428527483 1387 dbSNP
rs963814101 1387 dbSNP
rs397811308 1388 dbSNP
rs973903171 1389 dbSNP
rs1448477549 1390 dbSNP
rs919782806 1398 dbSNP
rs1412012677 1400 dbSNP
rs796364031 1412 dbSNP
rs1042377469 1414 dbSNP
rs933299980 1414 dbSNP
rs1280570087 1420 dbSNP
rs1383736092 1430 dbSNP
rs1339116599 1436 dbSNP
rs902518088 1438 dbSNP
rs936914025 1440 dbSNP
rs1299299172 1444 dbSNP
rs1463955363 1458 dbSNP
rs1264179002 1460 dbSNP
rs1166122884 1469 dbSNP
rs576649903 1470 dbSNP
rs1385402134 1472 dbSNP
rs895304074 1479 dbSNP
rs1440545691 1490 dbSNP
rs1255189474 1492 dbSNP
rs1211773377 1494 dbSNP
rs1235439736 1501 dbSNP
rs186241226 1505 dbSNP
rs1022667070 1509 dbSNP
rs1227682875 1518 dbSNP
rs1360439986 1524 dbSNP
rs1286239060 1528 dbSNP
rs1242861548 1532 dbSNP
rs943650011 1539 dbSNP
rs10069201 1545 dbSNP
rs1308112638 1552 dbSNP
rs1476817864 1560 dbSNP
rs1369188982 1566 dbSNP
rs1002588339 1569 dbSNP
rs141085785 1573 dbSNP
rs1169923255 1575 dbSNP
rs1425578312 1583 dbSNP
rs1428623934 1588 dbSNP
rs891517855 1596 dbSNP
rs1025898200 1597 dbSNP
rs1471587929 1600 dbSNP
rs1011772262 1609 dbSNP
rs1043214033 1612 dbSNP
rs1174212131 1616 dbSNP
rs950455474 1629 dbSNP
rs150309124 1630 dbSNP
rs1473538862 1638 dbSNP
rs137878316 1640 dbSNP
rs1001735752 1652 dbSNP
rs964571277 1653 dbSNP
rs1490549805 1657 dbSNP
rs1339044076 1677 dbSNP
rs541374820 1683 dbSNP
rs556122133 1683 dbSNP
rs1035869548 1685 dbSNP
rs1292081334 1715 dbSNP
rs564408837 1716 dbSNP
rs1208323495 1722 dbSNP
rs1355850203 1730 dbSNP
rs975014237 1731 dbSNP
rs1230550186 1735 dbSNP
rs960284123 1744 dbSNP
rs533432865 1751 dbSNP
rs1288335224 1759 dbSNP
rs923106654 1769 dbSNP
rs933352457 1772 dbSNP
rs1370166778 1774 dbSNP
rs1014891447 1776 dbSNP
rs1324907943 1786 dbSNP
rs1403266789 1791 dbSNP
rs963480981 1808 dbSNP
rs1275985075 1815 dbSNP
rs1159634143 1825 dbSNP
rs978189000 1827 dbSNP
rs973918660 1828 dbSNP
rs1181423429 1840 dbSNP
rs1480702625 1844 dbSNP
rs34289650 1849 dbSNP
rs1196780007 1850 dbSNP
rs1451259815 1851 dbSNP
rs954046858 1861 dbSNP
rs142465518 1865 dbSNP
rs1287497877 1871 dbSNP
rs985296925 1873 dbSNP
rs531311946 1875 dbSNP
rs1487050199 1895 dbSNP
rs936697257 1897 dbSNP
rs912442275 1898 dbSNP
rs1267862181 1922 dbSNP
rs943951304 1932 dbSNP
rs190700755 1935 dbSNP
rs912282013 1935 dbSNP
rs948240691 1935 dbSNP
rs144632030 1936 dbSNP
rs1436796356 1944 dbSNP
rs1386229255 1954 dbSNP
rs1002557034 1970 dbSNP
rs1414988198 1971 dbSNP
rs1189260766 1973 dbSNP
rs1427100028 1973 dbSNP
rs1170739593 1977 dbSNP
rs1026047339 1979 dbSNP
rs1242755703 1989 dbSNP
rs35429460 1999 dbSNP
rs1463681109 2000 dbSNP
rs1420576389 2009 dbSNP
rs947156533 2012 dbSNP
rs554487506 2020 dbSNP
rs1277199884 2025 dbSNP
rs1219141254 2029 dbSNP
rs1043232773 2030 dbSNP
rs905620194 2037 dbSNP
rs182894790 2046 dbSNP
rs1230194820 2047 dbSNP
rs1362514884 2050 dbSNP
rs746565356 2051 dbSNP
rs574967807 2053 dbSNP
rs1359602026 2062 dbSNP
rs1448572761 2062 dbSNP
rs974660159 2062 dbSNP
rs1352130089 2070 dbSNP
rs62368580 2076 dbSNP
rs1030144815 2077 dbSNP
rs954540069 2098 dbSNP
rs1389710173 2109 dbSNP
rs1057248518 2123 dbSNP
rs1484474756 2127 dbSNP
rs1374556599 2129 dbSNP
rs896043195 2131 dbSNP
rs116460111 2133 dbSNP
rs1274755465 2175 dbSNP
rs1206599911 2179 dbSNP
rs1311072440 2179 dbSNP
rs138690778 2183 dbSNP
rs1014908013 2185 dbSNP
rs963746664 2186 dbSNP
rs539734075 2201 dbSNP
rs1381128156 2202 dbSNP
rs1282172726 2218 dbSNP
rs1447230018 2221 dbSNP
rs943790203 2222 dbSNP
rs1309941805 2223 dbSNP
rs989922099 2227 dbSNP
rs994922075 2231 dbSNP
rs1245884518 2232 dbSNP
rs535252358 2233 dbSNP
rs1029455819 2235 dbSNP
rs1165806997 2240 dbSNP
rs1180734847 2245 dbSNP
rs953442930 2248 dbSNP
rs1425746535 2250 dbSNP
rs985264260 2254 dbSNP
rs770323169 2255 dbSNP
rs991059468 2256 dbSNP
rs535618147 2260 dbSNP
rs930166943 2263 dbSNP
rs1047465813 2265 dbSNP
rs1481816115 2268 dbSNP
rs965272324 2269 dbSNP
rs988768892 2271 dbSNP
rs912890742 2281 dbSNP
rs947009588 2282 dbSNP
rs978453382 2289 dbSNP
rs1350878579 2290 dbSNP
rs886219341 2300 dbSNP
rs576338824 2303 dbSNP
rs1294144419 2311 dbSNP
rs1459658318 2317 dbSNP
rs1404062264 2318 dbSNP
rs927012138 2328 dbSNP
rs545501986 2331 dbSNP
rs879873788 2332 dbSNP
rs1323535305 2337 dbSNP
rs1458152625 2339 dbSNP
rs1414625543 2340 dbSNP
rs1057215333 2341 dbSNP
rs1180699720 2351 dbSNP
rs1472528876 2355 dbSNP
rs1454708141 2356 dbSNP
rs1249237427 2361 dbSNP
rs1401463483 2366 dbSNP
rs1191213890 2369 dbSNP
rs1489260099 2370 dbSNP
rs375050183 2371 dbSNP
rs1005974583 2379 dbSNP
rs896010658 2395 dbSNP
rs541965021 2402 dbSNP
rs1037053562 2405 dbSNP
rs1329667304 2406 dbSNP
rs149288188 2408 dbSNP
rs995205017 2425 dbSNP
rs1029011000 2428 dbSNP
rs1237642410 2438 dbSNP
rs1284307072 2449 dbSNP
rs1302084744 2452 dbSNP
rs1357900969 2454 dbSNP
rs889193512 2458 dbSNP
rs1226517628 2460 dbSNP
rs1293211687 2468 dbSNP
rs1436052473 2477 dbSNP
rs1391329588 2478 dbSNP
rs368384741 2483 dbSNP
rs1019458211 2484 dbSNP
rs1378651636 2486 dbSNP
rs1434456758 2491 dbSNP
rs1422416898 2497 dbSNP
rs965242552 2499 dbSNP
rs554065251 2509 dbSNP
rs1200311133 2517 dbSNP
rs1020583394 2526 dbSNP
rs372619819 2530 dbSNP
rs1206523238 2534 dbSNP
rs202239317 2535 dbSNP
rs572355467 2537 dbSNP
rs968683154 2549 dbSNP
rs978804878 2554 dbSNP
rs1229459230 2555 dbSNP
rs1302715540 2558 dbSNP
rs926989622 2559 dbSNP
rs1318968468 2563 dbSNP
rs1434913377 2571 dbSNP
rs1403340810 2572 dbSNP
rs1188555036 2573 dbSNP
rs1370244178 2574 dbSNP
rs1471884547 2585 dbSNP
rs1391560445 2588 dbSNP
rs937073568 2593 dbSNP
rs1163183444 2611 dbSNP
rs1256562066 2612 dbSNP
rs1272100746 2614 dbSNP
rs1424971300 2615 dbSNP
rs1467454369 2622 dbSNP
rs1169009463 2623 dbSNP
rs1397621250 2626 dbSNP
rs1344400623 2631 dbSNP
rs1390433432 2633 dbSNP
rs1334461070 2644 dbSNP
rs1226940269 2651 dbSNP
rs992576590 2653 dbSNP
rs1341732619 2656 dbSNP
rs572572728 2657 dbSNP
rs1292529834 2661 dbSNP
rs546080096 2662 dbSNP
rs1402046464 2663 dbSNP
rs1220189603 2670 dbSNP
rs940826694 2680 dbSNP
rs1036533030 2681 dbSNP
rs1255955202 2682 dbSNP
rs899387731 2683 dbSNP
rs954510662 2685 dbSNP
rs1201233547 2692 dbSNP
rs1368855922 2694 dbSNP
rs999398639 2701 dbSNP
rs541253228 2703 dbSNP
rs958330566 2706 dbSNP
rs187918518 2707 dbSNP
rs533494108 2708 dbSNP
rs1272534080 2713 dbSNP
rs916546539 2713 dbSNP
rs1186946496 2715 dbSNP
rs1264462584 2716 dbSNP
rs1267615630 2717 dbSNP
rs1289583109 2717 dbSNP
rs397997610 2717 dbSNP
rs564776546 2717 dbSNP
rs70997433 2717 dbSNP
rs889162510 2718 dbSNP
rs1008980763 2722 dbSNP
rs1351834963 2722 dbSNP
rs1019005703 2724 dbSNP
rs1164633688 2724 dbSNP
rs1456251670 2730 dbSNP
rs892557002 2736 dbSNP
rs1169209808 2742 dbSNP
rs1159869404 2746 dbSNP
rs1473508581 2751 dbSNP
rs928257794 2754 dbSNP
rs543664621 2757 dbSNP
rs1466932107 2761 dbSNP
rs1047637756 2774 dbSNP
rs1452409076 2775 dbSNP
rs562156247 2785 dbSNP
rs910052633 2787 dbSNP
rs576750568 2791 dbSNP
rs191223856 2792 dbSNP
rs1230801147 2795 dbSNP
rs1412211304 2795 dbSNP
rs1327630968 2799 dbSNP
rs1277270546 2802 dbSNP
rs1440927520 2810 dbSNP
rs1037468721 2811 dbSNP
rs1020130624 2818 dbSNP
rs553315800 2824 dbSNP
rs1438218288 2828 dbSNP
rs1393496192 2831 dbSNP
rs1320922200 2847 dbSNP
rs752584791 2848 dbSNP
rs1409574201 2852 dbSNP
rs900153454 2859 dbSNP
rs1379417712 2865 dbSNP
rs1197066900 2881 dbSNP
rs1341009530 2883 dbSNP
rs969025501 2884 dbSNP
rs1249053672 2885 dbSNP
rs1245633299 2898 dbSNP
rs375405207 2907 dbSNP
rs1401741945 2908 dbSNP
rs1284251718 2910 dbSNP
rs1220293207 2938 dbSNP
rs1000140021 2942 dbSNP
rs1345157735 2961 dbSNP
rs1276289701 2968 dbSNP
rs1231652548 2969 dbSNP
rs995866055 2973 dbSNP
rs1298061658 2978 dbSNP
rs1033974022 2980 dbSNP
rs958398983 2981 dbSNP
rs568177629 2982 dbSNP
rs1317608100 2984 dbSNP
rs1414933779 2987 dbSNP
rs916955575 2987 dbSNP
rs1404474833 2990 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23530.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23530.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760632. RNA binding protein: AGO2. Condition:AGO-CLIP-22RV1_C ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000264663.5 | 3UTR | CCAAAGGAUUAUAAAUCAUGCUGCUAUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000264663.5 | 3UTR | AUACCCAAAGGAUUAUAAAUCAUGCUGCUAUAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
82 hsa-miR-6830-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT081461 SSBP4 single stranded DNA binding protein 4 2 2
MIRT132029 IER5 immediate early response 5 2 2
MIRT187279 DAZAP2 DAZ associated protein 2 2 6
MIRT350303 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT350307 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT372105 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT408159 DCK deoxycytidine kinase 2 4
MIRT442623 LOX lysyl oxidase 2 2
MIRT442952 ASXL2 additional sex combs like 2, transcriptional regulator 2 2
MIRT469401 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT476631 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT485039 TMEM189 transmembrane protein 189 2 8
MIRT485133 RASSF8 Ras association domain family member 8 2 6
MIRT498963 ORC4 origin recognition complex subunit 4 2 8
MIRT500082 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT503018 CAND1 cullin associated and neddylation dissociated 1 2 2
MIRT503374 SCAMP1 secretory carrier membrane protein 1 2 2
MIRT504975 ZNF711 zinc finger protein 711 2 2
MIRT518984 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT520754 TFDP1 transcription factor Dp-1 2 6
MIRT526785 SGCD sarcoglycan delta 2 2
MIRT533868 TBL1XR1 transducin beta like 1 X-linked receptor 1 2 2
MIRT535107 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT538991 BAG4 BCL2 associated athanogene 4 2 2
MIRT543518 PRSS21 protease, serine 21 2 2
MIRT543813 SNX10 sorting nexin 10 2 2
MIRT543825 GSG1 germ cell associated 1 2 2
MIRT545334 CCDC83 coiled-coil domain containing 83 2 2
MIRT545669 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT547798 KAT7 lysine acetyltransferase 7 2 2
MIRT548068 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT549577 ZNF850 zinc finger protein 850 2 2
MIRT550753 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT550808 FAM229B family with sequence similarity 229 member B 2 2
MIRT551457 CARKD NAD(P)HX dehydratase 2 2
MIRT551852 RPS3 ribosomal protein S3 2 2
MIRT554218 SLC30A1 solute carrier family 30 member 1 2 2
MIRT556588 LEPROT leptin receptor overlapping transcript 2 2
MIRT557344 HDGF heparin binding growth factor 2 4
MIRT571945 LARP1 La ribonucleoprotein domain family member 1 2 2
MIRT574374 YY1 YY1 transcription factor 2 2
MIRT611142 CRISP1 cysteine rich secretory protein 1 2 4
MIRT611799 FCRL4 Fc receptor like 4 2 2
MIRT612834 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT617257 GLIPR1L2 GLI pathogenesis related 1 like 2 2 2
MIRT619781 NRIP2 nuclear receptor interacting protein 2 2 2
MIRT620440 SEMA3E semaphorin 3E 2 2
MIRT621725 TNR tenascin R 2 2
MIRT622905 PCDH17 protocadherin 17 2 2
MIRT623428 KLF6 Kruppel like factor 6 2 2
MIRT627856 PITPNM3 PITPNM family member 3 2 2
MIRT633894 FGF10 fibroblast growth factor 10 2 2
MIRT636257 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT640654 FRY FRY microtubule binding protein 2 2
MIRT640857 TSHZ2 teashirt zinc finger homeobox 2 2 4
MIRT641220 LRCH1 leucine rich repeats and calponin homology domain containing 1 2 2
MIRT642526 ANKRD9 ankyrin repeat domain 9 2 2
MIRT646011 TNFAIP8L2 TNF alpha induced protein 8 like 2 2 2
MIRT653317 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT657940 GATM glycine amidinotransferase 2 2
MIRT658291 FAM83F family with sequence similarity 83 member F 2 2
MIRT660607 ANTXR2 anthrax toxin receptor 2 2 2
MIRT664675 LMBR1L limb development membrane protein 1 like 2 2
MIRT664889 PRRG4 proline rich and Gla domain 4 2 2
MIRT666972 PHF20L1 PHD finger protein 20 like 1 2 2
MIRT669128 CD200 CD200 molecule 2 2
MIRT673267 RUNDC1 RUN domain containing 1 2 2
MIRT704609 CLN8 CLN8, transmembrane ER and ERGIC protein 2 2
MIRT709404 TADA2A transcriptional adaptor 2A 2 2
MIRT710963 CMKLR1 chemerin chemokine-like receptor 1 2 2
MIRT711745 DTX1 deltex E3 ubiquitin ligase 1 2 2
MIRT715009 CYP1B1 cytochrome P450 family 1 subfamily B member 1 2 2
MIRT715467 NEGR1 neuronal growth regulator 1 2 2
MIRT715737 CD226 CD226 molecule 2 2
MIRT716526 KSR2 kinase suppressor of ras 2 2 2
MIRT718311 TMPRSS11B transmembrane protease, serine 11B 2 2
MIRT719006 TMEM184C transmembrane protein 184C 2 2
MIRT719319 STAC SH3 and cysteine rich domain 2 2
MIRT722092 SUSD1 sushi domain containing 1 2 2
MIRT723198 TNRC6C trinucleotide repeat containing 6C 2 2
MIRT723239 BTLA B and T lymphocyte associated 2 2
MIRT724850 IGFBP5 insulin like growth factor binding protein 5 2 2

Error report submission