miRTarBase - #MIRT522772


—
pre-miRNA Information
pre-miRNA hsa-mir-3152   
Genomic Coordinates chr9: 18573306 - 18573379
Description Homo sapiens miR-3152 stem-loop
Comment Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method .
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3152-3p
Sequence 45| UGUGUUAGAAUAGGGGCAAUAA |66
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN8332435 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1056852374 2 dbSNP
rs894329932 11 dbSNP
rs1429410622 12 dbSNP
rs13299349 13 dbSNP
rs539052066 14 dbSNP
rs1028341616 15 dbSNP
rs969346701 16 dbSNP
rs1176815888 19 dbSNP
rs1474970048 19 dbSNP
rs1240079601 21 dbSNP
Putative Targets

Gene Information
Gene Symbol LAMP2   
Synonyms CD107b, LAMP-2, LAMPB, LGP-96, LGP110
Description lysosomal associated membrane protein 2
Transcript NM_002294   
Other Transcripts NM_001122606 , NM_013995   
Expression
Putative miRNA Targets on LAMP2
3'UTR of LAMP2
(miRNA target sites are highlighted)		 
>LAMP2|NM_002294|3'UTR
   1 AATCTGCAACCTGATTGATTATATAAAAATACATGCAAATAACAAGATTTTCTTACCTCTCAGTTGTTGAAACACTTTGC
  81 TTCTTAAAATTGATATGTTGAAACTTTAATTCTTTTATCAATCCCAGCATTTTGAGATCAGTCTTTATTAATAAAACCTG
 161 TTCTCTTTAATCAGCTTAAAATCCAAAGTGTCATATTTACTGGTCCTGGAGACAAACTTGTTCAAAAGAACATCAACGTG
 241 CAATGTTTTAAGGTCTATCTTAAGAAGCCCTGGCCAAATTTTGATCCTAACCTTGAAGTATGCCTTGAACTTATTAACAT
 321 GGCCATTATAAGAATAAAATATGTAGTTGTGTCTTAATGGAATTAATAAATGTCATTTCACTACTGGTGTTCTGTTTCAA
 401 TGTATAAGGACTATAGTGATTTAAACTCATCAATGTGCCTTTGCATAAAGTTCATTAAATAAATATTGATGTGGTATAAA
 481 TGCCCATCAGATATGCTTAAACTTGGTTTTCAGTTGAATGAAGTAGAGAATGTCCTCAGGACCATCAGCATTTTAAAGGT
 561 TATGTGACTTTTGCTGATTTCTCTGAGTTCAAGTTAAGCATGAAGTTAGTACCTCAAGCCTGTGATTTTTCCCTAGGGAT
 641 GATACAGACCCAAGAGGCTACAACAGAACTTAAACTGGCTTCGTAATTAGAGTTTTTAAGATAATTGTTTGTTTTTCAGC
 721 AATATAGACTGAAAAGATCCAAGCATATTTAGCCACTTGCTTTTTTGTTTCTTGTTTTGTTCTTCTTTGGATGCCTGATT
 801 AGTATTGAAAGATAGAAATATTCTATGAACTAATTAGGACAGATTGTGTTGTGTTTCTCTACCTCATCTTGTTGATCTCT
 881 GGAGCATTAAAATCTATTTAGTGTTGTCATCAGTGTGGTACTTATGAAATGTAAGCTAACAGCAATCTCAGAAGGGAGGC
 961 AGTGAAGCATAGCAACTAGGCTCTTGTTTCTTCAAGATGGCCCCTGTGGGGCAGTGCATAGATGGGGGTGTAAAGAGAAG
1041 CTGTTGGCATTAAAATGAGCTAGATAATCAGCCCTTGTTGAAGCATATTCCATGGTATAAGAGTAGCACAGACATGAAAC
1121 ATAGATAAAGAAGGAAGGCTTAATAGACTAGAAGACTTCCACATTGAAGTATTATTAACCCATTGTATGTATATAGGGGC
1201 ATGATCAGAGTCTCTATAACTTCCTGATTAACAATACAGTGTATCTTGTTACCCAGCTGTCAGTCTTTGAGAGCTTTCAG
1281 TAAAATATAGTAAATTCTTTCAGCATAGGCTAATGTGTGGTTACTGAGATGAGTGTTGTGTACTCAGAACCGTAGCAACA
1361 TTTTTATGAATGGTAAAAGTACAAGAGGAGGAAAAGTTAAAATTAGAAGAAAAGTACAAGTTATTGCTTAATCATAAATC
1441 ACACCAGATAACACATTTTGTTAATTTCATTAGCTATTACTGGAAAGGACCTTAACGATTATTTACAGAAAGGGGAGTGA
1521 AATTCATTGAGGTTCCATATCAAGTGGGCAACAAAACTATTACTAGCATTTTGATAAAAATTGCCCCTAATGAAATCTAG
1601 TCACTCAACAGTAAAACAACAGCTGGTTTACACTTGAAATTATGAGATCAGAATTGGGCACTTTGGGCTTCCGTACTATG
1681 TTTTGCTTAAGTTTTTTTTTTAATACTAATATGGGCTTTTTCAGTAGTAATATACCAAAACACTTCTATTTTAATCTCTG
1761 TTTGCTACTTCAAAACCTAATCCTCCTCAGATGGGATCATGAGCATAAGAGGAAAAGAGAAGAGAATGAATACTTGTTGA
1841 CCTCTTGATGTGTATCAGATGCTTTAGAAATGTAATTGTATTTAATCCTCAAATACCTTATAGGTATTATTATCCCCTTC
1921 TTACAGATGAGGAAAGTGAGGCCCAGTTTAAATAACTTGCCCAAGGTCCTTTGGCTAGTACTGGAAGGAGTCAAGATTTA
2001 AACACAGTTCTGTCTGAATCCAGAACTCAAAATCTACATTGCACATGTTGCTTTCCTGGTGGTTCGGTGGAATGGACTGC
2081 AACGCATTAGATACTGCTGTTATTCTTCCAGGCCACCGCTCAGCTAAAAATAATTGTGTGTGTGTGTATATATATATATA
2161 TGTACACACACACACATATATATACACACACACATATATATACACATATACATATATATACACATATATATACACACACA
2241 TATATATGTATATATATACTACATTCTTGATCCTAAGTCTTTTTTAACTTAAATTTTATTACTTATACAGAATTCTTATT
2321 TATACTTTAATTATAGGTGTGACGAAGAGAAAGAGAGTAGGGAAATACACAGGCAGTGGTTTTAAGTGTAGATGATGGCT
2401 CCTTAACCCAGTGTCATTAGATAATCAAACCTAAAGTCTTCCCATATTAGGCAAGCGCAATTCTCTATTTTGGACCCTTC
2481 CCATTCTTCCCTTACCTTCTGCTTTTCGTACTGAGGAATTTCGTGTGATTTTAGATAAAGTGATAATGAGATATTGAGCA
2561 AATAAGAAAATAGAGGTAATGCTATAAAAAACTAAGCTATGTACACTTTCAAAATGCATGTTTCTTGCATGCTTTTTACT
2641 ACTTAATTGCATTCTTTGCTAATTTCCTTTCCTTGCTGTCTGTTCTTTTCTAACAGCTGAAGAATGTTCTGCTGACTCTG
2721 ACCTCAACTTTCTTATTCCTGTTGCAGTGGGTGTGGCCTTGGGCTTCCTTATAATTGTTGTCTTTATCTCTTATATGATT
2801 GGAAGAAGGAAAAGTCGTACTGGTTATCAGTCTGTGTAATCAGTTAAATCTAGTGTTTGTTTGTTTTTTTCAATTAGAAG
2881 TTACGTTTCCATTGGCTAAAAGCCAGGACATGCTGTGCAATAGATTGTTTAAGATATGCAGACTAACTTCAGTGAGTTCC
2961 TAGCTAACTTGGGCATGAGTACACTTATTTAAGACAAAATATATTAGGACCAATTTTTTTCTGTTTTTTTTCTTCCTTTG
3041 TTAAAGTATAATTAAAAGAAAAATTGTGGCTTAGAATTTTTTAAGTAAATAATGATTTTAAGCCCCTGGATCCAATTATG
3121 AAAGCATTTTTGCTGATGTGTAATTTTATATGTTACAGTTACTTATATTTTACTACTTTGATGTTATTTGCAAAATCAAA
3201 GGTGTTAAAGAATTTAACTTGCTTCAGGAAATAAATTCAAGAACATAGTGGATTCATTTTCATTGGTGGCAGACACGAAA
3281 TTTGGTTCATGATAAGACTTCCTTTCCCCACCTCCTGATCAGCATTATTTAAATCTGTATTTTTCTGTTAGTTAAGAAAG
3361 AAATGGCTTCATGATATTGTATTTAATAGCAAAAGTTTGGCTGTCTTCTTCATTACTGTTAATAGCTACTATATTTTAAC
3441 AAGGAGATTTCTTTTTTTGTTGTTGTTGTTCTAGAGTTTGGAATATACTGATTATCTCAGACTTGACATTTATACTGAAG
3521 GATGAAGTAAGACCTCCAGCTTTTTTTAAAAAAGGTGTTGATTTGGAACACCTGTATGGGTTATGGTTTATTAAGGTTAT
3601 GGTTTAGAAAGTTTTTTTCCCTCAGAGCCTTAACTTGTTAAGAAGGTTCATTTATCCTGCACTGAAAACAAAAACTCTAT
3681 ATACTTTGTTTGTGTGCCTCCTGCACTCTCCCATTCCCTATGTGAATATGCTCTAGTTGATATTTTTAATATATTGATTT
3761 CTTTTTTCTCACAGCAACAAGTGCTTACTCTAGAGGTTAGTGGGCCCTGATATGTCATCAGTCAGATGCCTGCCTAGCCA
3841 AAGCTGGACTAAGATTATTCTGTACATTTGTTGATCTTGATATAGACTTATATCCCTGTAGGGACTGCTAATGGCTCCGG
3921 CTTCTGGAGTAAGGTACTGGAGACCACTCATCCCTGTGTCTGCTTGATTGGTTCAGCTGTTGAATTGCCCTTTTATTTGG
4001 AAGCAGTGTTGAAGTTGTCTAGGGTTCAAATGGCTGCTTTGTACACCTGTCATTAGTATAAGGCAGATGTTTATTTTATC
4081 AAGCTATTTTATCTCTACATTTAACTAAAAACAAAAGTTCCCAAAGATCTGCCTTCACTTCAGAAATTTTTTTTGGATTA
4161 AAAAAATTAAGCCTGAACCTTAAATAAAGTGAGTTGGTTATTCATTCCAAGGATTAAGTCCCAATCTACCTCTCAGCACA
4241 ATGCAGAAGCTCACCACTGTATTGCTGCCATTAACTCATGCCAGAACCCTTTGCCAATAACTGGAATTACAAATTTTTGT
4321 TAAAGAAAATTTATCAAGATCTTTCTTTACTGCCTTCTCTATATGTACATCTCAAAAACATGTACATCTCAAAAACTGGA
4401 GTAGAAAGTTAGATTGCTCAACTACAACTCCTCTAGAACTCTATAGCTCTGACATACAGATTCACACTCTCCTCTATTTG
4481 CTAAGTATGTAAAGAATGTTTTCTTTTAAAATGTTCTCTTTTGAGAACAACTGCTTATTTGTTATAAAAGCATTTGGTTA
4561 AAATGATGTCATCATAAAAAACAGTGGCTTTGTTTCAATACATATTTTTGAGATGATTATCTAGAAGCCAGATTAATAAA
4641 ATCAGCTTGTGACCTTGCTAAGCATATAAACTGGAAATTCAGATACATTCAAAATTATGGGTTCATTTAAAAGTGTTCTA
4721 CCTTTTGGGTATGAGACTAATATCACTAATTCCTCAATAGTTATCATGGCTCTATCTTAATTAATTAGAAAATATGTGTG
4801 TTTAATTCTTTGAGAATTAAAATAGAGAATATTAACAGAGGGTTAAAAACTGCTTCAACTCCAATAAGATAAAGGAAGCT
4881 CAAAATCTATGAGCTGAGTGTTCAATTAGCTTTGCCTACTGAGTTCAATTTTATGTCAATACAACAGTGGATCAGACAGT
4961 ACGACTTTGAACTGGTGAATGTAAACAATTGTTTTTCACCTAAGCTGCTTTGGAAGAACTGATGCTTGCTGCTAACTAAA
5041 GTTTTGGATGTATCGATTTAGAGAACCAATTAATACCTGCAAAATAAAGCATACTGTGGTACTTCTGTTTGATCTAGTAT
5121 GTGTGATTTTAGATTGATGGATTAAAAATTAATAAAGATCATACATTCCATACCAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aauaACGGGGAUAAGAUUGUgu 5'
              ||::|:| ||||||||  
Target 5' tgtcTGTTCTT-TTCTAACAgc 3'
 2677 - 2697 145.00 -12.60
2 
miRNA  3' aaUAACG--GGGAUAAGAUUGUgu 5'
            || ||  |: ||||:|||||  
Target 5' taATAGCTACTATATTTTAACAag 3'
 3420 - 3443 134.00 -9.60
3 
miRNA  3' aaUAACGGGGA-UA----AGAUU-GUGu 5'
            ||||||||| ||    ||||: ||| 
Target 5' aaATTGCCCCTAATGAAATCTAGTCACt 3'
 1578 - 1605 130.00 -18.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
179016 15 ClinVar
367785 33 ClinVar
367784 205 ClinVar
1208755 237 ClinVar
912657 238 ClinVar
367783 297 ClinVar
367782 477 ClinVar
367781 486 ClinVar
367780 586 ClinVar
367779 653 ClinVar
367778 692 ClinVar
367777 721 ClinVar
367776 853 ClinVar
914618 975 ClinVar
367775 1071 ClinVar
367774 1096 ClinVar
367773 1191 ClinVar
914617 1243 ClinVar
367772 1314 ClinVar
367771 1356 ClinVar
914114 1413 ClinVar
367770 1589 ClinVar
367769 1617 ClinVar
367768 1632 ClinVar
367767 1672 ClinVar
367766 1702 ClinVar
367765 2005 ClinVar
914113 2147 ClinVar
367764 2148 ClinVar
367761 2162 ClinVar
367762 2162 ClinVar
367763 2162 ClinVar
367760 2183 ClinVar
367759 2195 ClinVar
367758 2261 ClinVar
367757 2395 ClinVar
367756 2460 ClinVar
913721 2476 ClinVar
913720 2518 ClinVar
367755 2524 ClinVar
367754 2538 ClinVar
912620 2575 ClinVar
367753 2736 ClinVar
43956 2746 ClinVar
1176953 2752 ClinVar
43957 2773 ClinVar
912619 2794 ClinVar
912618 2955 ClinVar
367752 3032 ClinVar
367751 3248 ClinVar
367750 3249 ClinVar
914581 3263 ClinVar
914580 3276 ClinVar
367749 3355 ClinVar
914579 3413 ClinVar
914578 3452 ClinVar
914577 3459 ClinVar
367748 3471 ClinVar
914576 3488 ClinVar
914575 3494 ClinVar
914067 3563 ClinVar
914066 3583 ClinVar
367747 3677 ClinVar
367746 3687 ClinVar
367745 3689 ClinVar
914065 4004 ClinVar
914064 4006 ClinVar
367744 4562 ClinVar
367743 4579 ClinVar
913670 4664 ClinVar
367742 4671 ClinVar
913669 4757 ClinVar
367741 4763 ClinVar
367740 4858 ClinVar
367739 4961 ClinVar
367738 4964 ClinVar
367737 5038 ClinVar
367736 5048 ClinVar
367735 5172 ClinVar
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1389561037 8 dbSNP
rs1193961180 9 dbSNP
rs376806600 15 dbSNP
rs935426216 20 dbSNP
rs1474057100 21 dbSNP
rs753374435 24 dbSNP
rs1315522163 26 dbSNP
rs1203163355 31 dbSNP
rs745798436 33 dbSNP
rs903963937 41 dbSNP
rs891188414 42 dbSNP
rs1332177028 45 dbSNP
rs1439372411 49 dbSNP
rs1196417658 72 dbSNP
rs1178770428 73 dbSNP
rs768475790 75 dbSNP
rs1480682300 84 dbSNP
rs1201495258 90 dbSNP
rs1050285762 96 dbSNP
rs1461524403 97 dbSNP
rs778938403 112 dbSNP
rs749090092 124 dbSNP
rs757173953 124 dbSNP
rs1403968956 139 dbSNP
rs898643725 150 dbSNP
rs542576305 152 dbSNP
rs1038575879 155 dbSNP
rs1272173313 172 dbSNP
rs1213705229 181 dbSNP
rs1366578608 203 dbSNP
rs41300191 205 dbSNP
rs1265758827 209 dbSNP
rs1238954574 224 dbSNP
rs908795462 236 dbSNP
rs143070918 237 dbSNP
rs1226004799 241 dbSNP
rs371031457 257 dbSNP
rs753133641 260 dbSNP
rs917617678 267 dbSNP
rs1801135 296 dbSNP
rs8160 297 dbSNP
rs1490448572 300 dbSNP
rs959191331 310 dbSNP
rs755520529 314 dbSNP
rs1224691745 319 dbSNP
rs766396944 321 dbSNP
rs1428020389 325 dbSNP
rs1375007847 342 dbSNP
rs758434357 350 dbSNP
rs1471971639 390 dbSNP
rs1032582981 400 dbSNP
rs1163163365 406 dbSNP
rs1366639073 428 dbSNP
rs749885888 430 dbSNP
rs1426913848 446 dbSNP
rs750939378 477 dbSNP
rs185972753 485 dbSNP
rs5957383 486 dbSNP
rs386827301 487 dbSNP
rs1318327300 492 dbSNP
rs1008155913 495 dbSNP
rs1452930600 514 dbSNP
rs1242228354 523 dbSNP
rs1313895378 525 dbSNP
rs1364360913 527 dbSNP
rs1247844288 541 dbSNP
rs756938982 550 dbSNP
rs891114974 555 dbSNP
rs916829066 557 dbSNP
rs1205641246 558 dbSNP
rs1028350037 560 dbSNP
rs997340226 565 dbSNP
rs1264020326 567 dbSNP
rs181333906 583 dbSNP
rs41312757 586 dbSNP
rs1038903198 590 dbSNP
rs918266438 620 dbSNP
rs1157168627 635 dbSNP
rs1363729461 638 dbSNP
rs1193866796 639 dbSNP
rs972481170 651 dbSNP
rs1057515744 653 dbSNP
rs1469587906 656 dbSNP
rs940187990 657 dbSNP
rs962764576 663 dbSNP
rs1259019950 683 dbSNP
rs184344224 684 dbSNP
rs1057515743 692 dbSNP
rs1351970339 693 dbSNP
rs1306892472 702 dbSNP
rs1316105982 707 dbSNP
rs1263051881 708 dbSNP
rs761300966 715 dbSNP
rs1057515742 721 dbSNP
rs887326511 721 dbSNP
rs985690345 725 dbSNP
rs1343002948 731 dbSNP
rs1203064520 736 dbSNP
rs1347623215 742 dbSNP
rs1243987669 756 dbSNP
rs1304698805 761 dbSNP
rs1462770076 767 dbSNP
rs1176993966 779 dbSNP
rs1250322565 788 dbSNP
rs1420025882 805 dbSNP
rs1046000020 806 dbSNP
rs1184651590 821 dbSNP
rs1376386724 825 dbSNP
rs1467793950 842 dbSNP
rs1175004894 843 dbSNP
rs1443366669 848 dbSNP
rs763861761 853 dbSNP
rs917570754 877 dbSNP
rs775142637 878 dbSNP
rs1391724158 886 dbSNP
rs937724187 890 dbSNP
rs925059882 896 dbSNP
rs1343497810 901 dbSNP
rs771496857 904 dbSNP
rs1222984901 909 dbSNP
rs762796984 924 dbSNP
rs901821982 925 dbSNP
rs1197038483 944 dbSNP
rs1250939471 950 dbSNP
rs1481181108 974 dbSNP
rs1179268991 975 dbSNP
rs1265890497 980 dbSNP
rs368723660 1002 dbSNP
rs1480436358 1006 dbSNP
rs966530783 1018 dbSNP
rs1031405542 1024 dbSNP
rs1481116418 1025 dbSNP
rs1432852397 1026 dbSNP
rs1353514264 1027 dbSNP
rs1394247518 1027 dbSNP
rs1020774241 1028 dbSNP
rs999554973 1029 dbSNP
rs1174072762 1030 dbSNP
rs903930986 1031 dbSNP
rs759105844 1041 dbSNP
rs1455291415 1043 dbSNP
rs1043853074 1049 dbSNP
rs986663835 1057 dbSNP
rs955333158 1062 dbSNP
rs2285548 1071 dbSNP
rs770959886 1074 dbSNP
rs1206884588 1088 dbSNP
rs1264113499 1092 dbSNP
rs5957382 1096 dbSNP
rs1223939982 1124 dbSNP
rs181690821 1125 dbSNP
rs1017030849 1164 dbSNP
rs939598084 1182 dbSNP
rs1004327482 1191 dbSNP
rs1057515741 1191 dbSNP
rs887254365 1196 dbSNP
rs972792122 1200 dbSNP
rs1423729007 1204 dbSNP
rs941076536 1213 dbSNP
rs1485667008 1216 dbSNP
rs769587066 1216 dbSNP
rs1045970755 1220 dbSNP
rs1288433901 1222 dbSNP
rs147825361 1243 dbSNP
rs894734694 1248 dbSNP
rs1359219778 1257 dbSNP
rs1247115321 1269 dbSNP
rs985178749 1273 dbSNP
rs1294607737 1288 dbSNP
rs1377284400 1291 dbSNP
rs1445716143 1299 dbSNP
rs1215694016 1305 dbSNP
rs1241069282 1306 dbSNP
rs953856280 1308 dbSNP
rs1187937542 1312 dbSNP
rs5957381 1314 dbSNP
rs937710864 1322 dbSNP
rs140499497 1325 dbSNP
rs1398940569 1334 dbSNP
rs772626501 1334 dbSNP
rs1158260092 1350 dbSNP
rs1328263172 1351 dbSNP
rs188897063 1356 dbSNP
rs1432928705 1364 dbSNP
rs1335001085 1380 dbSNP
rs1382236383 1382 dbSNP
rs747215176 1391 dbSNP
rs976581946 1399 dbSNP
rs1317693811 1410 dbSNP
rs1348963259 1411 dbSNP
rs773379092 1413 dbSNP
rs1374827738 1428 dbSNP
rs772282965 1430 dbSNP
rs956130181 1435 dbSNP
rs1285534326 1442 dbSNP
rs1317021019 1450 dbSNP
rs1210002064 1465 dbSNP
rs1260880140 1469 dbSNP
rs986632884 1476 dbSNP
rs779447908 1486 dbSNP
rs1031625569 1489 dbSNP
rs185680374 1492 dbSNP
rs1468382621 1496 dbSNP
rs1166981048 1497 dbSNP
rs1176584373 1512 dbSNP
rs754306794 1527 dbSNP
rs1402541155 1547 dbSNP
rs1374286210 1560 dbSNP
rs1174287559 1568 dbSNP
rs1405439544 1570 dbSNP
rs1185206835 1573 dbSNP
rs73612906 1589 dbSNP
rs1258852927 1603 dbSNP
rs1022764315 1605 dbSNP
rs141881232 1617 dbSNP
rs1376092866 1623 dbSNP
rs1229701680 1626 dbSNP
rs755434692 1632 dbSNP
rs895288139 1639 dbSNP
rs752352307 1642 dbSNP
rs1017380403 1652 dbSNP
rs1203950659 1654 dbSNP
rs1004293028 1662 dbSNP
rs951483166 1666 dbSNP
rs1024440041 1672 dbSNP
rs1057515740 1672 dbSNP
rs1014439065 1673 dbSNP
rs1473573026 1686 dbSNP
rs1197178761 1702 dbSNP
rs1232779354 1702 dbSNP
rs373005118 1702 dbSNP
rs1480785684 1704 dbSNP
rs1178886772 1712 dbSNP
rs894689376 1715 dbSNP
rs1003736941 1730 dbSNP
rs1329883195 1743 dbSNP
rs1356635085 1758 dbSNP
rs1283170536 1776 dbSNP
rs759156736 1776 dbSNP
rs1344358027 1785 dbSNP
rs897397344 1789 dbSNP
rs1037293345 1793 dbSNP
rs940985042 1823 dbSNP
rs1213627201 1830 dbSNP
rs1273524163 1836 dbSNP
rs909567277 1856 dbSNP
rs551726898 1858 dbSNP
rs1056068322 1861 dbSNP
rs1268043547 1872 dbSNP
rs1000877206 1887 dbSNP
rs903504008 1894 dbSNP
rs1049439288 1896 dbSNP
rs1352527356 1902 dbSNP
rs1328008256 1903 dbSNP
rs1475247047 1914 dbSNP
rs1168697856 1941 dbSNP
rs770516462 1950 dbSNP
rs1392461928 1952 dbSNP
rs1410148476 1964 dbSNP
rs1423087921 1965 dbSNP
rs1303105440 1978 dbSNP
rs763011446 1979 dbSNP
rs148513908 1984 dbSNP
rs5956215 1993 dbSNP
rs747959447 1995 dbSNP
rs200014321 2005 dbSNP
rs913654360 2022 dbSNP
rs193230112 2023 dbSNP
rs1050858234 2029 dbSNP
rs372028662 2035 dbSNP
rs746044334 2035 dbSNP
rs976549455 2036 dbSNP
rs1344078248 2048 dbSNP
rs933860298 2051 dbSNP
rs955931127 2053 dbSNP
rs1359981474 2064 dbSNP
rs924491995 2065 dbSNP
rs978706985 2066 dbSNP
rs1194207669 2076 dbSNP
rs749840453 2077 dbSNP
rs1250082730 2079 dbSNP
rs1443183037 2081 dbSNP
rs1163266130 2083 dbSNP
rs921122080 2083 dbSNP
rs975344543 2084 dbSNP
rs1459953139 2086 dbSNP
rs780826840 2088 dbSNP
rs909882055 2091 dbSNP
rs756779550 2099 dbSNP
rs1381121136 2105 dbSNP
rs1469115449 2109 dbSNP
rs779000030 2117 dbSNP
rs1366841495 2118 dbSNP
rs867197855 2144 dbSNP
rs868133941 2146 dbSNP
rs1314194515 2147 dbSNP
rs1383239220 2148 dbSNP
rs756504749 2148 dbSNP
rs778330920 2148 dbSNP
rs187660648 2149 dbSNP
rs753072593 2149 dbSNP
rs1022319055 2150 dbSNP
rs1271545550 2151 dbSNP
rs1213081216 2154 dbSNP
rs1467961011 2162 dbSNP
rs753399289 2162 dbSNP
rs765988404 2162 dbSNP
rs767123866 2162 dbSNP
rs769125462 2162 dbSNP
rs1321481694 2163 dbSNP
rs1184952088 2165 dbSNP
rs1413592421 2165 dbSNP
rs1175294544 2167 dbSNP
rs1479152538 2167 dbSNP
rs1359320915 2169 dbSNP
rs751146184 2169 dbSNP
rs184297875 2171 dbSNP
rs191802231 2175 dbSNP
rs1395492431 2176 dbSNP
rs1309745569 2177 dbSNP
rs1343759570 2177 dbSNP
rs1410412183 2177 dbSNP
rs1222924760 2179 dbSNP
rs1275193178 2183 dbSNP
rs765214315 2183 dbSNP
rs1314093389 2184 dbSNP
rs1225506311 2185 dbSNP
rs1021874745 2188 dbSNP
rs1009203820 2189 dbSNP
rs1251160843 2191 dbSNP
rs1207970317 2195 dbSNP
rs13441024 2195 dbSNP
rs1481151389 2195 dbSNP
rs1197985068 2197 dbSNP
rs1371142804 2197 dbSNP
rs1434605690 2203 dbSNP
rs776510193 2203 dbSNP
rs1442685376 2207 dbSNP
rs1372325072 2208 dbSNP
rs1378603963 2219 dbSNP
rs1170442571 2221 dbSNP
rs1363580134 2221 dbSNP
rs1404419576 2222 dbSNP
rs768404397 2231 dbSNP
rs1323485755 2233 dbSNP
rs1369806539 2233 dbSNP
rs1295088140 2237 dbSNP
rs200167553 2237 dbSNP
rs1343356574 2238 dbSNP
rs1394559240 2241 dbSNP
rs959426611 2244 dbSNP
rs1359439180 2248 dbSNP
rs1050785935 2260 dbSNP
rs12395643 2261 dbSNP
rs1407924237 2277 dbSNP
rs556281238 2286 dbSNP
rs1159473441 2309 dbSNP
rs1184435156 2322 dbSNP
rs1260542600 2329 dbSNP
rs1471365499 2330 dbSNP
rs1170179224 2334 dbSNP
rs899658481 2337 dbSNP
rs1383153364 2338 dbSNP
rs1251315541 2343 dbSNP
rs752409883 2344 dbSNP
rs111473686 2350 dbSNP
rs1469123645 2353 dbSNP
rs771058435 2354 dbSNP
rs941248591 2361 dbSNP
rs539545568 2370 dbSNP
rs1288525214 2372 dbSNP
rs982751526 2378 dbSNP
rs1437540358 2387 dbSNP
rs1313448425 2388 dbSNP
rs10127185 2395 dbSNP
rs756620818 2398 dbSNP
rs917277564 2402 dbSNP
rs1229432628 2407 dbSNP
rs1292592488 2408 dbSNP
rs1315002948 2409 dbSNP
rs1283515005 2411 dbSNP
rs1212970747 2413 dbSNP
rs1224065159 2421 dbSNP
rs992912231 2446 dbSNP
rs959075617 2449 dbSNP
rs1241098501 2453 dbSNP
rs1443751521 2455 dbSNP
rs1034519722 2456 dbSNP
rs1415814201 2457 dbSNP
rs10127182 2460 dbSNP
rs781643131 2475 dbSNP
rs776684734 2476 dbSNP
rs1334928153 2494 dbSNP
rs1405847665 2502 dbSNP
rs1049364819 2507 dbSNP
rs932356911 2508 dbSNP
rs755322977 2514 dbSNP
rs922345485 2517 dbSNP
rs56158197 2518 dbSNP
rs766113990 2521 dbSNP
rs758046468 2522 dbSNP
rs934452871 2523 dbSNP
rs150119198 2524 dbSNP
rs187346492 2537 dbSNP
rs1057515739 2538 dbSNP
rs979060016 2551 dbSNP
rs772262558 2571 dbSNP
rs77126790 2575 dbSNP
rs202199842 2586 dbSNP
rs776369585 2596 dbSNP
rs968652018 2603 dbSNP
rs763889562 2606 dbSNP
rs915855009 2610 dbSNP
rs182654000 2625 dbSNP
rs200780311 2627 dbSNP
rs1397139677 2632 dbSNP
rs888341351 2634 dbSNP
rs1184811293 2644 dbSNP
rs201640841 2652 dbSNP
rs929905079 2661 dbSNP
rs1326365726 2666 dbSNP
rs750418202 2671 dbSNP
rs767422843 2674 dbSNP
rs990817509 2676 dbSNP
rs763082089 2677 dbSNP
rs775547188 2678 dbSNP
rs1425986613 2680 dbSNP
rs1168595457 2683 dbSNP
rs1350606806 2711 dbSNP
rs765285068 2720 dbSNP
rs1229647863 2721 dbSNP
rs769795421 2722 dbSNP
rs1280989303 2732 dbSNP
rs759814013 2734 dbSNP
rs1057515738 2736 dbSNP
rs776665496 2745 dbSNP
rs3827478 2746 dbSNP
rs1212813867 2752 dbSNP
rs1466883574 2753 dbSNP
rs1274595954 2755 dbSNP
rs1195888609 2766 dbSNP
rs747304113 2771 dbSNP
rs397516587 2773 dbSNP
rs372396556 2780 dbSNP
rs760540948 2782 dbSNP
rs1035062584 2791 dbSNP
rs368937075 2794 dbSNP
rs749374058 2795 dbSNP
rs1252385133 2797 dbSNP
rs1484083055 2804 dbSNP
rs778580428 2807 dbSNP
rs754397650 2815 dbSNP
rs375994314 2816 dbSNP
rs1174359442 2817 dbSNP
rs1455569835 2820 dbSNP
rs143420310 2857 dbSNP
rs755988734 2860 dbSNP
rs1452279534 2864 dbSNP
rs769717509 2867 dbSNP
rs773163247 2867 dbSNP
rs1174515796 2871 dbSNP
rs761717112 2871 dbSNP
rs767240416 2871 dbSNP
rs373841690 2873 dbSNP
rs761747329 2875 dbSNP
rs376318727 2884 dbSNP
rs773987053 2884 dbSNP
rs759490403 2885 dbSNP
rs978931351 2887 dbSNP
rs780055219 2891 dbSNP
rs913433547 2896 dbSNP
rs749628026 2902 dbSNP
rs954998938 2905 dbSNP
rs1360650138 2908 dbSNP
rs190781020 2909 dbSNP
rs996431786 2910 dbSNP
rs1436800741 2914 dbSNP
rs1029292416 2915 dbSNP
rs780640930 2919 dbSNP
rs1374220732 2933 dbSNP
rs756720313 2937 dbSNP
rs1227318319 2942 dbSNP
rs1275264834 2955 dbSNP
rs963800915 2956 dbSNP
rs1344320251 2961 dbSNP
rs1220147800 2965 dbSNP
rs1266827259 2980 dbSNP
rs1018459771 2991 dbSNP
rs1452223693 3009 dbSNP
rs1240527784 3014 dbSNP
rs1449256764 3021 dbSNP
rs1189539814 3024 dbSNP
rs1040749550 3032 dbSNP
rs113549733 3032 dbSNP
rs755451497 3032 dbSNP
rs747372256 3036 dbSNP
rs934442233 3038 dbSNP
rs188577917 3043 dbSNP
rs1325129139 3045 dbSNP
rs878924268 3068 dbSNP
rs758148695 3074 dbSNP
rs1361043476 3090 dbSNP
rs888267430 3099 dbSNP
rs1046964683 3113 dbSNP
rs1298143968 3116 dbSNP
rs1367071084 3135 dbSNP
rs994081471 3136 dbSNP
rs1420310001 3144 dbSNP
rs1264756474 3158 dbSNP
rs902963068 3161 dbSNP
rs895736350 3162 dbSNP
rs1211656700 3169 dbSNP
rs1057096447 3178 dbSNP
rs1464669896 3197 dbSNP
rs1478734344 3203 dbSNP
rs1209571000 3212 dbSNP
rs750004511 3240 dbSNP
rs5957380 3248 dbSNP
rs41300908 3249 dbSNP
rs1042879151 3258 dbSNP
rs1472841082 3262 dbSNP
rs1164559557 3263 dbSNP
rs1385794924 3268 dbSNP
rs1043524915 3276 dbSNP
rs915823771 3277 dbSNP
rs183969784 3281 dbSNP
rs1257606942 3284 dbSNP
rs1390605341 3288 dbSNP
rs1202004582 3306 dbSNP
rs1311943735 3315 dbSNP
rs991413172 3329 dbSNP
rs947510985 3345 dbSNP
rs937970518 3348 dbSNP
rs764018077 3355 dbSNP
rs913402046 3373 dbSNP
rs1354066765 3377 dbSNP
rs192151171 3385 dbSNP
rs1415718480 3389 dbSNP
rs1270193585 3399 dbSNP
rs954925800 3400 dbSNP
rs1200168069 3403 dbSNP
rs923532725 3411 dbSNP
rs1444689286 3412 dbSNP
rs1180263874 3413 dbSNP
rs1409185570 3447 dbSNP
rs752469856 3452 dbSNP
rs961465393 3454 dbSNP
rs1413642174 3456 dbSNP
rs185990694 3459 dbSNP
rs1172857287 3462 dbSNP
rs1302115428 3462 dbSNP
rs1017967240 3469 dbSNP
rs199705754 3471 dbSNP
rs773236667 3488 dbSNP
rs180681121 3494 dbSNP
rs984295896 3505 dbSNP
rs1025442054 3507 dbSNP
rs1321750519 3508 dbSNP
rs1232785704 3512 dbSNP
rs1257008678 3534 dbSNP
rs994007432 3547 dbSNP
rs1251669182 3548 dbSNP
rs761785059 3548 dbSNP
rs1182187864 3553 dbSNP
rs895703713 3554 dbSNP
rs1431152994 3555 dbSNP
rs1257978983 3571 dbSNP
rs1175310889 3572 dbSNP
rs1480076407 3578 dbSNP
rs1057414175 3580 dbSNP
rs144504054 3583 dbSNP
rs905852522 3584 dbSNP
rs1467342475 3586 dbSNP
rs866262882 3589 dbSNP
rs1272052808 3590 dbSNP
rs997076114 3592 dbSNP
rs1410353566 3595 dbSNP
rs1309995359 3607 dbSNP
rs947436311 3608 dbSNP
rs189695743 3628 dbSNP
rs1053188410 3638 dbSNP
rs752459076 3648 dbSNP
rs1057515737 3677 dbSNP
rs1302201183 3682 dbSNP
rs185627568 3687 dbSNP
rs1057515736 3689 dbSNP
rs975386272 3689 dbSNP
rs1305246794 3694 dbSNP
rs943667258 3702 dbSNP
rs910876111 3704 dbSNP
rs998951184 3706 dbSNP
rs1276218532 3718 dbSNP
rs1374243903 3739 dbSNP
rs1333634473 3743 dbSNP
rs1439060551 3748 dbSNP
rs983789027 3750 dbSNP
rs1165805820 3789 dbSNP
rs1186510347 3790 dbSNP
rs1389302905 3796 dbSNP
rs1430383032 3813 dbSNP
rs1170384342 3825 dbSNP
rs1348241748 3828 dbSNP
rs1043232540 3829 dbSNP
rs1294359976 3866 dbSNP
rs1458330599 3873 dbSNP
rs952405441 3877 dbSNP
rs181132832 3894 dbSNP
rs1055691874 3896 dbSNP
rs1025409360 3910 dbSNP
rs1238343886 3911 dbSNP
rs1319417124 3918 dbSNP
rs1180108373 3919 dbSNP
rs1466911169 3929 dbSNP
rs972536036 3934 dbSNP
rs754740000 3940 dbSNP
rs1265505735 3941 dbSNP
rs960132878 3943 dbSNP
rs1489289233 3949 dbSNP
rs1206410992 3952 dbSNP
rs1035565163 3958 dbSNP
rs1209964388 3968 dbSNP
rs1449808254 3977 dbSNP
rs1190462536 4000 dbSNP
rs1001857275 4004 dbSNP
rs905784906 4006 dbSNP
rs1489731000 4008 dbSNP
rs1430103377 4019 dbSNP
rs1021547844 4049 dbSNP
rs908587886 4055 dbSNP
rs984613119 4069 dbSNP
rs1389868140 4082 dbSNP
rs772259249 4098 dbSNP
rs952860374 4100 dbSNP
rs1011547358 4124 dbSNP
rs1238710994 4132 dbSNP
rs891857427 4147 dbSNP
rs1229376154 4155 dbSNP
rs1317885695 4155 dbSNP
rs1312866594 4188 dbSNP
rs1336253984 4196 dbSNP
rs1053114556 4208 dbSNP
rs921447258 4212 dbSNP
rs1312008788 4224 dbSNP
rs933435483 4227 dbSNP
rs1217601223 4232 dbSNP
rs975584009 4236 dbSNP
rs745547671 4245 dbSNP
rs1232334651 4257 dbSNP
rs1370600476 4265 dbSNP
rs1326599244 4266 dbSNP
rs13460 4275 dbSNP
rs1388621940 4277 dbSNP
rs1471622484 4285 dbSNP
rs902000009 4289 dbSNP
rs778421977 4297 dbSNP
rs1158721773 4304 dbSNP
rs1392706920 4332 dbSNP
rs1459016292 4339 dbSNP
rs1332669697 4353 dbSNP
rs1358921964 4361 dbSNP
rs1039243091 4369 dbSNP
rs943576324 4373 dbSNP
rs1356842381 4382 dbSNP
rs1380677424 4386 dbSNP
rs1287334122 4399 dbSNP
rs1020326522 4424 dbSNP
rs998524759 4425 dbSNP
rs1276303973 4430 dbSNP
rs967458267 4431 dbSNP
rs1210768372 4434 dbSNP
rs909472598 4440 dbSNP
rs1259454725 4441 dbSNP
rs1452161976 4443 dbSNP
rs756862897 4452 dbSNP
rs1181634505 4457 dbSNP
rs1198872796 4463 dbSNP
rs1473721107 4468 dbSNP
rs1452848617 4485 dbSNP
rs1259129532 4519 dbSNP
rs1205058030 4534 dbSNP
rs142200759 4562 dbSNP
rs1288578426 4568 dbSNP
rs42885 4579 dbSNP
rs1429673988 4582 dbSNP
rs190092370 4583 dbSNP
rs540341520 4587 dbSNP
rs1306936755 4588 dbSNP
rs766259260 4619 dbSNP
rs959857358 4622 dbSNP
rs760657814 4623 dbSNP
rs752588468 4627 dbSNP
rs979968621 4629 dbSNP
rs1347371364 4631 dbSNP
rs970352116 4635 dbSNP
rs1366661875 4651 dbSNP
rs1219521665 4661 dbSNP
rs894257602 4664 dbSNP
rs1045953 4671 dbSNP
rs1204317993 4715 dbSNP
rs1275488466 4720 dbSNP
rs1055617941 4721 dbSNP
rs1197050071 4728 dbSNP
rs1246289335 4729 dbSNP
rs1478565221 4733 dbSNP
rs1324746602 4740 dbSNP
rs1195972189 4745 dbSNP
rs1388696376 4755 dbSNP
rs767652057 4757 dbSNP
rs891784102 4761 dbSNP
rs761928368 4763 dbSNP
rs1036694237 4771 dbSNP
rs1299757069 4774 dbSNP
rs1432634846 4797 dbSNP
rs759191240 4798 dbSNP
rs1374410218 4808 dbSNP
rs998005364 4814 dbSNP
rs901927831 4815 dbSNP
rs774576256 4823 dbSNP
rs1436732100 4851 dbSNP
rs1057515735 4858 dbSNP
rs943561186 4858 dbSNP
rs908554155 4859 dbSNP
rs1478845068 4862 dbSNP
rs1227610188 4864 dbSNP
rs888003967 4880 dbSNP
rs768765720 4890 dbSNP
rs776018861 4893 dbSNP
rs1208072789 4934 dbSNP
rs750715219 4939 dbSNP
rs1452471304 4953 dbSNP
rs765371462 4961 dbSNP
rs1036703651 4962 dbSNP
rs1449203872 4963 dbSNP
rs754879365 4964 dbSNP
rs975551192 4968 dbSNP
rs1472092614 4975 dbSNP
rs185156571 5006 dbSNP
rs11548982 5007 dbSNP
rs746415532 5013 dbSNP
rs1412417057 5015 dbSNP
rs980320947 5018 dbSNP
rs1327449734 5019 dbSNP
rs2748 5038 dbSNP
rs1202390187 5047 dbSNP
rs113285013 5048 dbSNP
rs1321149560 5049 dbSNP
rs1250809219 5050 dbSNP
rs990017688 5054 dbSNP
rs1340978348 5055 dbSNP
rs965552504 5056 dbSNP
rs1283726456 5065 dbSNP
rs955994867 5073 dbSNP
rs747621180 5079 dbSNP
rs1235404961 5090 dbSNP
rs912781664 5105 dbSNP
rs1464741159 5106 dbSNP
rs1209821820 5118 dbSNP
rs1354579914 5132 dbSNP
rs761270364 5134 dbSNP
rs978080600 5138 dbSNP
rs1187420547 5142 dbSNP
rs1334619906 5149 dbSNP
rs1475219042 5153 dbSNP
rs1415802245 5157 dbSNP
rs1409232559 5162 dbSNP
rs778592348 5172 dbSNP
rs1158994092 5173 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545214. RNA binding protein: AGO3. Condition:Control PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aauaacggggauaaGAUUGUGu 5'
                        :|||||| 
Target 5' --------------UUAACACa 3'
 		1 - 8
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3920.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3920.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545214
Method / RBP PAR-CLIP / AGO3
Cell line / Condition HEK293 / Control
Location of target site ENST00000371335.4 | 3UTR | AUCAAAUAUUUCUUGCUGCUUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000371335.4 | 3UTR | UUAACACAUCAAAUAUUUCUUGCUGCUUCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000371335.4 | 3UTR | UUAACACAUCAAAUAUUUCUUGCUGCUUCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000371335.4 | 3UTR | UUAACACAUCAAAUAUUUCUUGCUGCUUCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000371335.4 | 3UTR | UUAACACAUCAAAUAUUUCUUGCUGCUUCUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
60 hsa-miR-3152-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT068760 RB1 RB transcriptional corepressor 1 2 2
MIRT142268 DCTN5 dynactin subunit 5 2 8
MIRT179443 TBRG1 transforming growth factor beta regulator 1 2 2
MIRT221382 DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 2 6
MIRT332510 CD81 CD81 molecule 2 2
MIRT442419 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT445519 PLXDC2 plexin domain containing 2 2 2
MIRT464185 VMA21 VMA21, vacuolar ATPase assembly factor 2 2
MIRT467933 SLC16A6 solute carrier family 16 member 6 2 2
MIRT468378 SETD5 SET domain containing 5 2 2
MIRT468486 SESN3 sestrin 3 2 2
MIRT468928 RPS24 ribosomal protein S24 2 2
MIRT478171 DENND5B DENN domain containing 5B 2 2
MIRT490447 GLUD1 glutamate dehydrogenase 1 2 2
MIRT494675 ARL5B ADP ribosylation factor like GTPase 5B 2 2
MIRT502287 GNG5 G protein subunit gamma 5 2 6
MIRT506078 PPP2CA protein phosphatase 2 catalytic subunit alpha 2 6
MIRT508008 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT508760 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT509091 SYNPO2L synaptopodin 2 like 2 4
MIRT511968 EIF1AX eukaryotic translation initiation factor 1A, X-linked 2 4
MIRT515210 CRCP CGRP receptor component 2 2
MIRT516377 TRAF3IP2 TRAF3 interacting protein 2 2 4
MIRT517047 ZNF678 zinc finger protein 678 2 2
MIRT521125 SHROOM4 shroom family member 4 2 2
MIRT521277 RTF1 RTF1 homolog, Paf1/RNA polymerase II complex component 2 2
MIRT522772 LAMP2 lysosomal associated membrane protein 2 2 6
MIRT524419 CNKSR3 CNKSR family member 3 2 2
MIRT529398 ICK intestinal cell kinase 2 2
MIRT529965 PHF7 PHD finger protein 7 2 2
MIRT530189 TIGD2 tigger transposable element derived 2 2 2
MIRT533716 TMEM30A transmembrane protein 30A 2 2
MIRT543170 FICD FIC domain containing 2 2
MIRT548496 E2F8 E2F transcription factor 8 2 2
MIRT555020 RAB23 RAB23, member RAS oncogene family 2 2
MIRT560728 ZNF529 zinc finger protein 529 2 10
MIRT564890 YTHDF3 YTH N6-methyladenosine RNA binding protein 3 2 2
MIRT567327 HMGB1 high mobility group box 1 2 2
MIRT568035 CLIP4 CAP-Gly domain containing linker protein family member 4 2 2
MIRT574763 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT620811 SLC26A2 solute carrier family 26 member 2 2 2
MIRT622456 RNF19B ring finger protein 19B 2 2
MIRT636240 SIM1 single-minded family bHLH transcription factor 1 2 2
MIRT643231 MUC15 mucin 15, cell surface associated 2 2
MIRT646319 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT646674 CCDC69 coiled-coil domain containing 69 2 2
MIRT650043 VHL von Hippel-Lindau tumor suppressor 2 2
MIRT652533 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT663022 CD40LG CD40 ligand 2 2
MIRT667465 MAPK10 mitogen-activated protein kinase 10 2 2
MIRT668620 EEA1 early endosome antigen 1 2 2
MIRT675678 SLC35F5 solute carrier family 35 member F5 2 2
MIRT681814 N4BP2L2 NEDD4 binding protein 2 like 2 2 2
MIRT682674 CPM carboxypeptidase M 2 2
MIRT701447 NFIC nuclear factor I C 2 2
MIRT706222 C20orf144 chromosome 20 open reading frame 144 2 2
MIRT707510 PPP1R16B protein phosphatase 1 regulatory subunit 16B 2 2
MIRT710466 ASTN2 astrotactin 2 2 2
MIRT712957 SGCD sarcoglycan delta 2 2
MIRT723030 MYLIP myosin regulatory light chain interacting protein 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-3152-3p 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3152-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3152-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-miR-3152-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

Error report submission