miRTarBase - #MIRT523010


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pre-miRNA Information
pre-miRNA hsa-mir-4529   
Genomic Coordinates chr18: 55479221 - 55479298
Description Homo sapiens miR-4529 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4529-5p
Sequence 6| AGGCCAUCAGCAGUCCAAUGAA |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1325288049 1 dbSNP
rs1233088462 15 dbSNP
rs1324866273 19 dbSNP
Putative Targets

Gene Information
Gene Symbol IL6R   
Synonyms CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Description interleukin 6 receptor
Transcript NM_181359   
Other Transcripts NM_000565   
Expression
Putative miRNA Targets on IL6R
3'UTR of IL6R
(miRNA target sites are highlighted)		 
>IL6R|NM_181359|3'UTR
   1 AGGAAGGCAAGACAAGCATGCATCCGCCGTACTCTTTGGGGCAGCTGGTCCCGGAGAGGCCTCGACCCACCCCAGTGCTT
  81 GTTCCTCTCATCTCCCCACCGGTGTCCCCCAGCAGCCTGGGGTCTGACAATACCTCGAGCCACAACCGACCAGATGCCAG
 161 GGACCCACGGAGCCCTTATGACATCAGCAATACAGACTACTTCTTCCCCAGATAGCTGGCTGGGTGGCACCAGCAGCCTG
 241 GACCCTGTGGATGATAAAACACAAACGGGCTCAGCAAAAGATGCTTCTCACTGCCATGCCAGCTTATCTCAGGGGTGTGC
 321 GGCCTTTGGCTTCACGGAAGAGCCTTGCGGAAGGTTCTACGCCAGGGGAAAATCAGCCTGCTCCAGCTGTTCAGCTGGTT
 401 GAGGTTTCAAACCTCCCTTTCCAAATGCCCAGCTTAAAGGGGCTAGAGTGAACTTGGGCCACTGTGAAGAGAACCATATC
 481 AAGACTCTTTGGACACTCACACGGACACTCAAAAGCTGGGCAGGTTGGTGGGGGCCTCGGTGTGGAGAAGCGGCTGGCAG
 561 CCCACCCCTCAACACCTCTGCACAAGCTGCACCCTCAGGCAGGTGGGATGGATTTCCAGCCAAAGCCTCCTCCAGCCGCC
 641 ATGCTCCTGGCCCACTGCATCGTTTCATCTTCCAACTCAAACTCTTAAAACCCAAGTGCCTTAGCAAATTCTGTTTTTCT
 721 AGGCCTGGGGACGGCTTTTACTTAAACCGCCAAGGCTGGGGGAAGAAGCTCTCTCCTCCCTTTCTTCCCTACAGTTGAAA
 801 AACAGCTGAGGGTGAGTGGGTGAATAATACAGTATCTCAGGGCCTGGTCGTTTTCAACAGAATTATAATTAGTTCCTCAT
 881 TAGCATTTTGCTAAATGTGAATGATGATCCTAGGCATTTGCTGAATACAGAGGCAACTGCATTGGCTTTGGGTTGCAGGA
 961 CCTCAGGTGAGAAGCAGAGGAAGGAGAGGAGAGGGGCACAGGGTCTCTACCATCCCCTGTAGAGTGGGAGCTGAGTGGGG
1041 GATCACAGCCTCTGAAAACCAATGTTCTCTCTTCTCCACCTCCCACAAAGGAGAGCTAGCAGCAGGGAGGGCTTCTGCCA
1121 TTTCTGAGATCAAAACGGTTTTACTGCAGCTTTGTTTGTTGTCAGCTGAACCTGGGTAACTAGGGAAGATAATATTAAGG
1201 AAGACAATGTGAAAAGAAAAATGAGCCTGGCAAGAATGTGTTTAAACTTGGTTTTTAAAAAACTGCTGACTGTTTTCTCT
1281 TGAGAGGGTGGAATATCCAATATTCGCTGTGTCAGCATAGAAGTAACTTACTTAGGTGTGGGGGAAGCACCATAACTTTG
1361 TTTAGCCCAAAACCAAGTCAAGTGAAAAAGGAGGAAGAGAAAAAATATTTTCCTGCCAGGCATGGTGGCCCACGCACTTC
1441 GGGAGGTCGAGGCAGGAGGATCACTTGAGTCCAGAAGTTTGAGATCAGCCTGGGCAATGTGATAAAACCCCATCTCTACA
1521 AAAAGCATAAAAATTAGCCAAGTGTGGTAGAGTGTGCCTGAAGTCCCAGATACTTGGGGGGCTGAGGTGGGAGGATCTCT
1601 TGAGCCTGGGAGGTCAAGGCTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGTGAGACCC
1681 TGTCTCAAAAAAAGAAAAAGAAAAAGAAAAAATATTTTCCCTATTAGAGAAGAGATTGTGGTTTCATTCTGTATTTTGTT
1761 TTTGTCTTAAAAAGTGGAAAAATAGCCTGCCTCTTCTCTACTCTAGGGAAAAACCAGCGTGTGACTACTCCCCCAGGTGG
1841 TTATGGAGAGGGTGTCCGGTCCCTGTCCCAGTGCCGAGAAGGAAGCCTCCCACGACTGCCCGGCAGGGTCCTAGAAATTC
1921 CCCACCCTGAAAGCCCTGAGCTTTCTGCTATCAAAGAGGTTTTAAAAAAATCCCATTTAAAAAAAATCCCTTACCTCGGT
2001 GCCTTCCTCTTTTTATTTAGTTCCTTGAGTTGATTCAGCTCTGCAAGAATTGAAGCAGGACTAAATGTCTAGTTGTAACA
2081 CCATGATTAACCACTTCAGCTGACTTTTCTGTCCGAGCTTTGAAAATTCAGTGGTGTTAGTGGTTACCCAGTTAGCTCTC
2161 AAGTTATCAGGGTATTCCAGAGTGGGGATATGATTTAAATCAGCCGTGTAACCATGGACCCAATATTTACCAGACCACAA
2241 AACTTTTCTAATACTCTACCCTCTTAGAAAAACCACCACCATCACCAGACAGGTGCGAAAGGATGAAAGTGACCATGTTT
2321 TGTTTACGGTTTTCCAGGTTTAAGCTGTTACTGTCTTCAGTAAGCCGTGATTTTCATTGCTGGGCTTGTCTGTAGATTTT
2401 AGACCCTATTGCTGCTTGAGGCAACTCATCTTAGGTTGGCAAAAAGGCAGGATGGCCGGGCGCGGTGGCTCACGCCTGTA
2481 ATCCTAGCACTTTGGGAGGCCAAGGTGGGAGGATTGCTTGAGCTCAGGAGTTTGAGACCAACCTGGGTAACATAGTGAGA
2561 CACCATCTCTATTATGAACAATAACAGTTAAGAAAAAAAAAGGCAGGCAGGCGGTTATGGTGGTTCCCTCCCATCCCACC
2641 ACATAAAGTTTCTGAGACTTGAGAACAGCAAAATGCTGTTAAAGGGAAATATTAAGAATGAGAATCTGCAGTAAGGGTGA
2721 TTCTGTGCCCACAGTTCTTCAATTCTTTATACCGTTTTACCCACATGTGGTGTTACCAAAGCCGGGCAGAACCATGCTAG
2801 CGGAAGATGTGAAATCCAGATAGCTCATTATTGCCAAGAGCTAGGCAGCTTTGATCTCCAAATTGTTATTGCTTTCATTT
2881 TTATTGTAATGGAATTGCTTTGTTTTGTTTTTTTGTTTTTGTATTGAAGAGGGTTGTTTTCCCTTTATTTTTCATAAGCT
2961 AATGTAAATGAAGAAAAAATGTCTTCTCTGGGCTGTAGGCCTGGCTCAGCGTACACAGGTATACATCCTAAGCTCTCTAT
3041 GTTCTCTAATCTGTGGTGACTGAACATGTGTCTCAATGCACGGGGCATTTCTACCTGTGTTTCTGCAGCACCCCCACTGC
3121 CTTGAGTCCCCAGCAGTGCTGTTATTTGCCTAACACCTGTAGCCATCTGCCACGCAGCCAGACGTGAAACGCTGAGACAG
3201 AGACCATTTAGGTTAAATACGACAGCTTATCCTGCTGGGTGGGGAAAGTAAAAAATATGCTGGTTCAAGGCCTAAAGTAA
3281 AATGATCAATAATGTTTGTAGCATTAATGAAATATTTTCAAGAAATGTGTCCAGGGGTAGCACTGGCTATGTTGACGAGG
3361 CCTTTGGTAACTCAGAGAGCTCTTGGCCCTGATGGGGACTTGCCCTTACGCTTTCTTTATCAGGCTCTGAGTTCACACGG
3441 AGCCTCTGGCACTTCCCTGCTGTCTTGGGAGAAAGGAAACTGGTTGCCGCGGCAGGTTGTGGAATCTGTTGCTGGAACCA
3521 GGCTGGAAGCCCACCTGGTAGTGAACAGGGCCCAGTGGGGCAGGCTGGGCATGTTGTGGTCTATGGGTTTGTTTCCTGGA
3601 GAATGTTCAGGAATGTCTTCCCAGCTGCTTTGGTGCTGAGCTCTATTATCTCACAGCACGTCCAGAAGGCTAACCCAGGT
3681 GGGGAGGATGCTGACACCAGCTCCAGGTGGAGTTGGTGGTCTTAATTTGGAGATGCAGGGGCAACCTGTGACCCTTTGAG
3761 GCAAGAGCCCTGCACCCAGCTGTCCCGTGCAGCCGTGGGCAGGGGCTGCACACGGAGGGGCAGGCGGGCCAGTTCAGGGT
3841 CCGTGCCAGGCCCTCCTCAGTGCCCTGTGAAGGCCTCCTGTCCTCCGTGCGGCTGGGCACCAGCACCAGGGAGTTTCTAT
3921 GGCAACCTTAGTGATTATTAAGGAACACTGTCAGTTTTATGAACATATGCTCAAATGAAATTCTACTTTAGGAGGAAAGG
4001 ATTGGAACAGCATGTCACAAGGCTGTTAATTAACAGAGAGACCTTATTGGATGGAGATCACATCTGTTAAATAGAATACC
4081 TCAACTCTACGTTGTTTTCTTGGAGATAAATAATAGTTTCAAGTTTTTGTTTGTTTGTTTTACCTAATTACCTGAAAGCA
4161 AATACCAAAGGCTGATGTCTGTATATGGGGCAAAGGGTCAGTATATTTTTCAGTGTTTTTTTTTCTACCAGCTATTTTGC
4241 ATTTAAAGTGAACATTGTGTTTGGAATAAATACTCTTAAAAAATAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aagUAACC----UGACG-ACUACCGGa 5'
             :||||    |  ||  ||||||| 
Target 5' tagGTTGGCAAAAAGGCAGGATGGCCg 3'
 2432 - 2458 145.00 -15.60
2 
miRNA  3' aaGUAACCUGACG------ACUACCGGa 5'
            :|||   ||||      ||:||||| 
Target 5' aaTATTTTCCTGCCAGGCATGGTGGCCc 3'
 1404 - 1431 138.00 -15.10
3 
miRNA  3' aaGUAACCUGACGACUACCGGa 5'
            || ||  ||| ||| |||| 
Target 5' ctCAGTGCCCTG-TGAAGGCCt 3'
 3856 - 3876 131.00 -15.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1122644 161 ClinVar
783948 201 ClinVar
COSM3705024 6 COSMIC
COSM9152048 11 COSMIC
COSM6901248 12 COSMIC
COSM5341563 27 COSMIC
COSM7856193 29 COSMIC
COSM1210605 33 COSMIC
COSM9766881 35 COSMIC
COSM6019551 40 COSMIC
COSM8552993 49 COSMIC
COSM4692367 53 COSMIC
COSM8625022 64 COSMIC
COSM4022808 69 COSMIC
COSM4463319 95 COSMIC
COSM9663088 96 COSMIC
COSM4142762 133 COSMIC
COSM6121531 138 COSMIC
COSM82194 138 COSMIC
COSM5168204 145 COSMIC
COSM896611 146 COSMIC
COSM7954132 148 COSMIC
COSM6685439 168 COSMIC
COSM5843795 170 COSMIC
COSM9926420 175 COSMIC
COSM8381298 178 COSMIC
COSM4951910 180 COSMIC
COSM423991 183 COSMIC
COSM4186523 205 COSMIC
COSM6044703 210 COSMIC
COSN30185295 228 COSMIC
COSN30180871 254 COSMIC
COSN5732078 259 COSMIC
COSN26980393 268 COSMIC
COSN31603309 271 COSMIC
COSN30519584 285 COSMIC
COSN30110741 321 COSMIC
COSN30478989 324 COSMIC
COSN30478999 325 COSMIC
COSN31503583 329 COSMIC
COSN6507410 444 COSMIC
COSN20090365 465 COSMIC
COSN1407071 604 COSMIC
COSN25435478 631 COSMIC
COSN1089793 675 COSMIC
COSN31608978 861 COSMIC
COSN22926969 902 COSMIC
COSN21344897 911 COSMIC
COSN22007645 1307 COSMIC
COSN19716232 2033 COSMIC
COSN6003450 2124 COSMIC
COSN1089794 2197 COSMIC
COSN9363655 2359 COSMIC
COSN4900816 2486 COSMIC
COSN19585684 2621 COSMIC
COSN19484790 2915 COSMIC
COSN8320144 3182 COSMIC
COSN29154180 3245 COSMIC
COSN1407072 3304 COSMIC
COSN28221105 3417 COSMIC
COSN8643400 3622 COSMIC
COSN22270443 3800 COSMIC
COSN4744027 3891 COSMIC
COSN8320145 3892 COSMIC
COSN29999360 4083 COSMIC
COSN15860094 4092 COSMIC
rs2229238 256 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs767331184 4 dbSNP
rs1179625145 6 dbSNP
rs978023222 9 dbSNP
rs1360717962 11 dbSNP
rs775305856 14 dbSNP
rs1302604079 15 dbSNP
rs760368867 16 dbSNP
rs1398293656 19 dbSNP
rs763867407 22 dbSNP
rs150127972 26 dbSNP
rs907353552 27 dbSNP
rs149334407 29 dbSNP
rs764787666 30 dbSNP
rs1277848589 35 dbSNP
rs750995068 39 dbSNP
rs780683821 40 dbSNP
rs1054678099 46 dbSNP
rs1214944137 47 dbSNP
rs768405896 47 dbSNP
rs1484149205 48 dbSNP
rs747462813 51 dbSNP
rs142732420 53 dbSNP
rs146099074 54 dbSNP
rs748261127 64 dbSNP
rs1415420764 66 dbSNP
rs376291841 67 dbSNP
rs1432214451 68 dbSNP
rs1264270707 69 dbSNP
rs777795126 70 dbSNP
rs749338745 71 dbSNP
rs1487411118 74 dbSNP
rs1471126539 75 dbSNP
rs143810642 79 dbSNP
rs775278680 92 dbSNP
rs1445263609 93 dbSNP
rs776495733 99 dbSNP
rs199661599 101 dbSNP
rs973125399 102 dbSNP
rs768275273 104 dbSNP
rs761872691 106 dbSNP
rs868400405 106 dbSNP
rs150069111 109 dbSNP
rs761327396 112 dbSNP
rs764951367 114 dbSNP
rs570211746 117 dbSNP
rs983176795 122 dbSNP
rs762537792 133 dbSNP
rs767057760 135 dbSNP
rs770082460 136 dbSNP
rs751945943 137 dbSNP
rs755384864 138 dbSNP
rs1177562623 140 dbSNP
rs1423409957 141 dbSNP
rs781363874 142 dbSNP
rs752994852 148 dbSNP
rs756372545 149 dbSNP
rs777953068 150 dbSNP
rs1291887163 152 dbSNP
rs1369955192 159 dbSNP
rs749430277 160 dbSNP
rs142713546 161 dbSNP
rs780052087 169 dbSNP
rs1220388798 170 dbSNP
rs974555512 173 dbSNP
rs201626760 174 dbSNP
rs1218689744 175 dbSNP
rs746869010 179 dbSNP
rs768524019 180 dbSNP
rs773373443 182 dbSNP
rs776325795 183 dbSNP
rs761677464 190 dbSNP
rs1431089810 191 dbSNP
rs1382538217 192 dbSNP
rs1188676544 196 dbSNP
rs897620451 196 dbSNP
rs769627352 197 dbSNP
rs772992976 200 dbSNP
rs2228147 201 dbSNP
rs765750844 203 dbSNP
rs539906802 207 dbSNP
rs891766500 212 dbSNP
rs946147738 215 dbSNP
rs1045820749 224 dbSNP
rs759921343 234 dbSNP
rs768041705 239 dbSNP
rs559033680 240 dbSNP
rs1034925604 241 dbSNP
rs1018599433 245 dbSNP
rs1378308031 247 dbSNP
rs753055692 250 dbSNP
rs564815270 252 dbSNP
rs778039275 255 dbSNP
rs2229238 256 dbSNP
rs924780632 257 dbSNP
rs1321955729 258 dbSNP
rs181169482 260 dbSNP
rs778814658 267 dbSNP
rs562546238 268 dbSNP
rs1415905664 269 dbSNP
rs950407553 270 dbSNP
rs983103282 288 dbSNP
rs1227017605 292 dbSNP
rs1018729231 299 dbSNP
rs1180135028 300 dbSNP
rs948935081 302 dbSNP
rs965783576 313 dbSNP
rs148018129 321 dbSNP
rs1225399297 322 dbSNP
rs974581622 336 dbSNP
rs921720989 337 dbSNP
rs548504207 338 dbSNP
rs566640792 349 dbSNP
rs935951408 350 dbSNP
rs28730737 355 dbSNP
rs1378015832 360 dbSNP
rs1303114333 361 dbSNP
rs1365241901 362 dbSNP
rs897668443 371 dbSNP
rs186087257 372 dbSNP
rs1430350466 379 dbSNP
rs1391870233 384 dbSNP
rs1162459048 396 dbSNP
rs1423269872 420 dbSNP
rs1048863052 424 dbSNP
rs1183886208 425 dbSNP
rs1385647684 428 dbSNP
rs1251560129 429 dbSNP
rs749223780 433 dbSNP
rs1426261842 434 dbSNP
rs570835300 441 dbSNP
rs372345902 442 dbSNP
rs556274427 443 dbSNP
rs7514452 444 dbSNP
rs1348181596 449 dbSNP
rs150565185 468 dbSNP
rs1410162801 472 dbSNP
rs1398577306 477 dbSNP
rs1291765185 479 dbSNP
rs1457317496 486 dbSNP
rs1369185963 490 dbSNP
rs1166932339 493 dbSNP
rs1471735319 494 dbSNP
rs114445392 503 dbSNP
rs1337549122 505 dbSNP
rs1183378022 506 dbSNP
rs1265665528 529 dbSNP
rs1446113538 539 dbSNP
rs1055972630 540 dbSNP
rs572441011 541 dbSNP
rs1306668689 552 dbSNP
rs1265532300 553 dbSNP
rs1234520651 560 dbSNP
rs957091110 566 dbSNP
rs990343216 571 dbSNP
rs1228600902 573 dbSNP
rs898637359 582 dbSNP
rs1023128789 584 dbSNP
rs1248587148 585 dbSNP
rs970335428 587 dbSNP
rs375558987 597 dbSNP
rs1339289602 601 dbSNP
rs1328040931 613 dbSNP
rs545965886 619 dbSNP
rs1047792963 620 dbSNP
rs1195943336 628 dbSNP
rs200977651 632 dbSNP
rs887339496 634 dbSNP
rs188999578 638 dbSNP
rs576857204 647 dbSNP
rs1182619295 649 dbSNP
rs1243329976 651 dbSNP
rs1434262010 662 dbSNP
rs1446262868 663 dbSNP
rs973249069 664 dbSNP
rs920037178 668 dbSNP
rs1463201899 670 dbSNP
rs1266905863 682 dbSNP
rs931384942 683 dbSNP
rs1372487797 692 dbSNP
rs965788485 697 dbSNP
rs544308264 703 dbSNP
rs996304911 712 dbSNP
rs1305595956 717 dbSNP
rs562300916 723 dbSNP
rs555545695 725 dbSNP
rs1028837666 728 dbSNP
rs888947865 731 dbSNP
rs371605198 732 dbSNP
rs763582991 733 dbSNP
rs529734559 734 dbSNP
rs1400259769 740 dbSNP
rs1172395496 741 dbSNP
rs943293808 742 dbSNP
rs1468263414 749 dbSNP
rs771213605 750 dbSNP
rs1449391933 756 dbSNP
rs542107810 759 dbSNP
rs998555763 771 dbSNP
rs180853955 772 dbSNP
rs1199501592 773 dbSNP
rs73016204 774 dbSNP
rs1282190816 789 dbSNP
rs892922848 791 dbSNP
rs552083218 794 dbSNP
rs574198524 796 dbSNP
rs1138004 798 dbSNP
rs35697299 798 dbSNP
rs570665321 800 dbSNP
rs1432931949 805 dbSNP
rs1454971033 809 dbSNP
rs1293877353 813 dbSNP
rs531671897 815 dbSNP
rs970181557 817 dbSNP
rs1228809696 822 dbSNP
rs1429677552 823 dbSNP
rs928602574 825 dbSNP
rs1391280097 827 dbSNP
rs550250571 828 dbSNP
rs1476135932 831 dbSNP
rs1253547061 834 dbSNP
rs1138006 837 dbSNP
rs1342298498 845 dbSNP
rs1186478275 846 dbSNP
rs759969926 851 dbSNP
rs143508443 862 dbSNP
rs561204504 867 dbSNP
rs1202682573 873 dbSNP
rs1482707543 877 dbSNP
rs1275211706 890 dbSNP
rs56405911 892 dbSNP
rs1056255621 910 dbSNP
rs1283670290 911 dbSNP
rs535441734 914 dbSNP
rs765749996 921 dbSNP
rs753220635 926 dbSNP
rs1263422293 930 dbSNP
rs972788472 939 dbSNP
rs1306596112 942 dbSNP
rs931497616 946 dbSNP
rs1047225548 957 dbSNP
rs1404087565 958 dbSNP
rs1411066213 964 dbSNP
rs553779734 972 dbSNP
rs1162061921 980 dbSNP
rs1186509382 992 dbSNP
rs887392868 996 dbSNP
rs762278989 997 dbSNP
rs1475335034 1002 dbSNP
rs1008444480 1003 dbSNP
rs763325288 1011 dbSNP
rs1179782391 1017 dbSNP
rs1428847579 1019 dbSNP
rs575032850 1032 dbSNP
rs566031026 1037 dbSNP
rs952839374 1037 dbSNP
rs764680976 1038 dbSNP
rs35013949 1040 dbSNP
rs1214355136 1042 dbSNP
rs1375832534 1050 dbSNP
rs1479527175 1065 dbSNP
rs1286745250 1070 dbSNP
rs1175784988 1080 dbSNP
rs910397637 1094 dbSNP
rs1281620518 1097 dbSNP
rs1471081446 1103 dbSNP
rs995842305 1112 dbSNP
rs1322344464 1114 dbSNP
rs559125205 1121 dbSNP
rs957140020 1126 dbSNP
rs1011857283 1127 dbSNP
rs1020039709 1128 dbSNP
rs967272523 1129 dbSNP
rs1298423874 1131 dbSNP
rs1408514486 1137 dbSNP
rs923242949 1142 dbSNP
rs1344146344 1148 dbSNP
rs1477003714 1159 dbSNP
rs934562698 1160 dbSNP
rs1222428669 1161 dbSNP
rs1194161155 1165 dbSNP
rs1469908217 1185 dbSNP
rs981303123 1186 dbSNP
rs1283357816 1189 dbSNP
rs558030327 1192 dbSNP
rs140017311 1196 dbSNP
rs1213245540 1197 dbSNP
rs1259742464 1201 dbSNP
rs1486096650 1202 dbSNP
rs1317679472 1215 dbSNP
rs958729291 1225 dbSNP
rs1286783387 1226 dbSNP
rs1052807717 1227 dbSNP
rs528173790 1236 dbSNP
rs4072391 1240 dbSNP
rs1372626035 1241 dbSNP
rs920044790 1246 dbSNP
rs556237141 1247 dbSNP
rs1345349145 1248 dbSNP
rs1199976948 1257 dbSNP
rs755871919 1261 dbSNP
rs1412592120 1264 dbSNP
rs1424170476 1268 dbSNP
rs779785489 1272 dbSNP
rs1430086960 1286 dbSNP
rs143633779 1288 dbSNP
rs1003068589 1299 dbSNP
rs749129614 1300 dbSNP
rs768418348 1301 dbSNP
rs1047685315 1306 dbSNP
rs908687486 1307 dbSNP
rs1312022144 1326 dbSNP
rs145758823 1334 dbSNP
rs1157233988 1337 dbSNP
rs1294774362 1339 dbSNP
rs560236383 1341 dbSNP
rs879111697 1344 dbSNP
rs931677631 1352 dbSNP
rs1362009712 1362 dbSNP
rs187407525 1368 dbSNP
rs1445349536 1370 dbSNP
rs778911423 1374 dbSNP
rs1011288210 1375 dbSNP
rs1168064764 1392 dbSNP
rs1429250281 1411 dbSNP
rs1421708277 1414 dbSNP
rs1180409929 1423 dbSNP
rs1138007 1427 dbSNP
rs190944109 1434 dbSNP
rs985527150 1435 dbSNP
rs902997872 1436 dbSNP
rs1002650401 1441 dbSNP
rs1213384799 1442 dbSNP
rs1035595828 1449 dbSNP
rs1274612359 1450 dbSNP
rs868482951 1452 dbSNP
rs564079019 1461 dbSNP
rs1228753392 1464 dbSNP
rs148955274 1474 dbSNP
rs549744082 1478 dbSNP
rs564994489 1482 dbSNP
rs1354351543 1505 dbSNP
rs1313291598 1511 dbSNP
rs1416339727 1517 dbSNP
rs1305917057 1520 dbSNP
rs1368449721 1521 dbSNP
rs759882086 1528 dbSNP
rs1462433914 1530 dbSNP
rs1374922919 1535 dbSNP
rs1052988855 1542 dbSNP
rs1423466970 1551 dbSNP
rs914255383 1559 dbSNP
rs1190541812 1560 dbSNP
rs982834912 1561 dbSNP
rs1471837009 1570 dbSNP
rs1251538473 1571 dbSNP
rs1196943073 1573 dbSNP
rs1481870971 1575 dbSNP
rs908614301 1578 dbSNP
rs1333729211 1582 dbSNP
rs944209647 1588 dbSNP
rs866133323 1594 dbSNP
rs1234717939 1610 dbSNP
rs1241005968 1613 dbSNP
rs921547381 1619 dbSNP
rs142901087 1627 dbSNP
rs1050514577 1629 dbSNP
rs905642800 1630 dbSNP
rs1460943275 1632 dbSNP
rs892780880 1633 dbSNP
rs1395267683 1641 dbSNP
rs868239881 1648 dbSNP
rs1455829922 1650 dbSNP
rs1411704834 1652 dbSNP
rs1041477781 1655 dbSNP
rs1175531613 1663 dbSNP
rs1421427477 1665 dbSNP
rs1265822238 1667 dbSNP
rs1191098893 1670 dbSNP
rs902924432 1679 dbSNP
rs529394524 1682 dbSNP
rs1215244076 1689 dbSNP
rs897276605 1689 dbSNP
rs530689821 1694 dbSNP
rs41310931 1698 dbSNP
rs1424382616 1703 dbSNP
rs888679665 1703 dbSNP
rs1164820908 1705 dbSNP
rs1440074057 1706 dbSNP
rs1371890464 1712 dbSNP
rs1006874562 1715 dbSNP
rs1012797603 1722 dbSNP
rs1367981361 1723 dbSNP
rs1439467363 1729 dbSNP
rs1384473004 1738 dbSNP
rs151093263 1741 dbSNP
rs1455717104 1746 dbSNP
rs1297103496 1747 dbSNP
rs1376254139 1752 dbSNP
rs1173637088 1754 dbSNP
rs1373342616 1759 dbSNP
rs965527573 1763 dbSNP
rs1027412331 1771 dbSNP
rs1194884430 1778 dbSNP
rs977200725 1797 dbSNP
rs1260549490 1805 dbSNP
rs1205333842 1816 dbSNP
rs1030170214 1820 dbSNP
rs1254011178 1822 dbSNP
rs35470849 1830 dbSNP
rs1233490083 1831 dbSNP
rs114564798 1834 dbSNP
rs1432923899 1836 dbSNP
rs536201124 1841 dbSNP
rs1015725324 1845 dbSNP
rs558449209 1846 dbSNP
rs1319272419 1850 dbSNP
rs1384132026 1854 dbSNP
rs914517992 1857 dbSNP
rs1246395682 1858 dbSNP
rs947275292 1859 dbSNP
rs570113126 1869 dbSNP
rs1175002160 1872 dbSNP
rs1202601778 1876 dbSNP
rs537632902 1877 dbSNP
rs1448310615 1887 dbSNP
rs1253818878 1888 dbSNP
rs535611420 1892 dbSNP
rs1480965487 1894 dbSNP
rs142609993 1895 dbSNP
rs1226040427 1903 dbSNP
rs1338901428 1906 dbSNP
rs965443660 1910 dbSNP
rs1057251498 1918 dbSNP
rs1241499452 1922 dbSNP
rs113977424 1926 dbSNP
rs1415733937 1927 dbSNP
rs921400711 1929 dbSNP
rs1306765733 1934 dbSNP
rs1184581548 1936 dbSNP
rs1395157757 1937 dbSNP
rs1167920620 1938 dbSNP
rs1476205382 1948 dbSNP
rs954462806 1957 dbSNP
rs1186754500 1960 dbSNP
rs556779665 1960 dbSNP
rs1018276534 1964 dbSNP
rs1437103696 1964 dbSNP
rs989722692 1964 dbSNP
rs915466968 1965 dbSNP
rs901132994 1970 dbSNP
rs1354538935 1971 dbSNP
rs1354636436 1973 dbSNP
rs1292963158 1976 dbSNP
rs1031482355 1979 dbSNP
rs879898081 1979 dbSNP
rs574579254 1980 dbSNP
rs796397215 1986 dbSNP
rs1041363189 1989 dbSNP
rs956796344 1992 dbSNP
rs1328968979 1993 dbSNP
rs924399613 1998 dbSNP
rs938400498 1999 dbSNP
rs968662480 2003 dbSNP
rs1419778455 2004 dbSNP
rs926988124 2005 dbSNP
rs752177279 2012 dbSNP
rs1469592367 2014 dbSNP
rs761064510 2015 dbSNP
rs894279883 2021 dbSNP
rs1183880258 2030 dbSNP
rs878950485 2032 dbSNP
rs938319364 2034 dbSNP
rs1013152000 2035 dbSNP
rs1359522341 2043 dbSNP
rs1213927805 2051 dbSNP
rs1337136161 2060 dbSNP
rs1282630048 2063 dbSNP
rs1223524023 2068 dbSNP
rs1351823621 2072 dbSNP
rs1048329394 2085 dbSNP
rs888357571 2093 dbSNP
rs1004248730 2095 dbSNP
rs1434937205 2097 dbSNP
rs1015568211 2103 dbSNP
rs1368219638 2107 dbSNP
rs992487906 2110 dbSNP
rs1308199674 2111 dbSNP
rs541985083 2115 dbSNP
rs998245474 2116 dbSNP
rs1028924960 2129 dbSNP
rs1408408331 2134 dbSNP
rs761216806 2138 dbSNP
rs954267993 2147 dbSNP
rs1252452889 2166 dbSNP
rs1461036172 2173 dbSNP
rs990038139 2178 dbSNP
rs1240625891 2183 dbSNP
rs1239594413 2185 dbSNP
rs1169578943 2187 dbSNP
rs1474604082 2188 dbSNP
rs1215291633 2191 dbSNP
rs183148051 2200 dbSNP
rs888575480 2206 dbSNP
rs767063254 2207 dbSNP
rs749966968 2216 dbSNP
rs1302102321 2220 dbSNP
rs4379670 2225 dbSNP
rs1173615120 2232 dbSNP
rs1286801536 2233 dbSNP
rs1429589359 2237 dbSNP
rs901191411 2243 dbSNP
rs143915141 2244 dbSNP
rs768713015 2244 dbSNP
rs1469997435 2245 dbSNP
rs1338226248 2251 dbSNP
rs1343234156 2255 dbSNP
rs879035888 2257 dbSNP
rs1432815003 2265 dbSNP
rs1394347902 2271 dbSNP
rs1174156869 2274 dbSNP
rs1429735076 2279 dbSNP
rs1052434072 2293 dbSNP
rs892589581 2297 dbSNP
rs1186203961 2304 dbSNP
rs1486283073 2306 dbSNP
rs1270752756 2314 dbSNP
rs1010992929 2317 dbSNP
rs1363977547 2327 dbSNP
rs924240039 2328 dbSNP
rs1220619917 2329 dbSNP
rs1021473443 2332 dbSNP
rs968507642 2337 dbSNP
rs545751407 2351 dbSNP
rs1034658750 2355 dbSNP
rs1167919108 2358 dbSNP
rs377649087 2367 dbSNP
rs370141314 2368 dbSNP
rs1280951271 2389 dbSNP
rs1374587882 2390 dbSNP
rs1445676886 2396 dbSNP
rs560844168 2397 dbSNP
rs918254133 2405 dbSNP
rs1215490972 2408 dbSNP
rs1243256285 2409 dbSNP
rs951134548 2410 dbSNP
rs1169746706 2412 dbSNP
rs1429374255 2414 dbSNP
rs867560924 2415 dbSNP
rs983800898 2418 dbSNP
rs73016210 2422 dbSNP
rs1197804435 2439 dbSNP
rs1475110631 2441 dbSNP
rs1258655148 2448 dbSNP
rs1213718102 2458 dbSNP
rs576287294 2459 dbSNP
rs915627072 2461 dbSNP
rs942847955 2462 dbSNP
rs115361002 2463 dbSNP
rs561589436 2464 dbSNP
rs1480447978 2465 dbSNP
rs1048695540 2468 dbSNP
rs888376643 2472 dbSNP
rs1004091889 2474 dbSNP
rs1405323279 2475 dbSNP
rs1293616971 2502 dbSNP
rs529309464 2504 dbSNP
rs778700000 2508 dbSNP
rs1399958620 2513 dbSNP
rs1297704221 2515 dbSNP
rs1462604309 2519 dbSNP
rs922875497 2526 dbSNP
rs1163137927 2538 dbSNP
rs1346675900 2547 dbSNP
rs1419051426 2572 dbSNP
rs1190435550 2580 dbSNP
rs934253083 2582 dbSNP
rs1250496888 2593 dbSNP
rs1480709683 2593 dbSNP
rs901147066 2595 dbSNP
rs1052903611 2599 dbSNP
rs1211455095 2600 dbSNP
rs569016998 2602 dbSNP
rs547490952 2612 dbSNP
rs1011005866 2613 dbSNP
rs146898022 2614 dbSNP
rs954270127 2620 dbSNP
rs1391896355 2621 dbSNP
rs138882639 2622 dbSNP
rs533380847 2623 dbSNP
rs1001801774 2646 dbSNP
rs1440455324 2647 dbSNP
rs777962053 2651 dbSNP
rs1348791735 2656 dbSNP
rs1022852652 2665 dbSNP
rs1452129522 2667 dbSNP
rs1363576274 2681 dbSNP
rs1421338111 2687 dbSNP
rs551516989 2687 dbSNP
rs570305162 2700 dbSNP
rs1239469108 2701 dbSNP
rs537388639 2703 dbSNP
rs978290745 2705 dbSNP
rs960267021 2712 dbSNP
rs1211231896 2721 dbSNP
rs1356225719 2731 dbSNP
rs1014130775 2733 dbSNP
rs1259919776 2738 dbSNP
rs1220927149 2744 dbSNP
rs1025272000 2748 dbSNP
rs1355685725 2750 dbSNP
rs12566788 2751 dbSNP
rs1301384880 2754 dbSNP
rs1268745618 2755 dbSNP
rs951022391 2763 dbSNP
rs1380727607 2764 dbSNP
rs983853238 2764 dbSNP
rs1384715295 2765 dbSNP
rs1289748732 2766 dbSNP
rs1490385666 2771 dbSNP
rs1035221430 2772 dbSNP
rs1200360993 2784 dbSNP
rs959722500 2785 dbSNP
rs549588558 2791 dbSNP
rs567867686 2793 dbSNP
rs915696873 2798 dbSNP
rs1453312847 2817 dbSNP
rs1377693810 2821 dbSNP
rs1200631516 2825 dbSNP
rs1426311033 2827 dbSNP
rs963752840 2833 dbSNP
rs948438696 2837 dbSNP
rs983971723 2838 dbSNP
rs1205465547 2850 dbSNP
rs866428362 2852 dbSNP
rs1278150828 2860 dbSNP
rs78795257 2860 dbSNP
rs553926211 2866 dbSNP
rs1355899034 2870 dbSNP
rs939930275 2886 dbSNP
rs1210063305 2888 dbSNP
rs1158731048 2898 dbSNP
rs1381965660 2899 dbSNP
rs922792165 2901 dbSNP
rs1036981826 2903 dbSNP
rs1326033857 2903 dbSNP
rs1422472795 2904 dbSNP
rs1402300414 2907 dbSNP
rs1435870394 2908 dbSNP
rs143711852 2908 dbSNP
rs185963893 2908 dbSNP
rs934240530 2908 dbSNP
rs934048725 2916 dbSNP
rs913919226 2921 dbSNP
rs1162899299 2923 dbSNP
rs946679030 2929 dbSNP
rs1387483412 2937 dbSNP
rs1372097969 2948 dbSNP
rs868431587 2954 dbSNP
rs1193890176 2958 dbSNP
rs1043729933 2960 dbSNP
rs41308415 2964 dbSNP
rs555798357 2977 dbSNP
rs889886346 2989 dbSNP
rs938104886 2990 dbSNP
rs1280862695 2996 dbSNP
rs1194101287 2999 dbSNP
rs1011370332 3002 dbSNP
rs1333985909 3011 dbSNP
rs1056035629 3012 dbSNP
rs1293005249 3013 dbSNP
rs1415944384 3019 dbSNP
rs895612836 3020 dbSNP
rs1407749990 3036 dbSNP
rs1022479752 3038 dbSNP
rs745971543 3039 dbSNP
rs999629669 3040 dbSNP
rs1025492255 3041 dbSNP
rs373752557 3045 dbSNP
rs1163890207 3066 dbSNP
rs960936772 3068 dbSNP
rs767631680 3071 dbSNP
rs576277808 3082 dbSNP
rs1016547883 3083 dbSNP
rs1270290871 3085 dbSNP
rs200729727 3096 dbSNP
rs964175265 3098 dbSNP
rs1332868606 3114 dbSNP
rs1023012852 3125 dbSNP
rs112227838 3132 dbSNP
rs796465101 3141 dbSNP
rs1234236257 3150 dbSNP
rs112947886 3155 dbSNP
rs1278359747 3157 dbSNP
rs543363985 3170 dbSNP
rs1442597599 3171 dbSNP
rs190336181 3174 dbSNP
rs984246256 3175 dbSNP
rs1448571514 3176 dbSNP
rs955540692 3184 dbSNP
rs1182735214 3187 dbSNP
rs909621767 3191 dbSNP
rs939861817 3193 dbSNP
rs972560256 3205 dbSNP
rs922549302 3221 dbSNP
rs573524885 3222 dbSNP
rs1381008178 3224 dbSNP
rs541095733 3230 dbSNP
rs879163301 3232 dbSNP
rs1180547243 3244 dbSNP
rs1394442858 3245 dbSNP
rs1467331029 3250 dbSNP
rs979465444 3250 dbSNP
rs1409408929 3251 dbSNP
rs1222575653 3257 dbSNP
rs113444481 3259 dbSNP
rs1282520030 3260 dbSNP
rs1223715972 3262 dbSNP
rs1351975826 3276 dbSNP
rs1309378399 3281 dbSNP
rs1241746796 3284 dbSNP
rs116299819 3286 dbSNP
rs1324883664 3292 dbSNP
rs551747869 3295 dbSNP
rs1351419803 3298 dbSNP
rs1451004486 3300 dbSNP
rs946835735 3302 dbSNP
rs1361038841 3303 dbSNP
rs182789081 3309 dbSNP
rs895657190 3311 dbSNP
rs1394541746 3320 dbSNP
rs558273465 3334 dbSNP
rs1479090032 3345 dbSNP
rs1240748226 3353 dbSNP
rs1247655528 3357 dbSNP
rs141113814 3358 dbSNP
rs887060578 3362 dbSNP
rs999681870 3381 dbSNP
rs750356338 3394 dbSNP
rs1035115851 3396 dbSNP
rs1345193010 3397 dbSNP
rs1005423821 3399 dbSNP
rs1219456191 3407 dbSNP
rs1369238448 3408 dbSNP
rs896742927 3410 dbSNP
rs1340866174 3411 dbSNP
rs1459695315 3411 dbSNP
rs1202568704 3413 dbSNP
rs1243541742 3414 dbSNP
rs899464263 3420 dbSNP
rs997015730 3422 dbSNP
rs1374926635 3423 dbSNP
rs1029393202 3426 dbSNP
rs1416401223 3431 dbSNP
rs1417696692 3435 dbSNP
rs1425281321 3437 dbSNP
rs955283657 3439 dbSNP
rs549700993 3440 dbSNP
rs567831295 3444 dbSNP
rs1021129613 3450 dbSNP
rs1254936975 3456 dbSNP
rs749612665 3457 dbSNP
rs1012888462 3458 dbSNP
rs1270500039 3460 dbSNP
rs1475152701 3461 dbSNP
rs1340906509 3470 dbSNP
rs879085711 3487 dbSNP
rs769123245 3489 dbSNP
rs774699500 3490 dbSNP
rs77157934 3491 dbSNP
rs1303335865 3492 dbSNP
rs1450342659 3516 dbSNP
rs992549935 3531 dbSNP
rs1170081374 3556 dbSNP
rs554788859 3560 dbSNP
rs779674417 3566 dbSNP
rs929383598 3572 dbSNP
rs1403396636 3574 dbSNP
rs1257547614 3587 dbSNP
rs1184080527 3593 dbSNP
rs575066163 3600 dbSNP
rs908344525 3606 dbSNP
rs1318118439 3608 dbSNP
rs1259773860 3616 dbSNP
rs796484366 3621 dbSNP
rs565765659 3632 dbSNP
rs879007656 3646 dbSNP
rs1313433666 3660 dbSNP
rs192498214 3661 dbSNP
rs972571650 3662 dbSNP
rs899517068 3663 dbSNP
rs1447837424 3668 dbSNP
rs1251913679 3675 dbSNP
rs1402668893 3682 dbSNP
rs868735004 3698 dbSNP
rs1279546658 3699 dbSNP
rs1324113478 3705 dbSNP
rs922390820 3707 dbSNP
rs1369408924 3708 dbSNP
rs955336137 3714 dbSNP
rs1320725203 3717 dbSNP
rs1167602897 3726 dbSNP
rs1417778739 3728 dbSNP
rs1405200613 3735 dbSNP
rs1177413245 3740 dbSNP
rs1457802190 3742 dbSNP
rs1051190292 3747 dbSNP
rs985752789 3755 dbSNP
rs557697098 3757 dbSNP
rs1488068403 3761 dbSNP
rs1009280235 3766 dbSNP
rs1484134147 3767 dbSNP
rs1315015591 3769 dbSNP
rs1203133520 3771 dbSNP
rs946745251 3778 dbSNP
rs968177859 3782 dbSNP
rs1301611173 3784 dbSNP
rs1043699266 3787 dbSNP
rs924035373 3788 dbSNP
rs575952374 3796 dbSNP
rs1195687933 3797 dbSNP
rs1425904867 3803 dbSNP
rs1452285165 3807 dbSNP
rs1056573910 3812 dbSNP
rs536922359 3814 dbSNP
rs778521867 3815 dbSNP
rs1045748508 3817 dbSNP
rs1467955341 3819 dbSNP
rs754703988 3826 dbSNP
rs1157186391 3827 dbSNP
rs1005259301 3841 dbSNP
rs555259878 3842 dbSNP
rs1401158126 3843 dbSNP
rs3828078 3844 dbSNP
rs571968471 3852 dbSNP
rs765116321 3853 dbSNP
rs150298365 3862 dbSNP
rs955414864 3866 dbSNP
rs772247141 3874 dbSNP
rs941176759 3877 dbSNP
rs1303646887 3883 dbSNP
rs552793610 3885 dbSNP
rs752470908 3886 dbSNP
rs911162457 3887 dbSNP
rs578041232 3888 dbSNP
rs979404402 3891 dbSNP
rs923919008 3892 dbSNP
rs879072325 3893 dbSNP
rs1050784157 3894 dbSNP
rs1009330886 3904 dbSNP
rs1200513524 3917 dbSNP
rs182848885 3918 dbSNP
rs935428558 3920 dbSNP
rs1194323994 3923 dbSNP
rs563651604 3927 dbSNP
rs903586956 3932 dbSNP
rs1199986431 3935 dbSNP
rs1001061988 3939 dbSNP
rs1258048999 3945 dbSNP
rs1034253650 3950 dbSNP
rs959688130 3953 dbSNP
rs1435130547 3966 dbSNP
rs917988648 3967 dbSNP
rs1157118294 3983 dbSNP
rs1402422430 3983 dbSNP
rs1014216125 3988 dbSNP
rs1024984569 3990 dbSNP
rs948262084 4003 dbSNP
rs1174033099 4026 dbSNP
rs777870186 4026 dbSNP
rs983520986 4035 dbSNP
rs745879148 4043 dbSNP
rs909326676 4044 dbSNP
rs374321714 4048 dbSNP
rs530832272 4067 dbSNP
rs1235715859 4068 dbSNP
rs1186737698 4070 dbSNP
rs1443146002 4074 dbSNP
rs1258272873 4080 dbSNP
rs1194309463 4086 dbSNP
rs973968669 4088 dbSNP
rs1423511837 4089 dbSNP
rs921056449 4091 dbSNP
rs1220889428 4092 dbSNP
rs543308553 4098 dbSNP
rs1006440766 4111 dbSNP
rs1369027698 4114 dbSNP
rs187874068 4125 dbSNP
rs142187015 4126 dbSNP
rs371280903 4126 dbSNP
rs552910322 4138 dbSNP
rs993822439 4146 dbSNP
rs1444147740 4147 dbSNP
rs780127494 4153 dbSNP
rs1331587522 4155 dbSNP
rs747720401 4155 dbSNP
rs1242023205 4166 dbSNP
rs1411354596 4167 dbSNP
rs368278446 4178 dbSNP
rs912248620 4192 dbSNP
rs749573918 4194 dbSNP
rs1176812446 4201 dbSNP
rs1439130261 4215 dbSNP
rs11292096 4216 dbSNP
rs1239067543 4216 dbSNP
rs1450310444 4216 dbSNP
rs397764790 4216 dbSNP
rs398074318 4216 dbSNP
rs903637831 4221 dbSNP
rs1007142272 4225 dbSNP
rs1358639016 4225 dbSNP
rs936414846 4227 dbSNP
rs1055302130 4229 dbSNP
rs137962384 4256 dbSNP
rs774729477 4259 dbSNP
rs1025624534 4271 dbSNP
rs1448451201 4273 dbSNP
rs1347916981 4275 dbSNP
rs192354284 4276 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3570.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aaguaaccugacgaCUACCGGa 5'
                        ||||||| 
Target 5' --------------GAUGGCCg 3'
 		1 - 8
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM4903825
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / PID14_NS
Location of target site NM_000565 | 3UTR | AGGUUGGCAAAAAGGCAGGAUGGCCGGGCGCGGUGGCUCACGCCUGUAAUCCUAGCACUUUGGGAGGCCAAGGUGGGAGGAUUGCUUGAGCUCAGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161237
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000344086.4 | 3UTR | GAUGGCCGGGCGCGGUGGCUCACGCCU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
57 hsa-miR-4529-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT226211 TMEM64 transmembrane protein 64 2 2
MIRT241576 LAMC1 laminin subunit gamma 1 2 8
MIRT311423 LMNB1 lamin B1 2 2
MIRT458476 RMI1 RecQ mediated genome instability 1 2 10
MIRT476949 FAM83G family with sequence similarity 83 member G 2 2
MIRT480886 BCL9L B-cell CLL/lymphoma 9 like 2 2
MIRT492825 NXN nucleoredoxin 2 4
MIRT495860 CLCN6 chloride voltage-gated channel 6 2 2
MIRT495919 FBXO41 F-box protein 41 2 2
MIRT497150 PRDM15 PR/SET domain 15 2 2
MIRT498695 LYRM2 LYR motif containing 2 2 4
MIRT499954 ABI2 abl interactor 2 2 2
MIRT501309 RPS21 ribosomal protein S21 2 2
MIRT505941 RAP2C RAP2C, member of RAS oncogene family 2 4
MIRT508422 SFTPB surfactant protein B 2 2
MIRT510705 SREK1IP1 SREK1 interacting protein 1 2 6
MIRT513225 RYK receptor-like tyrosine kinase 2 2
MIRT513775 PER1 period circadian clock 1 2 6
MIRT514948 CD36 CD36 molecule 2 2
MIRT515902 AGTPBP1 ATP/GTP binding protein 1 2 2
MIRT516066 RAB42 RAB42, member RAS oncogene family 2 2
MIRT523010 IL6R interleukin 6 receptor 2 2
MIRT525065 FRK fyn related Src family tyrosine kinase 2 2
MIRT530304 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT530445 SULT1B1 sulfotransferase family 1B member 1 2 2
MIRT532421 ITFG2 integrin alpha FG-GAP repeat containing 2 2 2
MIRT532626 PHF5A PHD finger protein 5A 2 2
MIRT535128 PLK2 polo like kinase 2 2 2
MIRT539608 SHISA9 shisa family member 9 2 2
MIRT539640 BUB1 BUB1 mitotic checkpoint serine/threonine kinase 2 2
MIRT540213 RAB32 RAB32, member RAS oncogene family 2 2
MIRT540333 OPHN1 oligophrenin 1 2 2
MIRT544350 EGLN1 egl-9 family hypoxia inducible factor 1 2 2
MIRT547521 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT548546 DR1 down-regulator of transcription 1 2 2
MIRT554545 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 2
MIRT558545 CSNK1A1 casein kinase 1 alpha 1 2 2
MIRT558619 CNOT6L CCR4-NOT transcription complex subunit 6 like 2 4
MIRT563009 U2AF2 U2 small nuclear RNA auxiliary factor 2 2 2
MIRT565148 TUBB2A tubulin beta 2A class IIa 2 2
MIRT567297 HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 2 2
MIRT569071 CADM2 cell adhesion molecule 2 2 2
MIRT570338 VAV3 vav guanine nucleotide exchange factor 3 2 2
MIRT573548 RHOA ras homolog family member A 2 2
MIRT573955 FIGNL1 fidgetin like 1 2 2
MIRT608235 PARP15 poly(ADP-ribose) polymerase family member 15 2 2
MIRT610627 SPTA1 spectrin alpha, erythrocytic 1 2 6
MIRT613784 RPS6 ribosomal protein S6 2 2
MIRT620437 CARNS1 carnosine synthase 1 2 2
MIRT629393 CLEC17A C-type lectin domain containing 17A 2 2
MIRT637409 NKX2-3 NK2 homeobox 3 2 2
MIRT659086 DENR density regulated re-initiation and release factor 2 2
MIRT687349 NUP98 nucleoporin 98 2 2
MIRT688532 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT701007 PCSK6 proprotein convertase subtilisin/kexin type 6 2 2
MIRT715878 ACIN1 apoptotic chromatin condensation inducer 1 2 2
MIRT723149 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4529 Tripterygium wilfordii Hook F resistant tissue
hsa-miR-4529-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

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