miRTarBase - #MIRT523602


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pre-miRNA Information
pre-miRNA hsa-mir-216b   
Genomic Coordinates chr2: 56000714 - 56000795
Description Homo sapiens miR-216b stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-216b-5p
Sequence 11| AAAUCUCUGCAGGCAAAUGUGA |32
Evidence Experimental
Experiments Cloned
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs746268253 9 dbSNP
rs777165632 10 dbSNP
rs528642031 11 dbSNP
rs1168114631 14 dbSNP
rs559876972 16 dbSNP
rs1415888803 17 dbSNP
rs756876970 18 dbSNP
rs930279879 18 dbSNP
rs777776673 19 dbSNP
rs1182789155 21 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B5PHM2 miR-216b Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma MiRNA qPCR analyses
Gene Information
Gene Symbol FZD5   
Synonyms C2orf31, HFZ5
Description frizzled class receptor 5
Transcript NM_003468   
Expression
Putative miRNA Targets on FZD5
3'UTR of FZD5
(miRNA target sites are highlighted)		 
>FZD5|NM_003468|3'UTR
   1 GAGGCTGCCGCCGAGGGACTCGGCCGGAGAGCTGAGGGGAGGGGGGCGTTTTGTTTGGTAGTTTTGCCAAGGTCACTTCC
  81 GTTTACCTTCATGGTGCTGTTGCCCCCTCCCGCGGCGACTTGGAGAGAGGGAAGAGGGGCGTTTTCGAGGAAGAACCTGT
 161 CCCAGGTCTTCTCCAAGGGGCCCAGCTCACGTGTATTCTATTTTGCGTTTCTTACTGCCTTCTTTATGGGAACCCTCTTT
 241 TTAATTTATATGTATTTTTCTTAATTTGTAACTTTGTTGCATTTTGGCAACAATTTACCTTTGCTTTGGGGGCTTTACAA
 321 TCCTAAGGTTGGCGTTGTAATGAAGTTCCACTTGGTTCAGGTTTCTTTGAACTGTGTGGTCTCAATTGGGAAAATATATT
 401 TCCTATACGTGTGTCTTTAAAAAAAAATGTGAACAGTGAACGTTTCGGTTGCTGTGACTGGGAAGTTGTTGGGTGTGCTT
 481 TTTCAGCCAGCTTCTCCTTCCACTGCTTAAAGTGTCCATGATTCTTTAAGGTGAGCTGCAGTTTATAGCCCCAGGTCATA
 561 CCTAGGAGGGGAGCATAATGAGCTCAGGGCCTCCCCAAAGTGACAAGGTTAGGGAGTGCTTAGCGGTTTTGTGTTCAGCC
 641 TTAGCTTTGTTTATAGAGGGAGGTTCAGTTTCTTTTCTGTAGTGCTTGTAATAATTCTCACTCCTAACAGCACCATCGTT
 721 GTGTCTTGAATAAGTTAGAGGTAGCATTATAGAGGATCTGGCATAAATATTTGCAGTAGTGAGAGCCTAAGCGATGGTGA
 801 TTGGTGGAGCTTGAATTTTAGGCTGGTGAGATGGCAGCTTTGTGCCTGAGAGGTAGTGGGTGGTTCTTAAGCTTCAGTGA
 881 TCCCCTTTTTTTTTTTTTTTTTTTTTTTTTAAGGAACTTGTGTTATAATTTTGGTAAAAGTATAAACCCACTCCCTCTGG
 961 ACAATACTTAGCGACAGTTGCTAAAGGGGGCTCCTTTTTAAATGTAAGGACTGAAATGGATATACTTCTAATAAGTAAAT
1041 TTCCAACACTTATTTGCTCCACCCCCTCCCCCCTCCCCCCTCCCCCTTTATCATGTTAAACAGCCTTTTTGCTTTTCTTA
1121 TTCCTCCTCTCCTGGAGAGCTGTGATTAGAAACCACACCCACCCTTGAATGAAGTGCTTGAACTGGGGGAGGGAGGCTGG
1201 CTACCTGTGAACAAACATTGGCCCAAATAAGGGAAAATAAGTGTTCCTGGACTTTGGACTAGTTTATAGCCAGATATTCC
1281 AAGAGCAGCAAGACGTTGCTCTCTGCCGTCTCTGAAAACAAAAGAGATGCATAACATGCTTGCACAACCTTTTAAAATAT
1361 AGATCAGTATAGTGCTACCTCTATAGTTTTCTTCCTCTTCTGAGAAAGCCTGTATATTGATGATCACACACACACACACT
1441 TTGCAATTAGAGAATTTGGTTTGCTTTACTAATCTGTTTAACTATTCCTTCATTCATTATGAACGCTTATATTGATGAAC
1521 ATACACACAGAGGTTTCTTTGCTATTAGAAAATTCTGTTTGCTTTCCTAATCTGTTTAAGCATTCATTCATGAAGAGTGT
1601 GGGGCCATTACTGGGGAAGGGGGGTGACAGTGCCTCAGCCAGCAAAATACCAATGACCAGGATTGGGGACTAAATTTAGG
1681 AAGCTAAAATGGCCAGAGCAATTAACATTTGAGAAAATCCTGTCTAGGAAAACAACTTGAGTGTAGGCATTTGTAATTCA
1761 CTTATACCAAAGTTGGAAAAGTAAAATTTAAGCCTAGGACAATTTTTACTTCATGGATGTTAAATAGACAAATGCATAGT
1841 TCCCAGGGGGAATTTAAACACTTTACTGGTGGGAAGAAACCTAGTATTAAAGTTGTAAGGACTCTCAAAAACTTCACATT
1921 TATTAAAATGCACTGCTCTTACCCAATTTATCCTCTGAATTAAAATTTCAGTGGATTCTACAAAACCTCGTACAAATAGC
2001 TACAGAACTTTGTGCCTATTTTATTCCTCTATTTATTCTTCTAGGAAGAAGCCTCTTCCTAGAATCTTGAAATAGATCCC
2081 TTGACTGAATGCCAATTCCTCTCCTGTTTTTCAAATGAGAGAACCTTTTCTGATCACCTTGACCTTTTCCCTCATTTCAT
2161 ATGTCTTCCCAGAAAGTAGACAGACTGCTCTGCTGCCTTCAGTCATTGTGCCTCATTTGGGTTGTCCCTCCTTCTTTGTG
2241 GAGAAATCTGGAAATGATGCACAGTGTATCCAAAAGTTGTGGGATGAAGTGGATGAAAGTGATTTAATTCATTTTTAGAA
2321 TTTTTTTTTGTTTTGTTTTAGCAACATGCTGAACAACTAATTTACTTTAAAAATAAGCCAGTTAAAACAAAGGACGCTAA
2401 GCCCAAGTGGGGGGCAATATTAGTCAGGATCTTTGGGGTCTAATTCCAGACCAACTTTCAGAAGCACTTCTTTGTCTCTG
2481 TTCTCACCTCTGCTGTCCCTCTCTTCCCTCATCCCCTAAGAGAGACAAAGATAAAAGCCCACCTGCATCCCTAAGTCTTA
2561 CTGAGATCAGCCACCCCAGGGGAGAGAAACTGGATCTACTTACAGCCACCCCCTGTTTCCATCCATATACTTACTTCCCC
2641 CAATTTGCATGTGATTATGGAAACAAGTCATGCTCATGAAAGCAACTGTAAAATAAAAGGTTATGGAGTAGTTCAGCAAC
2721 TTCTTCACAGCCAGCTTTGTGGAGCTGGGGAGGACTTAGGGCCCATTGGAGTCTCTTATGTGTACAGCTTCAGGGCTGTC
2801 CCTTTCAGTTTGATTTTAAGCAATGCCTCACTTCATAGCTTAGGGGGTAAGGATTCCATTCAGGTAGGTTGTCTAAAGGA
2881 ACTAATGGGACCTCTCAGTGAATTAGCTGACCAGATTTTAGGAAATCTTTTTAATTTCTATGATTTTCCTTCTCACATTT
2961 TGAAATGGTAAAATTGACTGGAAATAATTTTTCTTGGTGCCTTATTGGTTTTCCTTGCAAACCTTTCTCATATTTTCTCA
3041 TGACCATTGCCAGTGACCAAGGCCCATGTGTGTGTTGTGTGTAATTGTGGGCATGTACAAGCTTAAATAACGTGCCGACA
3121 GCACTGTTTCAAAGTTGGTATTCATTAGGCTGTTGCCTCCTGGGCTGGAGCTGCGCTAATCCTGACACCGGCTGCCAGGA
3201 GAAAACCTCATGGATCACACACCAAACCTTAATAACAGCATCCGTGACCTGCACTCTCCAGTACAGAATGGGAACCCCAG
3281 AGCTAGGAAATGTAGTTGTATATTTTAATGAACTGCTACCCCAGCCAAAGAAGCTTCTTTCACTTTTGTGCTCTACAGAA
3361 AGCCCAAGGGGGGTAGGAGGGACAGAGCTTTGAATAACTGCTTTCTAACACTAAATGTGGCCAACAGGACAGAGCACATC
3441 ACACGTATAGGCAGGTGTGAGGGACAGTGGCTAAGAATTGCCTGCTCCCTCTGCATGCTCTTTCTTGTTTCCAAAGTCCA
3521 ATCAAGTGATCCTGGGAAACAAATCTGTCTGGATTGCGGAGGGTGGTTCTGAAAGAACTGCCAAGACGTTAAAGAAGGGT
3601 GAAGAGTAGGCAGAATATAAGTAGCTAACCTGAGTCAAGACTCTCAAAAGCTAGCAGCCTGATGACAATAGGATTTATTT
3681 CAGCCAGGATAGTGTCTGTCTGTGAGTGCATCATTTTAAGACAGTATGACTTCATGTTGTTACAAACTATGTATAGTATG
3761 TATGTTTTGTGGGTTGTATATATACATAATATATATTATATATATATATGAGAGATTTGGTGACTTTTGATACGGGTTTG
3841 GTGCAGGTGAATTTATTACTGAGCCAAATGAGGCACATACCGAGTCAGTAGTTGAAGTCCAGGGCATTCGATACTGTTTA
3921 TGATTTCCATATATGTATAGTGCCTATCCCATGCTGTAGTCACTGTTATGTTAAATCCAGAAGTTACACTAGAGCCAGCG
4001 ATACTTTATTTGTAGACAATCAATTTGAATCCATATGTTATTACTGGCAGATGATACATGATTACAGTTCTGAATCTGTA
4081 ACACTTACAAAAGGAAACCCAGAGCAGCTTGATGAGTTTTTGTTTCTGCTTCGTTCCTGGGAGTCAGTAGAAACAGCAGT
4161 TGTATGTGGTTATGTTAGTCTCAAGATACTTAATTTGTTGACCTTACTTCAGAAAAATTTTGTATGTATTATATTTGTGG
4241 GAAGGTAAAATAATCATTTGAGATTTTTATCAAATATGAAGATTAGTTATTTATGAAAAACAAAGAAATGTCTATTTTTC
4321 TTTGTTCCCAATTAATGTAGATAAATTTTAAAATGCATTAAAGTAATGGTAAAGACAATAAAAAGATGCTGTAGAAAAAA
4401 AAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agUGUAAACGGACGUCUCUAAa 5'
            |:|| | : || ||||||| 
Target 5' atATATATATATG-AGAGATTt 3'
 3798 - 3818 155.00 -9.70
2 
miRNA  3' agUGU-AAACGGACGUCUCUAAa 5'
            ||| |||||   :||||| | 
Target 5' acACACTTTGCAATTAGAGAATt 3'
 1434 - 1456 132.00 -14.82
3 
miRNA  3' agUGUAAACGGACGUCUCUAAa 5'
            |||  | |   |||||:|| 
Target 5' gaACA--TACACACAGAGGTTt 3'
 1517 - 1536 132.00 -11.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31490668 17 COSMIC
COSN30521291 25 COSMIC
COSN26976931 26 COSMIC
COSN30153224 27 COSMIC
COSN30153209 28 COSMIC
COSN30106079 40 COSMIC
COSN31507286 53 COSMIC
COSN30466644 105 COSMIC
COSN30447211 106 COSMIC
COSN6165867 229 COSMIC
COSN19662560 296 COSMIC
COSN30174503 418 COSMIC
COSN23632809 427 COSMIC
COSN31490639 520 COSMIC
COSN31961781 677 COSMIC
COSN28729280 709 COSMIC
COSN26458083 770 COSMIC
COSN18778603 885 COSMIC
COSN25086329 1157 COSMIC
COSN31595705 1247 COSMIC
COSN20097767 1424 COSMIC
COSN9306130 1433 COSMIC
COSN31517836 1452 COSMIC
COSN29286092 1481 COSMIC
COSN9306129 1504 COSMIC
COSN29451471 1512 COSMIC
COSN22353925 1569 COSMIC
COSN9306128 2000 COSMIC
COSN2482963 2207 COSMIC
COSN29511505 2214 COSMIC
COSN26691210 2396 COSMIC
COSN20097766 2613 COSMIC
COSN6165866 2656 COSMIC
COSN31521170 2787 COSMIC
COSN1820777 2984 COSMIC
COSN31583926 3049 COSMIC
COSN31513860 3117 COSMIC
COSN24299544 3238 COSMIC
COSN30174014 3392 COSMIC
COSN24976071 3504 COSMIC
COSN31553474 3557 COSMIC
COSN5495428 3574 COSMIC
COSN31567822 3575 COSMIC
COSN9306127 3671 COSMIC
COSN31532094 3796 COSMIC
COSN31544621 3834 COSMIC
COSN26573149 3900 COSMIC
COSN31530680 3904 COSMIC
COSN31582473 3910 COSMIC
COSN31485504 4055 COSMIC
COSN31606995 4320 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs13429572 2 dbSNP
rs1252746547 8 dbSNP
rs1472390827 9 dbSNP
rs770081021 11 dbSNP
rs776168873 12 dbSNP
rs770398696 15 dbSNP
rs773125033 16 dbSNP
rs1387826090 18 dbSNP
rs989209733 21 dbSNP
rs1163951279 22 dbSNP
rs748002513 22 dbSNP
rs778520376 26 dbSNP
rs746031009 28 dbSNP
rs920567138 29 dbSNP
rs973411336 30 dbSNP
rs770101168 31 dbSNP
rs1286132245 35 dbSNP
rs535280944 37 dbSNP
rs781487290 39 dbSNP
rs757398217 40 dbSNP
rs751631220 45 dbSNP
rs1262093112 46 dbSNP
rs1380072898 47 dbSNP
rs1285650732 70 dbSNP
rs1307154829 76 dbSNP
rs1379230718 80 dbSNP
rs1270570773 81 dbSNP
rs1216111540 90 dbSNP
rs1312583109 91 dbSNP
rs1357952062 93 dbSNP
rs1000660229 104 dbSNP
rs766882565 105 dbSNP
rs1482967646 110 dbSNP
rs541760352 111 dbSNP
rs1239471973 115 dbSNP
rs953186356 117 dbSNP
rs1402519820 129 dbSNP
rs1312777985 139 dbSNP
rs572731070 140 dbSNP
rs1004234744 141 dbSNP
rs555759953 151 dbSNP
rs542453735 162 dbSNP
rs779488180 168 dbSNP
rs901743327 171 dbSNP
rs1036064740 175 dbSNP
rs576549360 175 dbSNP
rs970905061 179 dbSNP
rs1335741291 190 dbSNP
rs1359412470 191 dbSNP
rs1446586127 192 dbSNP
rs1467569929 198 dbSNP
rs1021564569 200 dbSNP
rs555846140 204 dbSNP
rs1231242416 207 dbSNP
rs1299058906 210 dbSNP
rs1339105645 217 dbSNP
rs1213215149 222 dbSNP
rs1481703060 230 dbSNP
rs539119927 232 dbSNP
rs1479482479 233 dbSNP
rs1009247882 234 dbSNP
rs1209429328 235 dbSNP
rs1233834626 240 dbSNP
rs1191875115 241 dbSNP
rs887538135 243 dbSNP
rs893570016 245 dbSNP
rs761373854 249 dbSNP
rs996467441 254 dbSNP
rs1466353951 256 dbSNP
rs1189107347 262 dbSNP
rs1209842273 279 dbSNP
rs1389519889 294 dbSNP
rs1474281122 296 dbSNP
rs576449228 304 dbSNP
rs553386789 310 dbSNP
rs937508891 312 dbSNP
rs927423698 320 dbSNP
rs1231408525 323 dbSNP
rs1040955274 328 dbSNP
rs1390177313 331 dbSNP
rs1321763564 334 dbSNP
rs943977568 340 dbSNP
rs908349969 342 dbSNP
rs192374431 344 dbSNP
rs1346237653 350 dbSNP
rs913470198 352 dbSNP
rs3739161 354 dbSNP
rs1221561086 359 dbSNP
rs1331283838 361 dbSNP
rs1209470730 373 dbSNP
rs988829734 376 dbSNP
rs369132422 379 dbSNP
rs577960889 380 dbSNP
rs186942485 385 dbSNP
rs538052975 386 dbSNP
rs534056763 394 dbSNP
rs959351499 397 dbSNP
rs1173775223 405 dbSNP
rs569024676 407 dbSNP
rs550319912 408 dbSNP
rs982365927 410 dbSNP
rs971405630 417 dbSNP
rs1021092856 419 dbSNP
rs954109220 425 dbSNP
rs1299599354 426 dbSNP
rs1326177657 428 dbSNP
rs1332015114 428 dbSNP
rs1404761780 428 dbSNP
rs553699213 435 dbSNP
rs533429949 441 dbSNP
rs1028810891 442 dbSNP
rs1352587874 447 dbSNP
rs975882026 456 dbSNP
rs1449418419 463 dbSNP
rs1260222857 469 dbSNP
rs988275975 473 dbSNP
rs1211545251 478 dbSNP
rs1401540494 480 dbSNP
rs1336507328 484 dbSNP
rs957744949 487 dbSNP
rs1468660428 488 dbSNP
rs966028833 490 dbSNP
rs768323790 492 dbSNP
rs74471859 495 dbSNP
rs1361549798 499 dbSNP
rs1473520396 502 dbSNP
rs887413663 513 dbSNP
rs1165473405 517 dbSNP
rs1392116875 520 dbSNP
rs371014693 533 dbSNP
rs1406056656 538 dbSNP
rs1001310225 539 dbSNP
rs1410659423 548 dbSNP
rs905599795 549 dbSNP
rs1334025918 550 dbSNP
rs547795523 564 dbSNP
rs1247124679 566 dbSNP
rs756738872 573 dbSNP
rs1458402385 576 dbSNP
rs1008119360 582 dbSNP
rs1219899749 583 dbSNP
rs1276510001 588 dbSNP
rs78533900 608 dbSNP
rs1046893500 624 dbSNP
rs747455586 625 dbSNP
rs564150204 626 dbSNP
rs1462554493 628 dbSNP
rs867136037 633 dbSNP
rs183765443 639 dbSNP
rs1187661581 648 dbSNP
rs1386340349 653 dbSNP
rs778237571 654 dbSNP
rs772517803 667 dbSNP
rs1308660185 668 dbSNP
rs985412740 690 dbSNP
rs562711207 694 dbSNP
rs1297784682 699 dbSNP
rs1381620410 702 dbSNP
rs1397801129 704 dbSNP
rs6724297 709 dbSNP
rs926620377 710 dbSNP
rs1243668039 712 dbSNP
rs1299801541 717 dbSNP
rs1404965406 718 dbSNP
rs1226459256 728 dbSNP
rs192758843 730 dbSNP
rs1484035192 736 dbSNP
rs1200461424 741 dbSNP
rs1241983844 749 dbSNP
rs1459633658 754 dbSNP
rs1182253717 757 dbSNP
rs1453106695 763 dbSNP
rs1343460003 770 dbSNP
rs949627503 776 dbSNP
rs1160566827 777 dbSNP
rs914142266 779 dbSNP
rs1371487658 783 dbSNP
rs1467774769 785 dbSNP
rs1177498699 789 dbSNP
rs553448130 793 dbSNP
rs988388084 801 dbSNP
rs1384863793 802 dbSNP
rs867857844 812 dbSNP
rs1425410945 821 dbSNP
rs1322412381 822 dbSNP
rs1365863642 823 dbSNP
rs1014856039 824 dbSNP
rs1032496478 831 dbSNP
rs975108922 834 dbSNP
rs964150327 836 dbSNP
rs533825962 838 dbSNP
rs116740700 840 dbSNP
rs1233502435 849 dbSNP
rs1262171620 855 dbSNP
rs886818910 862 dbSNP
rs1287486906 867 dbSNP
rs1210079960 868 dbSNP
rs1270515142 875 dbSNP
rs201741699 882 dbSNP
rs1216708076 884 dbSNP
rs10932208 885 dbSNP
rs1025557987 886 dbSNP
rs1435332401 886 dbSNP
rs1491499169 886 dbSNP
rs398091022 886 dbSNP
rs66864429 886 dbSNP
rs1161474496 887 dbSNP
rs201847302 887 dbSNP
rs766932608 887 dbSNP
rs750698934 888 dbSNP
rs878954863 889 dbSNP
rs1313911752 890 dbSNP
rs1387176355 890 dbSNP
rs1027353359 891 dbSNP
rs1382118382 891 dbSNP
rs1001195482 892 dbSNP
rs1300055412 893 dbSNP
rs1420450141 895 dbSNP
rs1215680032 896 dbSNP
rs1365187693 896 dbSNP
rs1259529211 898 dbSNP
rs1161950818 899 dbSNP
rs1223713976 901 dbSNP
rs1268371651 907 dbSNP
rs995450797 910 dbSNP
rs1156799536 911 dbSNP
rs1184693544 911 dbSNP
rs1221611986 911 dbSNP
rs1351569977 911 dbSNP
rs1408790542 911 dbSNP
rs1418625890 911 dbSNP
rs1425000300 911 dbSNP
rs1491516621 911 dbSNP
rs1491308700 912 dbSNP
rs1324040057 913 dbSNP
rs1247083964 916 dbSNP
rs1291494555 918 dbSNP
rs1368775595 920 dbSNP
rs1192240812 923 dbSNP
rs1489978463 925 dbSNP
rs1207535416 933 dbSNP
rs1233704413 935 dbSNP
rs905611299 936 dbSNP
rs1024026292 937 dbSNP
rs554850837 938 dbSNP
rs898311562 939 dbSNP
rs1415794182 947 dbSNP
rs1055652791 954 dbSNP
rs1162919813 955 dbSNP
rs1490062401 964 dbSNP
rs1289098945 965 dbSNP
rs938080345 967 dbSNP
rs1329075253 968 dbSNP
rs1211318028 972 dbSNP
rs868278059 973 dbSNP
rs1382966480 976 dbSNP
rs537720529 978 dbSNP
rs1227171860 986 dbSNP
rs1339073651 987 dbSNP
rs1231112799 988 dbSNP
rs1273907068 990 dbSNP
rs867874860 993 dbSNP
rs1053271960 1004 dbSNP
rs1400661673 1008 dbSNP
rs1202777698 1009 dbSNP
rs140782053 1016 dbSNP
rs1301393231 1017 dbSNP
rs1052619703 1018 dbSNP
rs1391726151 1020 dbSNP
rs1241236965 1028 dbSNP
rs1167044719 1031 dbSNP
rs1460324488 1032 dbSNP
rs762054531 1033 dbSNP
rs1171346031 1045 dbSNP
rs1418260223 1053 dbSNP
rs1407851136 1056 dbSNP
rs932615862 1060 dbSNP
rs1479811322 1062 dbSNP
rs552434641 1066 dbSNP
rs1266102134 1067 dbSNP
rs1381253273 1067 dbSNP
rs698910 1069 dbSNP
rs1451763487 1071 dbSNP
rs975562886 1072 dbSNP
rs1361771894 1074 dbSNP
rs1213006901 1075 dbSNP
rs963792479 1076 dbSNP
rs944576532 1078 dbSNP
rs74496675 1080 dbSNP
rs1261110473 1081 dbSNP
rs1466200302 1081 dbSNP
rs983292937 1084 dbSNP
rs952091573 1086 dbSNP
rs1192536741 1087 dbSNP
rs1429594644 1087 dbSNP
rs1474331643 1087 dbSNP
rs920469378 1089 dbSNP
rs1260531315 1090 dbSNP
rs1173641861 1092 dbSNP
rs979771362 1095 dbSNP
rs571001987 1104 dbSNP
rs1319613707 1110 dbSNP
rs1326183997 1112 dbSNP
rs1219737909 1113 dbSNP
rs912299821 1116 dbSNP
rs1346404699 1121 dbSNP
rs1273081033 1127 dbSNP
rs1281446308 1130 dbSNP
rs188198620 1132 dbSNP
rs13403275 1133 dbSNP
rs1283523332 1134 dbSNP
rs1025335382 1140 dbSNP
rs1445025839 1142 dbSNP
rs1269081434 1145 dbSNP
rs1014444614 1149 dbSNP
rs995397036 1156 dbSNP
rs1389429046 1158 dbSNP
rs755989566 1164 dbSNP
rs955802864 1166 dbSNP
rs1159614452 1170 dbSNP
rs1384905379 1197 dbSNP
rs1399265508 1200 dbSNP
rs1032289780 1213 dbSNP
rs1366649127 1222 dbSNP
rs137896933 1229 dbSNP
rs1301574215 1239 dbSNP
rs1331817030 1256 dbSNP
rs1239896244 1257 dbSNP
rs548881262 1259 dbSNP
rs1348470825 1260 dbSNP
rs182855924 1263 dbSNP
rs1173810495 1265 dbSNP
rs996815767 1269 dbSNP
rs1478106676 1270 dbSNP
rs1362826244 1271 dbSNP
rs1252273034 1272 dbSNP
rs1179276675 1273 dbSNP
rs1458828134 1280 dbSNP
rs1240375594 1282 dbSNP
rs1180491675 1285 dbSNP
rs1363664498 1286 dbSNP
rs761697207 1287 dbSNP
rs1199673171 1293 dbSNP
rs555793104 1294 dbSNP
rs1386225834 1295 dbSNP
rs1277194884 1296 dbSNP
rs940131948 1298 dbSNP
rs1046905593 1301 dbSNP
rs1048063607 1304 dbSNP
rs1013696626 1307 dbSNP
rs892443116 1308 dbSNP
rs546035109 1314 dbSNP
rs920523200 1324 dbSNP
rs375174240 1325 dbSNP
rs1315695467 1329 dbSNP
rs936893370 1331 dbSNP
rs1309640393 1332 dbSNP
rs979990193 1333 dbSNP
rs537571869 1344 dbSNP
rs577014972 1345 dbSNP
rs62189218 1349 dbSNP
rs1194935568 1363 dbSNP
rs942856689 1365 dbSNP
rs1247784123 1367 dbSNP
rs1357353857 1369 dbSNP
rs1462303797 1380 dbSNP
rs912757279 1383 dbSNP
rs1244327009 1384 dbSNP
rs1444338529 1385 dbSNP
rs1163137016 1388 dbSNP
rs1336133300 1395 dbSNP
rs1414517889 1402 dbSNP
rs986936143 1403 dbSNP
rs539900967 1430 dbSNP
rs916929484 1433 dbSNP
rs1394386018 1440 dbSNP
rs143129767 1440 dbSNP
rs559781962 1440 dbSNP
rs763971401 1440 dbSNP
rs534070908 1442 dbSNP
rs1297458770 1450 dbSNP
rs1326861832 1452 dbSNP
rs1031380416 1455 dbSNP
rs1441091564 1463 dbSNP
rs775616573 1466 dbSNP
rs1325017497 1469 dbSNP
rs1380545998 1473 dbSNP
rs1203777171 1485 dbSNP
rs968829134 1486 dbSNP
rs1028550890 1496 dbSNP
rs1179642441 1499 dbSNP
rs191887654 1504 dbSNP
rs1429524347 1515 dbSNP
rs973741562 1517 dbSNP
rs763543903 1519 dbSNP
rs962580814 1527 dbSNP
rs1004216414 1530 dbSNP
rs1177257218 1537 dbSNP
rs887196465 1541 dbSNP
rs762524700 1542 dbSNP
rs1468151463 1556 dbSNP
rs566698110 1557 dbSNP
rs1385358738 1561 dbSNP
rs150302476 1568 dbSNP
rs1283601617 1572 dbSNP
rs1024162105 1574 dbSNP
rs899019394 1580 dbSNP
rs1014059038 1591 dbSNP
rs1223522110 1605 dbSNP
rs1282085264 1605 dbSNP
rs770842078 1607 dbSNP
rs1214560276 1611 dbSNP
rs892559031 1620 dbSNP
rs1052348659 1622 dbSNP
rs1263049972 1624 dbSNP
rs1287093720 1625 dbSNP
rs1000820641 1650 dbSNP
rs1261221947 1663 dbSNP
rs1376762352 1669 dbSNP
rs760655728 1673 dbSNP
rs761021486 1690 dbSNP
rs942988316 1697 dbSNP
rs891263228 1708 dbSNP
rs934311735 1709 dbSNP
rs1051283653 1721 dbSNP
rs1295753147 1729 dbSNP
rs1421055042 1731 dbSNP
rs1360764295 1741 dbSNP
rs924370209 1745 dbSNP
rs929677378 1763 dbSNP
rs918342722 1768 dbSNP
rs1412012760 1772 dbSNP
rs528269308 1773 dbSNP
rs575634986 1791 dbSNP
rs1309717042 1792 dbSNP
rs773486517 1794 dbSNP
rs1318056611 1800 dbSNP
rs1239048433 1806 dbSNP
rs1284312438 1809 dbSNP
rs968421890 1810 dbSNP
rs772604626 1818 dbSNP
rs1223459065 1829 dbSNP
rs1268480692 1832 dbSNP
rs748620879 1834 dbSNP
rs1179039230 1842 dbSNP
rs1251068623 1848 dbSNP
rs1418426599 1857 dbSNP
rs1156839892 1858 dbSNP
rs927002712 1859 dbSNP
rs975547888 1865 dbSNP
rs1425102235 1872 dbSNP
rs774454195 1873 dbSNP
rs1347773083 1884 dbSNP
rs1443661935 1886 dbSNP
rs1298250454 1892 dbSNP
rs768625017 1899 dbSNP
rs548475332 1900 dbSNP
rs887090411 1908 dbSNP
rs1286980477 1909 dbSNP
rs1361983648 1917 dbSNP
rs529871453 1918 dbSNP
rs866148054 1919 dbSNP
rs988609423 1920 dbSNP
rs1291670064 1930 dbSNP
rs955915214 1931 dbSNP
rs1233510995 1932 dbSNP
rs905270683 1938 dbSNP
rs1244916319 1942 dbSNP
rs1031038449 1946 dbSNP
rs1000934893 1950 dbSNP
rs903843509 1953 dbSNP
rs948495185 1954 dbSNP
rs375614281 1962 dbSNP
rs1353387017 1969 dbSNP
rs1340652389 1973 dbSNP
rs1329850903 1978 dbSNP
rs544359512 1989 dbSNP
rs1453752949 1990 dbSNP
rs895730520 1990 dbSNP
rs1377512019 1995 dbSNP
rs566627038 2002 dbSNP
rs1274014591 2007 dbSNP
rs1351261889 2008 dbSNP
rs891383571 2012 dbSNP
rs1196844650 2016 dbSNP
rs1051661561 2021 dbSNP
rs1167330643 2027 dbSNP
rs1461707364 2029 dbSNP
rs1203019530 2038 dbSNP
rs1235496927 2039 dbSNP
rs1476291384 2042 dbSNP
rs1186709712 2043 dbSNP
rs1418382748 2044 dbSNP
rs1476523256 2047 dbSNP
rs1177977762 2053 dbSNP
rs559128127 2064 dbSNP
rs1470582384 2065 dbSNP
rs1334142023 2077 dbSNP
rs924325538 2079 dbSNP
rs1433352780 2084 dbSNP
rs897360542 2095 dbSNP
rs757596966 2096 dbSNP
rs1340124490 2099 dbSNP
rs947174082 2124 dbSNP
rs188216788 2129 dbSNP
rs1324422297 2143 dbSNP
rs921013074 2145 dbSNP
rs975557808 2147 dbSNP
rs1448471035 2151 dbSNP
rs756473292 2159 dbSNP
rs1216256792 2163 dbSNP
rs76167276 2165 dbSNP
rs1479100309 2169 dbSNP
rs575261060 2171 dbSNP
rs1487103049 2181 dbSNP
rs1198790256 2195 dbSNP
rs1020302101 2202 dbSNP
rs1479847268 2204 dbSNP
rs926924830 2207 dbSNP
rs1248736604 2209 dbSNP
rs951703168 2212 dbSNP
rs1319383515 2219 dbSNP
rs1222028218 2226 dbSNP
rs552008973 2229 dbSNP
rs979801308 2230 dbSNP
rs1437060477 2237 dbSNP
rs1305226755 2240 dbSNP
rs949968852 2248 dbSNP
rs1346182001 2254 dbSNP
rs1232659950 2256 dbSNP
rs1272946733 2263 dbSNP
rs1352760660 2264 dbSNP
rs1224339289 2265 dbSNP
rs917172769 2270 dbSNP
rs1351299379 2291 dbSNP
rs140587248 2292 dbSNP
rs1269192898 2301 dbSNP
rs1450480089 2303 dbSNP
rs1196137487 2310 dbSNP
rs1234179056 2321 dbSNP
rs3731568 2325 dbSNP
rs1220338519 2326 dbSNP
rs1032829153 2329 dbSNP
rs1023691048 2330 dbSNP
rs1159700892 2330 dbSNP
rs905280684 2330 dbSNP
rs1318558099 2335 dbSNP
rs1366448645 2340 dbSNP
rs780899146 2347 dbSNP
rs1321667827 2350 dbSNP
rs183430531 2351 dbSNP
rs1337673323 2359 dbSNP
rs1282016254 2364 dbSNP
rs968172054 2367 dbSNP
rs1018656312 2369 dbSNP
rs1369280628 2378 dbSNP
rs1247916249 2392 dbSNP
rs1293791336 2392 dbSNP
rs1437601274 2395 dbSNP
rs1006894559 2406 dbSNP
rs1179764930 2409 dbSNP
rs1437943892 2409 dbSNP
rs1238121951 2414 dbSNP
rs895625980 2419 dbSNP
rs1185818561 2425 dbSNP
rs891159753 2435 dbSNP
rs1057350850 2447 dbSNP
rs1329763933 2449 dbSNP
rs1398690675 2450 dbSNP
rs1410635434 2451 dbSNP
rs555315894 2453 dbSNP
rs1330536238 2458 dbSNP
rs1467578938 2459 dbSNP
rs1374576094 2465 dbSNP
rs1454577435 2468 dbSNP
rs1315452523 2474 dbSNP
rs1339705599 2474 dbSNP
rs1242119711 2475 dbSNP
rs1271597410 2476 dbSNP
rs1339412478 2478 dbSNP
rs1424981938 2488 dbSNP
rs1175439408 2489 dbSNP
rs1431582985 2492 dbSNP
rs1427495214 2493 dbSNP
rs1257276913 2508 dbSNP
rs151328748 2513 dbSNP
rs1439344085 2521 dbSNP
rs1185641458 2525 dbSNP
rs1375026632 2527 dbSNP
rs1236094526 2530 dbSNP
rs1170054631 2536 dbSNP
rs1398274608 2540 dbSNP
rs994449641 2542 dbSNP
rs551062600 2550 dbSNP
rs560452345 2551 dbSNP
rs947017068 2552 dbSNP
rs1394089229 2563 dbSNP
rs540336669 2565 dbSNP
rs1297200857 2585 dbSNP
rs771798968 2591 dbSNP
rs1038561841 2595 dbSNP
rs1005272679 2600 dbSNP
rs1275746600 2603 dbSNP
rs138673417 2615 dbSNP
rs1039403083 2619 dbSNP
rs368696482 2625 dbSNP
rs6435388 2630 dbSNP
rs1264379276 2631 dbSNP
rs544269964 2643 dbSNP
rs1193274633 2649 dbSNP
rs916932638 2654 dbSNP
rs951699812 2669 dbSNP
rs1481475886 2671 dbSNP
rs1176637676 2672 dbSNP
rs1377008315 2675 dbSNP
rs1464295410 2676 dbSNP
rs1374201131 2677 dbSNP
rs1385480859 2689 dbSNP
rs1307451706 2699 dbSNP
rs1052950410 2700 dbSNP
rs1401663344 2715 dbSNP
rs934595546 2716 dbSNP
rs925757376 2731 dbSNP
rs115875814 2734 dbSNP
rs968496831 2738 dbSNP
rs752267796 2745 dbSNP
rs1176925052 2751 dbSNP
rs1439247154 2753 dbSNP
rs558898280 2765 dbSNP
rs545275557 2766 dbSNP
rs764836243 2777 dbSNP
rs57763126 2779 dbSNP
rs1216109222 2782 dbSNP
rs1261327432 2785 dbSNP
rs955388145 2788 dbSNP
rs55805603 2801 dbSNP
rs1266850839 2813 dbSNP
rs1179995692 2823 dbSNP
rs1484211197 2827 dbSNP
rs1161267229 2835 dbSNP
rs768419689 2839 dbSNP
rs994393807 2844 dbSNP
rs961631658 2847 dbSNP
rs1418901605 2857 dbSNP
rs1156408208 2867 dbSNP
rs10203715 2871 dbSNP
rs1436491894 2872 dbSNP
rs774736289 2874 dbSNP
rs1364938780 2878 dbSNP
rs1287803241 2881 dbSNP
rs1242735700 2882 dbSNP
rs769347049 2885 dbSNP
rs1309822607 2892 dbSNP
rs1378180603 2898 dbSNP
rs1378043838 2901 dbSNP
rs1239891522 2913 dbSNP
rs903114063 2914 dbSNP
rs541174050 2916 dbSNP
rs1361851468 2918 dbSNP
rs1042922608 2925 dbSNP
rs1312491560 2926 dbSNP
rs1394761435 2938 dbSNP
rs1178842071 2940 dbSNP
rs1381978417 2948 dbSNP
rs1011212577 2954 dbSNP
rs899529078 2956 dbSNP
rs1303443057 2958 dbSNP
rs1005717462 2966 dbSNP
rs1419239514 2968 dbSNP
rs568510169 2973 dbSNP
rs1163682791 2983 dbSNP
rs1358822682 3005 dbSNP
rs1039329722 3016 dbSNP
rs1401663391 3022 dbSNP
rs943834780 3023 dbSNP
rs749376285 3025 dbSNP
rs1229075868 3034 dbSNP
rs555037512 3039 dbSNP
rs1014446465 3043 dbSNP
rs114366204 3047 dbSNP
rs1162434617 3051 dbSNP
rs1457260452 3055 dbSNP
rs1425424473 3062 dbSNP
rs113794740 3066 dbSNP
rs568866521 3068 dbSNP
rs1473021685 3070 dbSNP
rs1180869970 3080 dbSNP
rs916614353 3086 dbSNP
rs552472638 3094 dbSNP
rs934543420 3098 dbSNP
rs532631514 3100 dbSNP
rs1031466169 3101 dbSNP
rs998709690 3102 dbSNP
rs1329963584 3107 dbSNP
rs190886101 3111 dbSNP
rs1355247955 3112 dbSNP
rs779757357 3113 dbSNP
rs1449249213 3114 dbSNP
rs371930594 3116 dbSNP
rs1377255682 3117 dbSNP
rs1220767455 3121 dbSNP
rs1243088124 3123 dbSNP
rs1317414622 3132 dbSNP
rs530309286 3135 dbSNP
rs943207746 3140 dbSNP
rs910405590 3145 dbSNP
rs1314114029 3146 dbSNP
rs1442725248 3148 dbSNP
rs770118155 3166 dbSNP
rs746100573 3174 dbSNP
rs185192048 3175 dbSNP
rs1338455770 3178 dbSNP
rs544282363 3178 dbSNP
rs530520301 3179 dbSNP
rs564842862 3180 dbSNP
rs1300148000 3181 dbSNP
rs115913290 3189 dbSNP
rs145487396 3190 dbSNP
rs972733551 3209 dbSNP
rs1459306514 3213 dbSNP
rs1368958173 3219 dbSNP
rs1299061721 3230 dbSNP
rs1047222636 3237 dbSNP
rs1398244374 3241 dbSNP
rs559599411 3242 dbSNP
rs535109214 3243 dbSNP
rs1006247915 3244 dbSNP
rs1425104676 3248 dbSNP
rs916833943 3249 dbSNP
rs970235256 3251 dbSNP
rs1023575688 3252 dbSNP
rs1262053895 3254 dbSNP
rs1013973782 3258 dbSNP
rs1486991203 3261 dbSNP
rs746878041 3264 dbSNP
rs1450629324 3276 dbSNP
rs1246851636 3278 dbSNP
rs1264901428 3282 dbSNP
rs1478636483 3283 dbSNP
rs895574798 3289 dbSNP
rs376034169 3290 dbSNP
rs1421927468 3292 dbSNP
rs1159414604 3300 dbSNP
rs2292299 3303 dbSNP
rs998473566 3316 dbSNP
rs1434300003 3317 dbSNP
rs1360132922 3318 dbSNP
rs180790287 3327 dbSNP
rs1274221088 3328 dbSNP
rs190657775 3331 dbSNP
rs1325591737 3337 dbSNP
rs1331799979 3340 dbSNP
rs1435638189 3343 dbSNP
rs1273041717 3348 dbSNP
rs1378780406 3349 dbSNP
rs565261125 3350 dbSNP
rs978603576 3351 dbSNP
rs968089426 3355 dbSNP
rs943304627 3356 dbSNP
rs537921967 3357 dbSNP
rs1021446404 3361 dbSNP
rs1450570049 3364 dbSNP
rs375140775 3369 dbSNP
rs1052042333 3370 dbSNP
rs748671588 3373 dbSNP
rs1007906603 3374 dbSNP
rs370660296 3386 dbSNP
rs1391497218 3389 dbSNP
rs1321448219 3396 dbSNP
rs922680089 3415 dbSNP
rs972847711 3420 dbSNP
rs939991773 3424 dbSNP
rs1388276943 3427 dbSNP
rs1447512981 3429 dbSNP
rs909909212 3430 dbSNP
rs764745622 3435 dbSNP
rs1038588208 3437 dbSNP
rs1284445815 3442 dbSNP
rs970726101 3444 dbSNP
rs948165126 3445 dbSNP
rs1259501822 3446 dbSNP
rs1459469841 3447 dbSNP
rs1199874898 3451 dbSNP
rs1330467894 3453 dbSNP
rs1463939761 3468 dbSNP
rs895409681 3473 dbSNP
rs1189823678 3477 dbSNP
rs1057092750 3480 dbSNP
rs1170759358 3481 dbSNP
rs1472472949 3489 dbSNP
rs1023096850 3493 dbSNP
rs1425946279 3501 dbSNP
rs1466057591 3505 dbSNP
rs1330639828 3511 dbSNP
rs1397784888 3514 dbSNP
rs939388264 3517 dbSNP
rs993405871 3520 dbSNP
rs960235027 3521 dbSNP
rs1242224983 3531 dbSNP
rs1031374188 3542 dbSNP
rs923964519 3543 dbSNP
rs1253948079 3548 dbSNP
rs1318046498 3552 dbSNP
rs1219739369 3557 dbSNP
rs1258006321 3558 dbSNP
rs1479830600 3562 dbSNP
rs1202552701 3563 dbSNP
rs978107613 3587 dbSNP
rs558562599 3588 dbSNP
rs904178116 3597 dbSNP
rs1456812315 3598 dbSNP
rs963817039 3606 dbSNP
rs1196419261 3609 dbSNP
rs186643857 3614 dbSNP
rs1467582251 3617 dbSNP
rs1172929332 3621 dbSNP
rs1401289053 3623 dbSNP
rs1273181817 3625 dbSNP
rs1299686144 3639 dbSNP
rs750997294 3640 dbSNP
rs1018208960 3641 dbSNP
rs377336309 3643 dbSNP
rs181083609 3648 dbSNP
rs955305061 3655 dbSNP
rs754581059 3656 dbSNP
rs547260073 3658 dbSNP
rs1256933528 3661 dbSNP
rs1344802621 3670 dbSNP
rs1025766700 3673 dbSNP
rs1007442798 3688 dbSNP
rs889033971 3691 dbSNP
rs1051725890 3708 dbSNP
rs1193035539 3713 dbSNP
rs1308188663 3729 dbSNP
rs993832541 3736 dbSNP
rs1199537139 3751 dbSNP
rs753440162 3754 dbSNP
rs1376812244 3755 dbSNP
rs1444378509 3755 dbSNP
rs144664229 3769 dbSNP
rs1332006127 3774 dbSNP
rs1418785884 3778 dbSNP
rs762073406 3780 dbSNP
rs1012436563 3782 dbSNP
rs1399381833 3787 dbSNP
rs1389002130 3792 dbSNP
rs895283756 3795 dbSNP
rs1056619617 3796 dbSNP
rs1232557038 3798 dbSNP
rs1288683818 3799 dbSNP
rs567799412 3802 dbSNP
rs1354667902 3804 dbSNP
rs1173824349 3805 dbSNP
rs149773919 3806 dbSNP
rs940107889 3808 dbSNP
rs909857528 3809 dbSNP
rs200317390 3810 dbSNP
rs902761008 3811 dbSNP
rs984534278 3812 dbSNP
rs1180276721 3816 dbSNP
rs373198205 3817 dbSNP
rs1380749555 3824 dbSNP
rs1438670234 3833 dbSNP
rs1042371707 3834 dbSNP
rs1351076667 3836 dbSNP
rs916144270 3845 dbSNP
rs1457991279 3849 dbSNP
rs77911328 3863 dbSNP
rs35564745 3866 dbSNP
rs79438790 3881 dbSNP
rs1039070740 3882 dbSNP
rs1311888262 3883 dbSNP
rs1378157815 3886 dbSNP
rs1239640360 3894 dbSNP
rs1183108279 3910 dbSNP
rs113148336 3920 dbSNP
rs1276514357 3922 dbSNP
rs35796012 3929 dbSNP
rs867942412 3932 dbSNP
rs1265009902 3934 dbSNP
rs1467077684 3936 dbSNP
rs977117056 3939 dbSNP
rs1238529580 3942 dbSNP
rs1457179190 3943 dbSNP
rs911075685 3953 dbSNP
rs968452019 3956 dbSNP
rs1285665218 3959 dbSNP
rs1163443410 3961 dbSNP
rs1415087066 3961 dbSNP
rs1460306058 3964 dbSNP
rs1021251456 3968 dbSNP
rs1401414855 3969 dbSNP
rs1441946682 3972 dbSNP
rs1296601655 3979 dbSNP
rs1381612545 3982 dbSNP
rs775663336 3983 dbSNP
rs918473229 3996 dbSNP
rs1237652764 3998 dbSNP
rs190266570 3999 dbSNP
rs528082428 4000 dbSNP
rs1279954175 4004 dbSNP
rs1442959809 4016 dbSNP
rs1447113062 4019 dbSNP
rs559396905 4033 dbSNP
rs541650083 4037 dbSNP
rs768907615 4040 dbSNP
rs962344687 4055 dbSNP
rs528774837 4057 dbSNP
rs1478529053 4074 dbSNP
rs1012029512 4080 dbSNP
rs959142616 4082 dbSNP
rs1035634006 4086 dbSNP
rs80340611 4088 dbSNP
rs1168761634 4089 dbSNP
rs1361313006 4091 dbSNP
rs1448991456 4102 dbSNP
rs542860993 4107 dbSNP
rs1312535922 4112 dbSNP
rs769998290 4113 dbSNP
rs1401939746 4119 dbSNP
rs1156508134 4122 dbSNP
rs14616 4122 dbSNP
rs879078096 4132 dbSNP
rs186049356 4133 dbSNP
rs1382516798 4134 dbSNP
rs1159518836 4138 dbSNP
rs1472725787 4143 dbSNP
rs1010878903 4146 dbSNP
rs893831867 4147 dbSNP
rs1277763835 4156 dbSNP
rs573777004 4162 dbSNP
rs1189702197 4173 dbSNP
rs1475361749 4174 dbSNP
rs1486063624 4177 dbSNP
rs915942366 4178 dbSNP
rs139174009 4179 dbSNP
rs1262717571 4181 dbSNP
rs1185327819 4194 dbSNP
rs754445676 4207 dbSNP
rs1427655456 4210 dbSNP
rs1415429495 4218 dbSNP
rs1038996837 4232 dbSNP
rs1214675027 4236 dbSNP
rs1057296248 4242 dbSNP
rs1284622731 4254 dbSNP
rs1298858827 4256 dbSNP
rs938955512 4259 dbSNP
rs543197421 4269 dbSNP
rs1354157706 4271 dbSNP
rs924753574 4281 dbSNP
rs1367970341 4283 dbSNP
rs1285920178 4290 dbSNP
rs79983442 4294 dbSNP
rs1339210384 4295 dbSNP
rs1216950050 4296 dbSNP
rs1282905637 4309 dbSNP
rs1444811362 4309 dbSNP
rs968897854 4310 dbSNP
rs933807816 4314 dbSNP
rs1478524488 4315 dbSNP
rs1193400922 4327 dbSNP
rs182076995 4331 dbSNP
rs1441741188 4339 dbSNP
rs914299211 4342 dbSNP
rs1384278544 4350 dbSNP
rs918521779 4355 dbSNP
rs1325367945 4363 dbSNP
rs1350391244 4380 dbSNP
rs1440156321 4383 dbSNP
rs1323619770 4385 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 7855.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000295417.3 | 3UTR | UGUAUAUAUACAUAAUAUAUAUUAUAUAUAUAUAUGAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC 0.295 0.03 0.324 0.02 44 Click to see details
LUSC 0.668 0.07 0.371 0.23 6 Click to see details
KIRC 0.609 0.1 0.543 0.13 6 Click to see details
CHOL -0.471 0.17 -0.657 0.08 6 Click to see details
PRAD -0.29 0.21 -0.042 0.45 10 Click to see details
KIRP -0.41 0.3 -0.200 0.4 4 Click to see details
THCA 0.098 0.35 0.077 0.38 18 Click to see details
LUAD 0.414 0.36 -0.500 0.33 3 Click to see details
STAD 0.174 0.37 -0.086 0.44 6 Click to see details
PAAD 0.176 0.44 0.500 0.33 3 Click to see details
UCEC -0.165 0.45 -0.500 0.33 3 Click to see details
BLCA 0.096 0.45 0.400 0.3 4 Click to see details
HNSC 0.017 0.49 0.071 0.44 7 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
KICH 0.003 0.5 -0.100 0.44 5 Click to see details
129 hsa-miR-216b-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT006144 KRAS KRAS proto-oncogene, GTPase 3 1
MIRT007207 CSNK2A1 casein kinase 2 alpha 1 3 1
MIRT064260 KIAA1804 mitogen-activated protein kinase kinase kinase 21 2 2
MIRT169957 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 6
MIRT362970 CDK6 cyclin dependent kinase 6 2 2
MIRT437983 BECN1 beclin 1 3 2
MIRT443073 ABLIM1 actin binding LIM protein 1 2 2
MIRT443747 ZFAND5 zinc finger AN1-type containing 5 2 6
MIRT445488 KLF12 Kruppel like factor 12 2 2
MIRT447818 ZCCHC11 zinc finger CCHC-type containing 11 2 2
MIRT448753 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT460391 GUF1 GUF1 homolog, GTPase 2 2
MIRT466481 TECPR2 tectonin beta-propeller repeat containing 2 2 7
MIRT472205 NGFRAP1 brain expressed X-linked 3 2 4
MIRT473269 MID1 midline 1 2 2
MIRT489831 P2RY2 purinergic receptor P2Y2 2 2
MIRT497753 OXGR1 oxoglutarate receptor 1 2 2
MIRT502881 CDK4 cyclin dependent kinase 4 2 8
MIRT505904 RIMS3 regulating synaptic membrane exocytosis 3 2 6
MIRT506657 MAPK1 mitogen-activated protein kinase 1 2 4
MIRT510190 MON1B MON1 homolog B, secretory trafficking associated 2 4
MIRT512406 CD84 CD84 molecule 2 2
MIRT520342 UBXN2A UBX domain protein 2A 2 2
MIRT523602 FZD5 frizzled class receptor 5 2 2
MIRT529598 C6orf132 chromosome 6 open reading frame 132 2 2
MIRT534444 SDR16C5 short chain dehydrogenase/reductase family 16C member 5 2 2
MIRT534739 RBM47 RNA binding motif protein 47 2 2
MIRT537285 GABPB1 GA binding protein transcription factor beta subunit 1 2 2
MIRT546979 PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2 2 2
MIRT549862 MCM4 minichromosome maintenance complex component 4 2 2
MIRT552535 ZIC5 Zic family member 5 2 2
MIRT555322 PPP2CB protein phosphatase 2 catalytic subunit beta 2 2
MIRT555661 PGM3 phosphoglucomutase 3 2 2
MIRT559128 C11orf57 chromosome 11 open reading frame 57 2 2
MIRT567802 DEK DEK proto-oncogene 2 2
MIRT567866 DCAF12 DDB1 and CUL4 associated factor 12 2 2
MIRT574661 KLHL15 kelch like family member 15 2 2
MIRT575029 Tecpr2 tectonin beta-propeller repeat containing 2 2 5
MIRT607227 ACSM2A acyl-CoA synthetase medium chain family member 2A 2 4
MIRT609385 FAM216B family with sequence similarity 216 member B 2 4
MIRT612266 PDZD4 PDZ domain containing 4 2 2
MIRT617434 ANP32E acidic nuclear phosphoprotein 32 family member E 2 4
MIRT619453 NUP214 nucleoporin 214 2 2
MIRT620242 CCDC65 coiled-coil domain containing 65 2 2
MIRT620463 CENPN centromere protein N 2 2
MIRT620909 MUT methylmalonyl-CoA mutase 2 2
MIRT621006 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT621568 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT622059 SSBP2 single stranded DNA binding protein 2 2 2
MIRT622132 SP4 Sp4 transcription factor 2 2
MIRT623365 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT624370 CDK12 cyclin dependent kinase 12 2 2
MIRT627944 NNT nicotinamide nucleotide transhydrogenase 2 2
MIRT628228 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT630150 ZDHHC9 zinc finger DHHC-type containing 9 2 2
MIRT630237 SORD sorbitol dehydrogenase 2 2
MIRT631271 CENPM centromere protein M 2 2
MIRT637456 ZNF324B zinc finger protein 324B 2 2
MIRT637899 SLC19A3 solute carrier family 19 member 3 2 2
MIRT641610 CAPN7 calpain 7 2 2
MIRT643088 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT643813 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT643911 TCEB2 elongin B 2 2
MIRT644900 ZBED1 zinc finger BED-type containing 1 2 2
MIRT645012 NGRN neugrin, neurite outgrowth associated 2 2
MIRT645521 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT646032 S100A7A S100 calcium binding protein A7A 2 2
MIRT646626 CENPL centromere protein L 2 2
MIRT646721 RHOG ras homolog family member G 2 2
MIRT647196 ZNF583 zinc finger protein 583 2 2
MIRT648010 ZNF431 zinc finger protein 431 2 2
MIRT648362 AKIP1 A-kinase interacting protein 1 2 2
MIRT648400 WRN Werner syndrome RecQ like helicase 2 2
MIRT648833 C8orf37 chromosome 8 open reading frame 37 2 2
MIRT651870 UNC119B unc-119 lipid binding chaperone B 2 2
MIRT652490 TMEM178B transmembrane protein 178B 2 2
MIRT652529 TM9SF4 transmembrane 9 superfamily member 4 2 2
MIRT652536 TM9SF3 transmembrane 9 superfamily member 3 2 2
MIRT652795 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT653379 SMAD1 SMAD family member 1 2 2
MIRT655568 P2RX7 purinergic receptor P2X 7 2 2
MIRT657235 IER5 immediate early response 5 2 2
MIRT657594 GRIN2A glutamate ionotropic receptor NMDA type subunit 2A 2 2
MIRT658037 FZD9 frizzled class receptor 9 2 2
MIRT658151 FGF10 fibroblast growth factor 10 2 2
MIRT658459 FAM117B family with sequence similarity 117 member B 2 2
MIRT658503 EXOC5 exocyst complex component 5 2 2
MIRT659420 COL4A4 collagen type IV alpha 4 chain 2 2
MIRT660023 C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2 2
MIRT660032 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT661206 MPPE1 metallophosphoesterase 1 2 2
MIRT661639 UGT2B28 UDP glucuronosyltransferase family 2 member B28 2 2
MIRT665303 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT668010 HCFC2 host cell factor C2 2 2
MIRT673436 APAF1 apoptotic peptidase activating factor 1 2 2
MIRT673583 KDELC2 KDEL motif containing 2 2 2
MIRT673717 SLU7 SLU7 homolog, splicing factor 2 2
MIRT674315 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT675811 MED28 mediator complex subunit 28 2 2
MIRT686564 TPM3 tropomyosin 3 2 2
MIRT687134 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT687463 NKD1 naked cuticle homolog 1 2 2
MIRT690226 C5orf45 MRN complex interacting protein 2 2
MIRT690532 ZNF566 zinc finger protein 566 2 2
MIRT693077 AS3MT arsenite methyltransferase 2 2
MIRT694083 RNASEH2B ribonuclease H2 subunit B 2 2
MIRT695388 NSA2 NSA2, ribosome biogenesis homolog 2 2
MIRT695638 SLC26A2 solute carrier family 26 member 2 2 2
MIRT696540 C3 complement C3 2 2
MIRT705522 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 2
MIRT711304 ACOX1 acyl-CoA oxidase 1 2 2
MIRT711513 ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 2 2
MIRT711617 LHX5 LIM homeobox 5 2 2
MIRT711647 LIPG lipase G, endothelial type 2 2
MIRT711771 CCDC59 coiled-coil domain containing 59 2 2
MIRT713207 SOCS6 suppressor of cytokine signaling 6 2 2
MIRT715047 PRPF38A pre-mRNA processing factor 38A 2 2
MIRT715620 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT717677 CDC42BPA CDC42 binding protein kinase alpha 2 2
MIRT718016 METTL15 methyltransferase like 15 2 2
MIRT721251 KIAA0922 transmembrane 131 like 2 2
MIRT721438 ARPC4 actin related protein 2/3 complex subunit 4 2 2
MIRT722193 DNAJC9 DnaJ heat shock protein family (Hsp40) member C9 2 2
MIRT723319 PRKCH protein kinase C eta 2 2
MIRT725299 NLRC5 NLR family CARD domain containing 5 2 2
MIRT731866 HDAC8 histone deacetylase 8 3 1
MIRT731987 PARP1 poly(ADP-ribose) polymerase 1 3 1
MIRT735558 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 3 0
MIRT735826 SMAD3 SMAD family member 3 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-216b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-216b 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) NULL 15625 Microarray embryos 22921993 2012 up-regulated
miR-216b Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Quantitative real-time PCR human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Curcumin NULL 969516 Quantitative real-time PCR Y79 RB cells. 22510010 2012 down-regulated
miR-216b Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-216b Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-216b Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-216b-5p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-216b-5p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive High Ovarian Cancer cell line (SKOV3)
hsa-miR-216b-5p Oxaliplatin 6857599 NSC266046 approved sensitive Low Colorectal Cancer cell line (HT-29, HCT8)
hsa-miR-216b-5p Vemurafenib 42611257 NSC761431 approved sensitive Low Melanoma cell line (A375, G-361)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549, PC-9)
hsa-miR-216b-5p Paclitaxel 36314 NSC125973 approved sensitive Low Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive Low Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-216b-5p Cetuximab + Folfox(Fluorouracil + Leucovorin + Oxaliplatin) resistant High Metastatic Colorectal Cancer tissue
hsa-miR-216b-5p Carboplatin 38904 NSC241240 approved resistant Low Non-Small Cell Lung Cancer cell line (A549, NCI-H460)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved resistant Low Non-Small Cell Lung Cancer cell line (A549, NCI-H460)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive Low Osteosarcoma cell line (MG-63, SaOS-2)
hsa-miR-216b-5p Paclitaxel 36314 NSC125973 approved sensitive Low Ovarian Cancer cell line (A2780)
hsa-miR-216b-5p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-216b-5p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-216b-5p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-216b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM17)
hsa-miR-216b-5p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-216b-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-216b-5p Fluorouracil 3385 NSC19893 approved resistant cell line (KM12C) (72 h)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved resistant cell line (RPMI2650)
hsa-miR-216b-5p Oxaliplatin 6857599 NSC266046 approved resistant cell line (IGROV-1)
hsa-miR-216b-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-216b-5p Cetuximab resistant tissue (colorectal carcinoma)

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