>FHL2|NM_001039492|3'UTR
   1 ATTCAACACAGAGAAGTTGCTGCTTGTGATCTCACACACAGATTTTTATGTTTTCTTTCTCACCCAGGCAATCTTGCCTT
  81 CTGGTTTCTTCCAGCCACATTGAGACTTTCTTCTAGTGCTTTTCAGTGATACTCACGTTTGCTTAAACCCTTTAGTGCTT
 161 TGTGATAGTTCAGTCCCAGGGAAAGAGAAAACTCGCCCTAGGCCCTAGGTGGGAAGATGGTTTGAAATTTTTGTAATCGA
 241 GTAAGGCACACCCAAATGTAAAAATCCTTTTGAATGATGCCTTTATAAATCTTTCTCTCACTGTCTATTTAAGTGCAATT
 321 AACATATGTCACGAACTTGAAAGTTTTCTAAACTCAATAAGGTAATGACCAGTTGTTATTTACAGCTCTGTAACCTCCCG
 401 TTGCGTCAAGTCTAAACCAAGATTATGTGACTTGCAATAAAGTTATTCAGAACAGAAAAAAAAAAAAAAAAAAAAAAAAA
 481 AAAAAAAA

ID	Duplex structure	Position	Score	MFE
1	miRNA 3' cuGAUUC--AAAUGUCAAAGAUCc 5' :|:|| ||| | |||||| Target 5' caTTGAGACTTT-C---TTCTAGt 3'	98 - 117	121.00	-5.80
2	miRNA 3' cugAUUCAA----AUGUCAA-AGAUCc 5' |:| || || |||| |: || Target 5' atgTGACTTGCAATAAAGTTATTCAGa 3'	425 - 451	81.00	-5.30
3	miRNA 3' cugauucaaaugucaaaGAUCc 5' |||| Target 5' gaaagagaaaactcgccCTAGg 3'	181 - 202	80.00	-9.30

Mutant ID	Mutant Position	Mutant Source
COSN30145006	15	COSMIC
COSN4893311	24	COSMIC
COSN31557795	28	COSMIC
COSN8407702	31	COSMIC
COSN30106588	33	COSMIC
COSN31508417	41	COSMIC
COSN31529417	46	COSMIC
COSN24309060	55	COSMIC
COSN30467986	67	COSMIC
COSN30152539	88	COSMIC
COSN30534480	99	COSMIC
COSN6672252	102	COSMIC
COSN30152850	113	COSMIC
COSN31554686	132	COSMIC
COSN31507796	156	COSMIC
COSN31526614	158	COSMIC
COSN30528697	161	COSMIC
COSN5475813	204	COSMIC
COSN31567180	208	COSMIC
COSN31603218	301	COSMIC
COSN8980488	302	COSMIC
COSN31537693	348	COSMIC
COSN31534036	354	COSMIC
COSN7454996	658	COSMIC
COSN8264059	1057	COSMIC
COSN29172841	1103	COSMIC
COSN29176232	1114	COSMIC
COSN7454995	1143	COSMIC
COSN21094280	1495	COSMIC
COSN6150649	1698	COSMIC
COSN1776104	1790	COSMIC
COSN1221025	2099	COSMIC
COSN26494470	2194	COSMIC
COSN7454994	2361	COSMIC
COSN1776103	2464	COSMIC
COSN24780088	2883	COSMIC

Mutant ID	Mutant Position	Mutant Source
rs1257674816	9	dbSNP
rs199691250	13	dbSNP
rs756430758	16	dbSNP
rs368824523	30	dbSNP
rs781750373	31	dbSNP
rs757735612	33	dbSNP
rs752238903	37	dbSNP
rs1463367047	40	dbSNP
rs1290529530	41	dbSNP
rs1000798237	50	dbSNP
rs775963548	50	dbSNP
rs1453217065	63	dbSNP
rs1338143273	83	dbSNP
rs530518744	84	dbSNP
rs1392063589	92	dbSNP
rs1295912741	94	dbSNP
rs1308864748	98	dbSNP
rs903741979	100	dbSNP
rs1398684313	101	dbSNP
rs939760066	101	dbSNP
rs1204821226	104	dbSNP
rs1239304356	107	dbSNP
rs1484960127	109	dbSNP
rs1297009989	110	dbSNP
rs778092790	113	dbSNP
rs879204828	116	dbSNP
rs1478919170	118	dbSNP
rs1174014635	131	dbSNP
rs1428264194	132	dbSNP
rs11537577	134	dbSNP
rs945037275	136	dbSNP
rs890907386	137	dbSNP
rs1167556039	147	dbSNP
rs908299857	148	dbSNP
rs1416748178	149	dbSNP
rs1182034016	155	dbSNP
rs1363652833	165	dbSNP
rs1402641267	166	dbSNP
rs1050850135	168	dbSNP
rs758826156	172	dbSNP
rs1247782423	175	dbSNP
rs932361126	176	dbSNP
rs1224479747	177	dbSNP
rs753215391	180	dbSNP
rs952578481	181	dbSNP
rs926496385	182	dbSNP
rs765710296	184	dbSNP
rs1261329295	185	dbSNP
rs980674894	187	dbSNP
rs2278500	194	dbSNP
rs909455005	195	dbSNP
rs983479116	196	dbSNP
rs1192678906	200	dbSNP
rs757512099	201	dbSNP
rs1405788849	216	dbSNP
rs546996537	227	dbSNP
rs1024955854	233	dbSNP
rs1159200732	237	dbSNP
rs992268924	238	dbSNP
rs956979827	239	dbSNP
rs529805708	245	dbSNP
rs1302196363	251	dbSNP
rs1365774780	253	dbSNP
rs959687850	264	dbSNP
rs1276958386	266	dbSNP
rs1283860422	270	dbSNP
rs1371832019	273	dbSNP
rs1033521747	282	dbSNP
rs1001106034	288	dbSNP
rs1307840926	293	dbSNP
rs1373862633	295	dbSNP
rs1337671446	303	dbSNP
rs1220324042	322	dbSNP
rs542257095	324	dbSNP
rs183756866	332	dbSNP
rs11537579	333	dbSNP
rs1230896745	337	dbSNP
rs1395874415	345	dbSNP
rs1044097	348	dbSNP
rs1177663064	353	dbSNP
rs1009213718	357	dbSNP
rs1162368723	362	dbSNP
rs559524401	366	dbSNP
rs1390428008	370	dbSNP
rs540935979	375	dbSNP
rs577099490	377	dbSNP
rs1325951807	385	dbSNP
rs1158839319	392	dbSNP
rs558160021	397	dbSNP
rs766063018	399	dbSNP
rs1332692675	400	dbSNP
rs1379725875	404	dbSNP
rs777604080	405	dbSNP
rs1314453027	406	dbSNP
rs932428413	421	dbSNP
rs1360441266	431	dbSNP
rs1230197110	432	dbSNP
rs899574331	434	dbSNP
rs546264176	441	dbSNP
rs1180477880	448	dbSNP
rs1204918723	450	dbSNP
rs773058177	459	dbSNP
rs942158903	465	dbSNP
rs909494051	466	dbSNP
rs1254844626	472	dbSNP
rs939720033	485	dbSNP
rs908248135	493	dbSNP
rs1473593337	495	dbSNP
rs771990202	498	dbSNP
rs1165744450	499	dbSNP
rs1048149550	515	dbSNP
rs931087687	518	dbSNP
rs926438832	526	dbSNP
rs980622332	530	dbSNP
rs1284675989	531	dbSNP
rs545800352	532	dbSNP
rs970621766	535	dbSNP
rs1451025552	540	dbSNP
rs1336193964	561	dbSNP
rs917855107	567	dbSNP
rs988118893	573	dbSNP
rs956736287	593	dbSNP
rs1219072428	597	dbSNP
rs1032808289	600	dbSNP
rs1321341048	606	dbSNP
rs929520528	608	dbSNP
rs953627539	613	dbSNP
rs575797400	616	dbSNP
rs557448899	623	dbSNP
rs992533551	627	dbSNP
rs535956014	628	dbSNP
rs1426176757	629	dbSNP
rs568532424	635	dbSNP
rs146492348	637	dbSNP
rs1403490726	638	dbSNP
rs967840371	647	dbSNP
rs1020713417	648	dbSNP
rs1306324246	652	dbSNP
rs1009444449	661	dbSNP
rs1400767939	670	dbSNP
rs1004251282	672	dbSNP
rs534985326	679	dbSNP
rs1222651857	680	dbSNP
rs868738452	681	dbSNP
rs1256558269	683	dbSNP
rs1347035694	684	dbSNP
rs1202916644	685	dbSNP
rs1330947616	691	dbSNP
rs1319388479	694	dbSNP
rs1218276173	703	dbSNP
rs1266294210	705	dbSNP
rs1402740182	706	dbSNP
rs1199142847	713	dbSNP
rs1378775763	714	dbSNP
rs1479256441	718	dbSNP
rs758308832	720	dbSNP
rs886767995	725	dbSNP
rs1048574126	728	dbSNP
rs931057392	733	dbSNP
rs571171036	736	dbSNP
rs551747536	737	dbSNP
rs371436181	741	dbSNP
rs530385928	744	dbSNP
rs569315595	745	dbSNP
rs759638777	751	dbSNP
rs367835825	762	dbSNP
rs899606048	765	dbSNP
rs1241640021	766	dbSNP
rs1242565100	766	dbSNP
rs1038516553	770	dbSNP
rs374388549	774	dbSNP
rs1005277469	776	dbSNP
rs1268410501	777	dbSNP
rs1453865158	778	dbSNP
rs1363707128	779	dbSNP
rs1445020405	780	dbSNP
rs1160528491	781	dbSNP
rs191042649	782	dbSNP
rs1424196664	790	dbSNP
rs1047887054	801	dbSNP
rs1392572500	802	dbSNP
rs752675068	806	dbSNP
rs929551597	826	dbSNP
rs918155133	833	dbSNP
rs1056506675	834	dbSNP
rs1377544457	834	dbSNP
rs1425928207	841	dbSNP
rs1312208010	844	dbSNP
rs1358290010	845	dbSNP
rs370111688	859	dbSNP
rs925305017	866	dbSNP
rs1433361443	873	dbSNP
rs926754489	878	dbSNP
rs1238173757	880	dbSNP
rs1458598773	881	dbSNP
rs1325013210	887	dbSNP
rs1180606447	892	dbSNP
rs1297247425	895	dbSNP
rs979866616	901	dbSNP
rs1423496193	902	dbSNP
rs1165807069	906	dbSNP
rs953450768	908	dbSNP
rs1460331019	914	dbSNP
rs1167089628	916	dbSNP
rs1400957504	917	dbSNP
rs1181628906	918	dbSNP
rs1448815813	918	dbSNP
rs1381338133	932	dbSNP
rs1482110740	937	dbSNP
rs1324316657	942	dbSNP
rs1225771232	945	dbSNP
rs1376816118	958	dbSNP
rs1310543761	960	dbSNP
rs1257763531	962	dbSNP
rs1413349543	962	dbSNP
rs1420166253	963	dbSNP
rs1261368399	964	dbSNP
rs1482988087	964	dbSNP
rs1169537911	965	dbSNP
rs1029051443	967	dbSNP
rs1258596072	974	dbSNP
rs76268450	979	dbSNP
rs1474326980	981	dbSNP
rs1192671827	982	dbSNP
rs1424019379	982	dbSNP
rs1448726225	982	dbSNP
rs878876756	982	dbSNP
rs878888921	982	dbSNP
rs1216765720	983	dbSNP
rs1422630335	984	dbSNP
rs112004931	990	dbSNP
rs1220812038	991	dbSNP
rs1486120765	994	dbSNP
rs1312106939	998	dbSNP
rs1259795424	1002	dbSNP
rs1208132903	1003	dbSNP
rs966189992	1017	dbSNP
rs780500623	1020	dbSNP
rs1274368557	1022	dbSNP
rs1015078104	1027	dbSNP
rs553585021	1028	dbSNP
rs12476475	1029	dbSNP
rs1424446924	1039	dbSNP
rs1277958663	1041	dbSNP
rs1177613701	1042	dbSNP
rs1234211111	1043	dbSNP
rs1026636589	1048	dbSNP
rs1298487772	1049	dbSNP
rs62152060	1050	dbSNP
rs1301612355	1051	dbSNP
rs543748813	1056	dbSNP
rs377647070	1057	dbSNP
rs1303527671	1058	dbSNP
rs542694294	1059	dbSNP
rs1239480007	1064	dbSNP
rs765975092	1066	dbSNP
rs541924182	1069	dbSNP
rs373510238	1073	dbSNP
rs1219993795	1075	dbSNP
rs1044841734	1102	dbSNP
rs987928244	1106	dbSNP
rs955359025	1109	dbSNP
rs1408128576	1113	dbSNP
rs768502400	1115	dbSNP
rs144492081	1120	dbSNP
rs1192803434	1124	dbSNP
rs553289161	1125	dbSNP
rs535263208	1126	dbSNP
rs1420326100	1137	dbSNP
rs878886495	1143	dbSNP
rs1381789869	1147	dbSNP
rs1052738261	1151	dbSNP
rs1180300281	1155	dbSNP
rs1322021343	1158	dbSNP
rs935245691	1170	dbSNP
rs1016576568	1175	dbSNP
rs773494868	1179	dbSNP
rs1005308526	1191	dbSNP
rs772483883	1194	dbSNP
rs536094785	1199	dbSNP
rs979433021	1201	dbSNP
rs886823955	1209	dbSNP
rs1257911590	1210	dbSNP
rs776701416	1212	dbSNP
rs1309999653	1213	dbSNP
rs1047957996	1217	dbSNP
rs1356130477	1227	dbSNP
rs1337356198	1236	dbSNP
rs1288912472	1239	dbSNP
rs1291100125	1246	dbSNP
rs537903316	1250	dbSNP
rs921986549	1251	dbSNP
rs577033997	1257	dbSNP
rs1239423292	1263	dbSNP
rs1442420507	1268	dbSNP
rs1162332124	1273	dbSNP
rs1439316627	1285	dbSNP
rs1406385365	1288	dbSNP
rs187042485	1289	dbSNP
rs1376085607	1310	dbSNP
rs966136837	1318	dbSNP
rs771052592	1329	dbSNP
rs537372626	1331	dbSNP
rs1057104230	1371	dbSNP
rs182050060	1377	dbSNP
rs1379149730	1379	dbSNP
rs1445889324	1387	dbSNP
rs952299676	1389	dbSNP
rs12476328	1396	dbSNP
rs1043676429	1397	dbSNP
rs1391982524	1402	dbSNP
rs1270537994	1412	dbSNP
rs535941854	1414	dbSNP
rs1199139916	1415	dbSNP
rs1259886221	1433	dbSNP
rs1459620803	1438	dbSNP
rs946838688	1451	dbSNP
rs373133825	1469	dbSNP
rs904869656	1470	dbSNP
rs1023342549	1486	dbSNP
rs145841286	1489	dbSNP
rs1465584931	1501	dbSNP
rs189702879	1504	dbSNP
rs896261220	1505	dbSNP
rs532291442	1531	dbSNP
rs1412909365	1532	dbSNP
rs1238133488	1553	dbSNP
rs1333519408	1556	dbSNP
rs1359965228	1558	dbSNP
rs748481682	1561	dbSNP
rs114813575	1564	dbSNP
rs116033554	1566	dbSNP
rs1280091563	1568	dbSNP
rs1342770647	1571	dbSNP
rs1199402484	1579	dbSNP
rs1278634292	1580	dbSNP
rs1443819748	1586	dbSNP
rs975755305	1589	dbSNP
rs779434468	1593	dbSNP
rs1261995948	1594	dbSNP
rs963956422	1607	dbSNP
rs921932557	1608	dbSNP
rs185236251	1612	dbSNP
rs1172095502	1613	dbSNP
rs944778527	1619	dbSNP
rs149854162	1621	dbSNP
rs951149090	1640	dbSNP
rs1025379805	1645	dbSNP
rs1400446202	1647	dbSNP
rs1299748706	1653	dbSNP
rs574828810	1660	dbSNP
rs952317511	1661	dbSNP
rs1274952817	1662	dbSNP
rs920824790	1669	dbSNP
rs1346573418	1670	dbSNP
rs980344407	1685	dbSNP
rs896658116	1692	dbSNP
rs1035168595	1703	dbSNP
rs1442989899	1713	dbSNP
rs1368595775	1727	dbSNP
rs1002869031	1728	dbSNP
rs1198834903	1730	dbSNP
rs970337201	1734	dbSNP
rs1479085272	1739	dbSNP
rs905438295	1743	dbSNP
rs1023288426	1751	dbSNP
rs1379931906	1762	dbSNP
rs1420466399	1766	dbSNP
rs1160271358	1772	dbSNP
rs1013288025	1774	dbSNP
rs1043748800	1782	dbSNP
rs1324174639	1783	dbSNP
rs1031170077	1786	dbSNP
rs1444016903	1801	dbSNP
rs946702889	1805	dbSNP
rs999331125	1810	dbSNP
rs1241803205	1818	dbSNP
rs903676227	1822	dbSNP
rs1292733765	1828	dbSNP
rs1354732921	1829	dbSNP
rs892580518	1833	dbSNP
rs1431119470	1841	dbSNP
rs1268735075	1842	dbSNP
rs1346033348	1855	dbSNP
rs1161503283	1858	dbSNP
rs2460258	1862	dbSNP
rs1379743444	1872	dbSNP
rs1043605274	1875	dbSNP
rs1174882776	1876	dbSNP
rs1052486913	1887	dbSNP
rs934067936	1895	dbSNP
rs1180802068	1903	dbSNP
rs559758980	1905	dbSNP
rs922430859	1908	dbSNP
rs773718617	1911	dbSNP
rs1163613464	1919	dbSNP
rs996028535	1921	dbSNP
rs1463960083	1922	dbSNP
rs1330115433	1924	dbSNP
rs1377055132	1931	dbSNP
rs1448307982	1939	dbSNP
rs765974276	1941	dbSNP
rs1190997602	1948	dbSNP
rs1486371262	1950	dbSNP
rs1287643553	1962	dbSNP
rs1339494179	1964	dbSNP
rs1244532929	1965	dbSNP
rs1266335121	1989	dbSNP
rs1337627411	1990	dbSNP
rs749401706	1992	dbSNP
rs900453003	1994	dbSNP
rs568752387	1997	dbSNP
rs1352410578	2004	dbSNP
rs866668899	2007	dbSNP
rs975239900	2010	dbSNP
rs1254408804	2012	dbSNP
rs942645674	2016	dbSNP
rs909796903	2018	dbSNP
rs1310378433	2021	dbSNP
rs1419692885	2022	dbSNP
rs1476703834	2027	dbSNP
rs944726194	2029	dbSNP
rs1214976013	2032	dbSNP
rs541170957	2039	dbSNP
rs35606673	2084	dbSNP
rs780996033	2084	dbSNP
rs1300337130	2091	dbSNP
rs1401060285	2094	dbSNP
rs1398370228	2099	dbSNP
rs1396212408	2100	dbSNP
rs1360054077	2106	dbSNP
rs1313913434	2112	dbSNP
rs1357813710	2113	dbSNP
rs983810333	2115	dbSNP
rs951012985	2116	dbSNP
rs1350972778	2117	dbSNP
rs1313566461	2119	dbSNP
rs960202615	2121	dbSNP
rs1025284009	2129	dbSNP
rs1376458715	2134	dbSNP
rs576996787	2137	dbSNP
rs1483058177	2142	dbSNP
rs755752311	2143	dbSNP
rs959775805	2144	dbSNP
rs183806971	2147	dbSNP
rs1002375325	2149	dbSNP
rs970284770	2154	dbSNP
rs866431172	2158	dbSNP
rs991801283	2169	dbSNP
rs558744175	2180	dbSNP
rs960659391	2182	dbSNP
rs571146288	2184	dbSNP
rs1466086701	2186	dbSNP
rs1022492152	2188	dbSNP
rs72823875	2190	dbSNP
rs150672820	2191	dbSNP
rs1212427280	2195	dbSNP
rs1481965624	2204	dbSNP
rs1052407857	2206	dbSNP
rs536283550	2211	dbSNP
rs192416609	2215	dbSNP
rs995977589	2216	dbSNP
rs1311715387	2217	dbSNP
rs900402194	2221	dbSNP
rs1205108580	2227	dbSNP
rs1282805333	2228	dbSNP
rs1040272038	2230	dbSNP
rs1309099681	2233	dbSNP
rs1039982702	2242	dbSNP
rs76884682	2243	dbSNP
rs74959968	2244	dbSNP
rs74445785	2245	dbSNP
rs942530530	2247	dbSNP
rs1217719456	2250	dbSNP
rs909828104	2251	dbSNP
rs1340140352	2261	dbSNP
rs547420597	2266	dbSNP
rs929852718	2267	dbSNP
rs538376182	2269	dbSNP
rs1418649781	2270	dbSNP
rs36099361	2277	dbSNP
rs960100999	2278	dbSNP
rs1302828868	2279	dbSNP
rs1034087236	2280	dbSNP
rs79154358	2281	dbSNP
rs2576777	2284	dbSNP
rs567607877	2289	dbSNP
rs549017002	2290	dbSNP
rs775469385	2292	dbSNP
rs1318545604	2293	dbSNP
rs530058633	2293	dbSNP
rs1219106222	2294	dbSNP
rs570672840	2299	dbSNP
rs948884727	2299	dbSNP
rs1031453192	2301	dbSNP
rs1194965107	2306	dbSNP
rs1235789039	2312	dbSNP
rs186645533	2325	dbSNP
rs1189585780	2346	dbSNP
rs770962812	2347	dbSNP
rs1402863811	2354	dbSNP
rs1163048667	2358	dbSNP
rs541482731	2361	dbSNP
rs901275471	2363	dbSNP
rs532506034	2366	dbSNP
rs1254853369	2371	dbSNP
rs1022068285	2387	dbSNP
rs1039777303	2396	dbSNP
rs1196379952	2397	dbSNP
rs1006949496	2399	dbSNP
rs10209781	2414	dbSNP
rs1197805495	2420	dbSNP
rs543652423	2421	dbSNP
rs1311668068	2423	dbSNP
rs1048216255	2424	dbSNP
rs1456980643	2428	dbSNP
rs968171652	2429	dbSNP
rs1022018084	2435	dbSNP
rs974507501	2442	dbSNP
rs964524275	2454	dbSNP
rs929883734	2460	dbSNP
rs1475722036	2463	dbSNP
rs576316893	2465	dbSNP
rs1009229324	2481	dbSNP
rs1465227144	2483	dbSNP
rs918506901	2485	dbSNP
rs1356503184	2506	dbSNP
rs1446024634	2515	dbSNP
rs1283409696	2520	dbSNP
rs1355909956	2521	dbSNP
rs1234895232	2529	dbSNP
rs1057227393	2530	dbSNP
rs938349150	2535	dbSNP
rs1218724727	2542	dbSNP
rs886383779	2544	dbSNP
rs1274441332	2555	dbSNP
rs555201511	2556	dbSNP
rs1209036487	2566	dbSNP
rs1237672491	2569	dbSNP
rs979895067	2574	dbSNP
rs1190505856	2575	dbSNP
rs1379789880	2585	dbSNP
rs1477745913	2597	dbSNP
rs1329855601	2601	dbSNP
rs1421686304	2610	dbSNP
rs1412798380	2616	dbSNP
rs878944667	2617	dbSNP
rs1465468485	2626	dbSNP
rs1333830954	2630	dbSNP
rs1376290966	2631	dbSNP
rs968400840	2633	dbSNP
rs915418524	2634	dbSNP
rs989600718	2642	dbSNP
rs1296055994	2646	dbSNP
rs764192918	2646	dbSNP
rs1431339099	2651	dbSNP
rs542953267	2662	dbSNP
rs2679884	2679	dbSNP
rs1271825870	2683	dbSNP
rs1342323769	2684	dbSNP
rs1218115937	2686	dbSNP
rs773372804	2689	dbSNP
rs371893069	2698	dbSNP
rs1349513761	2704	dbSNP
rs1031234947	2708	dbSNP
rs772213941	2717	dbSNP
rs965418926	2725	dbSNP
rs899225133	2734	dbSNP
rs1367463495	2735	dbSNP
rs571978419	2748	dbSNP
rs1018666220	2756	dbSNP
rs1181923568	2761	dbSNP
rs2576776	2762	dbSNP
rs888496772	2766	dbSNP
rs948816058	2771	dbSNP
rs1236320807	2774	dbSNP
rs538721598	2775	dbSNP
rs895983328	2780	dbSNP
rs1258991727	2791	dbSNP
rs1395938771	2799	dbSNP
rs1436768627	2810	dbSNP
rs1057343850	2821	dbSNP
rs934895314	2824	dbSNP
rs1382551299	2827	dbSNP
rs1320274823	2833	dbSNP
rs1048290206	2836	dbSNP
rs747893227	2837	dbSNP
rs75668800	2839	dbSNP
rs897095300	2843	dbSNP
rs946405093	2844	dbSNP
rs778997742	2848	dbSNP
rs914960330	2851	dbSNP
rs1057063644	2852	dbSNP
rs1207773026	2864	dbSNP
rs974458511	2867	dbSNP
rs964472061	2869	dbSNP
rs1265030821	2873	dbSNP
rs1239896156	2874	dbSNP
rs568870680	2877	dbSNP
rs36122701	2879	dbSNP
rs987351671	2884	dbSNP
rs779158603	2886	dbSNP
rs537998314	2890	dbSNP
rs374424405	2891	dbSNP
rs1044006089	2897	dbSNP
rs531798618	2899	dbSNP
rs1379906132	2902	dbSNP
rs914319683	2909	dbSNP
rs1325949918	2912	dbSNP
rs1160017081	2914	dbSNP
rs989630503	2922	dbSNP
rs755429531	2924	dbSNP
rs924075734	2930	dbSNP
rs977048901	2931	dbSNP
rs965973003	2935	dbSNP
rs1396078151	2937	dbSNP
rs1443904347	2938	dbSNP
rs1308167913	2940	dbSNP
rs1018281460	2946	dbSNP
rs1240227904	2966	dbSNP
rs1281589109	2972	dbSNP
rs1354903362	2978	dbSNP
rs1158969630	2980	dbSNP
rs985448984	2988	dbSNP
rs899155244	2995	dbSNP
rs1378427858	2996	dbSNP
rs749808925	2998	dbSNP
rs1469925065	3004	dbSNP
rs1196825008	3006	dbSNP
rs1250085924	3009	dbSNP
rs1419833020	3029	dbSNP
rs562769767	3031	dbSNP
rs1012987446	3051	dbSNP
rs1472323399	3054	dbSNP
rs1027061466	3061	dbSNP
rs999049857	3062	dbSNP
rs1396798519	3064	dbSNP
rs1392735109	3067	dbSNP
rs994226520	3068	dbSNP
rs1043320699	3069	dbSNP
rs903392072	3069	dbSNP
rs1294511741	3086	dbSNP
rs754922461	3089	dbSNP
rs1206116249	3090	dbSNP
rs1337499315	3090	dbSNP
rs947676291	3091	dbSNP
rs12474144	3094	dbSNP
rs914908124	3102	dbSNP
rs1038701374	3103	dbSNP
rs1284511225	3109	dbSNP
rs943112221	3113	dbSNP
rs897006624	3116	dbSNP
rs987686983	3119	dbSNP
rs1348668165	3125	dbSNP
rs1419960553	3136	dbSNP
rs1476773642	3139	dbSNP
rs567353883	3147	dbSNP
rs755666124	3150	dbSNP
rs1169177424	3151	dbSNP
rs759633306	3158	dbSNP
rs1276736137	3160	dbSNP
rs950583523	3164	dbSNP
rs1035893454	3169	dbSNP
rs1463052773	3178	dbSNP
rs1231293619	3180	dbSNP
rs1002801049	3186	dbSNP
rs1313807013	3188	dbSNP
rs72945003	3189	dbSNP
rs1318664622	3193	dbSNP
rs1295452888	3199	dbSNP
rs1044081231	3202	dbSNP
rs1229681036	3206	dbSNP
rs1254551062	3210	dbSNP
rs142435725	3219	dbSNP
rs1297496586	3227	dbSNP
rs1259309143	3231	dbSNP
rs779974109	3232	dbSNP
rs1185911269	3248	dbSNP
rs1262331035	3252	dbSNP
rs1429847584	3254	dbSNP
rs1196050060	3261	dbSNP
rs749978395	3265	dbSNP
rs1170332672	3273	dbSNP
rs1434898705	3277	dbSNP
rs1174691947	3284	dbSNP
rs1477464419	3286	dbSNP
rs1052814741	3292	dbSNP
rs1418226089	3302	dbSNP
rs566052040	3309	dbSNP
rs934381163	3314	dbSNP
rs1012935144	3318	dbSNP
rs1479004700	3332	dbSNP
rs1384013187	3337	dbSNP
rs1261553309	3341	dbSNP
rs924134240	3347	dbSNP
rs960085402	3357	dbSNP
rs977289294	3364	dbSNP
rs944335873	3367	dbSNP
rs139237155	3371	dbSNP
rs1280774911	3378	dbSNP
rs1214799479	3385	dbSNP
rs999394268	3386	dbSNP
rs1198819100	3388	dbSNP
rs985490001	3396	dbSNP
rs1251788172	3407	dbSNP
rs1454308052	3415	dbSNP
rs1195161156	3416	dbSNP
rs1378081761	3418	dbSNP
rs182053140	3420	dbSNP
rs1158745850	3430	dbSNP
rs1346332657	3432	dbSNP
rs1026965124	3444	dbSNP
rs972817186	3451	dbSNP
rs565075625	3458	dbSNP
rs1455773569	3466	dbSNP
rs543517376	3468	dbSNP
rs189415933	3484	dbSNP
rs1035563672	3488	dbSNP
rs1305988370	3494	dbSNP
rs1374865068	3495	dbSNP
rs1223014453	3498	dbSNP
rs73945097	3503	dbSNP
rs905803134	3507	dbSNP
rs1219330474	3510	dbSNP
rs1272448690	3514	dbSNP
rs1038646520	3541	dbSNP
rs943058168	3544	dbSNP
rs1277376746	3555	dbSNP
rs1415284107	3560	dbSNP
rs62155875	3562	dbSNP
rs1331561096	3563	dbSNP
rs63302162	3564	dbSNP
rs561343624	3566	dbSNP

- Nature methods, 2011

Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.

- Nature, 2013

Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.