miRTarBase - #MIRT523969


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pre-miRNA Information
pre-miRNA hsa-mir-4316   
Genomic Coordinates chr17: 77396984 - 77397054
Description Homo sapiens miR-4316 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4316
Sequence 11| GGUGAGGCUAGCUGGUG |27
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs989002279 5 dbSNP
rs957742923 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol DVL3   
Synonyms DRS3
Description dishevelled segment polarity protein 3
Transcript NM_004423   
Expression
Putative miRNA Targets on DVL3
3'UTR of DVL3
(miRNA target sites are highlighted)		 
>DVL3|NM_004423|3'UTR
   1 GCAGGGCCCCTCCCCCAGCTCCATTCCGCTCCCACCCCAGCCGGCTGCGTTCCTCTCTCCATCCGTCCGTCTTTTTTACT
  81 TTGTCTGGTACCTGAAAGGGAAATAAAAGGAACTAAATCCAGGTGCGCTAACTGCTCGCAGGGTGCTGCGAGGGTGGGGT
 161 GCACCTACCGATTGGCTCTGCAGCCCCCTAACCTGCCTCTGGCCCCAGTTCGTTTCCTCTGCCCACTAATCCCTGCGCAG
 241 GACTTCCCAGGACCCCTTTTGTCTCTGGGACCAGACTTGTTGGTGCTACCCCTTACTCCCCTCTGCAACCCCCATTTTGG
 321 GAGTTGACCCCAGCAATGACCTTGGTGGCACGCTCACTCCCTCATTCTCTCGTTTCCCCTTTAGCTCCCTTTCACCATTT
 401 ATTCAGCTACATCATCCCTCTATTAACCCCACCCCATCAGGCACGTGTGCAAACCTCTTGACTTTACCCCACATTACTGA
 481 AACCAAAATATATTTGCTTCATCTGCCCCTACTAACCATCCCCCTGCCTGCTGCCTCAGTCCTGCAACCTAAAGCTGTAG
 561 TCGCCTCCAATAGCCATCCATGCCATCCCTGCCTGTGCCTAGATCAGAGGCCCAGAGGGCCCCCTCAGTTGCCTGAGCAG
 641 CTGGTGGCTTCCAGGGAGCATCTCTGCTCTACCCCTGCCCCATGCCTGCCCTGCGTGCTGGTTCCTTCAGACCCCTAACC
 721 CTACTAACCAGCAGGCTCATCTCACCTCCAGGCCTGAAACATTTCTTTTCTTTCTTTTTTCCTCCCCCAATTTACCCTGG
 801 GCCTGGAGCAGCCAAGAATTTCGGGCTGTTTGACTTTCTGTGAGCCCCCAGCGAGGGGAGGCCCAGCCTCCGAGGAGACC
 881 AGGAACCCTGCTTCAGCAGCCCCTCAGGGCTTCCCAAGGATGTCCAGCCCCCACACCCACACGTTAACATAATGAGTCAC
 961 TAGGCTTCTGGGGAGGGCCCAACTTCACCCATGCATGAGAGACTCTCCTCCTTTCCAGAGAGAATCGGATCGCACCACGT
1041 GTGGCAGCCTGCGGCGGGGGGAGGGGGGCCTCTTTAGCTCTCTTTATCTTTCTCTCTCACTCATGTATGCATACATGCAC
1121 AGAGATGCATACACAGGTGCCTATGCAAGTTCATTTAAGCCTCAGGGCTGGTCCCTGCCCAAAGGGCTGGACCCTCCTAA
1201 TCCTCTCCTAGGTTGTGGGGCTGGTCCCCTGACACCCTTCTCCCCTTCCTGGTAGACCTTAAACCTCGCACACATGTCCC
1281 CAGCATTTTCTCACCTGGATAAAGCCCATAAGCTGGGTCTCAGGCTGGGCTCAGCAAAGGACTCGCCTTGCAACCGACAG
1361 GCCATTCCCACCCCCACACACAACCTCCCCTGTTTTCACATTCACCATGGCATCCCAGAGCAAGGACACAGGAGCCCACA
1441 GGCCAGTTGAGGTTGGGCAAGGAGACTTCCAGGACTTCCAGACAGAGTACCAGGTTTTATTTTTCACCTTATTCTCTACT
1521 TTAAACAAATCATAACTTTCTCTTTAAGCCTCTGCTATAAATTCTCCTGGCTCTCCTGGGCTTCCATATTTTGGGGGCTG
1601 GGGTGTCAAAAGTGAGATGAAGTTCTTAGCTCCAGGTTTTGGGGTAAACCAAGGTAGGAACATTTTGGCATTTATTTCAA
1681 TTAACAATACTTCCTTGGACGGGTGCGGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCTGAGACAGGTGGATCAC
1761 TTGAGGTCGGGAGTTCGAGACCAGCCTGGCCAACATAGCAAAACCCTGTCTCTACTAAAAATACAAAAATTAGATGGGTG
1841 TTTTGGCACCTGCCTGTAATCTCAGCTACTCAGGAGGCTGAGGCACAAGAATCGCTTGAATCCAGGAAGCAAGCGGAGGT
1921 TGCAGTGAGTTGAGATCGCACTCCAGCCTGGGTGACAGAGTGAGATTCTGTCTCAAAAGCAAACTAACAAAGAAAAACAA
2001 TACTTCCTGGGGTTTTGGTGTGCAGAGGGCTTTGTTGGAAGTGTGACTCAATCTTGCCTGCCTTCTGGGAGCTCTAGAAT
2081 TGTTCCCAACCCAGTCCATGGCTTCTAGCCACCACTACAGGGCTGTTTCATGTACTTCTCTCTCTGACTCTGTCTTGTCC
2161 GACTCTCTTGAGAATTTCTCAACGATTGCTCATGCCTGTCAGTATCAGTGCTTCCATCGTTCCATCTTTGATTCACTTCT
2241 CTTTCCTTTCTATTTACTCCCAAAATGGAGTCATTCATCCTGATGTCCTCAATTGCTGCTGATATGCTGGTGATTCCCAA
2321 ATACATAGCTCCAACCCCCAACTTCCCCCAGACTTTAGATCTGTATTGGTATTACCTACTGGACATCTCTATGGACAGTT
2401 CCGTATAGACTCAACTCATCTGCCCAACCAAGTATGTTCCTCCTGAATTCCTCTCCTGGTTACTTCATCACAATCTACAT
2481 AGGCTCACCAGCTAGAAACATTTATGAGCTTACATTCCTTCTTCCCATATCTTATCAGCATATCATATCCATTTCACTCC
2561 AACACTCTGTCTTGAATTTGGCCCTCCCTCTCCCCTCTCTACTTTAATTCATTGGAGCATGGGATTTGGAGTTAGGTGGT
2641 TTTGGGTTTGAATTCCAGCTCTACTATTTTTGGTTGTGTGATAGAGTTATTTAACCTCTCTGAGCCTCAGTTCCCTCGTA
2721 TGTAAAATGATGATAATAATACCTACCTCACAGGGTTGTTGTGAGGATTTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' guGGUCGAUCGGAGUgg 5'
            || ||| ||||||  
Target 5' tgCCTGCT-GCCTCAgt 3'
 525 - 540 134.00 -16.10
2 
miRNA  3' guGGUCGA-UCGGAGUgg 5'
            :|| :| |||||||  
Target 5' gtTCATTTAAGCCTCAgg 3'
 1149 - 1166 131.00 -10.10
3 
miRNA  3' guggucGA-UCGGAGUgg 5'
                || |||||||  
Target 5' acctctCTGAGCCTCAgt 3'
 2694 - 2711 127.00 -12.80
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30474160 15 COSMIC
COSN30163854 32 COSMIC
COSN30102065 45 COSMIC
COSN30516729 49 COSMIC
COSN30499594 61 COSMIC
COSN27183393 86 COSMIC
COSN31590822 123 COSMIC
COSN30110812 127 COSMIC
COSN19728344 182 COSMIC
COSN30120770 212 COSMIC
COSN9765867 322 COSMIC
COSN1273119 501 COSMIC
COSN32179443 665 COSMIC
COSN29793440 994 COSMIC
COSN24330817 1070 COSMIC
COSN29183589 1147 COSMIC
COSN30109709 1250 COSMIC
COSN31533782 1275 COSMIC
COSN32179444 1515 COSMIC
COSN32179445 1543 COSMIC
COSN9538958 1718 COSMIC
COSN19316979 1792 COSMIC
COSN15036758 1861 COSMIC
COSN1935928 2305 COSMIC
COSN6757488 2324 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs763811429 2 dbSNP
rs1486547672 4 dbSNP
rs753597614 5 dbSNP
rs1215435693 7 dbSNP
rs1235009620 11 dbSNP
rs757125018 15 dbSNP
rs1431545231 16 dbSNP
rs375446517 17 dbSNP
rs1374784484 27 dbSNP
rs1466044209 28 dbSNP
rs941679203 30 dbSNP
rs201130951 32 dbSNP
rs750440761 36 dbSNP
rs1382258102 41 dbSNP
rs1381346832 43 dbSNP
rs1298752700 44 dbSNP
rs1320915922 46 dbSNP
rs1367882840 49 dbSNP
rs1232729000 50 dbSNP
rs201563126 51 dbSNP
rs768739805 53 dbSNP
rs1383896759 55 dbSNP
rs898067068 56 dbSNP
rs1191535693 58 dbSNP
rs776756739 61 dbSNP
rs1033731220 66 dbSNP
rs778731787 69 dbSNP
rs959644482 69 dbSNP
rs1424365894 73 dbSNP
rs1374040495 79 dbSNP
rs867337253 80 dbSNP
rs1003574429 81 dbSNP
rs984057860 82 dbSNP
rs1017160965 88 dbSNP
rs748310453 94 dbSNP
rs961591042 99 dbSNP
rs1485653225 100 dbSNP
rs1192229942 105 dbSNP
rs756440326 114 dbSNP
rs1248394676 115 dbSNP
rs1490379588 119 dbSNP
rs778154891 122 dbSNP
rs1191519452 129 dbSNP
rs1270533561 129 dbSNP
rs1225611063 136 dbSNP
rs894650038 138 dbSNP
rs749596621 139 dbSNP
rs1177572269 140 dbSNP
rs922754920 142 dbSNP
rs1021670091 143 dbSNP
rs955188201 149 dbSNP
rs1320884143 154 dbSNP
rs771370377 155 dbSNP
rs1439082953 156 dbSNP
rs779285214 162 dbSNP
rs1397653180 163 dbSNP
rs113162122 165 dbSNP
rs968658898 168 dbSNP
rs1221482879 170 dbSNP
rs746446875 171 dbSNP
rs771512631 172 dbSNP
rs1229097993 173 dbSNP
rs977385389 174 dbSNP
rs985615330 176 dbSNP
rs1430841224 180 dbSNP
rs910937478 191 dbSNP
rs774986675 192 dbSNP
rs1432293613 193 dbSNP
rs1250810127 195 dbSNP
rs1193625780 196 dbSNP
rs1467334080 197 dbSNP
rs1479556471 198 dbSNP
rs1032129800 200 dbSNP
rs1211534365 203 dbSNP
rs935664654 212 dbSNP
rs1252193372 213 dbSNP
rs956632180 216 dbSNP
rs1232793280 227 dbSNP
rs567955860 237 dbSNP
rs78433447 238 dbSNP
rs868676302 239 dbSNP
rs36096459 242 dbSNP
rs1227215338 246 dbSNP
rs1389980427 251 dbSNP
rs1376691669 255 dbSNP
rs1337928239 256 dbSNP
rs1471280257 257 dbSNP
rs1029733775 258 dbSNP
rs923099293 263 dbSNP
rs1465108529 274 dbSNP
rs1045626015 276 dbSNP
rs1183570915 277 dbSNP
rs907033342 277 dbSNP
rs1001342675 278 dbSNP
rs1268149542 290 dbSNP
rs1237388514 291 dbSNP
rs1184128717 294 dbSNP
rs1462644332 295 dbSNP
rs1261193211 300 dbSNP
rs1199876636 306 dbSNP
rs1351533856 311 dbSNP
rs931820575 322 dbSNP
rs985838334 328 dbSNP
rs1055631607 329 dbSNP
rs1353430678 332 dbSNP
rs908967762 337 dbSNP
rs941791271 339 dbSNP
rs1036025941 341 dbSNP
rs765907677 341 dbSNP
rs1211359185 346 dbSNP
rs1316239612 348 dbSNP
rs895210557 349 dbSNP
rs1381135712 353 dbSNP
rs185266182 357 dbSNP
rs575260877 358 dbSNP
rs1385115524 364 dbSNP
rs1057509635 368 dbSNP
rs765686256 369 dbSNP
rs1361960660 373 dbSNP
rs771720662 378 dbSNP
rs1469528751 380 dbSNP
rs1021782660 385 dbSNP
rs545500057 387 dbSNP
rs369734425 394 dbSNP
rs998920301 400 dbSNP
rs557709493 405 dbSNP
rs572856410 415 dbSNP
rs1203600530 421 dbSNP
rs1031660002 423 dbSNP
rs955733857 434 dbSNP
rs35493813 444 dbSNP
rs1248566483 453 dbSNP
rs1412727255 470 dbSNP
rs965771358 471 dbSNP
rs976001228 473 dbSNP
rs1030665361 474 dbSNP
rs953157088 478 dbSNP
rs1319788825 485 dbSNP
rs759205735 485 dbSNP
rs1359428590 487 dbSNP
rs548026042 491 dbSNP
rs375851251 493 dbSNP
rs1326162637 498 dbSNP
rs775125122 500 dbSNP
rs1334546323 508 dbSNP
rs909082432 510 dbSNP
rs1191510954 514 dbSNP
rs941741202 521 dbSNP
rs1488020447 525 dbSNP
rs752429670 531 dbSNP
rs972251505 531 dbSNP
rs748669501 532 dbSNP
rs189737364 536 dbSNP
rs561721989 546 dbSNP
rs1196875913 549 dbSNP
rs1330592326 550 dbSNP
rs149535046 556 dbSNP
rs1216208328 561 dbSNP
rs989841566 564 dbSNP
rs773496460 566 dbSNP
rs1283490839 568 dbSNP
rs576440883 570 dbSNP
rs1211446876 590 dbSNP
rs1043188835 600 dbSNP
rs1322578003 604 dbSNP
rs904730061 622 dbSNP
rs1248091653 623 dbSNP
rs1398491209 630 dbSNP
rs1168470151 636 dbSNP
rs945656591 647 dbSNP
rs1430125675 653 dbSNP
rs998868123 656 dbSNP
rs1477197553 663 dbSNP
rs113306532 665 dbSNP
rs901134057 667 dbSNP
rs1182899210 668 dbSNP
rs928541263 669 dbSNP
rs998601030 672 dbSNP
rs1028356506 673 dbSNP
rs1263284496 675 dbSNP
rs1224832476 676 dbSNP
rs533437340 679 dbSNP
rs1055616043 681 dbSNP
rs1442599730 682 dbSNP
rs895252713 683 dbSNP
rs1329180103 685 dbSNP
rs953271289 687 dbSNP
rs1005585958 690 dbSNP
rs1406908441 691 dbSNP
rs1178609374 695 dbSNP
rs1368087703 696 dbSNP
rs1424680152 699 dbSNP
rs1178020113 702 dbSNP
rs551561130 711 dbSNP
rs1471349604 714 dbSNP
rs1236803947 722 dbSNP
rs1178555032 726 dbSNP
rs1007503987 733 dbSNP
rs1245515132 735 dbSNP
rs1211563948 736 dbSNP
rs1038375670 737 dbSNP
rs1016090258 739 dbSNP
rs963227355 744 dbSNP
rs34611231 748 dbSNP
rs1352572319 750 dbSNP
rs1306885824 756 dbSNP
rs1445794527 762 dbSNP
rs1383356328 766 dbSNP
rs774563738 766 dbSNP
rs566559606 773 dbSNP
rs897162958 779 dbSNP
rs971802846 785 dbSNP
rs1394697422 788 dbSNP
rs1160064794 792 dbSNP
rs3749231 795 dbSNP
rs181138555 796 dbSNP
rs567968151 797 dbSNP
rs1351850055 806 dbSNP
rs1180672325 813 dbSNP
rs992901565 816 dbSNP
rs1311335950 817 dbSNP
rs1007493748 824 dbSNP
rs1216054530 826 dbSNP
rs1489036141 831 dbSNP
rs1283448203 835 dbSNP
rs1239111385 837 dbSNP
rs1359917622 841 dbSNP
rs1246462498 843 dbSNP
rs1314745803 852 dbSNP
rs915601830 854 dbSNP
rs1018431021 856 dbSNP
rs1289463574 863 dbSNP
rs948961671 872 dbSNP
rs767645463 873 dbSNP
rs1341189971 874 dbSNP
rs1205857117 876 dbSNP
rs144189535 880 dbSNP
rs934826780 888 dbSNP
rs1425662622 900 dbSNP
rs989895430 903 dbSNP
rs1484102685 914 dbSNP
rs1163284640 930 dbSNP
rs756048405 934 dbSNP
rs1423806810 938 dbSNP
rs1420870435 941 dbSNP
rs550719068 943 dbSNP
rs901245787 944 dbSNP
rs998317256 947 dbSNP
rs1198834600 951 dbSNP
rs1050170976 952 dbSNP
rs1490443640 954 dbSNP
rs1255500815 955 dbSNP
rs568883777 965 dbSNP
rs1007451879 979 dbSNP
rs764071964 980 dbSNP
rs967050626 981 dbSNP
rs530165393 991 dbSNP
rs981107960 993 dbSNP
rs1220492776 997 dbSNP
rs534657914 1005 dbSNP
rs1405846995 1011 dbSNP
rs758787821 1012 dbSNP
rs186644803 1014 dbSNP
rs1457727550 1016 dbSNP
rs1355586123 1023 dbSNP
rs993732042 1025 dbSNP
rs1449215752 1027 dbSNP
rs1169826301 1028 dbSNP
rs1372978633 1030 dbSNP
rs530663811 1032 dbSNP
rs148713930 1033 dbSNP
rs1480526435 1034 dbSNP
rs909049254 1035 dbSNP
rs1402214519 1036 dbSNP
rs1397486094 1039 dbSNP
rs371490781 1050 dbSNP
rs533720065 1053 dbSNP
rs556102255 1054 dbSNP
rs1224222213 1056 dbSNP
rs550381706 1056 dbSNP
rs78781771 1057 dbSNP
rs891398908 1059 dbSNP
rs1464583022 1061 dbSNP
rs1299501651 1062 dbSNP
rs879136704 1063 dbSNP
rs1169258133 1065 dbSNP
rs1469895304 1067 dbSNP
rs1345675155 1070 dbSNP
rs969715606 1073 dbSNP
rs1255550875 1079 dbSNP
rs1483609451 1080 dbSNP
rs1180415067 1083 dbSNP
rs560675987 1086 dbSNP
rs1237500743 1091 dbSNP
rs780914527 1091 dbSNP
rs1347251280 1097 dbSNP
rs1011723636 1105 dbSNP
rs1020066298 1112 dbSNP
rs142289014 1116 dbSNP
rs1311996382 1123 dbSNP
rs1445030744 1124 dbSNP
rs934963238 1127 dbSNP
rs989381874 1128 dbSNP
rs922816527 1131 dbSNP
rs1337986217 1134 dbSNP
rs934054299 1142 dbSNP
rs1035356514 1145 dbSNP
rs868172706 1146 dbSNP
rs958914488 1160 dbSNP
rs1467112202 1164 dbSNP
rs1286801562 1165 dbSNP
rs1437629727 1173 dbSNP
rs991426029 1175 dbSNP
rs889753347 1183 dbSNP
rs941878847 1185 dbSNP
rs758117974 1197 dbSNP
rs779469576 1211 dbSNP
rs1254248835 1213 dbSNP
rs578097628 1218 dbSNP
rs1200079694 1226 dbSNP
rs1486284652 1227 dbSNP
rs941350966 1228 dbSNP
rs1238364881 1229 dbSNP
rs1353500424 1241 dbSNP
rs918693676 1246 dbSNP
rs545526196 1258 dbSNP
rs1247707766 1259 dbSNP
rs1341723686 1268 dbSNP
rs560211252 1269 dbSNP
rs1394948392 1270 dbSNP
rs1368506713 1275 dbSNP
rs1218631029 1276 dbSNP
rs1299681800 1279 dbSNP
rs899077534 1291 dbSNP
rs1359712734 1295 dbSNP
rs148253829 1300 dbSNP
rs1473769947 1305 dbSNP
rs1366661421 1310 dbSNP
rs1312886528 1314 dbSNP
rs1429220997 1321 dbSNP
rs527683047 1330 dbSNP
rs1214769754 1341 dbSNP
rs1380782458 1346 dbSNP
rs1266261164 1351 dbSNP
rs1293025269 1353 dbSNP
rs1212015845 1355 dbSNP
rs1354774902 1356 dbSNP
rs1328769163 1357 dbSNP
rs1284159054 1362 dbSNP
rs1026553702 1365 dbSNP
rs1340653765 1368 dbSNP
rs1279668550 1370 dbSNP
rs191485714 1371 dbSNP
rs1487702175 1372 dbSNP
rs561666263 1373 dbSNP
rs1323904051 1374 dbSNP
rs1406884628 1376 dbSNP
rs1014398955 1385 dbSNP
rs754653247 1389 dbSNP
rs1425953632 1390 dbSNP
rs73045940 1391 dbSNP
rs1435387316 1401 dbSNP
rs867950280 1403 dbSNP
rs372545381 1404 dbSNP
rs1201406552 1405 dbSNP
rs532369192 1408 dbSNP
rs1289768195 1412 dbSNP
rs1032678760 1415 dbSNP
rs956467990 1425 dbSNP
rs780723774 1427 dbSNP
rs1196930398 1431 dbSNP
rs989103628 1443 dbSNP
rs1457449694 1445 dbSNP
rs902970911 1452 dbSNP
rs771301996 1454 dbSNP
rs1392080074 1456 dbSNP
rs1316846556 1459 dbSNP
rs541443163 1460 dbSNP
rs1035810302 1461 dbSNP
rs1329175457 1464 dbSNP
rs1415604028 1469 dbSNP
rs1447493848 1469 dbSNP
rs1293855861 1479 dbSNP
rs922731749 1485 dbSNP
rs59843451 1492 dbSNP
rs1426078512 1500 dbSNP
rs1174586769 1509 dbSNP
rs985509774 1511 dbSNP
rs1389544820 1512 dbSNP
rs879013525 1515 dbSNP
rs1179801241 1527 dbSNP
rs911303907 1533 dbSNP
rs1459437342 1541 dbSNP
rs1328573656 1545 dbSNP
rs73185726 1555 dbSNP
rs1196168187 1563 dbSNP
rs541657437 1564 dbSNP
rs1320338032 1567 dbSNP
rs1038363514 1568 dbSNP
rs1221339748 1576 dbSNP
rs897182992 1583 dbSNP
rs539251727 1586 dbSNP
rs551501960 1604 dbSNP
rs1240603918 1608 dbSNP
rs1047659896 1609 dbSNP
rs1329252054 1628 dbSNP
rs1446106429 1634 dbSNP
rs895600181 1637 dbSNP
rs1359861203 1638 dbSNP
rs1336400097 1639 dbSNP
rs1413043003 1648 dbSNP
rs1014050007 1651 dbSNP
rs1424739616 1655 dbSNP
rs1159558746 1656 dbSNP
rs777811082 1661 dbSNP
rs1378955096 1668 dbSNP
rs1178609188 1672 dbSNP
rs1480022985 1675 dbSNP
rs749241229 1685 dbSNP
rs183796532 1701 dbSNP
rs1211628181 1702 dbSNP
rs1472618116 1706 dbSNP
rs1033076293 1707 dbSNP
rs1217005450 1707 dbSNP
rs1355651850 1708 dbSNP
rs1306952184 1715 dbSNP
rs1411218588 1716 dbSNP
rs146309932 1717 dbSNP
rs1445921950 1718 dbSNP
rs1358762505 1734 dbSNP
rs986906016 1738 dbSNP
rs1165232178 1740 dbSNP
rs1299057008 1743 dbSNP
rs201753467 1748 dbSNP
rs764041926 1750 dbSNP
rs1421871162 1762 dbSNP
rs1359101603 1769 dbSNP
rs568563252 1770 dbSNP
rs770701758 1772 dbSNP
rs1416591726 1774 dbSNP
rs955850347 1777 dbSNP
rs753827511 1778 dbSNP
rs912609594 1781 dbSNP
rs374180080 1797 dbSNP
rs761828489 1806 dbSNP
rs1283697147 1809 dbSNP
rs187852350 1816 dbSNP
rs914856800 1822 dbSNP
rs1291978165 1823 dbSNP
rs1226631580 1825 dbSNP
rs1354957214 1834 dbSNP
rs1307324656 1835 dbSNP
rs1279072390 1837 dbSNP
rs1350003507 1838 dbSNP
rs962776978 1844 dbSNP
rs1297896640 1850 dbSNP
rs974169498 1857 dbSNP
rs918561902 1859 dbSNP
rs929997672 1861 dbSNP
rs1403067841 1863 dbSNP
rs1290248819 1864 dbSNP
rs1416618364 1870 dbSNP
rs1193921065 1871 dbSNP
rs778626835 1873 dbSNP
rs917164475 1880 dbSNP
rs1185674677 1889 dbSNP
rs1227901069 1893 dbSNP
rs377388432 1894 dbSNP
rs1313892935 1895 dbSNP
rs191213854 1897 dbSNP
rs1334233965 1903 dbSNP
rs538564178 1907 dbSNP
rs1220547990 1908 dbSNP
rs1323878701 1910 dbSNP
rs1003421099 1915 dbSNP
rs1274509551 1916 dbSNP
rs1295151045 1924 dbSNP
rs1483643158 1926 dbSNP
rs950007389 1927 dbSNP
rs1292288587 1928 dbSNP
rs1044187441 1936 dbSNP
rs556568123 1938 dbSNP
rs999872922 1939 dbSNP
rs139586936 1941 dbSNP
rs1472263575 1946 dbSNP
rs1169372050 1948 dbSNP
rs545152527 1951 dbSNP
rs1433526616 1953 dbSNP
rs375598414 1957 dbSNP
rs563451752 1957 dbSNP
rs891415184 1962 dbSNP
rs144304617 1963 dbSNP
rs963297713 1975 dbSNP
rs78611225 1984 dbSNP
rs1167930023 1985 dbSNP
rs1371123399 1986 dbSNP
rs1026148848 1989 dbSNP
rs954575560 1989 dbSNP
rs1330994762 1998 dbSNP
rs1250938273 2010 dbSNP
rs868144645 2011 dbSNP
rs751128953 2012 dbSNP
rs987688254 2019 dbSNP
rs1299573534 2020 dbSNP
rs1357437013 2021 dbSNP
rs1234026784 2023 dbSNP
rs1447666660 2023 dbSNP
rs955589859 2028 dbSNP
rs1378252187 2043 dbSNP
rs1284975851 2046 dbSNP
rs1007177010 2049 dbSNP
rs1381843945 2050 dbSNP
rs1448327742 2063 dbSNP
rs1393745875 2066 dbSNP
rs1297235718 2068 dbSNP
rs912671976 2078 dbSNP
rs964464386 2087 dbSNP
rs1173643124 2103 dbSNP
rs1453599622 2104 dbSNP
rs1380816218 2126 dbSNP
rs867117848 2132 dbSNP
rs1180474573 2135 dbSNP
rs1437899352 2137 dbSNP
rs962891651 2144 dbSNP
rs76237494 2147 dbSNP
rs1201122063 2149 dbSNP
rs918688230 2161 dbSNP
rs951579372 2162 dbSNP
rs754517161 2165 dbSNP
rs947333915 2167 dbSNP
rs1042002325 2168 dbSNP
rs369521982 2169 dbSNP
rs1231170717 2170 dbSNP
rs1312061726 2171 dbSNP
rs1238700081 2173 dbSNP
rs146593301 2179 dbSNP
rs1396135097 2180 dbSNP
rs917932343 2184 dbSNP
rs368425760 2185 dbSNP
rs374084865 2193 dbSNP
rs949955388 2196 dbSNP
rs780514551 2203 dbSNP
rs1160370567 2205 dbSNP
rs1044304071 2206 dbSNP
rs776666956 2207 dbSNP
rs1188286140 2215 dbSNP
rs927105024 2219 dbSNP
rs935837962 2220 dbSNP
rs1187554803 2223 dbSNP
rs1451263016 2225 dbSNP
rs1170741293 2226 dbSNP
rs1288524766 2227 dbSNP
rs1214907311 2230 dbSNP
rs1350533955 2232 dbSNP
rs749855324 2237 dbSNP
rs1423228900 2241 dbSNP
rs1244854143 2246 dbSNP
rs1413944127 2251 dbSNP
rs1054731731 2253 dbSNP
rs1291051088 2268 dbSNP
rs1408599387 2279 dbSNP
rs141065562 2285 dbSNP
rs890350902 2300 dbSNP
rs183379707 2301 dbSNP
rs1017848799 2302 dbSNP
rs1398768950 2303 dbSNP
rs964165551 2306 dbSNP
rs533158049 2307 dbSNP
rs1273560031 2321 dbSNP
rs890811389 2322 dbSNP
rs11919795 2326 dbSNP
rs1164464962 2330 dbSNP
rs1018542851 2332 dbSNP
rs1219339450 2340 dbSNP
rs566593255 2346 dbSNP
rs1446831036 2349 dbSNP
rs779292985 2355 dbSNP
rs1268628787 2359 dbSNP
rs1026270843 2364 dbSNP
rs1212219520 2383 dbSNP
rs527411079 2389 dbSNP
rs1326659867 2390 dbSNP
rs1207640329 2392 dbSNP
rs1232156473 2392 dbSNP
rs1318122312 2397 dbSNP
rs549082715 2402 dbSNP
rs992678983 2403 dbSNP
rs746210423 2404 dbSNP
rs1388509372 2406 dbSNP
rs567294531 2411 dbSNP
rs1466080606 2415 dbSNP
rs1164248280 2418 dbSNP
rs1466225182 2424 dbSNP
rs149847524 2428 dbSNP
rs924909533 2430 dbSNP
rs1166412405 2433 dbSNP
rs1475288758 2435 dbSNP
rs556820012 2437 dbSNP
rs1201479048 2443 dbSNP
rs1467476643 2456 dbSNP
rs1252957649 2459 dbSNP
rs979949371 2460 dbSNP
rs1457862555 2467 dbSNP
rs1259557884 2480 dbSNP
rs927219456 2484 dbSNP
rs1338492546 2485 dbSNP
rs186634340 2491 dbSNP
rs993043160 2507 dbSNP
rs1235179057 2508 dbSNP
rs1368631735 2509 dbSNP
rs571807912 2510 dbSNP
rs1325191603 2515 dbSNP
rs1447563665 2526 dbSNP
rs1402630924 2527 dbSNP
rs1431451694 2528 dbSNP
rs1455905933 2536 dbSNP
rs1409544588 2537 dbSNP
rs192748009 2541 dbSNP
rs140279830 2565 dbSNP
rs866574127 2565 dbSNP
rs948848999 2589 dbSNP
rs989981422 2593 dbSNP
rs1179865941 2594 dbSNP
rs10937163 2595 dbSNP
rs141406009 2598 dbSNP
rs1436821051 2600 dbSNP
rs928998537 2600 dbSNP
rs1047836374 2603 dbSNP
rs1212719014 2612 dbSNP
rs188382259 2613 dbSNP
rs1051311449 2632 dbSNP
rs890758562 2635 dbSNP
rs942353544 2636 dbSNP
rs1240858556 2639 dbSNP
rs1379037897 2640 dbSNP
rs373593335 2643 dbSNP
rs898744937 2649 dbSNP
rs1009229029 2651 dbSNP
rs773655130 2659 dbSNP
rs554759246 2664 dbSNP
rs1348084361 2667 dbSNP
rs996181916 2673 dbSNP
rs1017483861 2674 dbSNP
rs576385937 2682 dbSNP
rs1421999437 2683 dbSNP
rs192875821 2684 dbSNP
rs1330717197 2706 dbSNP
rs1174918649 2709 dbSNP
rs760742309 2718 dbSNP
rs763429333 2719 dbSNP
rs1025016968 2723 dbSNP
rs1484559360 2737 dbSNP
rs969325923 2741 dbSNP
rs1452112952 2752 dbSNP
rs1032081076 2753 dbSNP
rs980737555 2755 dbSNP
rs1032329473 2764 dbSNP
rs1318612323 2778 dbSNP
rs1282094370 2782 dbSNP
rs960357416 2783 dbSNP
rs866377677 2787 dbSNP
rs1471638791 2788 dbSNP
rs1413235381 2802 dbSNP
rs916130677 2803 dbSNP
rs1299116325 2808 dbSNP
rs1413017423 2813 dbSNP
rs948902868 2817 dbSNP
rs1402263721 2823 dbSNP
rs1455498597 2824 dbSNP
rs1343923007 2826 dbSNP
rs1161844447 2828 dbSNP
rs973524636 2835 dbSNP
rs957298071 2839 dbSNP
rs562813886 2843 dbSNP
rs200206587 2846 dbSNP
rs745971196 2846 dbSNP
rs768143265 2846 dbSNP
rs1000299976 2850 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 1857.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' guggucgaucGGAGUGg 5'
                    |||||| 
Target 5' auaauaccuaCCUCACa 3'
 		11 - 27
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000313143.3 | 3UTR | AAUGAUGAUAAUAAUACCUACCUCACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
74 hsa-miR-4316 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080624 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 2
MIRT095088 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT123331 CALU calumenin 2 2
MIRT154964 RRM2 ribonucleotide reductase regulatory subunit M2 2 2
MIRT370850 TGFBR2 transforming growth factor beta receptor 2 2 2
MIRT442955 SGCD sarcoglycan delta 2 2
MIRT448240 ZNF774 zinc finger protein 774 2 2
MIRT451710 OLR1 oxidized low density lipoprotein receptor 1 2 2
MIRT452072 ATP6V0B ATPase H+ transporting V0 subunit b 2 2
MIRT455665 GLO1 glyoxalase I 2 2
MIRT460354 TXNDC16 thioredoxin domain containing 16 2 2
MIRT461908 NECAB3 N-terminal EF-hand calcium binding protein 3 2 2
MIRT462047 HOXC13 homeobox C13 2 2
MIRT462735 EFNB1 ephrin B1 2 2
MIRT463409 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT464952 TWIST1 twist family bHLH transcription factor 1 2 2
MIRT465052 TSR1 TSR1, ribosome maturation factor 2 2
MIRT467549 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 2 4
MIRT470226 PRRC2A proline rich coiled-coil 2A 2 2
MIRT474081 LMBR1L limb development membrane protein 1 like 2 2
MIRT474481 KLHDC8B kelch domain containing 8B 2 2
MIRT474704 KIF3A kinesin family member 3A 2 2
MIRT474897 KCTD21 potassium channel tetramerization domain containing 21 2 2
MIRT475203 IL2RB interleukin 2 receptor subunit beta 2 2
MIRT477664 EFHD2 EF-hand domain family member D2 2 2
MIRT477775 E2F3 E2F transcription factor 3 2 2
MIRT477940 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478224 DDX52 DExD-box helicase 52 2 2
MIRT479904 CCDC117 coiled-coil domain containing 117 2 2
MIRT480639 BSCL2 BSCL2, seipin lipid droplet biogenesis associated 2 2
MIRT482435 ADM adrenomedullin 2 10
MIRT483908 GNB1L G protein subunit beta 1 like 2 2
MIRT484161 FAM71B family with sequence similarity 71 member B 2 2
MIRT484405 SNX19 sorting nexin 19 2 2
MIRT485426 LASP1 LIM and SH3 protein 1 2 2
MIRT489788 KRT80 keratin 80 2 4
MIRT490813 ASB1 ankyrin repeat and SOCS box containing 1 2 4
MIRT491176 LAMA5 laminin subunit alpha 5 2 2
MIRT491573 HSDL1 hydroxysteroid dehydrogenase like 1 2 2
MIRT492633 PLXNA1 plexin A1 2 2
MIRT492984 NAV1 neuron navigator 1 2 2
MIRT496441 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT501829 NCOA3 nuclear receptor coactivator 3 2 2
MIRT502165 KIAA0195 transmembrane protein 94 2 2
MIRT508652 DIABLO diablo IAP-binding mitochondrial protein 2 4
MIRT509554 ACTG1 actin gamma 1 2 4
MIRT520033 YOD1 YOD1 deubiquitinase 2 6
MIRT523969 DVL3 dishevelled segment polarity protein 3 2 2
MIRT526150 KIAA1456 KIAA1456 2 2
MIRT530330 ARHGAP1 Rho GTPase activating protein 1 2 2
MIRT539985 SLC24A4 solute carrier family 24 member 4 2 4
MIRT540851 NUP155 nucleoporin 155 2 2
MIRT542326 LIMD1 LIM domains containing 1 2 2
MIRT558908 CBX5 chromobox 5 2 2
MIRT563663 SMC4 structural maintenance of chromosomes 4 2 2
MIRT565433 SURF4 surfeit 4 2 2
MIRT567773 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT615573 NCS1 neuronal calcium sensor 1 2 2
MIRT627336 TTLL7 tubulin tyrosine ligase like 7 2 2
MIRT632965 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT634307 SNTN sentan, cilia apical structure protein 2 2
MIRT641569 RAX retina and anterior neural fold homeobox 2 2
MIRT660509 ARL5A ADP ribosylation factor like GTPase 5A 2 2
MIRT662703 C10orf111 chromosome 10 open reading frame 111 2 4
MIRT663214 ZNF277 zinc finger protein 277 2 2
MIRT665318 YIPF4 Yip1 domain family member 4 2 2
MIRT695264 CD209 CD209 molecule 2 2
MIRT696231 LIN9 lin-9 DREAM MuvB core complex component 2 2
MIRT698867 SRPR SRP receptor alpha subunit 2 2
MIRT702700 IPO9 importin 9 2 2
MIRT704236 DHDDS dehydrodolichyl diphosphate synthase subunit 2 2
MIRT704935 CCDC120 coiled-coil domain containing 120 2 2
MIRT724285 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 2
MIRT735579 VEGFA vascular endothelial growth factor A 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4316 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-miR-4316 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4316 Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)

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