miRTarBase - #MIRT524335


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pre-miRNA Information
pre-miRNA hsa-mir-216b   
Genomic Coordinates chr2: 56000714 - 56000795
Description Homo sapiens miR-216b stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-216b-3p
Sequence 49| ACACACUUACCCGUAGAGAUUCUA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 9 2 - 56000739 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1032185572 4 dbSNP
rs1291886633 6 dbSNP
rs1195180466 10 dbSNP
rs761473579 10 dbSNP
rs751204276 12 dbSNP
rs368125248 13 dbSNP
rs755646560 13 dbSNP
rs1307586870 14 dbSNP
rs907200088 16 dbSNP
rs763696104 22 dbSNP
rs762699560 24 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B5PHM2 miR-216b Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma MiRNA qPCR analyses
Gene Information
Gene Symbol CRK   
Synonyms CRKII, p38
Description CRK proto-oncogene, adaptor protein
Transcript NM_005206   
Other Transcripts NM_016823   
Expression
Putative miRNA Targets on CRK
3'UTR of CRK
(miRNA target sites are highlighted)		 
>CRK|NM_005206|3'UTR
   1 GCTGGTAAAGGTTACGAAGATTAATGTGAGTGGTCAGTGGGAAGGGGAGTGTAATGGCAAACGAGGTCACTTCCCATTCA
  81 CACATGTCCGTCTGCTGGATCAACAGAATCCCGATGAGGACTTCAGCTGAGTATAGTTCAACAGTTTTGCTGACAGATGG
 161 GAACAATCTTTTTTTTTTTTTTCCAACTGCCATCTATACAATTTTCTTACAGATGTCAAAAGCAGTCTAGTTTATATAAG
 241 CATTCTGTTACCTGTGATATTTTTTAGACTGAACTGCTCCATTCCTAGTCTTAATTACCATATTCAGGGTACGAACTGGA
 321 GGGCTTGTGTGTTAGCTTCTGAATTGGCAATTGGAGGCGGTAGTGGTCGTGCCTGTGTGTATCAGAAGGGATAGGTATCT
 401 TGCCTCCTTTCTCTCAGGCAGTGCAAATCACCCTGTGGAAAACCGATGGACAGGAAGGAGTGTTACACACTGCTTACCCT
 481 GATTTATTCAGTGGTTTTGTTTTCATTCTGGAACCATACTATCAAATGGCGACAGACTGTTCCGTTCCACCCCCGTGAAG
 561 TAATCATGCACCGTGTGAATAGTATCAAGCAGGATTGCTTTCATTGTATGGAGCATGACCAGCGTGTGACTCATTCTGAC
 641 ATTTCAGATCCTAAGAATTCTAAGAACACTACTAGAAGCATTTGTTCCCTCCTAGTCAATGCTTCATACTTTTTCTTGGG
 721 ATTCTTTTAGCCCTTGACATTCTTGTCCCCCAAACCTGTAAGTAGGTGAATTCCTAAGATAAGTGTGTATTTTCATTCCA
 801 GGTGAAAAGCAGGATGTACCGAGCACTTTATTCAGTGCATAGCTTTAAGCCAGTGTTGGATTCACTAAGTGGACAGCCAG
 881 TCTCCCAGCTCTCTGCCTTCCCCAAAAGGGTCGTAGTAGGTCACCCTTCTACAGCAGCTAACTAGAGTCCTAACTAATGG
 961 GATCCAGCAGGGCCATTTCTCCAGAGGGCCAGTATCCTATTAGGAGACTCTTGGAATTCTTAGGTTCTACTCAAGAGTGG
1041 AAGGACCAATCACCTCTGATATTCTGTGGAAGGTTTTGGGGTCAAATTCTGCCCTCTGCATTCTGTGCAACTTGTATAAA
1121 AGTCAAGTTAGTATTACATGAATTTGGGGTAGGGTTAGTGCTTTGAAAAAATGTTGAACCGGCTGGGCGCGGTGGCTCAC
1201 GTCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATAG
1281 TGAAACCCCATCTCTGCTAAAGATATAAAAAATTAGCCCGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGG
1361 CTGAGGCAGGAGAATTGCTTCAACCTGGGAGGTGGAGGCTGCAGTGAGCCGAGATCGCACCACTGCGTTCCAGCCTGAGC
1441 GACAGGGCAAGACTCAGTCTCAAAAAAAAAAAAAAGGAAAAAAAAAAGAAAAAAAAATGTTGAACCAATTGTGAATTACT
1521 TATGTATTATTCATTTCTCATGGGGAGAGTAATGCTGTTGAAGAACATTACATTGTAAACTGCCTTCATTTTTGGCTCTT
1601 TGTTTATGTTCAGGTTTAGTTTACAAACCCATTTAAGTATGGAATGATTTATATGGGGTCAGGTGCTCCACAAAATAGAC
1681 CTATGAGACCAAAAATGACCTAGGCTATTTAGACGACAGCATGAAACTTCCACGTTAGTTCTCAGTCTATAAAGGCACTT
1761 ACCGGTCTCTGGTGTGGTATGACCAATAGAAACACCTTATAGTTTGCTTTGGACCTCATTTTGGAAAAATAATCTGCCTT
1841 TCTAATTGTTCTGCATAGGTTAAAATGATAAATTTACATTCTTTGAACCTATACCAGATTGTGGTGTCCGAGTGACCGGC
1921 ACACTGTCTGACACACAGTCAGTGTGCACGTATTTGTCTGAGTGAATGAGGAGACCTGAGAAACCGGTGACGTGGCACAG
2001 GGAAGCCAGCTGGCCCAGGATTCCGTACATGGCCGCAAGCAGACTAACGCGTTGACGCTAATTTAATGTATTTTACCTCA
2081 CACTAAGGTCATGCTTGATAAAGACGTTAAACTCAACTTGTAAAATGGTAGCCCAGTGCTATGCACAGAGTGGGTGCTCA
2161 TTAGTGTTGAATGAACACATTTGTAATACTACATGTAATTCCATCTGACTGCTTTGTTAAATTTTCAGTTAGAACGTAGA
2241 TACTGTAAAGTCCACACACACATTAAATCTTGTTTTCCTGAAAGTATGGC
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' auCUUAGAGAUGCCCAUUCACACa 5'
            ||||: |||  | |||||||| 
Target 5' gtGAATTCCTA-AGATAAGTGTGt 3'
 766 - 788 169.00 -14.90
2 
miRNA  3' aucUUAG---AGAUGCCCAUUCACACa 5'
             ||||   |:| |  | |||| || 
Target 5' ttaAATCTTGTTTTCCTGAAAGTATGg 3'
 2263 - 2289 125.00 -5.24
3 
miRNA  3' auCUUAGAGAUGCCCA------UUCACACa 5'
            |||| |||  || |      ||| ||| 
Target 5' tgGAAT-TCTTAGGTTCTACTCAAGAGTGg 3'
 1012 - 1040 123.00 -10.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM6002415 15 COSMIC
COSM472319 22 COSMIC
COSM2154432 65 COSMIC
COSM2154431 67 COSMIC
COSM2154448 68 COSMIC
COSM2154449 69 COSMIC
COSM2154447 70 COSMIC
COSM2154419 71 COSMIC
COSM8071170 74 COSMIC
COSM9205317 88 COSMIC
COSM4748490 98 COSMIC
COSM9205316 111 COSMIC
COSM8864295 124 COSMIC
COSN30518664 156 COSMIC
COSN32076785 156 COSMIC
COSN30505834 159 COSMIC
COSN30513410 166 COSMIC
COSN30490379 167 COSMIC
COSN20113238 168 COSMIC
COSN2375351 169 COSMIC
COSN2526112 169 COSMIC
COSN27410174 169 COSMIC
COSN19666227 182 COSMIC
COSN2375350 183 COSMIC
COSN30483745 227 COSMIC
COSN30483637 228 COSMIC
COSN31553920 277 COSMIC
COSN18741203 291 COSMIC
COSN31543852 312 COSMIC
COSN31556525 530 COSMIC
COSN31521564 554 COSMIC
COSN31565630 572 COSMIC
COSN31961260 702 COSMIC
COSN30174444 705 COSMIC
COSN31542882 741 COSMIC
COSN1193137 975 COSMIC
COSN31484560 981 COSMIC
COSN24282965 1137 COSMIC
COSN30541376 1191 COSMIC
COSN15244265 1199 COSMIC
COSN24731964 1272 COSMIC
COSN6650935 1319 COSMIC
COSN15016792 1320 COSMIC
COSN20172636 1416 COSMIC
COSN24733021 1478 COSMIC
COSN20254887 1556 COSMIC
COSN6650932 1640 COSMIC
COSN25500017 1657 COSMIC
COSN32093385 1914 COSMIC
COSN1713842 2065 COSMIC
COSN32061477 2346 COSMIC
COSN6650930 2520 COSMIC
COSN7160222 2748 COSMIC
COSN16178840 2816 COSMIC
COSN25753958 2938 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs149078123 1 dbSNP
rs1460550029 5 dbSNP
rs954838481 15 dbSNP
rs1363339648 16 dbSNP
rs145094200 23 dbSNP
rs778437493 34 dbSNP
rs1260863082 41 dbSNP
rs1398231816 45 dbSNP
rs756685839 46 dbSNP
rs748279653 51 dbSNP
rs781401346 54 dbSNP
rs755037548 56 dbSNP
rs751763519 57 dbSNP
rs766559218 63 dbSNP
rs758145321 67 dbSNP
rs1257672960 70 dbSNP
rs750209037 79 dbSNP
rs1477228518 80 dbSNP
rs746234297 85 dbSNP
rs765221724 89 dbSNP
rs761704148 90 dbSNP
rs1421174730 93 dbSNP
rs963953252 98 dbSNP
rs371718957 103 dbSNP
rs1278918643 108 dbSNP
rs150365260 112 dbSNP
rs140388019 113 dbSNP
rs368713980 115 dbSNP
rs775008230 116 dbSNP
rs146555797 126 dbSNP
rs941775690 131 dbSNP
rs566945238 132 dbSNP
rs184468514 134 dbSNP
rs770473405 139 dbSNP
rs1215557190 141 dbSNP
rs1279976408 148 dbSNP
rs1346359886 150 dbSNP
rs1047371163 152 dbSNP
rs748688807 154 dbSNP
rs1213726332 155 dbSNP
rs200149433 156 dbSNP
rs768626621 158 dbSNP
rs1445964605 159 dbSNP
rs747056266 161 dbSNP
rs373966581 164 dbSNP
rs758645482 166 dbSNP
rs1429345418 167 dbSNP
rs1177697204 168 dbSNP
rs1431087124 169 dbSNP
rs750255685 171 dbSNP
rs1475497584 173 dbSNP
rs1190932500 180 dbSNP
rs1192783499 182 dbSNP
rs1053352628 183 dbSNP
rs1400218021 183 dbSNP
rs1455421736 183 dbSNP
rs748614587 183 dbSNP
rs76288901 183 dbSNP
rs879010836 183 dbSNP
rs1404923337 184 dbSNP
rs934622580 185 dbSNP
rs181367214 186 dbSNP
rs1436016668 189 dbSNP
rs770442138 190 dbSNP
rs1302945520 201 dbSNP
rs925841263 204 dbSNP
rs1042719379 210 dbSNP
rs1381252538 210 dbSNP
rs1350535925 215 dbSNP
rs539335232 216 dbSNP
rs1202856963 217 dbSNP
rs1285672874 226 dbSNP
rs572039367 231 dbSNP
rs1447061857 236 dbSNP
rs1169051537 240 dbSNP
rs993453070 246 dbSNP
rs774655954 257 dbSNP
rs927439949 259 dbSNP
rs1465400679 261 dbSNP
rs865958835 269 dbSNP
rs980213749 274 dbSNP
rs61762271 281 dbSNP
rs763413960 301 dbSNP
rs1022105711 303 dbSNP
rs1366207030 306 dbSNP
rs1010251621 307 dbSNP
rs987221924 311 dbSNP
rs1457807292 312 dbSNP
rs954605335 313 dbSNP
rs1392493485 322 dbSNP
rs956201147 324 dbSNP
rs1335697978 331 dbSNP
rs1030250216 335 dbSNP
rs1258147912 344 dbSNP
rs1237594337 351 dbSNP
rs1196599353 353 dbSNP
rs866943333 359 dbSNP
rs535495662 361 dbSNP
rs963680821 363 dbSNP
rs1469503219 367 dbSNP
rs568498802 369 dbSNP
rs62089594 371 dbSNP
rs1016496590 372 dbSNP
rs1283699697 388 dbSNP
rs1038828685 397 dbSNP
rs773708842 404 dbSNP
rs1472971330 406 dbSNP
rs1164249756 407 dbSNP
rs1458508657 413 dbSNP
rs1334948566 415 dbSNP
rs1005948880 421 dbSNP
rs1463154622 424 dbSNP
rs887551495 426 dbSNP
rs112872338 443 dbSNP
rs142954537 444 dbSNP
rs1351591661 445 dbSNP
rs772889848 447 dbSNP
rs188661552 449 dbSNP
rs1803325 458 dbSNP
rs1365037314 459 dbSNP
rs1290835238 461 dbSNP
rs1256651070 465 dbSNP
rs1235528828 466 dbSNP
rs1245141834 470 dbSNP
rs1443455965 470 dbSNP
rs1240932131 479 dbSNP
rs1057417032 495 dbSNP
rs938903940 498 dbSNP
rs552838131 499 dbSNP
rs1052980209 504 dbSNP
rs999068831 505 dbSNP
rs1337259462 507 dbSNP
rs148981564 509 dbSNP
rs904450239 510 dbSNP
rs748666755 515 dbSNP
rs1042917623 516 dbSNP
rs943289044 517 dbSNP
rs1187322468 518 dbSNP
rs560643359 530 dbSNP
rs1051366750 531 dbSNP
rs933109348 538 dbSNP
rs927470947 543 dbSNP
rs547330797 544 dbSNP
rs1203316432 550 dbSNP
rs528886850 554 dbSNP
rs776046824 555 dbSNP
rs1304024513 559 dbSNP
rs1464128051 572 dbSNP
rs968845920 573 dbSNP
rs914669826 574 dbSNP
rs1324277618 580 dbSNP
rs545009461 582 dbSNP
rs1376679932 583 dbSNP
rs376063689 585 dbSNP
rs1241028661 589 dbSNP
rs1275007187 589 dbSNP
rs1346861332 594 dbSNP
rs145797873 597 dbSNP
rs909466388 603 dbSNP
rs1441219416 607 dbSNP
rs1486725166 611 dbSNP
rs1201065121 612 dbSNP
rs543105398 613 dbSNP
rs1041975 615 dbSNP
rs575769654 620 dbSNP
rs997417944 623 dbSNP
rs183931575 624 dbSNP
rs1041976 626 dbSNP
rs1017448687 630 dbSNP
rs1466132165 632 dbSNP
rs1006021017 638 dbSNP
rs1382340426 667 dbSNP
rs533245864 669 dbSNP
rs1026064199 671 dbSNP
rs1370026263 678 dbSNP
rs149908866 679 dbSNP
rs757982646 696 dbSNP
rs1305569757 701 dbSNP
rs1202198019 709 dbSNP
rs1234064626 715 dbSNP
rs139110929 716 dbSNP
rs553789646 718 dbSNP
rs535791681 721 dbSNP
rs1021407302 724 dbSNP
rs1056127030 733 dbSNP
rs192161161 736 dbSNP
rs1468357922 738 dbSNP
rs1192099282 740 dbSNP
rs556560428 741 dbSNP
rs58414824 742 dbSNP
rs61762272 746 dbSNP
rs889014687 747 dbSNP
rs147372165 750 dbSNP
rs1454860401 753 dbSNP
rs1306796969 756 dbSNP
rs1320865025 764 dbSNP
rs932952106 773 dbSNP
rs552774877 779 dbSNP
rs1368236066 783 dbSNP
rs1284011715 784 dbSNP
rs914722352 785 dbSNP
rs988944771 788 dbSNP
rs534402802 789 dbSNP
rs757222327 792 dbSNP
rs35409499 800 dbSNP
rs1230278609 815 dbSNP
rs909413913 820 dbSNP
rs567108669 821 dbSNP
rs189061840 828 dbSNP
rs980920754 830 dbSNP
rs530466005 835 dbSNP
rs1248877171 843 dbSNP
rs34970553 852 dbSNP
rs1489007203 853 dbSNP
rs540777039 854 dbSNP
rs573408956 874 dbSNP
rs1217894999 876 dbSNP
rs769067758 877 dbSNP
rs185435497 884 dbSNP
rs1159214121 885 dbSNP
rs1416728244 889 dbSNP
rs1459497087 898 dbSNP
rs1026555241 903 dbSNP
rs1350323554 910 dbSNP
rs549397331 913 dbSNP
rs1296431903 934 dbSNP
rs1436791979 941 dbSNP
rs1375380969 942 dbSNP
rs1411745587 944 dbSNP
rs766776261 946 dbSNP
rs1034740012 956 dbSNP
rs1354884893 960 dbSNP
rs193240256 961 dbSNP
rs749555955 967 dbSNP
rs1292251585 974 dbSNP
rs1322746267 975 dbSNP
rs1295867145 988 dbSNP
rs1418531022 994 dbSNP
rs979959950 1001 dbSNP
rs1161180900 1012 dbSNP
rs1484286147 1013 dbSNP
rs1412625030 1015 dbSNP
rs968092968 1019 dbSNP
rs1256265722 1045 dbSNP
rs763255570 1046 dbSNP
rs879545008 1049 dbSNP
rs1183280348 1052 dbSNP
rs1414042858 1062 dbSNP
rs1409179801 1066 dbSNP
rs1424206282 1081 dbSNP
rs563856294 1098 dbSNP
rs1044708391 1100 dbSNP
rs1356219476 1107 dbSNP
rs1172902928 1112 dbSNP
rs1021438190 1114 dbSNP
rs1312194344 1116 dbSNP
rs545551544 1122 dbSNP
rs1374963602 1138 dbSNP
rs1412985669 1140 dbSNP
rs947618506 1143 dbSNP
rs893332408 1146 dbSNP
rs1007324675 1147 dbSNP
rs773763835 1153 dbSNP
rs35482632 1155 dbSNP
rs765668002 1163 dbSNP
rs762046797 1164 dbSNP
rs1214357422 1167 dbSNP
rs187478611 1175 dbSNP
rs182886406 1180 dbSNP
rs943374191 1181 dbSNP
rs910548542 1188 dbSNP
rs56402707 1189 dbSNP
rs1237727410 1190 dbSNP
rs190276955 1191 dbSNP
rs1391855953 1197 dbSNP
rs61762273 1198 dbSNP
rs972323786 1200 dbSNP
rs1325296047 1201 dbSNP
rs374950565 1202 dbSNP
rs796455687 1203 dbSNP
rs1336179856 1205 dbSNP
rs887505980 1210 dbSNP
rs1430354837 1211 dbSNP
rs1287332973 1213 dbSNP
rs1367847908 1213 dbSNP
rs1229569648 1215 dbSNP
rs1303345213 1227 dbSNP
rs960535899 1228 dbSNP
rs1034771395 1229 dbSNP
rs1278782277 1231 dbSNP
rs1275912195 1233 dbSNP
rs1001952569 1234 dbSNP
rs921424897 1237 dbSNP
rs61762274 1239 dbSNP
rs1021954563 1243 dbSNP
rs975230246 1249 dbSNP
rs756247480 1258 dbSNP
rs746054555 1264 dbSNP
rs1192730103 1270 dbSNP
rs1011855273 1271 dbSNP
rs893396987 1276 dbSNP
rs918177666 1278 dbSNP
rs1478937248 1280 dbSNP
rs1173079998 1287 dbSNP
rs1426048377 1290 dbSNP
rs1057159632 1294 dbSNP
rs746536939 1303 dbSNP
rs577375993 1306 dbSNP
rs935590818 1309 dbSNP
rs1436321121 1314 dbSNP
rs1334627527 1317 dbSNP
rs1126457 1319 dbSNP
rs1421841030 1320 dbSNP
rs1275929317 1321 dbSNP
rs182863103 1322 dbSNP
rs1040473186 1323 dbSNP
rs1269659936 1328 dbSNP
rs968123523 1329 dbSNP
rs943445969 1331 dbSNP
rs910578057 1334 dbSNP
rs61762275 1335 dbSNP
rs370075646 1345 dbSNP
rs1232212356 1354 dbSNP
rs953176814 1355 dbSNP
rs555180776 1363 dbSNP
rs1414475171 1366 dbSNP
rs1458016574 1373 dbSNP
rs536525901 1379 dbSNP
rs1180142210 1382 dbSNP
rs745487570 1384 dbSNP
rs1389074370 1385 dbSNP
rs1407412237 1392 dbSNP
rs551520928 1394 dbSNP
rs569557897 1399 dbSNP
rs572774661 1400 dbSNP
rs1238530013 1404 dbSNP
rs1206042899 1408 dbSNP
rs778495014 1410 dbSNP
rs919176452 1411 dbSNP
rs1289614896 1414 dbSNP
rs752637820 1416 dbSNP
rs971967919 1417 dbSNP
rs1270853830 1420 dbSNP
rs190675717 1426 dbSNP
rs927775862 1427 dbSNP
rs980544179 1440 dbSNP
rs141773136 1441 dbSNP
rs1454427990 1442 dbSNP
rs1015026317 1443 dbSNP
rs1366887283 1448 dbSNP
rs1473993956 1454 dbSNP
rs982460495 1454 dbSNP
rs1164126566 1455 dbSNP
rs1005865580 1456 dbSNP
rs1428451503 1457 dbSNP
rs1330381098 1459 dbSNP
rs1466357980 1460 dbSNP
rs887536991 1461 dbSNP
rs1413610189 1462 dbSNP
rs1162823558 1466 dbSNP
rs1022029453 1471 dbSNP
rs1341851350 1475 dbSNP
rs1245253559 1476 dbSNP
rs1296442356 1476 dbSNP
rs561230915 1476 dbSNP
rs1221324447 1477 dbSNP
rs1483436038 1477 dbSNP
rs1415234632 1478 dbSNP
rs1491213939 1478 dbSNP
rs1044800867 1479 dbSNP
rs1185975519 1483 dbSNP
rs1171096902 1488 dbSNP
rs1391276845 1488 dbSNP
rs1403925809 1488 dbSNP
rs1419582493 1488 dbSNP
rs1448014943 1488 dbSNP
rs951002009 1488 dbSNP
rs1317155284 1489 dbSNP
rs1396309849 1489 dbSNP
rs765104918 1489 dbSNP
rs1491461893 1490 dbSNP
rs1011001735 1492 dbSNP
rs896682792 1492 dbSNP
rs956364551 1494 dbSNP
rs1237983426 1496 dbSNP
rs1056623024 1497 dbSNP
rs1032340482 1498 dbSNP
rs1160760463 1498 dbSNP
rs1484276464 1498 dbSNP
rs536018335 1498 dbSNP
rs935607817 1498 dbSNP
rs749728700 1499 dbSNP
rs924193373 1499 dbSNP
rs570163620 1501 dbSNP
rs551849828 1504 dbSNP
rs999112372 1505 dbSNP
rs1454176801 1506 dbSNP
rs1174562039 1516 dbSNP
rs527419080 1519 dbSNP
rs1466084295 1520 dbSNP
rs1157658292 1522 dbSNP
rs1480782289 1522 dbSNP
rs75121449 1523 dbSNP
rs542035605 1527 dbSNP
rs1369956184 1530 dbSNP
rs1385072680 1532 dbSNP
rs1303280082 1544 dbSNP
rs879608204 1548 dbSNP
rs1314073447 1550 dbSNP
rs1040504038 1551 dbSNP
rs985548553 1555 dbSNP
rs1327259134 1566 dbSNP
rs187469301 1566 dbSNP
rs1248123448 1572 dbSNP
rs889215337 1587 dbSNP
rs777769894 1596 dbSNP
rs562786491 1597 dbSNP
rs1433296244 1599 dbSNP
rs1014812208 1606 dbSNP
rs930642082 1608 dbSNP
rs1409321965 1621 dbSNP
rs1391733136 1629 dbSNP
rs1005896631 1631 dbSNP
rs35262526 1631 dbSNP
rs1393511756 1632 dbSNP
rs1456180670 1635 dbSNP
rs1295247375 1638 dbSNP
rs1083 1640 dbSNP
rs1036723682 1641 dbSNP
rs1457546248 1648 dbSNP
rs939236548 1653 dbSNP
rs751719926 1654 dbSNP
rs1023300208 1655 dbSNP
rs1268979385 1657 dbSNP
rs1321519577 1666 dbSNP
rs1219770958 1670 dbSNP
rs980617817 1673 dbSNP
rs1418429306 1678 dbSNP
rs1205055107 1680 dbSNP
rs969181843 1685 dbSNP
rs1380199390 1687 dbSNP
rs1473268191 1700 dbSNP
rs538319727 1714 dbSNP
rs570796891 1715 dbSNP
rs989203982 1717 dbSNP
rs577308330 1720 dbSNP
rs1350413015 1722 dbSNP
rs1252298144 1724 dbSNP
rs1461473337 1730 dbSNP
rs1189110920 1732 dbSNP
rs1030657379 1733 dbSNP
rs1487932573 1734 dbSNP
rs999671416 1744 dbSNP
rs1368838216 1745 dbSNP
rs1411683281 1745 dbSNP
rs902771952 1747 dbSNP
rs868473801 1748 dbSNP
rs1043917998 1749 dbSNP
rs946966477 1751 dbSNP
rs61762276 1761 dbSNP
rs540356320 1762 dbSNP
rs765509891 1764 dbSNP
rs1007692473 1765 dbSNP
rs976332535 1771 dbSNP
rs1205206908 1783 dbSNP
rs1236543219 1787 dbSNP
rs889244816 1790 dbSNP
rs1482037849 1801 dbSNP
rs117239587 1806 dbSNP
rs1298830357 1807 dbSNP
rs1414348416 1810 dbSNP
rs559179006 1812 dbSNP
rs182249851 1817 dbSNP
rs1391897889 1826 dbSNP
rs61762277 1832 dbSNP
rs1023331213 1840 dbSNP
rs1036346195 1843 dbSNP
rs1446175490 1844 dbSNP
rs1159766730 1855 dbSNP
rs1455751954 1867 dbSNP
rs1228065499 1868 dbSNP
rs1296087110 1871 dbSNP
rs61762278 1877 dbSNP
rs547204130 1878 dbSNP
rs1228515265 1881 dbSNP
rs538992884 1888 dbSNP
rs570101189 1889 dbSNP
rs1237675283 1891 dbSNP
rs1464295781 1897 dbSNP
rs768992609 1898 dbSNP
rs551788277 1899 dbSNP
rs190943860 1910 dbSNP
rs1171922051 1912 dbSNP
rs1424598679 1917 dbSNP
rs935080817 1918 dbSNP
rs1261767032 1923 dbSNP
rs561524810 1926 dbSNP
rs1434834147 1928 dbSNP
rs1318885706 1931 dbSNP
rs1205653604 1936 dbSNP
rs1436553666 1938 dbSNP
rs775752892 1944 dbSNP
rs976402172 1947 dbSNP
rs964982500 1948 dbSNP
rs186275076 1949 dbSNP
rs548044993 1950 dbSNP
rs529907963 1952 dbSNP
rs953708188 1957 dbSNP
rs1206420912 1958 dbSNP
rs1269858725 1960 dbSNP
rs1198136596 1961 dbSNP
rs752804799 1961 dbSNP
rs562720325 1962 dbSNP
rs1027810597 1985 dbSNP
rs1192927029 1986 dbSNP
rs543190178 1991 dbSNP
rs533355239 1992 dbSNP
rs1037077619 2001 dbSNP
rs35340932 2005 dbSNP
rs1014987510 2009 dbSNP
rs569179940 2013 dbSNP
rs1285425087 2015 dbSNP
rs758994156 2017 dbSNP
rs550886493 2024 dbSNP
rs1323508461 2025 dbSNP
rs1318985450 2027 dbSNP
rs906491938 2028 dbSNP
rs907740823 2029 dbSNP
rs774004148 2034 dbSNP
rs770421427 2035 dbSNP
rs947942852 2045 dbSNP
rs930567399 2046 dbSNP
rs749173967 2048 dbSNP
rs1287652139 2050 dbSNP
rs893657394 2050 dbSNP
rs1269781153 2051 dbSNP
rs1178165659 2052 dbSNP
rs1180358423 2054 dbSNP
rs532484201 2057 dbSNP
rs1470718557 2059 dbSNP
rs61762279 2060 dbSNP
rs960364150 2066 dbSNP
rs181560142 2068 dbSNP
rs1448711648 2070 dbSNP
rs1035097095 2074 dbSNP
rs1407399146 2077 dbSNP
rs144568032 2082 dbSNP
rs149292052 2083 dbSNP
rs116852245 2088 dbSNP
rs1309504516 2097 dbSNP
rs575428714 2099 dbSNP
rs1243815150 2103 dbSNP
rs1282271456 2104 dbSNP
rs1358196559 2106 dbSNP
rs1199729731 2120 dbSNP
rs1461591516 2128 dbSNP
rs1482784663 2129 dbSNP
rs1203063481 2136 dbSNP
rs966848519 2140 dbSNP
rs1438664158 2141 dbSNP
rs1187096791 2148 dbSNP
rs188704571 2148 dbSNP
rs1367124844 2152 dbSNP
rs1473966102 2154 dbSNP
rs976434801 2157 dbSNP
rs1390054897 2159 dbSNP
rs1427263002 2160 dbSNP
rs1264709636 2166 dbSNP
rs943746895 2168 dbSNP
rs372495162 2179 dbSNP
rs1317469876 2183 dbSNP
rs185507106 2188 dbSNP
rs180983842 2192 dbSNP
rs1331758863 2195 dbSNP
rs1342098461 2196 dbSNP
rs61762280 2205 dbSNP
rs1339297057 2206 dbSNP
rs1296829593 2207 dbSNP
rs1028495240 2213 dbSNP
rs953637297 2214 dbSNP
rs1253208756 2235 dbSNP
rs1340114506 2236 dbSNP
rs550878088 2240 dbSNP
rs998594598 2245 dbSNP
rs1453937552 2250 dbSNP
rs566403211 2258 dbSNP
rs1184520301 2259 dbSNP
rs901211152 2261 dbSNP
rs1408768475 2262 dbSNP
rs1171030318 2263 dbSNP
rs1373190181 2265 dbSNP
rs1465091460 2271 dbSNP
rs1037428592 2272 dbSNP
rs1329684454 2273 dbSNP
rs1004324655 2275 dbSNP
rs1463752858 2284 dbSNP
rs118080805 2291 dbSNP
rs1048940384 2300 dbSNP
rs145050491 2302 dbSNP
rs962488177 2303 dbSNP
rs1296176714 2304 dbSNP
rs930429978 2312 dbSNP
rs142774218 2315 dbSNP
rs1254487508 2320 dbSNP
rs1366704692 2321 dbSNP
rs550823171 2325 dbSNP
rs1182924250 2338 dbSNP
rs532422163 2341 dbSNP
rs1244778229 2346 dbSNP
rs78813594 2350 dbSNP
rs77593303 2351 dbSNP
rs61762281 2352 dbSNP
rs148508496 2356 dbSNP
rs67787583 2356 dbSNP
rs753961418 2356 dbSNP
rs1003623909 2359 dbSNP
rs1470054782 2366 dbSNP
rs200800532 2373 dbSNP
rs565197421 2377 dbSNP
rs1457515952 2382 dbSNP
rs11652581 2388 dbSNP
rs1458573055 2398 dbSNP
rs1289404382 2410 dbSNP
rs1197690663 2418 dbSNP
rs1023625678 2424 dbSNP
rs528491176 2431 dbSNP
rs1054077936 2440 dbSNP
rs1327558376 2441 dbSNP
rs1218342580 2449 dbSNP
rs1261831798 2450 dbSNP
rs1385547933 2455 dbSNP
rs966451492 2456 dbSNP
rs1208570895 2458 dbSNP
rs1270459284 2459 dbSNP
rs1480463494 2463 dbSNP
rs914963569 2464 dbSNP
rs1054079338 2484 dbSNP
rs558638698 2489 dbSNP
rs1409260897 2493 dbSNP
rs1473453154 2495 dbSNP
rs999371762 2498 dbSNP
rs989613817 2502 dbSNP
rs79864792 2509 dbSNP
rs902343775 2516 dbSNP
rs15948 2520 dbSNP
rs943776747 2526 dbSNP
rs1367583203 2530 dbSNP
rs1387955742 2530 dbSNP
rs1162331810 2532 dbSNP
rs61762282 2540 dbSNP
rs146628920 2544 dbSNP
rs879060244 2550 dbSNP
rs189028582 2555 dbSNP
rs1049403107 2560 dbSNP
rs1321462833 2560 dbSNP
rs1243309410 2561 dbSNP
rs1294519706 2572 dbSNP
rs930944310 2577 dbSNP
rs1203728794 2578 dbSNP
rs1233188933 2591 dbSNP
rs920863876 2600 dbSNP
rs974024756 2604 dbSNP
rs563515128 2606 dbSNP
rs545218155 2607 dbSNP
rs1004594476 2615 dbSNP
rs908031603 2622 dbSNP
rs1048469632 2627 dbSNP
rs1425391951 2628 dbSNP
rs982220310 2629 dbSNP
rs970782052 2630 dbSNP
rs1223284571 2634 dbSNP
rs1013004051 2644 dbSNP
rs1444683539 2648 dbSNP
rs1023697714 2651 dbSNP
rs184388452 2662 dbSNP
rs1012259348 2664 dbSNP
rs958241354 2668 dbSNP
rs553639090 2670 dbSNP
rs895014934 2670 dbSNP
rs533507506 2674 dbSNP
rs751041146 2677 dbSNP
rs1228292349 2678 dbSNP
rs1271941792 2680 dbSNP
rs1032302522 2681 dbSNP
rs999841173 2685 dbSNP
rs939306391 2694 dbSNP
rs1351864540 2703 dbSNP
rs1185134026 2706 dbSNP
rs1243693774 2706 dbSNP
rs1281567002 2708 dbSNP
rs1443963342 2709 dbSNP
rs1448854561 2713 dbSNP
rs1186558086 2723 dbSNP
rs1049098 2731 dbSNP
rs1328946192 2737 dbSNP
rs61762283 2739 dbSNP
rs1411680226 2743 dbSNP
rs1171431055 2749 dbSNP
rs1040839405 2750 dbSNP
rs193151207 2755 dbSNP
rs1339172539 2756 dbSNP
rs1383982993 2766 dbSNP
rs1435064604 2770 dbSNP
rs1405025091 2774 dbSNP
rs1296017818 2775 dbSNP
rs1007993550 2777 dbSNP
rs1363483369 2777 dbSNP
rs1367438404 2789 dbSNP
rs1156792511 2794 dbSNP
rs1277487249 2794 dbSNP
rs1399975866 2796 dbSNP
rs1408483776 2800 dbSNP
rs1160039235 2802 dbSNP
rs1477188721 2803 dbSNP
rs536331949 2806 dbSNP
rs1042067810 2813 dbSNP
rs1476433028 2817 dbSNP
rs945007674 2819 dbSNP
rs1490856252 2820 dbSNP
rs1424531390 2822 dbSNP
rs1261046656 2829 dbSNP
rs1178812085 2839 dbSNP
rs1407362719 2840 dbSNP
rs1457000171 2843 dbSNP
rs1316884047 2848 dbSNP
rs568995973 2848 dbSNP
rs1430844980 2849 dbSNP
rs868601759 2849 dbSNP
rs763046117 2852 dbSNP
rs930996930 2856 dbSNP
rs61762284 2857 dbSNP
rs61762285 2858 dbSNP
rs921467722 2858 dbSNP
rs932394313 2858 dbSNP
rs977302363 2858 dbSNP
rs1286276482 2859 dbSNP
rs1220737096 2866 dbSNP
rs1447570250 2866 dbSNP
rs940924637 2867 dbSNP
rs1489874100 2868 dbSNP
rs1217802452 2870 dbSNP
rs908064178 2872 dbSNP
rs1201889036 2879 dbSNP
rs982805936 2883 dbSNP
rs1282229618 2898 dbSNP
rs1472471815 2898 dbSNP
rs952728755 2914 dbSNP
rs1401869409 2920 dbSNP
rs1346858469 2923 dbSNP
rs982293984 2926 dbSNP
rs1026981327 2949 dbSNP
rs1013036022 2951 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545216. RNA binding protein: AGO2. Condition:miR-124 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 1398.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM545216
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-124 transfection
Location of target site ENST00000398970.5 | 3UTR | UGUAUUUUCAUUCCAGGUGAAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000398970.5 | 3UTR | UGUGUAUUUUCAUUCCAGGUGAAAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-216b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071722 CCNK cyclin K 2 2
MIRT074768 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT101407 SSR1 signal sequence receptor subunit 1 2 2
MIRT241289 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 4
MIRT268292 CCND1 cyclin D1 2 8
MIRT445347 IFNA6 interferon alpha 6 2 2
MIRT446663 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT447595 MSH3 mutS homolog 3 2 2
MIRT448485 SEMA4F ssemaphorin 4F 2 2
MIRT450309 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT451850 TXNDC5 thioredoxin domain containing 5 2 2
MIRT483613 SMC5 structural maintenance of chromosomes 5 2 2
MIRT485633 EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2 2
MIRT499766 CIRH1A UTP4, small subunit processome component 2 6
MIRT503337 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT513007 MAN1A2 mannosidase alpha class 1A member 2 2 2
MIRT513529 RHOQ ras homolog family member Q 2 4
MIRT521499 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT524335 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT524731 BRI3BP BRI3 binding protein 2 8
MIRT525326 SNX29 sorting nexin 29 2 2
MIRT526264 CCDC169 coiled-coil domain containing 169 2 2
MIRT527428 NRL neural retina leucine zipper 2 2
MIRT527512 ZNF134 zinc finger protein 134 2 2
MIRT528881 ATF3 activating transcription factor 3 2 2
MIRT529578 IGBP1 immunoglobulin binding protein 1 2 4
MIRT531122 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT531341 TGIF2LX TGFB induced factor homeobox 2 like, X-linked 2 2
MIRT532433 DHX33 DEAH-box helicase 33 2 2
MIRT534032 STX7 syntaxin 7 2 2
MIRT534538 SACS sacsin molecular chaperone 2 4
MIRT538886 BRWD3 bromodomain and WD repeat domain containing 3 2 2
MIRT539628 CD19 CD19 molecule 2 8
MIRT540327 ATAT1 alpha tubulin acetyltransferase 1 2 8
MIRT540353 OCLN occludin 2 6
MIRT540699 ATG10 autophagy related 10 2 4
MIRT541033 STRBP spermatid perinuclear RNA binding protein 2 8
MIRT541945 NBPF10 NBPF member 10 2 4
MIRT543505 PLS1 plastin 1 2 2
MIRT551164 UBTF upstream binding transcription factor, RNA polymerase I 2 4
MIRT551790 ZNF117 zinc finger protein 117 2 4
MIRT553227 TWF1 twinfilin actin binding protein 1 2 2
MIRT559622 AKIRIN2 akirin 2 2 2
MIRT559719 ADORA2B adenosine A2b receptor 2 2
MIRT564600 ZNF781 zinc finger protein 781 2 2
MIRT567015 KLHL15 kelch like family member 15 2 2
MIRT569564 C7orf26 chromosome 7 open reading frame 26 2 2
MIRT572155 DDX3X DEAD-box helicase 3, X-linked 2 2
MIRT575399 Zdhhc22 zinc finger, DHHC-type containing 22 2 5
MIRT607322 PKNOX1 PBX/knotted 1 homeobox 1 2 4
MIRT607953 NFAM1 NFAT activating protein with ITAM motif 1 2 10
MIRT607979 ZDHHC22 zinc finger DHHC-type containing 22 2 7
MIRT609145 ZNF610 zinc finger protein 610 2 4
MIRT609206 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT609338 HRASLS5 HRAS like suppressor family member 5 2 2
MIRT609725 KIF5C kinesin family member 5C 2 4
MIRT610014 MED24 mediator complex subunit 24 2 4
MIRT610407 TMEM245 transmembrane protein 245 2 2
MIRT610559 NBPF14 NBPF member 14 2 2
MIRT611291 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT611399 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT611432 C11orf45 chromosome 11 open reading frame 45 2 4
MIRT611710 SLFN13 schlafen family member 13 2 2
MIRT611721 ANK3 ankyrin 3 2 2
MIRT611830 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 4
MIRT611977 ZNF175 zinc finger protein 175 2 2
MIRT612073 CEP135 centrosomal protein 135 2 4
MIRT612195 CCDC77 coiled-coil domain containing 77 2 2
MIRT612320 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT612354 TNRC6C trinucleotide repeat containing 6C 2 4
MIRT612635 PTEN phosphatase and tensin homolog 2 2
MIRT612773 MLXIP MLX interacting protein 2 4
MIRT612788 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT612853 JAZF1 JAZF zinc finger 1 2 2
MIRT612965 GID4 GID complex subunit 4 homolog 2 6
MIRT613132 DUSP6 dual specificity phosphatase 6 2 2
MIRT613388 AAK1 AP2 associated kinase 1 2 2
MIRT615058 CRY2 cryptochrome circadian clock 2 2 4
MIRT616046 HSPA12B heat shock protein family A (Hsp70) member 12B 2 2
MIRT617962 SEPT9 septin 9 2 2
MIRT618413 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT622448 RNF213 ring finger protein 213 2 2
MIRT623611 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT625709 SHROOM1 shroom family member 1 2 2
MIRT630646 ELK1 ELK1, ETS transcription factor 2 2
MIRT630970 KIAA2022 neurite extension and migration factor 2 2
MIRT631003 SPAG7 sperm associated antigen 7 2 2
MIRT640385 EMC1 ER membrane protein complex subunit 1 2 4
MIRT641064 WBSCR17 polypeptide N-acetylgalactosaminyltransferase 17 2 2
MIRT641780 ZDHHC7 zinc finger DHHC-type containing 7 2 4
MIRT646310 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT646624 CENPL centromere protein L 2 2
MIRT659653 CDH2 cadherin 2 2 2
MIRT666161 SP1 Sp1 transcription factor 2 2
MIRT667638 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT668988 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT680949 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT695238 PBK PDZ binding kinase 2 2
MIRT700036 RPL22 ribosomal protein L22 2 2
MIRT707685 GPR50 G protein-coupled receptor 50 2 2
MIRT709324 HMBOX1 homeobox containing 1 2 2
MIRT710176 MTRF1L mitochondrial translational release factor 1 like 2 2
MIRT712007 F9 coagulation factor IX 2 2
MIRT714219 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT714496 HSPA4 heat shock protein family A (Hsp70) member 4 2 2
MIRT714575 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT715982 TFRC transferrin receptor 2 2
MIRT717870 TRAPPC3L trafficking protein particle complex 3 like 2 2
MIRT718289 MINA ribosomal oxygenase 2 2 2
MIRT725200 PTRF caveolae associated protein 1 2 2
MIRT737338 TPX2 TPX2, microtubule nucleation factor 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-216b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-216b 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) NULL 15625 Microarray embryos 22921993 2012 up-regulated
miR-216b Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Quantitative real-time PCR human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Curcumin NULL 969516 Quantitative real-time PCR Y79 RB cells. 22510010 2012 down-regulated
miR-216b Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-216b Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-216b Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-216b-3p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-216b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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