miRTarBase - #MIRT524461


—
pre-miRNA Information
pre-miRNA hsa-mir-4703   
Genomic Coordinates chr13: 51552589 - 51552667
Description Homo sapiens miR-4703 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4703-3p
Sequence 49| UGUAGUUGUAUUGUAUUGCCAC |70
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1460841833 5 dbSNP
rs775733304 5 dbSNP
rs756076492 10 dbSNP
rs1378936855 11 dbSNP
rs1049480258 12 dbSNP
rs555347919 13 dbSNP
rs1343138432 18 dbSNP
rs1011011214 19 dbSNP
rs1008216326 21 dbSNP
rs1238676458 22 dbSNP
Putative Targets

Gene Information
Gene Symbol CMPK1   
Synonyms CK, CMK, CMPK, UMK, UMP-CMPK, UMPK
Description cytidine/uridine monophosphate kinase 1
Transcript NM_001136140   
Other Transcripts NM_016308   
Expression
Putative miRNA Targets on CMPK1
3'UTR of CMPK1
(miRNA target sites are highlighted)		 
>CMPK1|NM_001136140|3'UTR
   1 TTCTAAACCTGAAGGCATCCTTGAAATCATGCTTGAATATTGCTTTGATAGCTGCTATCATGACCCCTTTTTAAGGCAAT
  81 TCTAATCTTTCATAACTACATCTCAATTAGTGGCTGGAAAGTACATGGTAAAACAAAGTAAATTTTTTTATGTTCTTTTT
 161 TTTGGTCACAGGAGTAGACAGTGAATTCAGGTTTAACTTCACCTTAGTTATGGTGCTCACCAAACGAAGGGTATCAGCTA
 241 TTTTTTTTAAAATTCAAAAAGAATATCCCTTTTATAGTTTGTGCCTTCTGTGAGCAAAACTTTTTAGTACGCGTATATAT
 321 CCCTCTAGTAATCACAACATTTTAGGATTTAGGGATACCCGCTTCCTCTTTTTCTTGCAAGTTTTAAATTTCCAACCTTA
 401 AGTGAATTTGTGGACCAAATTTCAAAGGAACTTTTTGTGTAGTCAGTTCTTGCACAATGTGTTTGGTAAACAAACTCAAA
 481 ATGGATTCTTAGGAGCATTTTAGTGTTTATTAAATAACTGACCATTTGCTGTAGAAAGATGAGAAAACTTAAGCTTTGTT
 561 TTACTACAACTTGTACAAAGTTGTATGACAGGGCATATTCTTTGCTTCCAAGATTTGGGTTGGGGGCACTAGGGGTTCAG
 641 AGCCTGGCAGAATTGTCAGCTTTAGTCTGACATAATCTAAGGGTATGGGGCAAGGATCACATCTAATGCTTGTGTTCCTT
 721 ATACTCTATTATATAGTGTTATTCATGATTCAGCTGATCTTAACAAAATTCGTAGCAGTGGAACCTTGAAATGCATGTGG
 801 CTAGATTTATGCTAAAATGATTCTCAGTTAGCATTTTAGTAACACTTCAAAGGTTTTTTTTTGTTTGTTTTCTAGACTTA
 881 ATAAAAGCTTAGGATTAATTAGAAGAAGCAATCTAGTTAAATTTCCCATTTGTATTTTATTTTCTTGAATACTTTTTTCA
 961 TAGTTATTTGTTTAAAAAGATTTAAAAATCATTGCACTTTGGTCAGAAAAATAATAAATATATCTTATAAATGTTTGATT
1041 CCCTTCCTTGCTATTTTTATTCAGTAGATTTTTGTTTGGCATCATGTTGAAGCACCGAAAGATAAATGATTTTTAAAAGG
1121 CTATAGAGTCCAAAGGAATATTCTTTTACACCAATTCTTCCTTTAAAAATCTCTGAGGAATTTGTTTTCGCCTTACTTTT
1201 TTTTCTTCTGTCACAATGCTAAGTGGTATCCGAGGTTCTTAATATGAGATTTAAAATCTTAAAATGTTTCTTATTTTCAG
1281 CACTTACATCATTTGGTACACAGGGTCAAATAGGGCAAATAATTTTGTCTTTGTATAATAGATTTGATATTTAAAGTCAC
1361 TGGAAATAGGACAAGTTAATGGATGTTTTTATATTTTAATAGAATCATTTATTTCTATGTGTTATGAAATTCACTTAATG
1441 ATAAATTTTTCAACATACTTGCCATTAGAAAACAAAGTATTGCTAAGTACTATAACATATTGGCCACTAAAATTCATATT
1521 GAGATTATCTTGGTTTCTTGGAAGAGATAGGAATGAGTTCTTATCTAGTGTTGCAGGCCAGCAAATACAGAGGTGGTTTA
1601 ATCAAACAGCTCTAGTATGAAGCAAGAGTAAAGACTAAGGTTTCGAGAGCATTCCTACTCACATAAGTGAAGAAATCTGT
1681 CAGATAGGAATCTAAATATTTATAGTGAGATTGTGAAAGCAACCTTAAAGTTTTGAAGAAGACTGATGAGACTAGGTGCT
1761 TTGCTTCCTTTCATCAGGTATCTTTCTGTGGCATTTGAGAACAGAAACCAAGAAACATGGTAATTACTAAATTATGAGGC
1841 TTTGCTTTTTGTTTGCTTTTAAGTAGAAAAACATGTTGGCAACATTGAGTTTTGGAGTTGATTGAGATAATATGACTTAA
1921 CTAGTTTTGTCATTCCATTTGTTAAAGATACAGTCACCAAGAATGTTTTGAGTTTTTTGAAAGACCCCAATTTAAGCCTT
2001 GCTTATTTTTAAATTATTTCCATTCAGTGATGTTGGATGTATATCAGTTATTTAGTAAATAATCTCAATAAATTTTGTGC
2081 TGTGGCCTTTGCTAAAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' caCCGUUAUG-UUA-----UGUUGAUGu 5'
            |||||| | |||     |:|||||| 
Target 5' aaGGCAATTCTAATCTTTCATAACTACa 3'
 73 - 100 152.00 -15.50
2 
miRNA  3' caCCGUUAUGUUAUGUUGAUgu 5'
            | :||||::|  :|||||  
Target 5' gaGATAATATGACTTAACTAgt 3'
 1904 - 1925 128.00 -5.80
3 
miRNA  3' caccGUUAUGU-UA-UGUUGAUGu 5'
              ||| | | || ::||:||| 
Target 5' aaacCAAGAAACATGGTAATTACt 3'
 1805 - 1828 122.00 -5.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30123969 16 COSMIC
COSN31572823 45 COSMIC
COSN30178130 98 COSMIC
COSN30155879 105 COSMIC
COSN30166247 140 COSMIC
COSN31598991 141 COSMIC
COSN31570859 146 COSMIC
COSN30643319 150 COSMIC
COSN31581859 150 COSMIC
COSN29267317 156 COSMIC
COSN30127041 226 COSMIC
COSN31534627 227 COSMIC
COSN31534259 249 COSMIC
COSN31568855 251 COSMIC
COSN26548569 299 COSMIC
COSN24296915 338 COSMIC
COSN24296925 863 COSMIC
COSN31483235 863 COSMIC
COSN31596754 1004 COSMIC
COSN31577080 1039 COSMIC
COSN29468430 1087 COSMIC
COSN32056902 1143 COSMIC
COSN29707418 1205 COSMIC
COSN1446999 1319 COSMIC
COSN24294616 1650 COSMIC
COSN17794164 2004 COSMIC
COSN19090186 2046 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs3125648 15 dbSNP
rs867076992 16 dbSNP
rs1246062425 19 dbSNP
rs771523327 30 dbSNP
rs185243869 31 dbSNP
rs956424126 33 dbSNP
rs746725181 35 dbSNP
rs1421895087 41 dbSNP
rs770588462 42 dbSNP
rs1365801525 44 dbSNP
rs1334784300 48 dbSNP
rs1457794181 50 dbSNP
rs954262438 60 dbSNP
rs1292546352 63 dbSNP
rs1010365974 66 dbSNP
rs531332693 78 dbSNP
rs1390893055 80 dbSNP
rs543090281 85 dbSNP
rs1019903392 100 dbSNP
rs1276306505 101 dbSNP
rs191223317 113 dbSNP
rs781259877 114 dbSNP
rs1460930422 117 dbSNP
rs1373630579 119 dbSNP
rs1279804599 121 dbSNP
rs1309519228 126 dbSNP
rs927302631 127 dbSNP
rs1265068954 128 dbSNP
rs1159798060 135 dbSNP
rs952049969 139 dbSNP
rs913620566 141 dbSNP
rs529020626 142 dbSNP
rs907913601 152 dbSNP
rs1248040306 156 dbSNP
rs979061458 156 dbSNP
rs547975641 162 dbSNP
rs1488219533 169 dbSNP
rs1269381635 170 dbSNP
rs1211098038 184 dbSNP
rs566287088 191 dbSNP
rs922435459 192 dbSNP
rs113534701 203 dbSNP
rs1049617445 208 dbSNP
rs1422409894 213 dbSNP
rs762721411 221 dbSNP
rs1273231470 225 dbSNP
rs1440339637 226 dbSNP
rs1321185639 236 dbSNP
rs1163710076 241 dbSNP
rs1036886114 249 dbSNP
rs112300032 249 dbSNP
rs2820981 250 dbSNP
rs995557751 251 dbSNP
rs1026904973 276 dbSNP
rs200994093 277 dbSNP
rs117696989 279 dbSNP
rs1054618202 282 dbSNP
rs891511120 291 dbSNP
rs1485190891 301 dbSNP
rs761320410 307 dbSNP
rs575938684 311 dbSNP
rs907351591 312 dbSNP
rs11554567 313 dbSNP
rs537439324 314 dbSNP
rs1366153543 322 dbSNP
rs867680617 323 dbSNP
rs1020476544 334 dbSNP
rs761057260 338 dbSNP
rs1044457 361 dbSNP
rs1322493937 362 dbSNP
rs1288215490 367 dbSNP
rs1466408898 379 dbSNP
rs984773870 394 dbSNP
rs182966385 397 dbSNP
rs1171403647 410 dbSNP
rs925059187 419 dbSNP
rs1015330496 422 dbSNP
rs962190808 423 dbSNP
rs1426152682 424 dbSNP
rs1261719701 432 dbSNP
rs534804633 447 dbSNP
rs990527117 453 dbSNP
rs530211460 456 dbSNP
rs976117420 458 dbSNP
rs553507540 460 dbSNP
rs571912569 462 dbSNP
rs1210552889 470 dbSNP
rs1343161935 484 dbSNP
rs922466390 503 dbSNP
rs879678130 505 dbSNP
rs1276959178 510 dbSNP
rs917803147 519 dbSNP
rs1306981903 531 dbSNP
rs933799044 532 dbSNP
rs985365173 533 dbSNP
rs1294827665 536 dbSNP
rs539301652 544 dbSNP
rs1396500790 545 dbSNP
rs949345313 547 dbSNP
rs1310867005 557 dbSNP
rs1181573079 558 dbSNP
rs868763332 559 dbSNP
rs935675075 574 dbSNP
rs1413877417 576 dbSNP
rs1370790095 578 dbSNP
rs188113417 579 dbSNP
rs891454394 581 dbSNP
rs1460071244 591 dbSNP
rs896997573 596 dbSNP
rs1164818461 612 dbSNP
rs931185079 621 dbSNP
rs771751143 624 dbSNP
rs889894209 625 dbSNP
rs1483585835 626 dbSNP
rs1358913235 631 dbSNP
rs1007281336 632 dbSNP
rs546733194 634 dbSNP
rs1266138700 635 dbSNP
rs1247016889 647 dbSNP
rs1336876017 654 dbSNP
rs907387568 658 dbSNP
rs1232524738 659 dbSNP
rs1350869884 660 dbSNP
rs1309516482 665 dbSNP
rs114542090 666 dbSNP
rs1020424309 674 dbSNP
rs1293621031 678 dbSNP
rs1458937824 683 dbSNP
rs775028074 692 dbSNP
rs1419752663 696 dbSNP
rs754153282 699 dbSNP
rs1035021860 704 dbSNP
rs888068728 705 dbSNP
rs1462856216 708 dbSNP
rs1006880353 710 dbSNP
rs1473152996 713 dbSNP
rs755207436 715 dbSNP
rs1180053978 718 dbSNP
rs1418740712 721 dbSNP
rs1268246439 728 dbSNP
rs1211719048 729 dbSNP
rs779043267 734 dbSNP
rs1000394987 756 dbSNP
rs1447028457 758 dbSNP
rs1303159942 761 dbSNP
rs1212958238 769 dbSNP
rs543379745 772 dbSNP
rs976148582 773 dbSNP
rs1334812411 775 dbSNP
rs1030352002 776 dbSNP
rs955213110 777 dbSNP
rs1380206639 789 dbSNP
rs1454817687 790 dbSNP
rs985227894 796 dbSNP
rs1458256069 800 dbSNP
rs1391403436 809 dbSNP
rs1157201071 824 dbSNP
rs971013830 826 dbSNP
rs752915746 827 dbSNP
rs972623021 838 dbSNP
rs935972744 840 dbSNP
rs1376325197 849 dbSNP
rs918536577 852 dbSNP
rs1286180760 854 dbSNP
rs911280051 854 dbSNP
rs931133236 854 dbSNP
rs561684776 855 dbSNP
rs1256279582 860 dbSNP
rs1240962321 864 dbSNP
rs1286963080 868 dbSNP
rs1041409964 880 dbSNP
rs901175157 899 dbSNP
rs1302087804 901 dbSNP
rs1435113107 909 dbSNP
rs912927222 910 dbSNP
rs1010689148 915 dbSNP
rs1382070179 920 dbSNP
rs945669980 924 dbSNP
rs1045509289 927 dbSNP
rs10198 937 dbSNP
rs906917811 946 dbSNP
rs937065661 951 dbSNP
rs1394644268 954 dbSNP
rs1439774120 956 dbSNP
rs1178369874 961 dbSNP
rs191207375 962 dbSNP
rs541131173 964 dbSNP
rs1243837583 968 dbSNP
rs559539654 981 dbSNP
rs1034532447 991 dbSNP
rs1446256659 992 dbSNP
rs959350762 998 dbSNP
rs1212690661 1006 dbSNP
rs1345305147 1011 dbSNP
rs370728568 1021 dbSNP
rs1012002699 1022 dbSNP
rs1463853315 1044 dbSNP
rs1329640306 1047 dbSNP
rs551724003 1052 dbSNP
rs1268980749 1058 dbSNP
rs1025185315 1064 dbSNP
rs1006500817 1079 dbSNP
rs970410245 1085 dbSNP
rs1447628891 1094 dbSNP
rs1315200362 1097 dbSNP
rs972399563 1098 dbSNP
rs1281305397 1104 dbSNP
rs760271138 1106 dbSNP
rs78590846 1107 dbSNP
rs1302564271 1115 dbSNP
rs1417429736 1117 dbSNP
rs1167369750 1125 dbSNP
rs1326171802 1137 dbSNP
rs1197067550 1144 dbSNP
rs1475054768 1153 dbSNP
rs1257043938 1160 dbSNP
rs1368922398 1175 dbSNP
rs997434602 1176 dbSNP
rs1030383314 1178 dbSNP
rs745854327 1182 dbSNP
rs1205398095 1187 dbSNP
rs911065217 1190 dbSNP
rs1270303320 1191 dbSNP
rs1213418995 1197 dbSNP
rs1357677993 1197 dbSNP
rs1244515828 1206 dbSNP
rs1477395465 1209 dbSNP
rs1191756213 1211 dbSNP
rs1431344315 1213 dbSNP
rs1476721979 1214 dbSNP
rs953499994 1218 dbSNP
rs1355204764 1219 dbSNP
rs145943145 1226 dbSNP
rs780012973 1232 dbSNP
rs1352926532 1236 dbSNP
rs1328284135 1237 dbSNP
rs1331102404 1239 dbSNP
rs1348263898 1247 dbSNP
rs1395209785 1253 dbSNP
rs1166992021 1272 dbSNP
rs1435833631 1289 dbSNP
rs1474131088 1291 dbSNP
rs1294700718 1300 dbSNP
rs1182580218 1301 dbSNP
rs922708813 1305 dbSNP
rs1230754565 1306 dbSNP
rs182786283 1308 dbSNP
rs17103161 1312 dbSNP
rs1275658415 1313 dbSNP
rs749029954 1316 dbSNP
rs1212336739 1323 dbSNP
rs904747348 1328 dbSNP
rs552073989 1335 dbSNP
rs990097428 1336 dbSNP
rs1000460217 1350 dbSNP
rs1371458983 1351 dbSNP
rs913100368 1380 dbSNP
rs1279180134 1388 dbSNP
rs1216011147 1407 dbSNP
rs1437349280 1407 dbSNP
rs967042517 1413 dbSNP
rs1287285583 1418 dbSNP
rs1327891432 1432 dbSNP
rs1055935390 1433 dbSNP
rs1221579632 1435 dbSNP
rs1270980991 1439 dbSNP
rs981138365 1444 dbSNP
rs1405415236 1446 dbSNP
rs1487240575 1447 dbSNP
rs894642888 1448 dbSNP
rs116147582 1453 dbSNP
rs1024711953 1455 dbSNP
rs1191158399 1456 dbSNP
rs138974275 1465 dbSNP
rs1424127618 1469 dbSNP
rs1269241960 1472 dbSNP
rs1369861055 1473 dbSNP
rs1218462280 1474 dbSNP
rs993768353 1476 dbSNP
rs1283883725 1478 dbSNP
rs1220001731 1483 dbSNP
rs1350272949 1484 dbSNP
rs937095087 1488 dbSNP
rs1055935763 1491 dbSNP
rs1476260254 1492 dbSNP
rs1301365989 1493 dbSNP
rs1169929521 1494 dbSNP
rs1440177832 1495 dbSNP
rs571446549 1496 dbSNP
rs1370241740 1497 dbSNP
rs539602870 1509 dbSNP
rs111466903 1518 dbSNP
rs1303782131 1520 dbSNP
rs984005374 1524 dbSNP
rs1158055739 1531 dbSNP
rs576253238 1533 dbSNP
rs1396454240 1549 dbSNP
rs1368033608 1550 dbSNP
rs942167909 1554 dbSNP
rs879484786 1565 dbSNP
rs1188777106 1566 dbSNP
rs922687329 1591 dbSNP
rs1036621116 1594 dbSNP
rs3088062 1601 dbSNP
rs1211982936 1605 dbSNP
rs1486780010 1609 dbSNP
rs997718623 1617 dbSNP
rs925948936 1623 dbSNP
rs1342936528 1633 dbSNP
rs555355359 1645 dbSNP
rs573678683 1646 dbSNP
rs1359723004 1651 dbSNP
rs1288091258 1653 dbSNP
rs1282070491 1667 dbSNP
rs1415096131 1674 dbSNP
rs774212843 1676 dbSNP
rs1056045222 1712 dbSNP
rs1433611827 1721 dbSNP
rs747741314 1723 dbSNP
rs1373119682 1725 dbSNP
rs1171851736 1732 dbSNP
rs569073503 1735 dbSNP
rs1419354512 1741 dbSNP
rs1189175653 1749 dbSNP
rs1293273133 1754 dbSNP
rs1007673597 1757 dbSNP
rs1350823887 1758 dbSNP
rs1210403947 1765 dbSNP
rs1215873063 1768 dbSNP
rs771654473 1778 dbSNP
rs1481061147 1781 dbSNP
rs1046337188 1785 dbSNP
rs1202461161 1789 dbSNP
rs1032813269 1798 dbSNP
rs1294762411 1803 dbSNP
rs957230014 1809 dbSNP
rs1233730870 1810 dbSNP
rs772558703 1821 dbSNP
rs541071605 1827 dbSNP
rs1025223723 1842 dbSNP
rs967327141 1850 dbSNP
rs1299398094 1857 dbSNP
rs1459965581 1866 dbSNP
rs888109388 1872 dbSNP
rs981336486 1881 dbSNP
rs1448590614 1882 dbSNP
rs761267385 1886 dbSNP
rs1416188703 1890 dbSNP
rs1187623165 1893 dbSNP
rs537680955 1898 dbSNP
rs1252849573 1905 dbSNP
rs1472567290 1910 dbSNP
rs1005208080 1912 dbSNP
rs1164413745 1923 dbSNP
rs1257396397 1948 dbSNP
rs139870385 1950 dbSNP
rs187432473 1952 dbSNP
rs577695495 1957 dbSNP
rs1029918721 1964 dbSNP
rs991270625 1984 dbSNP
rs1386224555 1985 dbSNP
rs1402821724 1987 dbSNP
rs1332554727 1990 dbSNP
rs1335984847 1991 dbSNP
rs1389227456 2003 dbSNP
rs1371945901 2011 dbSNP
rs1325947813 2013 dbSNP
rs750978109 2023 dbSNP
rs3835608 2028 dbSNP
rs908917597 2032 dbSNP
rs1164669253 2033 dbSNP
rs1454630292 2046 dbSNP
rs6795 2048 dbSNP
rs1316695822 2057 dbSNP
rs1418617178 2061 dbSNP
rs563743539 2069 dbSNP
rs1195525625 2071 dbSNP
rs1238788243 2080 dbSNP
rs1036974925 2088 dbSNP
rs1250988559 2093 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 51727.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM1065667. RNA binding protein: AGO1. Condition:4-thiouridine ...

- Memczak S; Jens M; Elefsinioti A; Torti F; et al., 2013, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' caccGUUAUG-UUA-----UGUUGAUGu 5'
              |||| | |||     |:|||||| 
Target 5' ----CAAUUCUAAUCUUUCAUAACUACa 3'
 		1 - 24
Article - Memczak S; Jens M; Elefsinioti A; Torti F; et al.
- Nature, 2013
Circular RNAs (circRNAs) in animals are an enigmatic class of RNA with unknown function. To explore circRNAs systematically, we sequenced and computationally analysed human, mouse and nematode RNA. We detected thousands of well-expressed, stable circRNAs, often showing tissue/developmental-stage-specific expression. Sequence analysis indicated important regulatory functions for circRNAs. We found that a human circRNA, antisense to the cerebellar degeneration-related protein 1 transcript (CDR1as), is densely bound by microRNA (miRNA) effector complexes and harbours 63 conserved binding sites for the ancient miRNA miR-7. Further analyses indicated that CDR1as functions to bind miR-7 in neuronal tissues. Human CDR1as expression in zebrafish impaired midbrain development, similar to knocking down miR-7, suggesting that CDR1as is a miRNA antagonist with a miRNA-binding capacity ten times higher than any other known transcript. Together, our data provide evidence that circRNAs form a large class of post-transcriptional regulators. Numerous circRNAs form by head-to-tail splicing of exons, suggesting previously unrecognized regulatory potential of coding sequences.
LinkOut: [PMID: 23446348]
CLIP-seq Support 1 for dataset GSM1065667
Method / RBP PAR-CLIP / AGO1
Cell line / Condition HEK293 / 4-thiouridine, ML_MM_6
Location of target site ENST00000371873.5 | 3UTR | CAAUUCUAAUCUUUCAUAACUACAUCUCAAUUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23446348 / GSE43573
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
42 hsa-miR-4703-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT072026 SCP2 sterol carrier protein 2 2 2
MIRT079071 BIRC5 baculoviral IAP repeat containing 5 2 6
MIRT106648 PLEKHF2 pleckstrin homology and FYVE domain containing 2 2 4
MIRT178174 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2 2
MIRT190328 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 2
MIRT230081 SH3BGRL SH3 domain binding glutamate rich protein like 2 2
MIRT238900 PEX3 peroxisomal biogenesis factor 3 2 2
MIRT473705 MAPK1 mitogen-activated protein kinase 1 2 6
MIRT481891 ANKRD46 ankyrin repeat domain 46 2 4
MIRT483743 ALDH9A1 aldehyde dehydrogenase 9 family member A1 2 2
MIRT488823 MRRF mitochondrial ribosome recycling factor 2 2
MIRT488990 SLC28A1 solute carrier family 28 member 1 2 2
MIRT504173 FAM127B retrotransposon Gag like 8A 2 2
MIRT524461 CMPK1 cytidine/uridine monophosphate kinase 1 2 2
MIRT529787 AP4S1 adaptor related protein complex 4 sigma 1 subunit 2 2
MIRT546449 SLC9A7 solute carrier family 9 member A7 2 2
MIRT547827 IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 2 4
MIRT561462 TCERG1 transcription elongation regulator 1 2 2
MIRT562315 G3BP1 G3BP stress granule assembly factor 1 2 2
MIRT563644 ZNF675 zinc finger protein 675 2 2
MIRT563741 ZNF107 zinc finger protein 107 2 4
MIRT568318 BACH1 BTB domain and CNC homolog 1 2 2
MIRT571528 ZNF367 zinc finger protein 367 2 2
MIRT574840 CADM1 cell adhesion molecule 1 2 2
MIRT612262 MNT MAX network transcriptional repressor 2 4
MIRT622234 SLC25A45 solute carrier family 25 member 45 2 2
MIRT625372 IRGQ immunity related GTPase Q 2 2
MIRT628260 EFCAB14 EF-hand calcium binding domain 14 2 2
MIRT631738 NKX2-1 NK2 homeobox 1 2 2
MIRT646103 GORAB golgin, RAB6 interacting 2 2
MIRT647768 AMOTL1 angiomotin like 1 2 2
MIRT654309 RBMS3 RNA binding motif single stranded interacting protein 3 2 2
MIRT654988 PLCG2 phospholipase C gamma 2 2 2
MIRT659715 CCDC93 coiled-coil domain containing 93 2 2
MIRT666976 PHAX phosphorylated adaptor for RNA export 2 2
MIRT683247 WFDC6 WAP four-disulfide core domain 6 2 2
MIRT688424 DNAL1 dynein axonemal light chain 1 2 2
MIRT691896 FBXL18 F-box and leucine rich repeat protein 18 2 2
MIRT701616 MYO1B myosin IB 2 2
MIRT702141 MAP3K1 mitogen-activated protein kinase kinase kinase 1 2 2
MIRT704403 CTPS1 CTP synthase 1 2 2
MIRT719515 RAB10 RAB10, member RAS oncogene family 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4703 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-4703-3p Tamoxifen 2733525 NSC180973 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4703-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4703-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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