pre-miRNA Information
pre-miRNA hsa-mir-4477a   
Genomic Coordinates chr9: 41233755 - 41233835
Description Homo sapiens miR-4477a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4477a
Sequence 48| CUAUUAAGGACAUUUGUGAUUC |69
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1281813060 1 dbSNP
rs1352899679 1 dbSNP
rs1283566158 2 dbSNP
rs1236244724 4 dbSNP
rs75019967 4 dbSNP
rs1348124293 5 dbSNP
rs34026740 8 dbSNP
rs1288237115 9 dbSNP
rs71262206 10 dbSNP
rs1355759977 11 dbSNP
rs1300249508 16 dbSNP
rs1328879592 18 dbSNP
rs139133717 20 dbSNP
Putative Targets

Gene Information
Gene Symbol UGT2A1   
Synonyms UDPGT2A1
Description UDP glucuronosyltransferase family 2 member A1 complex locus
Transcript NM_006798   
Expression
Putative miRNA Targets on UGT2A1
3'UTR of UGT2A1
(miRNA target sites are highlighted)
>UGT2A1|NM_006798|3'UTR
   1 GTCAAGAAAAAGAGGAAATATATATATTTTTAAGTTTGGCAAAATCCTGAGTAGTGTAGTCCTATTAATTCCAGACAAAA
  81 GGAGTTTAACAAAAACACGTCTCCCATCCTGTTTCCAAATTTTCTATTTCTCTACCTGCGATAAGCCTACTGATAAAGCC
 161 TAGATTTTGGCATGATTATTATTAACTTGTGAGTTATAGTCTTCTATTTTTCCTTTGTCTCTCCCTGCTGACTATACCCT
 241 CTTCCTGTCACTTTTCTGACACAAGGATACTACCTAATTTTAAATATGTTCTATTCATAGTATCAAATTATTTTATCGTT
 321 AACCTTAATTAATGATTAACAATATGCTGAATCCTGGTAATGCATACAGTGTAGATGGAATTTGATAGGTGTAAGGAAGA
 401 GTCAAATTCACAAATTTCCATATACCAAACAAATCAGGGAGCCACCGTAGGAGAGTAGTGTGTTATGAGAAAGGTAATGA
 481 TTTCCTTTTTTAATAAAAACAAACTCTTCTGCTTGCTCAATGTTTCAGGAGTTAGAGAATGAATTTTAAGTGTGACGTGC
 561 GTCCCTATTAAATGTCTACAAAATTTTCATTAAGCATATCTAGAAAATCACGGCATAACTTGCCTGCCTTTCTTCAACAT
 641 ATATTCTTATATAACCTGTAGTGGAAGATTTGGGTACTGTCTTTAATAAATCAATCAATCGACTCTTTTATTTCAAGGAG
 721 AAAGTTCTATGTTATATGTTGAAGGTGAACAGATCATATTTAGAGGATATAACAATTAGAAATCTAGAAAATAATTATCA
 801 TTTTTATAAAATTTTTAGTCAACTGTACAAATAATTACATAAAACATCAATTAATTATGCTTAAAAATCACTAATGTTCA
 881 TAATATATAATCACTATTTGTAATCAAAAGTTTAATTTTATGCCAAAAAATAAAAAATGCTTACTTGGAATTTGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' cuUAGUGUUUACAGGAAUUAUc 5'
            ||||| |||||:| ||||| 
Target 5' aaATCACTAATGTTCATAATAt 3'
865 - 886 156.00 -14.10
2
miRNA  3' cuuaguguUUACAGGAAUUAUc 5'
                  | ||||:|||||| 
Target 5' atttgggtACTGTCTTTAATAa 3'
668 - 689 146.00 -8.60
3
miRNA  3' cuUAGUGUUUACAGGAAUUAuc 5'
            |||:: ||   |||||||  
Target 5' ttATCGTTAA---CCTTAATta 3'
313 - 331 137.00 -6.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30465160 9 COSMIC
COSN31548190 9 COSMIC
COSN19706689 14 COSMIC
COSN14121364 15 COSMIC
COSN31509187 20 COSMIC
COSN30124727 21 COSMIC
COSN31573069 27 COSMIC
COSN30122111 45 COSMIC
COSN9051499 58 COSMIC
COSN31525763 81 COSMIC
COSN5865673 92 COSMIC
COSN31598591 139 COSMIC
COSN32064165 158 COSMIC
COSN20075117 160 COSMIC
COSN9051498 522 COSMIC
COSN27711311 556 COSMIC
COSN4838743 611 COSMIC
COSN27916137 791 COSMIC
COSN4838742 864 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1411320571 1 dbSNP
rs1224675475 9 dbSNP
rs767385475 12 dbSNP
rs761881572 15 dbSNP
rs976471834 17 dbSNP
rs751377081 20 dbSNP
rs1275259805 21 dbSNP
rs764039351 24 dbSNP
rs994624184 27 dbSNP
rs1483744914 28 dbSNP
rs961495032 28 dbSNP
rs150470223 32 dbSNP
rs1207373012 39 dbSNP
rs1329123855 43 dbSNP
rs1017633360 73 dbSNP
rs1191990870 77 dbSNP
rs1371756432 81 dbSNP
rs539436729 82 dbSNP
rs187159615 92 dbSNP
rs4148311 99 dbSNP
rs536799448 100 dbSNP
rs552469106 101 dbSNP
rs796134063 102 dbSNP
rs1024602196 103 dbSNP
rs1275886988 105 dbSNP
rs1324537401 109 dbSNP
rs1013250534 114 dbSNP
rs945091240 126 dbSNP
rs1222363727 130 dbSNP
rs776929809 134 dbSNP
rs1053563082 138 dbSNP
rs547983026 139 dbSNP
rs866694061 140 dbSNP
rs1357992023 150 dbSNP
rs1294617098 154 dbSNP
rs1259224393 160 dbSNP
rs926315194 162 dbSNP
rs981985016 164 dbSNP
rs1245564941 170 dbSNP
rs1443359163 171 dbSNP
rs368030038 174 dbSNP
rs1385991559 175 dbSNP
rs919055197 176 dbSNP
rs771317023 178 dbSNP
rs559611402 181 dbSNP
rs1393417153 193 dbSNP
rs1387434901 200 dbSNP
rs1049355613 207 dbSNP
rs1352064254 214 dbSNP
rs929179141 218 dbSNP
rs1308460505 219 dbSNP
rs919163323 230 dbSNP
rs1016963439 232 dbSNP
rs552222344 237 dbSNP
rs976003338 241 dbSNP
rs182465488 247 dbSNP
rs566089567 250 dbSNP
rs1028284292 255 dbSNP
rs1208920477 256 dbSNP
rs35000204 267 dbSNP
rs1188705033 285 dbSNP
rs1362766828 287 dbSNP
rs151238794 289 dbSNP
rs1460241646 302 dbSNP
rs901440016 306 dbSNP
rs957440720 307 dbSNP
rs1418947879 311 dbSNP
rs1252966432 316 dbSNP
rs189817236 317 dbSNP
rs1033123841 318 dbSNP
rs1175951884 324 dbSNP
rs1405160032 328 dbSNP
rs1468036964 329 dbSNP
rs1338376900 331 dbSNP
rs114269062 332 dbSNP
rs1489971469 334 dbSNP
rs778394813 335 dbSNP
rs541633653 342 dbSNP
rs866753934 353 dbSNP
rs1336985530 354 dbSNP
rs187751756 356 dbSNP
rs1241425634 357 dbSNP
rs1330031732 360 dbSNP
rs1014476575 362 dbSNP
rs115247793 366 dbSNP
rs538994259 376 dbSNP
rs1480609111 378 dbSNP
rs1001898556 380 dbSNP
rs1252808969 386 dbSNP
rs887504780 392 dbSNP
rs1325425679 395 dbSNP
rs1387345735 396 dbSNP
rs1383582346 400 dbSNP
rs1199049729 403 dbSNP
rs754567753 407 dbSNP
rs1481510861 408 dbSNP
rs1458382070 409 dbSNP
rs1177996843 425 dbSNP
rs949302072 433 dbSNP
rs538092725 435 dbSNP
rs146405932 437 dbSNP
rs972422746 442 dbSNP
rs556581310 447 dbSNP
rs536699946 450 dbSNP
rs897621992 455 dbSNP
rs1343279831 457 dbSNP
rs1040183727 462 dbSNP
rs1200196024 467 dbSNP
rs866277428 469 dbSNP
rs984132821 483 dbSNP
rs1446982057 504 dbSNP
rs954138356 506 dbSNP
rs944600445 528 dbSNP
rs575789943 534 dbSNP
rs976798299 537 dbSNP
rs910499237 541 dbSNP
rs1050369386 549 dbSNP
rs1191962827 552 dbSNP
rs936057890 556 dbSNP
rs926025464 557 dbSNP
rs567835738 558 dbSNP
rs977499148 560 dbSNP
rs142355774 561 dbSNP
rs1276443552 566 dbSNP
rs534800694 567 dbSNP
rs1001923411 572 dbSNP
rs917402051 574 dbSNP
rs1293736766 581 dbSNP
rs1361776280 582 dbSNP
rs868827887 588 dbSNP
rs559144853 589 dbSNP
rs530745643 590 dbSNP
rs1298114477 596 dbSNP
rs1325738095 600 dbSNP
rs958928925 602 dbSNP
rs183943119 608 dbSNP
rs897522568 609 dbSNP
rs76814701 611 dbSNP
rs1467969772 612 dbSNP
rs941957269 613 dbSNP
rs909018003 614 dbSNP
rs1249621025 616 dbSNP
rs1475308707 618 dbSNP
rs1212208416 622 dbSNP
rs951777641 626 dbSNP
rs532343123 627 dbSNP
rs1164782525 628 dbSNP
rs186768006 633 dbSNP
rs769894294 639 dbSNP
rs550203824 643 dbSNP
rs1191066354 650 dbSNP
rs547903289 655 dbSNP
rs993221086 657 dbSNP
rs921330555 664 dbSNP
rs897586684 667 dbSNP
rs1361767461 671 dbSNP
rs1228968862 674 dbSNP
rs147689040 690 dbSNP
rs1315385385 691 dbSNP
rs561383255 693 dbSNP
rs1008710041 698 dbSNP
rs889029642 699 dbSNP
rs988374877 700 dbSNP
rs541204039 701 dbSNP
rs183196074 703 dbSNP
rs1406563357 705 dbSNP
rs1398637843 706 dbSNP
rs538745307 710 dbSNP
rs565388058 710 dbSNP
rs1469609418 715 dbSNP
rs1335062788 719 dbSNP
rs1002353487 720 dbSNP
rs1449346493 723 dbSNP
rs1279077220 727 dbSNP
rs1338513393 729 dbSNP
rs969571414 730 dbSNP
rs1289212129 731 dbSNP
rs1323014760 736 dbSNP
rs1295240024 739 dbSNP
rs1260965540 749 dbSNP
rs190577005 752 dbSNP
rs925939617 755 dbSNP
rs1210694236 772 dbSNP
rs866866578 776 dbSNP
rs1365286614 783 dbSNP
rs11939884 784 dbSNP
rs946125683 792 dbSNP
rs1449862210 793 dbSNP
rs917365889 796 dbSNP
rs4148312 801 dbSNP
rs1409689683 802 dbSNP
rs1036447390 804 dbSNP
rs546638333 805 dbSNP
rs185812401 811 dbSNP
rs1352903480 813 dbSNP
rs927520669 815 dbSNP
rs1171025357 816 dbSNP
rs1288999985 817 dbSNP
rs1345136728 820 dbSNP
rs1221876275 822 dbSNP
rs1272904041 827 dbSNP
rs984354811 831 dbSNP
rs953078218 841 dbSNP
rs549237261 848 dbSNP
rs1272199750 854 dbSNP
rs1310773976 855 dbSNP
rs1430990638 858 dbSNP
rs757052507 859 dbSNP
rs751488861 860 dbSNP
rs1181783948 868 dbSNP
rs145487721 869 dbSNP
rs961804323 887 dbSNP
rs1308253376 890 dbSNP
rs1478557934 891 dbSNP
rs1167630746 892 dbSNP
rs1018690177 896 dbSNP
rs1418005929 904 dbSNP
rs1432111543 910 dbSNP
rs1308743700 918 dbSNP
rs543997228 920 dbSNP
rs1041096716 923 dbSNP
rs1181379324 924 dbSNP
rs1403394074 927 dbSNP
rs1437004353 933 dbSNP
rs763975351 937 dbSNP
rs913874438 938 dbSNP
rs1207175162 940 dbSNP
rs1269320569 952 dbSNP
rs373382650 956 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 10941.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000503640.1 | 3UTR | AAGAUUUGGGUACUGUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
134 hsa-miR-4477a Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055843 PLEKHA1 pleckstrin homology domain containing A1 2 10
MIRT061259 AMOTL1 angiomotin like 1 2 4
MIRT071895 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT076933 MLLT6 MLLT6, PHD finger containing 2 2
MIRT078652 ICT1 mitochondrial ribosomal protein L58 2 2
MIRT083633 PRNP prion protein 2 2
MIRT091629 RPL15 ribosomal protein L15 2 4
MIRT107076 PPP6C protein phosphatase 6 catalytic subunit 2 2
MIRT111191 TRIM33 tripartite motif containing 33 2 2
MIRT114515 ARF6 ADP ribosylation factor 6 2 2
MIRT175250 PSAT1 phosphoserine aminotransferase 1 2 4
MIRT175430 ACSL4 acyl-CoA synthetase long chain family member 4 2 2
MIRT178687 FAM102B family with sequence similarity 102 member B 2 2
MIRT189771 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT229450 RPL10 ribosomal protein L10 2 2
MIRT244899 PHF6 PHD finger protein 6 2 2
MIRT249189 AKIRIN1 akirin 1 2 8
MIRT261134 TRIM8 tripartite motif containing 8 2 2
MIRT275561 ZIC5 Zic family member 5 2 4
MIRT275652 ABHD13 abhydrolase domain containing 13 2 2
MIRT288082 UTP18 UTP18, small subunit processome component 2 2
MIRT303605 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT307924 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT316787 FOXC1 forkhead box C1 2 2
MIRT326910 SCML2 Scm polycomb group protein like 2 2 2
MIRT327713 SPIN4 spindlin family member 4 2 2
MIRT331632 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 2
MIRT342506 TMOD3 tropomodulin 3 2 4
MIRT354470 LRRC58 leucine rich repeat containing 58 2 2
MIRT378711 TRIM24 tripartite motif containing 24 2 2
MIRT407462 YDJC YdjC chitooligosaccharide deacetylase homolog 2 2
MIRT408226 SMAD5 SMAD family member 5 2 4
MIRT441824 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT442783 CHD8 chromodomain helicase DNA binding protein 8 2 2
MIRT443184 NHS NHS actin remodeling regulator 2 4
MIRT447615 CUL3 cullin 3 2 2
MIRT450156 DSEL dermatan sulfate epimerase-like 2 2
MIRT454801 NEDD9 neural precursor cell expressed, developmentally down-regulated 9 2 2
MIRT463050 ZNF644 zinc finger protein 644 2 2
MIRT467400 SOCS3 suppressor of cytokine signaling 3 2 2
MIRT468174 SGMS1 sphingomyelin synthase 1 2 2
MIRT468949 RPS14 ribosomal protein S14 2 6
MIRT469835 R3HDM4 R3H domain containing 4 2 2
MIRT470724 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT470902 PLIN3 perilipin 3 2 2
MIRT472467 NAPG NSF attachment protein gamma 2 12
MIRT472602 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 2
MIRT492350 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT493840 FOXN3 forkhead box N3 2 4
MIRT496318 DOCK9 dedicator of cytokinesis 9 2 2
MIRT500159 CLEC2D C-type lectin domain family 2 member D 2 8
MIRT500535 XPO4 exportin 4 2 4
MIRT503916 FBXL13 F-box and leucine rich repeat protein 13 2 4
MIRT504003 SAT1 spermidine/spermine N1-acetyltransferase 1 2 4
MIRT505647 SHMT1 serine hydroxymethyltransferase 1 2 4
MIRT506574 MIER3 MIER family member 3 2 4
MIRT506945 HS3ST3B1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 2 4
MIRT508196 RPS19 ribosomal protein S19 2 6
MIRT511417 HSPA13 heat shock protein family A (Hsp70) member 13 2 4
MIRT512326 ACTB actin beta 2 4
MIRT515376 RPL7 ribosomal protein L7 2 2
MIRT520422 TUBG1 tubulin gamma 1 2 4
MIRT524844 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT526320 UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus 2 2
MIRT526561 UGT2A2 UDP glucuronosyltransferase family 2 member A2 2 2
MIRT528027 FEZ2 fasciculation and elongation protein zeta 2 2 2
MIRT529874 RBM43 RNA binding motif protein 43 2 2
MIRT530826 CLEC4D C-type lectin domain family 4 member D 2 2
MIRT531334 GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 2 2
MIRT532068 CCNB1 cyclin B1 2 4
MIRT532870 ZNF566 zinc finger protein 566 2 2
MIRT535580 NUP35 nucleoporin 35 2 2
MIRT537644 ERGIC2 ERGIC and golgi 2 2 4
MIRT537725 ELAVL2 ELAV like RNA binding protein 2 2 2
MIRT538894 BRI3BP BRI3 binding protein 2 2
MIRT538945 BMP2K BMP2 inducible kinase 2 2
MIRT540703 PDPK1 3-phosphoinositide dependent protein kinase 1 2 4
MIRT543210 TMEM117 transmembrane protein 117 2 3
MIRT543357 LYRM2 LYR motif containing 2 2 2
MIRT544905 CLSPN claspin 2 2
MIRT545532 ARF3 ADP ribosylation factor 3 2 2
MIRT546446 SMOC1 SPARC related modular calcium binding 1 2 2
MIRT546882 PURB purine rich element binding protein B 2 4
MIRT547440 MED13 mediator complex subunit 13 2 2
MIRT548027 GOLIM4 golgi integral membrane protein 4 2 2
MIRT548673 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT550435 LLGL2 LLGL2, scribble cell polarity complex component 2 2
MIRT551850 RPS3 ribosomal protein S3 2 2
MIRT556072 MRFAP1 Morf4 family associated protein 1 2 2
MIRT556554 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT557132 HOXA13 homeobox A13 2 2
MIRT557875 FEM1B fem-1 homolog B 2 4
MIRT558146 ELK4 ELK4, ETS transcription factor 2 2
MIRT558862 CD2AP CD2 associated protein 2 2
MIRT558884 CCNE1 cyclin E1 2 4
MIRT558907 CBX5 chromobox 5 2 2
MIRT559175 BRAP BRCA1 associated protein 2 2
MIRT560860 GAL3ST3 galactose-3-O-sulfotransferase 3 2 2
MIRT561729 PPIF peptidylprolyl isomerase F 2 2
MIRT564024 CEBPB CCAAT/enhancer binding protein beta 2 2
MIRT564366 TRMT5 tRNA methyltransferase 5 2 2
MIRT564609 ZNF703 zinc finger protein 703 2 2
MIRT565494 AZF1 azoospermia factor 1 2 2
MIRT565577 SLC6A8 solute carrier family 6 member 8 2 2
MIRT566947 LEPROT leptin receptor overlapping transcript 2 2
MIRT567293 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT567308 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT568048 CHSY1 chondroitin sulfate synthase 1 2 2
MIRT571807 PHF19 PHD finger protein 19 2 2
MIRT609234 RBM23 RNA binding motif protein 23 2 2
MIRT610328 SSX5 SSX family member 5 2 2
MIRT611428 UGT8 UDP glycosyltransferase 8 2 4
MIRT611709 SLFN13 schlafen family member 13 2 2
MIRT612069 CEP135 centrosomal protein 135 2 4
MIRT617676 JRKL JRK like 2 2
MIRT623684 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT635634 PRR15L proline rich 15 like 2 2
MIRT636422 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT637011 GPATCH11 G-patch domain containing 11 2 2
MIRT644150 C4orf3 chromosome 4 open reading frame 3 2 2
MIRT648562 MEMO1 mediator of cell motility 1 2 2
MIRT650752 WNT16 Wnt family member 16 2 2
MIRT651914 UEVLD UEV and lactate/malate dehyrogenase domains 2 2
MIRT653556 SLC38A7 solute carrier family 38 member 7 2 2
MIRT692277 XRN2 5'-3' exoribonuclease 2 2 2
MIRT697650 WNK1 WNK lysine deficient protein kinase 1 2 2
MIRT703876 ERCC6 ERCC excision repair 6, chromatin remodeling factor 2 2
MIRT704615 CLIP1 CAP-Gly domain containing linker protein 1 2 2
MIRT708562 BBOX1 gamma-butyrobetaine hydroxylase 1 2 2
MIRT709614 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT712955 SGCD sarcoglycan delta 2 2
MIRT713502 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT720239 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT724255 GLUD1 glutamate dehydrogenase 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4477a Imatinib 5291 NSC743414 approved sensitive High Gastrointestinal Stromal Tumor cell line (882R-NC, 882R-OE, 882R-KD)
hsa-miR-4477a Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-4477a Vemurafenib 42611257 NSC761431 approved resistant cell line (451Lu)

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