miRTarBase - #MIRT526995


—
pre-miRNA Information
pre-miRNA hsa-mir-3120   
Genomic Coordinates chr1: 172138808 - 172138888
Description Homo sapiens miR-3120 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3120-5p
Sequence 13| CCUGUCUGUGCCUGCUGUACA |33
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 19 1 + 172138838 26449202, 27587585 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN26637643 8 COSMIC
COSN31603497 11 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs750386761 8 dbSNP
rs760725207 9 dbSNP
rs766486759 10 dbSNP
rs754055278 12 dbSNP
rs755288536 19 dbSNP
rs754726014 21 dbSNP
Putative Targets

Gene Information
Gene Symbol ARL8B   
Synonyms ARL10C, Gie1
Description ADP ribosylation factor like GTPase 8B
Transcript NM_018184   
Expression
Putative miRNA Targets on ARL8B
3'UTR of ARL8B
(miRNA target sites are highlighted)		 
>ARL8B|NM_018184|3'UTR
   1 AGCATCTCCTGAAGTCTTCCAGTCCTTCTTGGCTATAATCCTAGAATTATTGTCCGTTCCTCTGAAGTAATTCCCAGAAT
  81 ACGGTCCTTCCTAAACCCCAGAAATTGCCTTTTTCAGAGTTTATTTCTCATGTGCACTGCTGAAGATGAATATCCCTAAT
 161 CCTTCATAAAGAATCAGCTAGAGTTGTCATGATAAAGTCAGCACACACAAAAAGGCTTCTTACACATACCTGTCTTAAAC
 241 CATGTGTAGAGCTTTAAAAACAGAAAAAAAACCCCATATACTTATGACCATCTTAAATCAAGAAAATTGCATATTTCCAT
 321 TCTGGTCTTTCTGGGCCAGATTTTTATATTGGTTTTCAGTAAATGTCTATCTATAATATTTCATTATAGAGTCCAGTAGC
 401 TTAATACTGACACTGACTTGATACAGCATGAAGTTTCTAGTGCCACACACAGTATTTAGAAAACCTTTAGGCGTGAATGA
 481 CTCATGTGGGATATATGTAAACATAATGTTTATTTTATCTCACAAATGCATGTGAAATGTATAATTACATCTTAGGAATC
 561 CAAAATGGTCTGCAGAGAGTGAGCGGAGGCACCAGATCAATGTTGGTTCTTTGCACTGGTGAGATTCTGCCTGATGAATA
 641 TTAAAGATATCCTGCTTTCTGAGAACTCTATCACCAGATGGCAGTTGGGATATGGGAGGAACTAAAGCATCCTGTTTTGT
 721 ATCTGTCCAGATCATTATTTCTGTCTCTTGTTTTTTCTTCCTGGTTCAGGATACTTTTTTAAGGGGTTGAGAATTGAAGA
 801 TTTTCCAAAAGCGTTCATGAATTTAGAGCATTCCACCCAATATAATAAAACCTGTTAAGAATGTCAGTCTTTGTTCAAAC
 881 ATCTGTTTGTTCTATCTCCAGTCATTAAATCAGTGCTGCTGCATGACACTCTTAACTCCTGACTTTTTATATCCAGTCAT
 961 AAAGTTGACTTTCAGCACAAAAGATACTTATAAACAAATAAAAAATTTTTATTTTTCTCTCTTACTGATGTAAGCTTTGG
1041 CACTCTTTTGACTGGTGCCATTAGACATCTTGATTATTGTGACAACTCTAGACCTGCCTGCTTTATCTAATGTAATCATG
1121 CTCAATGTCTACAGGTTGTTTAATAATCAGTCACACAGAGAACTGAGGAACTGATGCTGTTTGTTTGCTTCTATGATACA
1201 GAGATGTCTAAAAACTTCAAATGGACATGTTTTGTAGTTTAGCGACTTCCGTATACATAAAGGGACATATTAATACTGGT
1281 TCATTTGTAAATTATTATTCATATAGACCACTGTAGTAGATAAAACTCTATGGTACACCTGCTTATGTGTTGCCTCACAC
1361 TGTGTGTGATTTTGTTTCTTTTGTTAAGCAGCACTTATGTAGACTGCATTTCCAAATGTGTTGAGCACTCAGAGTGTAGT
1441 CAACAGTAAGTTCTTTTAATGAATATCAGTTTTAATTTATAGACTGCCATGGCCTTAAAAATATTCTGTACAATATACTG
1521 CACTGTGTTGCACAGACACTACTTGCTTTTCTCCATTCATATTTTTATGAGTAGAATCTGGGCTTTTAAATTTCTCTTCT
1601 TATTCTTTGAAGCATGTTGCATACTACCCTGGTGGGATGGATGGTTCTGTAAATGAAGGGATATTTAAACTTGCTACTGT
1681 TGTTCAACACCATTAATGGTCAGTGTGAACCATTACAAAGAATGTGGCAACTTGCTTGTGCCTAAAAGGAGGAATTGGAA
1761 CTAGAATGTGTGACTCTGTGGGGACTGCATAGGTTTGTTAATTGACCTATAGCTAAACCTTAATGTGTTTGTGTGTCTAT
1841 ACATTGCTTTCCGCATTTCAAGACATCCAGACGCTATTACCAACATTTTCCTGTGCATTAACCTCTGCATGTGAAAACTT
1921 TTAACAGTTACTGAACTATGTAAATATGTGAATTTTTTTATTTAGGTGGATGCATTTTTTGTCTGTTTACTGCTCTTCTC
2001 AGCTTTATTCAATAAACTTGCATTTTAAGGGTTGTATTGGCAATTTTAACTTAAAATGTGCATCATGATGGAAGGTGCAG
2081 ACTTTTTTGGAAGTTTCCGAGAGGAGGGTCTATAGACCATTTGTCAGAAATCAGATCAGCCCTCAAAGAATGGGGTCTGT
2161 GGGCTAGTTAAAATAGAAATAAACTTTTAAAATATCCACAGAAAAAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acAUGUCGU----C--CGUGUCUGUcc 5'
            ||| |||    |  |||||||||  
Target 5' taTACTGCACTGTGTTGCACAGACAct 3'
 1514 - 1540 143.00 -14.20
2 
miRNA  3' acaUGUCGUCCGUGUCUGucc 5'
             |::| |||::|||||   
Target 5' atgATGGAAGGTGCAGACttt 3'
 2065 - 2085 126.00 -12.52
3 
miRNA  3' acAUGUCGUCCGUGUCUGUCc 5'
            | :||: | |||| |||| 
Target 5' ttTCTAGT-GCCACACACAGt 3'
 434 - 453 126.00 -9.20
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM1593916 15 COSMIC
COSM1593915 22 COSMIC
COSM5202421 50 COSMIC
COSM9431309 55 COSMIC
COSN30113682 72 COSMIC
COSN30451157 76 COSMIC
COSN30184106 98 COSMIC
COSN16128965 176 COSMIC
COSN30131865 219 COSMIC
COSN29602730 272 COSMIC
COSN31562113 272 COSMIC
COSN20651111 273 COSMIC
COSN31491228 323 COSMIC
COSN31529196 351 COSMIC
COSN31541388 368 COSMIC
COSN26559831 378 COSMIC
COSN9721513 398 COSMIC
COSN25096991 747 COSMIC
COSN31544303 884 COSMIC
COSN31480593 1108 COSMIC
COSN31526403 1124 COSMIC
COSN31537742 1245 COSMIC
COSN16103289 1250 COSMIC
COSN26650545 1437 COSMIC
COSN5003393 1462 COSMIC
COSN19316671 1502 COSMIC
COSN22808319 1600 COSMIC
COSN31514774 1832 COSMIC
COSN7700479 1853 COSMIC
COSN31548178 1863 COSMIC
COSN31594829 1960 COSMIC
COSN20098077 2094 COSMIC
COSN31480768 2145 COSMIC
COSN31583237 2177 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs750841442 1 dbSNP
rs1161760516 2 dbSNP
rs1413366375 5 dbSNP
rs1406238159 18 dbSNP
rs758935284 19 dbSNP
rs1358752589 21 dbSNP
rs1399424924 22 dbSNP
rs780463626 23 dbSNP
rs752542985 25 dbSNP
rs1326884083 33 dbSNP
rs769135845 36 dbSNP
rs1282269154 39 dbSNP
rs752366624 40 dbSNP
rs777371699 41 dbSNP
rs748882799 53 dbSNP
rs1293463314 56 dbSNP
rs115131604 57 dbSNP
rs1188325004 62 dbSNP
rs1445550236 65 dbSNP
rs1258721560 72 dbSNP
rs1183195511 73 dbSNP
rs546288848 83 dbSNP
rs772026456 84 dbSNP
rs1449182748 85 dbSNP
rs775243372 90 dbSNP
rs760701634 91 dbSNP
rs1272303699 97 dbSNP
rs1445593146 100 dbSNP
rs764015795 101 dbSNP
rs776709830 103 dbSNP
rs762004962 106 dbSNP
rs1159268172 108 dbSNP
rs1387213487 109 dbSNP
rs1402442830 120 dbSNP
rs1383194505 137 dbSNP
rs940357578 139 dbSNP
rs1313802948 146 dbSNP
rs1379768732 151 dbSNP
rs1229989754 162 dbSNP
rs750495291 163 dbSNP
rs1394482568 166 dbSNP
rs1378784806 167 dbSNP
rs1040131258 203 dbSNP
rs901565194 211 dbSNP
rs56317680 223 dbSNP
rs1368801637 227 dbSNP
rs1168449620 230 dbSNP
rs1425876608 231 dbSNP
rs1370528188 236 dbSNP
rs758594013 240 dbSNP
rs1209524563 241 dbSNP
rs372987676 243 dbSNP
rs893390778 244 dbSNP
rs1011858835 246 dbSNP
rs1183036577 248 dbSNP
rs914499547 260 dbSNP
rs1241340243 261 dbSNP
rs188538987 262 dbSNP
rs181573664 263 dbSNP
rs1002841357 264 dbSNP
rs755510556 269 dbSNP
rs1035779793 272 dbSNP
rs562244007 273 dbSNP
rs1307896924 278 dbSNP
rs1458093868 280 dbSNP
rs1348660771 286 dbSNP
rs1307538041 289 dbSNP
rs1023499101 290 dbSNP
rs1406062880 306 dbSNP
rs541168998 307 dbSNP
rs1389797451 312 dbSNP
rs1161818952 334 dbSNP
rs1457660899 338 dbSNP
rs1364752244 340 dbSNP
rs1390356454 341 dbSNP
rs779700883 349 dbSNP
rs1409088027 366 dbSNP
rs1180892819 367 dbSNP
rs200903833 368 dbSNP
rs1269460645 369 dbSNP
rs984762608 370 dbSNP
rs907774259 371 dbSNP
rs1268555645 373 dbSNP
rs748564394 383 dbSNP
rs1230425185 392 dbSNP
rs574968021 393 dbSNP
rs1327398775 409 dbSNP
rs1450056439 421 dbSNP
rs1277706443 427 dbSNP
rs1372604251 429 dbSNP
rs1332910773 430 dbSNP
rs542626858 439 dbSNP
rs1386729510 450 dbSNP
rs1290032008 461 dbSNP
rs975678971 465 dbSNP
rs1321631191 470 dbSNP
rs769396441 473 dbSNP
rs1386077389 474 dbSNP
rs369812591 484 dbSNP
rs1478033522 486 dbSNP
rs1378877089 487 dbSNP
rs1432558329 488 dbSNP
rs931703971 489 dbSNP
rs1210415647 497 dbSNP
rs1050585193 501 dbSNP
rs1444207012 505 dbSNP
rs1202608214 507 dbSNP
rs893327478 509 dbSNP
rs947536019 511 dbSNP
rs1201259468 521 dbSNP
rs1232799153 530 dbSNP
rs1347151915 531 dbSNP
rs1273186544 540 dbSNP
rs1233125278 542 dbSNP
rs1366623047 545 dbSNP
rs866332461 562 dbSNP
rs1433434610 563 dbSNP
rs1360158475 564 dbSNP
rs1184745317 566 dbSNP
rs1427678215 571 dbSNP
rs903397486 574 dbSNP
rs772891078 575 dbSNP
rs1171651933 576 dbSNP
rs1170344619 577 dbSNP
rs1465468669 581 dbSNP
rs544385491 585 dbSNP
rs1035665788 586 dbSNP
rs1190434940 587 dbSNP
rs563868455 590 dbSNP
rs748773336 595 dbSNP
rs185862163 604 dbSNP
rs1410396194 606 dbSNP
rs77699050 614 dbSNP
rs1343432024 615 dbSNP
rs984994389 618 dbSNP
rs190919506 619 dbSNP
rs1277311020 621 dbSNP
rs1226858999 625 dbSNP
rs1223066662 634 dbSNP
rs1275661174 635 dbSNP
rs149189748 636 dbSNP
rs528879223 637 dbSNP
rs1347478667 640 dbSNP
rs759326584 647 dbSNP
rs1212862743 649 dbSNP
rs1285192441 651 dbSNP
rs1272429733 664 dbSNP
rs1448264983 666 dbSNP
rs1014794734 667 dbSNP
rs1331616561 669 dbSNP
rs1413556110 670 dbSNP
rs117819224 671 dbSNP
rs1170355550 683 dbSNP
rs1207950744 684 dbSNP
rs1427773029 688 dbSNP
rs1389285386 693 dbSNP
rs975732965 694 dbSNP
rs767505448 697 dbSNP
rs775099928 700 dbSNP
rs953142452 722 dbSNP
rs1200104311 724 dbSNP
rs1187116488 730 dbSNP
rs34105324 730 dbSNP
rs182631176 731 dbSNP
rs766777903 742 dbSNP
rs1478834310 744 dbSNP
rs914272999 751 dbSNP
rs947583020 751 dbSNP
rs1165616013 762 dbSNP
rs760581365 764 dbSNP
rs1230449769 765 dbSNP
rs1389041785 774 dbSNP
rs1282004858 775 dbSNP
rs1354689987 775 dbSNP
rs186302873 791 dbSNP
rs1042255442 793 dbSNP
rs1309361409 794 dbSNP
rs1430271337 800 dbSNP
rs1407898064 807 dbSNP
rs1353921933 812 dbSNP
rs1170425774 813 dbSNP
rs542488238 814 dbSNP
rs938946962 832 dbSNP
rs765528301 835 dbSNP
rs894521036 837 dbSNP
rs1428924919 839 dbSNP
rs572931584 844 dbSNP
rs750726405 857 dbSNP
rs1342981437 863 dbSNP
rs1247729823 868 dbSNP
rs1231169399 873 dbSNP
rs1289654131 874 dbSNP
rs1329490890 875 dbSNP
rs1290210000 882 dbSNP
rs1226111221 884 dbSNP
rs1048480054 885 dbSNP
rs1438553547 886 dbSNP
rs1359429844 893 dbSNP
rs1210786800 895 dbSNP
rs1325024842 896 dbSNP
rs551622386 898 dbSNP
rs1452931333 900 dbSNP
rs1006069385 904 dbSNP
rs1190602668 907 dbSNP
rs1425983439 915 dbSNP
rs1193387265 919 dbSNP
rs1014681997 920 dbSNP
rs961839623 924 dbSNP
rs1246812384 926 dbSNP
rs1209814387 932 dbSNP
rs997411531 932 dbSNP
rs1190012797 944 dbSNP
rs1269556378 948 dbSNP
rs796912475 948 dbSNP
rs1030201581 953 dbSNP
rs1315761261 954 dbSNP
rs1383284763 957 dbSNP
rs191037023 961 dbSNP
rs1220847981 962 dbSNP
rs986162378 969 dbSNP
rs1302403132 974 dbSNP
rs914346230 977 dbSNP
rs1367107411 979 dbSNP
rs1318726056 984 dbSNP
rs564019185 992 dbSNP
rs968844630 996 dbSNP
rs977157594 1000 dbSNP
rs1178383792 1001 dbSNP
rs1413253191 1007 dbSNP
rs763113793 1014 dbSNP
rs1189780902 1016 dbSNP
rs1366280687 1019 dbSNP
rs1451658575 1020 dbSNP
rs1246600683 1021 dbSNP
rs866574379 1024 dbSNP
rs1485365248 1027 dbSNP
rs183020948 1028 dbSNP
rs1340362503 1030 dbSNP
rs1246201602 1034 dbSNP
rs938830470 1038 dbSNP
rs1229076431 1042 dbSNP
rs553146456 1045 dbSNP
rs1343986695 1046 dbSNP
rs143418261 1051 dbSNP
rs1381840244 1053 dbSNP
rs1267551673 1058 dbSNP
rs535475138 1060 dbSNP
rs1057414769 1061 dbSNP
rs1206363262 1062 dbSNP
rs916129948 1067 dbSNP
rs1374941304 1070 dbSNP
rs948748861 1084 dbSNP
rs751669037 1101 dbSNP
rs1189907381 1115 dbSNP
rs1388737318 1122 dbSNP
rs1170124107 1123 dbSNP
rs187644975 1124 dbSNP
rs1256336434 1126 dbSNP
rs1183230168 1128 dbSNP
rs1484434568 1133 dbSNP
rs1256161003 1136 dbSNP
rs888551391 1139 dbSNP
rs1483968505 1145 dbSNP
rs1249418505 1147 dbSNP
rs1226334219 1149 dbSNP
rs1423124379 1156 dbSNP
rs1188181684 1157 dbSNP
rs755387714 1166 dbSNP
rs1226798634 1171 dbSNP
rs1037057754 1177 dbSNP
rs897701460 1182 dbSNP
rs1308671484 1184 dbSNP
rs530511436 1185 dbSNP
rs1468407185 1188 dbSNP
rs1030209639 1194 dbSNP
rs1297966576 1198 dbSNP
rs1158217878 1200 dbSNP
rs1389623133 1201 dbSNP
rs1459054891 1207 dbSNP
rs1334740534 1210 dbSNP
rs1370545684 1217 dbSNP
rs1166526130 1223 dbSNP
rs781735988 1225 dbSNP
rs1474000192 1241 dbSNP
rs1416559428 1244 dbSNP
rs552164337 1245 dbSNP
rs953395202 1248 dbSNP
rs1397061352 1251 dbSNP
rs575511111 1252 dbSNP
rs1021739857 1256 dbSNP
rs1488712750 1267 dbSNP
rs1266954830 1268 dbSNP
rs1334574698 1269 dbSNP
rs544475820 1271 dbSNP
rs564356595 1274 dbSNP
rs968396810 1277 dbSNP
rs564076485 1289 dbSNP
rs1334375243 1293 dbSNP
rs577768060 1294 dbSNP
rs540369393 1297 dbSNP
rs1348700013 1305 dbSNP
rs1289416824 1310 dbSNP
rs1306980589 1313 dbSNP
rs1387830792 1314 dbSNP
rs1393373926 1318 dbSNP
rs559982200 1322 dbSNP
rs1329373182 1326 dbSNP
rs1210239986 1330 dbSNP
rs148364654 1331 dbSNP
rs992955250 1332 dbSNP
rs116458402 1335 dbSNP
rs1361536997 1337 dbSNP
rs562437441 1347 dbSNP
rs1200604735 1359 dbSNP
rs948954138 1361 dbSNP
rs984375989 1363 dbSNP
rs909897151 1369 dbSNP
rs1258163247 1381 dbSNP
rs1436056501 1382 dbSNP
rs1181146159 1387 dbSNP
rs940020487 1395 dbSNP
rs1348687855 1398 dbSNP
rs1037110091 1399 dbSNP
rs568746271 1413 dbSNP
rs531652806 1425 dbSNP
rs752756123 1427 dbSNP
rs1301711340 1428 dbSNP
rs1473667222 1431 dbSNP
rs933173817 1435 dbSNP
rs1366362109 1436 dbSNP
rs4685885 1444 dbSNP
rs192648932 1454 dbSNP
rs1051518618 1460 dbSNP
rs1157430344 1485 dbSNP
rs888942030 1490 dbSNP
rs1379226163 1496 dbSNP
rs571471384 1506 dbSNP
rs1007915362 1511 dbSNP
rs1248381413 1512 dbSNP
rs1190790922 1516 dbSNP
rs1445448871 1518 dbSNP
rs183387729 1524 dbSNP
rs188075747 1531 dbSNP
rs1201044363 1534 dbSNP
rs1347214732 1537 dbSNP
rs1278886906 1540 dbSNP
rs1343367638 1541 dbSNP
rs756519543 1545 dbSNP
rs1432485309 1551 dbSNP
rs1324259960 1552 dbSNP
rs1317021909 1553 dbSNP
rs1396169988 1554 dbSNP
rs1403699364 1555 dbSNP
rs1021541990 1560 dbSNP
rs1433986781 1561 dbSNP
rs192599834 1563 dbSNP
rs1170188040 1573 dbSNP
rs1436665264 1584 dbSNP
rs566837351 1595 dbSNP
rs749698073 1595 dbSNP
rs1394931580 1600 dbSNP
rs1188492930 1609 dbSNP
rs565058807 1620 dbSNP
rs777389094 1621 dbSNP
rs535871242 1622 dbSNP
rs1031427105 1627 dbSNP
rs1255449228 1629 dbSNP
rs555364491 1630 dbSNP
rs1352733923 1632 dbSNP
rs1277226866 1643 dbSNP
rs758516797 1649 dbSNP
rs993007385 1660 dbSNP
rs1269285637 1662 dbSNP
rs1311312994 1668 dbSNP
rs1233309535 1678 dbSNP
rs1023583744 1688 dbSNP
rs1482007199 1700 dbSNP
rs1204376449 1702 dbSNP
rs1414110850 1706 dbSNP
rs1371021667 1714 dbSNP
rs374084151 1724 dbSNP
rs1408060506 1732 dbSNP
rs984817673 1761 dbSNP
rs770576424 1764 dbSNP
rs910127935 1769 dbSNP
rs1415799056 1774 dbSNP
rs1297815903 1775 dbSNP
rs1266917489 1777 dbSNP
rs1473206398 1789 dbSNP
rs1254674020 1791 dbSNP
rs546397219 1792 dbSNP
rs1290991241 1796 dbSNP
rs1210090174 1799 dbSNP
rs972686652 1810 dbSNP
rs1212479273 1818 dbSNP
rs568227852 1820 dbSNP
rs922703062 1823 dbSNP
rs1178277445 1825 dbSNP
rs1371430495 1830 dbSNP
rs745406939 1831 dbSNP
rs575201045 1834 dbSNP
rs1169791602 1840 dbSNP
rs1373023348 1841 dbSNP
rs1392469099 1844 dbSNP
rs1403480891 1844 dbSNP
rs1457886857 1846 dbSNP
rs1410217638 1852 dbSNP
rs538150637 1853 dbSNP
rs1470033054 1854 dbSNP
rs1247674495 1867 dbSNP
rs888989668 1873 dbSNP
rs977265584 1880 dbSNP
rs1467415912 1890 dbSNP
rs1387021232 1891 dbSNP
rs1212660184 1892 dbSNP
rs1329291076 1894 dbSNP
rs377536139 1898 dbSNP
rs1285702519 1904 dbSNP
rs1302695534 1917 dbSNP
rs1222028709 1919 dbSNP
rs1339466621 1924 dbSNP
rs141156549 1937 dbSNP
rs577856764 1939 dbSNP
rs1368495506 1940 dbSNP
rs1043375839 1943 dbSNP
rs1436043579 1946 dbSNP
rs904399510 1948 dbSNP
rs1400644596 1951 dbSNP
rs1176065607 1953 dbSNP
rs1426571702 1953 dbSNP
rs1344303499 1961 dbSNP
rs1219072846 1963 dbSNP
rs775541692 1974 dbSNP
rs1252728208 1975 dbSNP
rs1192652089 1984 dbSNP
rs540453655 1986 dbSNP
rs1243358756 1987 dbSNP
rs1212949556 1994 dbSNP
rs895469133 1996 dbSNP
rs535315996 2013 dbSNP
rs1345513802 2015 dbSNP
rs142839616 2020 dbSNP
rs1022710653 2022 dbSNP
rs1436109928 2023 dbSNP
rs1364272498 2027 dbSNP
rs146922203 2033 dbSNP
rs137883539 2035 dbSNP
rs1359793395 2040 dbSNP
rs56118283 2053 dbSNP
rs1315413980 2061 dbSNP
rs1433359575 2063 dbSNP
rs149345761 2084 dbSNP
rs1017624630 2087 dbSNP
rs143599604 2091 dbSNP
rs59759123 2091 dbSNP
rs147463902 2092 dbSNP
rs1392547138 2094 dbSNP
rs961579964 2099 dbSNP
rs972946461 2108 dbSNP
rs922629855 2109 dbSNP
rs1279352084 2114 dbSNP
rs1164465841 2117 dbSNP
rs1309028867 2119 dbSNP
rs1293770164 2120 dbSNP
rs1214175794 2139 dbSNP
rs1380020867 2149 dbSNP
rs1295153163 2152 dbSNP
rs1413487084 2155 dbSNP
rs955374222 2167 dbSNP
rs1309169923 2168 dbSNP
rs147163933 2174 dbSNP
rs1353093844 2184 dbSNP
rs1167924493 2185 dbSNP
rs911277505 2196 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 55207.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acaUGUCGUCC-------GU---GUCUGUCc 5'
             | ||||||       ||   :|||||| 
Target 5' ---AAAGCAGGUCAUUGUCAUGGUAGACAGa 3'
 		1 - 28
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000419534.2 | 3UTR | AAAGCAGGUCAUUGUCAUGGUAGACAGAC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
134 hsa-miR-3120-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT096972 BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 2 2
MIRT442624 LOX lysyl oxidase 2 2
MIRT473438 MDM4 MDM4, p53 regulator 2 2
MIRT490011 KIFC2 kinesin family member C2 2 2
MIRT496449 N6AMT1 N-6 adenine-specific DNA methyltransferase 1 2 2
MIRT496752 TGIF2 TGFB induced factor homeobox 2 2 2
MIRT497721 CYP1A1 cytochrome P450 family 1 subfamily A member 1 2 2
MIRT498287 PADI3 peptidyl arginine deiminase 3 2 2
MIRT503195 ACVR1B activin A receptor type 1B 2 4
MIRT504760 TEP1 telomerase associated protein 1 2 4
MIRT517810 UGDH UDP-glucose 6-dehydrogenase 2 6
MIRT519686 ZNF622 zinc finger protein 622 2 4
MIRT520263 URGCP upregulator of cell proliferation 2 2
MIRT523051 ICMT isoprenylcysteine carboxyl methyltransferase 2 2
MIRT525601 OLR1 oxidized low density lipoprotein receptor 1 2 4
MIRT526995 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT528699 TRAF3IP2 TRAF3 interacting protein 2 2 4
MIRT533142 WNT10A Wnt family member 10A 2 2
MIRT537618 ERI1 exoribonuclease 1 2 2
MIRT539707 EIF3H eukaryotic translation initiation factor 3 subunit H 2 2
MIRT539752 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT539808 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT539941 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT540424 FAM83F family with sequence similarity 83 member F 2 2
MIRT540509 CXCL10 C-X-C motif chemokine ligand 10 2 2
MIRT540720 GUF1 GUF1 homolog, GTPase 2 2
MIRT541630 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT542286 POLR3K RNA polymerase III subunit K 2 2
MIRT542456 AKR7A2 aldo-keto reductase family 7 member A2 2 2
MIRT542550 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542771 PPAP2B phospholipid phosphatase 3 2 2
MIRT550085 TRAPPC2 trafficking protein particle complex 2 2 2
MIRT551458 CARKD NAD(P)HX dehydratase 2 2
MIRT555622 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT569136 KATNAL1 katanin catalytic subunit A1 like 1 2 2
MIRT572328 HSPB6 heat shock protein family B (small) member 6 2 2
MIRT574607 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT575583 Mcm8 minichromosome maintenance 8 homologous recombination repair factor 2 4
MIRT576125 Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 2 5
MIRT576657 Fam216a family with sequence similarity 216, member A 2 2
MIRT607222 ACSM2A acyl-CoA synthetase medium chain family member 2A 2 4
MIRT607292 CD300E CD300e molecule 2 6
MIRT607746 ANGPT4 angiopoietin 4 2 2
MIRT607905 SPRYD4 SPRY domain containing 4 2 2
MIRT608159 HRK harakiri, BCL2 interacting protein 2 7
MIRT608657 ABCF3 ATP binding cassette subfamily F member 3 2 4
MIRT609115 ZNF703 zinc finger protein 703 2 6
MIRT610231 ACOT9 acyl-CoA thioesterase 9 2 2
MIRT610870 NUDCD3 NudC domain containing 3 2 2
MIRT611217 MC2R melanocortin 2 receptor 2 2
MIRT614858 PLEKHA6 pleckstrin homology domain containing A6 2 2
MIRT616966 LMX1A LIM homeobox transcription factor 1 alpha 2 2
MIRT617258 GLIPR1L2 GLI pathogenesis related 1 like 2 2 2
MIRT618009 SLC9A3R2 SLC9A3 regulator 2 2 2
MIRT619067 BSND barttin CLCNK type accessory beta subunit 2 4
MIRT619295 FAM26E calcium homeostasis modulator family member 5 2 2
MIRT619348 GINM1 glycoprotein integral membrane 1 2 2
MIRT619362 CFHR5 complement factor H related 5 2 2
MIRT619541 PIWIL2 piwi like RNA-mediated gene silencing 2 2 2
MIRT619782 NRIP2 nuclear receptor interacting protein 2 2 2
MIRT619994 NPAP1 nuclear pore associated protein 1 2 2
MIRT621030 CDC14B cell division cycle 14B 2 2
MIRT622033 STAT5A signal transducer and activator of transcription 5A 2 2
MIRT622728 PITPNM3 PITPNM family member 3 2 2
MIRT623144 NAV2 neuron navigator 2 2 2
MIRT623600 IPO9 importin 9 2 2
MIRT624608 B3GALT5 beta-1,3-galactosyltransferase 5 2 2
MIRT624905 CTCFL CCCTC-binding factor like 2 2
MIRT625030 SPC24 SPC24, NDC80 kinetochore complex component 2 2
MIRT625688 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 5
MIRT626531 EMCN endomucin 2 2
MIRT627204 ZDHHC20 zinc finger DHHC-type containing 20 2 2
MIRT628033 LSAMP limbic system-associated membrane protein 2 2
MIRT628203 FREM2 FRAS1 related extracellular matrix protein 2 2 2
MIRT631012 LINS lines homolog 1 2 2
MIRT633195 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT633890 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT634023 MOB4 MOB family member 4, phocein 2 2
MIRT634416 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT636866 ARSE arylsulfatase E (chondrodysplasia punctata 1) 2 2
MIRT642527 ANKRD9 ankyrin repeat domain 9 2 2
MIRT645408 FAM110A family with sequence similarity 110 member A 2 2
MIRT645635 SYTL4 synaptotagmin like 4 2 2
MIRT646013 TNFAIP8L2 TNF alpha induced protein 8 like 2 2 2
MIRT646686 ASGR2 asialoglycoprotein receptor 2 2 2
MIRT652838 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT655156 PHF21B PHD finger protein 21B 2 2
MIRT658491 EXOC7 exocyst complex component 7 2 2
MIRT659398 CORO2A coronin 2A 2 2
MIRT666825 PRCP prolylcarboxypeptidase 2 2
MIRT666866 POU2F2 POU class 2 homeobox 2 2 2
MIRT668224 GABRA1 gamma-aminobutyric acid type A receptor alpha1 subunit 2 2
MIRT673288 PDE3A phosphodiesterase 3A 2 2
MIRT673878 KLF2 Kruppel like factor 2 2 2
MIRT681721 KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 2 2
MIRT682406 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT684109 MCM10 minichromosome maintenance 10 replication initiation factor 2 2
MIRT684423 TUFT1 tuftelin 1 2 2
MIRT684684 OR7D2 olfactory receptor family 7 subfamily D member 2 2 2
MIRT686638 TMEM184C transmembrane protein 184C 2 2
MIRT689457 NXN nucleoredoxin 2 2
MIRT689627 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT690773 PLA2G2C phospholipase A2 group IIC 2 2
MIRT690822 SGSM2 small G protein signaling modulator 2 2 2
MIRT693669 MXRA7 matrix remodeling associated 7 2 2
MIRT695553 CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2 2
MIRT695872 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT698160 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT699933 RUFY2 RUN and FYVE domain containing 2 2 2
MIRT708639 UBE2W ubiquitin conjugating enzyme E2 W 2 2
MIRT710816 RAB11FIP4 RAB11 family interacting protein 4 2 2
MIRT711242 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT711542 MSH3 mutS homolog 3 2 2
MIRT711749 DTX1 deltex E3 ubiquitin ligase 1 2 2
MIRT712303 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT712922 RPF2 ribosome production factor 2 homolog 2 2
MIRT714027 SYDE2 synapse defective Rho GTPase homolog 2 2 2
MIRT714768 TERF1 telomeric repeat binding factor 1 2 2
MIRT714844 ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 2 2
MIRT715223 NPVF neuropeptide VF precursor 2 2
MIRT716110 GMPS guanine monophosphate synthase 2 2
MIRT716174 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT716383 C6orf223 chromosome 6 open reading frame 223 2 2
MIRT716527 KSR2 kinase suppressor of ras 2 2 2
MIRT716962 P2RY6 pyrimidinergic receptor P2Y6 2 2
MIRT717605 DSTYK dual serine/threonine and tyrosine protein kinase 2 2
MIRT717696 PTGS1 prostaglandin-endoperoxide synthase 1 2 2
MIRT721360 ENTHD1 ENTH domain containing 1 2 2
MIRT721381 MACC1 MACC1, MET transcriptional regulator 2 2
MIRT721935 RASSF2 Ras association domain family member 2 2 2
MIRT722094 SUSD1 sushi domain containing 1 2 2
MIRT722837 C17orf102 chromosome 17 open reading frame 102 2 2
MIRT722990 TOR1A torsin family 1 member A 2 2
MIRT724174 ABCF2 ATP binding cassette subfamily F member 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3120-5p Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-3120-5p Prednisone/Azathioprine/Methotrexate/Cyclophosphamide/Mycophenolate mofetil sensitive tissue (myasthenia gravis)
hsa-miR-3120-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

Error report submission