pre-miRNA Information
pre-miRNA hsa-mir-3160-1   
Genomic Coordinates chr11: 46451805 - 46451889
Description Homo sapiens miR-3160-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-3160-2   
Genomic Coordinates chr11: 46451807 - 46451887
Description Homo sapiens miR-3160-2 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3160-3p
Sequence 54| AGAGCUGAGACUAGAAAGCCCA |75
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30582333 1 COSMIC
COSN1535547 3 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1396368683 1 dbSNP
rs1162409303 2 dbSNP
rs1404378453 12 dbSNP
rs1171960732 14 dbSNP
rs1324633375 16 dbSNP
rs1187765019 16 dbSNP
rs1300058326 19 dbSNP
rs1432898407 21 dbSNP
rs1011279103 22 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CLEC12B   
Synonyms UNQ5782
Description C-type lectin domain family 12 member B
Transcript NM_205852   
Other Transcripts NM_001129998   
Expression
Putative miRNA Targets on CLEC12B
3'UTR of CLEC12B
(miRNA target sites are highlighted)
>CLEC12B|NM_205852|3'UTR
   1 GGGTAAACACAAGCTTTCCATGGAATCCTGGGAAAATTAATAATGATTGTGAGAATTATAAATACAGACATAAAAAGAGG
  81 AGTACAACATACTGAGAAAAGAGCTCCAGTAACAAATATTGAAAGGAGGTATAGTTCATTTCATCTCTGTGACAAATTTA
 161 TAGCAAGGCACTGAATTTTATCTTTTGGTAGAAATGTGTTTATTTAACACACACACACACCTAATACTACATTCAAAGTA
 241 TTTTATAAATACTAACCCTTGAAGAAAGCAGTTATATTCCCATTTTATAGGTAGAAATATTATAATAGAGAGATTAAGTA
 321 ACTTGCCTGAGGTCACTCAGCTCATAAATTGCACTTTAGGGATTGTGCACTCAGTCACTCAGCTATTCTGACTCTCCAGC
 401 ACCTACAATCCAAAAGGGTGCTGCTGGTCATAAGAACACATATCAACACATTTATTTATACTAAATAACTGTCAACCATT
 481 TTCTAACAAAAAGTAAGACTGAATTGACTGATTAGTTCAACAATTAGTGTCATGTTGAGGACTTGCCAATTACAATATAC
 561 GGCAAGTGTCTTTTATGAATTAAAATGAACTAAACCTTCCACTTCAGGGTTTGGATGAAACTATTTAAAGGACAAATAGA
 641 ATATATAACACTTGGAAAATTTCAATTTTTTTAACTATTTAAAGTTATGAAAAAATAGACGTCAACAAAAATGTGTAAGG
 721 GGATATTAGGTTTGCTAAATTCTTTCACAGACTATAAAACAAAAAATTTTGAGGAACACCTCTCATCATAACTACATTTA
 801 AATGAAACAACTGTATTAATATTTTAAATATAATAGTATTTTTCTATTAGATAAAATTTAAGATCTTTGGCATCTTAATG
 881 GATTTTTAAACTTTTTATTGATACATAAGAGATGTATATGTTTTGGGGTATATGTGATAATTTGATACATTCAGATAGTG
 961 TGTAAAGATCAAATAAGTGGAATTGGGATATCGATCACTTTAAATATTTATCTTTTCTTTATGCTAGGAGCATTCAAATT
1041 ATTATTTTCTCATTATTGTGAAATGTACAGTAGATTATTGTTAATTGTATTCACCCTAATAATCTATGAAACACTAGGTC
1121 TTACTTCTTCTATCTAACAGAATATTTGTATTCATAATGGCTTTTTATCTACCTTCCTCCCCCAACAAATCATTATCCAC
1201 CCCCCTCCCTCCTGTTTCACTCTTTAAAGCATGTTGTCAACGTTTTCTTAAACTGAATAATAATCACTCATCTTCTGTCA
1281 AAGATGCCATGCTTCAGCTGTGACTCAGCAGTTCCTTAAATCACAAACAATGGTAGGTCTATTATTTTCTCCCTGGATAC
1361 ACTTTATCTTCATCCATTTCCCAATGTTTTGTCATGGCTATTTCTACTCAAACACTAATCCCCCATTCTCTAATCACCAT
1441 TATTAATCATATCAAGTCAATTAGTTTGGTTTCACACTAATAATAATGACAAAAAGCACATGCAGAGTAATACACAAACA
1521 AAAAAAGTGACAGTTACTTTTTTGTGACAAGAGCAATATTGGGTATGAACTGATTAATATTAATCTGAGGTGTTGCTACT
1601 AGACTGAGGGTTTCCAGGAGTAGTACTATGACATCATGTAAACACATTCAGTTTTCATGTTGGAATCTAAGATGTGTCCC
1681 TTCTCCCAAAGGGATTTTAATCATTCTTGGCCTCTCTACTCACTCTTAATCAAAGTGTGGAGGAGGTGGCCCCCACAGCA
1761 GGGTTTGGAACCTACAGACCCTGGCCCCTGAGACATGCAGCTGTCAGACAAGCCAGCATGTCAAACACAGGTTAGAGAGA
1841 CTGAGCTTCCAGATTGCATAGCCATTTCCTTGACTACTGAGTAAAGGCCAAGGCTAAGATTTAGTAAGCCTAGCCCTGAA
1921 GCAAGCAAAGAATATGGCAGTGTAATGCAGGTCATTTAGAAAAAAACAATGTTGGGCACAAAGAAAATTTAGATCTGACA
2001 AGTATAATTTTCTAAAGACATTATTTCAGGATTAACATCAATTTCTTAGCAGAGGAAATGAATACTATTGTCAGAACCAT
2081 ATCTATATAGTCAATCATTTCCTCTTTTAACGTCTGTCTTGTTCTCTTTTTACCCACCACATATGTATAACTATGTGAAA
2161 AATTATATTTGTGCATAATAAAATGTGATAACTTTTTACAACAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' acccGAA-AGA--UCA--GAGUCGAGa 5'
              |||  ||  :||  |||||||| 
Target 5' gtaaCTTGCCTGAGGTCACTCAGCTCa 3'
318 - 344 150.00 -13.70
2
miRNA  3' accCGAAAGAUCA--GAGUCGAga 5'
             ||  || |||  |||||||  
Target 5' tgtGCACTC-AGTCACTCAGCTat 3'
364 - 386 136.00 -12.00
3
miRNA  3' acccgaAAGAU-CAGAGUCGAga 5'
                | | | | :||||||  
Target 5' caaagaTGCCATGCTTCAGCTgt 3'
1279 - 1301 124.00 -7.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30451183 2 COSMIC
COSN31956392 4 COSMIC
COSN31506426 29 COSMIC
COSN30513380 32 COSMIC
COSN31578057 33 COSMIC
COSN507631 68 COSMIC
COSN31507166 71 COSMIC
COSN507633 77 COSMIC
COSN30525720 130 COSMIC
COSN30106025 209 COSMIC
COSN5927916 291 COSMIC
COSN18930973 477 COSMIC
COSN30144536 1367 COSMIC
COSN24751307 1382 COSMIC
COSN21437056 1383 COSMIC
COSN5830792 1436 COSMIC
COSN27884331 1527 COSMIC
COSN26304766 1544 COSMIC
COSN25890517 1772 COSMIC
COSN25618983 1780 COSMIC
COSN5927919 1881 COSMIC
COSN30160674 2113 COSMIC
rs1054611 1817 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs762917656 2 dbSNP
rs764274926 9 dbSNP
rs1231206318 11 dbSNP
rs1260664072 23 dbSNP
rs751720828 24 dbSNP
rs1330104790 30 dbSNP
rs1489124271 31 dbSNP
rs1227951996 37 dbSNP
rs757506410 42 dbSNP
rs563573983 43 dbSNP
rs767867368 45 dbSNP
rs1369627463 48 dbSNP
rs1214687570 51 dbSNP
rs1175014991 54 dbSNP
rs1437982433 69 dbSNP
rs1400582392 72 dbSNP
rs968458521 101 dbSNP
rs918164327 103 dbSNP
rs949695155 111 dbSNP
rs1037033610 123 dbSNP
rs977113921 124 dbSNP
rs1395612579 129 dbSNP
rs1191891971 134 dbSNP
rs897198406 164 dbSNP
rs900144832 165 dbSNP
rs924311814 168 dbSNP
rs938333507 172 dbSNP
rs1447941250 180 dbSNP
rs1288525044 186 dbSNP
rs1353689209 194 dbSNP
rs1347876381 195 dbSNP
rs1304765816 199 dbSNP
rs1048467394 203 dbSNP
rs1437162200 207 dbSNP
rs887588910 207 dbSNP
rs1007361934 213 dbSNP
rs1362052603 214 dbSNP
rs117936789 215 dbSNP
rs10845019 219 dbSNP
rs1376051214 220 dbSNP
rs1178077549 222 dbSNP
rs1221764453 226 dbSNP
rs561520318 236 dbSNP
rs1186157578 237 dbSNP
rs533664439 238 dbSNP
rs1478303326 239 dbSNP
rs1045655568 241 dbSNP
rs1020583867 246 dbSNP
rs118186444 249 dbSNP
rs1485521412 256 dbSNP
rs1006338643 257 dbSNP
rs186030326 259 dbSNP
rs566843273 266 dbSNP
rs1305274584 272 dbSNP
rs1222709896 276 dbSNP
rs1036428432 281 dbSNP
rs377180681 289 dbSNP
rs1214644655 291 dbSNP
rs535449119 293 dbSNP
rs997510561 296 dbSNP
rs1030299279 303 dbSNP
rs1198149425 307 dbSNP
rs953421413 311 dbSNP
rs1007453976 313 dbSNP
rs959136577 323 dbSNP
rs1423707901 327 dbSNP
rs1460348395 328 dbSNP
rs990987371 329 dbSNP
rs779602955 340 dbSNP
rs1466178349 342 dbSNP
rs1426107109 353 dbSNP
rs494312 367 dbSNP
rs977166053 368 dbSNP
rs1257233930 371 dbSNP
rs924362718 373 dbSNP
rs1418307210 383 dbSNP
rs1232781575 386 dbSNP
rs190493547 395 dbSNP
rs537959085 397 dbSNP
rs547241038 404 dbSNP
rs992904882 406 dbSNP
rs1363706022 441 dbSNP
rs1232226179 444 dbSNP
rs1404240471 447 dbSNP
rs183383572 448 dbSNP
rs1314677565 455 dbSNP
rs1341175809 459 dbSNP
rs1389456523 461 dbSNP
rs1372571627 462 dbSNP
rs1419505182 464 dbSNP
rs1229650336 471 dbSNP
rs918549636 472 dbSNP
rs1447640575 484 dbSNP
rs1402468309 493 dbSNP
rs1163070469 505 dbSNP
rs773227544 510 dbSNP
rs1461176451 523 dbSNP
rs1369268635 531 dbSNP
rs915553130 536 dbSNP
rs948316337 540 dbSNP
rs1167398257 544 dbSNP
rs187919881 547 dbSNP
rs370426811 554 dbSNP
rs1417678870 555 dbSNP
rs1338917753 558 dbSNP
rs1045307219 561 dbSNP
rs909402614 562 dbSNP
rs942173554 564 dbSNP
rs866260378 568 dbSNP
rs1250537160 575 dbSNP
rs1212509515 577 dbSNP
rs1488642497 578 dbSNP
rs200130379 595 dbSNP
rs1266814391 601 dbSNP
rs1236678161 614 dbSNP
rs762264209 617 dbSNP
rs897920623 620 dbSNP
rs1242156718 622 dbSNP
rs942817633 625 dbSNP
rs1263325812 626 dbSNP
rs1324044770 627 dbSNP
rs769997671 631 dbSNP
rs1391783079 633 dbSNP
rs1295453507 635 dbSNP
rs375349035 640 dbSNP
rs997402795 649 dbSNP
rs1159803360 654 dbSNP
rs1442151806 660 dbSNP
rs1020900393 666 dbSNP
rs1192511722 666 dbSNP
rs1393806009 666 dbSNP
rs902149589 672 dbSNP
rs1202960169 675 dbSNP
rs1485429243 678 dbSNP
rs1286544508 691 dbSNP
rs577459638 695 dbSNP
rs12824889 697 dbSNP
rs1032036810 701 dbSNP
rs1021526103 702 dbSNP
rs763622127 711 dbSNP
rs1423980123 718 dbSNP
rs991012652 720 dbSNP
rs1303689575 724 dbSNP
rs1380691117 741 dbSNP
rs1159210938 757 dbSNP
rs1362327213 761 dbSNP
rs553814083 764 dbSNP
rs998640429 768 dbSNP
rs1421875644 770 dbSNP
rs766980070 780 dbSNP
rs573893201 790 dbSNP
rs774622144 806 dbSNP
rs771406989 812 dbSNP
rs1190381577 815 dbSNP
rs776878229 827 dbSNP
rs1263414922 835 dbSNP
rs1449015771 836 dbSNP
rs992560080 837 dbSNP
rs972986656 840 dbSNP
rs1317672291 845 dbSNP
rs1484537998 850 dbSNP
rs1023080041 864 dbSNP
rs1345829386 869 dbSNP
rs1257897546 873 dbSNP
rs969731676 878 dbSNP
rs1357706427 885 dbSNP
rs1340176738 888 dbSNP
rs1279055697 899 dbSNP
rs981468990 903 dbSNP
rs542213074 906 dbSNP
rs562516708 916 dbSNP
rs918852864 927 dbSNP
rs531427271 928 dbSNP
rs1404977194 932 dbSNP
rs1287397354 934 dbSNP
rs1353404484 938 dbSNP
rs545171604 956 dbSNP
rs952994310 958 dbSNP
rs984083715 984 dbSNP
rs145463425 993 dbSNP
rs972229019 994 dbSNP
rs919403002 995 dbSNP
rs933414933 996 dbSNP
rs1260432030 1009 dbSNP
rs1187987875 1014 dbSNP
rs1442686341 1038 dbSNP
rs1444132709 1052 dbSNP
rs1051845524 1059 dbSNP
rs889140817 1060 dbSNP
rs1194202624 1069 dbSNP
rs1240833287 1069 dbSNP
rs942765700 1074 dbSNP
rs1041528798 1078 dbSNP
rs923104090 1078 dbSNP
rs759500621 1079 dbSNP
rs1284043743 1088 dbSNP
rs1245944671 1092 dbSNP
rs1443812590 1101 dbSNP
rs12825730 1116 dbSNP
rs1342833231 1122 dbSNP
rs564536384 1124 dbSNP
rs933161399 1129 dbSNP
rs1451525366 1149 dbSNP
rs943384132 1154 dbSNP
rs1042989907 1159 dbSNP
rs904449994 1167 dbSNP
rs1163670150 1180 dbSNP
rs1473644716 1182 dbSNP
rs191103197 1187 dbSNP
rs371096584 1192 dbSNP
rs1031477311 1199 dbSNP
rs1053443794 1200 dbSNP
rs894813823 1200 dbSNP
rs1470452438 1201 dbSNP
rs1338967371 1202 dbSNP
rs1011961733 1203 dbSNP
rs895635606 1204 dbSNP
rs533113205 1205 dbSNP
rs1239981525 1206 dbSNP
rs970893466 1206 dbSNP
rs1378282592 1208 dbSNP
rs1310905454 1221 dbSNP
rs1014443295 1222 dbSNP
rs994283124 1237 dbSNP
rs1025793144 1241 dbSNP
rs779525070 1256 dbSNP
rs547188797 1271 dbSNP
rs1157987197 1282 dbSNP
rs567024838 1286 dbSNP
rs112746963 1288 dbSNP
rs1382061779 1299 dbSNP
rs984345598 1305 dbSNP
rs1452603112 1313 dbSNP
rs1246375285 1322 dbSNP
rs1222497543 1323 dbSNP
rs529592730 1333 dbSNP
rs1338119493 1335 dbSNP
rs1216344883 1345 dbSNP
rs1355100876 1346 dbSNP
rs549732230 1355 dbSNP
rs1259684643 1357 dbSNP
rs148816706 1368 dbSNP
rs976832742 1376 dbSNP
rs1345140660 1384 dbSNP
rs1204976722 1385 dbSNP
rs922663118 1386 dbSNP
rs569578800 1388 dbSNP
rs182466044 1393 dbSNP
rs1297397959 1395 dbSNP
rs1420059482 1406 dbSNP
rs1362400002 1408 dbSNP
rs187914497 1421 dbSNP
rs1412836162 1422 dbSNP
rs923806660 1424 dbSNP
rs1424470964 1432 dbSNP
rs1191828040 1437 dbSNP
rs530678198 1444 dbSNP
rs936539848 1445 dbSNP
rs1261271580 1450 dbSNP
rs1488795693 1451 dbSNP
rs1252399278 1455 dbSNP
rs557855532 1462 dbSNP
rs983811551 1468 dbSNP
rs535514953 1471 dbSNP
rs192389350 1476 dbSNP
rs548796099 1479 dbSNP
rs1220422535 1481 dbSNP
rs1337095796 1488 dbSNP
rs1277124390 1497 dbSNP
rs894788402 1502 dbSNP
rs1012340457 1512 dbSNP
rs553938555 1514 dbSNP
rs1046093582 1520 dbSNP
rs906257764 1532 dbSNP
rs764940544 1539 dbSNP
rs142709935 1563 dbSNP
rs919455697 1564 dbSNP
rs184897260 1578 dbSNP
rs373561304 1590 dbSNP
rs988001995 1591 dbSNP
rs576135938 1596 dbSNP
rs1180466766 1597 dbSNP
rs1483247959 1599 dbSNP
rs1005734713 1605 dbSNP
rs1018954243 1611 dbSNP
rs1435523643 1611 dbSNP
rs1257034126 1614 dbSNP
rs1178589258 1619 dbSNP
rs1218796555 1619 dbSNP
rs1374489322 1623 dbSNP
rs765694965 1637 dbSNP
rs1404194718 1650 dbSNP
rs1319537186 1667 dbSNP
rs1291275810 1674 dbSNP
rs1227503418 1675 dbSNP
rs545110070 1680 dbSNP
rs977138525 1695 dbSNP
rs1450337243 1706 dbSNP
rs1029700910 1710 dbSNP
rs1299141179 1711 dbSNP
rs1399057639 1722 dbSNP
rs1426044779 1724 dbSNP
rs943417249 1726 dbSNP
rs1163179507 1732 dbSNP
rs1043054462 1748 dbSNP
rs1415193574 1750 dbSNP
rs904502184 1751 dbSNP
rs564940330 1757 dbSNP
rs934605690 1759 dbSNP
rs1052945728 1763 dbSNP
rs1306954892 1764 dbSNP
rs1237093227 1785 dbSNP
rs895677112 1786 dbSNP
rs977512142 1788 dbSNP
rs1458841495 1789 dbSNP
rs1014079920 1795 dbSNP
rs758384072 1797 dbSNP
rs3736850 1810 dbSNP
rs936510107 1812 dbSNP
rs989368805 1814 dbSNP
rs905615333 1815 dbSNP
rs1305441537 1816 dbSNP
rs1054611 1817 dbSNP
rs151006399 1818 dbSNP
rs1308703967 1820 dbSNP
rs1447569944 1821 dbSNP
rs746557774 1824 dbSNP
rs1198849090 1825 dbSNP
rs961019648 1828 dbSNP
rs906206112 1835 dbSNP
rs529552152 1842 dbSNP
rs1350772106 1844 dbSNP
rs1167327169 1855 dbSNP
rs993775488 1860 dbSNP
rs1380188461 1861 dbSNP
rs141041901 1863 dbSNP
rs1194970506 1865 dbSNP
rs547424283 1875 dbSNP
rs1190209441 1877 dbSNP
rs1488693169 1879 dbSNP
rs113430551 1887 dbSNP
rs1267055039 1893 dbSNP
rs1214174621 1894 dbSNP
rs1352949659 1895 dbSNP
rs1490802469 1903 dbSNP
rs1005659641 1909 dbSNP
rs1337544169 1915 dbSNP
rs567657299 1916 dbSNP
rs144777435 1918 dbSNP
rs1368563480 1919 dbSNP
rs187604898 1926 dbSNP
rs1030043832 1928 dbSNP
rs964835528 1937 dbSNP
rs773772117 1943 dbSNP
rs375796905 1948 dbSNP
rs1159740170 1951 dbSNP
rs1420996972 1956 dbSNP
rs1375375340 1962 dbSNP
rs561798752 1963 dbSNP
rs1297907289 1965 dbSNP
rs925977627 1971 dbSNP
rs1191299908 1972 dbSNP
rs934659027 1975 dbSNP
rs1263817535 1991 dbSNP
rs1487815966 1991 dbSNP
rs192085476 1995 dbSNP
rs1052999045 1998 dbSNP
rs866285478 2000 dbSNP
rs1033108427 2013 dbSNP
rs1232576358 2014 dbSNP
rs1313047590 2014 dbSNP
rs917181059 2015 dbSNP
rs949967296 2018 dbSNP
rs547268184 2019 dbSNP
rs957471392 2030 dbSNP
rs1044255309 2040 dbSNP
rs1236577647 2046 dbSNP
rs1300787665 2048 dbSNP
rs567503179 2055 dbSNP
rs184935255 2061 dbSNP
rs1038108092 2063 dbSNP
rs1214595173 2067 dbSNP
rs1171529241 2074 dbSNP
rs766397647 2079 dbSNP
rs947930356 2080 dbSNP
rs1305332481 2083 dbSNP
rs749647239 2088 dbSNP
rs1195563083 2089 dbSNP
rs1424147162 2089 dbSNP
rs753713169 2097 dbSNP
rs993827567 2098 dbSNP
rs982052528 2104 dbSNP
rs556532472 2106 dbSNP
rs1483598219 2112 dbSNP
rs1029711164 2113 dbSNP
rs929656780 2115 dbSNP
rs189458802 2122 dbSNP
rs1279308204 2123 dbSNP
rs1230031110 2126 dbSNP
rs1009533072 2127 dbSNP
rs1334030006 2130 dbSNP
rs1490216806 2134 dbSNP
rs1407577932 2136 dbSNP
rs1017798527 2142 dbSNP
rs749677154 2152 dbSNP
rs1464839025 2170 dbSNP
rs1400530219 2171 dbSNP
rs1172613553 2172 dbSNP
rs771603988 2176 dbSNP
rs978853548 2179 dbSNP
rs1188091985 2180 dbSNP
rs1046742266 2189 dbSNP
rs1245107855 2202 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 387837.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000396502.1 | 3UTR | AUAAAUUGCACUUUAGGGAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
Click to see details
118 hsa-miR-3160-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT066658 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT075318 SF3B3 splicing factor 3b subunit 3 2 4
MIRT077083 EIF1 eukaryotic translation initiation factor 1 2 2
MIRT100381 HSPA1B heat shock protein family A (Hsp70) member 1B 2 6
MIRT135259 TMBIM6 transmembrane BAX inhibitor motif containing 6 2 4
MIRT184913 ZNF268 zinc finger protein 268 2 2
MIRT218862 CDKN1A cyclin dependent kinase inhibitor 1A 2 2
MIRT446580 FPR2 formyl peptide receptor 2 2 2
MIRT448834 FGD4 FYVE, RhoGEF and PH domain containing 4 2 2
MIRT449455 RNF13 ring finger protein 13 2 2
MIRT452284 CARD8 caspase recruitment domain family member 8 2 2
MIRT452628 FAM162A family with sequence similarity 162 member A 2 2
MIRT453454 GLG1 golgi glycoprotein 1 2 2
MIRT454188 AP1S3 adaptor related protein complex 1 sigma 3 subunit 2 6
MIRT454434 GTF2F1 general transcription factor IIF subunit 1 2 2
MIRT454575 NT5DC3 5'-nucleotidase domain containing 3 2 2
MIRT455555 TRAF1 TNF receptor associated factor 1 2 6
MIRT455841 MPL MPL proto-oncogene, thrombopoietin receptor 2 6
MIRT455969 BCAS4 breast carcinoma amplified sequence 4 2 4
MIRT456805 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT457320 DUSP19 dual specificity phosphatase 19 2 2
MIRT457366 POFUT2 protein O-fucosyltransferase 2 2 2
MIRT457684 ZNF587 zinc finger protein 587 2 2
MIRT458158 LYRM4 LYR motif containing 4 2 6
MIRT458641 SGPP2 sphingosine-1-phosphate phosphatase 2 2 2
MIRT459134 FADS6 fatty acid desaturase 6 2 2
MIRT459153 NARF nuclear prelamin A recognition factor 2 4
MIRT460460 NOM1 nucleolar protein with MIF4G domain 1 2 4
MIRT460974 STK17B serine/threonine kinase 17b 2 2
MIRT461439 ACSBG1 acyl-CoA synthetase bubblegum family member 1 2 2
MIRT461507 NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 2 2
MIRT462490 GSR glutathione-disulfide reductase 2 2
MIRT462638 PHF5A PHD finger protein 5A 2 2
MIRT463279 ZFX zinc finger protein, X-linked 2 2
MIRT463360 ZFAND4 zinc finger AN1-type containing 4 2 2
MIRT465777 TMOD3 tropomodulin 3 2 2
MIRT466143 TMEM120B transmembrane protein 120B 2 2
MIRT468401 SETD3 SET domain containing 3 2 2
MIRT468998 RNPS1 RNA binding protein with serine rich domain 1 2 2
MIRT471574 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT472108 NME2 NME/NM23 nucleoside diphosphate kinase 2 2 2
MIRT472125 NME1-NME2 NME1-NME2 readthrough 2 2
MIRT473020 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT473083 MORN4 MORN repeat containing 4 2 2
MIRT475598 HMGB2 high mobility group box 2 2 4
MIRT475937 GXYLT2 glucoside xylosyltransferase 2 2 8
MIRT476117 GPR157 G protein-coupled receptor 157 2 2
MIRT476406 GDE1 glycerophosphodiester phosphodiesterase 1 2 2
MIRT478003 DNAL1 dynein axonemal light chain 1 2 2
MIRT487969 IQSEC2 IQ motif and Sec7 domain 2 2 2
MIRT489418 TUBB2A tubulin beta 2A class IIa 2 2
MIRT491522 IL10RA interleukin 10 receptor subunit alpha 2 2
MIRT492673 PLEC plectin 2 2
MIRT493545 ICOSLG inducible T-cell costimulator ligand 2 2
MIRT513085 USP9X ubiquitin specific peptidase 9, X-linked 2 2
MIRT514009 CECR2 CECR2, histone acetyl-lysine reader 2 4
MIRT516683 ZNF860 zinc finger protein 860 2 2
MIRT518392 ZNF250 zinc finger protein 250 2 2
MIRT522683 LUZP1 leucine zipper protein 1 2 6
MIRT524488 CEP97 centrosomal protein 97 2 2
MIRT527457 CLEC12B C-type lectin domain family 12 member B 2 2
MIRT527705 IL17REL interleukin 17 receptor E like 2 2
MIRT531647 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT532381 UMPS uridine monophosphate synthetase 2 2
MIRT532588 MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 2 2
MIRT533555 TPM4 tropomyosin 4 2 2
MIRT548371 ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 2 4
MIRT550250 PVR poliovirus receptor 2 2
MIRT552555 ZFP36L2 ZFP36 ring finger protein like 2 2 4
MIRT554113 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT554131 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT561344 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT561638 RUNX3 runt related transcription factor 3 2 2
MIRT566497 PBX2P1 PBX homeobox 2 pseudogene 1 2 2
MIRT570583 OTUD7B OTU deubiquitinase 7B 2 2
MIRT572731 MCTS1 MCTS1, re-initiation and release factor 2 2
MIRT574041 PEX26 peroxisomal biogenesis factor 26 2 2
MIRT575231 Fut1 fucosyltransferase 1 2 2
MIRT606811 BICD2 BICD cargo adaptor 2 2 2
MIRT621016 CLSTN3 calsyntenin 3 2 2
MIRT637852 PDCL3 phosducin like 3 2 2
MIRT640477 ZNF557 zinc finger protein 557 2 2
MIRT642827 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT643887 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2 2
MIRT664874 PCNXL2 pecanex homolog 2 2 2
MIRT680528 PRIM2 DNA primase subunit 2 2 2
MIRT680648 KIAA1456 KIAA1456 2 2
MIRT680807 ZNF578 zinc finger protein 578 2 2
MIRT680921 STX2 syntaxin 2 2 2
MIRT681112 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT681147 INTS7 integrator complex subunit 7 2 2
MIRT681966 TFCP2 transcription factor CP2 2 2
MIRT684316 GTF3C4 general transcription factor IIIC subunit 4 2 2
MIRT684906 GSG2 histone H3 associated protein kinase 2 2
MIRT685499 MED16 mediator complex subunit 16 2 2
MIRT685929 MOCS3 molybdenum cofactor synthesis 3 2 2
MIRT686875 SLC25A32 solute carrier family 25 member 32 2 2
MIRT688204 FNIP1 folliculin interacting protein 1 2 2
MIRT688791 CCNB1 cyclin B1 2 2
MIRT689227 RPS19 ribosomal protein S19 2 2
MIRT690470 ZNF33A zinc finger protein 33A 2 2
MIRT691982 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT694006 PPIL4 peptidylprolyl isomerase like 4 2 2
MIRT694529 TRIM72 tripartite motif containing 72 2 2
MIRT695420 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2 2
MIRT695784 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT697799 UBXN2A UBX domain protein 2A 2 2
MIRT698275 TMEM2 transmembrane protein 2 2 2
MIRT698317 TMEM136 transmembrane protein 136 2 2
MIRT699971 RREB1 ras responsive element binding protein 1 2 2
MIRT700717 PNO1 partner of NOB1 homolog 2 2
MIRT701721 MTMR12 myotubularin related protein 12 2 2
MIRT701879 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT702959 HIF1A hypoxia inducible factor 1 alpha subunit 2 2
MIRT706178 ZNF716 zinc finger protein 716 2 2
MIRT706463 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT718154 TTC33 tetratricopeptide repeat domain 33 2 2
MIRT718711 ANKRD18A ankyrin repeat domain 18A 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-3160-3p Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-3160-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-3160-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-3160-3p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-3160-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3160-3p Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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