miRTarBase - #MIRT527668


—
pre-miRNA Information
pre-miRNA hsa-mir-6715b   
Genomic Coordinates chr10: 112299612 - 112299688
Description Homo sapiens miR-6715b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6715b-3p
Sequence 46| CUCAAACCGGCUGUGCCUGUGG |67
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs761643095 7 dbSNP
rs768295556 8 dbSNP
rs182337914 9 dbSNP
rs1369684979 11 dbSNP
rs776704371 13 dbSNP
rs1039819520 15 dbSNP
rs771110697 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CIT   
Synonyms CITK, CRIK, MCPH17, STK21
Description citron rho-interacting serine/threonine kinase
Transcript NM_007174   
Expression
Putative miRNA Targets on CIT
3'UTR of CIT
(miRNA target sites are highlighted)		 
>CIT|NM_007174|3'UTR
   1 ATCTCAGCCAGAAAAACCAACTCCTCATCTTGATCTGCAGGAAAACACCAAACACACTATGGAACTCTGCTGATGGGGAC
  81 CCAAGCGCCCACGTGCTCAGCCACCCTCTGGCTCAGCGGGGCCCAGACCCACCTCGGCACGGACACCCCTGTCTCCAGGA
 161 GGGGCAGGTGGCTGAGGCTCTTCGGAGCTGTCAGCGCCCGGTGCCTGCCCTGGGCACCTCCCTGCAGTCATCTCTTTGCA
 241 CTTTGTTACTCTTTCAAAGCATTCACAAACTTTTGTACCTAGCTCTAGCCTGTACCAGTTAGTTCATCAAAGGAAACCAA
 321 CCGGGATGCTAACTACAACATGGTTAGAATCCTAATTAGCTACTTTAAGATCCTAGGATTGGTTGGTTTTTCTTTTTTTT
 401 TTCTCTTTGTTTCTTTCCTTTTTTTTTTTTTTTTTTTAAGACAACAGAATTCTTAATAGATTTGAATAGCGACGTATTTC
 481 CTGTTGTAGTCATTTTTAGCTCGACCACATCATCAGGTCTTTGCCACCGAGGCATAGTGTAGAACAGTCCCGGTCAGTTG
 561 GCCAACCTCCCGCAGCCAAGTAGGTTCATCCTTGTTCCTGTTCATTCTCATAGATGGCCCTGCTTTCCCCAGGGTGACAT
 641 CGTAGCCAAATGTTTACTGTTTTCATTGCCTTTTATGGCCTTGACGACTTCCCCTCCCACCAGCTGAGAATGTATGGAGG
 721 TCATCGGGGCCTCAGCTCGGAGGCAGTGACTTGGGGCCAAGGGACCTCGAGACGCTTTCCTTCCCCACCCCCCAGCGTCA
 801 TCTCCCCAGCCTGCTGTTCCCGCTTTCCATATAGCTTTGGCCAGGAAAGCATGCAATAGACTTGCTCGGAGCCCAGCACT
 881 CCTGGGTCTCGGGGTCGGGGAGGGGACGGGGGCACCCACTTCCTTGTCTGTGACGGCGTGTTGTTCCCCACTCTGGGATG
 961 GGGAAGAGGCCCGTCGGGAGTTCTGCATGGCAGTTCACTGCATGTGCTGCCCCCTTGGGTTGCTCTGCCAATGTATTAAT
1041 ACCATCCCATAGCTCCTGCCAAATCGAGACCCTCTGACGACTTGCCGACTAACTGGCCACCACAAGCTGCAGTCTGTAGC
1121 ACTGAACAAACAAAAAACAAAACGCTCAAGCCTTACGACCAGAGAAGGATTTCAGCAAACCACCACCTCCCACTCAGTGT
1201 CCCCTCCAAACTTCACACTTCCCTGCCTGCAGAGGATGACTCTGTTCACACCCAATCCAGCGCGGTTCTACCCCACGAAA
1281 CTGTGACTTTCCAAATGAGCCTTTCCCTAGGGCTAGACCTAAGACCAGGAAGTTTGAGAAAGCAGCCGCAGCTCAACTCT
1361 TCCAGCTCCGCCAGGGTTGGGAAGTCCTTAGGTGCAGTGCGGCTCCCACTGGGTCTGCGGACCCTCCTATTAGAGTACGA
1441 AATTCCTGGCAACTGGTACAGAACCAACCTAGAGGCTTTGCAGTTGGCAAGCTAACTCGCGGCCTTATTTCTGCCTTTAA
1521 TCTCCCACAAGGCATCTGTTGCTTTGGGTCCTCCACGACTCTTAGGCCCGCCTCAACAACCCAGGCACCTCCTAGGTAGG
1601 CTCAAAGGTAGACCCGTTTCCACCGCAGCAGGTGAACATGACCGTGTTTTCAACTGTGTCCACAGTTCAGATCCCTTTCC
1681 AGATTGCAACCTGGCCTGCATCCCAGCTCCTTCCTGCTCGTGTCTTAACCTAAGTGCTTTCTTGTTTGAAACGCCTACAA
1761 ACCTCCATGTGGTAGCTCCTTTGGCAAATGTCCTGCTGTGGCGTTTTATGTGTTGCTTGGAGTCTGTGGGGTCGTACTCC
1841 CTCCCCTCCCGTCCCCAGGGCAGATTTGATTGAATGTTTGCTGAAGTTTTGTCTCTTGGTCCACAGTATTTGGAAAGGTC
1921 ACTGAAAATGGGTCTTTCAGTCTTGGCATTTCATTTAGGATCTCCATGAGAAATGGGCTTCTTGAGCCCTGAAAATGTAT
2001 ATTGTGTGTCTCATCTGTGAACTGCTTTCTGCTATATAGAACTAGCTCAAAAGACTGTACATATTTACAAGAAACTTTAT
2081 ATTCGTAAAAAAAAAAAGAGGAAATTGAATTGGTTTCTACTTTTTTATTGTAAAAGGTGCATTTTTCAACACTTACTTTT
2161 GGTTTCAATGGTGGTAGTTGTGGACAGCCATCTTCACTGGAGGGTGGGGAGCTCCGTGTGACCACCAAGATGCCAGCAGG
2241 ATATACCGTAACACGAAATTGCTGTCAAAAGCTTATTAGCATCAATCAAGATTCTAGGTCTCCAAAAGTACAGGCTTTTT
2321 CTTCATTACCTTTTTTATTCAGAACGAGGAAGAGAACACAAGGAATGATTCAAGATCCACCTTGAGAGGAATGAACTTTG
2401 TTGTTGAACAATTAGTGAAATAAAGCAATGATCTAAACTAAT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggUGUCCGUGUCGGCCAAACUc 5'
            |||  :||  ::||||| | 
Target 5' caACACTTACTTTTGGTTTCAa 3'
 2147 - 2168 124.00 -9.32
2 
miRNA  3' gguguccGUGUCGGCCAAACUc 5'
                 || :|| | ||||| 
Target 5' ccgtcccCAGGGCAGATTTGAt 3'
 1849 - 1870 123.00 -13.00
3 
miRNA  3' ggugUCCGUGUCGGCCAAACUc 5'
              || | |||   |||||| 
Target 5' cctaAGAC-CAGGAAGTTTGAg 3'
 1318 - 1338 121.00 -12.00
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30470330 35 COSMIC
COSN31593263 37 COSMIC
COSN31505568 43 COSMIC
COSN30106082 72 COSMIC
COSN31525862 73 COSMIC
COSN26970789 76 COSMIC
COSN30645056 82 COSMIC
COSN17078459 86 COSMIC
COSN24386953 87 COSMIC
COSN30096655 121 COSMIC
COSN31526327 141 COSMIC
COSN24399500 165 COSMIC
COSN30536739 184 COSMIC
COSN31578018 196 COSMIC
COSN31532398 227 COSMIC
COSN30132998 232 COSMIC
COSN28743134 234 COSMIC
COSN31586977 234 COSMIC
COSN17258714 302 COSMIC
COSN29569621 315 COSMIC
COSN26660403 413 COSMIC
COSN20110205 419 COSMIC
COSN28821571 470 COSMIC
COSN31585554 686 COSMIC
COSN31607678 726 COSMIC
COSN30169424 738 COSMIC
COSN31597408 770 COSMIC
COSN31534215 772 COSMIC
COSN7313196 774 COSMIC
COSN29461596 797 COSMIC
COSN26679405 819 COSMIC
COSN26569488 824 COSMIC
COSN26586029 842 COSMIC
COSN31540751 915 COSMIC
COSN31537323 973 COSMIC
COSN30539242 1078 COSMIC
COSN31593698 1154 COSMIC
COSN31549274 1157 COSMIC
COSN25079048 1198 COSMIC
COSN31593834 1300 COSMIC
COSN28650891 1340 COSMIC
COSN31575128 1369 COSMIC
COSN31583944 1406 COSMIC
COSN25151512 1411 COSMIC
COSN25556314 1702 COSMIC
COSN24042183 1851 COSMIC
COSN21909084 1922 COSMIC
COSN31490252 1942 COSMIC
COSN31480402 1962 COSMIC
COSN31570415 2071 COSMIC
COSN31490857 2252 COSMIC
COSN31533955 2315 COSMIC
COSN1559821 2361 COSMIC
COSN30174391 2384 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1364311362 2 dbSNP
rs770371286 12 dbSNP
rs746526012 17 dbSNP
rs775064750 18 dbSNP
rs191889106 20 dbSNP
rs771682584 23 dbSNP
rs1195596820 26 dbSNP
rs745514606 30 dbSNP
rs1174721874 32 dbSNP
rs778614412 33 dbSNP
rs369043146 34 dbSNP
rs1376875167 35 dbSNP
rs1196427301 37 dbSNP
rs1429968147 38 dbSNP
rs905571444 39 dbSNP
rs749033181 42 dbSNP
rs777700944 45 dbSNP
rs1362928705 58 dbSNP
rs536415444 80 dbSNP
rs1300731256 84 dbSNP
rs374513595 86 dbSNP
rs761061902 87 dbSNP
rs774170239 92 dbSNP
rs567838142 93 dbSNP
rs1348295274 110 dbSNP
rs547836461 112 dbSNP
rs528100669 117 dbSNP
rs886386667 118 dbSNP
rs1489224986 119 dbSNP
rs1470100001 121 dbSNP
rs1035101791 123 dbSNP
rs565583351 129 dbSNP
rs770669686 132 dbSNP
rs1022563497 135 dbSNP
rs552125372 136 dbSNP
rs1474744242 137 dbSNP
rs1382761549 140 dbSNP
rs141113548 141 dbSNP
rs1161174136 151 dbSNP
rs1389418176 161 dbSNP
rs1184637528 162 dbSNP
rs1325119116 175 dbSNP
rs1333618406 179 dbSNP
rs548661142 180 dbSNP
rs563561560 183 dbSNP
rs1309693390 184 dbSNP
rs1467047988 189 dbSNP
rs565197913 192 dbSNP
rs1355820526 193 dbSNP
rs535221798 195 dbSNP
rs901602725 196 dbSNP
rs187084121 199 dbSNP
rs12425960 200 dbSNP
rs1308168503 209 dbSNP
rs1272452611 213 dbSNP
rs569495109 218 dbSNP
rs34347291 223 dbSNP
rs1240380059 238 dbSNP
rs1443120490 279 dbSNP
rs537350650 287 dbSNP
rs1337414341 288 dbSNP
rs748116784 296 dbSNP
rs907679796 301 dbSNP
rs989056873 308 dbSNP
rs984625054 312 dbSNP
rs1393946713 316 dbSNP
rs561376798 317 dbSNP
rs1453136839 320 dbSNP
rs1378862368 321 dbSNP
rs569819000 322 dbSNP
rs990860046 333 dbSNP
rs1311925117 336 dbSNP
rs1340986012 338 dbSNP
rs1247156483 341 dbSNP
rs960658847 343 dbSNP
rs1249664272 365 dbSNP
rs1317559147 367 dbSNP
rs1334285675 369 dbSNP
rs1199542026 380 dbSNP
rs1377108970 384 dbSNP
rs1460263614 385 dbSNP
rs1443846138 389 dbSNP
rs139790082 392 dbSNP
rs1426055921 397 dbSNP
rs928046259 398 dbSNP
rs980654890 402 dbSNP
rs1191785729 403 dbSNP
rs1477184010 403 dbSNP
rs921010164 403 dbSNP
rs1169211167 405 dbSNP
rs371624695 406 dbSNP
rs1387685714 407 dbSNP
rs1401935469 407 dbSNP
rs1302029236 409 dbSNP
rs1451437535 409 dbSNP
rs879109280 409 dbSNP
rs1397680103 413 dbSNP
rs371711572 413 dbSNP
rs200647679 417 dbSNP
rs1339966483 419 dbSNP
rs1444434153 419 dbSNP
rs369017284 419 dbSNP
rs1241624348 420 dbSNP
rs1179307406 434 dbSNP
rs1354110683 435 dbSNP
rs1426425076 436 dbSNP
rs10574499 438 dbSNP
rs1233047527 438 dbSNP
rs1256927844 438 dbSNP
rs1321657800 438 dbSNP
rs1425395695 438 dbSNP
rs1484420833 438 dbSNP
rs1487676167 438 dbSNP
rs746787416 438 dbSNP
rs749478842 438 dbSNP
rs796243587 438 dbSNP
rs796939551 438 dbSNP
rs199521589 440 dbSNP
rs1232487148 441 dbSNP
rs572499652 444 dbSNP
rs969847810 458 dbSNP
rs1378020569 459 dbSNP
rs1024462093 461 dbSNP
rs1361623283 466 dbSNP
rs770242208 469 dbSNP
rs1246542936 470 dbSNP
rs1358477495 473 dbSNP
rs1400754894 493 dbSNP
rs1343919763 503 dbSNP
rs565163538 514 dbSNP
rs1310383041 517 dbSNP
rs1225250255 528 dbSNP
rs780927603 529 dbSNP
rs1286008254 531 dbSNP
rs545371423 535 dbSNP
rs775360619 537 dbSNP
rs754785136 538 dbSNP
rs954479344 551 dbSNP
rs994715401 552 dbSNP
rs1028534686 553 dbSNP
rs1434759188 557 dbSNP
rs1156598256 558 dbSNP
rs1430385133 564 dbSNP
rs751312201 571 dbSNP
rs1424652042 572 dbSNP
rs1420201230 575 dbSNP
rs576681623 584 dbSNP
rs1161785404 594 dbSNP
rs1420027792 633 dbSNP
rs549601850 638 dbSNP
rs1007791000 639 dbSNP
rs780292863 640 dbSNP
rs1004615329 641 dbSNP
rs1490862960 642 dbSNP
rs1242987132 644 dbSNP
rs1290155819 648 dbSNP
rs889899290 651 dbSNP
rs886177418 652 dbSNP
rs1221821864 655 dbSNP
rs1490184274 656 dbSNP
rs556412697 660 dbSNP
rs1051611249 663 dbSNP
rs1049401990 664 dbSNP
rs1263570640 665 dbSNP
rs930491796 675 dbSNP
rs916488789 679 dbSNP
rs1055018150 685 dbSNP
rs939351064 692 dbSNP
rs1180450845 697 dbSNP
rs372557090 700 dbSNP
rs1404903751 701 dbSNP
rs1305889700 714 dbSNP
rs1165550791 715 dbSNP
rs1226117018 717 dbSNP
rs1346993187 725 dbSNP
rs758593205 726 dbSNP
rs936258258 731 dbSNP
rs926165681 735 dbSNP
rs980325559 737 dbSNP
rs536452496 739 dbSNP
rs1403766191 751 dbSNP
rs917039653 758 dbSNP
rs978073019 759 dbSNP
rs967227833 762 dbSNP
rs992994782 765 dbSNP
rs1291098539 766 dbSNP
rs573857222 768 dbSNP
rs915324144 769 dbSNP
rs950430743 770 dbSNP
rs990056118 774 dbSNP
rs1157217109 775 dbSNP
rs1481573182 781 dbSNP
rs1476853503 783 dbSNP
rs1170252398 785 dbSNP
rs879543792 788 dbSNP
rs1401218941 789 dbSNP
rs1025953592 791 dbSNP
rs181970708 792 dbSNP
rs1198835272 793 dbSNP
rs1449445380 794 dbSNP
rs534468395 796 dbSNP
rs10774512 797 dbSNP
rs1216183127 808 dbSNP
rs1277257569 813 dbSNP
rs754380830 817 dbSNP
rs1318144949 821 dbSNP
rs1206780809 822 dbSNP
rs764648673 829 dbSNP
rs1276201886 844 dbSNP
rs1441589248 852 dbSNP
rs1210754082 853 dbSNP
rs551899364 867 dbSNP
rs770518295 868 dbSNP
rs1193035711 877 dbSNP
rs886227562 881 dbSNP
rs998275054 885 dbSNP
rs60243987 890 dbSNP
rs569968173 891 dbSNP
rs894953951 892 dbSNP
rs1433978176 896 dbSNP
rs1328811346 897 dbSNP
rs1359185792 897 dbSNP
rs1397663064 901 dbSNP
rs1054946380 907 dbSNP
rs939277744 908 dbSNP
rs1298386582 917 dbSNP
rs935975484 919 dbSNP
rs550059090 923 dbSNP
rs1045040537 934 dbSNP
rs775965889 935 dbSNP
rs1042449720 937 dbSNP
rs770757558 938 dbSNP
rs1280733164 946 dbSNP
rs915317911 949 dbSNP
rs544968662 950 dbSNP
rs1216036889 951 dbSNP
rs762656991 961 dbSNP
rs921458598 968 dbSNP
rs976877801 972 dbSNP
rs373993254 973 dbSNP
rs772668842 975 dbSNP
rs1246281490 976 dbSNP
rs1478601411 984 dbSNP
rs1174669392 987 dbSNP
rs1015796174 988 dbSNP
rs1195253374 996 dbSNP
rs1419590866 1002 dbSNP
rs1429120547 1004 dbSNP
rs1260923112 1006 dbSNP
rs1360630637 1012 dbSNP
rs1401879425 1014 dbSNP
rs1321180060 1020 dbSNP
rs1330142772 1022 dbSNP
rs918992114 1024 dbSNP
rs973065379 1031 dbSNP
rs963009804 1032 dbSNP
rs1239365749 1042 dbSNP
rs1286580163 1042 dbSNP
rs1017553877 1065 dbSNP
rs796349233 1066 dbSNP
rs1243414181 1071 dbSNP
rs530006545 1078 dbSNP
rs1201511850 1079 dbSNP
rs1009376707 1086 dbSNP
rs1439415392 1089 dbSNP
rs1252617251 1099 dbSNP
rs891915242 1099 dbSNP
rs950380712 1102 dbSNP
rs1227510160 1104 dbSNP
rs1470916076 1107 dbSNP
rs561113630 1113 dbSNP
rs994619967 1119 dbSNP
rs747557585 1125 dbSNP
rs1477758469 1130 dbSNP
rs1327445214 1132 dbSNP
rs1000237324 1133 dbSNP
rs528483836 1143 dbSNP
rs1309978881 1144 dbSNP
rs1003373034 1147 dbSNP
rs906449515 1151 dbSNP
rs781217047 1156 dbSNP
rs945381802 1157 dbSNP
rs1383938456 1159 dbSNP
rs768546322 1161 dbSNP
rs1457605766 1162 dbSNP
rs1199658831 1168 dbSNP
rs1336327500 1176 dbSNP
rs1057257819 1177 dbSNP
rs929456956 1180 dbSNP
rs547548592 1181 dbSNP
rs919045811 1189 dbSNP
rs973117624 1191 dbSNP
rs1367405231 1211 dbSNP
rs1054178413 1214 dbSNP
rs746851863 1215 dbSNP
rs34460265 1224 dbSNP
rs1398889500 1225 dbSNP
rs1421013159 1227 dbSNP
rs1464957228 1231 dbSNP
rs941757471 1240 dbSNP
rs1461527565 1255 dbSNP
rs1394255821 1260 dbSNP
rs932781706 1261 dbSNP
rs374008004 1262 dbSNP
rs1166598424 1263 dbSNP
rs921340449 1264 dbSNP
rs1317507560 1265 dbSNP
rs1219686824 1268 dbSNP
rs527816647 1271 dbSNP
rs976930074 1276 dbSNP
rs944172909 1277 dbSNP
rs908808949 1278 dbSNP
rs1257391909 1279 dbSNP
rs1243469357 1282 dbSNP
rs1182740139 1286 dbSNP
rs1189426872 1291 dbSNP
rs1260650011 1293 dbSNP
rs983026757 1296 dbSNP
rs1170904965 1299 dbSNP
rs953056688 1301 dbSNP
rs779807909 1302 dbSNP
rs1171934043 1309 dbSNP
rs1030235573 1319 dbSNP
rs1195919013 1326 dbSNP
rs1479995981 1332 dbSNP
rs3742046 1340 dbSNP
rs565080437 1347 dbSNP
rs959146435 1347 dbSNP
rs1360632757 1348 dbSNP
rs545096210 1349 dbSNP
rs779206878 1369 dbSNP
rs1257154570 1370 dbSNP
rs1350648340 1377 dbSNP
rs906335459 1384 dbSNP
rs1021310888 1391 dbSNP
rs1487650168 1392 dbSNP
rs1329731465 1397 dbSNP
rs140757578 1400 dbSNP
rs1009510763 1401 dbSNP
rs1306125187 1406 dbSNP
rs750662144 1408 dbSNP
rs893701596 1418 dbSNP
rs1436471025 1419 dbSNP
rs1385784225 1422 dbSNP
rs1339921854 1427 dbSNP
rs748430521 1428 dbSNP
rs1359994794 1432 dbSNP
rs1420312390 1433 dbSNP
rs778943227 1438 dbSNP
rs1386609806 1439 dbSNP
rs1162471305 1451 dbSNP
rs278123 1459 dbSNP
rs753822364 1464 dbSNP
rs542956602 1467 dbSNP
rs1285864513 1468 dbSNP
rs1352343457 1469 dbSNP
rs1182029594 1471 dbSNP
rs1041075785 1478 dbSNP
rs189788414 1481 dbSNP
rs1023399184 1483 dbSNP
rs112436800 1487 dbSNP
rs534365979 1489 dbSNP
rs908737229 1490 dbSNP
rs1490675258 1496 dbSNP
rs146454606 1498 dbSNP
rs116432235 1500 dbSNP
rs898003861 1501 dbSNP
rs1280364740 1506 dbSNP
rs538263849 1511 dbSNP
rs1457619026 1513 dbSNP
rs569703361 1514 dbSNP
rs1397164517 1520 dbSNP
rs920167374 1522 dbSNP
rs1309267653 1534 dbSNP
rs1378282322 1541 dbSNP
rs1223904415 1546 dbSNP
rs1308483007 1548 dbSNP
rs1319362730 1556 dbSNP
rs1050545433 1565 dbSNP
rs1348848136 1570 dbSNP
rs1273351312 1573 dbSNP
rs973095913 1576 dbSNP
rs1285351590 1584 dbSNP
rs1405602416 1595 dbSNP
rs932983601 1598 dbSNP
rs1480898443 1599 dbSNP
rs1366164910 1608 dbSNP
rs1178835521 1614 dbSNP
rs1411743436 1615 dbSNP
rs923224326 1621 dbSNP
rs958992824 1624 dbSNP
rs1420291146 1625 dbSNP
rs1464448702 1630 dbSNP
rs1331074718 1638 dbSNP
rs1401715394 1643 dbSNP
rs112761399 1644 dbSNP
rs1301554541 1651 dbSNP
rs925126139 1690 dbSNP
rs1456429364 1700 dbSNP
rs979258642 1703 dbSNP
rs536597274 1709 dbSNP
rs1216611193 1713 dbSNP
rs1023029642 1719 dbSNP
rs35654900 1719 dbSNP
rs981832871 1720 dbSNP
rs1206549499 1731 dbSNP
rs1235602885 1748 dbSNP
rs563855886 1752 dbSNP
rs970448235 1760 dbSNP
rs35087900 1767 dbSNP
rs1188732969 1773 dbSNP
rs1259939491 1776 dbSNP
rs1013370828 1783 dbSNP
rs1170192793 1796 dbSNP
rs1420697468 1799 dbSNP
rs960057735 1802 dbSNP
rs148847848 1803 dbSNP
rs1020816072 1808 dbSNP
rs185421723 1809 dbSNP
rs1413686961 1823 dbSNP
rs1285467043 1826 dbSNP
rs1312919783 1828 dbSNP
rs1204916824 1829 dbSNP
rs1397771527 1833 dbSNP
rs1277111591 1839 dbSNP
rs565255463 1846 dbSNP
rs60839947 1850 dbSNP
rs1311514184 1851 dbSNP
rs145582303 1851 dbSNP
rs1037848636 1853 dbSNP
rs1801578 1857 dbSNP
rs1211740481 1860 dbSNP
rs1032637116 1863 dbSNP
rs767993994 1867 dbSNP
rs1193233422 1876 dbSNP
rs1434135560 1882 dbSNP
rs544052466 1885 dbSNP
rs562568483 1889 dbSNP
rs1189818499 1904 dbSNP
rs1425130575 1905 dbSNP
rs542606631 1930 dbSNP
rs759757290 1935 dbSNP
rs772932735 1948 dbSNP
rs1318800114 1959 dbSNP
rs1376753658 1984 dbSNP
rs747162259 1989 dbSNP
rs578161579 1994 dbSNP
rs764751317 1999 dbSNP
rs1050181849 2007 dbSNP
rs933015684 2010 dbSNP
rs879301510 2022 dbSNP
rs1234960945 2024 dbSNP
rs755428561 2029 dbSNP
rs922941109 2034 dbSNP
rs1178095571 2036 dbSNP
rs1052076257 2037 dbSNP
rs1215968309 2045 dbSNP
rs887182574 2052 dbSNP
rs1448925029 2055 dbSNP
rs1047263958 2060 dbSNP
rs931430667 2061 dbSNP
rs925176772 2063 dbSNP
rs979698400 2065 dbSNP
rs969245291 2066 dbSNP
rs916013277 2067 dbSNP
rs991595040 2069 dbSNP
rs920198041 2071 dbSNP
rs1170286395 2079 dbSNP
rs1157462214 2084 dbSNP
rs879177268 2085 dbSNP
rs1243172827 2096 dbSNP
rs1035673682 2098 dbSNP
rs1441278036 2098 dbSNP
rs199571119 2098 dbSNP
rs370292262 2098 dbSNP
rs960073116 2098 dbSNP
rs1238469660 2100 dbSNP
rs1327909786 2100 dbSNP
rs993432960 2100 dbSNP
rs962300780 2101 dbSNP
rs1056420596 2109 dbSNP
rs1245232392 2110 dbSNP
rs1345232127 2113 dbSNP
rs937677696 2127 dbSNP
rs1204472789 2134 dbSNP
rs1469239819 2149 dbSNP
rs749950778 2156 dbSNP
rs1236940959 2159 dbSNP
rs1457689060 2165 dbSNP
rs926298891 2168 dbSNP
rs529554918 2176 dbSNP
rs970500424 2189 dbSNP
rs1161100575 2190 dbSNP
rs1341435844 2191 dbSNP
rs560793850 2196 dbSNP
rs987997524 2200 dbSNP
rs1434132965 2201 dbSNP
rs1461810837 2206 dbSNP
rs1362685057 2208 dbSNP
rs116873393 2215 dbSNP
rs997293293 2216 dbSNP
rs1452995998 2233 dbSNP
rs149713019 2247 dbSNP
rs112117334 2248 dbSNP
rs543668784 2250 dbSNP
rs963914473 2251 dbSNP
rs934965303 2252 dbSNP
rs1420872106 2254 dbSNP
rs903809510 2255 dbSNP
rs1019604904 2256 dbSNP
rs545117394 2257 dbSNP
rs576202938 2264 dbSNP
rs1256599902 2271 dbSNP
rs1339087583 2271 dbSNP
rs1196900289 2284 dbSNP
rs947928652 2285 dbSNP
rs887199820 2294 dbSNP
rs140629821 2297 dbSNP
rs938784507 2300 dbSNP
rs928712065 2305 dbSNP
rs972064224 2308 dbSNP
rs1461234271 2315 dbSNP
rs995701677 2316 dbSNP
rs1412892320 2321 dbSNP
rs1312321163 2337 dbSNP
rs776094992 2345 dbSNP
rs768634097 2348 dbSNP
rs937607106 2352 dbSNP
rs1206774759 2369 dbSNP
rs573040453 2373 dbSNP
rs1168187217 2378 dbSNP
rs1416882724 2381 dbSNP
rs1438428356 2389 dbSNP
rs536213631 2392 dbSNP
rs1227504094 2396 dbSNP
rs1228611876 2411 dbSNP
rs907446444 2423 dbSNP
rs1316983718 2424 dbSNP
rs181269478 2441 dbSNP
rs1343452749 2442 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 11113.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gguguccgugucggcCAAACUc 5'
                         |||||| 
Target 5' -cuaagugcuuucuuGUUUGA- 3'
 		1 - 20
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000392521.2 | 3UTR | CUAAGUGCUUUCUUGUUUGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
75 hsa-miR-6715b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080245 SMAD4 SMAD family member 4 2 2
MIRT142553 TNRC6A trinucleotide repeat containing 6A 2 4
MIRT384667 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT446660 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT463754 YTHDC1 YTH domain containing 1 2 2
MIRT476873 FEM1B fem-1 homolog B 2 2
MIRT478429 DAZAP2 DAZ associated protein 2 2 2
MIRT495237 SPRY3 sprouty RTK signaling antagonist 3 2 4
MIRT495945 ANKRD52 ankyrin repeat domain 52 2 2
MIRT497116 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT497344 RPP25L ribonuclease P/MRP subunit p25 like 2 2
MIRT498133 KLHL3 kelch like family member 3 2 2
MIRT502306 GNA13 G protein subunit alpha 13 2 2
MIRT510854 RAN RAN, member RAS oncogene family 2 8
MIRT513323 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 6
MIRT523995 DTX4 deltex E3 ubiquitin ligase 4 2 4
MIRT525837 FAR2 fatty acyl-CoA reductase 2 2 2
MIRT527506 MYD88 myeloid differentiation primary response 88 2 2
MIRT527668 CIT citron rho-interacting serine/threonine kinase 2 2
MIRT527996 NDNF neuron derived neurotrophic factor 2 2
MIRT528052 MRS2 MRS2, magnesium transporter 2 2
MIRT528257 GPRIN2 G protein regulated inducer of neurite outgrowth 2 2 2
MIRT529401 ICK intestinal cell kinase 2 2
MIRT529558 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT530323 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT532230 KLF2 Kruppel like factor 2 2 2
MIRT534220 SLC35G1 solute carrier family 35 member G1 2 2
MIRT536195 MAML2 mastermind like transcriptional coactivator 2 2 2
MIRT538093 DEPDC1 DEP domain containing 1 2 2
MIRT543159 GTF2A1 general transcription factor IIA subunit 1 2 2
MIRT545840 ZNF264 zinc finger protein 264 2 4
MIRT546401 SRP9 signal recognition particle 9 2 2
MIRT550643 SLC39A7 solute carrier family 39 member 7 2 2
MIRT558648 CNKSR3 CNKSR family member 3 2 2
MIRT562208 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT562886 NACA2 nascent polypeptide associated complex alpha subunit 2 2 2
MIRT566786 MKL2 MKL1/myocardin like 2 2 2
MIRT567508 FOXC1 forkhead box C1 2 2
MIRT570235 CPNE5 copine 5 2 2
MIRT576823 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT610704 GPX6 glutathione peroxidase 6 2 2
MIRT611141 CRISP1 cysteine rich secretory protein 1 2 4
MIRT618100 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT619086 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT619716 FCF1 FCF1, rRNA-processing protein 2 2
MIRT620953 POLR2D RNA polymerase II subunit D 2 2
MIRT624645 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT624655 ARMC10 armadillo repeat containing 10 2 2
MIRT630778 KLHL42 kelch like family member 42 2 4
MIRT635596 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT637122 MKX mohawk homeobox 2 2
MIRT645527 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT647249 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT651508 WNT9A Wnt family member 9A 2 2
MIRT658721 ELK4 ELK4, ETS transcription factor 2 2
MIRT658804 EFNA5 ephrin A5 2 2
MIRT659319 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT664605 UGT3A1 UDP glycosyltransferase family 3 member A1 2 2
MIRT666047 STON2 stonin 2 2 2
MIRT672228 PDE7B phosphodiesterase 7B 2 2
MIRT683243 WFDC6 WAP four-disulfide core domain 6 2 2
MIRT686565 TPM3 tropomyosin 3 2 2
MIRT697560 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT699294 SLC5A3 solute carrier family 5 member 3 2 2
MIRT707134 TRA2B transformer 2 beta homolog 2 2
MIRT712255 PTPRN2 protein tyrosine phosphatase, receptor type N2 2 2
MIRT713896 IGF2R insulin like growth factor 2 receptor 2 2
MIRT716186 UBN2 ubinuclein 2 2 2
MIRT716525 KSR2 kinase suppressor of ras 2 2 2
MIRT716968 CNOT6 CCR4-NOT transcription complex subunit 6 2 2
MIRT717154 LRRC3C leucine rich repeat containing 3C 2 2
MIRT718669 LSM10 LSM10, U7 small nuclear RNA associated 2 2
MIRT722100 PTBP3 polypyrimidine tract binding protein 3 2 2
MIRT723569 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT724703 CRAMP1L cramped chromatin regulator homolog 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6715b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-6715b-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

Error report submission