pre-miRNA Information
pre-miRNA hsa-mir-4524a   
Genomic Coordinates chr17: 69099564 - 69099632
Description Homo sapiens miR-4524a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524a-5p
Sequence 6| AUAGCAGCAUGAACCUGUCUCA |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1322445998 8 dbSNP
rs1350790266 13 dbSNP
rs1263495678 21 dbSNP
Putative Targets

Gene Information
Gene Symbol TMEM44   
Synonyms -
Description transmembrane protein 44
Transcript NM_001166306   
Other Transcripts NM_001166305 , NM_001011655 , NM_138399   
Expression
Putative miRNA Targets on TMEM44
3'UTR of TMEM44
(miRNA target sites are highlighted)
>TMEM44|NM_001166306|3'UTR
   1 ACCTCGAAGGCAGCAAAGAAAATGTGGAGCTACTGGGATCCCAGGTGCACCAGGACTCTGTGAGGACAGCACACCTGAGT
  81 GATGATGATTAACACCTTCTGGAGCCAGCTCATCAGCTCAGAGCCCAGGGTCAGGAGTTCGTTCAGTAACGCAGCGGGAA
 161 TCAATCTGCACTGACACCGCGGCAGGAACTGAAGCTGCCCTGGCAAGTGAGGAACCAGGAGCCGTCACTGAGTGTGGCTG
 241 GGCTACATCATAGCTCATCACGGAGCTACGACTTTGGGTACTGCGGACAGACCTGGATAGGCCCAGCATTCGTTCTGAAG
 321 ATCACAGTTCACAGAAGCTTTTGCTTCGTAAAGATAATCCAAAGGATCTCAGACCCGCTCTTCCTTTTCCCTTCATTCCC
 401 TTGAGAGTCAGCCATGAACGGAATACCTGCTAGGTTCCAGGAATGAGCTCACCTAACAGATAGCAAATGTGTCTGGTTAG
 481 ATCTCAGCAGAGCCCATTCTGCAAGACCTGGCTGAGCCAGATGAGAGGGTGGGCCCTGTGCTGGGGGGCCTTGGGTCACA
 561 CACAGGAACCGAGACCTGGCTTCCACCCCCCAGTCACCCACTTGGGTTATCTGCTGGAAGTTATCGATAGGACTGTGTGG
 641 CCAACCAAGTGCTTGTGAGATCACTGACACTGCAAAAACAAAGCAAACTGCTCCGGGTACCAGGACTTCCTCCAACCTGG
 721 CAAGGGTGTGCGCTGAGGCGGGGCTTGCAGGTGAGGGGGCTGTATGCTTCAGGAACTAACTAAATGCATGCAGAAGGTAA
 801 GAGGCATGATGGGAGGTGTTCAAGCACAGCAATCCCATTTGGGAGTTATTTTGATACTGCGATGAGTAAGGGTAAGGGCG
 881 CATGGAATGGGGCTAAGGTGGGAGTGAACACTGGGGTGAATAAATTTTAAATCAATTCAAGTATCTCAAAAAAAAAAAAA
 961 A
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' acucuguccaaguacGACGAUa 5'
                         |||||| 
Target 5' ccatgaacggaatacCTGCTAg 3'
412 - 433 120.00 -8.70
2
miRNA  3' acuCUGUCC--AAGUACGACGaua 5'
             |:||||   | | |||||   
Target 5' cgcGGCAGGAACTGAAGCTGCcct 3'
178 - 201 117.00 -12.82
3
miRNA  3' acucUGUC-CAAGUACGA--CGAUa 5'
              || | || :: |||  |||| 
Target 5' cgtcACTGAGTGTG-GCTGGGCTAc 3'
223 - 246 105.00 -6.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM9861190 3 COSMIC
COSM729880 5 COSMIC
COSM4525630 6 COSMIC
COSM5623968 13 COSMIC
COSM165001 25 COSMIC
COSM1308957 77 COSMIC
COSM253862 77 COSMIC
COSM1421788 80 COSMIC
COSN28647187 140 COSMIC
COSN31504263 141 COSMIC
COSN16527781 151 COSMIC
COSN31612835 178 COSMIC
COSN31496196 185 COSMIC
COSN28717389 201 COSMIC
COSN30160411 209 COSMIC
COSN1939674 259 COSMIC
COSN20074756 262 COSMIC
COSN25594122 475 COSMIC
COSN20769442 774 COSMIC
COSN31778279 929 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs749534727 2 dbSNP
rs183848229 6 dbSNP
rs1161044380 9 dbSNP
rs754957376 10 dbSNP
rs750989455 15 dbSNP
rs765949108 21 dbSNP
rs1157577100 22 dbSNP
rs758017674 23 dbSNP
rs1397503189 29 dbSNP
rs1200210161 30 dbSNP
rs1451338950 34 dbSNP
rs752694991 36 dbSNP
rs1207082762 44 dbSNP
rs765571309 49 dbSNP
rs950820848 50 dbSNP
rs762229945 53 dbSNP
rs1285373740 56 dbSNP
rs777055184 60 dbSNP
rs766105548 63 dbSNP
rs1305458128 65 dbSNP
rs775376744 70 dbSNP
rs1233907637 72 dbSNP
rs200235917 74 dbSNP
rs1448865568 78 dbSNP
rs865971646 80 dbSNP
rs761267288 81 dbSNP
rs371584828 82 dbSNP
rs778663043 83 dbSNP
rs199575188 108 dbSNP
rs1417250649 112 dbSNP
rs774783729 114 dbSNP
rs1458028386 119 dbSNP
rs763226743 121 dbSNP
rs1351191906 122 dbSNP
rs1448602145 124 dbSNP
rs1478008269 128 dbSNP
rs771284908 129 dbSNP
rs1195843221 130 dbSNP
rs747841311 136 dbSNP
rs3732473 140 dbSNP
rs747011473 141 dbSNP
rs1486665494 143 dbSNP
rs754057477 150 dbSNP
rs139906955 151 dbSNP
rs1385598688 155 dbSNP
rs146339259 156 dbSNP
rs1176924835 161 dbSNP
rs969969374 167 dbSNP
rs867991228 171 dbSNP
rs1013849086 173 dbSNP
rs1244961606 176 dbSNP
rs746013910 178 dbSNP
rs1031346282 179 dbSNP
rs781246503 180 dbSNP
rs937656914 181 dbSNP
rs557000889 183 dbSNP
rs539917134 185 dbSNP
rs1206854357 192 dbSNP
rs904844557 195 dbSNP
rs73195025 201 dbSNP
rs950267692 203 dbSNP
rs1246493140 207 dbSNP
rs1425767924 209 dbSNP
rs546675545 210 dbSNP
rs114329606 215 dbSNP
rs750481491 219 dbSNP
rs561009223 224 dbSNP
rs1378864737 230 dbSNP
rs1456415781 232 dbSNP
rs572924826 236 dbSNP
rs549290637 237 dbSNP
rs1439755845 238 dbSNP
rs1434917056 242 dbSNP
rs1052024139 250 dbSNP
rs929439529 251 dbSNP
rs762398684 252 dbSNP
rs191260597 261 dbSNP
rs188278908 262 dbSNP
rs1240533085 268 dbSNP
rs942136831 270 dbSNP
rs185079464 275 dbSNP
rs1206651408 276 dbSNP
rs1264783434 277 dbSNP
rs1483432430 281 dbSNP
rs374239934 284 dbSNP
rs980317781 285 dbSNP
rs1184435746 295 dbSNP
rs969879457 301 dbSNP
rs559436677 311 dbSNP
rs775047518 312 dbSNP
rs1466825901 315 dbSNP
rs113597584 318 dbSNP
rs1301942607 320 dbSNP
rs893580676 323 dbSNP
rs955705604 324 dbSNP
rs1411194188 327 dbSNP
rs58683084 336 dbSNP
rs1349272623 338 dbSNP
rs9814348 338 dbSNP
rs1303255901 340 dbSNP
rs904875815 342 dbSNP
rs1484953648 343 dbSNP
rs867538180 347 dbSNP
rs866579633 348 dbSNP
rs6779853 367 dbSNP
rs6765459 370 dbSNP
rs375888810 374 dbSNP
rs78250008 376 dbSNP
rs1427838817 377 dbSNP
rs6765455 380 dbSNP
rs943396554 384 dbSNP
rs1357125332 390 dbSNP
rs60465767 394 dbSNP
rs60388701 395 dbSNP
rs35848662 396 dbSNP
rs1369425693 399 dbSNP
rs1407430324 403 dbSNP
rs1276588556 407 dbSNP
rs954639747 415 dbSNP
rs6774988 416 dbSNP
rs1298945212 419 dbSNP
rs562213931 420 dbSNP
rs1362833553 426 dbSNP
rs1172102423 429 dbSNP
rs753392456 431 dbSNP
rs113095496 432 dbSNP
rs34010338 434 dbSNP
rs1426787022 436 dbSNP
rs1261171872 441 dbSNP
rs1203068751 455 dbSNP
rs1001912572 457 dbSNP
rs1489084892 461 dbSNP
rs3818946 461 dbSNP
rs1451666532 464 dbSNP
rs1239930630 469 dbSNP
rs917122349 471 dbSNP
rs1389136841 473 dbSNP
rs1427341200 475 dbSNP
rs1278117647 476 dbSNP
rs992699019 478 dbSNP
rs1345489704 492 dbSNP
rs1257374595 499 dbSNP
rs1024629193 501 dbSNP
rs1349900241 504 dbSNP
rs1435685639 512 dbSNP
rs1291676843 514 dbSNP
rs1367117110 518 dbSNP
rs955985241 521 dbSNP
rs896094088 530 dbSNP
rs1048464581 539 dbSNP
rs564457558 543 dbSNP
rs567626346 544 dbSNP
rs899333697 546 dbSNP
rs1342865118 548 dbSNP
rs1037872881 550 dbSNP
rs924283016 551 dbSNP
rs142002480 555 dbSNP
rs530678501 559 dbSNP
rs1466561795 561 dbSNP
rs1414218003 566 dbSNP
rs1189609103 570 dbSNP
rs73195023 571 dbSNP
rs1017731229 577 dbSNP
rs1051789373 583 dbSNP
rs1413933550 584 dbSNP
rs2236594 585 dbSNP
rs913876074 588 dbSNP
rs1390701040 589 dbSNP
rs988470200 591 dbSNP
rs1319626069 592 dbSNP
rs140688397 592 dbSNP
rs756294108 604 dbSNP
rs1428893648 620 dbSNP
rs1255269009 621 dbSNP
rs925147074 623 dbSNP
rs1030532571 625 dbSNP
rs750717230 626 dbSNP
rs980564129 627 dbSNP
rs898045549 634 dbSNP
rs969136982 635 dbSNP
rs138816375 642 dbSNP
rs1445601983 648 dbSNP
rs1024660237 655 dbSNP
rs563712004 657 dbSNP
rs951130970 659 dbSNP
rs1338280527 664 dbSNP
rs1258313442 671 dbSNP
rs1414165611 688 dbSNP
rs7625479 692 dbSNP
rs188773838 693 dbSNP
rs899410075 694 dbSNP
rs905196151 695 dbSNP
rs750110529 706 dbSNP
rs1045127250 707 dbSNP
rs1336445522 719 dbSNP
rs949507685 726 dbSNP
rs752073949 728 dbSNP
rs1336617386 729 dbSNP
rs7612496 731 dbSNP
rs150602454 732 dbSNP
rs1171691164 737 dbSNP
rs1352345249 739 dbSNP
rs576006002 740 dbSNP
rs1415823361 747 dbSNP
rs377646141 750 dbSNP
rs769950930 751 dbSNP
rs978703716 754 dbSNP
rs1202509422 755 dbSNP
rs1239147777 758 dbSNP
rs1441469561 760 dbSNP
rs1179320386 765 dbSNP
rs968785722 769 dbSNP
rs1208206994 772 dbSNP
rs141837804 773 dbSNP
rs1472609942 791 dbSNP
rs1238359784 793 dbSNP
rs1361963296 806 dbSNP
rs1478925779 810 dbSNP
rs1200199297 831 dbSNP
rs892463878 832 dbSNP
rs1466724085 841 dbSNP
rs1052444242 849 dbSNP
rs7610069 857 dbSNP
rs925208369 860 dbSNP
rs577363931 861 dbSNP
rs1286473297 863 dbSNP
rs79228566 867 dbSNP
rs1275821988 873 dbSNP
rs1344669586 874 dbSNP
rs143807688 879 dbSNP
rs917719838 882 dbSNP
rs1483125049 889 dbSNP
rs1332270142 890 dbSNP
rs535085837 892 dbSNP
rs73890141 895 dbSNP
rs1392361453 901 dbSNP
rs1322908015 913 dbSNP
rs757125427 914 dbSNP
rs951161602 916 dbSNP
rs1376885970 920 dbSNP
rs79537095 931 dbSNP
rs1156769012 940 dbSNP
rs1392228026 941 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 93109.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
CLIP-seq Support 1 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000381975.3 | 3UTR | CUAAGAUGAUGAUGAUGAUGAUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000381975.3 | 3UTR | CUGCUAAGAUGAUGAUGAUGAUGAUUUUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
180 hsa-miR-4524a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055251 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT055826 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT060573 CCND1 cyclin D1 2 2
MIRT061013 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT064694 CCND2 cyclin D2 2 4
MIRT075268 SNTB2 syntrophin beta 2 2 4
MIRT079668 NAPG NSF attachment protein gamma 2 12
MIRT081651 CCNE1 cyclin E1 2 4
MIRT082996 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083463 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT085755 RIF1 replication timing regulatory factor 1 2 2
MIRT086022 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087431 ZNRF3 zinc and ring finger 3 2 2
MIRT088786 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT089221 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT093696 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT095090 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT096249 CANX calnexin 2 2
MIRT100215 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100746 VEGFA vascular endothelial growth factor A 2 12
MIRT100904 CD2AP CD2 associated protein 2 2
MIRT102647 UBN2 ubinuclein 2 2 10
MIRT103882 FOXK1 forkhead box K1 2 2
MIRT104246 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106310 ZFHX4 zinc finger homeobox 4 2 6
MIRT107696 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT114943 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117671 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT133799 SKI SKI proto-oncogene 2 2
MIRT140167 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT142279 DCTN5 dynactin subunit 5 2 8
MIRT143288 N4BP1 NEDD4 binding protein 1 2 2
MIRT165939 CREBRF CREB3 regulatory factor 2 2
MIRT175251 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT186381 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT191470 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT196480 TAOK1 TAO kinase 1 2 2
MIRT201470 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204615 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204646 MOB4 MOB family member 4, phocein 2 8
MIRT204749 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206031 NUP50 nucleoporin 50 2 6
MIRT211196 FGF2 fibroblast growth factor 2 2 4
MIRT229353 ZNF449 zinc finger protein 449 2 2
MIRT247138 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT249461 ZNF691 zinc finger protein 691 2 4
MIRT256314 CDC42SE2 CDC42 small effector 2 2 2
MIRT258419 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265083 CHEK1 checkpoint kinase 1 2 2
MIRT270561 SETD1B SET domain containing 1B 2 2
MIRT274749 RAB3IP RAB3A interacting protein 2 2
MIRT277515 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT289642 CBX2 chromobox 2 2 2
MIRT301001 MTMR3 myotubularin related protein 3 2 2
MIRT307149 CTDSPL CTD small phosphatase like 2 4
MIRT309021 USP53 ubiquitin specific peptidase 53 2 2
MIRT314100 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT319338 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320619 ZNRF2 zinc and ring finger 2 2 2
MIRT324285 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT446498 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT448437 TLL1 tolloid like 1 2 2
MIRT461537 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463162 ZNF367 zinc finger protein 367 2 10
MIRT463493 ZC3H10 zinc finger CCCH-type containing 10 2 2
MIRT465154 TSC22D2 TSC22 domain family member 2 2 2
MIRT466418 TFAP2A transcription factor AP-2 alpha 2 8
MIRT468278 SFT2D2 SFT2 domain containing 2 2 2
MIRT469399 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471941 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT473688 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT479618 CDC25A cell division cycle 25A 2 2
MIRT482098 AKT3 AKT serine/threonine kinase 3 2 4
MIRT483995 ATAD5 ATPase family, AAA domain containing 5 2 12
MIRT485205 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT498763 C3orf38 chromosome 3 open reading frame 38 2 8
MIRT498961 ORC4 origin recognition complex subunit 4 2 8
MIRT499440 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500080 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500305 ZNF622 zinc finger protein 622 2 8
MIRT500410 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500789 TLK1 tousled like kinase 1 2 6
MIRT500930 SRPR SRP receptor alpha subunit 2 6
MIRT500943 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501068 SMAD7 SMAD family member 7 2 8
MIRT501711 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT502627 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502910 CDCA4 cell division cycle associated 4 2 8
MIRT502935 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504531 ZNF620 zinc finger protein 620 2 6
MIRT505106 YTHDC1 YTH domain containing 1 2 6
MIRT505337 TMEM245 transmembrane protein 245 2 6
MIRT505383 TMEM100 transmembrane protein 100 2 2
MIRT505678 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506157 PLAG1 PLAG1 zinc finger 2 8
MIRT506183 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506475 MYO5A myosin VA 2 6
MIRT506826 KIF23 kinesin family member 23 2 6
MIRT507160 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT507511 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT507845 CCNE2 cyclin E2 2 6
MIRT510403 ZNF507 zinc finger protein 507 2 2
MIRT518078 TRIM35 tripartite motif containing 35 2 2
MIRT518982 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521045 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521190 SBNO1 strawberry notch homolog 1 2 6
MIRT522088 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT524846 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT527787 TMEM44 transmembrane protein 44 2 4
MIRT537803 EFNB2 ephrin B2 2 4
MIRT540830 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541140 PISD phosphatidylserine decarboxylase 2 2
MIRT541419 CBX4 chromobox 4 2 2
MIRT543517 PRSS21 protease, serine 21 2 2
MIRT543824 GSG1 germ cell associated 1 2 2
MIRT544959 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545179 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545335 CCDC83 coiled-coil domain containing 83 2 2
MIRT545518 RSL24D1 ribosomal L24 domain containing 1 2 2
MIRT545670 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545931 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546102 USP48 ubiquitin specific peptidase 48 2 4
MIRT546598 SALL1 spalt like transcription factor 1 2 4
MIRT546626 RTN4 reticulon 4 2 2
MIRT547651 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547987 HCFC2 host cell factor C2 2 4
MIRT548717 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548931 CDK17 cyclin dependent kinase 17 2 2
MIRT549067 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549266 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT550460 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550806 FAM229B family with sequence similarity 229 member B 2 2
MIRT552024 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552334 ZNF704 zinc finger protein 704 2 2
MIRT552732 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553795 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554694 RNF149 ring finger protein 149 2 2
MIRT555133 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555264 PRDM4 PR/SET domain 4 2 2
MIRT556848 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557474 GPR27 G protein-coupled receptor 27 2 4
MIRT558018 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558498 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558579 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558610 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT558650 CNKSR3 CNKSR family member 3 2 2
MIRT558986 CA8 carbonic anhydrase 8 2 2
MIRT559141 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559327 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT562021 LANCL1 LanC like 1 2 2
MIRT562869 KIAA1456 KIAA1456 2 2
MIRT563074 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563496 DLGAP3 DLG associated protein 3 2 2
MIRT563890 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564311 CCNT1 cyclin T1 2 2
MIRT564942 XKR7 XK related 7 2 2
MIRT564979 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565423 TEF TEF, PAR bZIP transcription factor 2 2
MIRT566824 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571961 KIF5B kinesin family member 5B 2 2
MIRT575877 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT576523 Txlna taxilin alpha 2 2
MIRT614693 TRAK1 trafficking kinesin protein 1 2 2
MIRT616065 ZC3H14 zinc finger CCCH-type containing 14 2 2
MIRT618838 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT624626 ATXN2 ataxin 2 2 2
MIRT624652 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT640314 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT659248 CUL3 cullin 3 2 2
MIRT680972 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682261 RS1 retinoschisin 1 2 2
MIRT682505 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693904 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT699214 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT699373 SLC30A6 solute carrier family 30 member 6 2 2
MIRT699451 SLC16A9 solute carrier family 16 member 9 2 2
MIRT701230 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702849 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT706163 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT718990 UTP15 UTP15, small subunit processome component 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4524a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4524a-5p Cetuximab resistant tissue (colorectal carcinoma)

Error report submission