miRTarBase - #MIRT527844


—
pre-miRNA Information
pre-miRNA hsa-mir-6131   
Genomic Coordinates chr5: 10478037 - 10478145
Description Homo sapiens miR-6131 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6131
Sequence 71| GGCUGGUCAGAUGGGAGUG |89
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 11 5 + 10478117 29233923 MiREDiBase
A-to-I 16 5 + 10478122 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs957913380 1 dbSNP
rs996083508 3 dbSNP
rs1304832380 16 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol RDH11   
Synonyms ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1
Description retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
Transcript NM_016026   
Expression
Putative miRNA Targets on RDH11
3'UTR of RDH11
(miRNA target sites are highlighted)		 
>RDH11|NM_016026|3'UTR
   1 CAGGCAGTGCCAGTTGGACCCAAGAGAAGACTGCAGCAGACTACACAGTACTTCTTGTCAAAATGATTCTCCTTCAAGGT
  81 TTTCAAAACCTTTAGCACAAAGAGAGCAAAACCTTCCAGCCTTGCCTGCTTGGTGTCCAGTTAAAACTCAGTGTACTGCC
 161 AGATTCGTCTAAATGTCTGTCATGTCCAGATTTACTTTGCTTCTGTTACTGCCAGAGTTACTAGAGATATCATAATAGGA
 241 TAAGAAGACCCTCATATGACCTGCACAGCTCATTTTCCTTCTGAAAGAAACTACTACCTAGGAGAATCTAAGCTATAGCA
 321 GGGATGATTTATGCAAATTTGAACTAGCTTCTTTGTTCACAATTCAGTTCCTCCCAACCAACCAGTCTTCACTTCAAGAG
 401 GGCCACACTGCAACCTCAGCTTAACATGAATAACAAAGACTGGCTCAGGAGCAGGGCTTGCCCAGGCATGGTGGATCACC
 481 GGAGGTCAGTAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCTACTAAAAATTGTGTATATCTTTGTGTGT
 561 CTTCCTGTTTATGTGTGCCAAGGGAGTATTTTCACAAAGTTCAAAACAGCCACAATAATCAGAGATGGAGCAAACCAGTG
 641 CCATCCAGTCTTTATGCAAATGAAATGCTGCAAAGGGAAGCAGATTCTGTATATGTTGGTAACTACCCACCAAGAGCACA
 721 TGGGTAGCAGGGAAGAAGTAAAAAAAGAGAAGGAGAATACTGGAAGATAATGCACAAAATGAAGGGACTAGTTAAGGATT
 801 AACTAGCCCTTTAAGGATTAACTAGTTAAGGATTAATAGCAAAAGATATTAAATATGCTAACATAGCTATGGAGGAATTG
 881 AGGGCAAGCACCCAGGACTGATGAGGTCTTAACAAAAACCAGTGTGGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAATCC
 961 TAAAAACAAACAAACAAAAAAAACAATTCTTCATTCAGAAAAATTATCTTAGGGACTGATATTGGTAATTATGGTCAATT
1041 TAATAATATTTTGGGGCATTTCCTTACATTGTCTTGACAAGATTAAAATGTCTGTGCCAAAATTTTGTATTTTATTTGGA
1121 GACTTCTTATCAAAAGTAATGCTGCCAAAGGAAGTCTAAGGAATTAGTAGTGTTCCCATCACTTGTTTGGAGTGTGCTAT
1201 TCTAAAAGATTTTGATTTCCTGGAATGACAATTATATTTTAACTTTGGTGGGGGAAAGAGTTATAGGACCACAGTCTTCA
1281 CTTCTGATACTTGTAAATTAATCTTTTATTGCACTTGTTTTGACCATTAAGCTATATGTTTAGAAATGGTCATTTTACGG
1361 AAAAATTAGAAAAATTCTGATAATAGTGCAGAATAAATGAATTAATGTTTTACTTAATTTATATTGAACTGTCAATGACA
1441 AATAAAAATTCTTTTTGATTATTTTTTGTTTTCATTTACCAGAATAAAAACTAAGAATTAAAAGTTTGATTACAGTCAAA
1521 AAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gugAGGGUAGACUGGUCGg 5'
             |:| |   ||||||| 
Target 5' tagTTCAA---GACCAGCc 3'
 490 - 505 141.00 -15.20
2 
miRNA  3' guGAGGGUAGACUGGUCGg 5'
            | |:||| ||||| || 
Target 5' gaCCCTCATATGACCTGCa 3'
 247 - 265 133.00 -16.50
3 
miRNA  3' guGAGGGUAGACUGGUCGg 5'
            |||||| |  |||||: 
Target 5' tcCTCCCAACCAACCAGTc 3'
 369 - 387 121.00 -20.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31578979 5 COSMIC
COSN26991892 26 COSMIC
COSN30141940 38 COSMIC
COSN26577395 213 COSMIC
COSN21132772 269 COSMIC
COSN17182785 531 COSMIC
COSN31960998 866 COSMIC
COSN20092850 967 COSMIC
COSN20092849 971 COSMIC
COSN17488756 975 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs745661753 1 dbSNP
rs778641026 4 dbSNP
rs770871889 8 dbSNP
rs540437881 13 dbSNP
rs926431321 16 dbSNP
rs1227166328 24 dbSNP
rs777952092 28 dbSNP
rs756297415 34 dbSNP
rs752905689 39 dbSNP
rs1303554656 46 dbSNP
rs1052293371 47 dbSNP
rs370763979 50 dbSNP
rs1335925552 59 dbSNP
rs980638270 59 dbSNP
rs1285742819 61 dbSNP
rs946586137 73 dbSNP
rs1466003256 76 dbSNP
rs1193247891 80 dbSNP
rs1236446127 87 dbSNP
rs573354491 90 dbSNP
rs1471766108 93 dbSNP
rs1164932938 94 dbSNP
rs1418236197 94 dbSNP
rs1044673698 102 dbSNP
rs1158656015 107 dbSNP
rs1316726329 118 dbSNP
rs1459069613 123 dbSNP
rs771726877 128 dbSNP
rs1340018623 132 dbSNP
rs956720824 135 dbSNP
rs554987920 136 dbSNP
rs747732542 139 dbSNP
rs976808616 143 dbSNP
rs1356454363 144 dbSNP
rs1467772105 147 dbSNP
rs1430793773 149 dbSNP
rs964136396 151 dbSNP
rs778516614 152 dbSNP
rs952227862 157 dbSNP
rs1018823493 162 dbSNP
rs1205423397 166 dbSNP
rs1277209275 166 dbSNP
rs1005719183 167 dbSNP
rs754395671 174 dbSNP
rs966243892 179 dbSNP
rs543287383 182 dbSNP
rs1413988491 184 dbSNP
rs1471279842 186 dbSNP
rs751645646 190 dbSNP
rs1285199640 203 dbSNP
rs528818260 204 dbSNP
rs1321417824 215 dbSNP
rs1265090120 220 dbSNP
rs1224623916 222 dbSNP
rs575584283 223 dbSNP
rs1011439079 230 dbSNP
rs1025926590 239 dbSNP
rs1409812827 249 dbSNP
rs1433313066 255 dbSNP
rs557383929 268 dbSNP
rs539184532 269 dbSNP
rs1273903874 272 dbSNP
rs1030833344 276 dbSNP
rs1342211579 277 dbSNP
rs754415535 291 dbSNP
rs1333016295 293 dbSNP
rs1482683024 294 dbSNP
rs189705004 296 dbSNP
rs1253626052 300 dbSNP
rs1419475675 301 dbSNP
rs1182748393 306 dbSNP
rs1377248402 307 dbSNP
rs138477519 310 dbSNP
rs1175585338 329 dbSNP
rs1003334899 348 dbSNP
rs993554371 360 dbSNP
rs1176562833 374 dbSNP
rs897474368 377 dbSNP
rs1306730921 381 dbSNP
rs780392035 391 dbSNP
rs535890232 397 dbSNP
rs34298206 399 dbSNP
rs1392368077 400 dbSNP
rs1417269359 403 dbSNP
rs553468996 405 dbSNP
rs116644560 406 dbSNP
rs567432351 408 dbSNP
rs1340852968 425 dbSNP
rs1045299434 426 dbSNP
rs946606264 438 dbSNP
rs1276724849 446 dbSNP
rs915129629 452 dbSNP
rs74848574 453 dbSNP
rs1265070855 460 dbSNP
rs1450077446 463 dbSNP
rs767931015 480 dbSNP
rs1253638762 481 dbSNP
rs537340782 488 dbSNP
rs762161757 496 dbSNP
rs1375256817 498 dbSNP
rs976754722 501 dbSNP
rs1048134718 503 dbSNP
rs1389112955 508 dbSNP
rs569355803 514 dbSNP
rs964081928 523 dbSNP
rs11555751 526 dbSNP
rs1326188029 531 dbSNP
rs1363775886 532 dbSNP
rs911347792 535 dbSNP
rs11555752 542 dbSNP
rs1432221223 547 dbSNP
rs984685329 551 dbSNP
rs1307989497 555 dbSNP
rs952934566 555 dbSNP
rs1026252935 559 dbSNP
rs550963599 568 dbSNP
rs1263388580 578 dbSNP
rs1358215347 580 dbSNP
rs1215733564 589 dbSNP
rs1424450104 591 dbSNP
rs1359350818 606 dbSNP
rs1271501127 607 dbSNP
rs150056845 608 dbSNP
rs7410 615 dbSNP
rs1340423957 617 dbSNP
rs960290708 619 dbSNP
rs543714149 620 dbSNP
rs912122849 629 dbSNP
rs1463368987 633 dbSNP
rs1003203376 635 dbSNP
rs1166149507 640 dbSNP
rs904933919 647 dbSNP
rs1387421744 655 dbSNP
rs1044848674 662 dbSNP
rs1290107834 673 dbSNP
rs1362045493 688 dbSNP
rs1395325633 691 dbSNP
rs1011136541 692 dbSNP
rs547443174 693 dbSNP
rs1357083789 699 dbSNP
rs1233643094 703 dbSNP
rs1267322661 706 dbSNP
rs7765 709 dbSNP
rs1213999551 711 dbSNP
rs186380369 716 dbSNP
rs1262504322 731 dbSNP
rs542992239 733 dbSNP
rs1200339950 746 dbSNP
rs935199197 750 dbSNP
rs1476500150 751 dbSNP
rs989580377 759 dbSNP
rs1445386459 761 dbSNP
rs956968338 763 dbSNP
rs1471366706 767 dbSNP
rs1160857190 772 dbSNP
rs1059226 774 dbSNP
rs776699207 785 dbSNP
rs575892361 788 dbSNP
rs1465134613 793 dbSNP
rs1300611009 799 dbSNP
rs371030190 805 dbSNP
rs1415386220 816 dbSNP
rs1287484635 821 dbSNP
rs1348405878 824 dbSNP
rs967110293 826 dbSNP
rs1309455080 837 dbSNP
rs1330729186 841 dbSNP
rs1209475576 845 dbSNP
rs1059238 847 dbSNP
rs911280334 851 dbSNP
rs1161411705 859 dbSNP
rs1023490061 862 dbSNP
rs1446275088 869 dbSNP
rs1178534303 875 dbSNP
rs374553025 879 dbSNP
rs370517528 882 dbSNP
rs1012607405 895 dbSNP
rs1387303541 899 dbSNP
rs1173330259 905 dbSNP
rs141648914 908 dbSNP
rs1184516328 913 dbSNP
rs984199441 915 dbSNP
rs1307359045 919 dbSNP
rs1480311879 920 dbSNP
rs1368423413 925 dbSNP
rs1231264706 927 dbSNP
rs1431869015 927 dbSNP
rs1406027032 928 dbSNP
rs1298579062 929 dbSNP
rs1374308560 929 dbSNP
rs1453085453 929 dbSNP
rs1438933267 930 dbSNP
rs1291738975 931 dbSNP
rs1218924977 940 dbSNP
rs1244207572 945 dbSNP
rs1362112457 948 dbSNP
rs1315299273 949 dbSNP
rs1222851193 950 dbSNP
rs1491357727 957 dbSNP
rs1167843731 958 dbSNP
rs1170869798 958 dbSNP
rs1191366365 958 dbSNP
rs1207039915 958 dbSNP
rs1233879567 958 dbSNP
rs1254275498 958 dbSNP
rs1264891632 958 dbSNP
rs1274589509 958 dbSNP
rs1306306727 958 dbSNP
rs1335276962 958 dbSNP
rs1349091427 958 dbSNP
rs1388218020 958 dbSNP
rs1411644422 958 dbSNP
rs1435950709 958 dbSNP
rs1454354440 958 dbSNP
rs1487951683 958 dbSNP
rs1491312953 958 dbSNP
rs71129846 958 dbSNP
rs768377756 958 dbSNP
rs1274698283 959 dbSNP
rs1491192256 959 dbSNP
rs775490684 959 dbSNP
rs1491262555 960 dbSNP
rs1471024839 961 dbSNP
rs1280803849 967 dbSNP
rs377025166 967 dbSNP
rs888116194 967 dbSNP
rs1442355618 968 dbSNP
rs879204625 971 dbSNP
rs199532098 975 dbSNP
rs1349210156 976 dbSNP
rs796331583 977 dbSNP
rs1426316784 978 dbSNP
rs1048495271 979 dbSNP
rs145780940 979 dbSNP
rs554367375 979 dbSNP
rs370783174 982 dbSNP
rs1231814480 984 dbSNP
rs1271312416 984 dbSNP
rs1295556803 984 dbSNP
rs1335066973 984 dbSNP
rs1378852719 984 dbSNP
rs918732129 986 dbSNP
rs929665114 986 dbSNP
rs1281450485 987 dbSNP
rs1418746809 993 dbSNP
rs1448243485 994 dbSNP
rs1216357783 998 dbSNP
rs1236797019 1007 dbSNP
rs896879203 1014 dbSNP
rs1189782137 1016 dbSNP
rs1418392029 1017 dbSNP
rs972879156 1022 dbSNP
rs1158227083 1024 dbSNP
rs960279086 1034 dbSNP
rs1402560253 1043 dbSNP
rs759213478 1049 dbSNP
rs1035937925 1054 dbSNP
rs1003149614 1059 dbSNP
rs1315093289 1064 dbSNP
rs1470580564 1065 dbSNP
rs768799827 1068 dbSNP
rs969104489 1077 dbSNP
rs1023739202 1083 dbSNP
rs760549319 1088 dbSNP
rs1268782914 1090 dbSNP
rs1227343328 1094 dbSNP
rs1277440325 1095 dbSNP
rs1220987237 1098 dbSNP
rs1352444388 1100 dbSNP
rs1490922792 1103 dbSNP
rs376098006 1111 dbSNP
rs1214569113 1112 dbSNP
rs1484648084 1116 dbSNP
rs1212940159 1119 dbSNP
rs747016215 1124 dbSNP
rs1314793806 1126 dbSNP
rs1285975439 1127 dbSNP
rs199566697 1129 dbSNP
rs865866963 1129 dbSNP
rs1471310723 1130 dbSNP
rs986389468 1133 dbSNP
rs1394557839 1136 dbSNP
rs1433335941 1140 dbSNP
rs578049675 1142 dbSNP
rs866767995 1144 dbSNP
rs1376399833 1145 dbSNP
rs772996305 1148 dbSNP
rs776086010 1152 dbSNP
rs1327325427 1154 dbSNP
rs1337148091 1164 dbSNP
rs1442572638 1170 dbSNP
rs77173642 1172 dbSNP
rs1052226811 1177 dbSNP
rs1236344425 1193 dbSNP
rs1234465360 1196 dbSNP
rs956719996 1201 dbSNP
rs1193838837 1204 dbSNP
rs924005765 1214 dbSNP
rs1345857026 1233 dbSNP
rs999396751 1242 dbSNP
rs1288106040 1243 dbSNP
rs771813116 1244 dbSNP
rs1182811672 1247 dbSNP
rs553532336 1251 dbSNP
rs1252395181 1261 dbSNP
rs1452691669 1264 dbSNP
rs1175643126 1275 dbSNP
rs746475084 1284 dbSNP
rs1461973831 1285 dbSNP
rs377347610 1290 dbSNP
rs1399087561 1292 dbSNP
rs970522682 1313 dbSNP
rs942632533 1314 dbSNP
rs1442431870 1337 dbSNP
rs1303574075 1339 dbSNP
rs1012084377 1351 dbSNP
rs1225243521 1352 dbSNP
rs747858588 1358 dbSNP
rs1048885720 1359 dbSNP
rs1333167541 1369 dbSNP
rs1428688110 1387 dbSNP
rs1196559849 1395 dbSNP
rs994213852 1399 dbSNP
rs1197816107 1407 dbSNP
rs1467347139 1408 dbSNP
rs773832825 1420 dbSNP
rs1253779937 1429 dbSNP
rs896846724 1447 dbSNP
rs1481716881 1452 dbSNP
rs1375093429 1453 dbSNP
rs1269995719 1461 dbSNP
rs1186274165 1464 dbSNP
rs1485131947 1466 dbSNP
rs1040801018 1468 dbSNP
rs1262123445 1468 dbSNP
rs931377540 1500 dbSNP
rs1325993776 1513 dbSNP
rs778405892 1514 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 51109.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gugaggguagaCUGGUCGg 5'
                     |::|||: 
Target 5' ----------aGGUCAGUa 3'
 		1 - 9
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000381346.4 | 3UTR | AGGUCAGUAGUUCAAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
212 hsa-miR-6131 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT077630 IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 2 6
MIRT177175 ARL5B ADP ribosylation factor like GTPase 5B 2 4
MIRT442431 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 6
MIRT478684 CSRP2 cysteine and glycine rich protein 2 2 4
MIRT484891 ZNF607 zinc finger protein 607 2 2
MIRT487161 IFRD1 interferon related developmental regulator 1 2 10
MIRT488196 MAT1A methionine adenosyltransferase 1A 2 2
MIRT495470 ALDOA aldolase, fructose-bisphosphate A 2 2
MIRT497190 DUSP18 dual specificity phosphatase 18 2 2
MIRT498387 LRRC58 leucine rich repeat containing 58 2 2
MIRT499716 PAGR1 PAXIP1 associated glutamate rich protein 1 2 10
MIRT507261 FERMT2 fermitin family member 2 2 2
MIRT507290 FEM1B fem-1 homolog B 2 2
MIRT507537 DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 2 6
MIRT508063 ARHGAP42 Rho GTPase activating protein 42 2 4
MIRT510064 C12orf49 chromosome 12 open reading frame 49 2 4
MIRT510825 SBNO1 strawberry notch homolog 1 2 4
MIRT511209 LNPEP leucyl and cystinyl aminopeptidase 2 4
MIRT511827 H2AFX H2A histone family member X 2 4
MIRT512063 DEK DEK proto-oncogene 2 6
MIRT513501 NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 2 6
MIRT513634 TP53INP2 tumor protein p53 inducible nuclear protein 2 2 2
MIRT515274 NUCB1 nucleobindin 1 2 6
MIRT519380 FKBP14 FK506 binding protein 14 2 4
MIRT519521 ZNF8 zinc finger protein 8 2 2
MIRT520633 NPM3 nucleophosmin/nucleoplasmin 3 2 6
MIRT520952 SRSF10 serine and arginine rich splicing factor 10 2 2
MIRT522073 ORAI2 ORAI calcium release-activated calcium modulator 2 2 4
MIRT527844 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2 2
MIRT530067 VN1R1 vomeronasal 1 receptor 1 2 2
MIRT530226 ZMAT4 zinc finger matrin-type 4 2 2
MIRT530637 PPIC peptidylprolyl isomerase C 2 4
MIRT530677 CHRNB1 cholinergic receptor nicotinic beta 1 subunit 2 4
MIRT531681 MYO3A myosin IIIA 2 2
MIRT532175 SEC14L5 SEC14 like lipid binding 5 2 4
MIRT534235 SLC25A16 solute carrier family 25 member 16 2 4
MIRT535116 PLXNA2 plexin A2 2 2
MIRT535562 OMD osteomodulin 2 2
MIRT536483 KIAA1468 KIAA1468 2 2
MIRT538368 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT550667 TRAF1 TNF receptor associated factor 1 2 2
MIRT554736 RHOC ras homolog family member C 2 2
MIRT556522 LIN52 lin-52 DREAM MuvB core complex component 2 2
MIRT559269 BAG4 BCL2 associated athanogene 4 2 2
MIRT560957 FAM35A family with sequence similarity 35 member A 2 2
MIRT564728 ZNF268 zinc finger protein 268 2 2
MIRT573116 NUBP1 nucleotide binding protein 1 2 2
MIRT573891 MKI67 marker of proliferation Ki-67 2 2
MIRT576641 Mill2 MHC I like leukocyte 2 1 1
MIRT615883 FBXO17 F-box protein 17 2 2
MIRT618203 C22orf39 chromosome 22 open reading frame 39 2 2
MIRT620108 HARBI1 harbinger transposase derived 1 2 2
MIRT621185 FAM153B family with sequence similarity 153 member B 2 2
MIRT621573 ZBTB43 zinc finger and BTB domain containing 43 2 2
MIRT623753 GRID1 glutamate ionotropic receptor delta type subunit 1 2 2
MIRT624057 EIF4E eukaryotic translation initiation factor 4E 2 2
MIRT625013 TMIGD2 transmembrane and immunoglobulin domain containing 2 2 2
MIRT626071 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT627872 PAN2 PAN2 poly(A) specific ribonuclease subunit 2 2
MIRT629302 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT629862 GATAD1 GATA zinc finger domain containing 1 2 2
MIRT630442 IDE insulin degrading enzyme 2 2
MIRT630997 ZNF573 zinc finger protein 573 2 2
MIRT631091 UQCRB ubiquinol-cytochrome c reductase binding protein 2 2
MIRT631280 SGSM1 small G protein signaling modulator 1 2 2
MIRT631528 MYO6 myosin VI 2 2
MIRT631641 WDR91 WD repeat domain 91 2 4
MIRT631822 TMEM154 transmembrane protein 154 2 2
MIRT632776 LZIC leucine zipper and CTNNBIP1 domain containing 2 2
MIRT633277 FGFR1OP2 FGFR1 oncogene partner 2 2 2
MIRT633655 SLC28A1 solute carrier family 28 member 1 2 2
MIRT634070 PLIN3 perilipin 3 2 2
MIRT634155 YME1L1 YME1 like 1 ATPase 2 2
MIRT634224 TMEM132B transmembrane protein 132B 2 2
MIRT636400 MYO5A myosin VA 2 2
MIRT638677 GCLM glutamate-cysteine ligase modifier subunit 2 2
MIRT638736 FAXC failed axon connections homolog 2 2
MIRT640229 TOMM40 translocase of outer mitochondrial membrane 40 2 2
MIRT640302 PRR13 proline rich 13 2 2
MIRT641123 NPHP3 nephrocystin 3 2 2
MIRT643418 ERVMER34-1 endogenous retrovirus group MER34 member 1, envelope 2 2
MIRT644310 NFKBID NFKB inhibitor delta 2 2
MIRT644343 MPV17L MPV17 mitochondrial inner membrane protein like 2 2
MIRT645734 POLR3A RNA polymerase III subunit A 2 2
MIRT648055 TRMT10C tRNA methyltransferase 10C, mitochondrial RNase P subunit 2 2
MIRT649461 UBA5 ubiquitin like modifier activating enzyme 5 2 2
MIRT650006 KLB klotho beta 2 2
MIRT650565 YIPF4 Yip1 domain family member 4 2 2
MIRT652638 TIMM10 translocase of inner mitochondrial membrane 10 2 2
MIRT653886 SGK3 serum/glucocorticoid regulated kinase family member 3 2 2
MIRT655365 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT659113 DENND6A DENN domain containing 6A 2 2
MIRT659516 CHST3 carbohydrate sulfotransferase 3 2 2
MIRT659945 C8orf44-SGK3 C8orf44-SGK3 readthrough 2 2
MIRT661382 RHCG Rh family C glycoprotein 2 2
MIRT663106 NPR1 natriuretic peptide receptor 1 2 2
MIRT663756 ZNF285 zinc finger protein 285 2 2
MIRT664553 MKI67IP nucleolar protein interacting with the FHA domain of MKI67 1 1
MIRT666191 SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 2 2
MIRT666793 PSMD1 proteasome 26S subunit, non-ATPase 1 2 2
MIRT668751 DDX19B DEAD-box helicase 19B 2 2
MIRT669600 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT669703 AAK1 AP2 associated kinase 1 2 2
MIRT669922 LRPAP1 LDL receptor related protein associated protein 1 2 2
MIRT670002 GPR156 G protein-coupled receptor 156 2 4
MIRT670047 RPP14 ribonuclease P/MRP subunit p14 2 2
MIRT670296 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT670385 EMP2 epithelial membrane protein 2 2 2
MIRT670566 GLTP glycolipid transfer protein 2 2
MIRT671059 KIF1B kinesin family member 1B 2 2
MIRT671080 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT671303 RABGAP1L RAB GTPase activating protein 1 like 2 2
MIRT671803 WISP3 WNT1 inducible signaling pathway protein 3 2 2
MIRT671954 SPPL3 signal peptide peptidase like 3 2 2
MIRT671991 OSTF1 osteoclast stimulating factor 1 2 2
MIRT672090 WDR5B WD repeat domain 5B 2 2
MIRT672269 SHE Src homology 2 domain containing E 2 2
MIRT672445 TTPAL alpha tocopherol transfer protein like 2 2
MIRT672450 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT673649 CYCS cytochrome c, somatic 2 2
MIRT673998 KCNN3 potassium calcium-activated channel subfamily N member 3 2 2
MIRT674052 ATXN3 ataxin 3 2 2
MIRT674243 NUP62 nucleoporin 62 2 2
MIRT674433 MIOX myo-inositol oxygenase 2 4
MIRT674474 BCL2L15 BCL2 like 15 2 2
MIRT675467 NUBPL nucleotide binding protein like 2 2
MIRT675666 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT675976 FAM126B family with sequence similarity 126 member B 2 2
MIRT676063 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT676118 SCIMP SLP adaptor and CSK interacting membrane protein 2 2
MIRT676237 PARP2 poly(ADP-ribose) polymerase 2 2 2
MIRT676256 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676321 FBXL2 F-box and leucine rich repeat protein 2 2 2
MIRT676739 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT676903 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT677112 SS18L1 SS18L1, nBAF chromatin remodeling complex subunit 2 2
MIRT677321 PIGO phosphatidylinositol glycan anchor biosynthesis class O 2 2
MIRT677460 PDLIM3 PDZ and LIM domain 3 2 2
MIRT677578 TRIM65 tripartite motif containing 65 2 2
MIRT677642 HAUS2 HAUS augmin like complex subunit 2 2 2
MIRT677735 MOB4 MOB family member 4, phocein 2 2
MIRT677828 TSPYL1 TSPY like 1 2 2
MIRT678078 EIF2A eukaryotic translation initiation factor 2A 2 2
MIRT678137 SEC24D SEC24 homolog D, COPII coat complex component 2 2
MIRT678157 ZNF724P zinc finger protein 724 2 2
MIRT678255 FXN frataxin 2 2
MIRT678321 FBLIM1 filamin binding LIM protein 1 2 2
MIRT678414 ANKRD36 ankyrin repeat domain 36 2 2
MIRT678596 ARPC2 actin related protein 2/3 complex subunit 2 2 2
MIRT678826 PDE6A phosphodiesterase 6A 2 2
MIRT678939 MYADM myeloid associated differentiation marker 2 2
MIRT679045 CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2 2
MIRT679200 FLVCR1 feline leukemia virus subgroup C cellular receptor 1 2 2
MIRT679204 FAM9B family with sequence similarity 9 member B 2 2
MIRT679219 MAN2A2 mannosidase alpha class 2A member 2 2 2
MIRT679251 ZNF34 zinc finger protein 34 2 2
MIRT679315 NPHP1 nephrocystin 1 2 2
MIRT679484 CYTIP cytohesin 1 interacting protein 2 2
MIRT679550 LIPG lipase G, endothelial type 2 2
MIRT679624 TTC31 tetratricopeptide repeat domain 31 2 2
MIRT679646 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT679757 TLR6 toll like receptor 6 2 2
MIRT680123 ZNF576 zinc finger protein 576 2 2
MIRT680183 ZNF554 zinc finger protein 554 2 2
MIRT685770 ZNF426 zinc finger protein 426 2 2
MIRT687438 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT688384 ENAH ENAH, actin regulator 2 2
MIRT689668 RBM23 RNA binding motif protein 23 2 2
MIRT690030 CCDC90B coiled-coil domain containing 90B 2 2
MIRT691060 CRCP CGRP receptor component 2 2
MIRT691444 CXorf36 chromosome X open reading frame 36 2 2
MIRT691544 FLYWCH2 FLYWCH family member 2 2 2
MIRT691725 LARS leucyl-tRNA synthetase 2 2
MIRT692632 SUSD1 sushi domain containing 1 2 2
MIRT693822 BACE2 beta-site APP-cleaving enzyme 2 2 2
MIRT693861 IYD iodotyrosine deiodinase 2 2
MIRT693974 ZNF70 zinc finger protein 70 2 2
MIRT694143 CYP27C1 cytochrome P450 family 27 subfamily C member 1 2 2
MIRT695485 TRAT1 T-cell receptor associated transmembrane adaptor 1 2 2
MIRT695542 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 2
MIRT695598 TMEM199 transmembrane protein 199 2 2
MIRT696001 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT696017 TYRO3 TYRO3 protein tyrosine kinase 2 2
MIRT696309 NIP7 NIP7, nucleolar pre-rRNA processing protein 2 2
MIRT696397 CORO7 coronin 7 2 2
MIRT696594 ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2 2
MIRT698043 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT698136 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT698287 TMEM2 transmembrane protein 2 2 2
MIRT702556 KBTBD6 kelch repeat and BTB domain containing 6 2 2
MIRT703017 HEATR5A HEAT repeat containing 5A 2 2
MIRT705116 C4orf29 abhydrolase domain containing 18 2 2
MIRT706301 NT5C2 5'-nucleotidase, cytosolic II 2 2
MIRT706609 CYB5B cytochrome b5 type B 2 2
MIRT706725 RFK riboflavin kinase 2 2
MIRT708651 LYRM7 LYR motif containing 7 2 2
MIRT710149 MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like 2 2
MIRT710519 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT711263 CYB561A3 cytochrome b561 family member A3 2 2
MIRT711872 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT714282 KIF1C kinesin family member 1C 2 2
MIRT716605 MPPED1 metallophosphoesterase domain containing 1 2 2
MIRT720435 C19orf47 chromosome 19 open reading frame 47 2 2
MIRT720611 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT720615 PIANP PILR alpha associated neural protein 2 2
MIRT722155 ARHGAP40 Rho GTPase activating protein 40 2 2
MIRT722287 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT722754 SIRPB2 signal regulatory protein beta 2 2 2
MIRT723294 MOGAT1 monoacylglycerol O-acyltransferase 1 2 2
MIRT723839 IL7R interleukin 7 receptor 2 2
MIRT724379 NEK8 NIMA related kinase 8 2 2
MIRT725335 NEUROD1 neuronal differentiation 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6131 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-6131 Temozolomide 5394 NSC362856 approved sensitive cell line (U251)
hsa-miR-6131 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-6131 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-6131 Osimertinib 71496458 NSC779217 approved resistant cell line (H1975)
hsa-miR-6131 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-6131 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

Error report submission