miRTarBase - #MIRT529558


—
pre-miRNA Information
pre-miRNA hsa-mir-6715b   
Genomic Coordinates chr10: 112299612 - 112299688
Description Homo sapiens miR-6715b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6715b-3p
Sequence 46| CUCAAACCGGCUGUGCCUGUGG |67
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs761643095 7 dbSNP
rs768295556 8 dbSNP
rs182337914 9 dbSNP
rs1369684979 11 dbSNP
rs776704371 13 dbSNP
rs1039819520 15 dbSNP
rs771110697 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SNRNP48   
Synonyms C6orf151, dJ336K20B.1, dJ512B11.2
Description small nuclear ribonucleoprotein U11/U12 subunit 48
Transcript NM_152551   
Expression
Putative miRNA Targets on SNRNP48
3'UTR of SNRNP48
(miRNA target sites are highlighted)		 
>SNRNP48|NM_152551|3'UTR
   1 ATGAAGTACTTGTACCTATATTAATTATGCTTACGCCATGATAACCAATATACAGATATATTAATTGGAATTCCTTTGCA
  81 TAGGAGAATGTTTTTATGATCTGTTTAGTGCTTATTATTTTTTTTATGATCTGTTTAGTGCTTATTATTTTCCAGTAAAT
 161 ATGCTTCAAACCATGAGTACACTATTAGGCCCTACAACTTTGTTTTCCTTATATTTTATTAGATGATTTGCTTCCTATAA
 241 CTGATGTTGTTTTGTTCGTTTTGCTAATATATGTATCTCAAAATTCTTTAAGTCAATATTTATCATATGTAAATTAAACA
 321 TGAATACATTCTCATCTTATAACTACATCTTATAAATAAGGCTAATAACCCTTAGAACACCACCTGCGGTTCTGTCCTCA
 401 CCCCAGTGGTGACTACTGTTTACCACTACACTGGTGAATTGTAGTAGGGAAAAACAATCTAAATATTGAAGAGGAATGGC
 481 CTAATTAAAATATGATGTAGTCATAGGATAGATTATTGTATTGGAGTTAAAAGAAATAATCTAGATCCATATTAACCTGG
 561 ATTGGTCTCAAAAACATAATGCTCAGTGAAAATAGCAAGTTGTAGAAAGTTATATACAAATTATATATATGTACAAAACA
 641 ATACTATGCATTCTCTATGGCTATATAATGTACGTAAATCTATTTTTAAAGGTTCAGAGGAATCCATACCAAAGTTCTAA
 721 CAGCGAGTAGGAGGTATAGATGAGAGATTAGGGGTGCAAATCAGGATTGGGAGGGTGGTCAGAGGGAACTTTAGCTTTAT
 801 CCATAACATTAATTTTTTTAAAAAATAAGGTCTTAATGTTTCATTTAATTTAAAATATACTGTCATGTTGTGTTTTGTAA
 881 ATCAACTGAATTGAGGTACTATTTACTTAGATTTATTGCACCCTTTTTACGTGTGTATTTTATTGGGTTTTGACAGATTC
 961 ATACCTCTGTGCAGCCACTATCACGATCAAGATACAAATATTTTCATTGCCCCCAAAATTCTCATACCCCCTTTCCCAAT
1041 CAATTCCTCTACCCCTAGCCCTAGGCAGCCACAGATTTGCTTTTGGTTACCGATTAGATCTATCCATTGTAGAATTCATG
1121 TAAATAGAATACTGTAGTATGTACTTTGCCTTCTTCCTCTCTGCAGATTTTTGAGATTGATCCCTGTGTGTCAGTTGTGC
1201 ATTTTTTTTGTTGCTGAGTAGTATGTTCTATCTTATGTCAGATCATTCACGTGAGACTTTGGCATGAAATGTTAAGCATC
1281 CGACATCTAAATAGCAATATTTTGAATACTGGAAACTCAGGTTAAAGATTTTGTTTCCAAGTAGAAATGAAATCTTATTA
1361 TTTTAATAAGTAGCTGACAGTGACAGAAAGATTGGATTTGGATCAGATTGGCTGTTAGGCTTCAGGTATGGGAAACAGCT
1441 CTCAGATTTATAAATTGGAAATCACCAGGTTACTTGCCAATATATAGTCATATTGCTGCCATTGTACTTAATTTCTAAAT
1521 ATATAAAATCCACATTTAAAAATTATAAAAGCAAGGACTTGGGAGTGACTGATGAATCATGAAATTGCTGCTTTTATAGA
1601 TCAAAACTACTTGAATCATCAGGAATTTCATATTTTTCATATTGTGTGACAACTTATAATTTTGTTTCAAATTGTGATTT
1681 CATTGATTTTACTAACTGGAAGGAAGAAGAGTAAAATTGGCATATTTAGGTTTTTTGTAGAAGAAAGATACAAGTGAAAA
1761 TTAGGAGTGGATTGGAGAAATTGGGGGGAAATAGAAGAGTACGGAGAAAGGAAGAGATTGAAAATGTTACCAGAGTTCTT
1841 TAAAGCTCACATTTTATAGTATCACTGCTACAAACTATTTAATGAAATGTGGCATCGGGTGAAAAGAGGCATTTGTTTGA
1921 TCCTTGAACGAATTAATCTCACGTACTTCCCTGTTTGTGGTTTGAGCCTTTCACTGGATGTGAGCTACTTGAGAGCAGGG
2001 TTTATGCCTTCATCAGCGTGACCCCTGTGCCTGCAGCCTCATAGGTGTTAATCTGTAATTTTAAATTTTGACAAAAGCAT
2081 TTTCACAGCCCTGCCACATAAGATCTAGTTTTTATTTCTAGAGTGCTGCTATGAATAATTACTATAGCTGCTGTCCATCT
2161 TGCCCATCCATTAAGGTACCTTCTCACAAACATTTCTAATCTACTGGCTGGAGTGCAGTGGTGCAGTCTGTAGCTCACTG
2241 CAGCCTCAAACTCCTAGGCTCAGGCGATCCTCTTGCCCTGGCCTCCCATGTAGCTGCAACTATAGGTGTGTGCCACTACA
2321 CCTGGCTAATGTTTTTAGTTTTTTAGAGATGGAGTCTTGCTCTGTTGCCTAGGCTGGTCTTGAACTCCTGGGCTCAGATG
2401 ATCCTCCTGTCCTCAGCCTCCCAAAATGCTGGGAGCCACCAGGCACCAGGTGTGATCTACCACACCTGTCTAAAAAGTAT
2481 GTATTTTTAAATTTTTTTGTAGAGACAGGATCTCACTATGTTCTCCAGCTGGTCTCAAGCTCCTGGCCTCGGCCTCCTAA
2561 AGTGCTGGGATTACAAGTGTGAGCCACTGTGCCTAGTCACTTTAATTGAGATATTGGCAAGTCAACTGCCATGCAGAGCC
2641 CAGGGCACTGGTTATATTCAGTAGGAAACTGAACTCAGCACTCAGAATTTTAAATTAAATCAATGATCTTCAAGTATTTG
2721 CCACTTTCGAGTACAGCTAATTGGATAATCTCAAACCCTTTAGTGAAAATATCTTAAATGCATTGAGAATATTTTCTAAT
2801 TACCTGTGTATGCTACAGTACAGACATTAATTCTATAAACATGTTCATAGGTCTTCCCCCTCGCCCCGCCCGTCTTCTAA
2881 GGGCATTTTCTGTTTCTTTTTAGTGAGTTCATGAATGTTTAACGGTTCTGGCGCAAAGCTTTCTTGCATTCTGAGCATAA
2961 AAATAATAAAACCCACTTATATTTGCTTGAGTGTGTTTACAAGTCAATTTCCTTTTATGTAGCTTGCTTTTTCATTTGCT
3041 ATAATTGATCCTGCAGGTGTGTGAATTATTAAACTAACGCTCTTTTAAACCACA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gguGUCCGUGUCGG--------CCAAACUc 5'
             || |:||  ||        ||||||| 
Target 5' tctCACGTACTTCCCTGTTTGTGGTTTGAg 3'
 1937 - 1966 145.00 -16.00
2 
miRNA  3' gguGUCCGUGUCGGCCAAACUc 5'
             |||||||  | ||| ||| 
Target 5' cacCAGGCAC--CAGGTGTGAt 3'
 2437 - 2456 135.00 -15.50
3 
miRNA  3' ggUGUCCGUGUCGGCCAAACUc 5'
            | |||||   :: |||||| 
Target 5' aaAGAGGCA---TTTGTTTGAt 3'
 1903 - 1921 125.00 -10.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30120840 14 COSMIC
COSN31545394 16 COSMIC
COSN30488287 17 COSMIC
COSN30115618 36 COSMIC
COSN30487047 37 COSMIC
COSN30529186 42 COSMIC
COSN31579763 126 COSMIC
COSN17076210 259 COSMIC
COSN17815176 278 COSMIC
COSN17814381 305 COSMIC
COSN21769768 334 COSMIC
COSN17814304 337 COSMIC
COSN17814941 400 COSMIC
COSN29467202 690 COSMIC
COSN9807118 846 COSMIC
COSN20369301 931 COSMIC
COSN17815455 1006 COSMIC
COSN17814067 1042 COSMIC
COSN23336403 1093 COSMIC
COSN6332255 1709 COSMIC
COSN20102365 1819 COSMIC
COSN31778457 1893 COSMIC
COSN20102369 2026 COSMIC
COSN17814862 2054 COSMIC
COSN17816096 2380 COSMIC
COSN17815441 2404 COSMIC
COSN17813856 2458 COSMIC
COSN22111228 2524 COSMIC
COSN5637060 2781 COSMIC
COSN15951729 3000 COSMIC
COSN15953039 3000 COSMIC
COSN16324393 3069 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1035903478 4 dbSNP
rs766064206 9 dbSNP
rs1535434 12 dbSNP
rs777052194 13 dbSNP
rs1222242883 15 dbSNP
rs1286517403 17 dbSNP
rs1174568582 21 dbSNP
rs1477129648 22 dbSNP
rs1317582960 26 dbSNP
rs762330050 28 dbSNP
rs1271751254 29 dbSNP
rs776421206 31 dbSNP
rs7450372 35 dbSNP
rs750792178 36 dbSNP
rs1469369108 37 dbSNP
rs1175104329 39 dbSNP
rs763246882 53 dbSNP
rs979222601 56 dbSNP
rs924996398 61 dbSNP
rs1411155054 72 dbSNP
rs1300844034 82 dbSNP
rs966655151 84 dbSNP
rs556036317 90 dbSNP
rs1366523894 91 dbSNP
rs1387101342 97 dbSNP
rs1282479162 98 dbSNP
rs1400352642 99 dbSNP
rs1342346149 112 dbSNP
rs577907878 113 dbSNP
rs985086750 116 dbSNP
rs769091917 117 dbSNP
rs925151552 118 dbSNP
rs541364895 119 dbSNP
rs943930018 127 dbSNP
rs1424687152 129 dbSNP
rs1171886817 137 dbSNP
rs1479017702 142 dbSNP
rs747053762 144 dbSNP
rs1193577173 146 dbSNP
rs1483833381 161 dbSNP
rs769746543 162 dbSNP
rs553886798 163 dbSNP
rs1211617597 175 dbSNP
rs1237736582 186 dbSNP
rs572170653 187 dbSNP
rs41302887 191 dbSNP
rs193248865 196 dbSNP
rs905915658 206 dbSNP
rs1193276269 208 dbSNP
rs1001528123 209 dbSNP
rs1379800070 210 dbSNP
rs141176884 212 dbSNP
rs902059012 214 dbSNP
rs1358595177 222 dbSNP
rs929588252 225 dbSNP
rs1467314814 227 dbSNP
rs896099199 238 dbSNP
rs887934535 240 dbSNP
rs1010468785 245 dbSNP
rs1416556635 249 dbSNP
rs1183151652 254 dbSNP
rs185703876 255 dbSNP
rs968926499 258 dbSNP
rs1348932994 259 dbSNP
rs564355997 271 dbSNP
rs1033381703 287 dbSNP
rs532791268 290 dbSNP
rs547794940 297 dbSNP
rs1032096926 300 dbSNP
rs1314793048 303 dbSNP
rs953775583 306 dbSNP
rs577935345 309 dbSNP
rs985159844 314 dbSNP
rs748576998 316 dbSNP
rs749195381 317 dbSNP
rs41302889 334 dbSNP
rs894937058 334 dbSNP
rs1013166220 337 dbSNP
rs761372584 339 dbSNP
rs1434122931 341 dbSNP
rs1298217734 348 dbSNP
rs1458718633 356 dbSNP
rs1367319095 376 dbSNP
rs566227714 379 dbSNP
rs1163330226 381 dbSNP
rs972696841 388 dbSNP
rs770701686 389 dbSNP
rs931162100 405 dbSNP
rs1048698878 409 dbSNP
rs1539537 411 dbSNP
rs1322425703 412 dbSNP
rs1032695603 416 dbSNP
rs1266915481 417 dbSNP
rs1259218226 426 dbSNP
rs1219293584 434 dbSNP
rs957851415 442 dbSNP
rs1286918842 445 dbSNP
rs937411998 448 dbSNP
rs1375024661 460 dbSNP
rs1057083324 480 dbSNP
rs985331556 481 dbSNP
rs895838960 498 dbSNP
rs1387526052 509 dbSNP
rs1010623936 512 dbSNP
rs759119815 513 dbSNP
rs144976693 529 dbSNP
rs1292092917 543 dbSNP
rs1404944545 544 dbSNP
rs1250407403 545 dbSNP
rs569861070 549 dbSNP
rs1158776241 553 dbSNP
rs1181198789 557 dbSNP
rs775168151 558 dbSNP
rs1000409860 559 dbSNP
rs1377898925 563 dbSNP
rs553016056 564 dbSNP
rs1029158878 567 dbSNP
rs953806422 572 dbSNP
rs1490178600 576 dbSNP
rs867006754 576 dbSNP
rs1166418562 583 dbSNP
rs923316565 589 dbSNP
rs151118523 602 dbSNP
rs1456482859 606 dbSNP
rs1321056027 609 dbSNP
rs1390729826 621 dbSNP
rs1047964145 622 dbSNP
rs763206782 622 dbSNP
rs965088691 628 dbSNP
rs942199559 631 dbSNP
rs1299691139 643 dbSNP
rs1404696764 645 dbSNP
rs972769173 647 dbSNP
rs1055222870 648 dbSNP
rs894864881 649 dbSNP
rs1382153544 658 dbSNP
rs1287765018 660 dbSNP
rs918548526 665 dbSNP
rs952729189 668 dbSNP
rs1305101708 671 dbSNP
rs190664839 674 dbSNP
rs570762370 679 dbSNP
rs1261202537 684 dbSNP
rs777316458 691 dbSNP
rs1484387331 692 dbSNP
rs1006697321 694 dbSNP
rs1460270004 699 dbSNP
rs1223090548 701 dbSNP
rs1057158244 709 dbSNP
rs1209949994 722 dbSNP
rs1217396030 724 dbSNP
rs1018133639 725 dbSNP
rs917297899 726 dbSNP
rs946071794 743 dbSNP
rs1238587928 746 dbSNP
rs964768630 750 dbSNP
rs1042108460 765 dbSNP
rs1483278904 767 dbSNP
rs1403660095 772 dbSNP
rs1334320747 785 dbSNP
rs1468908110 787 dbSNP
rs1400783899 790 dbSNP
rs1412865233 790 dbSNP
rs1172541636 793 dbSNP
rs1474425848 804 dbSNP
rs1183138639 806 dbSNP
rs904808273 807 dbSNP
rs1188104948 808 dbSNP
rs1000844132 813 dbSNP
rs140855940 813 dbSNP
rs923380678 820 dbSNP
rs976176682 820 dbSNP
rs1472093815 821 dbSNP
rs1260467098 831 dbSNP
rs1197104485 839 dbSNP
rs762376772 839 dbSNP
rs1159466381 843 dbSNP
rs1339365473 847 dbSNP
rs950738102 848 dbSNP
rs1247575742 849 dbSNP
rs1050608489 853 dbSNP
rs181490042 854 dbSNP
rs1451543833 855 dbSNP
rs909425050 858 dbSNP
rs1009042961 859 dbSNP
rs1408020881 865 dbSNP
rs1450255992 866 dbSNP
rs1296588664 874 dbSNP
rs1163772270 875 dbSNP
rs1350085157 878 dbSNP
rs553797756 881 dbSNP
rs1383530184 883 dbSNP
rs1183057477 902 dbSNP
rs1019384413 906 dbSNP
rs916766012 907 dbSNP
rs572190629 911 dbSNP
rs1437646478 928 dbSNP
rs2757598 931 dbSNP
rs1025717486 932 dbSNP
rs1244563286 938 dbSNP
rs1279917641 941 dbSNP
rs1353735642 944 dbSNP
rs185384179 948 dbSNP
rs1211603086 955 dbSNP
rs1439482477 957 dbSNP
rs766540129 958 dbSNP
rs141078418 961 dbSNP
rs1388514196 963 dbSNP
rs1363602329 965 dbSNP
rs958540078 973 dbSNP
rs1420409825 979 dbSNP
rs1382206992 981 dbSNP
rs893699022 985 dbSNP
rs992581742 986 dbSNP
rs1247720069 989 dbSNP
rs543554211 1002 dbSNP
rs77700971 1007 dbSNP
rs1268775813 1010 dbSNP
rs1217937809 1011 dbSNP
rs1253557514 1012 dbSNP
rs946117062 1013 dbSNP
rs1221767156 1020 dbSNP
rs965195975 1029 dbSNP
rs867735140 1032 dbSNP
rs796798772 1034 dbSNP
rs1171820421 1036 dbSNP
rs1302508281 1038 dbSNP
rs1400463494 1044 dbSNP
rs1362554699 1047 dbSNP
rs1316300257 1048 dbSNP
rs1400417611 1050 dbSNP
rs1425775325 1052 dbSNP
rs925929202 1054 dbSNP
rs1168245999 1056 dbSNP
rs935995531 1057 dbSNP
rs950862638 1058 dbSNP
rs1369953625 1064 dbSNP
rs1428945238 1066 dbSNP
rs1050681306 1067 dbSNP
rs755092962 1072 dbSNP
rs889340628 1075 dbSNP
rs1212996107 1079 dbSNP
rs1446115927 1085 dbSNP
rs1009107278 1086 dbSNP
rs1040554158 1090 dbSNP
rs1205133095 1092 dbSNP
rs1278916456 1092 dbSNP
rs983435301 1093 dbSNP
rs1410546550 1100 dbSNP
rs370990360 1101 dbSNP
rs900948209 1119 dbSNP
rs1343917540 1123 dbSNP
rs1436201749 1137 dbSNP
rs188549910 1144 dbSNP
rs781247958 1145 dbSNP
rs1359767288 1150 dbSNP
rs541692294 1152 dbSNP
rs1347598040 1154 dbSNP
rs952495397 1157 dbSNP
rs1468374292 1159 dbSNP
rs559820554 1160 dbSNP
rs1213260379 1176 dbSNP
rs1027952924 1177 dbSNP
rs991013232 1186 dbSNP
rs1034232504 1190 dbSNP
rs1417962959 1202 dbSNP
rs916857974 1202 dbSNP
rs958613317 1204 dbSNP
rs992654877 1213 dbSNP
rs1276291101 1216 dbSNP
rs530311394 1224 dbSNP
rs1237488711 1230 dbSNP
rs1185068023 1231 dbSNP
rs949571057 1234 dbSNP
rs1199012249 1237 dbSNP
rs749419898 1244 dbSNP
rs1047005564 1245 dbSNP
rs1197887932 1249 dbSNP
rs867018081 1251 dbSNP
rs17339296 1252 dbSNP
rs1379997440 1270 dbSNP
rs1317229970 1272 dbSNP
rs1450809802 1277 dbSNP
rs1186550642 1280 dbSNP
rs1332521489 1282 dbSNP
rs569924191 1283 dbSNP
rs1353077855 1286 dbSNP
rs150250166 1306 dbSNP
rs552276028 1307 dbSNP
rs1053435322 1311 dbSNP
rs1413963296 1317 dbSNP
rs1184899418 1328 dbSNP
rs181389875 1329 dbSNP
rs935996938 1339 dbSNP
rs1242124929 1341 dbSNP
rs1178816297 1342 dbSNP
rs893460239 1343 dbSNP
rs1230903331 1353 dbSNP
rs534742265 1355 dbSNP
rs1203800169 1366 dbSNP
rs910838782 1370 dbSNP
rs2806218 1381 dbSNP
rs1243842986 1385 dbSNP
rs1358756372 1385 dbSNP
rs901128748 1396 dbSNP
rs1393294443 1399 dbSNP
rs1371651101 1407 dbSNP
rs565884428 1409 dbSNP
rs536443772 1412 dbSNP
rs929460853 1415 dbSNP
rs1333152854 1420 dbSNP
rs138906484 1422 dbSNP
rs1047259241 1429 dbSNP
rs888163825 1432 dbSNP
rs1297486148 1446 dbSNP
rs576309320 1451 dbSNP
rs1384038524 1455 dbSNP
rs1228485729 1456 dbSNP
rs1158884755 1463 dbSNP
rs1299243638 1467 dbSNP
rs745631563 1469 dbSNP
rs1353656931 1481 dbSNP
rs1420487251 1487 dbSNP
rs1033969179 1488 dbSNP
rs894426677 1490 dbSNP
rs148976933 1497 dbSNP
rs1176376105 1507 dbSNP
rs558399999 1520 dbSNP
rs1270989547 1525 dbSNP
rs1220105566 1531 dbSNP
rs1453064596 1542 dbSNP
rs1206642373 1547 dbSNP
rs1024203147 1552 dbSNP
rs967631725 1555 dbSNP
rs1490208039 1575 dbSNP
rs977250337 1580 dbSNP
rs1450072184 1594 dbSNP
rs1190451215 1596 dbSNP
rs1005395670 1600 dbSNP
rs1306786817 1607 dbSNP
rs1220160166 1609 dbSNP
rs1347724486 1621 dbSNP
rs1301874172 1624 dbSNP
rs1404810398 1627 dbSNP
rs1472529352 1631 dbSNP
rs1033515816 1638 dbSNP
rs957432093 1640 dbSNP
rs775328274 1643 dbSNP
rs963335152 1645 dbSNP
rs1157852577 1657 dbSNP
rs990813604 1658 dbSNP
rs1431069200 1660 dbSNP
rs1023804411 1669 dbSNP
rs1389996099 1671 dbSNP
rs971395935 1684 dbSNP
rs1206941920 1687 dbSNP
rs1485045955 1695 dbSNP
rs62388102 1700 dbSNP
rs1313556545 1704 dbSNP
rs1260388932 1710 dbSNP
rs1044764 1712 dbSNP
rs910534843 1720 dbSNP
rs1281755421 1727 dbSNP
rs935540055 1731 dbSNP
rs1341643671 1732 dbSNP
rs1284401187 1735 dbSNP
rs944664519 1738 dbSNP
rs1226332757 1739 dbSNP
rs976753247 1739 dbSNP
rs919481676 1747 dbSNP
rs942342260 1749 dbSNP
rs1465188497 1750 dbSNP
rs1210470806 1766 dbSNP
rs929466234 1768 dbSNP
rs1408103451 1783 dbSNP
rs371049493 1787 dbSNP
rs1441898265 1788 dbSNP
rs901054124 1789 dbSNP
rs559986722 1800 dbSNP
rs1261051618 1802 dbSNP
rs574750231 1803 dbSNP
rs542119070 1804 dbSNP
rs1055412261 1807 dbSNP
rs1261703429 1815 dbSNP
rs66604210 1817 dbSNP
rs71641689 1817 dbSNP
rs749323375 1817 dbSNP
rs768347587 1818 dbSNP
rs201866260 1828 dbSNP
rs200335855 1829 dbSNP
rs1046867922 1831 dbSNP
rs886924128 1834 dbSNP
rs1294215778 1837 dbSNP
rs1013847708 1842 dbSNP
rs1301552314 1856 dbSNP
rs1024651959 1857 dbSNP
rs903063703 1862 dbSNP
rs1005413132 1878 dbSNP
rs999136069 1884 dbSNP
rs185230707 1885 dbSNP
rs1396896461 1888 dbSNP
rs190039964 1897 dbSNP
rs899294746 1900 dbSNP
rs34167194 1902 dbSNP
rs1460353909 1903 dbSNP
rs957463349 1904 dbSNP
rs1007664525 1910 dbSNP
rs1446721861 1910 dbSNP
rs1017671749 1911 dbSNP
rs1023606329 1920 dbSNP
rs966040940 1931 dbSNP
rs182359296 1932 dbSNP
rs982754085 1941 dbSNP
rs1339300973 1942 dbSNP
rs564451712 1943 dbSNP
rs1031282257 1944 dbSNP
rs528486649 1946 dbSNP
rs187016909 1947 dbSNP
rs1230058868 1948 dbSNP
rs1451379965 1954 dbSNP
rs1246968271 1963 dbSNP
rs1044767 1964 dbSNP
rs1344309896 1966 dbSNP
rs942432323 1969 dbSNP
rs760379465 1975 dbSNP
rs1395652527 1976 dbSNP
rs1201091735 1979 dbSNP
rs1426655671 1985 dbSNP
rs536506862 1990 dbSNP
rs145733713 1998 dbSNP
rs1482116024 1999 dbSNP
rs933694986 2000 dbSNP
rs138314912 2004 dbSNP
rs1270265179 2012 dbSNP
rs41302891 2013 dbSNP
rs1490699380 2018 dbSNP
rs1038176103 2019 dbSNP
rs200751993 2021 dbSNP
rs10717454 2022 dbSNP
rs796361220 2022 dbSNP
rs1350899145 2027 dbSNP
rs1174446661 2038 dbSNP
rs1236639245 2045 dbSNP
rs1377553571 2050 dbSNP
rs1303691140 2078 dbSNP
rs1466953104 2079 dbSNP
rs949757556 2088 dbSNP
rs1363852274 2089 dbSNP
rs1302621899 2090 dbSNP
rs1012304889 2092 dbSNP
rs1174833102 2103 dbSNP
rs1045401760 2106 dbSNP
rs906516341 2110 dbSNP
rs1003583202 2125 dbSNP
rs1307003665 2127 dbSNP
rs1430341823 2132 dbSNP
rs1350773705 2142 dbSNP
rs773473921 2150 dbSNP
rs1392918809 2152 dbSNP
rs879539649 2155 dbSNP
rs1479737697 2161 dbSNP
rs1266237760 2164 dbSNP
rs1299002872 2166 dbSNP
rs1220153974 2167 dbSNP
rs543206828 2171 dbSNP
rs1447025183 2179 dbSNP
rs763426753 2181 dbSNP
rs1202928446 2190 dbSNP
rs1328238769 2195 dbSNP
rs903124847 2196 dbSNP
rs1225347441 2198 dbSNP
rs766701373 2199 dbSNP
rs998762153 2202 dbSNP
rs576904374 2205 dbSNP
rs1330309908 2210 dbSNP
rs1328236340 2211 dbSNP
rs1412423034 2213 dbSNP
rs1316507339 2215 dbSNP
rs1400285375 2228 dbSNP
rs1054348059 2235 dbSNP
rs1407379723 2241 dbSNP
rs1031670508 2247 dbSNP
rs2806217 2250 dbSNP
rs755183113 2252 dbSNP
rs1017711017 2255 dbSNP
rs1190649165 2259 dbSNP
rs966110380 2260 dbSNP
rs1464157986 2265 dbSNP
rs1263573292 2266 dbSNP
rs61336291 2267 dbSNP
rs1215022593 2271 dbSNP
rs963764990 2275 dbSNP
rs574116422 2298 dbSNP
rs542084282 2300 dbSNP
rs1430368042 2301 dbSNP
rs975139366 2301 dbSNP
rs1484197522 2303 dbSNP
rs1383765651 2311 dbSNP
rs563674771 2318 dbSNP
rs951063536 2322 dbSNP
rs1450948167 2325 dbSNP
rs1405721497 2326 dbSNP
rs142775421 2332 dbSNP
rs1412116757 2340 dbSNP
rs1421103925 2349 dbSNP
rs1165618484 2350 dbSNP
rs1189828616 2355 dbSNP
rs1243399116 2360 dbSNP
rs749884391 2368 dbSNP
rs909444251 2372 dbSNP
rs546128163 2375 dbSNP
rs564597427 2376 dbSNP
rs922405102 2402 dbSNP
rs1267031476 2403 dbSNP
rs1434150603 2407 dbSNP
rs1201585861 2409 dbSNP
rs959533934 2423 dbSNP
rs990913206 2433 dbSNP
rs778858179 2453 dbSNP
rs1309185148 2455 dbSNP
rs915693427 2463 dbSNP
rs949824532 2464 dbSNP
rs1360202443 2466 dbSNP
rs1317429769 2468 dbSNP
rs1243976258 2470 dbSNP
rs1378973740 2471 dbSNP
rs1299095687 2472 dbSNP
rs982508238 2473 dbSNP
rs1353246694 2484 dbSNP
rs1328714232 2489 dbSNP
rs528540029 2492 dbSNP
rs908414904 2500 dbSNP
rs370139376 2501 dbSNP
rs1385243444 2505 dbSNP
rs1038145852 2507 dbSNP
rs1442382117 2508 dbSNP
rs924315971 2511 dbSNP
rs1412888554 2526 dbSNP
rs146050206 2533 dbSNP
rs1481606766 2535 dbSNP
rs934299417 2537 dbSNP
rs915726291 2539 dbSNP
rs948585102 2551 dbSNP
rs1490537201 2552 dbSNP
rs1054377899 2560 dbSNP
rs1220620662 2563 dbSNP
rs1045550796 2575 dbSNP
rs893026166 2579 dbSNP
rs374343525 2584 dbSNP
rs943218264 2589 dbSNP
rs1038884391 2590 dbSNP
rs901947744 2594 dbSNP
rs1003916452 2597 dbSNP
rs1288276046 2606 dbSNP
rs760131474 2608 dbSNP
rs1406029283 2616 dbSNP
rs1052452994 2619 dbSNP
rs562037385 2620 dbSNP
rs1304431025 2621 dbSNP
rs1456107168 2632 dbSNP
rs1389695183 2643 dbSNP
rs529338209 2644 dbSNP
rs997597540 2648 dbSNP
rs1420655639 2661 dbSNP
rs767907376 2664 dbSNP
rs41302893 2665 dbSNP
rs1011179218 2666 dbSNP
rs1480719165 2666 dbSNP
rs554897309 2686 dbSNP
rs1220321595 2693 dbSNP
rs964194056 2697 dbSNP
rs1006137239 2704 dbSNP
rs997051900 2709 dbSNP
rs1016477408 2712 dbSNP
rs1267879616 2714 dbSNP
rs959605647 2729 dbSNP
rs990985296 2730 dbSNP
rs758306325 2735 dbSNP
rs779990303 2742 dbSNP
rs1366202341 2744 dbSNP
rs1289096069 2751 dbSNP
rs1455007551 2755 dbSNP
rs1386267433 2756 dbSNP
rs1158101474 2757 dbSNP
rs1470290028 2758 dbSNP
rs1197139761 2760 dbSNP
rs76573010 2761 dbSNP
rs971276676 2763 dbSNP
rs572019171 2774 dbSNP
rs962377700 2782 dbSNP
rs1247843808 2788 dbSNP
rs1204692103 2790 dbSNP
rs981234182 2799 dbSNP
rs973948564 2804 dbSNP
rs1219599428 2807 dbSNP
rs78382609 2812 dbSNP
rs1488999833 2817 dbSNP
rs1295664449 2825 dbSNP
rs948555784 2826 dbSNP
rs1362550651 2836 dbSNP
rs1319410973 2842 dbSNP
rs981302577 2844 dbSNP
rs1407940795 2849 dbSNP
rs1170758909 2854 dbSNP
rs116102204 2855 dbSNP
rs989808509 2863 dbSNP
rs914532618 2864 dbSNP
rs1449456083 2866 dbSNP
rs1189793061 2868 dbSNP
rs534391056 2869 dbSNP
rs1184402939 2871 dbSNP
rs553049120 2872 dbSNP
rs1038915507 2873 dbSNP
rs146960918 2887 dbSNP
rs4212 2887 dbSNP
rs57510733 2887 dbSNP
rs1251445748 2906 dbSNP
rs1458190950 2908 dbSNP
rs901688961 2911 dbSNP
rs933125237 2924 dbSNP
rs1044761 2933 dbSNP
rs1384783285 2940 dbSNP
rs1434204586 2947 dbSNP
rs886487505 2958 dbSNP
rs1395448706 2971 dbSNP
rs192383425 2980 dbSNP
rs1299752566 2981 dbSNP
rs1427902486 2983 dbSNP
rs1389585140 2991 dbSNP
rs1016213768 3001 dbSNP
rs1164507063 3008 dbSNP
rs1446640400 3014 dbSNP
rs1367158574 3017 dbSNP
rs1364111001 3022 dbSNP
rs1029838214 3042 dbSNP
rs1226731824 3043 dbSNP
rs1253294375 3043 dbSNP
rs895424026 3045 dbSNP
rs1312244245 3049 dbSNP
rs890846829 3051 dbSNP
rs1322625781 3058 dbSNP
rs1222821649 3064 dbSNP
rs141802924 3079 dbSNP
rs150585679 3080 dbSNP
rs962346629 3081 dbSNP
rs1336055981 3083 dbSNP
rs1025626190 3087 dbSNP
rs115197614 3090 dbSNP
rs1370076839 3093 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 154007.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000342415.5 | 3UTR | AGCCUUUCACUGGAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
75 hsa-miR-6715b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080245 SMAD4 SMAD family member 4 2 2
MIRT142553 TNRC6A trinucleotide repeat containing 6A 2 4
MIRT384667 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT446660 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT463754 YTHDC1 YTH domain containing 1 2 2
MIRT476873 FEM1B fem-1 homolog B 2 2
MIRT478429 DAZAP2 DAZ associated protein 2 2 2
MIRT495237 SPRY3 sprouty RTK signaling antagonist 3 2 4
MIRT495945 ANKRD52 ankyrin repeat domain 52 2 2
MIRT497116 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT497344 RPP25L ribonuclease P/MRP subunit p25 like 2 2
MIRT498133 KLHL3 kelch like family member 3 2 2
MIRT502306 GNA13 G protein subunit alpha 13 2 2
MIRT510854 RAN RAN, member RAS oncogene family 2 8
MIRT513323 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 6
MIRT523995 DTX4 deltex E3 ubiquitin ligase 4 2 4
MIRT525837 FAR2 fatty acyl-CoA reductase 2 2 2
MIRT527506 MYD88 myeloid differentiation primary response 88 2 2
MIRT527668 CIT citron rho-interacting serine/threonine kinase 2 2
MIRT527996 NDNF neuron derived neurotrophic factor 2 2
MIRT528052 MRS2 MRS2, magnesium transporter 2 2
MIRT528257 GPRIN2 G protein regulated inducer of neurite outgrowth 2 2 2
MIRT529401 ICK intestinal cell kinase 2 2
MIRT529558 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT530323 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT532230 KLF2 Kruppel like factor 2 2 2
MIRT534220 SLC35G1 solute carrier family 35 member G1 2 2
MIRT536195 MAML2 mastermind like transcriptional coactivator 2 2 2
MIRT538093 DEPDC1 DEP domain containing 1 2 2
MIRT543159 GTF2A1 general transcription factor IIA subunit 1 2 2
MIRT545840 ZNF264 zinc finger protein 264 2 4
MIRT546401 SRP9 signal recognition particle 9 2 2
MIRT550643 SLC39A7 solute carrier family 39 member 7 2 2
MIRT558648 CNKSR3 CNKSR family member 3 2 2
MIRT562208 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT562886 NACA2 nascent polypeptide associated complex alpha subunit 2 2 2
MIRT566786 MKL2 MKL1/myocardin like 2 2 2
MIRT567508 FOXC1 forkhead box C1 2 2
MIRT570235 CPNE5 copine 5 2 2
MIRT576823 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT610704 GPX6 glutathione peroxidase 6 2 2
MIRT611141 CRISP1 cysteine rich secretory protein 1 2 4
MIRT618100 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT619086 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT619716 FCF1 FCF1, rRNA-processing protein 2 2
MIRT620953 POLR2D RNA polymerase II subunit D 2 2
MIRT624645 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT624655 ARMC10 armadillo repeat containing 10 2 2
MIRT630778 KLHL42 kelch like family member 42 2 4
MIRT635596 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT637122 MKX mohawk homeobox 2 2
MIRT645527 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT647249 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT651508 WNT9A Wnt family member 9A 2 2
MIRT658721 ELK4 ELK4, ETS transcription factor 2 2
MIRT658804 EFNA5 ephrin A5 2 2
MIRT659319 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT664605 UGT3A1 UDP glycosyltransferase family 3 member A1 2 2
MIRT666047 STON2 stonin 2 2 2
MIRT672228 PDE7B phosphodiesterase 7B 2 2
MIRT683243 WFDC6 WAP four-disulfide core domain 6 2 2
MIRT686565 TPM3 tropomyosin 3 2 2
MIRT697560 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT699294 SLC5A3 solute carrier family 5 member 3 2 2
MIRT707134 TRA2B transformer 2 beta homolog 2 2
MIRT712255 PTPRN2 protein tyrosine phosphatase, receptor type N2 2 2
MIRT713896 IGF2R insulin like growth factor 2 receptor 2 2
MIRT716186 UBN2 ubinuclein 2 2 2
MIRT716525 KSR2 kinase suppressor of ras 2 2 2
MIRT716968 CNOT6 CCR4-NOT transcription complex subunit 6 2 2
MIRT717154 LRRC3C leucine rich repeat containing 3C 2 2
MIRT718669 LSM10 LSM10, U7 small nuclear RNA associated 2 2
MIRT722100 PTBP3 polypyrimidine tract binding protein 3 2 2
MIRT723569 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT724703 CRAMP1L cramped chromatin regulator homolog 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6715b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-6715b-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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