miRTarBase - #MIRT530230


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pre-miRNA Information
pre-miRNA hsa-mir-4760   
Genomic Coordinates chr21: 40212352 - 40212431
Description Homo sapiens miR-4760 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4760-5p
Sequence 10| UUUAGAUUGAACAUGAAGUUAG |31
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1305812532 3 dbSNP
rs776241608 7 dbSNP
Putative Targets

Gene Information
Gene Symbol WSB2   
Synonyms SBA2
Description WD repeat and SOCS box containing 2
Transcript NM_018639   
Expression
Putative miRNA Targets on WSB2
3'UTR of WSB2
(miRNA target sites are highlighted)		 
>WSB2|NM_018639|3'UTR
   1 GCAACACCACATCTTGTGCTTCTTTGTAGCAGGGTAAATCGTCCTGTCAAAGGGAGTTGCTGGAATAATGGGCCAAACAT
  81 CTGGTCTTGCATTGAAATAGCATTTCTTTGGGATTGTGAATAGAATGTAGCAAAACCAGATTCCAGTGTACTAGTCATGG
 161 ATCTTTCTCTCCCTGGCATGTGAAAGTCAGTCTTAGAGGAAGAGATTCCACTTGCACGGCAACAGAGCCTTACGTTAAAT
 241 TTTCAGTCCAGTTATGAACAGCAAGTGTTGAACTCTTTCTGCTTGTTTTGATTCAAAGTGCAGTTACTGATGTTGTTTTG
 321 ATTATGCAACTAAGTAGGCCTCCAGAGCCTCTCTAGTGGCAGAGCAGCTCACACTCCCTCCGCTGGGAACGATGGCTTCT
 401 GCCTAGTACCTATCCTTGTGTTTCTGATGCAGTGGTAGCATTGGTTCAAGTTCTCTCCTGCTGTGGTCAGAGTTGCTTCG
 481 ATGTTGGCCAAGTGCTTTTCTTCTTGGGCTCCCTTCTGACCTGCAGGACAGTTTTCCTGGAGCCATTTGGTATGAGGTAT
 561 TAATTTAGCTTAACTAAATTACAGGGGACTCAGAGGCCGTGCTCCTGACCGATCCAGACACTATTACTGGCTTTTTTTTT
 641 TTTTTTTTAACAATGGTGTGCATGTGCAGGAAATGACAAATTTGTATGTCAGATTATACAAGGATGTATTCTTAAACCGC
 721 ATGACTATTCAGATGGCTACTGAGTTATCAGTGGCCATTTATTAGCATCATATTTATTTGTATTTTCTCAACAGATGTTA
 801 AGGTACAACTGTGTTTTTCTCGATTATCTAAAAACCATAGTACTTAAATTGAACAGTTGCAAAGATGTCTTAATTGTGTA
 881 AAGAATTGGTGTAGTCATGACTTTAGCTGATACTCTTATGTACGAGATCTGTCTCTGCTGTTTAACTTCATTGGATTAAT
 961 CAGCTGGTTTCAACTCTACTGCGAAACAAAAATAGCTCCTTAAAAGTACTGTTCTCCTTCAGTGGCATGTAGTTATCTAA
1041 TCAAGACACCTCATTCAAACAAAACCTGCCTTAGGAAAATTTAATATATTTTAAATTATTTTAAAAGAAATACAACATCT
1121 TATTCTTTAGCTTTCTTAATCGGTGCTTTATGGAGGCCAGTGTAACGTTACATGACTCGTTGAGAAAGTTGAGGAATTTC
1201 CTCTACCACCTTTGTTGCTTGAAGAAAAACATGTCTTTTCAAAATGAGAGGCTTTCATTGAAGAAAAGAAAAAAACAACA
1281 GTTAAAAGCTTTTGGCTCTCTGTTTCATTTTTTTCCATTAAGAAAAAAAAAAGTCCCCTTTTAAAACAAGCAGGGCTGGG
1361 TGTGACGGCACATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGACTGCTTGAGCCCAGGAGTTCAAGATCA
1441 GCCTGGGCAACAGAGTGAGATAAGACCCAATCTTTATTTAAAAAATAAATAAATAAATAGCCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gaUUGAAGUACA-AGUUAGAUUu 5'
            |::  |||||  : |||||| 
Target 5' tcAGTGGCATGTAGTTATCTAAt 3'
 1019 - 1041 124.00 -8.50
2 
miRNA  3' gaUUGAAGUACAA------GUUAGAUUu 5'
            |||| ::| ||      : |||||| 
Target 5' acAACTGTGTTTTTCTCGATTATCTAAa 3'
 805 - 832 122.00 -7.42
3 
miRNA  3' gaUUGAAGUA--CAAGUUAGauuu 5'
            ||||||||  | |:||||    
Target 5' ttAACTTCATTGGATTAATCagct 3'
 942 - 965 118.00 -10.26
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30148154 2 COSMIC
COSN30486270 4 COSMIC
COSN30499213 44 COSMIC
COSN30155262 54 COSMIC
COSN31586745 81 COSMIC
COSN31613270 84 COSMIC
COSN1143057 105 COSMIC
COSN5713016 168 COSMIC
COSN20077657 198 COSMIC
COSN6613405 332 COSMIC
COSN5932021 581 COSMIC
COSN27209253 632 COSMIC
COSN31548854 828 COSMIC
COSN31540312 894 COSMIC
COSN8585432 954 COSMIC
COSN27136450 958 COSMIC
COSN29097945 1322 COSMIC
COSN21968115 1339 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs781357348 2 dbSNP
rs150766658 4 dbSNP
rs751905390 6 dbSNP
rs780222378 7 dbSNP
rs1034671873 8 dbSNP
rs758947412 9 dbSNP
rs750852854 11 dbSNP
rs763682338 12 dbSNP
rs760239670 15 dbSNP
rs200618171 23 dbSNP
rs752466225 29 dbSNP
rs201888386 32 dbSNP
rs1214630064 36 dbSNP
rs759209052 40 dbSNP
rs368150064 41 dbSNP
rs1435972607 49 dbSNP
rs770594983 51 dbSNP
rs1224574340 55 dbSNP
rs1269546567 78 dbSNP
rs1490108626 79 dbSNP
rs1421951302 80 dbSNP
rs959679291 92 dbSNP
rs1376117343 106 dbSNP
rs758988539 108 dbSNP
rs1168537554 113 dbSNP
rs555881905 114 dbSNP
rs1244214424 118 dbSNP
rs1013689952 148 dbSNP
rs750783712 149 dbSNP
rs1305434991 157 dbSNP
rs1185959537 158 dbSNP
rs1404718737 161 dbSNP
rs765725340 165 dbSNP
rs1052609773 177 dbSNP
rs1001032612 179 dbSNP
rs536970955 180 dbSNP
rs1327804858 189 dbSNP
rs141381417 192 dbSNP
rs1269256733 199 dbSNP
rs1339383169 204 dbSNP
rs1040340170 206 dbSNP
rs1165647944 209 dbSNP
rs77542352 217 dbSNP
rs762077635 218 dbSNP
rs1205699475 219 dbSNP
rs767191250 228 dbSNP
rs1241761658 230 dbSNP
rs1050682741 233 dbSNP
rs534345652 234 dbSNP
rs10638 241 dbSNP
rs1161790461 243 dbSNP
rs551893733 247 dbSNP
rs1383145053 248 dbSNP
rs1225467464 254 dbSNP
rs181946603 256 dbSNP
rs962847595 259 dbSNP
rs1454114457 266 dbSNP
rs1315202981 298 dbSNP
rs1049680144 300 dbSNP
rs1242469554 308 dbSNP
rs1262446913 313 dbSNP
rs1351059502 318 dbSNP
rs927257676 319 dbSNP
rs1267742592 324 dbSNP
rs920145961 338 dbSNP
rs1315215045 339 dbSNP
rs914479209 345 dbSNP
rs980446881 347 dbSNP
rs971310487 358 dbSNP
rs1376932490 362 dbSNP
rs1454569440 372 dbSNP
rs1158420119 377 dbSNP
rs569263679 382 dbSNP
rs1470775380 385 dbSNP
rs760659162 390 dbSNP
rs773986149 391 dbSNP
rs1031086166 395 dbSNP
rs1238050611 396 dbSNP
rs1286283769 404 dbSNP
rs1327297679 416 dbSNP
rs1264011369 418 dbSNP
rs1482932422 427 dbSNP
rs1001063098 428 dbSNP
rs1306409553 431 dbSNP
rs1253279461 433 dbSNP
rs959731571 443 dbSNP
rs573079973 450 dbSNP
rs1034019457 461 dbSNP
rs529953998 464 dbSNP
rs767857335 464 dbSNP
rs1176633940 466 dbSNP
rs1404910375 468 dbSNP
rs1464103737 473 dbSNP
rs1299445800 474 dbSNP
rs904035798 479 dbSNP
rs189185249 480 dbSNP
rs1390785045 490 dbSNP
rs1306135617 497 dbSNP
rs554723911 504 dbSNP
rs891338917 511 dbSNP
rs1284084609 517 dbSNP
rs1311897622 521 dbSNP
rs371785935 523 dbSNP
rs1165596350 524 dbSNP
rs1253194319 526 dbSNP
rs1010101074 529 dbSNP
rs13649 538 dbSNP
rs1205014605 542 dbSNP
rs1050756695 549 dbSNP
rs1422541980 553 dbSNP
rs547192171 556 dbSNP
rs527439308 563 dbSNP
rs929635332 566 dbSNP
rs896937117 568 dbSNP
rs779507167 569 dbSNP
rs1424018250 570 dbSNP
rs1413732300 574 dbSNP
rs1178080676 581 dbSNP
rs1471366116 583 dbSNP
rs1171869695 585 dbSNP
rs1373108668 587 dbSNP
rs770744494 589 dbSNP
rs564920911 591 dbSNP
rs941097828 598 dbSNP
rs186203065 599 dbSNP
rs979926124 602 dbSNP
rs1302372840 609 dbSNP
rs1367143868 610 dbSNP
rs73217914 611 dbSNP
rs531283043 619 dbSNP
rs1291825274 620 dbSNP
rs1308095403 622 dbSNP
rs1224106922 623 dbSNP
rs1019696488 625 dbSNP
rs1319800260 626 dbSNP
rs1311939614 629 dbSNP
rs1224066487 630 dbSNP
rs1375250832 631 dbSNP
rs35299550 632 dbSNP
rs1362294260 634 dbSNP
rs76333372 634 dbSNP
rs1286288665 639 dbSNP
rs917170797 648 dbSNP
rs1166245608 649 dbSNP
rs1187852862 649 dbSNP
rs1290789580 649 dbSNP
rs1448279519 649 dbSNP
rs1487725621 649 dbSNP
rs549173254 649 dbSNP
rs796773753 649 dbSNP
rs878892697 649 dbSNP
rs1366464147 651 dbSNP
rs1295562239 653 dbSNP
rs1385582632 667 dbSNP
rs889836727 679 dbSNP
rs562499933 682 dbSNP
rs542608307 687 dbSNP
rs1030981931 697 dbSNP
rs1260940345 698 dbSNP
rs979936925 699 dbSNP
rs1464202677 705 dbSNP
rs1186097285 708 dbSNP
rs1244486248 713 dbSNP
rs1037674808 714 dbSNP
rs1181154544 718 dbSNP
rs940235762 719 dbSNP
rs772945289 721 dbSNP
rs1018859428 722 dbSNP
rs574392133 723 dbSNP
rs1007056451 732 dbSNP
rs1159642800 747 dbSNP
rs773652008 751 dbSNP
rs1389631141 755 dbSNP
rs1456955244 757 dbSNP
rs769593426 758 dbSNP
rs918084934 761 dbSNP
rs1056603836 787 dbSNP
rs938419814 807 dbSNP
rs375339533 809 dbSNP
rs1410188953 811 dbSNP
rs1181956528 812 dbSNP
rs927000645 815 dbSNP
rs979809608 815 dbSNP
rs747736569 821 dbSNP
rs968770791 822 dbSNP
rs1472036384 826 dbSNP
rs1208899408 836 dbSNP
rs1269176489 838 dbSNP
rs993817266 840 dbSNP
rs896845770 867 dbSNP
rs1192366775 886 dbSNP
rs11540134 887 dbSNP
rs1038013270 889 dbSNP
rs1410906386 890 dbSNP
rs1471503003 908 dbSNP
rs375468145 911 dbSNP
rs1157137556 914 dbSNP
rs914530500 919 dbSNP
rs989131930 920 dbSNP
rs1333656100 923 dbSNP
rs780707023 932 dbSNP
rs1445039981 933 dbSNP
rs941115636 936 dbSNP
rs1052926058 937 dbSNP
rs1350201052 940 dbSNP
rs771777990 942 dbSNP
rs1284802900 944 dbSNP
rs11540133 952 dbSNP
rs1345352771 958 dbSNP
rs554469013 960 dbSNP
rs905573734 969 dbSNP
rs1439079643 973 dbSNP
rs1019416867 982 dbSNP
rs1044662984 983 dbSNP
rs1007988821 987 dbSNP
rs11540135 998 dbSNP
rs1481910491 999 dbSNP
rs949857963 1008 dbSNP
rs1271298459 1011 dbSNP
rs1285436650 1014 dbSNP
rs180956807 1028 dbSNP
rs1366985212 1033 dbSNP
rs988744309 1036 dbSNP
rs1370554446 1041 dbSNP
rs898480300 1060 dbSNP
rs754713508 1080 dbSNP
rs934534047 1086 dbSNP
rs1305392636 1089 dbSNP
rs1433424672 1091 dbSNP
rs1289572547 1095 dbSNP
rs1037324075 1115 dbSNP
rs1272745282 1116 dbSNP
rs923943972 1132 dbSNP
rs1158820391 1133 dbSNP
rs578158454 1138 dbSNP
rs1340036050 1143 dbSNP
rs1224408231 1157 dbSNP
rs865774428 1158 dbSNP
rs1450851194 1166 dbSNP
rs911301857 1167 dbSNP
rs1245215631 1168 dbSNP
rs1476430365 1172 dbSNP
rs1177786122 1174 dbSNP
rs1431149688 1178 dbSNP
rs1266025482 1179 dbSNP
rs986060998 1185 dbSNP
rs955520463 1189 dbSNP
rs1186629066 1198 dbSNP
rs1391850599 1205 dbSNP
rs1405157929 1205 dbSNP
rs1321094931 1208 dbSNP
rs1029762292 1215 dbSNP
rs558048610 1216 dbSNP
rs994392659 1220 dbSNP
rs1327896567 1229 dbSNP
rs1044531294 1230 dbSNP
rs961574960 1231 dbSNP
rs1296291882 1234 dbSNP
rs1017014986 1235 dbSNP
rs1248031938 1236 dbSNP
rs1005217970 1252 dbSNP
rs905645065 1260 dbSNP
rs1355309190 1263 dbSNP
rs1207808161 1266 dbSNP
rs988461522 1268 dbSNP
rs1466458568 1276 dbSNP
rs148695294 1277 dbSNP
rs16948110 1279 dbSNP
rs1247447976 1281 dbSNP
rs1447753576 1285 dbSNP
rs1185900171 1296 dbSNP
rs1369550536 1299 dbSNP
rs1472674316 1301 dbSNP
rs912457837 1302 dbSNP
rs955972381 1302 dbSNP
rs1323994715 1315 dbSNP
rs1044141488 1326 dbSNP
rs147211979 1328 dbSNP
rs1339863684 1333 dbSNP
rs1454130865 1333 dbSNP
rs527845385 1333 dbSNP
rs1242310249 1335 dbSNP
rs1281109424 1338 dbSNP
rs1231312034 1343 dbSNP
rs1329641123 1343 dbSNP
rs1014121819 1366 dbSNP
rs370986997 1367 dbSNP
rs1384016444 1372 dbSNP
rs974559119 1376 dbSNP
rs1257470261 1384 dbSNP
rs189171282 1393 dbSNP
rs934565246 1396 dbSNP
rs1004186828 1410 dbSNP
rs925888786 1420 dbSNP
rs896758436 1424 dbSNP
rs1157884832 1426 dbSNP
rs1409317850 1433 dbSNP
rs558269699 1436 dbSNP
rs1408741292 1442 dbSNP
rs1302970181 1445 dbSNP
rs1401370846 1449 dbSNP
rs1394174263 1451 dbSNP
rs868709236 1460 dbSNP
rs774865158 1466 dbSNP
rs115747678 1470 dbSNP
rs947132491 1472 dbSNP
rs1053219026 1486 dbSNP
rs35499134 1486 dbSNP
rs892859815 1486 dbSNP
rs1256708783 1489 dbSNP
rs1344442128 1498 dbSNP
rs10558297 1500 dbSNP
rs140529258 1500 dbSNP
rs563063224 1500 dbSNP
rs577600276 1500 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 55884.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_018639 | 3UTR | CAGAUUAUACAAGGAUGUAUUCUUAAACCGCAUGACUAUUCAGAUGGCUACUGAGUUAUCAGUGGCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUGGUGUAGUCAUGACUUUAGCUGAUACUCUUAUGUACGAGAUCUGUCUCUGCUGUUUAACUUCAUUGGAUUAAUCAGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_018639 | 3UTR | GCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_018639 | 3UTR | GAUUAUACAAGGAUGUAUUCUUAAACCGCAUGACUAUUCAGAUGGCUACUGAGUUAUCAGUGGCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUGGUGUAGUCAUGACUUUAGCUGAUACUCUUAUGUACGAGAUCUGUCUCUGCUGUUUAACUUCAUUGGAUUAAUCAGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_018639 | 3UTR | GUGGCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUGGUGUAGUCAUGACUUUAGCUGAUACUCUUAUGUACGAGAUCUGUCUCUGCUGUUUAACUUCAUUGGAUUAAUCAGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_018639 | 3UTR | GAUUAUACAAGGAUGUAUUCUUAAACCGCAUGACUAUUCAGAUGGCUACUGAGUUAUCAGUGGCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUGGUGUAGUCAUGACUUUAGCUGAUACUCUUAUGUACGAGAUCUGUCUCUGCUGUUUAACUUCAUUGGAUUAAUCAGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_018639 | 3UTR | AGUGGCCAUUUAUUAGCAUCAUAUUUAUUUGUAUUUUCUCAACAGAUGUUAAGGUACAACUGUGUUUUUCUCGAUUAUCUAAAAACCAUAGUACUUAAAUUGAACAGUUGCAAAGAUGUCUUAAUUGUGUAAAGAAUUGGUGUAGUCAUGACUUUAGCUGAUACUCUUAUGUACGAGAUCUGUCUCUGCUGUUUAACUUCAUUGGAUUAAUCAGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000315436.3 | 3UTR | AUUAUCUAAAAACCAUAGUACUUAAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
56 hsa-miR-4760-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT076215 ALKBH5 alkB homolog 5, RNA demethylase 2 2
MIRT087763 H1F0 H1 histone family member 0 2 2
MIRT093991 SLAIN2 SLAIN motif family member 2 2 2
MIRT109199 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT243167 SOX11 SRY-box 11 2 2
MIRT290697 POLI DNA polymerase iota 2 2
MIRT352597 PTMA prothymosin, alpha 2 4
MIRT443107 DENND5B DENN domain containing 5B 2 2
MIRT445651 ATP6V1G1 ATPase H+ transporting V1 subunit G1 2 6
MIRT449111 PHEX phosphate regulating endopeptidase homolog X-linked 2 2
MIRT449798 ZNF74 zinc finger protein 74 2 2
MIRT456143 RWDD2A RWD domain containing 2A 2 18
MIRT463303 ZFP36L1 ZFP36 ring finger protein like 1 2 6
MIRT466904 STK38 serine/threonine kinase 38 2 10
MIRT492452 RBPJ recombination signal binding protein for immunoglobulin kappa J region 2 8
MIRT511574 HIST2H3D histone cluster 2 H3 family member d 2 4
MIRT519374 FKBP14 FK506 binding protein 14 2 2
MIRT520935 SRSF4 serine and arginine rich splicing factor 4 2 4
MIRT524345 CREB1 cAMP responsive element binding protein 1 2 2
MIRT530230 WSB2 WD repeat and SOCS box containing 2 2 2
MIRT531864 POF1B premature ovarian failure, 1B 2 2
MIRT534916 PTPN4 protein tyrosine phosphatase, non-receptor type 4 2 2
MIRT536707 IKZF2 IKAROS family zinc finger 2 2 2
MIRT543555 RPF2 ribosome production factor 2 homolog 2 4
MIRT545247 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545376 PM20D2 peptidase M20 domain containing 2 2 2
MIRT548107 GDAP2 ganglioside induced differentiation associated protein 2 2 2
MIRT548301 EPHA7 EPH receptor A7 2 2
MIRT551453 CARKD NAD(P)HX dehydratase 2 2
MIRT553195 UBE2A ubiquitin conjugating enzyme E2 A 2 2
MIRT559416 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT561360 YOD1 YOD1 deubiquitinase 2 2
MIRT561380 TWF1 twinfilin actin binding protein 1 2 2
MIRT562062 KLHL15 kelch like family member 15 2 2
MIRT563482 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT563510 APOOL apolipoprotein O like 2 2
MIRT571391 MRPL19 mitochondrial ribosomal protein L19 2 2
MIRT573764 PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1 2 2
MIRT576963 Anxa4 annexin A4 2 3
MIRT611048 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT614297 ARL6IP6 ADP ribosylation factor like GTPase 6 interacting protein 6 2 2
MIRT619715 FCF1 FCF1, rRNA-processing protein 2 2
MIRT622278 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT622624 PPM1K protein phosphatase, Mg2+/Mn2+ dependent 1K 2 2
MIRT624730 ANXA4 annexin A4 2 3
MIRT626553 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT649762 USP22 ubiquitin specific peptidase 22 2 2
MIRT652063 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT653045 STON2 stonin 2 2 2
MIRT660573 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT686243 ZFR zinc finger RNA binding protein 2 2
MIRT703405 FZD6 frizzled class receptor 6 2 2
MIRT709480 LOXL2 lysyl oxidase like 2 2 2
MIRT711268 SDR9C7 short chain dehydrogenase/reductase family 9C member 7 2 2
MIRT711426 PROSER2 proline and serine rich 2 2 2
MIRT720030 CDK13 cyclin dependent kinase 13 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-4760 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-miR-4760-5p Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)

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