miRTarBase - #MIRT531521


—
pre-miRNA Information
pre-miRNA hsa-mir-4486   
Genomic Coordinates chr11: 19575310 - 19575372
Description Homo sapiens miR-4486 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4486
Sequence 5| GCUGGGCGAGGCUGGCA |21
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs774299284 8 dbSNP
rs902172817 14 dbSNP
rs1222795726 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol NOM1   
Synonyms C7orf3, PPP1R113, SGD1
Description nucleolar protein with MIF4G domain 1
Transcript NM_138400   
Expression
Putative miRNA Targets on NOM1
3'UTR of NOM1
(miRNA target sites are highlighted)		 
>NOM1|NM_138400|3'UTR
   1 TCAGGGAAGGAAGGAGGGCAGGTGGCCCTTTGACTGTAAAATGTCCTTGGTAAACCCAAAGGCTTATTCTGTTGCCTGCG
  81 TGTGAATGTTTGGTAGAGCTATATCATTGTCTGTTAATGTATTATATTTTGAGATTTTTTTTGATCTAAGGTTTTATTGT
 161 TTGTATTTCAAGCCATTTTCAAATAACTATCTTGGGGGTGAGAGGAGAAGGAGGGAGGGAAAAGGGGTCAGGCACACTGG
 241 ACAGGGTTCTCTAAGCAGTGAGGCTGGTGTGTATGATTGTCTTAAAATTTTTTAATAGATATGGCCGAGCGTGATGGCTC
 321 ACCCCTGTAATCCCAGCACTTTGTGAGGCCAAGGTGGGCGGATCACTTGAGGCCAGGAATTTGAAACCAGCCTGGGCAAA
 401 ACCCTGTCTCTACTAAAAATATAAAAATTAGCCAGGCATGATGGCACATGCTGGTAATAGCAGCTACTGAGGTGGCTGAG
 481 GCACAAGAATTGCTTGGACCCTGGAGGTAGAGGCTGCAGTGAGCCAAGATTGTACCACTGTACTCCAGCCTGGGCTGGAC
 561 AGTGAGACTTTTGACAGTGAGACTGTCAAAAAAAAAAAAAAAATTAATAGATAAAACAGGCCACTAGAGGGTGCAGTTAT
 641 AAAGAAATTGATGAGGTTTTTACCTTTTTAAAATATTGGTTAGAAGTTCAAAAACCATCCCTTAAAGGTGATTGTTTTTT
 721 TGAGACAGAGTCTTGCTCTGTCACCCAGAGTGGAGTGCAGTGTCCTGTAATCTCAGCTCACTGCAACCTCTACCTCCCGG
 801 GTTCAAGCGATTCTCCTGCCTCAGCCTCTTTAGCTGGGACTACAGGCGCACGCCACCACGCCCGGCTAATTTTTGTATTT
 881 TAGTAGAGATGGGTTTCACCATGTTGGCAAGGCTGGTCTTGAACTCCTGACCTCAGGTGATACACCCATCTCGGCCTCCC
 961 AAAGTGCTGGGATTACAGGCTTGAGCCACCACGCCCAGCTTAAATGTGATTCTTGATACTGTTTTAAGTATTTAGGTTGC
1041 AATTAACTTTGGCAAAGTCAGTCGACATAAGCCCTGTGGATATGGCCTTATGTACACTGTAATGCAGACAGGTGCTTTTC
1121 ATCATTCATGTAACATTCTCACACAGTTGAGGATATTCATCTCCTCACCAATTCCAGATTGTAAATGTACCATCTTAAAC
1201 AACTCTGAGGTCACCAAACAGTAGTTATTTGACTGTTAATAGGTGCTACTTGCTTGCAAGGATTTGGAGATGTAAACATG
1281 AAGAAAATATAGTTACTGCCTGCAAAGAATTAACATCCGTCTAGTGGGAGAAACAAACACACCCCACTCACTAAGTATGG
1361 AAAACTGATTCTGGGAGGAAGCAGAAATGTCCCTAGATAACAGCATGTATTGCAGATACCCAAATGTTTATTGTTTTCTC
1441 AGCCCTTCAATTTTGCTTTTCTCTCTCAAATGCTACAGACTCAATTTAAATCTTACCTTTGATTGTTGAAAAAAGTCACT
1521 AAGATGTGAATACAGAATAGACATTGAGAGGTTATATATGTCCAAAACTCATCTGTCCAGCAGTCACCGTCCTCTTCAGA
1601 GTGGTCACGTTGGGCAGATGGGCACAGGTGCTGGTGATGCCTCTCCTGGGCAAAACGCCCCATTTGTGGCACTTTCAGAT
1681 ACTATTTATTTACTTTTTAAGAGAGAGACAGGCTCACTCTGTCACCCAGGCCAGAGTGCAGTGGCACGATCATAGTTACC
1761 GCAGCATCAAATTCCTGGACTGAAGCGGTCCTTTTGCCTCAGCCTCGCGGATAGCTAGGACCACAAGCAGTAGAGACAAG
1841 ATCTCCGTATGTTATACAGGCTGGCCTCAAGTGATCCTCTTACCTTGGCCTCCCAAACACCGGGATTATAGGCGTGAGCC
1921 CCCGTGCCTGGCCTCAAATTTTATTTTAGCTCGACCCTATGGCAGTTTGTGTTTGGAAATCGTGATGTGAAGTCATCAGT
2001 ATCTGTGCATATCCCTAAACTAATGGTTTAAGCTTTGAAGCATGCGCAAGCAACATGAACAACTGAATACAGAAAGTAAC
2081 TGAAAGCAGCACAGAGACTGTGTCGTCCCTACAGACTTCTAACCCTGCATTCAGCAACATCATTCGACCCGAAGCCAGAT
2161 TCAAACCCTATGTCTTCTAGCAGGTTCTGAATTTAGAGGACAAATAAGGTGACAGGTACTAAGAGAAGAGTGAATTAAGT
2241 GAAAATCTTCCCTTTGTTAAGGAGCTTTTTAACAAGAGTGTCTTTGCTGGGTGGTGATTGGGATGTAACAGATCAGTTCT
2321 ACTGGACTTGTAGCTTGATAGTGAAATAAGGAGCTTGGGCTAAGGTATAAATCAACACACTGCTTCCTTCCTCCAGAAGG
2401 TCTTACTGTGAAGGAAAAAATGTCAGTTGAACTAAATTGTGCTTCACGCCTCGGTAGATTTGCATTCTGATGCAAGCCCC
2481 CAACCTCACGGACCAAGAGGATCCCTGGCTGCCTGTGAATGGCCCACATTTGAGTGGTGCTAACTTGATGTGAGTAGGCA
2561 TTAATTATGGGTGCGGCTACTAAGATGGGAAAAACTATCACGACAGTGGCACCACCTGATTTCATGATGTACCATATGCA
2641 GTAACCCATGTTTGAGGTACAGAATTGAAGCTGATTTTTCTGCAAAAGATGAATTTCTATAAACAATCCCATTTTTATAT
2721 TTTATTATTAAAACAAAAATACCTCTCTTTGCTAGAGAGTTATATGTATGACTTAAATTATTAGCTATGGTTTGCATTTA
2801 GTACATGGCAGATTGCCTGTAAGTCTGTTCATTTTAACAACATACAGGGCTGGGCACGGTGGCTCACGCCTGTAATCCCA
2881 GCACTTTGGGAGGTTGCGGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTC
2961 TATGAAAAATATAAAAATTAGCTGGGCATGGTGGCAGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAAT
3041 CGCTTGAACCTGGGAGGCGGATGTTGCAGTGAGCAGAGATCGTGCCATTGCACTCCAGCCTGGGAACAAGAGTGAAACTC
3121 TCAAAAGCAGAAACAAAAACCCAACATATATGGGCTGTTAGATAGTAATTGTAATTTCGTATAAATAGTAAATGAGTACA
3201 TCTTGATTAAAAGCTATGAATTCAGAATTGCTTTTAAATATATAGGGGGTTTTTTGAAATTTATTACAGTGCAATTGAAA
3281 ATACACTTAAAATACTGCAGGATGCTTAGTGCTCAGTGTTATGTATGAACTTGTGGACTTTACAATGCAGGTTGAGAACT
3361 GCTAATGTATAGAATGACTAAACAGCTGTCTTTCAGGGTATCATTTTTAAAGGTATAAGGAACAAACTTTAATGTATTGA
3441 AATGCATAAATAAAATTTATTTTTTATATTTTGTTTAGAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acGGUCGGAGCGGGUCg 5'
            ||| || ||||||| 
Target 5' agCCA-CCACGCCCAGc 3'
 984 - 999 154.00 -25.60
2 
miRNA  3' acGGUCGGAGCGGGUCg 5'
            ||| || |||||:| 
Target 5' cgCCA-CCACGCCCGGc 3'
 851 - 866 138.00 -24.30
3 
miRNA  3' acGGUCGG--AGCGGGUCg 5'
            :|| :|  || ||||| 
Target 5' gcTCACTCTGTCACCCAGg 3'
 1712 - 1730 117.00 -10.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31494605 10 COSMIC
COSN30521602 15 COSMIC
COSN31504645 49 COSMIC
COSN18732209 50 COSMIC
COSN31581436 69 COSMIC
COSN30467774 81 COSMIC
COSN30493867 137 COSMIC
COSN24758653 144 COSMIC
COSN20105022 573 COSMIC
COSN20105027 604 COSMIC
COSN32061221 604 COSMIC
COSN16698670 809 COSMIC
COSN20105029 1172 COSMIC
COSN20091723 1173 COSMIC
COSN20105030 1207 COSMIC
COSN32057802 1451 COSMIC
COSN24791212 1718 COSMIC
COSN20105035 1874 COSMIC
COSN26429896 2171 COSMIC
COSN32205197 2458 COSMIC
COSN20105040 2711 COSMIC
COSN20105041 2762 COSMIC
COSN14975476 3055 COSMIC
COSN20105046 3403 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1182893770 4 dbSNP
rs780062169 5 dbSNP
rs777133802 10 dbSNP
rs980932455 14 dbSNP
rs201754070 15 dbSNP
rs376260339 16 dbSNP
rs778521293 18 dbSNP
rs961423184 19 dbSNP
rs1191762457 24 dbSNP
rs747729833 28 dbSNP
rs1161322490 29 dbSNP
rs1478956874 34 dbSNP
rs973129473 36 dbSNP
rs771553826 40 dbSNP
rs1437171021 42 dbSNP
rs772928233 47 dbSNP
rs746695217 49 dbSNP
rs3087905 50 dbSNP
rs754714057 55 dbSNP
rs1318764326 57 dbSNP
rs958076239 75 dbSNP
rs1364788984 76 dbSNP
rs1191323135 78 dbSNP
rs1442098054 80 dbSNP
rs554422793 81 dbSNP
rs1212712316 87 dbSNP
rs538229150 89 dbSNP
rs1279504665 98 dbSNP
rs556291100 107 dbSNP
rs1249048890 108 dbSNP
rs1285608252 108 dbSNP
rs1316935468 125 dbSNP
rs1355666370 127 dbSNP
rs1051435614 135 dbSNP
rs989229324 136 dbSNP
rs747270668 137 dbSNP
rs914956151 144 dbSNP
rs1039525659 149 dbSNP
rs771117986 152 dbSNP
rs1042418631 158 dbSNP
rs898336289 181 dbSNP
rs537032205 187 dbSNP
rs901445236 190 dbSNP
rs1464206808 196 dbSNP
rs934192887 199 dbSNP
rs1248172184 200 dbSNP
rs1049931284 204 dbSNP
rs889995003 209 dbSNP
rs1046882285 214 dbSNP
rs776632631 218 dbSNP
rs189873921 221 dbSNP
rs897201326 230 dbSNP
rs1194717958 244 dbSNP
rs1335144740 251 dbSNP
rs1274660899 259 dbSNP
rs994196943 264 dbSNP
rs1333165776 272 dbSNP
rs1462107427 279 dbSNP
rs1325774632 287 dbSNP
rs1348454949 293 dbSNP
rs61086249 299 dbSNP
rs1436234688 300 dbSNP
rs1280625735 301 dbSNP
rs1338017736 301 dbSNP
rs1024686166 302 dbSNP
rs12670229 303 dbSNP
rs1229690411 307 dbSNP
rs144397206 308 dbSNP
rs1327871439 311 dbSNP
rs182837764 312 dbSNP
rs1291608360 314 dbSNP
rs542438768 315 dbSNP
rs959223106 323 dbSNP
rs769185185 325 dbSNP
rs770187584 327 dbSNP
rs915010894 331 dbSNP
rs966840495 333 dbSNP
rs1468544106 334 dbSNP
rs1021019613 337 dbSNP
rs1179940125 354 dbSNP
rs1411244812 359 dbSNP
rs1475592708 360 dbSNP
rs977789159 361 dbSNP
rs13244861 366 dbSNP
rs954978576 377 dbSNP
rs56892463 395 dbSNP
rs13230958 398 dbSNP
rs13244873 399 dbSNP
rs1411958289 403 dbSNP
rs922229712 408 dbSNP
rs13230962 411 dbSNP
rs1239969224 422 dbSNP
rs201149415 423 dbSNP
rs55786535 423 dbSNP
rs1439039685 424 dbSNP
rs975369234 428 dbSNP
rs574844634 432 dbSNP
rs1318795237 438 dbSNP
rs58414508 441 dbSNP
rs1372932586 446 dbSNP
rs1408468481 451 dbSNP
rs74480216 467 dbSNP
rs911461159 468 dbSNP
rs1396395467 470 dbSNP
rs1191172099 479 dbSNP
rs745617681 480 dbSNP
rs1477519874 481 dbSNP
rs1349282883 501 dbSNP
rs1242323218 503 dbSNP
rs941521989 505 dbSNP
rs1038919578 507 dbSNP
rs1217035969 509 dbSNP
rs1449099575 511 dbSNP
rs1284247060 512 dbSNP
rs919751620 513 dbSNP
rs1349175454 515 dbSNP
rs897240128 521 dbSNP
rs994624325 526 dbSNP
rs531520094 534 dbSNP
rs1280931685 536 dbSNP
rs1367255725 538 dbSNP
rs1270999106 541 dbSNP
rs1285564020 545 dbSNP
rs1045807522 551 dbSNP
rs113101962 557 dbSNP
rs888947511 558 dbSNP
rs1377172939 565 dbSNP
rs1432085923 569 dbSNP
rs71189969 569 dbSNP
rs367763400 573 dbSNP
rs370503957 574 dbSNP
rs1419520965 576 dbSNP
rs1187914581 580 dbSNP
rs1474192130 586 dbSNP
rs1261515802 587 dbSNP
rs745911051 587 dbSNP
rs1216580895 588 dbSNP
rs1273744846 588 dbSNP
rs34059380 588 dbSNP
rs75300331 588 dbSNP
rs949164137 593 dbSNP
rs1202884544 601 dbSNP
rs1415155805 603 dbSNP
rs1251009964 604 dbSNP
rs1486027406 605 dbSNP
rs1046025866 606 dbSNP
rs904896100 610 dbSNP
rs1354633465 612 dbSNP
rs1189754271 621 dbSNP
rs1171849756 628 dbSNP
rs1001472555 632 dbSNP
rs1235940621 634 dbSNP
rs35240211 634 dbSNP
rs1407894992 637 dbSNP
rs1422457880 640 dbSNP
rs1472624209 642 dbSNP
rs1168720389 662 dbSNP
rs1259981635 663 dbSNP
rs1180649710 665 dbSNP
rs1002401852 670 dbSNP
rs1206690192 671 dbSNP
rs761618057 680 dbSNP
rs569827000 686 dbSNP
rs187314588 692 dbSNP
rs60522833 700 dbSNP
rs1021554673 715 dbSNP
rs1310249333 717 dbSNP
rs112174292 738 dbSNP
rs1373922516 739 dbSNP
rs1299445705 740 dbSNP
rs563742054 748 dbSNP
rs1017604261 752 dbSNP
rs770156685 757 dbSNP
rs1165216142 767 dbSNP
rs1010713552 771 dbSNP
rs964742422 787 dbSNP
rs559519902 790 dbSNP
rs12698009 792 dbSNP
rs919816823 795 dbSNP
rs1338209404 797 dbSNP
rs1409335928 799 dbSNP
rs966495952 800 dbSNP
rs1456503215 804 dbSNP
rs978281815 809 dbSNP
rs922375800 810 dbSNP
rs1263493709 814 dbSNP
rs1243763649 821 dbSNP
rs982576712 829 dbSNP
rs199768636 836 dbSNP
rs908372274 848 dbSNP
rs955051715 849 dbSNP
rs12698010 852 dbSNP
rs567916839 853 dbSNP
rs541086804 860 dbSNP
rs941553020 861 dbSNP
rs1038542636 864 dbSNP
rs1250187440 865 dbSNP
rs1455781966 885 dbSNP
rs1265534932 890 dbSNP
rs868090677 891 dbSNP
rs372503362 893 dbSNP
rs1053405208 894 dbSNP
rs894033904 901 dbSNP
rs550119543 902 dbSNP
rs571567084 905 dbSNP
rs1214402326 907 dbSNP
rs1427378014 917 dbSNP
rs1352859292 922 dbSNP
rs192211075 926 dbSNP
rs1235835518 933 dbSNP
rs1329061335 937 dbSNP
rs1009782692 941 dbSNP
rs11767045 943 dbSNP
rs890660873 945 dbSNP
rs1300391183 946 dbSNP
rs572249470 948 dbSNP
rs35773952 950 dbSNP
rs1174399914 952 dbSNP
rs1399380244 953 dbSNP
rs964690758 954 dbSNP
rs994808715 960 dbSNP
rs1413428811 961 dbSNP
rs554349413 969 dbSNP
rs764336898 973 dbSNP
rs1191208446 979 dbSNP
rs560807592 980 dbSNP
rs1280950695 981 dbSNP
rs1055699460 982 dbSNP
rs1212850175 983 dbSNP
rs1342275636 987 dbSNP
rs576261274 993 dbSNP
rs543370094 994 dbSNP
rs1327795307 996 dbSNP
rs1280539383 997 dbSNP
rs1398526334 1006 dbSNP
rs983143775 1010 dbSNP
rs1011206906 1020 dbSNP
rs1022206873 1026 dbSNP
rs902386170 1034 dbSNP
rs1314038408 1041 dbSNP
rs1398259433 1048 dbSNP
rs908364310 1053 dbSNP
rs1432628917 1061 dbSNP
rs1172040095 1065 dbSNP
rs1296672217 1073 dbSNP
rs970995812 1080 dbSNP
rs1331484292 1093 dbSNP
rs1168357123 1097 dbSNP
rs565220686 1109 dbSNP
rs1257891838 1110 dbSNP
rs369905665 1110 dbSNP
rs1440587164 1112 dbSNP
rs1344373344 1113 dbSNP
rs576743057 1113 dbSNP
rs1341106322 1115 dbSNP
rs1209485364 1124 dbSNP
rs1270250856 1128 dbSNP
rs1317716036 1133 dbSNP
rs1463762235 1134 dbSNP
rs1029428909 1145 dbSNP
rs183491447 1147 dbSNP
rs926342653 1148 dbSNP
rs1339205739 1149 dbSNP
rs4434512 1154 dbSNP
rs1268414958 1159 dbSNP
rs1435306608 1161 dbSNP
rs1329576558 1162 dbSNP
rs1197309755 1169 dbSNP
rs553367102 1170 dbSNP
rs529823835 1173 dbSNP
rs1159343441 1175 dbSNP
rs71516461 1191 dbSNP
rs4326276 1192 dbSNP
rs4434513 1193 dbSNP
rs531997273 1194 dbSNP
rs1043068991 1200 dbSNP
rs1458714975 1202 dbSNP
rs1235777091 1203 dbSNP
rs397728793 1206 dbSNP
rs5888698 1206 dbSNP
rs539496381 1217 dbSNP
rs1274252845 1224 dbSNP
rs750084279 1225 dbSNP
rs1388351583 1228 dbSNP
rs1284132032 1233 dbSNP
rs1240315339 1237 dbSNP
rs1017919249 1242 dbSNP
rs1039214561 1247 dbSNP
rs11763661 1250 dbSNP
rs974770000 1256 dbSNP
rs918827760 1258 dbSNP
rs930165787 1261 dbSNP
rs1325342005 1269 dbSNP
rs377551047 1279 dbSNP
rs1389659177 1293 dbSNP
rs1159100573 1295 dbSNP
rs781407931 1298 dbSNP
rs928743168 1301 dbSNP
rs937387727 1302 dbSNP
rs571935461 1306 dbSNP
rs1055732498 1319 dbSNP
rs1004120029 1320 dbSNP
rs7777379 1324 dbSNP
rs142541442 1330 dbSNP
rs1289551029 1337 dbSNP
rs1206272151 1343 dbSNP
rs1208468211 1346 dbSNP
rs1307236340 1347 dbSNP
rs1228621601 1351 dbSNP
rs1267267595 1354 dbSNP
rs1372082092 1361 dbSNP
rs1044060205 1366 dbSNP
rs1184986551 1371 dbSNP
rs1413441340 1374 dbSNP
rs926467246 1375 dbSNP
rs1471337831 1384 dbSNP
rs902397291 1388 dbSNP
rs1421495495 1391 dbSNP
rs7794906 1394 dbSNP
rs1029461463 1397 dbSNP
rs1434805536 1408 dbSNP
rs1426591000 1415 dbSNP
rs1189118656 1420 dbSNP
rs1477467475 1424 dbSNP
rs1246531338 1428 dbSNP
rs890885174 1431 dbSNP
rs1368726018 1433 dbSNP
rs7777527 1451 dbSNP
rs1216437067 1452 dbSNP
rs554310757 1469 dbSNP
rs1347897291 1475 dbSNP
rs779968803 1476 dbSNP
rs1042628180 1477 dbSNP
rs973751022 1480 dbSNP
rs575231572 1485 dbSNP
rs1338066947 1511 dbSNP
rs1297522373 1515 dbSNP
rs1415273066 1519 dbSNP
rs1360418891 1525 dbSNP
rs150958008 1528 dbSNP
rs142112575 1535 dbSNP
rs912108545 1537 dbSNP
rs1171908138 1538 dbSNP
rs1309813818 1539 dbSNP
rs982021577 1543 dbSNP
rs928774313 1545 dbSNP
rs1348655142 1546 dbSNP
rs1193598259 1547 dbSNP
rs1483848641 1557 dbSNP
rs937503856 1559 dbSNP
rs1239339322 1562 dbSNP
rs991575862 1564 dbSNP
rs749862100 1583 dbSNP
rs947386597 1584 dbSNP
rs79278154 1588 dbSNP
rs900708798 1589 dbSNP
rs577108891 1590 dbSNP
rs540987822 1593 dbSNP
rs935227465 1595 dbSNP
rs559393200 1609 dbSNP
rs1265168736 1610 dbSNP
rs891002772 1612 dbSNP
rs1446641566 1614 dbSNP
rs1354545492 1632 dbSNP
rs1006710402 1637 dbSNP
rs1343321728 1642 dbSNP
rs10260387 1643 dbSNP
rs886420158 1657 dbSNP
rs1005268115 1658 dbSNP
rs1250312529 1658 dbSNP
rs541960459 1659 dbSNP
rs1424962338 1670 dbSNP
rs10260499 1676 dbSNP
rs1180553534 1680 dbSNP
rs1482975420 1683 dbSNP
rs1256409625 1685 dbSNP
rs906409823 1687 dbSNP
rs995599328 1694 dbSNP
rs771633458 1696 dbSNP
rs772868112 1704 dbSNP
rs1222012774 1712 dbSNP
rs1323499492 1715 dbSNP
rs1430187859 1716 dbSNP
rs372762137 1720 dbSNP
rs1170387256 1737 dbSNP
rs1368669429 1739 dbSNP
rs1310485496 1740 dbSNP
rs1441554833 1742 dbSNP
rs1303556108 1745 dbSNP
rs1377019428 1748 dbSNP
rs1310757114 1749 dbSNP
rs531787603 1749 dbSNP
rs959234691 1750 dbSNP
rs1399083623 1751 dbSNP
rs1394441610 1756 dbSNP
rs201969880 1758 dbSNP
rs200027358 1761 dbSNP
rs1366352476 1767 dbSNP
rs951727082 1771 dbSNP
rs1423704014 1775 dbSNP
rs966506029 1776 dbSNP
rs1438128164 1779 dbSNP
rs1273102433 1783 dbSNP
rs1003115046 1787 dbSNP
rs1035903250 1788 dbSNP
rs1263402110 1798 dbSNP
rs1220779793 1806 dbSNP
rs191799507 1807 dbSNP
rs760132033 1808 dbSNP
rs991607044 1809 dbSNP
rs914657125 1810 dbSNP
rs1237323875 1820 dbSNP
rs1183136503 1832 dbSNP
rs565426690 1837 dbSNP
rs1301559427 1845 dbSNP
rs182538593 1847 dbSNP
rs547360834 1848 dbSNP
rs75027313 1849 dbSNP
rs1388230455 1850 dbSNP
rs1409242347 1852 dbSNP
rs933313534 1856 dbSNP
rs1417943278 1858 dbSNP
rs1379704786 1861 dbSNP
rs199571040 1872 dbSNP
rs35889324 1873 dbSNP
rs397977765 1873 dbSNP
rs373350325 1875 dbSNP
rs375278584 1876 dbSNP
rs369640012 1877 dbSNP
rs930822606 1878 dbSNP
rs34351910 1883 dbSNP
rs1336288345 1885 dbSNP
rs886493977 1889 dbSNP
rs1488616643 1902 dbSNP
rs1437708947 1903 dbSNP
rs940794949 1905 dbSNP
rs187131703 1906 dbSNP
rs1256032929 1914 dbSNP
rs570180738 1915 dbSNP
rs868417515 1921 dbSNP
rs376134803 1924 dbSNP
rs1220279279 1925 dbSNP
rs1039534171 1932 dbSNP
rs779786366 1936 dbSNP
rs768430841 1938 dbSNP
rs1304083645 1950 dbSNP
rs1384383776 1953 dbSNP
rs112447111 1954 dbSNP
rs995233692 1955 dbSNP
rs781300829 1957 dbSNP
rs1047245650 1960 dbSNP
rs894966506 1966 dbSNP
rs1465111884 1967 dbSNP
rs192513123 1970 dbSNP
rs1245894917 1980 dbSNP
rs184376379 1982 dbSNP
rs780342407 1983 dbSNP
rs1256309381 1986 dbSNP
rs1201658724 1988 dbSNP
rs1482108116 1989 dbSNP
rs1255051265 1993 dbSNP
rs1035934541 1996 dbSNP
rs1218794583 1999 dbSNP
rs1319063131 2004 dbSNP
rs1280444829 2024 dbSNP
rs1217377498 2025 dbSNP
rs966820975 2031 dbSNP
rs958921162 2034 dbSNP
rs6952436 2035 dbSNP
rs574468624 2040 dbSNP
rs769295535 2042 dbSNP
rs115710772 2043 dbSNP
rs1466306036 2044 dbSNP
rs969282583 2046 dbSNP
rs977571436 2047 dbSNP
rs1189447083 2050 dbSNP
rs1421552778 2055 dbSNP
rs1254806253 2074 dbSNP
rs1318824127 2077 dbSNP
rs190528985 2080 dbSNP
rs1437695596 2084 dbSNP
rs1260446672 2088 dbSNP
rs984923352 2092 dbSNP
rs908038673 2099 dbSNP
rs924670965 2101 dbSNP
rs779507716 2106 dbSNP
rs77148861 2108 dbSNP
rs1447861678 2109 dbSNP
rs912502594 2112 dbSNP
rs1409157094 2116 dbSNP
rs1391105330 2117 dbSNP
rs1164949943 2124 dbSNP
rs942555924 2131 dbSNP
rs1384112300 2134 dbSNP
rs1178689946 2140 dbSNP
rs1045848769 2142 dbSNP
rs543608991 2146 dbSNP
rs772437459 2147 dbSNP
rs773415060 2150 dbSNP
rs565498768 2151 dbSNP
rs1229804908 2152 dbSNP
rs1290988213 2161 dbSNP
rs746720886 2169 dbSNP
rs1055742406 2170 dbSNP
rs1354838274 2178 dbSNP
rs770474819 2190 dbSNP
rs1046835744 2204 dbSNP
rs74565995 2218 dbSNP
rs1379119621 2219 dbSNP
rs1307360373 2221 dbSNP
rs938366148 2224 dbSNP
rs1331502900 2235 dbSNP
rs1056684195 2243 dbSNP
rs1403580496 2248 dbSNP
rs902376043 2249 dbSNP
rs1159110390 2250 dbSNP
rs1421003195 2251 dbSNP
rs1377896140 2254 dbSNP
rs1248372012 2258 dbSNP
rs1478136549 2265 dbSNP
rs1247709570 2274 dbSNP
rs1201448196 2276 dbSNP
rs1490022742 2283 dbSNP
rs1268801266 2286 dbSNP
rs541311194 2288 dbSNP
rs966205375 2292 dbSNP
rs995813420 2294 dbSNP
rs1013153281 2295 dbSNP
rs774625927 2297 dbSNP
rs1022290577 2303 dbSNP
rs1028670010 2310 dbSNP
rs1412750611 2314 dbSNP
rs758979672 2315 dbSNP
rs952236513 2317 dbSNP
rs1157194308 2323 dbSNP
rs999415531 2324 dbSNP
rs1407577081 2329 dbSNP
rs145928467 2331 dbSNP
rs1358120506 2333 dbSNP
rs908027552 2334 dbSNP
rs138859538 2340 dbSNP
rs1426828275 2342 dbSNP
rs1170373339 2348 dbSNP
rs987471822 2349 dbSNP
rs1348511743 2355 dbSNP
rs1428965205 2359 dbSNP
rs1404803821 2367 dbSNP
rs759965586 2368 dbSNP
rs3800868 2370 dbSNP
rs937441670 2376 dbSNP
rs1055690112 2379 dbSNP
rs914611979 2380 dbSNP
rs1411177625 2381 dbSNP
rs1277406312 2387 dbSNP
rs1220452849 2395 dbSNP
rs964700190 2395 dbSNP
rs1338324079 2401 dbSNP
rs1269150120 2413 dbSNP
rs1349580325 2414 dbSNP
rs1228549897 2415 dbSNP
rs975396610 2415 dbSNP
rs1331814620 2427 dbSNP
rs946625604 2433 dbSNP
rs919820769 2442 dbSNP
rs1342547276 2448 dbSNP
rs570013559 2449 dbSNP
rs567088503 2453 dbSNP
rs73506062 2454 dbSNP
rs1186375972 2458 dbSNP
rs999342389 2464 dbSNP
rs1239245475 2466 dbSNP
rs1202054490 2471 dbSNP
rs1484061286 2472 dbSNP
rs1040622482 2473 dbSNP
rs570675866 2474 dbSNP
rs868273504 2478 dbSNP
rs3800867 2491 dbSNP
rs1028661527 2496 dbSNP
rs951726827 2497 dbSNP
rs1228764199 2520 dbSNP
rs1056799113 2529 dbSNP
rs1006466805 2533 dbSNP
rs1380744337 2537 dbSNP
rs894182920 2539 dbSNP
rs1015202500 2543 dbSNP
rs1232501648 2547 dbSNP
rs1473213937 2560 dbSNP
rs1165223001 2561 dbSNP
rs193220591 2569 dbSNP
rs1467514172 2571 dbSNP
rs1353072537 2572 dbSNP
rs1043343306 2573 dbSNP
rs1406430234 2574 dbSNP
rs11765440 2575 dbSNP
rs3823623 2576 dbSNP
rs1180686679 2577 dbSNP
rs1479547429 2582 dbSNP
rs1250509146 2598 dbSNP
rs756428570 2599 dbSNP
rs115300146 2600 dbSNP
rs1323404604 2600 dbSNP
rs184341099 2602 dbSNP
rs1334668542 2603 dbSNP
rs1448251884 2617 dbSNP
rs1244597271 2624 dbSNP
rs1285620533 2625 dbSNP
rs1380280535 2628 dbSNP
rs1389283648 2631 dbSNP
rs914559714 2635 dbSNP
rs947413237 2636 dbSNP
rs545900488 2638 dbSNP
rs1352123079 2640 dbSNP
rs1017701044 2641 dbSNP
rs1238118009 2645 dbSNP
rs7803794 2647 dbSNP
rs779220848 2650 dbSNP
rs973800704 2656 dbSNP
rs1417518381 2658 dbSNP
rs1026918608 2659 dbSNP
rs1272293240 2660 dbSNP
rs755056982 2667 dbSNP
rs150381176 2671 dbSNP
rs1266686420 2672 dbSNP
rs1221575799 2683 dbSNP
rs541277479 2701 dbSNP
rs1189818715 2704 dbSNP
rs982641137 2707 dbSNP
rs35711429 2708 dbSNP
rs796880341 2708 dbSNP
rs1189679279 2709 dbSNP
rs200434237 2709 dbSNP
rs386720105 2709 dbSNP
rs78759877 2710 dbSNP
rs34221441 2711 dbSNP
rs1220185780 2712 dbSNP
rs1428310989 2712 dbSNP
rs138683704 2717 dbSNP
rs1395085942 2718 dbSNP
rs1361291097 2722 dbSNP
rs1404834264 2722 dbSNP
rs1290682073 2728 dbSNP
rs1414594765 2730 dbSNP
rs1363432983 2740 dbSNP
rs992558893 2746 dbSNP
rs748727755 2750 dbSNP
rs1176975905 2755 dbSNP
rs1434698893 2756 dbSNP
rs11321727 2760 dbSNP
rs1198656476 2762 dbSNP
rs1403538464 2767 dbSNP
rs915647477 2769 dbSNP
rs1488564923 2772 dbSNP
rs1451624056 2773 dbSNP
rs558206631 2782 dbSNP
rs1043091102 2783 dbSNP
rs1485223589 2785 dbSNP
rs1256245000 2787 dbSNP
rs113638791 2795 dbSNP
rs1326143930 2805 dbSNP
rs747328750 2806 dbSNP
rs1053358116 2818 dbSNP
rs1223491465 2844 dbSNP
rs113449808 2846 dbSNP
rs1341662721 2846 dbSNP
rs7786691 2847 dbSNP
rs958890704 2858 dbSNP
rs1384272711 2859 dbSNP
rs1009052777 2860 dbSNP
rs1303666913 2868 dbSNP
rs181513455 2869 dbSNP
rs866267874 2880 dbSNP
rs1039166974 2887 dbSNP
rs968786467 2893 dbSNP
rs1261491442 2894 dbSNP
rs900561472 2898 dbSNP
rs994868154 2899 dbSNP
rs1028032827 2900 dbSNP
rs530874171 2904 dbSNP
rs1256197765 2910 dbSNP
rs1201860289 2911 dbSNP
rs1459679010 2917 dbSNP
rs1427132948 2919 dbSNP
rs776206747 2925 dbSNP
rs1378762272 2926 dbSNP
rs1318956643 2930 dbSNP
rs1478069683 2933 dbSNP
rs1225812616 2945 dbSNP
rs950736611 2951 dbSNP
rs552623847 2954 dbSNP
rs745414243 2956 dbSNP
rs1380852254 2957 dbSNP
rs924608843 2959 dbSNP
rs1426602770 2961 dbSNP
rs1015445914 2970 dbSNP
rs184149792 2972 dbSNP
rs1166123621 2973 dbSNP
rs1390499458 2980 dbSNP
rs1380360555 2982 dbSNP
rs923088402 2983 dbSNP
rs528290874 2984 dbSNP
rs992591365 2986 dbSNP
rs546854373 2989 dbSNP
rs1317514879 2992 dbSNP
rs1442464495 3000 dbSNP
rs1334318300 3001 dbSNP
rs568318635 3002 dbSNP
rs535741526 3003 dbSNP
rs1050271095 3005 dbSNP
rs189748706 3009 dbSNP
rs970188531 3018 dbSNP
rs1253051355 3019 dbSNP
rs546040989 3020 dbSNP
rs1235344946 3021 dbSNP
rs1357304030 3026 dbSNP
rs568822008 3041 dbSNP
rs925638861 3042 dbSNP
rs1281384314 3043 dbSNP
rs540364006 3046 dbSNP
rs539093982 3047 dbSNP
rs1053404337 3050 dbSNP
rs769334843 3055 dbSNP
rs13242102 3059 dbSNP
rs1422228109 3061 dbSNP
rs763006878 3067 dbSNP
rs1384024402 3071 dbSNP
rs1158905410 3074 dbSNP
rs1166798404 3079 dbSNP
rs572642592 3082 dbSNP
rs534848516 3083 dbSNP
rs1437544057 3090 dbSNP
rs1270254451 3093 dbSNP
rs1225311446 3097 dbSNP
rs1268656991 3107 dbSNP
rs1039179735 3108 dbSNP
rs1291098026 3108 dbSNP
rs1370421449 3110 dbSNP
rs1353093364 3111 dbSNP
rs897516455 3128 dbSNP
rs900599841 3135 dbSNP
rs995362145 3139 dbSNP
rs1049128588 3140 dbSNP
rs886480790 3143 dbSNP
rs1004879104 3144 dbSNP
rs1365223541 3150 dbSNP
rs1298261826 3151 dbSNP
rs1402153457 3151 dbSNP
rs1405352546 3155 dbSNP
rs1451353582 3159 dbSNP
rs1157840419 3162 dbSNP
rs1469969584 3163 dbSNP
rs1013008467 3172 dbSNP
rs1015474001 3179 dbSNP
rs959909944 3180 dbSNP
rs1268338488 3182 dbSNP
rs1014061505 3193 dbSNP
rs1448740149 3195 dbSNP
rs1301241231 3201 dbSNP
rs1365664445 3208 dbSNP
rs763937725 3209 dbSNP
rs969903541 3215 dbSNP
rs978942201 3217 dbSNP
rs1284926297 3221 dbSNP
rs1221662469 3245 dbSNP
rs143682725 3250 dbSNP
rs576443912 3250 dbSNP
rs1410561502 3253 dbSNP
rs1342880235 3261 dbSNP
rs1317243970 3262 dbSNP
rs1031664903 3263 dbSNP
rs965788297 3266 dbSNP
rs976007945 3268 dbSNP
rs923160607 3269 dbSNP
rs761462007 3274 dbSNP
rs180994157 3283 dbSNP
rs988439821 3291 dbSNP
rs909051259 3293 dbSNP
rs1238625786 3296 dbSNP
rs185940123 3301 dbSNP
rs542525026 3302 dbSNP
rs1358941822 3316 dbSNP
rs748950622 3317 dbSNP
rs1268858943 3322 dbSNP
rs1036548309 3324 dbSNP
rs1201542534 3326 dbSNP
rs918908320 3328 dbSNP
rs1490034371 3339 dbSNP
rs138309824 3342 dbSNP
rs575572961 3346 dbSNP
rs922119993 3347 dbSNP
rs1269059810 3352 dbSNP
rs1448381829 3355 dbSNP
rs1013123979 3358 dbSNP
rs1334205283 3362 dbSNP
rs1468577538 3365 dbSNP
rs1416870105 3367 dbSNP
rs1043203642 3373 dbSNP
rs1368781685 3375 dbSNP
rs1426371786 3377 dbSNP
rs1167393613 3398 dbSNP
rs200944456 3399 dbSNP
rs10672171 3401 dbSNP
rs368646416 3401 dbSNP
rs373292300 3402 dbSNP
rs397723184 3403 dbSNP
rs1460731172 3404 dbSNP
rs545923370 3410 dbSNP
rs1430477500 3414 dbSNP
rs564559998 3419 dbSNP
rs1371278272 3421 dbSNP
rs1049647436 3426 dbSNP
rs1246074979 3428 dbSNP
rs1360898988 3430 dbSNP
rs1312488295 3438 dbSNP
rs886493173 3444 dbSNP
rs998160251 3445 dbSNP
rs1299079020 3451 dbSNP
rs1445063235 3458 dbSNP
rs1313727004 3463 dbSNP
rs940699185 3469 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 64434.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acggucggagCGGGUCg 5'
                    |||||| 
Target 5' ----------GCCCAGg 3'
 		1 - 7
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000275820.3 | 3UTR | GCCCAGGAGGUGGAAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
108 hsa-miR-4486 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT254654 NF2 neurofibromin 2 2 2
MIRT458684 MRI1 methylthioribose-1-phosphate isomerase 1 2 2
MIRT470845 PLXND1 plexin D1 2 2
MIRT493011 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT497264 GRK6 G protein-coupled receptor kinase 6 2 2
MIRT497675 SYNGR1 synaptogyrin 1 2 2
MIRT498219 TLN2 talin 2 2 2
MIRT498310 BCL11B B-cell CLL/lymphoma 11B 2 2
MIRT504048 TOMM5 translocase of outer mitochondrial membrane 5 2 2
MIRT519959 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT531521 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT533144 WNT10A Wnt family member 10A 2 2
MIRT533541 TPR translocated promoter region, nuclear basket protein 2 2
MIRT533681 TMEM86A transmembrane protein 86A 2 2
MIRT540321 PIGR polymeric immunoglobulin receptor 2 2
MIRT540719 GUF1 GUF1 homolog, GTPase 2 2
MIRT541566 ZNF43 zinc finger protein 43 2 4
MIRT541787 TBCCD1 TBCC domain containing 1 2 2
MIRT541925 ORC1 origin recognition complex subunit 1 2 4
MIRT542232 FUT9 fucosyltransferase 9 2 2
MIRT542285 POLR3K RNA polymerase III subunit K 2 2
MIRT542299 QTRTD1 queuine tRNA-ribosyltransferase accessory subunit 2 2 4
MIRT542368 PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 2
MIRT542441 C3 complement C3 2 4
MIRT542475 APOC3 apolipoprotein C3 2 2
MIRT542535 MRPS10 mitochondrial ribosomal protein S10 2 2
MIRT542640 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT542788 PLEKHA3 pleckstrin homology domain containing A3 2 2
MIRT552104 PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A 2 2
MIRT564913 YTHDF1 YTH N6-methyladenosine RNA binding protein 1 2 2
MIRT568606 ACVR2A activin A receptor type 2A 2 2
MIRT607389 LANCL3 LanC like 3 2 2
MIRT607451 ZNF543 zinc finger protein 543 2 2
MIRT610058 MYBPC1 myosin binding protein C, slow type 2 2
MIRT610793 KLK2 kallikrein related peptidase 2 2 2
MIRT617176 GOSR2 golgi SNAP receptor complex member 2 2 2
MIRT620579 WBSCR27 methyltransferase like 27 2 4
MIRT622085 SRPX2 sushi repeat containing protein, X-linked 2 2 2
MIRT622542 PXMP4 peroxisomal membrane protein 4 2 2
MIRT630009 PDE6B phosphodiesterase 6B 2 2
MIRT631813 PTDSS2 phosphatidylserine synthase 2 2 2
MIRT632721 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT632757 MED28 mediator complex subunit 28 2 2
MIRT634821 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT635255 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT637082 SELPLG selectin P ligand 2 2
MIRT637357 ZNF460 zinc finger protein 460 2 2
MIRT637472 DEFB105B defensin beta 105B 2 4
MIRT637504 DEFB105A defensin beta 105A 2 4
MIRT639022 AAK1 AP2 associated kinase 1 2 2
MIRT641012 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT642170 HEBP2 heme binding protein 2 2 2
MIRT648977 ACAD8 acyl-CoA dehydrogenase family member 8 2 2
MIRT650515 UFM1 ubiquitin fold modifier 1 2 2
MIRT650949 INMT indolethylamine N-methyltransferase 2 2
MIRT658354 FAM65B RHO family interacting cell polarization regulator 2 2 2
MIRT660736 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT662191 MEI1 meiotic double-stranded break formation protein 1 2 2
MIRT663045 SLC16A4 solute carrier family 16 member 4 2 2
MIRT664811 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT665161 SF3A1 splicing factor 3a subunit 1 2 4
MIRT665346 YES1 YES proto-oncogene 1, Src family tyrosine kinase 2 2
MIRT666493 SBNO1 strawberry notch homolog 1 2 2
MIRT666545 RNF115 ring finger protein 115 2 2
MIRT669351 BMP3 bone morphogenetic protein 3 2 2
MIRT669904 KIAA0754 KIAA0754 2 4
MIRT670323 CEP57L1 centrosomal protein 57 like 1 2 2
MIRT670430 ELP2 elongator acetyltransferase complex subunit 2 2 2
MIRT670672 KIAA1551 KIAA1551 2 2
MIRT670746 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670998 PTGIS prostaglandin I2 synthase 2 2
MIRT671290 RPL37A ribosomal protein L37a 2 2
MIRT671469 AGPAT6 glycerol-3-phosphate acyltransferase 4 2 2
MIRT671833 STIL STIL, centriolar assembly protein 2 2
MIRT673006 TAF1 TATA-box binding protein associated factor 1 2 2
MIRT675881 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT678625 OLFML2A olfactomedin like 2A 2 2
MIRT678790 NUPL2 nucleoporin like 2 2 2
MIRT679560 LIN9 lin-9 DREAM MuvB core complex component 2 2
MIRT681032 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682480 LIX1L limb and CNS expressed 1 like 2 2
MIRT682758 MDM2 MDM2 proto-oncogene 2 2
MIRT682810 TMCO1 transmembrane and coiled-coil domains 1 2 2
MIRT682867 C9orf156 tRNA methyltransferase O 2 2
MIRT689233 RPS19 ribosomal protein S19 2 2
MIRT689305 C5AR2 complement component 5a receptor 2 2 2
MIRT689363 ZNF101 zinc finger protein 101 2 2
MIRT689629 NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit 2 2
MIRT689654 RBM23 RNA binding motif protein 23 2 2
MIRT690148 PPIL6 peptidylprolyl isomerase like 6 2 2
MIRT691407 DNA2 DNA replication helicase/nuclease 2 2 2
MIRT691847 OSCAR osteoclast associated, immunoglobulin-like receptor 2 2
MIRT692234 ALDH1B1 aldehyde dehydrogenase 1 family member B1 2 2
MIRT694320 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT694365 CHST6 carbohydrate sulfotransferase 6 2 2
MIRT696215 LYZ lysozyme 2 2
MIRT697230 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT700487 PTPRF protein tyrosine phosphatase, receptor type F 2 2
MIRT700612 PRKCA protein kinase C alpha 2 2
MIRT702456 KIAA1467 family with sequence similarity 234 member B 2 2
MIRT702990 HERPUD2 HERPUD family member 2 2 2
MIRT703998 EIF5A2 eukaryotic translation initiation factor 5A2 2 2
MIRT704701 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT712481 FSTL3 follistatin like 3 2 2
MIRT712781 ZNF154 zinc finger protein 154 2 2
MIRT714369 HP1BP3 heterochromatin protein 1 binding protein 3 2 2
MIRT722570 C1orf95 stum, mechanosensory transduction mediator homolog 2 2
MIRT722839 C17orf102 chromosome 17 open reading frame 102 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4486 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4486 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Curcumin 969516 NSC32982 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4486 Fulvestrant 17756771 NSC719276 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved sensitive High Gastric Cancer cell line (SGC7901)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved sensitive Low Gastric Cancer cell line (SGC-7901)
hsa-mir-4486 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4486 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4486 Temozolomide 5394 NSC362856 approved resistant cell line (U251)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4486 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4486 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4486 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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