pre-miRNA Information | |
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pre-miRNA | hsa-mir-4433a |
Genomic Coordinates | chr2: 64340759 - 64340839 |
Description | Homo sapiens miR-4433a stem-loop |
Comment | None |
RNA Secondary Structure | ![]() |
Mature miRNA Information | |||||||||||||
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Mature miRNA | hsa-miR-4433a-3p | ||||||||||||
Sequence | 51| ACAGGAGUGGGGGUGGGACAU |71 | ||||||||||||
Evidence | Experimental | ||||||||||||
Experiments | Illumina | ||||||||||||
SNPs in miRNA |
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Putative Targets |
miRNA Expression profile | |
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Human miRNA Tissue Atlas | |
Circulating MicroRNA Expression Profiling |
Gene Information | |||||||||||||||||||||
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Gene Symbol | PLEKHA6 | ||||||||||||||||||||
Synonyms | PEPP-3, PEPP3 | ||||||||||||||||||||
Description | pleckstrin homology domain containing A6 | ||||||||||||||||||||
Transcript | NM_014935 | ||||||||||||||||||||
Expression | |||||||||||||||||||||
Putative miRNA Targets on PLEKHA6 | |||||||||||||||||||||
3'UTR of PLEKHA6 (miRNA target sites are highlighted) |
>PLEKHA6|NM_014935|3'UTR 1 GCTCTGACTGCAAGCCCTGGCTGAGGCCAATGCTGTGAAGCTCCACAGAGCCACATTCTGAAGCCGTCCTCTGCCCACCT 81 GAGGTCCTGGCTCCCCACCCTGGCCCCCTGCCCCTGCACTCCCATGGGAATGCCGCAGGGAGCCAGGCTGGGGCCATGGG 161 CTGCTGCCAGAGGACCGTGGATACCTCAGTGTCCACACACCCACCATGCCCAGCCCTGGAGCCATCACTACTCACACCGT 241 GGTCCTGGGCCAGGGCCTGAGATGACAGTGGGGAGCACCATCCTCATTAATGTCCAAGTCACAGGGAGCCTCAGCCTTGC 321 CCTGGCTGGGGTTGTGGTGACTCCAGTGGAACATTCCCTGATGGGGGACATGCCGTGGTGGAGAACACACCTGTGGCTAT 401 CTTATGTGAGGACTAGAGGTGAAGAGGAGATGGACACTGCCTCTGGAGCCAGCCTGACACCAAGGACAGCACTTGTCATC 481 ATCCCTATCCTCGTCAGCCCCACCCTACTGCCTCAGCTGGACCCAGGGCTTTGACACAAACCCAGTGCTTTGCTTATGGG 561 TGCTCGCTGGGGTCCGGTGGAGACTGACCACCCTGCTTGAGCCAAAGACAAGGTGATGAGAGATGGGGAGAGGCCATTGG 641 CTCCCAGAGGGAACAGTGCTGGCTGTGGCTAGAGAACAGCAGGTCTGTGCAGTGTCTGAGGGCAGGTTGGGAAGGGTAGC 721 AGAGAGAGAGAGACAGAAAGAGAGAGAGAGAGAGAGAGAGAGAGAGATCCTCAGAGTGGAAGGAGGGGGAAGCAGCAGGA 801 CACATTGGCAAGTCAAGCAGGAAGGAGGGAGATGGAAAGGGGATATCAGATTGGTTTCCCCCGGTGGAGCCTTAGGTTAG 881 TGCCCAGTGCAGTGCCAGACTGTCTCCTCTGCTCCTCCCACCTCATCCCTAGGAGGACCCACCAGTGGAGCACATGCAGC 961 CTCAGTGGAGATGCTTGGTGTGGGGATCTGGGTGAAGGGGGTTGAGTAGCGACTGCCTGGGAGATGGCTGTTAGTAGGTC 1041 TGTGCCTGGTGTCTGCCTCGCCATCCTGGGGTAAGGGGCAGAGAGAAGGACTTGTCTTATGTAGGGTGTGGTCAGCCTTG 1121 GGGCCTTACCTACCCAGTTCCATGATATTTCTTGCCCTGTTCCCCCTGGAATGTGCAGTGGGCCAGCTGAGAGTACGCCT 1201 TGAGGAGGGGGGATGAGGCCTTAATCTGGGAGGCCTATCCCCCTATCCCAGGCATCCCAGACGAGGACTGGCTGAGGCTA 1281 GGCGCTCTCATGATCCACCTGCCCCGGGAGGGCAGCGGGGAAGACAGAGAAAAGCAAACGCATTCCTCCTCAGCTCCACC 1361 CACCTGGAGACGAATGTAGCCAGAGAGGAGGAAGGAGGGAAACTGAAGACACCGTGGCCCCTCGGCCTTCTCTCTGCTAG 1441 AGTTGCCGCTCAGAGGCTTCAGCCTGACTTCCAGCGGTCCCAAGAACACCTACTAATTCCTCTGCACTCCTTCATGGCTG 1521 GGACAGTTACTGGTTCATATGCAAGTAAAGATGACAATTTACTCAACAAATATTTATCGAGCACCTTTTATGTACCAGGC 1601 ACTGTTGTAGGTGCTTAGGATATTCTCATGTTTCTGAGGGATTACAGCCTGGGAGGATTCCACCGATCTTCACTTCTAGC 1681 AGGTTTTTTAAACGTGACCCTTGGCTGTATTTCCCATCTTCACAGTTCAAGCACCCCAAACCTGCCCTTTCTCCCCTGCA 1761 GACTGGCAGGTGGGATTGGCTCCCAGGTCATTTCCTCTCTCTCTCTTTCTCCCAAGCCTTTCTCCCTCCACAGGAAACAG 1841 ATTTTTCAGGGCCTTCCATGCCTGCCACTTTGTCCGTCTCTTTTTTTTTTTTTAAAGTAATATTTTTTAGAAATACATGT 1921 AAAATACCAAGAAATAATGTCTGCGCCTCTGCCACCTCTCTCTCATCTCTTATTTCATAAAGCTGGCTCTTTATGTTGCT 2001 TTACATGCCTTAATATATGTTTTATGGAGATTATACATATTATAGATCTATATATGTAATATATTTGTTTGGATGTCTGA 2081 TCTTTTCCTACAGTTCCTGCCCAGGCCTGTTTTTCTCTCCCTTATTTTCCACATCATTCCTAGCATATCAAGACCATACC 2161 CCTTGCCTTTTTGATCCAAAGAAGGGGAGAGGAAAGACTTATTTTAAGACATCTATTTTATGCTTTTGTTTAAAAAAAGC 2241 AAATCTATTTTCAAATTGTGCAATGTCTGAATGGAATTGGCAAATGAGGTGAGGAGATGGGGTAACTGCCTTTAGGTCCC 2321 AACCCTGTGCCTGTCCCTCTGCCACAGTGGCTTCCTTCCATCCTATTCCCCAGTCACGAAAGGGCTGGTCCCCAGAGCTC 2401 ACCCAGAAAGCATCTTGCCGGGGGCAGGGCATTCCCTCGGAAGTCCTGGCCTAAGGATTTTATTACACTGTCTGCTCCTG 2481 ATGACCCTCTGCGGTTGTCAGGCGTGAATCCTCTGGAAGGAACTGTTTGCAGTTGTATGCACAAAGGAGACCCATGCAGG 2561 CATGCACCCCAGATGGGCTGCTAGACTACCCCTCTTCATCAGCCTGCTGGAAAGAGCAGACAGCGTAACAGCAGCCTATG 2641 CCAAACAGCACTAAGGATGTCAGTGTACGAGACGGTGCGAAGCCCAGAGGAGGCGGCTTGGGATCCTCTGGGCCATCCCT 2721 GGCCCTGTAGCACAGACACATACAAGTTCCTTGGACTTGTCACACTCCTTTTCACTTGATCCCTCTCTGGCCTGGGTCAC 2801 ATTTATGACATCCCCCCTCTGCAACCTTTCTCTCTGGGGGCTGTACCAAAGGCATGGTACCTCAGTCTGGTATCCAGACT 2881 GTGAAATCAGCCTCTGGGCCAAGGAGGGTCCTACAGACAAGGTGGCATCTCAACCTCACCCAAGAAACCCCCGGGACTTT 2961 ACCCCAGCAGGCTGCCACTGGGGCACCGAACTAAGCCAGCTCAGCCTTCCAAGCTGCTTAGCCTTTGTCAACCATCAAAG 3041 TGGGGAAAGGGTCTCTGGCCTTGCAAGGATTTGGGCAGGATGGAAGTCTTTGTCTAGGTCTGAAATCAAGGGCTTGGGAA 3121 TCTAGAGCAGAGCTCCTGGCCAGCGTTTGAAGCCTGGCCTCCCACCTGGGGCATTTACTGACACCCTGTCGCCAGCCTAG 3201 AACATCCTGCTCTGAATGAACAGAGCCCAGATGGGGGTCCAGAGCTAAGTGACCCACCTGGGGAAGCTCTGATTATTCAT 3281 CCAGGGCCTTCTCAATGAGCACATTACCTCCATGATCAATAACCAAGAGGCTGCAGTCAAATACTGCTACTGTCACTTTG 3361 AAGATTTTCTAAGGGCACAAGTGGCACACTTGCTCTCCGGCCTTTGGGAGAGGCATGTTCTTGGGCAGGGCTGGCTACGG 3441 CAAGAGGGAACCAATTCCTTTCCCCTTTAGGCACCCTCTACCTGGCAGCTCTTAAAACTAAGAAAAAATATGATATACAC 3521 ACACATTATATATATATATATATATACACACACACACACACACACACGTATATCTATTTATGCACATATTGGGGCCAATT 3601 TGATTTGCTAGTATTAGACAATAAACTGTACAAGGAAATTTATTATCTCAGTGTCTTTATTTAGCATAAAAGTGGCCTTA 3681 GAAGAAGGGTGAAGGTTAGATAGATGGAATCTCTGTCAGGGGACAAACAGCTGTAGCATCCCCTTAGCATCTTTCTAGCC 3761 AATGAGCCCCCTCCCCAGGAGGAGGGATGGCCTGACTGAAACAGGTGAGAGTTTGCTTCCCCCTTTCAGCAGCATTCTTT 3841 TTAGATTTAGGTACTGAAGAATCCCAGTGAGTTCTGCATTTGTATCTTGCAAGTTTGTATAAACCCAATACAGGAAATAA 3921 AATGAATGGTTTGTATAAAAAAAAAAAAAAAAAAAAA Target sites
Provided by authors
Predicted by miRanda
DRVs
SNPs
DRVs & SNPs
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miRNA-target interactions (Predicted by miRanda) |
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DRVs in gene 3'UTRs | |||||||||||||||||||||
SNPs in gene 3'UTRs |
Experimental Support 1 for Functional miRNA-Target Interaction | |||||||
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miRNA:Target | ---- | ||||||
Validation Method |
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Conditions | hESCs (WA-09) | ||||||
Disease | 22874.0 | ||||||
Location of target site | 3'UTR | ||||||
Tools used in this research | TargetScan , miRTarCLIP , Piranha | ||||||
Original Description (Extracted from the article) |
...
"PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine
... - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development. |
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miRNA-target interactions (Provided by authors) |
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Article |
- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al. - Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
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Experimental Support 2 for Functional miRNA-Target Interaction | |
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miRNA:Target | ---- |
Validation Method |
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Conditions | HCT116 |
Location of target site | 3'UTR |
Tools used in this research | TargetScan , miRTarCLIP , Piranha |
Original Description (Extracted from the article) |
...
PAR-CLIP data was present in ERX177615. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_3_5
PAR-CLIP data was present in ERX177627. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_4_5
PAR-CLIP data was present in ERX177599. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_2_1
PAR-CLIP data was present in ERX177603. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_2_5
PAR-CLIP data was present in ERX177611. RNA binding protein: AGO2. Condition:p53_D_AGO_CLIP_3_1
... - Krell J; Stebbing J; Carissimi C; Dabrowska et al., 2016, Genome research. |
Article |
- Krell J; Stebbing J; Carissimi C; Dabrowska et al. - Genome research, 2016
DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing tumorigenesis. TP53 orchestrates these responses directly by transcriptionally modulating genes, including microRNAs (miRNAs), and by regulating miRNA biogenesis through interacting with the DROSHA complex. However, whether the association between miRNAs and AGO2 is regulated following DNA damage is not yet known. Here, we show that, following DNA damage, TP53 interacts with AGO2 to induce or reduce AGO2's association of a subset of miRNAs, including multiple let-7 family members. Furthermore, we show that specific mutations in TP53 decrease rather than increase the association of let-7 family miRNAs, reducing their activity without preventing TP53 from interacting with AGO2. This is consistent with the oncogenic properties of these mutants. Using AGO2 RIP-seq and PAR-CLIP-seq, we show that the DNA damage-induced increase in binding of let-7 family members to the RISC complex is functional. We unambiguously determine the global miRNA-mRNA interaction networks involved in the DNA damage response, validating them through the identification of miRNA-target chimeras formed by endogenous ligation reactions. We find that the target complementary region of the let-7 seed tends to have highly fixed positions and more variable ones. Additionally, we observe that miRNAs, whose cellular abundance or differential association with AGO2 is regulated by TP53, are involved in an intricate network of regulatory feedback and feedforward circuits. TP53-mediated regulation of AGO2-miRNA interaction represents a new mechanism of miRNA regulation in carcinogenesis.
LinkOut: [PMID: 26701625]
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CLIP-seq Support 1 for dataset SRR359787 | |
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Method / RBP | PAR-CLIP / AGO2 |
Cell line / Condition | hESCs (WA-09) / 4-thiouridine, RNase T1 |
Location of target site | ENST00000272203.3 | 3UTR | UACACUGUCUGCUCCUGA |
Tools used in this analysis | TargetScan, miRTarCLIP, and Piranha |
Article / Accession Series | PMID: 22012620 / SRX103431 |
CLIP-seq Viewer | Link |
MiRNA-Target Expression Profile | |||||||
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MiRNA-Target Expression Profile (TCGA) | |||||||
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256 hsa-miR-4433a-3p Target Genes:
Functional analysis:
ID![]() |
Target | Description | Validation methods |
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Strong evidence | Less strong evidence | |||||||||||
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MIRT088097 | SEPT2 | septin 2 | ![]() |
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2 | 2 | ||||||
MIRT143134 | MGRN1 | mahogunin ring finger 1 | ![]() |
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2 | 2 | ||||||
MIRT153912 | NCOA3 | nuclear receptor coactivator 3 | ![]() |
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2 | 2 | ||||||
MIRT154894 | GNAS | GNAS complex locus | ![]() |
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2 | 4 | ||||||
MIRT200996 | ZNF805 | zinc finger protein 805 | ![]() |
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2 | 2 | ||||||
MIRT215729 | C5ORF51 | chromosome 5 open reading frame 51 | ![]() |
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2 | 10 | ||||||
MIRT235593 | POFUT1 | protein O-fucosyltransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT263250 | SGPL1 | sphingosine-1-phosphate lyase 1 | ![]() |
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2 | 2 | ||||||
MIRT317951 | CDC5L | cell division cycle 5 like | ![]() |
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2 | 4 | ||||||
MIRT325572 | HIATL1 | major facilitator superfamily domain containing 14B | ![]() |
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2 | 4 | ||||||
MIRT354739 | LSM3 | LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated | ![]() |
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2 | 2 | ||||||
MIRT444552 | UBE2D3 | ubiquitin conjugating enzyme E2 D3 | ![]() |
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2 | 4 | ||||||
MIRT446978 | SUSD5 | sushi domain containing 5 | ![]() |
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2 | 2 | ||||||
MIRT451036 | ZNF610 | zinc finger protein 610 | ![]() |
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2 | 2 | ||||||
MIRT451596 | TRPM7 | transient receptor potential cation channel subfamily M member 7 | ![]() |
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2 | 2 | ||||||
MIRT452025 | NLRP6 | NLR family pyrin domain containing 6 | ![]() |
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2 | 2 | ||||||
MIRT452594 | CA6 | carbonic anhydrase 6 | ![]() |
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2 | 2 | ||||||
MIRT452768 | TCEA3 | transcription elongation factor A3 | ![]() |
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2 | 4 | ||||||
MIRT452959 | ZNF844 | zinc finger protein 844 | ![]() |
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2 | 2 | ||||||
MIRT453191 | ACSF2 | acyl-CoA synthetase family member 2 | ![]() |
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2 | 2 | ||||||
MIRT453382 | RHD | Rh blood group D antigen | ![]() |
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2 | 2 | ||||||
MIRT453685 | CEBPD | CCAAT/enhancer binding protein delta | ![]() |
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2 | 2 | ||||||
MIRT455272 | DDX39B | DExD-box helicase 39B | ![]() |
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2 | 8 | ||||||
MIRT455346 | BAMBI | BMP and activin membrane bound inhibitor | ![]() |
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2 | 2 | ||||||
MIRT456494 | SERAC1 | serine active site containing 1 | ![]() |
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2 | 2 | ||||||
MIRT456585 | NID1 | nidogen 1 | ![]() |
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2 | 2 | ||||||
MIRT456888 | DDA1 | DET1 and DDB1 associated 1 | ![]() |
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2 | 2 | ||||||
MIRT457123 | APOLD1 | apolipoprotein L domain containing 1 | ![]() |
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2 | 2 | ||||||
MIRT457852 | ZNF324B | zinc finger protein 324B | ![]() |
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2 | 2 | ||||||
MIRT457987 | APAF1 | apoptotic peptidase activating factor 1 | ![]() |
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2 | 2 | ||||||
MIRT459278 | APOBEC3F | apolipoprotein B mRNA editing enzyme catalytic subunit 3F | ![]() |
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2 | 2 | ||||||
MIRT459625 | SLC25A33 | solute carrier family 25 member 33 | ![]() |
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2 | 2 | ||||||
MIRT459715 | SGK494 | uncharacterized serine/threonine-protein kinase SgK494 | ![]() |
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2 | 2 | ||||||
MIRT460057 | RPL22L1 | ribosomal protein L22 like 1 | ![]() |
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2 | 2 | ||||||
MIRT460182 | UNK | unkempt family zinc finger | ![]() |
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2 | 6 | ||||||
MIRT460288 | PDE11A | phosphodiesterase 11A | ![]() |
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2 | 2 | ||||||
MIRT460841 | EGF | epidermal growth factor | ![]() |
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2 | 4 | ||||||
MIRT460860 | TBC1D19 | TBC1 domain family member 19 | ![]() |
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2 | 2 | ||||||
MIRT461519 | EMC7 | ER membrane protein complex subunit 7 | ![]() |
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2 | 2 | ||||||
MIRT461729 | SLC27A1 | solute carrier family 27 member 1 | ![]() |
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2 | 4 | ||||||
MIRT461821 | SNAP23 | synaptosome associated protein 23 | ![]() |
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2 | 2 | ||||||
MIRT462066 | CCDC77 | coiled-coil domain containing 77 | ![]() |
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2 | 4 | ||||||
MIRT462084 | MSANTD2 | Myb/SANT DNA binding domain containing 2 | ![]() |
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2 | 2 | ||||||
MIRT462508 | MTFMT | mitochondrial methionyl-tRNA formyltransferase | ![]() |
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2 | 10 | ||||||
MIRT464239 | VCP | valosin containing protein | ![]() |
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2 | 2 | ||||||
MIRT465316 | TRAF5 | TNF receptor associated factor 5 | ![]() |
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2 | 2 | ||||||
MIRT466549 | TBL1XR1 | transducin beta like 1 X-linked receptor 1 | ![]() |
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2 | 2 | ||||||
MIRT467128 | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | ![]() |
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2 | 8 | ||||||
MIRT468091 | SHCBP1 | SHC binding and spindle associated 1 | ![]() |
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2 | 2 | ||||||
MIRT469630 | RAD21 | RAD21 cohesin complex component | ![]() |
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2 | 6 | ||||||
MIRT471097 | PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta | ![]() |
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2 | 2 | ||||||
MIRT472704 | MYBL1 | MYB proto-oncogene like 1 | ![]() |
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2 | 2 | ||||||
MIRT472830 | MTMR10 | myotubularin related protein 10 | ![]() |
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2 | 2 | ||||||
MIRT472872 | MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | ![]() |
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2 | 2 | ||||||
MIRT472895 | MTDH | metadherin | ![]() |
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2 | 2 | ||||||
MIRT473728 | MAPK1 | mitogen-activated protein kinase 1 | ![]() |
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2 | 2 | ||||||
MIRT473859 | MAP2K4 | mitogen-activated protein kinase kinase 4 | ![]() |
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2 | 2 | ||||||
MIRT474047 | LONRF1 | LON peptidase N-terminal domain and ring finger 1 | ![]() |
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2 | 2 | ||||||
MIRT474297 | LAMC1 | laminin subunit gamma 1 | ![]() |
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2 | 2 | ||||||
MIRT474658 | KLF13 | Kruppel like factor 13 | ![]() |
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2 | 2 | ||||||
MIRT475234 | IKZF3 | IKAROS family zinc finger 3 | ![]() |
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2 | 2 | ||||||
MIRT475500 | HSP90B1 | heat shock protein 90 beta family member 1 | ![]() |
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2 | 2 | ||||||
MIRT475742 | HERPUD1 | homocysteine inducible ER protein with ubiquitin like domain 1 | ![]() |
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2 | 4 | ||||||
MIRT475793 | HDGF | heparin binding growth factor | ![]() |
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2 | 2 | ||||||
MIRT477254 | ERGIC2 | ERGIC and golgi 2 | ![]() |
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2 | 2 | ||||||
MIRT478228 | DDX52 | DExD-box helicase 52 | ![]() |
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2 | 2 | ||||||
MIRT478393 | DCTN5 | dynactin subunit 5 | ![]() |
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2 | 2 | ||||||
MIRT478754 | CS | citrate synthase | ![]() |
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2 | 2 | ||||||
MIRT478827 | CRKL | CRK like proto-oncogene, adaptor protein | ![]() |
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2 | 4 | ||||||
MIRT480234 | C9orf41 | carnosine N-methyltransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT480597 | BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | ![]() |
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2 | 2 | ||||||
MIRT484121 | C14orf142 | GON7, KEOPS complex subunit homolog | ![]() |
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2 | 2 | ||||||
MIRT484689 | PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | ![]() |
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2 | 2 | ||||||
MIRT486331 | C11orf54 | chromosome 11 open reading frame 54 | ![]() |
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2 | 4 | ||||||
MIRT488599 | FAM3C | family with sequence similarity 3 member C | ![]() |
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2 | 8 | ||||||
MIRT488833 | MRRF | mitochondrial ribosome recycling factor | ![]() |
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2 | 2 | ||||||
MIRT492523 | RAB15 | RAB15, member RAS oncogene family | ![]() |
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2 | 4 | ||||||
MIRT493632 | HIC2 | HIC ZBTB transcriptional repressor 2 | ![]() |
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2 | 2 | ||||||
MIRT500026 | ABCF2 | ATP binding cassette subfamily F member 2 | ![]() |
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2 | 8 | ||||||
MIRT501075 | SMAD7 | SMAD family member 7 | ![]() |
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2 | 8 | ||||||
MIRT503094 | BTG2 | BTG anti-proliferation factor 2 | ![]() |
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2 | 4 | ||||||
MIRT503336 | MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | ![]() |
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2 | 2 | ||||||
MIRT505465 | STMN1 | stathmin 1 | ![]() |
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2 | 4 | ||||||
MIRT505726 | SERTAD3 | SERTA domain containing 3 | ![]() |
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2 | 4 | ||||||
MIRT509333 | MS4A4A | membrane spanning 4-domains A4A | ![]() |
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2 | 2 | ||||||
MIRT509978 | KCNMB1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 | ![]() |
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2 | 4 | ||||||
MIRT513068 | CHST6 | carbohydrate sulfotransferase 6 | ![]() |
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2 | 2 | ||||||
MIRT513446 | EMP1 | epithelial membrane protein 1 | ![]() |
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2 | 6 | ||||||
MIRT513736 | PSD3 | pleckstrin and Sec7 domain containing 3 | ![]() |
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2 | 4 | ||||||
MIRT513996 | CENPQ | centromere protein Q | ![]() |
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2 | 4 | ||||||
MIRT516538 | MIXL1 | Mix paired-like homeobox | ![]() |
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2 | 2 | ||||||
MIRT517606 | SAV1 | salvador family WW domain containing protein 1 | ![]() |
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2 | 2 | ||||||
MIRT518064 | CEP89 | centrosomal protein 89 | ![]() |
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2 | 2 | ||||||
MIRT518119 | RNMTL1 | mitochondrial rRNA methyltransferase 3 | ![]() |
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2 | 2 | ||||||
MIRT518325 | WDR92 | WD repeat domain 92 | ![]() |
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2 | 2 | ||||||
MIRT519048 | ABCB11 | ATP binding cassette subfamily B member 11 | ![]() |
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2 | 2 | ||||||
MIRT520972 | SPPL2A | signal peptide peptidase like 2A | ![]() |
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2 | 4 | ||||||
MIRT521359 | RPL35A | ribosomal protein L35a | ![]() |
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2 | 2 | ||||||
MIRT523359 | GTF3C6 | general transcription factor IIIC subunit 6 | ![]() |
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2 | 2 | ||||||
MIRT523801 | FAM63A | MINDY lysine 48 deubiquitinase 1 | ![]() |
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2 | 2 | ||||||
MIRT524622 | C7orf73 | short transmembrane mitochondrial protein 1 | ![]() |
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2 | 2 | ||||||
MIRT525550 | PHB2 | prohibitin 2 | ![]() |
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2 | 4 | ||||||
MIRT529709 | ZBTB49 | zinc finger and BTB domain containing 49 | ![]() |
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2 | 2 | ||||||
MIRT531605 | PLEKHA6 | pleckstrin homology domain containing A6 | ![]() |
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2 | 2 | ||||||
MIRT532387 | UMPS | uridine monophosphate synthetase | ![]() |
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2 | 2 | ||||||
MIRT534468 | SCD | stearoyl-CoA desaturase | ![]() |
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2 | 4 | ||||||
MIRT537546 | ETNK1 | ethanolamine kinase 1 | ![]() |
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2 | 2 | ||||||
MIRT541619 | C11orf31 | selenoprotein H | ![]() |
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2 | 2 | ||||||
MIRT548380 | ENPP5 | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) | ![]() |
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2 | 4 | ||||||
MIRT549523 | HDDC2 | HD domain containing 2 | ![]() |
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2 | 2 | ||||||
MIRT549774 | SOD2 | superoxide dismutase 2 | ![]() |
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2 | 2 | ||||||
MIRT550578 | SLC2A5 | solute carrier family 2 member 5 | ![]() |
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2 | 2 | ||||||
MIRT551498 | CENPN | centromere protein N | ![]() |
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2 | 4 | ||||||
MIRT552301 | ITGA3 | integrin subunit alpha 3 | ![]() |
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2 | 2 | ||||||
MIRT555400 | PPM1L | protein phosphatase, Mg2+/Mn2+ dependent 1L | ![]() |
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2 | 2 | ||||||
MIRT556399 | LUC7L | LUC7 like | ![]() |
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2 | 2 | ||||||
MIRT557047 | HOXB3 | homeobox B3 | ![]() |
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2 | 2 | ||||||
MIRT558072 | ERO1L | endoplasmic reticulum oxidoreductase 1 alpha | ![]() |
1 | 2 | |||||||
MIRT559659 | AHCYL2 | adenosylhomocysteinase like 2 | ![]() |
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2 | 2 | ||||||
MIRT561239 | ZNF354B | zinc finger protein 354B | ![]() |
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2 | 2 | ||||||
MIRT566899 | LRIG2 | leucine rich repeats and immunoglobulin like domains 2 | ![]() |
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2 | 2 | ||||||
MIRT568786 | FAM120B | family with sequence similarity 120B | ![]() |
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2 | 2 | ||||||
MIRT574014 | MRPL12 | mitochondrial ribosomal protein L12 | ![]() |
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2 | 2 | ||||||
MIRT574885 | Dnajc6 | DnaJ heat shock protein family (Hsp40) member C6 | ![]() |
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2 | 2 | ||||||
MIRT575243 | Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | ![]() |
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2 | 2 | ||||||
MIRT576194 | Vsig2 | V-set and immunoglobulin domain containing 2 | ![]() |
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2 | 2 | ||||||
MIRT576309 | Acbd7 | acyl-Coenzyme A binding domain containing 7 | ![]() |
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2 | 2 | ||||||
MIRT576484 | Lhx4 | LIM homeobox protein 4 | ![]() |
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2 | 3 | ||||||
MIRT576646 | Mill2 | MHC I like leukocyte 2 | ![]() |
1 | 1 | |||||||
MIRT576708 | Kras | Kirsten rat sarcoma viral oncogene homolog | ![]() |
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2 | 2 | ||||||
MIRT576855 | Socs6 | suppressor of cytokine signaling 6 | ![]() |
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2 | 2 | ||||||
MIRT576950 | Aldoa | aldolase A, fructose-bisphosphate | ![]() |
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2 | 2 | ||||||
MIRT617133 | ZNF556 | zinc finger protein 556 | ![]() |
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2 | 4 | ||||||
MIRT617928 | ZNF783 | zinc finger family member 783 | ![]() |
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2 | 2 | ||||||
MIRT618981 | MRPS16 | mitochondrial ribosomal protein S16 | ![]() |
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2 | 2 | ||||||
MIRT621100 | SIX3 | SIX homeobox 3 | ![]() |
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2 | 2 | ||||||
MIRT624537 | BROX | BRO1 domain and CAAX motif containing | ![]() |
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2 | 2 | ||||||
MIRT625663 | C2orf48 | chromosome 2 open reading frame 48 | ![]() |
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2 | 2 | ||||||
MIRT627059 | DCTN6 | dynactin subunit 6 | ![]() |
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2 | 2 | ||||||
MIRT628319 | CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin | ![]() |
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2 | 2 | ||||||
MIRT630859 | ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | ![]() |
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2 | 2 | ||||||
MIRT632295 | TMEM65 | transmembrane protein 65 | ![]() |
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2 | 2 | ||||||
MIRT634115 | ZNF207 | zinc finger protein 207 | ![]() |
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2 | 2 | ||||||
MIRT634736 | CYP20A1 | cytochrome P450 family 20 subfamily A member 1 | ![]() |
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2 | 2 | ||||||
MIRT635655 | NDST3 | N-deacetylase and N-sulfotransferase 3 | ![]() |
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2 | 2 | ||||||
MIRT635772 | PDCL3 | phosducin like 3 | ![]() |
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2 | 2 | ||||||
MIRT635911 | LILRA2 | leukocyte immunoglobulin like receptor A2 | ![]() |
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2 | 2 | ||||||
MIRT636365 | OGFRL1 | opioid growth factor receptor like 1 | ![]() |
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2 | 4 | ||||||
MIRT637251 | GLRX2 | glutaredoxin 2 | ![]() |
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2 | 2 | ||||||
MIRT638705 | FZD4 | frizzled class receptor 4 | ![]() |
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2 | 2 | ||||||
MIRT639640 | PREX2 | phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 | ![]() |
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2 | 2 | ||||||
MIRT639676 | PPEF2 | protein phosphatase with EF-hand domain 2 | ![]() |
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2 | 4 | ||||||
MIRT642267 | SMIM17 | small integral membrane protein 17 | ![]() |
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2 | 2 | ||||||
MIRT642372 | ZNF581 | zinc finger protein 581 | ![]() |
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2 | 2 | ||||||
MIRT643545 | SLC25A17 | solute carrier family 25 member 17 | ![]() |
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2 | 2 | ||||||
MIRT647994 | PDE12 | phosphodiesterase 12 | ![]() |
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2 | 2 | ||||||
MIRT649094 | NOM1 | nucleolar protein with MIF4G domain 1 | ![]() |
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2 | 2 | ||||||
MIRT650993 | ZNF770 | zinc finger protein 770 | ![]() |
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2 | 2 | ||||||
MIRT651956 | UBE2N | ubiquitin conjugating enzyme E2 N | ![]() |
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2 | 2 | ||||||
MIRT652977 | SUN2 | Sad1 and UNC84 domain containing 2 | ![]() |
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2 | 2 | ||||||
MIRT654389 | RBM12B | RNA binding motif protein 12B | ![]() |
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2 | 2 | ||||||
MIRT655637 | OLFML2A | olfactomedin like 2A | ![]() |
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2 | 2 | ||||||
MIRT655729 | NRXN3 | neurexin 3 | ![]() |
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2 | 2 | ||||||
MIRT658171 | FCHSD1 | FCH and double SH3 domains 1 | ![]() |
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2 | 2 | ||||||
MIRT660937 | ACOX1 | acyl-CoA oxidase 1 | ![]() |
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2 | 2 | ||||||
MIRT662112 | CERKL | ceramide kinase like | ![]() |
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2 | 2 | ||||||
MIRT662302 | MPV17L | MPV17 mitochondrial inner membrane protein like | ![]() |
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2 | 2 | ||||||
MIRT662993 | TMEM59 | transmembrane protein 59 | ![]() |
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2 | 2 | ||||||
MIRT663071 | SFR1 | SWI5 dependent homologous recombination repair protein 1 | ![]() |
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2 | 2 | ||||||
MIRT663704 | ABHD17B | abhydrolase domain containing 17B | ![]() |
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2 | 2 | ||||||
MIRT663864 | MUC20 | mucin 20, cell surface associated | ![]() |
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2 | 2 | ||||||
MIRT665185 | HAUS5 | HAUS augmin like complex subunit 5 | ![]() |
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2 | 4 | ||||||
MIRT665402 | WEE1 | WEE1 G2 checkpoint kinase | ![]() |
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2 | 2 | ||||||
MIRT665688 | TNPO3 | transportin 3 | ![]() |
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2 | 2 | ||||||
MIRT665795 | TMEM170A | transmembrane protein 170A | ![]() |
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2 | 2 | ||||||
MIRT665847 | TIAL1 | TIA1 cytotoxic granule associated RNA binding protein like 1 | ![]() |
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2 | 2 | ||||||
MIRT666999 | PDPN | podoplanin | ![]() |
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2 | 2 | ||||||
MIRT667598 | LIPC | lipase C, hepatic type | ![]() |
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2 | 2 | ||||||
MIRT668576 | ELMSAN1 | ELM2 and Myb/SANT domain containing 1 | ![]() |
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2 | 4 | ||||||
MIRT670960 | UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT671187 | ZNF891 | zinc finger protein 891 | ![]() |
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2 | 2 | ||||||
MIRT671739 | ZNF451 | zinc finger protein 451 | ![]() |
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2 | 2 | ||||||
MIRT672745 | ZNF585B | zinc finger protein 585B | ![]() |
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2 | 4 | ||||||
MIRT673446 | ZNF583 | zinc finger protein 583 | ![]() |
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2 | 2 | ||||||
MIRT679843 | GPR75 | G protein-coupled receptor 75 | ![]() |
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2 | 2 | ||||||
MIRT680556 | ZNF584 | zinc finger protein 584 | ![]() |
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2 | 2 | ||||||
MIRT680661 | C1orf210 | chromosome 1 open reading frame 210 | ![]() |
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2 | 2 | ||||||
MIRT681285 | RFC2 | replication factor C subunit 2 | ![]() |
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2 | 2 | ||||||
MIRT683264 | ZNF329 | zinc finger protein 329 | ![]() |
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2 | 2 | ||||||
MIRT684519 | C1orf174 | chromosome 1 open reading frame 174 | ![]() |
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2 | 2 | ||||||
MIRT685065 | GEMIN4 | gem nuclear organelle associated protein 4 | ![]() |
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2 | 2 | ||||||
MIRT685157 | DTWD2 | DTW domain containing 2 | ![]() |
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2 | 2 | ||||||
MIRT685168 | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit | ![]() |
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2 | 2 | ||||||
MIRT685470 | CACNG8 | calcium voltage-gated channel auxiliary subunit gamma 8 | ![]() |
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2 | 2 | ||||||
MIRT686001 | NEK4 | NIMA related kinase 4 | ![]() |
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2 | 2 | ||||||
MIRT687027 | RNF24 | ring finger protein 24 | ![]() |
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2 | 2 | ||||||
MIRT687543 | MOB1B | MOB kinase activator 1B | ![]() |
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2 | 2 | ||||||
MIRT687592 | MANEAL | mannosidase endo-alpha like | ![]() |
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2 | 2 | ||||||
MIRT687753 | KIAA1328 | KIAA1328 | ![]() |
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2 | 2 | ||||||
MIRT688050 | GLUL | glutamate-ammonia ligase | ![]() |
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2 | 2 | ||||||
MIRT688374 | ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | ![]() |
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2 | 2 | ||||||
MIRT688802 | CBFA2T3 | CBFA2/RUNX1 translocation partner 3 | ![]() |
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2 | 2 | ||||||
MIRT688957 | ATXN3 | ataxin 3 | ![]() |
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2 | 2 | ||||||
MIRT689281 | C5AR2 | complement component 5a receptor 2 | ![]() |
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2 | 2 | ||||||
MIRT689988 | NNMT | nicotinamide N-methyltransferase | ![]() |
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2 | 2 | ||||||
MIRT689997 | MMP17 | matrix metallopeptidase 17 | ![]() |
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2 | 2 | ||||||
MIRT690014 | LUZP2 | leucine zipper protein 2 | ![]() |
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2 | 2 | ||||||
MIRT690161 | ELP3 | elongator acetyltransferase complex subunit 3 | ![]() |
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2 | 2 | ||||||
MIRT690379 | ZSWIM7 | zinc finger SWIM-type containing 7 | ![]() |
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2 | 2 | ||||||
MIRT690563 | MICA | MHC class I polypeptide-related sequence A | ![]() |
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2 | 2 | ||||||
MIRT691891 | EVC | EvC ciliary complex subunit 1 | ![]() |
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2 | 2 | ||||||
MIRT693107 | SCNM1 | sodium channel modifier 1 | ![]() |
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2 | 2 | ||||||
MIRT693832 | ZFP64 | ZFP64 zinc finger protein | ![]() |
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2 | 2 | ||||||
MIRT694105 | ZNF446 | zinc finger protein 446 | ![]() |
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2 | 2 | ||||||
MIRT694179 | ZNF486 | zinc finger protein 486 | ![]() |
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2 | 2 | ||||||
MIRT694475 | LRTOMT | leucine rich transmembrane and O-methyltransferase domain containing | ![]() |
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2 | 2 | ||||||
MIRT694998 | GGA2 | golgi associated, gamma adaptin ear containing, ARF binding protein 2 | ![]() |
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2 | 2 | ||||||
MIRT695031 | ALG10B | ALG10B, alpha-1,2-glucosyltransferase | ![]() |
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2 | 2 | ||||||
MIRT695163 | TCTN2 | tectonic family member 2 | ![]() |
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2 | 2 | ||||||
MIRT695525 | SLC25A34 | solute carrier family 25 member 34 | ![]() |
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2 | 2 | ||||||
MIRT696067 | ZNF264 | zinc finger protein 264 | ![]() |
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2 | 2 | ||||||
MIRT696616 | CRIPT | CXXC repeat containing interactor of PDZ3 domain | ![]() |
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2 | 2 | ||||||
MIRT696661 | AGXT2 | alanine--glyoxylate aminotransferase 2 | ![]() |
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2 | 2 | ||||||
MIRT696705 | PNPO | pyridoxamine 5'-phosphate oxidase | ![]() |
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2 | 2 | ||||||
MIRT697173 | INMT | indolethylamine N-methyltransferase | ![]() |
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2 | 2 | ||||||
MIRT697303 | ZNF652 | zinc finger protein 652 | ![]() |
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2 | 2 | ||||||
MIRT697491 | ZBTB8B | zinc finger and BTB domain containing 8B | ![]() |
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2 | 2 | ||||||
MIRT698657 | TERF2 | telomeric repeat binding factor 2 | ![]() |
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2 | 2 | ||||||
MIRT699042 | SOAT1 | sterol O-acyltransferase 1 | ![]() |
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2 | 2 | ||||||
MIRT699185 | SLX4IP | SLX4 interacting protein | ![]() |
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2 | 2 | ||||||
MIRT699598 | SHOC2 | SHOC2, leucine rich repeat scaffold protein | ![]() |
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2 | 2 | ||||||
MIRT700150 | RNF115 | ring finger protein 115 | ![]() |
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2 | 2 | ||||||
MIRT700720 | PNO1 | partner of NOB1 homolog | ![]() |
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2 | 2 | ||||||
MIRT700870 | PER2 | period circadian clock 2 | ![]() |
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2 | 2 | ||||||
MIRT700912 | PDXK | pyridoxal kinase | ![]() |
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2 | 2 | ||||||
MIRT701095 | PAPOLG | poly(A) polymerase gamma | ![]() |
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2 | 2 | ||||||
MIRT701194 | OTUD3 | OTU deubiquitinase 3 | ![]() |
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2 | 2 | ||||||
MIRT702203 | LPP | LIM domain containing preferred translocation partner in lipoma | ![]() |
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2 | 2 | ||||||
MIRT702272 | LHX4 | LIM homeobox 4 | ![]() |
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2 | 3 | ||||||
MIRT703125 | GPRC5A | G protein-coupled receptor class C group 5 member A | ![]() |
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2 | 2 | ||||||
MIRT703252 | GNS | glucosamine (N-acetyl)-6-sulfatase | ![]() |
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2 | 2 | ||||||
MIRT703262 | GNL3L | G protein nucleolar 3 like | ![]() |
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2 | 2 | ||||||
MIRT703440 | FYTTD1 | forty-two-three domain containing 1 | ![]() |
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2 | 2 | ||||||
MIRT704321 | DCUN1D5 | defective in cullin neddylation 1 domain containing 5 | ![]() |
![]() |
2 | 2 | ||||||
MIRT704393 | CTSS | cathepsin S | ![]() |
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2 | 2 | ||||||
MIRT704483 | CPT1A | carnitine palmitoyltransferase 1A | ![]() |
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2 | 2 | ||||||
MIRT704880 | CCSER2 | coiled-coil serine rich protein 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT704926 | CCDC36 | coiled-coil domain containing 36 | ![]() |
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2 | 2 | ||||||
MIRT705175 | BZW1 | basic leucine zipper and W2 domains 1 | ![]() |
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2 | 2 | ||||||
MIRT706561 | EIF2AK2 | eukaryotic translation initiation factor 2 alpha kinase 2 | ![]() |
![]() |
2 | 2 | ||||||
MIRT707048 | TRPV2 | transient receptor potential cation channel subfamily V member 2 | ![]() |
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2 | 2 | ||||||
MIRT711497 | PGD | phosphogluconate dehydrogenase | ![]() |
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2 | 2 | ||||||
MIRT716644 | EPGN | epithelial mitogen | ![]() |
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2 | 2 | ||||||
MIRT720083 | TNRC6B | trinucleotide repeat containing 6B | ![]() |
![]() |
2 | 2 | ||||||
MIRT722288 | PMPCA | peptidase, mitochondrial processing alpha subunit | ![]() |
![]() |
2 | 2 | ||||||
MIRT725468 | GRAP2 | GRB2-related adaptor protein 2 | ![]() |
![]() |
2 | 2 |
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