miRTarBase - #MIRT531608


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pre-miRNA Information
pre-miRNA hsa-mir-6868   
Genomic Coordinates chr17: 76098019 - 76098076
Description Homo sapiens miR-6868 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6868-3p
Sequence 38| UUCCUUCUGUUGUCUGUGCAG |58
Evidence Experimental
Experiments Meta-analysis
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM4415890 16 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1268215934 1 dbSNP
rs199573454 9 dbSNP
rs893365109 12 dbSNP
rs370367037 13 dbSNP
rs7208391 16 dbSNP
rs752026363 19 dbSNP
rs113525369 20 dbSNP
Putative Targets

Gene Information
Gene Symbol ACP1   
Synonyms HAAP, LMW-PTP, LMWPTP
Description acid phosphatase 1, soluble
Transcript NM_004300   
Other Transcripts NM_001040649 , NM_007099   
Expression
Putative miRNA Targets on ACP1
3'UTR of ACP1
(miRNA target sites are highlighted)		 
>ACP1|NM_004300|3'UTR
   1 GGCAGGTTCGTGCCCTGCTGCGGCCAGCCTGACTAGACCCCACCCTGAGGTCCTGCATTTCTCAGTCGGTGTGTAATCAC
  81 GTTCCAGGGCCCAAAGCCCAGCTCTTTGTTCAGTTGACTTACTGTTTCTTACCTTAAAAAGTAATTGTAGATGGAAATCA
 161 GTTGTGTTTGGCAGGAGAATCAATAAAAATCTTTGATTCAGACAGCTTATGGGGTATTTTAAGCATTCTTAGACTAGTTG
 241 AACATCTCACTTTGCCCCAGTTACAAAAATAGTAGAACAAGCAACATAAAACAATGAAGGAAAACCTCACTTGAAGGCCC
 321 AGGTCAACATCTAAGCCTGTTGAGACTTAGATAATCGAGTCTACCTCTTCAGTAGGTTTGTGTGGATGGCCTGGAGGGCA
 401 GGTGCCCTCTGCTCCCCAGTGCTACCTCTCTCTTCCCTAGGGCCTTTTGTGGATTGACAGTAGTCCCCTCCGTAGGAGCT
 481 CACAGTCTAGATTAGAAGTGTTTTAATTTCTACACACCCATAGTGCACACTTGTATATTGAAAAGATAGGGAAGAGAGAA
 561 ACATTTATGGAATCAGTCGTTGGCACCTTCAATACTTCATGATTTTTGTCGAGTTTACTTCATGAGGAGGTCAGCCCATT
 641 GGCTCCCATCTGAACCACTTTGCCTCTGAAACTTAATTACATCCAGAAAGAAGGACACTTGTATGCTAGTCTATGGTCAG
 721 TTGAGGAATATGACTGTTTTTATATGCACATGTAACCCAAATGTCCAATATAAATTGGCTTATTTTTTAAAATAATTTTA
 801 AAAGTTGGGAAAAGTGTTATTATTTGGCATGCTTAAATATTGAATAAGTATTCTTCATCAGCATTTAATAAATGTATAGG
 881 CAGATGTAAGGTAATTTCTGTGTATTTTGAGATAATGTCAAAATCATGAATATTTCAAAATAAACTGGGGAGTTATAAAA
 961 ATACAACTAGAGATATAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gacGUGUCUGU-UGUCUUCCUu 5'
             :|||  || | ||||||| 
Target 5' aatTACATCCAGAAAGAAGGAc 3'
 675 - 696 154.00 -12.10
2 
miRNA  3' gaCG-UGUCUGUUG-U-CUUCCUu 5'
            || ||| | ||| | |||||| 
Target 5' aaGCAACATAAAACAATGAAGGAa 3'
 279 - 302 131.00 -14.20
3 
miRNA  3' gacGUGUC---UGUUGUCUUCcuu 5'
             |||||   | | :|||||   
Target 5' gctCACAGTCTAGATTAGAAGtgt 3'
 478 - 501 118.00 -12.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31661052 4 COSMIC
COSN30460883 10 COSMIC
COSN28791718 11 COSMIC
COSN31511493 32 COSMIC
COSN30452651 41 COSMIC
COSN31557215 58 COSMIC
COSN30100997 59 COSMIC
COSN31501358 64 COSMIC
COSN30109428 65 COSMIC
COSN26964877 69 COSMIC
COSN30450680 69 COSMIC
COSN30504213 70 COSMIC
COSN30510341 106 COSMIC
COSN30531252 141 COSMIC
COSN2382271 151 COSMIC
COSN32057399 171 COSMIC
COSN1082793 192 COSMIC
COSN32063314 516 COSMIC
COSN1834626 521 COSMIC
COSN9998247 593 COSMIC
COSN21331865 663 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1271238786 2 dbSNP
rs1259834543 3 dbSNP
rs1350372316 8 dbSNP
rs547572404 10 dbSNP
rs77927634 11 dbSNP
rs1490004042 14 dbSNP
rs746666231 19 dbSNP
rs768110291 20 dbSNP
rs529906639 22 dbSNP
rs116833857 23 dbSNP
rs1363503621 24 dbSNP
rs1387472263 25 dbSNP
rs1042064742 36 dbSNP
rs770303461 41 dbSNP
rs773656331 44 dbSNP
rs763395204 45 dbSNP
rs201887597 47 dbSNP
rs774650894 49 dbSNP
rs759869670 51 dbSNP
rs767447123 52 dbSNP
rs1413169123 56 dbSNP
rs903553360 68 dbSNP
rs1000620127 69 dbSNP
rs1459465670 81 dbSNP
rs370285099 82 dbSNP
rs889612434 87 dbSNP
rs1306295047 90 dbSNP
rs1008076100 95 dbSNP
rs1329516620 102 dbSNP
rs1267289174 103 dbSNP
rs187801608 104 dbSNP
rs192286578 105 dbSNP
rs1019517165 110 dbSNP
rs570551762 115 dbSNP
rs1437268231 116 dbSNP
rs1370116094 117 dbSNP
rs776078992 126 dbSNP
rs961284736 129 dbSNP
rs1318051034 132 dbSNP
rs534371055 138 dbSNP
rs1410681101 140 dbSNP
rs1310150042 147 dbSNP
rs1460252540 154 dbSNP
rs1395279350 158 dbSNP
rs1426823340 163 dbSNP
rs1172858189 167 dbSNP
rs972694550 171 dbSNP
rs1392729824 178 dbSNP
rs1026978971 180 dbSNP
rs1323452102 183 dbSNP
rs1213344412 185 dbSNP
rs1241493254 185 dbSNP
rs1130642 192 dbSNP
rs1443987814 199 dbSNP
rs952860972 203 dbSNP
rs1273284775 210 dbSNP
rs371196535 215 dbSNP
rs980192176 218 dbSNP
rs184583212 265 dbSNP
rs1347197528 271 dbSNP
rs1342334386 274 dbSNP
rs188948556 276 dbSNP
rs1270194357 281 dbSNP
rs927383616 282 dbSNP
rs1361272192 292 dbSNP
rs938829850 294 dbSNP
rs1433744000 295 dbSNP
rs1373041925 300 dbSNP
rs1169911593 301 dbSNP
rs1449581120 303 dbSNP
rs1206853062 318 dbSNP
rs1418693667 322 dbSNP
rs1255014356 329 dbSNP
rs535648696 341 dbSNP
rs772125300 345 dbSNP
rs557258716 347 dbSNP
rs1181663651 348 dbSNP
rs1257433193 350 dbSNP
rs913453194 351 dbSNP
rs946297052 353 dbSNP
rs1308212804 354 dbSNP
rs1295417471 357 dbSNP
rs1166731453 364 dbSNP
rs1213329728 365 dbSNP
rs1389616793 366 dbSNP
rs1430555936 372 dbSNP
rs1170681993 373 dbSNP
rs1285176249 392 dbSNP
rs377219203 392 dbSNP
rs796732564 392 dbSNP
rs903502154 398 dbSNP
rs1266403763 399 dbSNP
rs1309539131 403 dbSNP
rs11553744 412 dbSNP
rs1446952148 419 dbSNP
rs759069743 420 dbSNP
rs1429766132 426 dbSNP
rs372423370 426 dbSNP
rs575516219 427 dbSNP
rs73146287 428 dbSNP
rs1168189570 436 dbSNP
rs1407040420 437 dbSNP
rs1414508674 441 dbSNP
rs1186923917 445 dbSNP
rs1474143115 450 dbSNP
rs1255651148 458 dbSNP
rs1184628534 459 dbSNP
rs1480962146 460 dbSNP
rs1381167837 463 dbSNP
rs1250860950 464 dbSNP
rs1202972348 465 dbSNP
rs773479583 466 dbSNP
rs1049460202 467 dbSNP
rs889556908 472 dbSNP
rs181321851 473 dbSNP
rs1333168824 479 dbSNP
rs1230041812 484 dbSNP
rs1289763723 484 dbSNP
rs1277691770 492 dbSNP
rs1371927946 494 dbSNP
rs1040905373 510 dbSNP
rs897024182 512 dbSNP
rs573297307 516 dbSNP
rs1459622633 524 dbSNP
rs1413909033 531 dbSNP
rs994095804 532 dbSNP
rs765679656 534 dbSNP
rs1256967305 535 dbSNP
rs1175520250 536 dbSNP
rs747057356 539 dbSNP
rs1254158056 540 dbSNP
rs775984919 545 dbSNP
rs1247992592 560 dbSNP
rs1027338954 563 dbSNP
rs1240275732 576 dbSNP
rs1315928935 579 dbSNP
rs374774369 579 dbSNP
rs776930773 580 dbSNP
rs1220442337 584 dbSNP
rs1414122940 587 dbSNP
rs1371107669 588 dbSNP
rs1325061529 593 dbSNP
rs1438661266 596 dbSNP
rs952714945 598 dbSNP
rs1001960562 602 dbSNP
rs759616896 611 dbSNP
rs1452836830 612 dbSNP
rs55951179 613 dbSNP
rs1363431041 618 dbSNP
rs765635707 622 dbSNP
rs1434916690 624 dbSNP
rs540413467 629 dbSNP
rs960123311 633 dbSNP
rs775709863 644 dbSNP
rs12503 648 dbSNP
rs1250486378 665 dbSNP
rs1389321152 672 dbSNP
rs1206086721 674 dbSNP
rs1436597869 675 dbSNP
rs562161017 676 dbSNP
rs1258525065 677 dbSNP
rs1272578628 679 dbSNP
rs1211802509 682 dbSNP
rs1366399179 684 dbSNP
rs913402260 685 dbSNP
rs1303040316 686 dbSNP
rs1314276845 688 dbSNP
rs6855 692 dbSNP
rs14814 697 dbSNP
rs1367226722 700 dbSNP
rs1296289140 702 dbSNP
rs1381424464 714 dbSNP
rs764357173 717 dbSNP
rs1382521813 719 dbSNP
rs567043223 737 dbSNP
rs1465767446 749 dbSNP
rs1210594068 753 dbSNP
rs542031973 759 dbSNP
rs936325738 774 dbSNP
rs1049862409 780 dbSNP
rs1191964561 783 dbSNP
rs563593642 789 dbSNP
rs527943327 802 dbSNP
rs1471461631 811 dbSNP
rs1260120345 813 dbSNP
rs1158191316 814 dbSNP
rs1389203147 815 dbSNP
rs547024668 817 dbSNP
rs943761269 823 dbSNP
rs1040855293 831 dbSNP
rs1251757299 833 dbSNP
rs1226646218 835 dbSNP
rs1324422827 843 dbSNP
rs60700010 845 dbSNP
rs994434578 850 dbSNP
rs1436621019 851 dbSNP
rs1312564936 854 dbSNP
rs1432881993 860 dbSNP
rs1398735012 862 dbSNP
rs1168956173 872 dbSNP
rs1294898683 874 dbSNP
rs1456671669 877 dbSNP
rs1461939718 878 dbSNP
rs1048285315 886 dbSNP
rs367597593 887 dbSNP
rs1001509690 902 dbSNP
rs1034306171 905 dbSNP
rs878868775 909 dbSNP
rs1483710896 912 dbSNP
rs570309963 931 dbSNP
rs1330350674 939 dbSNP
rs1337332626 945 dbSNP
rs1225956582 949 dbSNP
rs528078264 950 dbSNP
rs1451091267 951 dbSNP
rs1413203851 957 dbSNP
rs1337557985 959 dbSNP
rs1329593526 964 dbSNP
rs546334865 977 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 52.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gacgugucuguuguCUUCCUu 5'
                        |||||| 
Target 5' ------------cuGAAGGAa 3'
 		1 - 9
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000272067.6 | 3UTR | CUGAAGGAAGUUUGAGGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
178 hsa-miR-6868-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT107800 SLC1A1 solute carrier family 1 member 1 2 2
MIRT164443 CPEB2 cytoplasmic polyadenylation element binding protein 2 2 2
MIRT180168 NOTCH2 notch 2 2 2
MIRT363961 IMPAD1 inositol monophosphatase domain containing 1 2 2
MIRT445561 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT468817 RSRC2 arginine and serine rich coiled-coil 2 2 4
MIRT475452 HSPA8 heat shock protein family A (Hsp70) member 8 2 6
MIRT478206 DDX6 DEAD-box helicase 6 2 2
MIRT506235 PEX13 peroxisomal biogenesis factor 13 2 4
MIRT507651 CREBRF CREB3 regulatory factor 2 4
MIRT509448 CAPRIN1 cell cycle associated protein 1 2 4
MIRT520196 WASL Wiskott-Aldrich syndrome like 2 2
MIRT521020 SLC38A1 solute carrier family 38 member 1 2 4
MIRT526334 SH3TC2 SH3 domain and tetratricopeptide repeats 2 2 2
MIRT527175 LRRTM4 leucine rich repeat transmembrane neuronal 4 2 2
MIRT527348 FAM69C family with sequence similarity 69 member C 2 2
MIRT527514 FOXB1 forkhead box B1 2 4
MIRT527955 MTAP methylthioadenosine phosphorylase 2 2
MIRT528474 STAMBPL1 STAM binding protein like 1 2 2
MIRT528929 SFMBT2 Scm like with four mbt domains 2 2 2
MIRT531496 NONO non-POU domain containing octamer binding 2 2
MIRT531608 ACP1 acid phosphatase 1, soluble 2 2
MIRT535579 NUP35 nucleoporin 35 2 2
MIRT536158 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 6
MIRT536194 MAML2 mastermind like transcriptional coactivator 2 2 2
MIRT549649 RSL1D1 ribosomal L1 domain containing 1 2 2
MIRT551819 TMEM138 transmembrane protein 138 2 2
MIRT557174 HOXA11 homeobox A11 2 2
MIRT558889 CCND2 cyclin D2 2 2
MIRT559109 C16orf52 chromosome 16 open reading frame 52 2 2
MIRT569341 EFHC1 EF-hand domain containing 1 2 2
MIRT608169 ERBB2 erb-b2 receptor tyrosine kinase 2 2 2
MIRT609642 PACS2 phosphofurin acidic cluster sorting protein 2 2 2
MIRT610274 PLCXD3 phosphatidylinositol specific phospholipase C X domain containing 3 2 2
MIRT611130 CTBP2 C-terminal binding protein 2 2 2
MIRT611350 KIAA2018 upstream transcription factor family member 3 2 2
MIRT612894 HMGB1 high mobility group box 1 2 2
MIRT613291 BACE2 beta-site APP-cleaving enzyme 2 2 4
MIRT614162 MYO1F myosin IF 2 2
MIRT614217 TSKU tsukushi, small leucine rich proteoglycan 2 2
MIRT615474 RPS6KA3 ribosomal protein S6 kinase A3 2 2
MIRT615863 HSPA6 heat shock protein family A (Hsp70) member 6 2 2
MIRT616022 PRRG4 proline rich and Gla domain 4 2 2
MIRT616349 RASGEF1B RasGEF domain family member 1B 2 2
MIRT616679 FJX1 four jointed box 1 2 2
MIRT616811 PAPPA-AS1 PAPPA antisense RNA 1 2 2
MIRT616964 LMX1A LIM homeobox transcription factor 1 alpha 2 2
MIRT617067 SPIB Spi-B transcription factor 2 2
MIRT618597 C2orf48 chromosome 2 open reading frame 48 2 2
MIRT618656 ATP6AP1L ATPase H+ transporting accessory protein 1 like 2 2
MIRT618914 KLHL4 kelch like family member 4 2 2
MIRT620197 VN1R1 vomeronasal 1 receptor 1 2 2
MIRT620644 CXCL5 C-X-C motif chemokine ligand 5 2 2
MIRT620762 CCR5 C-C motif chemokine receptor 5 (gene/pseudogene) 2 2
MIRT621142 RNF122 ring finger protein 122 2 2
MIRT621248 QTRT1 queuine tRNA-ribosyltransferase catalytic subunit 1 2 2
MIRT622711 PLEKHA2 pleckstrin homology domain containing A2 2 2
MIRT622941 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT623329 MAK16 MAK16 homolog 2 2
MIRT623539 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT624413 CCDC149 coiled-coil domain containing 149 2 2
MIRT624478 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT624574 BCL9L B-cell CLL/lymphoma 9 like 2 2
MIRT624584 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT624685 AR androgen receptor 2 2
MIRT625750 GPC5 glypican 5 2 2
MIRT626539 EMCN endomucin 2 2
MIRT627474 STRN striatin 2 2
MIRT628183 GLP1R glucagon like peptide 1 receptor 2 2
MIRT634165 XKR4 XK related 4 2 2
MIRT634553 LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2 2
MIRT637463 DEFB105B defensin beta 105B 2 4
MIRT637495 DEFB105A defensin beta 105A 2 4
MIRT638102 ZBTB7A zinc finger and BTB domain containing 7A 2 2
MIRT638313 RNF157 ring finger protein 157 2 2
MIRT639297 OPTN optineurin 2 2
MIRT639588 RGS5 regulator of G protein signaling 5 2 2
MIRT639721 RAB17 RAB17, member RAS oncogene family 2 2
MIRT640060 KPNA6 karyopherin subunit alpha 6 2 2
MIRT640117 DCAF7 DDB1 and CUL4 associated factor 7 2 2
MIRT640387 ZNF785 zinc finger protein 785 2 2
MIRT640579 MYO5A myosin VA 2 2
MIRT640591 TM9SF4 transmembrane 9 superfamily member 4 2 2
MIRT640627 ZFP30 ZFP30 zinc finger protein 2 2
MIRT640761 GLO1 glyoxalase I 2 2
MIRT640808 ZMAT1 zinc finger matrin-type 1 2 2
MIRT641827 TRIM71 tripartite motif containing 71 2 2
MIRT643955 GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2 2
MIRT644218 ADD1 adducin 1 2 2
MIRT644356 NDUFAF6 NADH:ubiquinone oxidoreductase complex assembly factor 6 2 2
MIRT644560 SPOP speckle type BTB/POZ protein 2 2
MIRT645486 TRIM63 tripartite motif containing 63 2 2
MIRT645595 MRPS15 mitochondrial ribosomal protein S15 2 2
MIRT645840 BRS3 bombesin receptor subtype 3 2 2
MIRT645944 TTF2 transcription termination factor 2 2 2
MIRT646154 VASH2 vasohibin 2 2 2
MIRT648097 LRRFIP1 LRR binding FLII interacting protein 1 2 2
MIRT648131 JAGN1 jagunal homolog 1 2 2
MIRT648469 TCERG1 transcription elongation regulator 1 2 2
MIRT648954 ZNF385D zinc finger protein 385D 2 4
MIRT649447 ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2 2
MIRT649559 POLD3 DNA polymerase delta 3, accessory subunit 2 2
MIRT649641 SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 2 2
MIRT650541 MSANTD2 Myb/SANT DNA binding domain containing 2 2 2
MIRT651104 ZNF48 zinc finger protein 48 2 2
MIRT651197 ZNF281 zinc finger protein 281 2 2
MIRT651682 VPS13D vacuolar protein sorting 13 homolog D 2 2
MIRT651995 UBA6 ubiquitin like modifier activating enzyme 6 2 2
MIRT652062 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT652310 TNRC6B trinucleotide repeat containing 6B 2 2
MIRT654265 RGS17 regulator of G protein signaling 17 2 2
MIRT654402 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT654679 PSMB5 proteasome subunit beta 5 2 2
MIRT654741 PRKCB protein kinase C beta 2 2
MIRT656172 MRPL44 mitochondrial ribosomal protein L44 2 2
MIRT656583 LSAMP limbic system-associated membrane protein 2 2
MIRT656700 LNPEP leucyl and cystinyl aminopeptidase 2 2
MIRT657492 HBEGF heparin binding EGF like growth factor 2 2
MIRT658487 EXOC7 exocyst complex component 7 2 2
MIRT658583 EPHB1 EPH receptor B1 2 2
MIRT658657 EMX2 empty spiracles homeobox 2 2 2
MIRT659123 DENND5B DENN domain containing 5B 2 2
MIRT659188 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT659329 CSNK2A1 casein kinase 2 alpha 1 2 2
MIRT660376 B4GALT6 beta-1,4-galactosyltransferase 6 2 2
MIRT660636 ANKRD50 ankyrin repeat domain 50 2 2
MIRT660689 ANAPC1 anaphase promoting complex subunit 1 2 4
MIRT662434 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT662562 IL2RA interleukin 2 receptor subunit alpha 2 2
MIRT662966 ZSWIM1 zinc finger SWIM-type containing 1 2 2
MIRT666429 SH2B3 SH2B adaptor protein 3 2 2
MIRT668902 CREB1 cAMP responsive element binding protein 1 2 2
MIRT673056 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT687429 NR3C1 nuclear receptor subfamily 3 group C member 1 2 2
MIRT694785 DHFRL1 dihydrofolate reductase 2 2 2
MIRT708677 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT708853 TMSB4X thymosin beta 4, X-linked 2 2
MIRT709605 CXorf23 BCLAF1 and THRAP3 family member 3 2 2
MIRT709993 IFIT1 interferon induced protein with tetratricopeptide repeats 1 2 2
MIRT710881 MTG1 mitochondrial ribosome associated GTPase 1 2 2
MIRT711023 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT711338 FMNL2 formin like 2 2 2
MIRT711351 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2 2
MIRT712163 SURF4 surfeit 4 2 2
MIRT712225 RIMS3 regulating synaptic membrane exocytosis 3 2 2
MIRT713028 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT713719 CD244 CD244 molecule 2 2
MIRT713970 ASIC4 acid sensing ion channel subunit family member 4 2 2
MIRT714872 SPDL1 spindle apparatus coiled-coil protein 1 2 2
MIRT715837 SZT2 SZT2, KICSTOR complex subunit 2 2
MIRT717031 KRTAP4-9 keratin associated protein 4-9 2 2
MIRT717158 SHB SH2 domain containing adaptor protein B 2 2
MIRT717292 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT717670 CDC42BPA CDC42 binding protein kinase alpha 2 2
MIRT717838 NEGR1 neuronal growth regulator 1 2 2
MIRT718148 TTC33 tetratricopeptide repeat domain 33 2 2
MIRT719726 SLC39A11 solute carrier family 39 member 11 2 2
MIRT719909 IL5 interleukin 5 2 2
MIRT720245 FAM83F family with sequence similarity 83 member F 2 2
MIRT720352 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT720803 NUDT5 nudix hydrolase 5 2 2
MIRT720930 PPP1R3E protein phosphatase 1 regulatory subunit 3E 2 2
MIRT721609 PPP1CB protein phosphatase 1 catalytic subunit beta 2 2
MIRT722090 SUSD1 sushi domain containing 1 2 2
MIRT722271 LURAP1 leucine rich adaptor protein 1 2 2
MIRT722548 FGFR1OP FGFR1 oncogene partner 2 2
MIRT723141 METTL24 methyltransferase like 24 2 2
MIRT723271 TAL2 TAL bHLH transcription factor 2 2 2
MIRT723396 OAF out at first homolog 2 2
MIRT723633 STK25 serine/threonine kinase 25 2 2
MIRT723680 CIRH1A UTP4, small subunit processome component 2 2
MIRT723803 BDKRB2 bradykinin receptor B2 2 2
MIRT723894 NUDT21 nudix hydrolase 21 2 2
MIRT724672 NCAPG non-SMC condensin I complex subunit G 2 2
MIRT724759 PSG4 pregnancy specific beta-1-glycoprotein 4 2 2
MIRT724973 TNS1 tensin 1 2 2
MIRT725046 ZFP36L1 ZFP36 ring finger protein like 1 2 2
MIRT725428 HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6868-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-6868-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-6868-3p Docetaxel+Cisplatin+5-Fluorouracil resistant tissue (hypopharyngeal squamous cell carcinoma)

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