miRTarBase - #MIRT531868


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pre-miRNA Information
pre-miRNA hsa-mir-635   
Genomic Coordinates chr17: 68424451 - 68424548
Synonyms MIRN635, hsa-mir-635, MIR635
Description Homo sapiens miR-635 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-635
Sequence 16| ACUUGGGCACUGAAACAAUGUCC |38
Evidence Experimental
Experiments SAGE
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30524107 5 COSMIC
COSN492359 18 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1431386008 2 dbSNP
rs1200120170 6 dbSNP
rs1477452388 8 dbSNP
rs765045345 10 dbSNP
rs761495041 14 dbSNP
rs1447802278 18 dbSNP
rs994692593 18 dbSNP
rs776535164 23 dbSNP
Putative Targets

Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B0Q4NY miR-635 Predictive Biomarker (PRD) Transcriptomic Data . . . .
Gene Information
Gene Symbol POF1B   
Synonyms POF, POF2B
Description premature ovarian failure, 1B
Transcript NM_024921   
Expression
Putative miRNA Targets on POF1B
3'UTR of POF1B
(miRNA target sites are highlighted)		 
>POF1B|NM_024921|3'UTR
   1 ATGGATCCACTTTAAAGTATTACAACTCAAAGCCGTTTTTTTTTTGTGTGTGTGTCTCTGCATTAGTACTTTGTTATTTT
  81 TCCATCACTAAAGGCCAATCAGAATTTGGAACCATGCTGCTACCCAAGAAATCTAATGGAATGAATTAGTTCTGTAGATG
 161 ACAATTTCTTCACCCATTTATGAGACCTAAATCTTTTCCATAACACTCATGTATTCAGTATAACAACATACTAACTGAAA
 241 GAGGGACCTGATTGTTTAAAGTTTGATTGCAGACACTGTAGAACATAACTCATTATGTTTCAGATAAGGTAACTCCTAGA
 321 TATCAAACTAATTTGTTGGGGTAGAGATTTTACAAGTCATGCCATTAGAAGATTTTCTCTGATATTATATGTGCAGTTCA
 401 GTTACAAGATGAAATCATGTTTTTTTAACAAAAGAGATAAAATACAATTGAAGCAAAAAATAACAGCTAGTATATAATAT
 481 ATACAGTCTGTATTTGCTTTTCACAGTAGGCCTGATGACTAAAAGATATGCTTTATTACACGCTATTTTCACCTCTTGAA
 561 AGTCAAAGGTGATGATTAATTTCATTTAGCAGGGAAGTGGAATAATATCTTTTGAAATAACTAAGTCCACTAAATTATAC
 641 AGTATGCTATTCTGGTTCTAAGTACATATTAGTCCCTTGGCAAATCTGTTCTTTCAAAGCATACCTTCCCCAAATGAGCC
 721 TACCTACTTCTTAAAAAACATATAACACAATGTGGTAGTAGTAGGTGTAAGGAAGGTAAGTTTTTTCATAGTGGTATGCA
 801 AACATATCATTGAAATATTACATAGATATAAAGACTTAGGGAATAAAAATAGCAGCAACAAATACTTGATAGATTTATCC
 881 TACTTGGGAGAAATATTTTGTAGCAGAGTATTTAGTATACTTAGAAGTTGATTTAGCAATTAGGCTTTAATGACCTTACA
 961 AAGTGAACATAACTGAACACAAGTATTTTTTCAATGCAAGATGAGGATGAAAATTTTACATTTCAACCCATCTGGCTAAA
1041 GTTAAGACTTAGCAAAAATTAAAATGTTGCCTTTGTCCAAGTATAGATTAAGGCAACAAACATATTTGGGTGTGTAATTT
1121 GAAGTTTTGGACTGAAATATCTTTGCAAGTATCCACATAAAATTCTGTAATGCCTTATAATTATATTCTAATAATTATGC
1201 ATTATACTAAGACACCATTAAGAACAGTTGAGGCACTACACTAAATCAAACCATAAATGAGGAAAAAACTTTTAATGTTC
1281 TTTTCTAGAAGTGTTCAAATAGGTCTTGATATGAAGCTAAAAGCCTTATTTATATTATCTTAATATTTCGGCTAAAATGT
1361 TAAGCTCCATAACATGAATTGATACAATTCCAATTTTATCAATATTTTGTGATAGAAAAATGTTAATATTATTCATGAGC
1441 TATACAGTCCTTACATTTTTTCCCTTGGTGTAGGAACAACGGAGGAGTTTCTCCTCTGCTAACTATTCATATATGTAACT
1521 GTAACAAAAGTGTACTATGTTATGCACACATTACAAATAATATAAGGGGAAGTTTTATTAGCTTAGTAGGAAATTGTTAT
1601 TATTAAGGTTTAAAAATGAGAACAGGTGTGAGTTTTCCAAAATACTTAAAAATAATAGTGTCAAAAATTCAGGGGCAGTT
1681 AAGGAGTCATGGATGGAACTAGAGGTCACTATATTAAGTGACATAAGCCAGAAACAGACAAACATTGCATGTTCTCAATT
1761 ATTTGCGGGATCTAAAAGTCAAAACAATTGAACTCATGGATATAGAGAGTAGAAGGATGGTTACTAGTGGCTGGGAAAAG
1841 GGGTGTGCGAGGGGAACTGGGGATGCTTAATGTGTACAAAAACTATGTAGTTAGAAAGTATAAATAAGACCTAGTATTTG
1921 ATAGCACAACCGGGTGAGTATAGTCAATAATAGCTTAATTGTACAAATAACTAAGAGTATAATTGGATTGTTTGTAACAC
2001 AAATAAATACTTGAGTGGATGGATACCCAATTA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ccUGUAACAA-AGUCACGGGUUCa 5'
            | | ||||  |  ||:||||| 
Target 5' ttAAAATGTTGCCTTTGTCCAAGt 3'
 1059 - 1082 141.00 -13.40
2 
miRNA  3' ccUGUAACAAAGUCACGGGUUCa 5'
            ||  || | |  | |||||| 
Target 5' gaACCATGCTGC--TACCCAAGa 3'
 109 - 129 121.00 -9.20
3 
miRNA  3' ccUGUAACAAAG-----UCACGGGUUca 5'
            |::|| |||:     ||||::|||  
Target 5' taATGTTCTTTTCTAGAAGTGTTCAAat 3'
 1273 - 1300 117.00 -7.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
368781 42 ClinVar
368780 44 ClinVar
368779 45 ClinVar
368778 132 ClinVar
368777 268 ClinVar
368776 312 ClinVar
913266 313 ClinVar
368775 352 ClinVar
368774 368 ClinVar
913265 484 ClinVar
368773 584 ClinVar
368772 635 ClinVar
368771 669 ClinVar
913264 686 ClinVar
368770 755 ClinVar
368769 775 ClinVar
912885 780 ClinVar
368768 835 ClinVar
912884 837 ClinVar
368767 1019 ClinVar
368766 1112 ClinVar
912883 1113 ClinVar
368765 1173 ClinVar
368764 1380 ClinVar
368763 1431 ClinVar
368762 1626 ClinVar
368761 1686 ClinVar
914837 1744 ClinVar
368760 1808 ClinVar
368759 1849 ClinVar
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs766542303 4 dbSNP
rs377237007 13 dbSNP
rs1372848256 14 dbSNP
rs772899957 17 dbSNP
rs1216458341 20 dbSNP
rs767407495 32 dbSNP
rs1269869618 33 dbSNP
rs761595726 34 dbSNP
rs768556295 35 dbSNP
rs748816246 37 dbSNP
rs1423942210 38 dbSNP
rs748327638 39 dbSNP
rs769331961 40 dbSNP
rs372539151 42 dbSNP
rs758862317 43 dbSNP
rs2227090 44 dbSNP
rs776879430 44 dbSNP
rs112147894 45 dbSNP
rs1491243449 46 dbSNP
rs747104592 46 dbSNP
rs762909156 46 dbSNP
rs768784756 46 dbSNP
rs1429374586 47 dbSNP
rs779587305 51 dbSNP
rs1248672188 56 dbSNP
rs1441669406 56 dbSNP
rs1020031451 58 dbSNP
rs1184969476 62 dbSNP
rs1380977264 69 dbSNP
rs1183577112 76 dbSNP
rs1434111313 93 dbSNP
rs916981607 97 dbSNP
rs908553818 116 dbSNP
rs1469692954 118 dbSNP
rs60804946 126 dbSNP
rs1057516021 132 dbSNP
rs1443322589 143 dbSNP
rs992649943 154 dbSNP
rs982743258 174 dbSNP
rs1458416008 186 dbSNP
rs186686442 193 dbSNP
rs1008263192 231 dbSNP
rs754705765 239 dbSNP
rs958525461 241 dbSNP
rs1035488951 243 dbSNP
rs1002272242 246 dbSNP
rs1211200264 247 dbSNP
rs1222802827 250 dbSNP
rs1268737277 263 dbSNP
rs12007581 268 dbSNP
rs1213809271 286 dbSNP
rs1260236193 289 dbSNP
rs1488893303 300 dbSNP
rs12008480 312 dbSNP
rs201276514 313 dbSNP
rs1480335165 328 dbSNP
rs984005565 329 dbSNP
rs759708330 335 dbSNP
rs751560456 352 dbSNP
rs998897159 361 dbSNP
rs6617041 368 dbSNP
rs1344121011 373 dbSNP
rs773834493 377 dbSNP
rs182040115 383 dbSNP
rs190271258 399 dbSNP
rs751221842 400 dbSNP
rs374960930 402 dbSNP
rs1288900514 410 dbSNP
rs1352197406 414 dbSNP
rs1222014142 427 dbSNP
rs1325610754 435 dbSNP
rs1316564676 437 dbSNP
rs993489153 462 dbSNP
rs899698578 466 dbSNP
rs1421740632 467 dbSNP
rs897927601 472 dbSNP
rs1254423238 474 dbSNP
rs1162946167 482 dbSNP
rs1469017302 484 dbSNP
rs1177156804 486 dbSNP
rs1038177026 496 dbSNP
rs941262404 501 dbSNP
rs1423316605 539 dbSNP
rs1406583194 541 dbSNP
rs908438371 542 dbSNP
rs1165082281 543 dbSNP
rs1009102534 546 dbSNP
rs1383061927 553 dbSNP
rs184716220 569 dbSNP
rs1372216247 571 dbSNP
rs1182915822 577 dbSNP
rs1057516020 584 dbSNP
rs1475319001 585 dbSNP
rs59823024 621 dbSNP
rs1230152065 627 dbSNP
rs764766864 635 dbSNP
rs936266124 637 dbSNP
rs898985022 644 dbSNP
rs761406985 655 dbSNP
rs904752597 660 dbSNP
rs1277150869 663 dbSNP
rs1436482162 664 dbSNP
rs41300878 669 dbSNP
rs191117227 686 dbSNP
rs1041800518 700 dbSNP
rs746571809 701 dbSNP
rs1022420486 707 dbSNP
rs1184845619 708 dbSNP
rs989583075 738 dbSNP
rs1319892471 739 dbSNP
rs41310691 755 dbSNP
rs1443593128 757 dbSNP
rs147030302 775 dbSNP
rs1421347517 776 dbSNP
rs772532129 780 dbSNP
rs377339269 784 dbSNP
rs917030933 786 dbSNP
rs1454516983 798 dbSNP
rs1334739081 803 dbSNP
rs373370381 810 dbSNP
rs1341307309 819 dbSNP
rs1436058490 831 dbSNP
rs997009153 833 dbSNP
rs1057516019 835 dbSNP
rs1337851606 856 dbSNP
rs899545941 859 dbSNP
rs756451310 863 dbSNP
rs983940886 865 dbSNP
rs1260653341 871 dbSNP
rs763465869 874 dbSNP
rs752981974 886 dbSNP
rs1188794903 896 dbSNP
rs1351663961 906 dbSNP
rs374007516 915 dbSNP
rs1474227753 928 dbSNP
rs1185648678 945 dbSNP
rs941146466 956 dbSNP
rs1425647239 961 dbSNP
rs1470886614 973 dbSNP
rs781516092 979 dbSNP
rs952756874 990 dbSNP
rs1457900127 992 dbSNP
rs755148457 1005 dbSNP
rs1320519763 1007 dbSNP
rs12557804 1019 dbSNP
rs1275775388 1031 dbSNP
rs1047050128 1035 dbSNP
rs939273672 1052 dbSNP
rs1222201225 1067 dbSNP
rs1263131790 1070 dbSNP
rs1322196499 1084 dbSNP
rs1173196311 1085 dbSNP
rs927960614 1101 dbSNP
rs1057516018 1112 dbSNP
rs980755922 1114 dbSNP
rs1263410631 1129 dbSNP
rs766504730 1130 dbSNP
rs200253251 1149 dbSNP
rs1444883005 1153 dbSNP
rs1214660081 1157 dbSNP
rs1247043198 1171 dbSNP
rs7062790 1173 dbSNP
rs867589008 1195 dbSNP
rs750350207 1196 dbSNP
rs1197186724 1200 dbSNP
rs1428586138 1205 dbSNP
rs1487248609 1213 dbSNP
rs764968147 1217 dbSNP
rs1247937268 1242 dbSNP
rs915296941 1251 dbSNP
rs1222303298 1252 dbSNP
rs1306781548 1269 dbSNP
rs1255945100 1273 dbSNP
rs1487982951 1288 dbSNP
rs1324515573 1292 dbSNP
rs761719185 1300 dbSNP
rs1220195375 1312 dbSNP
rs1367817858 1315 dbSNP
rs894258431 1317 dbSNP
rs1403546161 1327 dbSNP
rs781375602 1330 dbSNP
rs1282935402 1347 dbSNP
rs1217672828 1349 dbSNP
rs1369900558 1350 dbSNP
rs1008985932 1367 dbSNP
rs956892399 1378 dbSNP
rs188108033 1380 dbSNP
rs1290233947 1391 dbSNP
rs1490776205 1402 dbSNP
rs988163043 1408 dbSNP
rs183773653 1410 dbSNP
rs1483321195 1412 dbSNP
rs1029186670 1413 dbSNP
rs16980189 1431 dbSNP
rs758302493 1442 dbSNP
rs1000352616 1443 dbSNP
rs1466508725 1444 dbSNP
rs1429004464 1452 dbSNP
rs1175340221 1463 dbSNP
rs1422975657 1469 dbSNP
rs904804028 1470 dbSNP
rs1029746967 1474 dbSNP
rs1431092791 1480 dbSNP
rs996503304 1481 dbSNP
rs192625051 1495 dbSNP
rs1191212471 1503 dbSNP
rs899598547 1504 dbSNP
rs1333470788 1508 dbSNP
rs1016724210 1514 dbSNP
rs1361070524 1515 dbSNP
rs895489434 1518 dbSNP
rs1290702806 1530 dbSNP
rs1339893860 1530 dbSNP
rs1197455621 1531 dbSNP
rs1005300514 1546 dbSNP
rs886972603 1549 dbSNP
rs774994912 1550 dbSNP
rs1245071788 1558 dbSNP
rs1442951792 1561 dbSNP
rs1200429724 1566 dbSNP
rs1046858076 1572 dbSNP
rs1458090549 1573 dbSNP
rs1262271862 1579 dbSNP
rs771504333 1581 dbSNP
rs1396334170 1588 dbSNP
rs1397126955 1606 dbSNP
rs906425778 1607 dbSNP
rs1384395036 1618 dbSNP
rs16980188 1626 dbSNP
rs778301679 1632 dbSNP
rs1326803820 1639 dbSNP
rs778301082 1656 dbSNP
rs1229258856 1661 dbSNP
rs937104501 1664 dbSNP
rs927022492 1675 dbSNP
rs1223258946 1683 dbSNP
rs1057516017 1686 dbSNP
rs1374728938 1690 dbSNP
rs770167885 1697 dbSNP
rs748611522 1699 dbSNP
rs1204243201 1712 dbSNP
rs1265056534 1715 dbSNP
rs1048725314 1720 dbSNP
rs188411180 1721 dbSNP
rs1183217398 1723 dbSNP
rs1248942193 1727 dbSNP
rs1448155281 1737 dbSNP
rs1430537326 1738 dbSNP
rs573056182 1747 dbSNP
rs915223552 1749 dbSNP
rs1191401540 1751 dbSNP
rs755239581 1766 dbSNP
rs1466960953 1767 dbSNP
rs935410590 1768 dbSNP
rs1407621889 1774 dbSNP
rs1301393755 1776 dbSNP
rs924120533 1777 dbSNP
rs1464243305 1780 dbSNP
rs987619181 1785 dbSNP
rs972672257 1789 dbSNP
rs1362133534 1793 dbSNP
rs965247719 1805 dbSNP
rs56307558 1808 dbSNP
rs922180887 1814 dbSNP
rs1180502401 1818 dbSNP
rs1440160610 1821 dbSNP
rs975389340 1834 dbSNP
rs1283807551 1836 dbSNP
rs1041966980 1844 dbSNP
rs193178388 1848 dbSNP
rs73513629 1849 dbSNP
rs758507048 1851 dbSNP
rs1296833838 1862 dbSNP
rs1198461217 1867 dbSNP
rs1261392455 1869 dbSNP
rs953468478 1871 dbSNP
rs1203636385 1888 dbSNP
rs1484380193 1890 dbSNP
rs1029068098 1899 dbSNP
rs1202227222 1900 dbSNP
rs1427891118 1905 dbSNP
rs1215306551 1908 dbSNP
rs1480397155 1908 dbSNP
rs1175031337 1922 dbSNP
rs1351677586 1934 dbSNP
rs1000808586 1935 dbSNP
rs763807528 1936 dbSNP
rs1005311839 1937 dbSNP
rs951069832 1940 dbSNP
rs1383964574 1956 dbSNP
rs968911727 1968 dbSNP
rs1304742628 1983 dbSNP
rs750513697 1983 dbSNP
rs1025915746 1991 dbSNP
rs765261633 1995 dbSNP
rs1288248888 1996 dbSNP
rs1241515670 2004 dbSNP
rs1020832287 2005 dbSNP
rs1010496803 2008 dbSNP
rs896043399 2009 dbSNP
rs1003348232 2013 dbSNP
rs1311059187 2016 dbSNP
rs906344526 2017 dbSNP
rs1398197791 2021 dbSNP
rs1380321451 2023 dbSNP
rs1303125311 2025 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 79983.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000262753.4 | 3UTR | GAAAUCUAAUGGAAUGAAUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla 0.741 1.9e-3 0.736 2.1e-3 13 Click to see details
GSE28544 Breast cancer 0.567 1.9e-3 0.434 1.7e-2 24 Click to see details
GSE17498 Multiple myeloma -0.241 6.7e-2 -0.194 1.2e-1 40 Click to see details
GSE27834 Pluripotent stem cells -0.252 1.7e-1 -0.350 9.2e-2 16 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.221 1.7e-1 -0.283 1.1e-1 20 Click to see details
GSE38226 Liver fibrosis -0.205 1.9e-1 -0.165 2.4e-1 21 Click to see details
GSE21849 B cell lymphoma -0.137 2.4e-1 -0.144 2.3e-1 29 Click to see details
GSE32688 Pancreatic cancer 0.083 3.3e-1 -0.026 4.4e-1 32 Click to see details
GSE17306 Multiple myeloma 0.049 3.7e-1 0.483 2.2e-4 49 Click to see details
GSE21687 Ependynoma primary tumors -0.038 3.8e-1 -0.054 3.4e-1 64 Click to see details
GSE26953 Aortic valvular endothelial cells -0.063 3.8e-1 -0.068 3.8e-1 24 Click to see details
GSE14794 Lymphoblastoid cells 0.027 4.0e-1 0.074 2.4e-1 90 Click to see details
GSE42095 Differentiated embryonic stem cells 0.047 4.2e-1 -0.026 4.5e-1 23 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.015 4.7e-1 -0.078 3.6e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.015 4.7e-1 -0.078 3.6e-1 25 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.015 4.7e-1 -0.078 3.6e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
48 hsa-miR-635 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055249 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT150167 MIDN midnolin 2 2
MIRT198486 USP14 ubiquitin specific peptidase 14 2 6
MIRT446204 GTPBP4 GTP binding protein 4 2 2
MIRT453083 SUMF2 sulfatase modifying factor 2 2 6
MIRT462505 MTFMT mitochondrial methionyl-tRNA formyltransferase 2 8
MIRT474413 KLHL28 kelch like family member 28 2 8
MIRT479376 CELF1 CUGBP Elav-like family member 1 2 4
MIRT498090 SEMA7A semaphorin 7A (John Milton Hagen blood group) 2 2
MIRT525565 MTRNR2L7 MT-RNR2-like 7 2 6
MIRT525613 MTRNR2L3 MT-RNR2-like 3 2 4
MIRT531868 POF1B premature ovarian failure, 1B 2 2
MIRT535789 MTRNR2L11 MT-RNR2-like 11 2 6
MIRT535807 MTRNR2L10 MT-RNR2-like 10 2 4
MIRT539940 IFNAR2 interferon alpha and beta receptor subunit 2 2 2
MIRT563194 C15orf38-AP3S2 C15orf38-AP3S2 readthrough 2 2
MIRT563803 AP3S2 adaptor related protein complex 3 sigma 2 subunit 2 2
MIRT576360 Pxdn peroxidasin 2 2
MIRT615575 NCS1 neuronal calcium sensor 1 2 2
MIRT620858 SERPING1 serpin family G member 1 2 2
MIRT623189 NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2 2
MIRT625116 SLC1A5 solute carrier family 1 member 5 2 2
MIRT625128 NUP93 nucleoporin 93 2 2
MIRT625904 LINC00632 long intergenic non-protein coding RNA 632 2 2
MIRT626820 PRR11 proline rich 11 2 2
MIRT628142 HM13 histocompatibility minor 13 2 2
MIRT633789 ZNF490 zinc finger protein 490 2 2
MIRT634385 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT636563 EPB41 erythrocyte membrane protein band 4.1 2 2
MIRT643446 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT646006 HTRA1 HtrA serine peptidase 1 2 2
MIRT652141 TRPM7 transient receptor potential cation channel subfamily M member 7 2 2
MIRT652672 TIMELESS timeless circadian clock 2 2
MIRT658341 FAM83D family with sequence similarity 83 member D 2 2
MIRT658890 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT659518 CHST3 carbohydrate sulfotransferase 3 2 2
MIRT668590 ELAVL3 ELAV like RNA binding protein 3 2 2
MIRT670258 ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2 2
MIRT686721 TBC1D13 TBC1 domain family member 13 2 2
MIRT701899 MNT MAX network transcriptional repressor 2 2
MIRT702764 IGF1R insulin like growth factor 1 receptor 2 2
MIRT705290 B4GALT1 beta-1,4-galactosyltransferase 1 2 2
MIRT710836 BASP1 brain abundant membrane attached signal protein 1 2 2
MIRT711732 NUPL2 nucleoporin like 2 2 2
MIRT717619 SLC30A10 solute carrier family 30 member 10 2 2
MIRT719453 APBA1 amyloid beta precursor protein binding family A member 1 2 2
MIRT720819 CIAO1 cytosolic iron-sulfur assembly component 1 2 2
MIRT723454 CUL4A cullin 4A 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-635 Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-635 Cisplatin 5460033 NSC119875 approved resistant cell line
hsa-miR-635 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-635 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-635 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM47)
hsa-miR-635 Paclitaxel 36314 NSC125973 approved resistant cell line (PC3PR200)
hsa-miR-635 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-635 Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)

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