miRTarBase - #MIRT532230


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pre-miRNA Information
pre-miRNA hsa-mir-6715b   
Genomic Coordinates chr10: 112299612 - 112299688
Description Homo sapiens miR-6715b stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6715b-3p
Sequence 46| CUCAAACCGGCUGUGCCUGUGG |67
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs761643095 7 dbSNP
rs768295556 8 dbSNP
rs182337914 9 dbSNP
rs1369684979 11 dbSNP
rs776704371 13 dbSNP
rs1039819520 15 dbSNP
rs771110697 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol KLF2   
Synonyms LKLF
Description Kruppel like factor 2
Transcript NM_016270   
Expression
Putative miRNA Targets on KLF2
3'UTR of KLF2
(miRNA target sites are highlighted)		 
>KLF2|NM_016270|3'UTR
   1 CCGGGACGCCCCCGCCCACCTGCGCGCGGCCGTGGCGGGTCCCACGCGCCGGGCGCGGCCCCCTCCCAAACTGTGACTGG
  81 TATTTATTGGACCCAGAGAACCGGGCCGGGCACAGCGTGGCTACAGAGGGTCTCCCTCGATGACGACGACGACGACGCCA
 161 CCACCCCAGCCCCCGTCTGTGACTGAAGGCCCGGTGGGAAAAGACCACGATCCTCCTTGACGAGTTTTGTTTTTCAAAAT
 241 GGTGCAATAATTTAAGTGGCATCTTCTCTCCCACCGGGTCTACACTAGAGGATCGAGGCTTGTGATGCCTTGTGAGAAAT
 321 AAGGGCCTTAATTTGTACTGTCTGCGGCATTTTTTATAATATTGTATATAGTGACTGACAAATATTGTATTACTGTACAT
 401 AGAGAGACAGGTGGGCATTTTTGGGCTACCTGGTTCGTTTTTATAAGATTTTGCTGGGTTGGTTTTTTTTTTAATTAAAA
 481 AGTTTTGCATCTTTTAAAAAAAATCACAGCACTGGTCTGGTTGCTTGGAACTGGGGCCTTGGGGCACTTGGGAGGAGGGG
 561 GGAGCGGAGAGTTTGATGGAGGGCAGCCCCACTAAAGCATCGTGTGCAGTGGGTCCTGCGTCTGCCAGCACCGGGACTGC
 641 CAGCTGCTGTGCCTGCCTGCCAGGAACCTGTGGGTTTTTCTGTAAATTTAGACACTGCATTTTAGGACTGAGGGAGGGTT
 721 ATTTTAAGGTTGTTCTTTGAGCCATAAATTGCCTCTTTGCCCCACAGCTGGGGAAAGTGCTGGTCCCACTGACGTGGCCT
 801 CCTCTACGTTGAAAAAAATAAAACTACTTACCTCTTCCTGGAAGCCTCTGAGGTTTTAGCCAAATTTCTGGAGTGCCAGC
 881 TCTATATTTTTATTTTTATTTTTAAAGGGGGTTAACCTGCTGAGTTTCTGGCATGTTCTGCCCTTTACTCGTCTCGACAT
 961 TTAGCAAGTCTTTTCTTAAGGGGTGAGTTCCCCATTCTGCTAGCGGAAAACAGTGAAACCTGCATTCGAGGGCCATGCAT
1041 GAAGCTCTTTTCCAGATGAGGAAACGGAGGCCCGGAGAGGTAGCGGCAGGGTGGTGGAGTTGGGTTGTTAGCCTGCTCTG
1121 TCTGCCTCCAAGGGTCCCTGAACCCCACTGGAAGGGAGTGGTAGCTTTCTACAATGACCCACCTGTTGTGTGCATTGGAA
1201 GGCTAGGAGAGCCTCCTCCCCTGTAGGTCTCCTGGTGCAAAAAATTCACTGCCTCAATGGTAGGAGGTGACCAGTCTGGA
1281 AACCCACCTGGAGAGCAGAGGAGACCCCTAAATCCCACCACCCCAAGTGTCTCAGGCAAGGAGGTATCTCTCCCCCCAGA
1361 TTTCACCTGCCACCCCTCACCTTCCCCATTCTCAGGGGCCCCGGGTAACCATGACCACCAACCATTGCACAAGTTTCCAG
1441 AAAGTGAAAATAGCTCGTAAGCAGCGCCTGCTTTAAAACACTCTCACCCCGTTGCGACAGAGGCTGGGATTTCCTCCCTC
1521 CCTGCATCCTTCCTCCTCCCCAACTACGGCAGCCCTGGAAACAGCTGAGAGGTGTTTGGTAATCCACGAAAAGCAGAAAT
1601 ACGATTTGACAATCTGATTCATTTTCCGAGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ggUGUCCGUGUCGGCCAAACUc 5'
            :|||  |:|  || ||||| 
Target 5' aaGCAGAAATA--CGATTTGAc 3'
 1591 - 1610 124.00 -7.00
2 
miRNA  3' ggugUCCGUGUCGGCCAAACUc 5'
              :|| :|:|   |||||| 
Target 5' agggGGGAGCGGAGAGTTTGAt 3'
 556 - 577 122.00 -12.20
3 
miRNA  3' gguGUCCGU-GUCGGCCAAAcuc 5'
             |||| | | |: |||||   
Target 5' tgcCAGGAACCTGTGGGTTTttc 3'
 658 - 680 119.00 -11.62
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1182815 172 ClinVar
COSM8438365 1 COSMIC
COSN30175594 41 COSMIC
COSN1211653 56 COSMIC
COSN17497132 65 COSMIC
COSN30537054 67 COSMIC
COSN17441175 132 COSMIC
COSN31569381 145 COSMIC
COSN20115499 222 COSMIC
COSN23053042 293 COSMIC
COSN20934654 427 COSMIC
COSN4777263 710 COSMIC
COSN27928066 819 COSMIC
COSN27261649 820 COSMIC
COSN29614069 824 COSMIC
rs8810 474 GWAS
rs11086029 820 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1464025511 2 dbSNP
rs368246111 3 dbSNP
rs759105086 4 dbSNP
rs1465123904 5 dbSNP
rs752216225 8 dbSNP
rs1005834549 9 dbSNP
rs963072744 9 dbSNP
rs1425441833 13 dbSNP
rs758329389 15 dbSNP
rs1023416103 16 dbSNP
rs969115032 20 dbSNP
rs1322720764 21 dbSNP
rs1389567966 23 dbSNP
rs777798909 24 dbSNP
rs1452204887 25 dbSNP
rs751407765 26 dbSNP
rs757079949 28 dbSNP
rs781589332 32 dbSNP
rs1306887842 33 dbSNP
rs998753140 38 dbSNP
rs1226039825 39 dbSNP
rs1269486507 40 dbSNP
rs1036792926 41 dbSNP
rs1465025478 41 dbSNP
rs896997780 45 dbSNP
rs1209022966 48 dbSNP
rs1230111578 49 dbSNP
rs770027435 51 dbSNP
rs1484097480 52 dbSNP
rs928796235 54 dbSNP
rs938935734 55 dbSNP
rs1167305339 56 dbSNP
rs2293811 57 dbSNP
rs532846059 60 dbSNP
rs1161512818 61 dbSNP
rs989043171 63 dbSNP
rs950116716 65 dbSNP
rs540224684 71 dbSNP
rs1463335003 72 dbSNP
rs947413525 74 dbSNP
rs1213971213 87 dbSNP
rs1032943962 93 dbSNP
rs1287196426 104 dbSNP
rs560236310 105 dbSNP
rs1271795587 107 dbSNP
rs1298910260 108 dbSNP
rs758912598 113 dbSNP
rs1363421924 121 dbSNP
rs1328308781 130 dbSNP
rs1437519761 131 dbSNP
rs199758859 138 dbSNP
rs1447544332 142 dbSNP
rs769364180 142 dbSNP
rs927082569 142 dbSNP
rs528887573 145 dbSNP
rs1191537989 148 dbSNP
rs531785266 151 dbSNP
rs1048830997 153 dbSNP
rs181837356 156 dbSNP
rs1184403377 158 dbSNP
rs1483068295 159 dbSNP
rs1276012099 161 dbSNP
rs1228365905 163 dbSNP
rs890260067 165 dbSNP
rs1306164932 166 dbSNP
rs15336 172 dbSNP
rs1367181178 175 dbSNP
rs760359676 176 dbSNP
rs1444490605 177 dbSNP
rs1164002675 180 dbSNP
rs998364633 184 dbSNP
rs1415436620 189 dbSNP
rs1051674099 193 dbSNP
rs899066546 205 dbSNP
rs1402324077 208 dbSNP
rs763086845 210 dbSNP
rs1159759215 218 dbSNP
rs1344612408 220 dbSNP
rs34871366 221 dbSNP
rs1422646576 222 dbSNP
rs397897528 222 dbSNP
rs994536349 226 dbSNP
rs1023278856 228 dbSNP
rs1472697311 229 dbSNP
rs1250496329 241 dbSNP
rs1304792682 248 dbSNP
rs1356388178 249 dbSNP
rs1204666819 251 dbSNP
rs11549469 252 dbSNP
rs1414513603 256 dbSNP
rs1291771969 258 dbSNP
rs1202391350 260 dbSNP
rs1331680003 261 dbSNP
rs1224764949 262 dbSNP
rs531552351 264 dbSNP
rs1258220197 267 dbSNP
rs1211287147 276 dbSNP
rs1284263091 277 dbSNP
rs1311929161 277 dbSNP
rs1315801911 279 dbSNP
rs1230514221 283 dbSNP
rs969564064 288 dbSNP
rs1213096082 311 dbSNP
rs1259142892 321 dbSNP
rs1351323700 334 dbSNP
rs1033055672 336 dbSNP
rs768860517 340 dbSNP
rs1186809304 342 dbSNP
rs1303308659 350 dbSNP
rs551245540 352 dbSNP
rs1465384630 357 dbSNP
rs1036277343 366 dbSNP
rs1160993711 370 dbSNP
rs1457498540 372 dbSNP
rs1255066277 375 dbSNP
rs960269196 380 dbSNP
rs1471041863 386 dbSNP
rs957404650 400 dbSNP
rs1475870656 401 dbSNP
rs753656774 401 dbSNP
rs1182913301 405 dbSNP
rs1398998328 405 dbSNP
rs989383289 407 dbSNP
rs1254682937 409 dbSNP
rs185032045 416 dbSNP
rs947610103 423 dbSNP
rs981312356 434 dbSNP
rs927149421 437 dbSNP
rs1226673479 438 dbSNP
rs1434283165 445 dbSNP
rs1323539375 446 dbSNP
rs958546382 448 dbSNP
rs1376869306 463 dbSNP
rs984577306 463 dbSNP
rs75043886 464 dbSNP
rs908953232 469 dbSNP
rs1156444897 471 dbSNP
rs1443459562 471 dbSNP
rs940345883 472 dbSNP
rs551294160 473 dbSNP
rs8810 474 dbSNP
rs1221464237 475 dbSNP
rs1281782739 478 dbSNP
rs1254604718 479 dbSNP
rs1190920927 480 dbSNP
rs934206364 484 dbSNP
rs761926127 488 dbSNP
rs1051338731 490 dbSNP
rs889992881 491 dbSNP
rs1007007072 496 dbSNP
rs1209625856 496 dbSNP
rs539702388 496 dbSNP
rs978749060 497 dbSNP
rs1439326062 505 dbSNP
rs1182315664 511 dbSNP
rs7247605 518 dbSNP
rs1318265228 531 dbSNP
rs1468497001 532 dbSNP
rs1195442339 535 dbSNP
rs1395701101 550 dbSNP
rs1388204949 557 dbSNP
rs1020676644 559 dbSNP
rs1292434551 560 dbSNP
rs932065276 562 dbSNP
rs45572134 565 dbSNP
rs12975711 566 dbSNP
rs1187053234 567 dbSNP
rs556458410 569 dbSNP
rs1328556198 581 dbSNP
rs1353145019 582 dbSNP
rs35663614 587 dbSNP
rs397714015 587 dbSNP
rs397743462 587 dbSNP
rs1304814861 589 dbSNP
rs1051887618 598 dbSNP
rs1295209637 608 dbSNP
rs1371086200 620 dbSNP
rs911958955 621 dbSNP
rs1300775340 628 dbSNP
rs958561738 633 dbSNP
rs189020404 635 dbSNP
rs1196046606 638 dbSNP
rs940560941 641 dbSNP
rs1308088481 642 dbSNP
rs984588587 646 dbSNP
rs1370482050 665 dbSNP
rs1166522225 675 dbSNP
rs1271958738 686 dbSNP
rs1435874716 689 dbSNP
rs1036186702 694 dbSNP
rs1253612427 696 dbSNP
rs899096158 705 dbSNP
rs1191874152 716 dbSNP
rs772854594 717 dbSNP
rs1475836664 718 dbSNP
rs1482688726 721 dbSNP
rs1167570610 723 dbSNP
rs1201984092 729 dbSNP
rs1417731136 730 dbSNP
rs1345400859 740 dbSNP
rs1044756127 743 dbSNP
rs1230667298 744 dbSNP
rs1351935136 747 dbSNP
rs1288505049 753 dbSNP
rs961767197 758 dbSNP
rs545595614 761 dbSNP
rs971736489 762 dbSNP
rs145552369 768 dbSNP
rs904823145 772 dbSNP
rs1394457157 774 dbSNP
rs1416551505 774 dbSNP
rs1403408304 777 dbSNP
rs1439475094 783 dbSNP
rs1331548083 785 dbSNP
rs1468491552 785 dbSNP
rs572598627 794 dbSNP
rs922957281 800 dbSNP
rs932981844 801 dbSNP
rs1249564142 802 dbSNP
rs1189585041 809 dbSNP
rs1255283532 812 dbSNP
rs200401747 812 dbSNP
rs201316783 819 dbSNP
rs539996009 819 dbSNP
rs11086029 820 dbSNP
rs1269302501 822 dbSNP
rs1315826971 823 dbSNP
rs1234962071 828 dbSNP
rs1273707403 831 dbSNP
rs1003613451 832 dbSNP
rs528924924 838 dbSNP
rs956645764 840 dbSNP
rs893237950 841 dbSNP
rs1334002923 842 dbSNP
rs1211767846 844 dbSNP
rs1450830270 845 dbSNP
rs45492593 851 dbSNP
rs1447661883 853 dbSNP
rs112320919 858 dbSNP
rs1160125150 858 dbSNP
rs181740267 864 dbSNP
rs1020384788 877 dbSNP
rs968943669 878 dbSNP
rs1367753656 883 dbSNP
rs1181539219 885 dbSNP
rs149936786 885 dbSNP
rs531458367 885 dbSNP
rs978947898 894 dbSNP
rs1476377015 896 dbSNP
rs1166151319 898 dbSNP
rs1417630137 908 dbSNP
rs1291480393 912 dbSNP
rs551648617 935 dbSNP
rs1034686559 943 dbSNP
rs1460290112 944 dbSNP
rs1160809221 951 dbSNP
rs564972216 952 dbSNP
rs1386492981 954 dbSNP
rs766257145 957 dbSNP
rs753808712 963 dbSNP
rs1317170179 964 dbSNP
rs922168904 968 dbSNP
rs1434717073 977 dbSNP
rs1343648453 978 dbSNP
rs1325614281 984 dbSNP
rs953442076 990 dbSNP
rs1405969183 993 dbSNP
rs35995026 995 dbSNP
rs1161555127 999 dbSNP
rs1006077003 1005 dbSNP
rs527464231 1006 dbSNP
rs547600023 1008 dbSNP
rs1474262470 1010 dbSNP
rs1248031376 1020 dbSNP
rs912011326 1022 dbSNP
rs961858997 1025 dbSNP
rs1450493947 1028 dbSNP
rs185691356 1029 dbSNP
rs1220961106 1039 dbSNP
rs1293631190 1045 dbSNP
rs1030075249 1046 dbSNP
rs1298886917 1051 dbSNP
rs954536020 1056 dbSNP
rs940744751 1058 dbSNP
rs1333905141 1059 dbSNP
rs45539835 1061 dbSNP
rs549726680 1066 dbSNP
rs754422931 1075 dbSNP
rs920388863 1085 dbSNP
rs990350681 1091 dbSNP
rs893411862 1093 dbSNP
rs1371087295 1094 dbSNP
rs1351478113 1101 dbSNP
rs35878925 1102 dbSNP
rs914767484 1102 dbSNP
rs1282385083 1104 dbSNP
rs1002985008 1106 dbSNP
rs1477477563 1107 dbSNP
rs1188946828 1112 dbSNP
rs1257177997 1114 dbSNP
rs1484324870 1115 dbSNP
rs1042225888 1116 dbSNP
rs930555846 1116 dbSNP
rs1306088136 1119 dbSNP
rs1045037931 1123 dbSNP
rs1379222307 1128 dbSNP
rs907249431 1132 dbSNP
rs1367157766 1133 dbSNP
rs905107328 1138 dbSNP
rs764743508 1139 dbSNP
rs1056504387 1141 dbSNP
rs1364933732 1145 dbSNP
rs1439891243 1148 dbSNP
rs756326623 1151 dbSNP
rs570020251 1155 dbSNP
rs892232647 1166 dbSNP
rs1157443873 1170 dbSNP
rs894409848 1175 dbSNP
rs1006170437 1178 dbSNP
rs1160761005 1180 dbSNP
rs1472605134 1186 dbSNP
rs1009231765 1190 dbSNP
rs1177178142 1210 dbSNP
rs1479932317 1212 dbSNP
rs1239640957 1221 dbSNP
rs897700190 1222 dbSNP
rs76570748 1230 dbSNP
rs1230336361 1231 dbSNP
rs1329970780 1232 dbSNP
rs968889681 1235 dbSNP
rs1313117376 1238 dbSNP
rs1030498444 1239 dbSNP
rs1306353458 1239 dbSNP
rs559195119 1257 dbSNP
rs1381245629 1260 dbSNP
rs1303213583 1265 dbSNP
rs1446943123 1285 dbSNP
rs1000315963 1286 dbSNP
rs1403468955 1288 dbSNP
rs954463185 1297 dbSNP
rs1457406186 1304 dbSNP
rs1309030394 1315 dbSNP
rs1336316742 1316 dbSNP
rs1417856062 1317 dbSNP
rs757953141 1322 dbSNP
rs1007653679 1325 dbSNP
rs754790794 1325 dbSNP
rs957685007 1336 dbSNP
rs1210849841 1337 dbSNP
rs1283908513 1344 dbSNP
rs1260226312 1347 dbSNP
rs1465470452 1347 dbSNP
rs990403335 1349 dbSNP
rs1323491724 1351 dbSNP
rs953747103 1358 dbSNP
rs1279959535 1368 dbSNP
rs987503747 1371 dbSNP
rs1380347052 1377 dbSNP
rs1019342580 1378 dbSNP
rs967956860 1379 dbSNP
rs1251734791 1392 dbSNP
rs1458980218 1393 dbSNP
rs962125663 1395 dbSNP
rs972109593 1397 dbSNP
rs1352164891 1398 dbSNP
rs1166154201 1399 dbSNP
rs572587291 1403 dbSNP
rs1180305569 1404 dbSNP
rs191241742 1411 dbSNP
rs1261283059 1412 dbSNP
rs1377877947 1413 dbSNP
rs1489488275 1416 dbSNP
rs928727732 1419 dbSNP
rs867056537 1424 dbSNP
rs1173861628 1426 dbSNP
rs1374522657 1432 dbSNP
rs930503740 1433 dbSNP
rs553931914 1434 dbSNP
rs1325546664 1437 dbSNP
rs1464328838 1448 dbSNP
rs1292965020 1454 dbSNP
rs1299628649 1458 dbSNP
rs1396971899 1466 dbSNP
rs938750520 1467 dbSNP
rs1424593303 1469 dbSNP
rs546403766 1471 dbSNP
rs1170939868 1477 dbSNP
rs1430783001 1489 dbSNP
rs1373277932 1491 dbSNP
rs1056268815 1492 dbSNP
rs1235185997 1494 dbSNP
rs1435078344 1496 dbSNP
rs1268162553 1497 dbSNP
rs1198699067 1500 dbSNP
rs915936675 1504 dbSNP
rs942007058 1508 dbSNP
rs34336808 1516 dbSNP
rs1205665189 1518 dbSNP
rs1310626552 1521 dbSNP
rs1229920210 1525 dbSNP
rs926572520 1526 dbSNP
rs1249358123 1527 dbSNP
rs1252193715 1536 dbSNP
rs1037631399 1538 dbSNP
rs1480513797 1541 dbSNP
rs565465642 1546 dbSNP
rs4808046 1549 dbSNP
rs1344226492 1552 dbSNP
rs571403403 1554 dbSNP
rs993756591 1565 dbSNP
rs892091294 1571 dbSNP
rs1166456494 1572 dbSNP
rs1469399611 1586 dbSNP
rs147006111 1588 dbSNP
rs890275592 1589 dbSNP
rs1043492130 1591 dbSNP
rs1253936166 1603 dbSNP
rs1007336187 1604 dbSNP
rs1393987793 1612 dbSNP
rs45517532 1628 dbSNP
rs749605660 1629 dbSNP
rs1201961543 1631 dbSNP
rs1000346869 1640 dbSNP
rs1010494077 1641 dbSNP
rs1262101366 1642 dbSNP
rs565162479 1647 dbSNP
rs1330645528 1651 dbSNP
rs1288376259 1654 dbSNP
rs1240405239 1655 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 10365.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gguguccgugucGGCCAAACUc 5'
                      ::||||||| 
Target 5' guuuuauuuuguUUGGUUUGAg 3'
 		3 - 24
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000248071.5 | 3UTR | AGGUUUUAUUUUGUUUGGUUUGAGAUAGGGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
75 hsa-miR-6715b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT080245 SMAD4 SMAD family member 4 2 2
MIRT142553 TNRC6A trinucleotide repeat containing 6A 2 4
MIRT384667 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT446660 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT463754 YTHDC1 YTH domain containing 1 2 2
MIRT476873 FEM1B fem-1 homolog B 2 2
MIRT478429 DAZAP2 DAZ associated protein 2 2 2
MIRT495237 SPRY3 sprouty RTK signaling antagonist 3 2 4
MIRT495945 ANKRD52 ankyrin repeat domain 52 2 2
MIRT497116 TYW3 tRNA-yW synthesizing protein 3 homolog 2 2
MIRT497344 RPP25L ribonuclease P/MRP subunit p25 like 2 2
MIRT498133 KLHL3 kelch like family member 3 2 2
MIRT502306 GNA13 G protein subunit alpha 13 2 2
MIRT510854 RAN RAN, member RAS oncogene family 2 8
MIRT513323 KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 2 6
MIRT523995 DTX4 deltex E3 ubiquitin ligase 4 2 4
MIRT525837 FAR2 fatty acyl-CoA reductase 2 2 2
MIRT527506 MYD88 myeloid differentiation primary response 88 2 2
MIRT527668 CIT citron rho-interacting serine/threonine kinase 2 2
MIRT527996 NDNF neuron derived neurotrophic factor 2 2
MIRT528052 MRS2 MRS2, magnesium transporter 2 2
MIRT528257 GPRIN2 G protein regulated inducer of neurite outgrowth 2 2 2
MIRT529401 ICK intestinal cell kinase 2 2
MIRT529558 SNRNP48 small nuclear ribonucleoprotein U11/U12 subunit 48 2 2
MIRT530323 TNFRSF10D TNF receptor superfamily member 10d 2 2
MIRT532230 KLF2 Kruppel like factor 2 2 2
MIRT534220 SLC35G1 solute carrier family 35 member G1 2 2
MIRT536195 MAML2 mastermind like transcriptional coactivator 2 2 2
MIRT538093 DEPDC1 DEP domain containing 1 2 2
MIRT543159 GTF2A1 general transcription factor IIA subunit 1 2 2
MIRT545840 ZNF264 zinc finger protein 264 2 4
MIRT546401 SRP9 signal recognition particle 9 2 2
MIRT550643 SLC39A7 solute carrier family 39 member 7 2 2
MIRT558648 CNKSR3 CNKSR family member 3 2 2
MIRT562208 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT562886 NACA2 nascent polypeptide associated complex alpha subunit 2 2 2
MIRT566786 MKL2 MKL1/myocardin like 2 2 2
MIRT567508 FOXC1 forkhead box C1 2 2
MIRT570235 CPNE5 copine 5 2 2
MIRT576823 Tgfbr3 transforming growth factor, beta receptor III 2 2
MIRT610704 GPX6 glutathione peroxidase 6 2 2
MIRT611141 CRISP1 cysteine rich secretory protein 1 2 4
MIRT618100 PPP5D1 PPP5 tetratricopeptide repeat domain containing 1 2 2
MIRT619086 OMA1 OMA1 zinc metallopeptidase 2 2
MIRT619716 FCF1 FCF1, rRNA-processing protein 2 2
MIRT620953 POLR2D RNA polymerase II subunit D 2 2
MIRT624645 ASXL3 additional sex combs like 3, transcriptional regulator 2 2
MIRT624655 ARMC10 armadillo repeat containing 10 2 2
MIRT630778 KLHL42 kelch like family member 42 2 4
MIRT635596 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT637122 MKX mohawk homeobox 2 2
MIRT645527 ZWINT ZW10 interacting kinetochore protein 2 2
MIRT647249 PTGDR2 prostaglandin D2 receptor 2 2 2
MIRT651508 WNT9A Wnt family member 9A 2 2
MIRT658721 ELK4 ELK4, ETS transcription factor 2 2
MIRT658804 EFNA5 ephrin A5 2 2
MIRT659319 CSRNP3 cysteine and serine rich nuclear protein 3 2 2
MIRT664605 UGT3A1 UDP glycosyltransferase family 3 member A1 2 2
MIRT666047 STON2 stonin 2 2 2
MIRT672228 PDE7B phosphodiesterase 7B 2 2
MIRT683243 WFDC6 WAP four-disulfide core domain 6 2 2
MIRT686565 TPM3 tropomyosin 3 2 2
MIRT697560 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT699294 SLC5A3 solute carrier family 5 member 3 2 2
MIRT707134 TRA2B transformer 2 beta homolog 2 2
MIRT712255 PTPRN2 protein tyrosine phosphatase, receptor type N2 2 2
MIRT713896 IGF2R insulin like growth factor 2 receptor 2 2
MIRT716186 UBN2 ubinuclein 2 2 2
MIRT716525 KSR2 kinase suppressor of ras 2 2 2
MIRT716968 CNOT6 CCR4-NOT transcription complex subunit 6 2 2
MIRT717154 LRRC3C leucine rich repeat containing 3C 2 2
MIRT718669 LSM10 LSM10, U7 small nuclear RNA associated 2 2
MIRT722100 PTBP3 polypyrimidine tract binding protein 3 2 2
MIRT723569 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT724703 CRAMP1L cramped chromatin regulator homolog 1 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6715b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-6715b-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)

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