miRTarBase - #MIRT532433


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pre-miRNA Information
pre-miRNA hsa-mir-216b   
Genomic Coordinates chr2: 56000714 - 56000795
Description Homo sapiens miR-216b stem-loop
Comment This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques .
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-216b-3p
Sequence 49| ACACACUUACCCGUAGAGAUUCUA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 9 2 - 56000739 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1032185572 4 dbSNP
rs1291886633 6 dbSNP
rs1195180466 10 dbSNP
rs761473579 10 dbSNP
rs751204276 12 dbSNP
rs368125248 13 dbSNP
rs755646560 13 dbSNP
rs1307586870 14 dbSNP
rs907200088 16 dbSNP
rs763696104 22 dbSNP
rs762699560 24 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Biomarker Information
Biomarker ID Name Type Discovered From Mode Level Source Testing Methods
B5PHM2 miR-216b Safety Biomarker (SAF) Clinical/Experimental Data Expression Increase Plasma MiRNA qPCR analyses
Gene Information
Gene Symbol DHX33   
Synonyms DDX33
Description DEAH-box helicase 33
Transcript NM_020162   
Expression
Putative miRNA Targets on DHX33
3'UTR of DHX33
(miRNA target sites are highlighted)		 
>DHX33|NM_020162|3'UTR
   1 GCCGCCCCAGGATGCCGCCAGAATCACTGGTCCCTGGGAGCTTGGACTACAGTTGTCCTTACAGCAGGCTTCCAGGTTGG
  81 CGCTTAGAGAAGCCTTGGAATCAGCTGAAGGTGCCTGACTTCCAGGAGCGTGAAAGCATCTTTGCTCAACTCCTGGGACT
 161 GAACCATATAGACATGGACATATCATTTGTACCTGGAAACCTCAAAATTATGCTTTTGGTTCTTACTGGGTGACTTTGAC
 241 TTAATTTAACACCTGAGCCTCAGTTTTCTCATCTGCCAAATGGGAGTAATAATAATAATCCTTATAAAATTGGGTTCATA
 321 AAGTTTAGAGAAAAGGAATGGAAAGTACCCAGAACTATGCCTGGAGCACGCACGACACACGTACAGTGAGTTGGGAGCCG
 401 TTAGGCTGAATGTTACTGCTTGCCATATGATGTGAAGTACAGCAATATCCCAAGTTCTTGTGACTGAGGGAGATTTTCTG
 481 GAAGGGCCACAGGAGGTTGCGGAGCTTGGATGTTGCCCTTAGTTCTTGTTTAATGTCTCTCTGAATGCAGTTTTAAAATA
 561 GAAAACAAAACTGACTTCTGTAGAAGTTTCCAGAGGGAGGTGCTGTTATCTCGTACCTCCTGGGATGGCGATCCCTACTG
 641 AACGCTTGTGTCTCAGGGTGGACCACTCTGTGTCTGTCTCCAAGCAGAGACCAGTAAAGGAGCCTCCTGGTCCTCAGTGC
 721 GTGACCCTGTCAGTGCTTTCAGGAGACATGTAAGCTTCCTGGGTGAAGGTTGATTTGTACCTTCTGAATCCTGTCACGTG
 801 TAGACATGGGAAACTGACCTATCAGTGTTTTGTGTGTGTAGGTGACTCCCACATACACAGTTGCCATTTTTCTCTCTAAC
 881 TGGGCACCAGTGAACATGCGGGCATGAGGAGTGACTGTGTACCATTTCAGCTGTTTCTTTTCGGGCAGTCCCCTGGTCAG
 961 AGGGGGTGGGGGTGGGGGAGGGGAGAGGGGTACCTAGAACCCAGAGAACATTGGCTTATGCCAGATACCACACCACATCT
1041 GGGCTTACATTCTTGTATCTTTTTTGGTGTGTGGGCGGGGGGGGTGGGGGGCAGTTCAGTGAAGTCTAGAAGACCTGCTG
1121 GACAAATTCTAAAAGAGCTAGAGCTGTAACACTTATTCTTGCATCTTATTAATTTTCTATGATATTTTTTCCTTCTTCGT
1201 AGGGACTTGGGACAATCTGGCTTTGCTGCTTTCTAACTGCTAGGCACCTCTCTCTAACCCTCATTGTCAGAGGGAATTGG
1281 AGGATATCCACAGTCTGTTCCTGTTCTGATATTCTGAGCAGAGAAAAGGCACTAACGGTTCCTCTTAGCTATTTAATTAT
1361 CAGAAGCAAGTAATCTTTCCCCAGATAATATTTTGCCCTAGAAGAAGCCGTGATTTAGCTCTTTTATTGTGCTTACTTGG
1441 TCCAAATACATCTGTGGGGTGTTTTGTCATTTCTTAATGAATGAATCATAGTTATAACCAGGGGCCAAGCTGCCCAAGAG
1521 GCTCTTCAGAGATCATGGATGCTCTCTTTCTGGAAGCTGTGGCCTGATGGAGCAGCCCCATTCCAGGGTCCCATCTGTCC
1601 GGAGTTGTGTATGTCAAGTCCGGCTCAGTCTTTATTTCCAACACTAGCCGTGGTCCTGTGCAGTCAAGCTCTCAGCTAGT
1681 GTTTAGGGCTGTCTGTCAGAAATGGTTATACGTGGGCAAAAGAAGATCTGACAGCTCCTATATACCTTATCTTACTGAAT
1761 TCTTAAACTTTGAACCAGTTCTTCCACTTACTGACTTGTTACCACTGCTGACTTTCTGAAAAGTTTTCCAGTTTTTGTTT
1841 TTTGTTTTTTGTTTTCCAGTAGGGGATTAGAATGTTTAGTCCTACTTAGTAAGAAAAATATTGTATTTTTAATCATTCAT
1921 AGTGCTGGTAAAAAAAAAAAAAAAAAAAAAAAAATTGGGGGGTGGCCGGGCGCAGTGGCTCACACCTGTAATCCCAGCAC
2001 TTTGGGAGGCCAAGGCGGGCGGATCACCTCATGCCTGTAATCCCAGCATTGGGATGGGAGGCTGAGGTGGGTGGATTGCT
2081 TGAGAAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAAATAGAAAACTTAGCTGGGCATGGTGG
2161 CACACGCCTGTAATCCCAGCTACCGGGGAGGCTGAGGCACAAGAATTGCTTGAACTTGGGAGGCAGAGTTTGTAGTGAGC
2241 CAAGATCACGCCACTGCATTCCAGCCTGGCCGACAGTGTGAGACGGTCTCAGAAAAAAAAAGAAAGAAAGAAAGAAAAAG
2321 AAAAAACTTGGGGTAATTTATGTCCAGCTTAAGTACCTGAACAGTTTCCGGAAATGTATATTTTTTTTCTGAGAGGCAAA
2401 GGATGTAAACAGCTTCTAAGTAGCTTTAATGTTTCTGTACAGAAATAAGTTTATCCCTGTAACATTGTGGTAGAGTTTTA
2481 ATACAGTATTTAGTTTTTTATTGGGCTTTTTTAAAAAGTTAACTTTTAACATAGCTGCTCAGGGATTAAATCAGATTGGA
2561 AAACCCATTCTGACTCCACATACTGCTACAAAGAAATACATCGTTGTTTATATTGAGCTGCAGGAGATAGTACACTTTAA
2641 ACTTAAGAAAGTTAAATGTTTCACAATAACATTGCAATATAATCTTCAGCTACTCTCTTTCCATTGGTAAAATCTCTGAT
2721 GGTGTGATAACTCTTTGCCAACCTACGAAACCCATATCTGGAAGAATCACCAGCTCCCGTGAGCAGCTTCATGTAAATAG
2801 ATGCACTCCAAGCAGATTGCATGCCTCAGGTGTTTGTCTTCTAGTAATCATGGAGTGTGCAACACCCAGAGTAACACTAC
2881 AAGGGGCAGGACTGCAAACAGCAGGTCCTGGCTAAAAACCCTTAATGCTGCATTGCTGCCAGTTGTAAAGAGATGCCTGA
2961 ATGGAGGCAAGTTCTGCCCTGTGGGTGAAACTGATGATGTACTGTACTGTCATATATAAATCCACTAAATCCAGCTACCA
3041 GGAACTGCCTGGAACTGTGGCCATGCATTTTTTTTTTTCTTTAAAGACCAGTGTGATAGTAGGCCATGCATCTGAGATAC
3121 GATATTCCTTGGTAACTAGAGGGAGAAAAAAAAATCAAGTAGGTTCAGGCTTATGTTGTATTTTGAGAGTCTGGTTTTAT
3201 TTGAACAGAAATAACTCTACAGAAAGCTCTTGTAAATAATGCTCAAATTTGCACCCGACGATCAAATCCATTAAAAATGA
3281 ATCTTGTATATGAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' aucUUAGAGAUGCCCAUUCACACa 5'
             ||||   |:|   :|||||| 
Target 5' agtAATC---ATG---GAGTGTGc 3'
 2843 - 2860 131.00 -10.30
2 
miRNA  3' aucuuAGAGAUGCCCAUUC-ACACa 5'
               ||||| :  | ||| |||| 
Target 5' gatgcTCTCTTTCTGGAAGCTGTGg 3'
 1538 - 1562 127.00 -11.10
3 
miRNA  3' aucuuAGAGAUGCCCAUUCACACa 5'
               |||:||  |   |||||| 
Target 5' tttttTCTTTAAAGACCAGTGTGa 3'
 3073 - 3096 127.00 -10.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31542054 3 COSMIC
COSN30507256 4 COSMIC
COSN13733061 9 COSMIC
COSN26973364 10 COSMIC
COSN30145534 19 COSMIC
COSN31488115 49 COSMIC
COSN20113371 366 COSMIC
COSN19094138 381 COSMIC
COSN6658343 441 COSMIC
COSN25526548 568 COSMIC
COSN32064189 978 COSMIC
COSN21265525 1136 COSMIC
COSN20113369 1831 COSMIC
COSN27280669 1835 COSMIC
COSN28904745 3068 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1366870205 1 dbSNP
rs1330166243 2 dbSNP
rs375293360 3 dbSNP
rs369666896 4 dbSNP
rs1398611635 5 dbSNP
rs1170384006 6 dbSNP
rs376353729 9 dbSNP
rs766529744 9 dbSNP
rs754832211 13 dbSNP
rs751338811 15 dbSNP
rs372892765 16 dbSNP
rs764025862 17 dbSNP
rs1233684682 19 dbSNP
rs1292663612 25 dbSNP
rs886838071 26 dbSNP
rs756367311 27 dbSNP
rs778692407 33 dbSNP
rs762960523 39 dbSNP
rs1236183855 40 dbSNP
rs147296242 41 dbSNP
rs1312708466 47 dbSNP
rs1217684617 62 dbSNP
rs1384221103 62 dbSNP
rs1386693479 68 dbSNP
rs1026914029 82 dbSNP
rs866851701 84 dbSNP
rs1183788818 93 dbSNP
rs1386627034 98 dbSNP
rs1429439844 104 dbSNP
rs1442225415 113 dbSNP
rs1177927636 125 dbSNP
rs1390648102 130 dbSNP
rs1479455333 131 dbSNP
rs1376988618 138 dbSNP
rs772657839 147 dbSNP
rs1193636980 148 dbSNP
rs1320713774 149 dbSNP
rs771183894 150 dbSNP
rs1434702117 161 dbSNP
rs552049929 164 dbSNP
rs1448475744 166 dbSNP
rs553325228 168 dbSNP
rs566322262 174 dbSNP
rs899727698 183 dbSNP
rs1056716092 188 dbSNP
rs938029176 191 dbSNP
rs1426077441 192 dbSNP
rs112092171 194 dbSNP
rs1281934867 196 dbSNP
rs1464268854 210 dbSNP
rs1203968288 211 dbSNP
rs943316387 216 dbSNP
rs1459647926 226 dbSNP
rs946795841 228 dbSNP
rs529266214 229 dbSNP
rs150515853 245 dbSNP
rs1470824358 276 dbSNP
rs987957862 279 dbSNP
rs1160770154 300 dbSNP
rs1221747048 314 dbSNP
rs1410304756 320 dbSNP
rs934868658 328 dbSNP
rs1457035225 334 dbSNP
rs924759079 342 dbSNP
rs1408583573 343 dbSNP
rs1394472436 352 dbSNP
rs1323467281 355 dbSNP
rs988401551 360 dbSNP
rs1230118075 367 dbSNP
rs978921616 369 dbSNP
rs200806178 370 dbSNP
rs201316422 370 dbSNP
rs78301097 371 dbSNP
rs1433959847 372 dbSNP
rs74456689 372 dbSNP
rs549855656 373 dbSNP
rs202140996 375 dbSNP
rs35049591 375 dbSNP
rs72210048 375 dbSNP
rs1023133095 380 dbSNP
rs1016575676 381 dbSNP
rs1486221960 384 dbSNP
rs141611403 385 dbSNP
rs1401446464 386 dbSNP
rs1431842574 390 dbSNP
rs1168376026 397 dbSNP
rs959698551 399 dbSNP
rs1035470399 400 dbSNP
rs1393226614 402 dbSNP
rs778182453 407 dbSNP
rs1306185076 410 dbSNP
rs1004359293 411 dbSNP
rs1349825618 417 dbSNP
rs756640406 422 dbSNP
rs1025373740 425 dbSNP
rs994112875 427 dbSNP
rs1187688655 432 dbSNP
rs896645678 436 dbSNP
rs753255141 440 dbSNP
rs2074437 441 dbSNP
rs147977554 449 dbSNP
rs1273232606 461 dbSNP
rs1039633764 472 dbSNP
rs1441877932 478 dbSNP
rs1200755724 486 dbSNP
rs1271550859 500 dbSNP
rs1431789027 503 dbSNP
rs1043778123 507 dbSNP
rs1373861381 512 dbSNP
rs780319626 517 dbSNP
rs572971099 533 dbSNP
rs143514102 536 dbSNP
rs1369998703 537 dbSNP
rs1304869496 541 dbSNP
rs1051884425 545 dbSNP
rs542581720 559 dbSNP
rs1052521090 566 dbSNP
rs1247158997 578 dbSNP
rs1327863422 579 dbSNP
rs1225670758 583 dbSNP
rs1383090809 588 dbSNP
rs751720196 589 dbSNP
rs1296296049 590 dbSNP
rs1359499697 598 dbSNP
rs1316665791 600 dbSNP
rs1294602379 605 dbSNP
rs1487751978 606 dbSNP
rs1449860010 609 dbSNP
rs117100367 612 dbSNP
rs557038402 613 dbSNP
rs947522597 621 dbSNP
rs901628302 635 dbSNP
rs1445306207 637 dbSNP
rs1165490727 640 dbSNP
rs753717925 643 dbSNP
rs764074359 644 dbSNP
rs942636626 655 dbSNP
rs1394227720 657 dbSNP
rs796203643 664 dbSNP
rs1432500052 666 dbSNP
rs1319467660 668 dbSNP
rs983776147 669 dbSNP
rs928305928 670 dbSNP
rs1424985693 672 dbSNP
rs951076907 676 dbSNP
rs1309907492 680 dbSNP
rs982446098 681 dbSNP
rs760666920 682 dbSNP
rs1181929250 690 dbSNP
rs1472581252 693 dbSNP
rs1026702125 696 dbSNP
rs1233569171 698 dbSNP
rs1314115001 703 dbSNP
rs995375381 716 dbSNP
rs992599314 719 dbSNP
rs1246433619 720 dbSNP
rs189380471 721 dbSNP
rs1185536217 741 dbSNP
rs1018226974 743 dbSNP
rs1008135150 747 dbSNP
rs891013933 757 dbSNP
rs1361974808 758 dbSNP
rs1052215507 770 dbSNP
rs1226296371 772 dbSNP
rs1355198448 779 dbSNP
rs998825768 784 dbSNP
rs1406397660 790 dbSNP
rs903272524 791 dbSNP
rs1043121817 797 dbSNP
rs947582219 798 dbSNP
rs1443666174 802 dbSNP
rs373321995 806 dbSNP
rs916069461 820 dbSNP
rs1377767248 822 dbSNP
rs1011357264 824 dbSNP
rs1308316189 825 dbSNP
rs1307298738 840 dbSNP
rs892472652 841 dbSNP
rs1367273054 844 dbSNP
rs1161413750 847 dbSNP
rs371080373 849 dbSNP
rs1408968354 853 dbSNP
rs1160385753 854 dbSNP
rs1052826221 855 dbSNP
rs998300727 872 dbSNP
rs577767535 876 dbSNP
rs1251754556 884 dbSNP
rs928864306 885 dbSNP
rs1429704940 890 dbSNP
rs557896141 899 dbSNP
rs951073330 900 dbSNP
rs1490974700 910 dbSNP
rs1299324543 912 dbSNP
rs535185013 922 dbSNP
rs3744711 926 dbSNP
rs1221273677 939 dbSNP
rs1048292439 941 dbSNP
rs973798974 942 dbSNP
rs867176540 943 dbSNP
rs963902468 945 dbSNP
rs918275593 950 dbSNP
rs1326405884 957 dbSNP
rs1287135729 958 dbSNP
rs1224095153 959 dbSNP
rs1205347748 960 dbSNP
rs1347321390 960 dbSNP
rs1291628177 961 dbSNP
rs1435421227 964 dbSNP
rs1346017674 967 dbSNP
rs992873861 972 dbSNP
rs1189181569 973 dbSNP
rs1478877039 973 dbSNP
rs549636126 974 dbSNP
rs1171936346 979 dbSNP
rs1368140863 982 dbSNP
rs1428429123 987 dbSNP
rs535812107 989 dbSNP
rs771702167 990 dbSNP
rs1018133610 995 dbSNP
rs1366645917 997 dbSNP
rs570027757 1015 dbSNP
rs184594316 1028 dbSNP
rs955472183 1031 dbSNP
rs1367195313 1048 dbSNP
rs138715319 1049 dbSNP
rs1177241153 1055 dbSNP
rs1481736833 1057 dbSNP
rs1427738890 1059 dbSNP
rs564204318 1060 dbSNP
rs1190983550 1064 dbSNP
rs1486373558 1065 dbSNP
rs1011158889 1067 dbSNP
rs1242363607 1068 dbSNP
rs1292423734 1069 dbSNP
rs1217562684 1070 dbSNP
rs940392466 1072 dbSNP
rs1267017642 1073 dbSNP
rs909104918 1076 dbSNP
rs999294614 1077 dbSNP
rs77195858 1079 dbSNP
rs180850458 1081 dbSNP
rs1031016537 1083 dbSNP
rs1362455719 1084 dbSNP
rs1322787637 1085 dbSNP
rs1371899612 1085 dbSNP
rs868529429 1085 dbSNP
rs879781810 1085 dbSNP
rs1226517704 1086 dbSNP
rs1447362119 1086 dbSNP
rs1271681350 1091 dbSNP
rs1245832783 1092 dbSNP
rs1433250924 1099 dbSNP
rs1011632446 1119 dbSNP
rs773813697 1136 dbSNP
rs1388165148 1137 dbSNP
rs998582855 1138 dbSNP
rs1474082199 1140 dbSNP
rs901291983 1146 dbSNP
rs1413593083 1148 dbSNP
rs1458104133 1150 dbSNP
rs1386763960 1156 dbSNP
rs894542863 1156 dbSNP
rs1357957198 1159 dbSNP
rs770618079 1164 dbSNP
rs1342314731 1169 dbSNP
rs201214796 1175 dbSNP
rs372857509 1175 dbSNP
rs1429610541 1179 dbSNP
rs748596480 1184 dbSNP
rs1230009629 1191 dbSNP
rs1265953840 1192 dbSNP
rs1328107585 1193 dbSNP
rs749570359 1198 dbSNP
rs928916028 1199 dbSNP
rs1440180705 1203 dbSNP
rs1186150018 1209 dbSNP
rs1237412735 1210 dbSNP
rs1047308773 1232 dbSNP
rs1473180686 1243 dbSNP
rs929654086 1244 dbSNP
rs1456955306 1245 dbSNP
rs559321609 1247 dbSNP
rs1246969462 1252 dbSNP
rs1173376653 1256 dbSNP
rs1048177770 1259 dbSNP
rs973705467 1264 dbSNP
rs929922297 1265 dbSNP
rs1351066890 1268 dbSNP
rs897049558 1271 dbSNP
rs1056823589 1293 dbSNP
rs942443413 1295 dbSNP
rs910932272 1298 dbSNP
rs62072696 1303 dbSNP
rs199589198 1311 dbSNP
rs979854764 1327 dbSNP
rs955225655 1329 dbSNP
rs1031361430 1330 dbSNP
rs978023998 1336 dbSNP
rs1483698593 1337 dbSNP
rs967912331 1338 dbSNP
rs1250155705 1341 dbSNP
rs947078989 1342 dbSNP
rs915432698 1348 dbSNP
rs990028208 1350 dbSNP
rs1477141316 1359 dbSNP
rs1225822786 1365 dbSNP
rs1021601396 1369 dbSNP
rs1364733834 1373 dbSNP
rs1371207742 1380 dbSNP
rs563579293 1383 dbSNP
rs1306091058 1402 dbSNP
rs1369807489 1403 dbSNP
rs1031655729 1410 dbSNP
rs1303082304 1411 dbSNP
rs976819484 1425 dbSNP
rs894572312 1429 dbSNP
rs1343679728 1442 dbSNP
rs1018197127 1461 dbSNP
rs1034389668 1468 dbSNP
rs1273122785 1468 dbSNP
rs1377135863 1469 dbSNP
rs1302308707 1479 dbSNP
rs1210845267 1483 dbSNP
rs1003492768 1488 dbSNP
rs1198416557 1489 dbSNP
rs543403796 1495 dbSNP
rs1463005801 1497 dbSNP
rs907349342 1499 dbSNP
rs1389511248 1501 dbSNP
rs577728480 1504 dbSNP
rs1047791253 1506 dbSNP
rs1295117066 1507 dbSNP
rs1388274462 1508 dbSNP
rs930256169 1508 dbSNP
rs865930449 1512 dbSNP
rs1320798432 1520 dbSNP
rs1429442388 1522 dbSNP
rs898725242 1538 dbSNP
rs1366850402 1541 dbSNP
rs1225550489 1544 dbSNP
rs1389203887 1548 dbSNP
rs1183772793 1553 dbSNP
rs1307450234 1575 dbSNP
rs1446047914 1577 dbSNP
rs1267672860 1592 dbSNP
rs1354670877 1593 dbSNP
rs1209555973 1596 dbSNP
rs1248882861 1600 dbSNP
rs770187858 1601 dbSNP
rs994388501 1602 dbSNP
rs375402610 1605 dbSNP
rs1247465703 1615 dbSNP
rs942309276 1617 dbSNP
rs1166831148 1621 dbSNP
rs1457233320 1622 dbSNP
rs1180754314 1625 dbSNP
rs1159541480 1637 dbSNP
rs1390425052 1642 dbSNP
rs557859028 1649 dbSNP
rs1234470143 1650 dbSNP
rs1379256173 1652 dbSNP
rs189008956 1653 dbSNP
rs185048114 1655 dbSNP
rs938543612 1658 dbSNP
rs1315453830 1661 dbSNP
rs748652868 1665 dbSNP
rs1233086041 1679 dbSNP
rs933848121 1684 dbSNP
rs1044059407 1687 dbSNP
rs923811312 1705 dbSNP
rs1207021357 1710 dbSNP
rs1260289932 1711 dbSNP
rs1292199258 1711 dbSNP
rs978306301 1712 dbSNP
rs764830627 1718 dbSNP
rs1183619402 1727 dbSNP
rs1248496517 1731 dbSNP
rs967941702 1733 dbSNP
rs1022136161 1741 dbSNP
rs868577456 1745 dbSNP
rs1455355216 1746 dbSNP
rs1391980490 1753 dbSNP
rs1359318630 1755 dbSNP
rs1467135638 1755 dbSNP
rs555729354 1756 dbSNP
rs1377646769 1763 dbSNP
rs1414679335 1767 dbSNP
rs1289412979 1771 dbSNP
rs989690162 1775 dbSNP
rs990145372 1776 dbSNP
rs1226858768 1781 dbSNP
rs1306580442 1791 dbSNP
rs958698069 1801 dbSNP
rs1034873068 1804 dbSNP
rs1376177544 1812 dbSNP
rs201794439 1832 dbSNP
rs1485332920 1834 dbSNP
rs3088255 1837 dbSNP
rs397963188 1837 dbSNP
rs58645097 1837 dbSNP
rs1425469103 1840 dbSNP
rs879641388 1841 dbSNP
rs1306677428 1844 dbSNP
rs1434489615 1844 dbSNP
rs375808058 1856 dbSNP
rs573043856 1856 dbSNP
rs924250652 1856 dbSNP
rs1434712857 1857 dbSNP
rs977416917 1859 dbSNP
rs1002944857 1870 dbSNP
rs965561715 1880 dbSNP
rs907250817 1884 dbSNP
rs1279300844 1886 dbSNP
rs1368601380 1893 dbSNP
rs1018249443 1894 dbSNP
rs1299336524 1901 dbSNP
rs1347240472 1909 dbSNP
rs1229158557 1912 dbSNP
rs1276693067 1913 dbSNP
rs1482009420 1914 dbSNP
rs1203580971 1923 dbSNP
rs985412751 1929 dbSNP
rs1394015054 1930 dbSNP
rs1459171186 1930 dbSNP
rs952821463 1941 dbSNP
rs1027481038 1942 dbSNP
rs994047121 1943 dbSNP
rs961508405 1944 dbSNP
rs1025828353 1948 dbSNP
rs1179985135 1952 dbSNP
rs1369164299 1954 dbSNP
rs1002808587 1955 dbSNP
rs1164208215 1955 dbSNP
rs1213888878 1955 dbSNP
rs1219040104 1955 dbSNP
rs1290411949 1955 dbSNP
rs1299848684 1955 dbSNP
rs1323269892 1955 dbSNP
rs1340028961 1955 dbSNP
rs1350804596 1955 dbSNP
rs1370437683 1955 dbSNP
rs1435943475 1955 dbSNP
rs1438961316 1955 dbSNP
rs377645589 1955 dbSNP
rs762484861 1955 dbSNP
rs1422080830 1956 dbSNP
rs1322690134 1958 dbSNP
rs866793473 1959 dbSNP
rs1224426042 1960 dbSNP
rs905751713 1962 dbSNP
rs947834310 1963 dbSNP
rs994704415 1964 dbSNP
rs898756326 1965 dbSNP
rs536048645 1967 dbSNP
rs1038624389 1968 dbSNP
rs192697907 1972 dbSNP
rs556452360 1976 dbSNP
rs1265772777 1979 dbSNP
rs889443359 1983 dbSNP
rs539417568 1986 dbSNP
rs1051173162 2002 dbSNP
rs1053272453 2009 dbSNP
rs1474029909 2015 dbSNP
rs766146772 2016 dbSNP
rs923646718 2017 dbSNP
rs924108440 2019 dbSNP
rs1385381649 2020 dbSNP
rs570543122 2021 dbSNP
rs1400199262 2022 dbSNP
rs1334874654 2027 dbSNP
rs992043380 2030 dbSNP
rs535295473 2033 dbSNP
rs911455636 2037 dbSNP
rs1292497221 2047 dbSNP
rs915200357 2053 dbSNP
rs952707375 2057 dbSNP
rs1286089137 2060 dbSNP
rs374673832 2064 dbSNP
rs1200554032 2068 dbSNP
rs1280094506 2070 dbSNP
rs144736841 2074 dbSNP
rs565865662 2083 dbSNP
rs981823787 2087 dbSNP
rs971506619 2090 dbSNP
rs781709301 2091 dbSNP
rs1473130056 2095 dbSNP
rs548859478 2121 dbSNP
rs866242288 2122 dbSNP
rs969988580 2129 dbSNP
rs1022888130 2136 dbSNP
rs1017219948 2143 dbSNP
rs754956624 2151 dbSNP
rs1266972746 2154 dbSNP
rs1312189224 2155 dbSNP
rs1371029797 2155 dbSNP
rs1205999334 2158 dbSNP
rs1466400517 2162 dbSNP
rs1326549096 2165 dbSNP
rs1266375608 2166 dbSNP
rs1007162284 2167 dbSNP
rs1324888993 2170 dbSNP
rs1233474112 2172 dbSNP
rs1276174916 2178 dbSNP
rs529097338 2184 dbSNP
rs574314025 2185 dbSNP
rs1232850852 2189 dbSNP
rs146815916 2189 dbSNP
rs34078349 2189 dbSNP
rs1050787143 2194 dbSNP
rs1207770361 2197 dbSNP
rs998226355 2204 dbSNP
rs556149843 2205 dbSNP
rs1042530797 2212 dbSNP
rs1199851199 2217 dbSNP
rs543762524 2235 dbSNP
rs1379508418 2237 dbSNP
rs1452677927 2238 dbSNP
rs1173016045 2249 dbSNP
rs1390733462 2250 dbSNP
rs1041219873 2265 dbSNP
rs1390368754 2271 dbSNP
rs946578120 2272 dbSNP
rs780100648 2275 dbSNP
rs115297726 2276 dbSNP
rs758044250 2282 dbSNP
rs1325130949 2284 dbSNP
rs1368248281 2284 dbSNP
rs564111088 2285 dbSNP
rs1279545219 2291 dbSNP
rs1297634541 2293 dbSNP
rs541117131 2298 dbSNP
rs1049974965 2302 dbSNP
rs931540870 2302 dbSNP
rs79029539 2306 dbSNP
rs919938316 2306 dbSNP
rs1269747377 2318 dbSNP
rs575354353 2318 dbSNP
rs748773962 2318 dbSNP
rs961791167 2318 dbSNP
rs1451323655 2328 dbSNP
rs1372373239 2344 dbSNP
rs1458223384 2345 dbSNP
rs927829638 2346 dbSNP
rs1464466724 2348 dbSNP
rs1391867028 2349 dbSNP
rs1376900106 2357 dbSNP
rs981473362 2358 dbSNP
rs1320689821 2362 dbSNP
rs1366737187 2363 dbSNP
rs1384484792 2369 dbSNP
rs1451571909 2370 dbSNP
rs1326289255 2378 dbSNP
rs369455791 2379 dbSNP
rs918717653 2380 dbSNP
rs1188036203 2382 dbSNP
rs1213289156 2389 dbSNP
rs1333012388 2389 dbSNP
rs1268906152 2390 dbSNP
rs1461787942 2390 dbSNP
rs1466318377 2396 dbSNP
rs981312265 2396 dbSNP
rs972794071 2401 dbSNP
rs1424276793 2413 dbSNP
rs1189422547 2435 dbSNP
rs1415356575 2437 dbSNP
rs1280799495 2446 dbSNP
rs1199283135 2455 dbSNP
rs141134695 2456 dbSNP
rs188777786 2459 dbSNP
rs1390319562 2461 dbSNP
rs1022773536 2471 dbSNP
rs1287745264 2481 dbSNP
rs1384932384 2485 dbSNP
rs1007024664 2493 dbSNP
rs1230001194 2498 dbSNP
rs1397089120 2500 dbSNP
rs1295567848 2508 dbSNP
rs145052941 2512 dbSNP
rs1030321830 2519 dbSNP
rs1232993304 2521 dbSNP
rs150371645 2523 dbSNP
rs866241430 2544 dbSNP
rs1260198186 2546 dbSNP
rs750722600 2548 dbSNP
rs1382953540 2549 dbSNP
rs763949644 2566 dbSNP
rs1255212852 2599 dbSNP
rs1020690692 2602 dbSNP
rs1335587399 2603 dbSNP
rs140459852 2610 dbSNP
rs1010623319 2611 dbSNP
rs1416892852 2612 dbSNP
rs773658698 2617 dbSNP
rs1054884414 2620 dbSNP
rs1018639264 2621 dbSNP
rs1467050429 2625 dbSNP
rs111729736 2627 dbSNP
rs752666709 2628 dbSNP
rs1414585498 2629 dbSNP
rs1308962153 2630 dbSNP
rs570304801 2633 dbSNP
rs1046741068 2634 dbSNP
rs1306470014 2642 dbSNP
rs1312833821 2654 dbSNP
rs950102928 2657 dbSNP
rs1236517423 2663 dbSNP
rs918568722 2669 dbSNP
rs972706123 2677 dbSNP
rs931569448 2682 dbSNP
rs941429453 2692 dbSNP
rs112128549 2693 dbSNP
rs985660304 2697 dbSNP
rs1176249574 2700 dbSNP
rs1267537351 2701 dbSNP
rs138439198 2701 dbSNP
rs553926944 2725 dbSNP
rs1171154297 2733 dbSNP
rs940035310 2735 dbSNP
rs1251787526 2745 dbSNP
rs34379199 2745 dbSNP
rs954355675 2746 dbSNP
rs1029939763 2747 dbSNP
rs981531877 2754 dbSNP
rs977397197 2758 dbSNP
rs966960631 2779 dbSNP
rs1227269797 2788 dbSNP
rs773938750 2792 dbSNP
rs1010487616 2793 dbSNP
rs1285460321 2798 dbSNP
rs1347126196 2807 dbSNP
rs1445084445 2808 dbSNP
rs1229044294 2817 dbSNP
rs989972932 2821 dbSNP
rs1203468243 2824 dbSNP
rs1329397379 2828 dbSNP
rs957547193 2841 dbSNP
rs1191261005 2846 dbSNP
rs534203128 2851 dbSNP
rs1251798731 2855 dbSNP
rs893563531 2856 dbSNP
rs35267210 2868 dbSNP
rs1187603612 2870 dbSNP
rs1411561478 2877 dbSNP
rs1368516595 2878 dbSNP
rs1307171792 2880 dbSNP
rs1425598074 2884 dbSNP
rs184476322 2885 dbSNP
rs1031583234 2891 dbSNP
rs1033380078 2899 dbSNP
rs977523241 2900 dbSNP
rs1324041950 2905 dbSNP
rs965746393 2908 dbSNP
rs1370315789 2922 dbSNP
rs1161541431 2929 dbSNP
rs1271860134 2941 dbSNP
rs372647195 2952 dbSNP
rs1290300024 2955 dbSNP
rs1336546713 2959 dbSNP
rs906339602 2964 dbSNP
rs1272055137 2969 dbSNP
rs1464969279 2971 dbSNP
rs1007281921 2976 dbSNP
rs765860562 2979 dbSNP
rs1426407355 2980 dbSNP
rs867302114 2994 dbSNP
rs1244368706 2999 dbSNP
rs1474686750 3004 dbSNP
rs568422649 3014 dbSNP
rs1186355784 3016 dbSNP
rs1185041595 3024 dbSNP
rs78663911 3040 dbSNP
rs1251635976 3042 dbSNP
rs117670809 3047 dbSNP
rs145844622 3048 dbSNP
rs142569054 3050 dbSNP
rs71726215 3050 dbSNP
rs769569169 3050 dbSNP
rs1457861050 3054 dbSNP
rs551989885 3058 dbSNP
rs1343410966 3067 dbSNP
rs1037043890 3078 dbSNP
rs1044835 3079 dbSNP
rs1284633741 3079 dbSNP
rs145350626 3079 dbSNP
rs1231165390 3080 dbSNP
rs1451823602 3083 dbSNP
rs1292301531 3086 dbSNP
rs941334442 3110 dbSNP
rs910009140 3113 dbSNP
rs1291527659 3117 dbSNP
rs1224993665 3120 dbSNP
rs772918768 3121 dbSNP
rs1215683390 3123 dbSNP
rs1355094365 3124 dbSNP
rs1288394809 3125 dbSNP
rs770132802 3128 dbSNP
rs548679968 3129 dbSNP
rs1287507608 3155 dbSNP
rs1417440903 3155 dbSNP
rs1436852764 3156 dbSNP
rs940232993 3156 dbSNP
rs907207511 3170 dbSNP
rs1045740981 3176 dbSNP
rs985526064 3189 dbSNP
rs1321775441 3193 dbSNP
rs948798180 3211 dbSNP
rs1412736978 3214 dbSNP
rs1404967814 3219 dbSNP
rs1311996821 3225 dbSNP
rs1385818594 3232 dbSNP
rs1240712025 3237 dbSNP
rs1277335265 3240 dbSNP
rs915985910 3244 dbSNP
rs192028149 3246 dbSNP
rs1281702581 3252 dbSNP
rs922776017 3256 dbSNP
rs777057731 3257 dbSNP
rs530286505 3259 dbSNP
rs967365231 3263 dbSNP
rs1438676149 3279 dbSNP
rs1184232860 3282 dbSNP
rs1411782803 3283 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 56919.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aucuuagagaugcccauUCACACa 5'
                           |||||| 
Target 5' --------------accAGUGUGa 3'
 		1 - 10
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000225296.3 | 3UTR | ACCAGUGUGAUAGUAGGCCAU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
111 hsa-miR-216b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT071722 CCNK cyclin K 2 2
MIRT074768 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT101407 SSR1 signal sequence receptor subunit 1 2 2
MIRT241289 AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2 4
MIRT268292 CCND1 cyclin D1 2 8
MIRT445347 IFNA6 interferon alpha 6 2 2
MIRT446663 MXI1 MAX interactor 1, dimerization protein 2 4
MIRT447595 MSH3 mutS homolog 3 2 2
MIRT448485 SEMA4F ssemaphorin 4F 2 2
MIRT450309 DRAXIN dorsal inhibitory axon guidance protein 2 2
MIRT451850 TXNDC5 thioredoxin domain containing 5 2 2
MIRT483613 SMC5 structural maintenance of chromosomes 5 2 2
MIRT485633 EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2 2
MIRT499766 CIRH1A UTP4, small subunit processome component 2 6
MIRT503337 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT513007 MAN1A2 mannosidase alpha class 1A member 2 2 2
MIRT513529 RHOQ ras homolog family member Q 2 4
MIRT521499 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT524335 CRK CRK proto-oncogene, adaptor protein 2 4
MIRT524731 BRI3BP BRI3 binding protein 2 8
MIRT525326 SNX29 sorting nexin 29 2 2
MIRT526264 CCDC169 coiled-coil domain containing 169 2 2
MIRT527428 NRL neural retina leucine zipper 2 2
MIRT527512 ZNF134 zinc finger protein 134 2 2
MIRT528881 ATF3 activating transcription factor 3 2 2
MIRT529578 IGBP1 immunoglobulin binding protein 1 2 4
MIRT531122 ZYG11B zyg-11 family member B, cell cycle regulator 2 2
MIRT531341 TGIF2LX TGFB induced factor homeobox 2 like, X-linked 2 2
MIRT532433 DHX33 DEAH-box helicase 33 2 2
MIRT534032 STX7 syntaxin 7 2 2
MIRT534538 SACS sacsin molecular chaperone 2 4
MIRT538886 BRWD3 bromodomain and WD repeat domain containing 3 2 2
MIRT539628 CD19 CD19 molecule 2 8
MIRT540327 ATAT1 alpha tubulin acetyltransferase 1 2 8
MIRT540353 OCLN occludin 2 6
MIRT540699 ATG10 autophagy related 10 2 4
MIRT541033 STRBP spermatid perinuclear RNA binding protein 2 8
MIRT541945 NBPF10 NBPF member 10 2 4
MIRT543505 PLS1 plastin 1 2 2
MIRT551164 UBTF upstream binding transcription factor, RNA polymerase I 2 4
MIRT551790 ZNF117 zinc finger protein 117 2 4
MIRT553227 TWF1 twinfilin actin binding protein 1 2 2
MIRT559622 AKIRIN2 akirin 2 2 2
MIRT559719 ADORA2B adenosine A2b receptor 2 2
MIRT564600 ZNF781 zinc finger protein 781 2 2
MIRT567015 KLHL15 kelch like family member 15 2 2
MIRT569564 C7orf26 chromosome 7 open reading frame 26 2 2
MIRT572155 DDX3X DEAD-box helicase 3, X-linked 2 2
MIRT575399 Zdhhc22 zinc finger, DHHC-type containing 22 2 5
MIRT607322 PKNOX1 PBX/knotted 1 homeobox 1 2 4
MIRT607953 NFAM1 NFAT activating protein with ITAM motif 1 2 10
MIRT607979 ZDHHC22 zinc finger DHHC-type containing 22 2 7
MIRT609145 ZNF610 zinc finger protein 610 2 4
MIRT609206 GOSR2 golgi SNAP receptor complex member 2 2 4
MIRT609338 HRASLS5 HRAS like suppressor family member 5 2 2
MIRT609725 KIF5C kinesin family member 5C 2 4
MIRT610014 MED24 mediator complex subunit 24 2 4
MIRT610407 TMEM245 transmembrane protein 245 2 2
MIRT610559 NBPF14 NBPF member 14 2 2
MIRT611291 PAGR1 PAXIP1 associated glutamate rich protein 1 2 2
MIRT611399 ATP9A ATPase phospholipid transporting 9A (putative) 2 2
MIRT611432 C11orf45 chromosome 11 open reading frame 45 2 4
MIRT611710 SLFN13 schlafen family member 13 2 2
MIRT611721 ANK3 ankyrin 3 2 2
MIRT611830 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 4
MIRT611977 ZNF175 zinc finger protein 175 2 2
MIRT612073 CEP135 centrosomal protein 135 2 4
MIRT612195 CCDC77 coiled-coil domain containing 77 2 2
MIRT612320 UBE2H ubiquitin conjugating enzyme E2 H 2 2
MIRT612354 TNRC6C trinucleotide repeat containing 6C 2 4
MIRT612635 PTEN phosphatase and tensin homolog 2 2
MIRT612773 MLXIP MLX interacting protein 2 4
MIRT612788 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 4
MIRT612853 JAZF1 JAZF zinc finger 1 2 2
MIRT612965 GID4 GID complex subunit 4 homolog 2 6
MIRT613132 DUSP6 dual specificity phosphatase 6 2 2
MIRT613388 AAK1 AP2 associated kinase 1 2 2
MIRT615058 CRY2 cryptochrome circadian clock 2 2 4
MIRT616046 HSPA12B heat shock protein family A (Hsp70) member 12B 2 2
MIRT617962 SEPT9 septin 9 2 2
MIRT618413 ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 2 2
MIRT622448 RNF213 ring finger protein 213 2 2
MIRT623611 IPCEF1 interaction protein for cytohesin exchange factors 1 2 2
MIRT625709 SHROOM1 shroom family member 1 2 2
MIRT630646 ELK1 ELK1, ETS transcription factor 2 2
MIRT630970 KIAA2022 neurite extension and migration factor 2 2
MIRT631003 SPAG7 sperm associated antigen 7 2 2
MIRT640385 EMC1 ER membrane protein complex subunit 1 2 4
MIRT641064 WBSCR17 polypeptide N-acetylgalactosaminyltransferase 17 2 2
MIRT641780 ZDHHC7 zinc finger DHHC-type containing 7 2 4
MIRT646310 MPHOSPH8 M-phase phosphoprotein 8 2 2
MIRT646624 CENPL centromere protein L 2 2
MIRT659653 CDH2 cadherin 2 2 2
MIRT666161 SP1 Sp1 transcription factor 2 2
MIRT667638 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT668988 CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion 2 2
MIRT680949 PLCXD1 phosphatidylinositol specific phospholipase C X domain containing 1 2 2
MIRT695238 PBK PDZ binding kinase 2 2
MIRT700036 RPL22 ribosomal protein L22 2 2
MIRT707685 GPR50 G protein-coupled receptor 50 2 2
MIRT709324 HMBOX1 homeobox containing 1 2 2
MIRT710176 MTRF1L mitochondrial translational release factor 1 like 2 2
MIRT712007 F9 coagulation factor IX 2 2
MIRT714219 C10orf71 chromosome 10 open reading frame 71 2 2
MIRT714496 HSPA4 heat shock protein family A (Hsp70) member 4 2 2
MIRT714575 GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2 2
MIRT715982 TFRC transferrin receptor 2 2
MIRT717870 TRAPPC3L trafficking protein particle complex 3 like 2 2
MIRT718289 MINA ribosomal oxygenase 2 2 2
MIRT725200 PTRF caveolae associated protein 1 2 2
MIRT737338 TPX2 TPX2, microtubule nucleation factor 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-216b Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-216b 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) NULL 15625 Microarray embryos 22921993 2012 up-regulated
miR-216b Reversine NULL 210332 Microarray C2C12 myoblast cells 24513286 2014 up-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Microarray human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Hydroxycamptothecin (HCPT) NULL 97226 Quantitative real-time PCR human Tenon's fibroblasts (HTFs) 24681041 2014 down-regulated
miR-216b Curcumin NULL 969516 Quantitative real-time PCR Y79 RB cells. 22510010 2012 down-regulated
miR-216b Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-216b Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-216b Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-216b-3p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-216b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-216b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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