ID	Duplex structure	Position	Score	MFE
1	miRNA 3' ggAGA-UCAUUU-AUACAGUCGua 5' ||| | |||| || |||||| Target 5' gaTCTAATTAAATTAGGTCAGCct 3'	710 - 733	148.00	-10.80
2	miRNA 3' ggAGAUCAUUUAUACAGUCGua 5' |:|:|| | ||||| | Target 5' caTTTGGTTCTTCTGTCAACtt 3'	331 - 352	108.00	-6.70
3	miRNA 3' ggAG-AUCA-UUUAUACAGUCGUa 5' || |:|| :|| | ||::| | Target 5' aaTCATGGTGGAAAAAGTTGGAAa 3'	166 - 189	96.00	-5.02

Mutant ID	Mutant Position	Mutant Source
COSM3693700	1	COSMIC
COSM4675234	1	COSMIC
COSN8868683	5	COSMIC
COSN31575936	13	COSMIC
COSN24307034	14	COSMIC
COSN30145924	14	COSMIC
COSN30532502	18	COSMIC
COSN26972139	53	COSMIC
COSN26972141	65	COSMIC
COSN26972140	73	COSMIC
COSN15665045	76	COSMIC
COSN30157292	102	COSMIC
COSN28866525	154	COSMIC
COSN31599966	243	COSMIC
COSN30280737	276	COSMIC
COSN26425442	668	COSMIC
COSN23211868	797	COSMIC
COSN22323576	820	COSMIC
COSN16283627	1006	COSMIC
COSN24931987	1051	COSMIC
COSN2509820	1296	COSMIC
COSN7061437	1603	COSMIC
COSN21457430	1630	COSMIC
COSN21527020	1743	COSMIC
COSN20623868	1791	COSMIC
COSN30300271	1962	COSMIC
COSN30031630	2024	COSMIC
COSN1250840	2204	COSMIC
COSN15605020	2523	COSMIC
COSN27231766	2597	COSMIC
COSN27304660	2597	COSMIC
COSN7098499	2635	COSMIC

Mutant ID	Mutant Position	Mutant Source
rs759604263	2	dbSNP
rs767553332	5	dbSNP
rs546236855	7	dbSNP
rs1251434541	8	dbSNP
rs181401266	13	dbSNP
rs750199023	14	dbSNP
rs757046491	16	dbSNP
rs758269154	17	dbSNP
rs1257230490	19	dbSNP
rs779791984	21	dbSNP
rs780906370	22	dbSNP
rs751311711	24	dbSNP
rs538212301	28	dbSNP
rs201838541	29	dbSNP
rs372870703	30	dbSNP
rs185706466	31	dbSNP
rs1284643125	35	dbSNP
rs778284558	36	dbSNP
rs749587691	37	dbSNP
rs1332711693	43	dbSNP
rs771299882	46	dbSNP
rs149041179	49	dbSNP
rs375719269	50	dbSNP
rs760835133	52	dbSNP
rs6024853	53	dbSNP
rs542730432	54	dbSNP
rs143018521	56	dbSNP
rs1317650555	59	dbSNP
rs1316341908	64	dbSNP
rs1402481432	72	dbSNP
rs1409358190	73	dbSNP
rs749112247	80	dbSNP
rs938131571	81	dbSNP
rs1313533420	82	dbSNP
rs944412005	86	dbSNP
rs768650822	92	dbSNP
rs148184670	96	dbSNP
rs545396193	97	dbSNP
rs1261961780	99	dbSNP
rs900254779	102	dbSNP
rs773966690	103	dbSNP
rs1448159082	104	dbSNP
rs1348029294	114	dbSNP
rs1218564605	119	dbSNP
rs1321242770	120	dbSNP
rs996002472	120	dbSNP
rs1224406164	121	dbSNP
rs761638765	129	dbSNP
rs902740376	133	dbSNP
rs1268568346	135	dbSNP
rs1204215099	139	dbSNP
rs887639174	143	dbSNP
rs1345845474	145	dbSNP
rs1009500268	148	dbSNP
rs565582750	159	dbSNP
rs1201269543	165	dbSNP
rs1014882900	189	dbSNP
rs1477679001	189	dbSNP
rs900655799	191	dbSNP
rs995974759	192	dbSNP
rs1422482125	194	dbSNP
rs1184347988	199	dbSNP
rs1027357474	208	dbSNP
rs773481374	210	dbSNP
rs531073440	211	dbSNP
rs115138879	215	dbSNP
rs1004470910	217	dbSNP
rs190240313	218	dbSNP
rs1264882366	221	dbSNP
rs546045358	224	dbSNP
rs1317008620	226	dbSNP
rs981746716	229	dbSNP
rs1180212486	235	dbSNP
rs1271215922	237	dbSNP
rs1216542373	242	dbSNP
rs140219472	243	dbSNP
rs958775064	244	dbSNP
rs546273916	250	dbSNP
rs16979884	253	dbSNP
rs1450473655	262	dbSNP
rs538250906	266	dbSNP
rs182315222	267	dbSNP
rs1465447648	279	dbSNP
rs1033577887	287	dbSNP
rs867533925	294	dbSNP
rs1416213659	297	dbSNP
rs75407746	299	dbSNP
rs1042390502	301	dbSNP
rs1411267213	322	dbSNP
rs1405979536	328	dbSNP
rs989016548	333	dbSNP
rs765801662	338	dbSNP
rs923921154	343	dbSNP
rs1244907849	347	dbSNP
rs1184115379	354	dbSNP
rs1457203718	355	dbSNP
rs944339976	358	dbSNP
rs146945258	362	dbSNP
rs1308320852	365	dbSNP
rs1289382648	368	dbSNP
rs752969917	375	dbSNP
rs931703769	376	dbSNP
rs1048842161	377	dbSNP
rs887597949	377	dbSNP
rs554775062	387	dbSNP
rs7806	389	dbSNP
rs1346761225	398	dbSNP
rs533942892	400	dbSNP
rs996710027	407	dbSNP
rs1354757112	411	dbSNP
rs1048805628	413	dbSNP
rs1162470410	417	dbSNP
rs780974195	418	dbSNP
rs1458104017	420	dbSNP
rs1386551729	426	dbSNP
rs745582705	433	dbSNP
rs1418406786	435	dbSNP
rs1014234593	436	dbSNP
rs6092312	437	dbSNP
rs1436997340	445	dbSNP
rs1268468228	446	dbSNP
rs1220524113	447	dbSNP
rs1024714785	458	dbSNP
rs1247505572	461	dbSNP
rs905887209	463	dbSNP
rs1315686018	476	dbSNP
rs755831910	477	dbSNP
rs1309738751	480	dbSNP
rs779371347	481	dbSNP
rs6099131	489	dbSNP
rs1014566326	498	dbSNP
rs1002024153	499	dbSNP
rs1367329001	520	dbSNP
rs1302219759	524	dbSNP
rs1402682397	530	dbSNP
rs1033133448	533	dbSNP
rs1481575620	534	dbSNP
rs748850614	535	dbSNP
rs1303250602	536	dbSNP
rs13043522	538	dbSNP
rs1452377822	539	dbSNP
rs1362001862	541	dbSNP
rs1161131581	542	dbSNP
rs139284561	555	dbSNP
rs573328904	556	dbSNP
rs1428335072	563	dbSNP
rs1002825360	564	dbSNP
rs1428691377	566	dbSNP
rs1034675244	570	dbSNP
rs1269810555	574	dbSNP
rs1466554533	577	dbSNP
rs1170124671	585	dbSNP
rs1204663201	589	dbSNP
rs1020472957	594	dbSNP
rs771516386	597	dbSNP
rs966282200	598	dbSNP
rs976382963	600	dbSNP
rs921590280	606	dbSNP
rs1225677813	607	dbSNP
rs78996198	609	dbSNP
rs186054340	610	dbSNP
rs989955901	611	dbSNP
rs1332402609	614	dbSNP
rs1382128052	617	dbSNP
rs575940634	621	dbSNP
rs544557612	633	dbSNP
rs1282047961	634	dbSNP
rs1405147500	642	dbSNP
rs761037856	643	dbSNP
rs1174023910	645	dbSNP
rs143206308	648	dbSNP
rs978159646	650	dbSNP
rs530252437	655	dbSNP
rs924000183	658	dbSNP
rs940481388	687	dbSNP
rs1263903746	694	dbSNP
rs774397035	697	dbSNP
rs1036209670	705	dbSNP
rs1249517722	708	dbSNP
rs1461279400	708	dbSNP
rs896349336	709	dbSNP
rs117639398	710	dbSNP
rs976364761	711	dbSNP
rs1324648434	718	dbSNP
rs561071975	725	dbSNP
rs1210200194	735	dbSNP
rs1226236029	738	dbSNP
rs777151702	740	dbSNP
rs932164883	750	dbSNP
rs1297070862	751	dbSNP
rs1382251444	755	dbSNP
rs1381982364	763	dbSNP
rs1490883226	765	dbSNP
rs1049195578	766	dbSNP
rs1268508001	775	dbSNP
rs1470866479	778	dbSNP
rs887927504	779	dbSNP
rs564474792	780	dbSNP
rs1374950150	786	dbSNP
rs1444011765	787	dbSNP
rs893242944	787	dbSNP
rs532067117	789	dbSNP
rs760216162	799	dbSNP
rs1020389499	801	dbSNP
rs114324599	815	dbSNP
rs1337066404	819	dbSNP
rs568735929	820	dbSNP
rs147543356	821	dbSNP
rs1454480414	829	dbSNP
rs765704609	841	dbSNP
rs1422313980	842	dbSNP
rs1302125978	843	dbSNP
rs376796723	844	dbSNP
rs1340790343	845	dbSNP
rs1398909617	848	dbSNP
rs1168648479	853	dbSNP
rs1401308032	863	dbSNP
rs1383459764	883	dbSNP
rs1166065850	894	dbSNP
rs1301261444	895	dbSNP
rs1445746387	899	dbSNP
rs1292895281	901	dbSNP
rs1439856352	902	dbSNP
rs1252249853	914	dbSNP
rs1325726909	918	dbSNP
rs62209417	919	dbSNP
rs908933368	920	dbSNP
rs953121385	920	dbSNP
rs984490826	920	dbSNP
rs75370577	921	dbSNP
rs548201607	922	dbSNP
rs1266949537	934	dbSNP
rs1356976769	935	dbSNP
rs1337291405	939	dbSNP
rs1308939340	962	dbSNP
rs1404537746	967	dbSNP
rs894362005	974	dbSNP
rs1221518401	980	dbSNP
rs568319364	981	dbSNP
rs949282900	986	dbSNP
rs1206910299	987	dbSNP
rs1157284358	989	dbSNP
rs1471394910	991	dbSNP
rs1364705821	995	dbSNP
rs1327547761	1005	dbSNP
rs8125654	1006	dbSNP
rs1428397089	1010	dbSNP
rs569511474	1012	dbSNP
rs1451618102	1021	dbSNP
rs926564383	1024	dbSNP
rs1203313784	1026	dbSNP
rs1021498038	1027	dbSNP
rs1288728024	1038	dbSNP
rs1387689692	1045	dbSNP
rs200972527	1046	dbSNP
rs370302677	1046	dbSNP
rs762079207	1047	dbSNP
rs1285358809	1050	dbSNP
rs937316934	1055	dbSNP
rs1344674756	1058	dbSNP
rs373493200	1062	dbSNP
rs1316890575	1066	dbSNP
rs1163421127	1068	dbSNP
rs1360756919	1069	dbSNP
rs1176198165	1071	dbSNP
rs191006272	1076	dbSNP
rs1286546819	1077	dbSNP
rs1201115955	1078	dbSNP
rs1383660534	1080	dbSNP
rs1240985882	1081	dbSNP
rs1396152249	1083	dbSNP
rs142136389	1083	dbSNP
rs1165686412	1086	dbSNP
rs1177846150	1086	dbSNP
rs1182899648	1086	dbSNP
rs1210498127	1086	dbSNP
rs1244722109	1086	dbSNP
rs1268647896	1086	dbSNP
rs1317650302	1086	dbSNP
rs1408747706	1086	dbSNP
rs1414662876	1086	dbSNP
rs1418296520	1086	dbSNP
rs1450985797	1086	dbSNP
rs1459867099	1086	dbSNP
rs1476071258	1086	dbSNP
rs71198364	1086	dbSNP
rs754496445	1086	dbSNP
rs768901777	1086	dbSNP
rs1317033070	1088	dbSNP
rs1380572905	1089	dbSNP
rs1054401286	1098	dbSNP
rs1244952194	1106	dbSNP
rs1309730536	1111	dbSNP
rs1214607794	1112	dbSNP
rs6024854	1113	dbSNP
rs1241484559	1114	dbSNP
rs6024855	1115	dbSNP
rs967197953	1117	dbSNP
rs1201150747	1119	dbSNP
rs1245507818	1120	dbSNP
rs1460416732	1121	dbSNP
rs1213148613	1122	dbSNP
rs1183313991	1124	dbSNP
rs1385501728	1125	dbSNP
rs181404945	1127	dbSNP
rs887811596	1128	dbSNP
rs1441887697	1129	dbSNP
rs1430258731	1133	dbSNP
rs1420464831	1141	dbSNP
rs375639343	1151	dbSNP
rs1031466050	1152	dbSNP
rs1390251453	1152	dbSNP
rs1466097413	1162	dbSNP
rs1338196193	1164	dbSNP
rs1403737865	1169	dbSNP
rs1002167883	1170	dbSNP
rs539133492	1172	dbSNP
rs1451829168	1175	dbSNP
rs976460723	1181	dbSNP
rs922226672	1182	dbSNP
rs1206880066	1186	dbSNP
rs1010271848	1192	dbSNP
rs1041815934	1194	dbSNP
rs1243812356	1198	dbSNP
rs932260157	1200	dbSNP
rs1316623899	1202	dbSNP
rs1313985316	1207	dbSNP
rs185543416	1209	dbSNP
rs901984160	1215	dbSNP
rs909417952	1218	dbSNP
rs565960052	1219	dbSNP
rs1372328034	1220	dbSNP
rs1036113438	1221	dbSNP
rs1321953641	1225	dbSNP
rs906910593	1228	dbSNP
rs938381696	1229	dbSNP
rs1481804222	1230	dbSNP
rs190644186	1231	dbSNP
rs1405478646	1236	dbSNP
rs1184668783	1244	dbSNP
rs1249361475	1247	dbSNP
rs1268402545	1254	dbSNP
rs11700131	1255	dbSNP
rs1220360785	1256	dbSNP
rs1490845563	1259	dbSNP
rs1433421097	1262	dbSNP
rs544560640	1268	dbSNP
rs1426631365	1269	dbSNP
rs953667691	1270	dbSNP
rs1011535325	1271	dbSNP
rs1469183962	1273	dbSNP
rs1315550061	1291	dbSNP
rs1309581311	1294	dbSNP
rs182932972	1295	dbSNP
rs760833370	1297	dbSNP
rs1350732767	1301	dbSNP
rs903021479	1302	dbSNP
rs1369089049	1307	dbSNP
rs1439749137	1309	dbSNP
rs1015919955	1311	dbSNP
rs961746053	1321	dbSNP
rs1343309845	1333	dbSNP
rs998654698	1335	dbSNP
rs1457516854	1339	dbSNP
rs1428881300	1345	dbSNP
rs1031098846	1349	dbSNP
rs971800433	1349	dbSNP
rs970928978	1356	dbSNP
rs1186497419	1358	dbSNP
rs980649673	1362	dbSNP
rs1270503168	1365	dbSNP
rs926506060	1366	dbSNP
rs1323258388	1376	dbSNP
rs1262187736	1381	dbSNP
rs1372802287	1387	dbSNP
rs766649389	1391	dbSNP
rs1285231719	1392	dbSNP
rs997591293	1393	dbSNP
rs1381126039	1397	dbSNP
rs1029436132	1398	dbSNP
rs1343749371	1399	dbSNP
rs953370500	1400	dbSNP
rs1166713351	1402	dbSNP
rs1053667708	1408	dbSNP
rs985045599	1410	dbSNP
rs776536500	1420	dbSNP
rs962191266	1421	dbSNP
rs574752068	1425	dbSNP
rs1467756112	1428	dbSNP
rs1378376181	1429	dbSNP
rs901943966	1430	dbSNP
rs933454395	1433	dbSNP
rs1309839757	1435	dbSNP
rs928803694	1442	dbSNP
rs1461174494	1443	dbSNP
rs1415201508	1453	dbSNP
rs938461562	1457	dbSNP
rs1055542879	1458	dbSNP
rs1202489443	1460	dbSNP
rs1050602876	1462	dbSNP
rs1484046111	1462	dbSNP
rs541038999	1462	dbSNP
rs1339435129	1463	dbSNP
rs1251106296	1464	dbSNP
rs534851859	1469	dbSNP
rs10470034	1472	dbSNP
rs1266389163	1479	dbSNP
rs1334474699	1479	dbSNP
rs1397490219	1487	dbSNP
rs189120466	1502	dbSNP
rs1016560516	1503	dbSNP
rs897461858	1504	dbSNP
rs1193837415	1505	dbSNP
rs765636642	1510	dbSNP
rs993167666	1511	dbSNP
rs1408153614	1512	dbSNP
rs1043004426	1513	dbSNP
rs1169405930	1517	dbSNP
rs903074336	1520	dbSNP
rs998717990	1521	dbSNP
rs1443298276	1523	dbSNP
rs1256491794	1525	dbSNP
rs1194870272	1528	dbSNP
rs1041299095	1530	dbSNP
rs1276132183	1531	dbSNP
rs900993375	1541	dbSNP
rs149630806	1542	dbSNP
rs1404395453	1543	dbSNP
rs1270856018	1544	dbSNP
rs1340836201	1550	dbSNP
rs532102357	1554	dbSNP
rs1213357415	1556	dbSNP
rs57790792	1557	dbSNP
rs1360590198	1558	dbSNP
rs1225234231	1564	dbSNP
rs1308745593	1565	dbSNP
rs1424020182	1566	dbSNP
rs1364268681	1567	dbSNP
rs1006141951	1570	dbSNP
rs1016482270	1575	dbSNP
rs962295859	1576	dbSNP
rs763401814	1581	dbSNP
rs972331148	1583	dbSNP
rs1471420602	1584	dbSNP
rs928832336	1590	dbSNP
rs1243350705	1593	dbSNP
rs568559980	1598	dbSNP
rs960234588	1601	dbSNP
rs991650518	1602	dbSNP
rs946025404	1603	dbSNP
rs977404822	1605	dbSNP
rs562566138	1606	dbSNP
rs947049324	1610	dbSNP
rs933402112	1624	dbSNP
rs531232463	1625	dbSNP
rs924254973	1626	dbSNP
rs1289161153	1629	dbSNP
rs1404475342	1630	dbSNP
rs1326159260	1635	dbSNP
rs548125431	1636	dbSNP
rs1384815790	1641	dbSNP
rs1040958607	1642	dbSNP
rs1459094543	1650	dbSNP
rs901039840	1652	dbSNP
rs1182442748	1654	dbSNP
rs11905070	1654	dbSNP
rs1037919754	1656	dbSNP
rs898099090	1662	dbSNP
rs11905108	1669	dbSNP
rs796149665	1671	dbSNP
rs192078950	1672	dbSNP
rs1269085102	1675	dbSNP
rs8183916	1676	dbSNP
rs1223102189	1681	dbSNP
rs889168274	1683	dbSNP
rs6024856	1685	dbSNP
rs1016249651	1688	dbSNP
rs1437235854	1698	dbSNP
rs539170308	1702	dbSNP
rs989291129	1703	dbSNP
rs1020798524	1706	dbSNP
rs966586007	1708	dbSNP
rs558799067	1722	dbSNP
rs897819950	1723	dbSNP
rs183972217	1725	dbSNP
rs370644175	1726	dbSNP
rs111748077	1727	dbSNP
rs1478035394	1729	dbSNP
rs375097993	1730	dbSNP
rs1022740785	1746	dbSNP
rs968480252	1747	dbSNP
rs910630871	1748	dbSNP
rs1214508963	1750	dbSNP
rs879747580	1751	dbSNP
rs924305820	1752	dbSNP
rs757298599	1762	dbSNP
rs977076558	1763	dbSNP
rs1384408886	1765	dbSNP
rs922508212	1769	dbSNP
rs1440945456	1770	dbSNP
rs932489040	1774	dbSNP
rs1280923966	1775	dbSNP
rs1049525875	1776	dbSNP
rs368399942	1777	dbSNP
rs888268481	1778	dbSNP
rs778904970	1779	dbSNP
rs1410487826	1783	dbSNP
rs1231225001	1791	dbSNP
rs1366490122	1791	dbSNP
rs1037751117	1792	dbSNP
rs1399017557	1794	dbSNP
rs1446187078	1795	dbSNP
rs753268091	1799	dbSNP
rs1335763791	1808	dbSNP
rs745423038	1811	dbSNP
rs191255529	1812	dbSNP
rs896047747	1818	dbSNP
rs184031054	1821	dbSNP
rs6024857	1824	dbSNP
rs1023166495	1831	dbSNP
rs968865390	1834	dbSNP
rs553978122	1838	dbSNP
rs1471657202	1839	dbSNP
rs906163485	1842	dbSNP
rs1382531870	1844	dbSNP
rs533326032	1845	dbSNP
rs115852666	1849	dbSNP
rs1280898250	1852	dbSNP
rs1348186837	1855	dbSNP
rs1222645555	1861	dbSNP
rs1314890024	1863	dbSNP
rs1031386248	1866	dbSNP
rs376126138	1869	dbSNP
rs1381793690	1879	dbSNP
rs976414049	1880	dbSNP
rs186842925	1882	dbSNP
rs1201709523	1888	dbSNP
rs932606841	1895	dbSNP
rs985337585	1896	dbSNP
rs1020725094	1902	dbSNP
rs1305676927	1903	dbSNP
rs116236411	1907	dbSNP
rs1371106012	1909	dbSNP
rs56269601	1910	dbSNP
rs1163978924	1919	dbSNP
rs1403434986	1926	dbSNP
rs1415664239	1927	dbSNP
rs1030001283	1931	dbSNP
rs1472402948	1936	dbSNP
rs576049608	1938	dbSNP
rs954695146	1940	dbSNP
rs748016927	1942	dbSNP
rs1483414727	1943	dbSNP
rs1291772717	1948	dbSNP
rs1183803435	1951	dbSNP
rs1219969089	1953	dbSNP
rs1323931755	1961	dbSNP
rs1291064453	1963	dbSNP
rs1223538761	1965	dbSNP
rs1349505140	1976	dbSNP
rs1286014700	1977	dbSNP
rs772013444	1986	dbSNP
rs777498713	1988	dbSNP
rs541503813	1991	dbSNP
rs1292915055	1993	dbSNP
rs986557099	2002	dbSNP
rs1351502620	2008	dbSNP
rs977204812	2023	dbSNP
rs1165221017	2030	dbSNP
rs1234804531	2032	dbSNP
rs1456454388	2034	dbSNP
rs941160598	2037	dbSNP
rs1468812561	2039	dbSNP
rs963445135	2044	dbSNP
rs746839901	2045	dbSNP
rs1430111758	2056	dbSNP
rs55853012	2064	dbSNP
rs185297883	2065	dbSNP
rs547699347	2068	dbSNP
rs1247736750	2070	dbSNP
rs895792704	2072	dbSNP
rs1410877809	2073	dbSNP
rs1331303620	2097	dbSNP
rs1327512101	2100	dbSNP
rs1046602833	2101	dbSNP
rs776957319	2103	dbSNP
rs1329358376	2104	dbSNP
rs1300023348	2109	dbSNP
rs542424714	2111	dbSNP
rs1283310334	2113	dbSNP
rs1055185310	2118	dbSNP
rs1294028443	2127	dbSNP
rs1434178145	2129	dbSNP
rs1346822087	2132	dbSNP
rs1322863952	2139	dbSNP
rs562095741	2146	dbSNP
rs1377244207	2148	dbSNP
rs775716359	2150	dbSNP
rs1262426792	2154	dbSNP
rs1010608694	2155	dbSNP
rs564339720	2156	dbSNP
rs1426560980	2159	dbSNP
rs1340054357	2160	dbSNP
rs533185336	2171	dbSNP
rs1463859612	2173	dbSNP
rs1042153413	2182	dbSNP
rs902321560	2184	dbSNP
rs1000331001	2200	dbSNP
rs549906113	2203	dbSNP
rs1230509994	2204	dbSNP
rs1313434960	2212	dbSNP
rs1301942357	2213	dbSNP
rs1270630709	2214	dbSNP
rs190147899	2217	dbSNP
rs569291765	2218	dbSNP
rs1181758865	2223	dbSNP
rs182315587	2230	dbSNP
rs1435461268	2231	dbSNP
rs1029365669	2244	dbSNP
rs1301307557	2251	dbSNP
rs953713407	2252	dbSNP
rs763495738	2253	dbSNP
rs1359785164	2266	dbSNP
rs1167982099	2268	dbSNP
rs548319412	2269	dbSNP
rs1197447884	2271	dbSNP
rs1017601282	2280	dbSNP
rs139356062	2286	dbSNP
rs533895703	2287	dbSNP
rs1476028139	2291	dbSNP
rs1255125463	2297	dbSNP
rs962531935	2302	dbSNP
rs554063545	2304	dbSNP
rs1483974762	2312	dbSNP
rs6099132	2318	dbSNP
rs1169964442	2325	dbSNP
rs543194663	2329	dbSNP
rs972516329	2334	dbSNP
rs1429564193	2336	dbSNP
rs918398852	2337	dbSNP
rs1299658407	2339	dbSNP
rs1227964595	2343	dbSNP
rs1339652334	2344	dbSNP
rs1303347485	2358	dbSNP
rs1310902517	2362	dbSNP
rs577078755	2363	dbSNP
rs185640670	2368	dbSNP
rs917294335	2370	dbSNP
rs948660585	2383	dbSNP
rs1427832954	2384	dbSNP
rs982699108	2386	dbSNP
rs1229561380	2390	dbSNP
rs556711384	2390	dbSNP
rs11475247	2391	dbSNP
rs1457754613	2391	dbSNP
rs398088523	2391	dbSNP
rs1268147902	2393	dbSNP
rs1425220756	2397	dbSNP
rs1257700238	2400	dbSNP
rs938243839	2400	dbSNP
rs1044675711	2401	dbSNP
rs904745558	2404	dbSNP
rs576106012	2406	dbSNP
rs1263484710	2407	dbSNP
rs751930869	2407	dbSNP
rs1490919633	2411	dbSNP
rs144086977	2425	dbSNP
rs1408149930	2426	dbSNP
rs997986630	2427	dbSNP
rs79827607	2433	dbSNP
rs35839613	2435	dbSNP
rs1266797433	2445	dbSNP
rs6014718	2451	dbSNP
rs765936258	2464	dbSNP
rs1371889472	2468	dbSNP
rs753594645	2475	dbSNP
rs1418197237	2476	dbSNP
rs1449238020	2482	dbSNP
rs572088409	2489	dbSNP
rs1157957515	2495	dbSNP
rs1164676883	2498	dbSNP
rs1006485666	2499	dbSNP
rs1016826273	2508	dbSNP
rs1181846564	2508	dbSNP
rs962625738	2509	dbSNP
rs541000259	2516	dbSNP
rs933814716	2517	dbSNP
rs973049467	2519	dbSNP
rs1335229237	2528	dbSNP
rs1267783536	2539	dbSNP
rs188320852	2546	dbSNP
rs754591693	2548	dbSNP
rs1280243792	2550	dbSNP
rs1232538116	2554	dbSNP
rs1329872423	2561	dbSNP
rs180678367	2565	dbSNP
rs778341726	2566	dbSNP
rs960818819	2571	dbSNP
rs533245733	2572	dbSNP
rs369381869	2573	dbSNP
rs752230803	2577	dbSNP
rs1375922253	2584	dbSNP
rs1026379949	2585	dbSNP
rs577173950	2585	dbSNP
rs950844263	2586	dbSNP
rs980073375	2586	dbSNP
rs549756344	2587	dbSNP
rs115572180	2589	dbSNP
rs1361805380	2593	dbSNP
rs1035591614	2597	dbSNP
rs1053779134	2598	dbSNP
rs1277163016	2600	dbSNP
rs1235640047	2607	dbSNP
rs762162643	2626	dbSNP
rs1486215465	2633	dbSNP
rs1207038712	2634	dbSNP
rs1437646772	2635	dbSNP
rs1346652154	2636	dbSNP

- Genes & development, 2011

MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.