miRTarBase - #MIRT532712


—
pre-miRNA Information
pre-miRNA hsa-mir-4532   
Genomic Coordinates chr20: 57895394 - 57895444
Description Homo sapiens miR-4532 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4532
Sequence 6| CCCCGGGGAGCCCGGCG |22
Evidence Experimental
Experiments Illumina
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol SNRPD3   
Synonyms SMD3, Sm-D3
Description small nuclear ribonucleoprotein D3 polypeptide
Transcript NM_004175   
Expression
Putative miRNA Targets on SNRPD3
3'UTR of SNRPD3
(miRNA target sites are highlighted)		 
>SNRPD3|NM_004175|3'UTR
   1 TTTTCTAAGTTGAACAGAACTTTGTCCTTTTTTCTTTCAGGTTATCTGAGTTCATTGGAGTGGGTGCTTGTGCATATATG
  81 CTAGGTATCTTTTGCCATCTTTCTCTTTAGATCAGGGGAAATGTTTAAGCTAAATAAATCTGGGGGGTTTTTTGTTCTGT
 161 TTTGTTTTGTTTTCTTTGAGAAAATAAGGACTTTGTGTTCATTTGAAGTTTGCTTTGGCTAAATTTTGACACCCTGGGGG
 241 ATGTCCTGGGAGAATGCCAGTACTTTGAAATAGCACAGCTATTGATGAGATTTTAAGCTGCTGTTCCTGGCCAGTTGCAG
 321 GTTAAGCCCCAGAAAAGTTCACCTTGGAGAAGCTCCGAGAACACACAGATTGTGTCTCATTCATCTTCAGACACAGGCAC
 401 ATAGTGTGGCACTTTGTTCAGTTAACATTTGTGGAGCTGTCATCAGCTCAGCTTTAACAACACAGGTGACTCTTTCCCTT
 481 GATAAAGTCATAGGTAATTCAGGGGCTGGGTGCGGCGGCTCACGCATGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGC
 561 GGATCACGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATATGGTGAAACCTCGTGTGTACTAAAAATAAAAAAATTAGCC
 641 GGGTGCGGTGGCATGTACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGAAGATTCGCTTGAACCCAGGAGGTGGACA
 721 TTGCAGTGAGCAGAGATCATGCCACTGTACTCCAGCTTGGGTGACAGAGCGAGACTGCACCTCAAAAAAAAAAAAGTAAT
 801 TCAGGGGATCCTAGTGGCCAGCTTCCTTGGCTCGTATACTGGCTACAACAAGTAGTTTTGTGGTGATTTGTGGAAACAGA
 881 TTCTTGGGAGCATATCAGAGCATCTCAGCATTGATTGGCACATCCATAGTTGTTAATGTAGGAAGGGTGACCAGCAGCTC
 961 AGCACAGTGGCTTGCTTCCAGCACTCTGGGAGGCTGAGGTAGAGGATTGTTTGAGAGGAGTTCAAAACCAGCCCGCGAGA
1041 CATAGTGAGACCCTGTCTCTACAAAAAATTCTAAAAATTAACTTGGCATGGTGGTGCACACCTGTAGTCCTCGCTACTAG
1121 GGAGGCTGAGGTGGGAGGATCACTTGAGCCTGGGAGTATGAGGCTGCAGTGAGCTATGACCTTGCCACTGTACTCCAGCC
1201 TGGGCAAAAGAGCAAGACTTTGTCTTTAAAGAAAAATAAGTAGTAGTAAAGAGTATAAGATACACAGGGTGAATAATTGT
1281 GACAAAAACACAGAAACTGGAAAAGCAGCCTGAAAAAATCAAATCACCAAAAAGAGGTCTTGCCAGGTATTCATTATGGT
1361 ATGAGCTACAGCATAAGCCATCAAGAGGAAAACTGATCAATTATTGGCTTTTAGAATATTGCTCATTGAACAGATTATTC
1441 AAGTAATGAAAGAGGAGGGGAAAAAAATCCAGCACATTAGTTAACCTGGCATCAATTAATGAGGTTCTAATAAGCTTTGT
1521 CTTATGATACTACCTGGAGGTTACAGAGCTGGTATTCTGAGGAATAAGCATCAGTGAGTTGGTCAGATACAATAGACGTT
1601 TAAAATAGGGCTTCAGGCCAAACATGGTGCCCCACGCCTATAATGCCAGCACTTTGGGAGGTCGAGGCGGGAGGATCACT
1681 TGAACCTAGGAGTTTGAGACTAGCCTGGGCTGTTAAGCTTTGTTAACCAAGACCGCATCTCTACAAAAAATTGAAAAGTA
1761 GCTGGGCACAGCTGATGCCTGCAGTCCCAGCTATCCTGGAGGTTGAGGCAGGACGACCACATGAGCCCAGGAGATTAAGG
1841 CTGCAGTGAGCTATAATTGCACCACTGCACTCCAGCCTGGATGACAGTGAGACCCTGTCTCTTAAATAAAAAACAAATGA
1921 AAGCAGTGGTTTTCAACATCAACTAAGGATCTTATTAGAAATGAAGACTGCAAGCCGCACACCTGGAGTGGGGCCCAGGA
2001 ATCTGCATTTTAAACAATTCCCTGGTCCCCAGATAAGTAATTCTTAAGTATTCTATCTTAAGTAGACCTAAAGCCGTATT
2081 TTGACCCTGTACTAGTATGTTATTTTAGTATAATCATTACTGAATTCATCATACTTTTACAGTAAACAGTACTTACTTTG
2161 AATAATAACACATTACACTTAATAGTAGTGAACTGCATCCTCGATATCAAAAGCGACTTTTGATGTAGTTCACTCTGGAC
2241 CCGTACAGGAACACCAGCCTTGCAGATTCTCCACGCAATGGAAACTGGCTATAACCCTACCTAGATCTGAAAAGTGAAGG
2321 GGGATCAACCTAAAATATGTAGCTTTGTAAACAGTTTTATATCCTGCATCTTAGGGGGGAAAATCAGTTGACGCAGATTG
2401 AAAACAAGTTGTTCCATAAGGTTTATTATGAAAAACAGTAGCCCTCCTACCCTGCCTTTACCCCACTTTCCTTGCCTCAC
2481 AGTAGTCTGTCCAACTCTTGGCTGATTTGTTTGTATTTACCTCCATGTCTCAATATGAACATGTTTTCATGACTATTCCT
2561 TGATGGTTTTTTGTTTGCTTGTTTTAAGACGGTCTCACTCTTCCCCAGGCGGGAGTGCAATGGCACAATCATGGCTCACT
2641 GCAGCCTCAACCTTCTCGGGCTCAGGTGATTCTCCCACCTCAGCCTCCTGAGTAGCTAGAAATACTGGTGCACACCACCA
2721 TGCCTAGCTAATTTTTGTATTTTTTGTAGAGACAGGGTTTTGCCATGTTGCCCAAGCTGGTCTTGAACTCCGGGGCTCAA
2801 GTGATCTGCCCGCCTCGGCCTGCTGGGATTATAGGTGTGAGCCACTGCACCCGGCCACCATTATCTTTTGAATCCTCTCT
2881 TCCTCCTGCCCACCATGAATTTACTTCCTCTCACCCATCTCCCTGATATTGTAATTCTGGTTAGATCATATTCAGTGTCA
2961 AATTATTAAGATGTGATTAAACTTTTT
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' gcGGCCCGA----GGGGCCCc 5'
            |:|| ||    |:||||| 
Target 5' agCTGGTCTTGAACTCCGGGg 3'
 2775 - 2795 133.00 -24.80
2 
miRNA  3' gcggcCCGAGGGGCCCc 5'
               | | |||:||| 
Target 5' attttGACACCCTGGGg 3'
 223 - 239 128.00 -18.10
3 
miRNA  3' gcggcccGAGGGGCCCc 5'
                 ||:|:|||| 
Target 5' cctcaacCTTCTCGGGc 3'
 2645 - 2661 118.00 -14.30
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSM3842316 49 COSMIC
COSM8284735 49 COSMIC
COSM9302835 54 COSMIC
COSN30113700 138 COSMIC
COSN28859762 148 COSMIC
COSN30130334 148 COSMIC
COSN31555766 149 COSMIC
COSN31541780 163 COSMIC
COSN27904135 201 COSMIC
COSN16227883 338 COSMIC
COSN5989652 540 COSMIC
COSN4974077 613 COSMIC
COSN10028641 627 COSMIC
COSN30334422 885 COSMIC
COSN5989653 1130 COSMIC
COSN5989654 1256 COSMIC
COSN20954087 1763 COSMIC
COSN5454540 2186 COSMIC
COSN19597050 2206 COSMIC
COSN9162721 2209 COSMIC
COSN20675641 2275 COSMIC
COSN15009130 2306 COSMIC
COSN10028642 2649 COSMIC
COSN9162722 2954 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs745375990 1 dbSNP
rs1042654 6 dbSNP
rs769236827 9 dbSNP
rs775146318 13 dbSNP
rs768484185 14 dbSNP
rs1421333189 16 dbSNP
rs183038834 18 dbSNP
rs761870566 31 dbSNP
rs1412418666 33 dbSNP
rs767348858 39 dbSNP
rs750305886 40 dbSNP
rs1213360094 43 dbSNP
rs955728119 47 dbSNP
rs976364391 51 dbSNP
rs1347325595 60 dbSNP
rs1400936941 61 dbSNP
rs1298149414 72 dbSNP
rs940189012 73 dbSNP
rs774868985 74 dbSNP
rs1487942074 76 dbSNP
rs1029547775 77 dbSNP
rs763810550 81 dbSNP
rs550760175 86 dbSNP
rs1037183323 90 dbSNP
rs759697742 96 dbSNP
rs765355854 98 dbSNP
rs1286534241 103 dbSNP
rs917320793 105 dbSNP
rs867672691 106 dbSNP
rs752998013 109 dbSNP
rs188465154 111 dbSNP
rs1336417203 112 dbSNP
rs1215574075 113 dbSNP
rs1295504091 113 dbSNP
rs1260727508 117 dbSNP
rs1234239814 119 dbSNP
rs1044506400 121 dbSNP
rs1268974382 124 dbSNP
rs1433499607 126 dbSNP
rs1345922737 127 dbSNP
rs1322909653 129 dbSNP
rs1188151310 131 dbSNP
rs905822866 142 dbSNP
rs865894165 145 dbSNP
rs1165413005 148 dbSNP
rs985315301 149 dbSNP
rs1188275577 151 dbSNP
rs561047283 158 dbSNP
rs1335640154 181 dbSNP
rs909746609 190 dbSNP
rs566269358 196 dbSNP
rs941197735 209 dbSNP
rs191761698 222 dbSNP
rs918659029 225 dbSNP
rs1227434662 231 dbSNP
rs1293865637 235 dbSNP
rs1216845189 260 dbSNP
rs939354279 263 dbSNP
rs1363192003 275 dbSNP
rs1056442263 285 dbSNP
rs1438747272 287 dbSNP
rs548563175 303 dbSNP
rs1286123811 308 dbSNP
rs1326870670 309 dbSNP
rs1465290608 326 dbSNP
rs916834190 327 dbSNP
rs1229467781 331 dbSNP
rs1410466334 341 dbSNP
rs1018759988 345 dbSNP
rs868508310 348 dbSNP
rs1253077083 356 dbSNP
rs965886265 357 dbSNP
rs948342622 358 dbSNP
rs184005320 365 dbSNP
rs1249982142 373 dbSNP
rs1207019658 375 dbSNP
rs537442662 381 dbSNP
rs1308625994 386 dbSNP
rs1278603354 394 dbSNP
rs1232709770 397 dbSNP
rs1350226498 401 dbSNP
rs999679610 402 dbSNP
rs951791876 403 dbSNP
rs984510482 405 dbSNP
rs1442601405 409 dbSNP
rs757650281 413 dbSNP
rs1053297713 416 dbSNP
rs891517300 420 dbSNP
rs1017121544 428 dbSNP
rs997815266 459 dbSNP
rs1171761644 461 dbSNP
rs1180083533 463 dbSNP
rs1395174846 464 dbSNP
rs549976679 466 dbSNP
rs1252172553 471 dbSNP
rs972974135 472 dbSNP
rs1159642766 473 dbSNP
rs1481189902 473 dbSNP
rs917394205 477 dbSNP
rs1281137876 490 dbSNP
rs546715574 490 dbSNP
rs1239469903 491 dbSNP
rs570996363 499 dbSNP
rs1309486103 502 dbSNP
rs1224512675 503 dbSNP
rs1007253507 507 dbSNP
rs538475934 509 dbSNP
rs553573129 510 dbSNP
rs572112513 514 dbSNP
rs1310787567 516 dbSNP
rs972571058 517 dbSNP
rs565090802 518 dbSNP
rs1297064673 521 dbSNP
rs1451053139 522 dbSNP
rs960740852 524 dbSNP
rs1054484725 525 dbSNP
rs992239012 526 dbSNP
rs796223225 527 dbSNP
rs1417614580 528 dbSNP
rs945921831 531 dbSNP
rs1137754 532 dbSNP
rs916616274 535 dbSNP
rs1301018687 538 dbSNP
rs1258773771 539 dbSNP
rs1137755 540 dbSNP
rs1310764349 554 dbSNP
rs1484957642 557 dbSNP
rs948064954 558 dbSNP
rs1267485217 560 dbSNP
rs1044392481 561 dbSNP
rs1342039153 562 dbSNP
rs1203193245 568 dbSNP
rs925533195 569 dbSNP
rs935511431 571 dbSNP
rs6004187 582 dbSNP
rs1190761371 583 dbSNP
rs554520648 590 dbSNP
rs1386579296 595 dbSNP
rs1288887389 598 dbSNP
rs891550117 599 dbSNP
rs576428078 602 dbSNP
rs1243971567 604 dbSNP
rs997931254 613 dbSNP
rs1431183947 614 dbSNP
rs1476420307 618 dbSNP
rs1418990743 620 dbSNP
rs1193178838 623 dbSNP
rs543827256 624 dbSNP
rs12172173 629 dbSNP
rs1395686241 641 dbSNP
rs889479874 642 dbSNP
rs1006541657 647 dbSNP
rs565410378 648 dbSNP
rs577388446 656 dbSNP
rs1225173442 658 dbSNP
rs1137756 670 dbSNP
rs1328063901 672 dbSNP
rs1371794490 677 dbSNP
rs1430032818 678 dbSNP
rs1368125395 688 dbSNP
rs962631906 695 dbSNP
rs887556284 699 dbSNP
rs994406768 700 dbSNP
rs1014516628 721 dbSNP
rs1025520528 728 dbSNP
rs538213296 742 dbSNP
rs992271600 743 dbSNP
rs547527231 746 dbSNP
rs1453909723 748 dbSNP
rs972921991 751 dbSNP
rs1195790570 756 dbSNP
rs1469033282 758 dbSNP
rs1365183026 766 dbSNP
rs1024522934 771 dbSNP
rs1193820721 772 dbSNP
rs1226765628 774 dbSNP
rs1341417269 776 dbSNP
rs1276872971 780 dbSNP
rs1233436679 784 dbSNP
rs1251869146 784 dbSNP
rs1441186208 784 dbSNP
rs879420221 784 dbSNP
rs980335548 784 dbSNP
rs78631223 786 dbSNP
rs1342914234 788 dbSNP
rs969812484 790 dbSNP
rs927352386 795 dbSNP
rs1221141348 796 dbSNP
rs1390074510 796 dbSNP
rs1491311991 796 dbSNP
rs979428145 799 dbSNP
rs113376986 802 dbSNP
rs913196336 807 dbSNP
rs1393358097 812 dbSNP
rs1211475121 822 dbSNP
rs541506332 834 dbSNP
rs1040306725 835 dbSNP
rs1186548600 845 dbSNP
rs751363080 849 dbSNP
rs1179900709 851 dbSNP
rs1476003276 863 dbSNP
rs1391500989 875 dbSNP
rs901795336 877 dbSNP
rs1250967751 878 dbSNP
rs931787157 884 dbSNP
rs34491727 886 dbSNP
rs923476578 891 dbSNP
rs933478126 893 dbSNP
rs1050826472 899 dbSNP
rs889522165 905 dbSNP
rs369742570 916 dbSNP
rs1347831659 926 dbSNP
rs768904002 927 dbSNP
rs192592859 939 dbSNP
rs1005905155 946 dbSNP
rs868845080 948 dbSNP
rs1435472938 953 dbSNP
rs1013241594 954 dbSNP
rs898150135 957 dbSNP
rs994117441 974 dbSNP
rs1025551757 980 dbSNP
rs1471273313 983 dbSNP
rs1364178558 984 dbSNP
rs896342666 999 dbSNP
rs569419655 1006 dbSNP
rs1034495382 1008 dbSNP
rs1211465753 1010 dbSNP
rs1013400240 1019 dbSNP
rs538165529 1022 dbSNP
rs990199072 1026 dbSNP
rs1281504872 1030 dbSNP
rs969464241 1033 dbSNP
rs1350852735 1034 dbSNP
rs979843895 1035 dbSNP
rs78051568 1036 dbSNP
rs1032384148 1037 dbSNP
rs548913972 1040 dbSNP
rs1295699990 1043 dbSNP
rs1141314 1045 dbSNP
rs1433569226 1052 dbSNP
rs144566747 1054 dbSNP
rs1366531337 1056 dbSNP
rs988381840 1058 dbSNP
rs776481424 1066 dbSNP
rs5760480 1072 dbSNP
rs1310646746 1074 dbSNP
rs1164452187 1079 dbSNP
rs1459713363 1083 dbSNP
rs574670602 1095 dbSNP
rs147425667 1103 dbSNP
rs986236676 1113 dbSNP
rs1475007455 1114 dbSNP
rs909009328 1120 dbSNP
rs910972780 1129 dbSNP
rs941878675 1131 dbSNP
rs1447248030 1136 dbSNP
rs1272210972 1144 dbSNP
rs1036064569 1151 dbSNP
rs1333237172 1156 dbSNP
rs942501302 1159 dbSNP
rs1038519191 1161 dbSNP
rs1361791600 1169 dbSNP
rs1268513959 1175 dbSNP
rs1013187452 1191 dbSNP
rs898188059 1194 dbSNP
rs929608803 1198 dbSNP
rs1047030973 1199 dbSNP
rs570883887 1200 dbSNP
rs769749742 1201 dbSNP
rs904871611 1205 dbSNP
rs777908258 1214 dbSNP
rs1035021913 1218 dbSNP
rs183670576 1219 dbSNP
rs771344963 1219 dbSNP
rs1165131144 1220 dbSNP
rs1409331033 1228 dbSNP
rs1486153217 1231 dbSNP
rs1180838104 1238 dbSNP
rs957517785 1239 dbSNP
rs1425194569 1248 dbSNP
rs1475480402 1253 dbSNP
rs879843804 1256 dbSNP
rs1013432854 1260 dbSNP
rs1411719939 1261 dbSNP
rs1020360478 1265 dbSNP
rs1023428851 1266 dbSNP
rs1346367212 1268 dbSNP
rs1216823574 1275 dbSNP
rs1447867933 1279 dbSNP
rs529432676 1282 dbSNP
rs534169396 1284 dbSNP
rs1373416369 1286 dbSNP
rs953507419 1290 dbSNP
rs774906133 1319 dbSNP
rs1441278943 1320 dbSNP
rs762515246 1321 dbSNP
rs1264510092 1325 dbSNP
rs1288013112 1338 dbSNP
rs1330896184 1341 dbSNP
rs547048689 1345 dbSNP
rs770956903 1354 dbSNP
rs186828795 1357 dbSNP
rs909156028 1374 dbSNP
rs1455331810 1375 dbSNP
rs114303641 1385 dbSNP
rs554887851 1405 dbSNP
rs918995419 1411 dbSNP
rs1207257769 1414 dbSNP
rs986267910 1415 dbSNP
rs1317463509 1433 dbSNP
rs1046591109 1457 dbSNP
rs904821215 1461 dbSNP
rs139729890 1462 dbSNP
rs963865640 1466 dbSNP
rs1302298035 1467 dbSNP
rs537468379 1469 dbSNP
rs893413759 1470 dbSNP
rs1370987094 1474 dbSNP
rs973872044 1476 dbSNP
rs1410366424 1486 dbSNP
rs1374730520 1493 dbSNP
rs559011205 1496 dbSNP
rs919645403 1498 dbSNP
rs11912571 1507 dbSNP
rs903369697 1513 dbSNP
rs1479125787 1515 dbSNP
rs1416879641 1536 dbSNP
rs5996718 1540 dbSNP
rs5996719 1543 dbSNP
rs949320319 1545 dbSNP
rs1209320255 1546 dbSNP
rs1486735835 1548 dbSNP
rs1256654704 1549 dbSNP
rs763865859 1574 dbSNP
rs1215348840 1592 dbSNP
rs986576277 1593 dbSNP
rs1016118963 1594 dbSNP
rs1045378924 1598 dbSNP
rs575020922 1599 dbSNP
rs971970797 1601 dbSNP
rs553968351 1606 dbSNP
rs949248213 1616 dbSNP
rs1287706602 1619 dbSNP
rs542044534 1625 dbSNP
rs1001089781 1636 dbSNP
rs368627433 1649 dbSNP
rs1458134749 1655 dbSNP
rs892523293 1659 dbSNP
rs1009534134 1661 dbSNP
rs937671495 1664 dbSNP
rs1186503331 1665 dbSNP
rs1426018893 1666 dbSNP
rs1053891564 1669 dbSNP
rs1030252295 1670 dbSNP
rs1485029639 1672 dbSNP
rs954699071 1677 dbSNP
rs947594866 1678 dbSNP
rs1270975597 1680 dbSNP
rs1235064718 1687 dbSNP
rs751203258 1689 dbSNP
rs1294256062 1701 dbSNP
rs1380073285 1701 dbSNP
rs1018253392 1707 dbSNP
rs1320894990 1710 dbSNP
rs963595481 1716 dbSNP
rs746135768 1722 dbSNP
rs1394227309 1732 dbSNP
rs80036676 1735 dbSNP
rs998128073 1736 dbSNP
rs1426883067 1738 dbSNP
rs1249964210 1745 dbSNP
rs1189471913 1750 dbSNP
rs1468151710 1751 dbSNP
rs1250938686 1756 dbSNP
rs1030413839 1770 dbSNP
rs1189807967 1771 dbSNP
rs919693537 1777 dbSNP
rs951071378 1784 dbSNP
rs1225150886 1788 dbSNP
rs1308812358 1794 dbSNP
rs1007548494 1797 dbSNP
rs1233119947 1799 dbSNP
rs1368287322 1800 dbSNP
rs1168056483 1807 dbSNP
rs145050010 1809 dbSNP
rs772426609 1814 dbSNP
rs917624118 1815 dbSNP
rs144868220 1823 dbSNP
rs564549055 1826 dbSNP
rs1460864502 1842 dbSNP
rs1195172559 1844 dbSNP
rs531934532 1846 dbSNP
rs1169255936 1849 dbSNP
rs1045013525 1851 dbSNP
rs1330720526 1853 dbSNP
rs540061118 1854 dbSNP
rs1026220827 1861 dbSNP
rs970582163 1864 dbSNP
rs1201237587 1865 dbSNP
rs926509543 1868 dbSNP
rs1249544559 1871 dbSNP
rs936532125 1877 dbSNP
rs982375209 1885 dbSNP
rs148640368 1886 dbSNP
rs1296266872 1896 dbSNP
rs1209467886 1898 dbSNP
rs1345092515 1911 dbSNP
rs1276291293 1915 dbSNP
rs376044332 1924 dbSNP
rs1332053463 1926 dbSNP
rs1306652728 1932 dbSNP
rs937729053 1937 dbSNP
rs1273318634 1943 dbSNP
rs775955506 1955 dbSNP
rs1009648880 1963 dbSNP
rs1309142692 1964 dbSNP
rs529932687 1966 dbSNP
rs1373702739 1967 dbSNP
rs989247742 1972 dbSNP
rs750784705 1983 dbSNP
rs548057160 1995 dbSNP
rs1363021237 2008 dbSNP
rs1179351238 2012 dbSNP
rs1473545445 2016 dbSNP
rs142108186 2020 dbSNP
rs537356630 2021 dbSNP
rs1188444507 2026 dbSNP
rs1007948126 2030 dbSNP
rs1451464277 2033 dbSNP
rs1168540524 2041 dbSNP
rs1390375573 2053 dbSNP
rs756625426 2056 dbSNP
rs558848384 2058 dbSNP
rs151311682 2063 dbSNP
rs780578404 2068 dbSNP
rs1414690599 2071 dbSNP
rs1403802681 2073 dbSNP
rs140538486 2077 dbSNP
rs1336180028 2088 dbSNP
rs577278916 2093 dbSNP
rs1384467991 2103 dbSNP
rs1157024533 2121 dbSNP
rs1008035027 2135 dbSNP
rs574819006 2147 dbSNP
rs1187151341 2150 dbSNP
rs1474146387 2153 dbSNP
rs1362901265 2155 dbSNP
rs899162408 2157 dbSNP
rs762286 2163 dbSNP
rs1259277732 2173 dbSNP
rs982557301 2176 dbSNP
rs1270253678 2180 dbSNP
rs1355229485 2181 dbSNP
rs1269104789 2183 dbSNP
rs868386008 2203 dbSNP
rs970431472 2204 dbSNP
rs980821517 2215 dbSNP
rs557288549 2216 dbSNP
rs936549119 2218 dbSNP
rs575392761 2235 dbSNP
rs1033906592 2236 dbSNP
rs1163890294 2237 dbSNP
rs546092349 2238 dbSNP
rs913763970 2241 dbSNP
rs192822536 2243 dbSNP
rs959236899 2244 dbSNP
rs945201106 2253 dbSNP
rs1051812421 2255 dbSNP
rs890518294 2263 dbSNP
rs1466636802 2275 dbSNP
rs184964201 2276 dbSNP
rs540652780 2278 dbSNP
rs374712738 2279 dbSNP
rs1039413686 2290 dbSNP
rs766751532 2292 dbSNP
rs995537080 2296 dbSNP
rs1450214943 2298 dbSNP
rs1165168627 2305 dbSNP
rs566504695 2309 dbSNP
rs1229390546 2311 dbSNP
rs886635808 2315 dbSNP
rs924876450 2323 dbSNP
rs1461800487 2326 dbSNP
rs111767307 2339 dbSNP
rs1024747135 2347 dbSNP
rs1366140818 2348 dbSNP
rs1386430630 2349 dbSNP
rs1434075899 2353 dbSNP
rs1052043049 2355 dbSNP
rs1318416152 2360 dbSNP
rs1409239246 2367 dbSNP
rs1387790501 2373 dbSNP
rs910674746 2373 dbSNP
rs943549275 2374 dbSNP
rs970843608 2375 dbSNP
rs1339331203 2380 dbSNP
rs1037746401 2381 dbSNP
rs980469465 2383 dbSNP
rs75797335 2384 dbSNP
rs749966538 2386 dbSNP
rs1222969454 2387 dbSNP
rs1437715893 2387 dbSNP
rs569872687 2393 dbSNP
rs762449230 2394 dbSNP
rs1342923234 2395 dbSNP
rs117182084 2399 dbSNP
rs552548692 2404 dbSNP
rs913793763 2406 dbSNP
rs1303031480 2410 dbSNP
rs1217672556 2416 dbSNP
rs1343633769 2417 dbSNP
rs1441433239 2436 dbSNP
rs906553260 2438 dbSNP
rs1309756741 2444 dbSNP
rs945232103 2447 dbSNP
rs1173590707 2451 dbSNP
rs1206195253 2461 dbSNP
rs1434486680 2470 dbSNP
rs1427729747 2485 dbSNP
rs570747038 2514 dbSNP
rs1192087015 2525 dbSNP
rs1255583714 2527 dbSNP
rs1469926413 2528 dbSNP
rs544493630 2539 dbSNP
rs9830 2542 dbSNP
rs568408429 2550 dbSNP
rs1010785162 2552 dbSNP
rs1039115307 2554 dbSNP
rs1022035902 2556 dbSNP
rs1328687533 2557 dbSNP
rs868331142 2567 dbSNP
rs1348366067 2574 dbSNP
rs1472377778 2574 dbSNP
rs1158162977 2577 dbSNP
rs1409409813 2578 dbSNP
rs1455313525 2579 dbSNP
rs1159030639 2581 dbSNP
rs1401387896 2582 dbSNP
rs1412300110 2591 dbSNP
rs190204065 2592 dbSNP
rs1300501184 2597 dbSNP
rs867164471 2601 dbSNP
rs930647394 2602 dbSNP
rs1408780326 2605 dbSNP
rs1359429736 2606 dbSNP
rs1048021188 2610 dbSNP
rs1337851992 2611 dbSNP
rs888052645 2612 dbSNP
rs748825478 2615 dbSNP
rs1473166028 2619 dbSNP
rs1255593609 2620 dbSNP
rs556988991 2621 dbSNP
rs754817871 2625 dbSNP
rs1255963486 2626 dbSNP
rs575480450 2629 dbSNP
rs773990753 2630 dbSNP
rs1343484933 2631 dbSNP
rs1326887097 2635 dbSNP
rs922239546 2636 dbSNP
rs906021497 2638 dbSNP
rs955072517 2640 dbSNP
rs1334005320 2642 dbSNP
rs545977899 2651 dbSNP
rs1002399087 2658 dbSNP
rs1180243249 2659 dbSNP
rs910842642 2665 dbSNP
rs1432366892 2671 dbSNP
rs1386912712 2678 dbSNP
rs1033423815 2694 dbSNP
rs1161775017 2702 dbSNP
rs1458252337 2712 dbSNP
rs1368447903 2714 dbSNP
rs957957412 2715 dbSNP
rs1037860198 2716 dbSNP
rs1414615097 2717 dbSNP
rs62231180 2722 dbSNP
rs1182225027 2729 dbSNP
rs1377068819 2750 dbSNP
rs1020831494 2752 dbSNP
rs966566501 2755 dbSNP
rs1249698779 2757 dbSNP
rs987341760 2758 dbSNP
rs1141318 2766 dbSNP
rs911754242 2767 dbSNP
rs1488015989 2771 dbSNP
rs964558659 2772 dbSNP
rs1071684 2776 dbSNP
rs1428729088 2780 dbSNP
rs920661007 2784 dbSNP
rs767174390 2786 dbSNP
rs1225762587 2788 dbSNP
rs1366854550 2789 dbSNP
rs573177918 2790 dbSNP
rs930647816 2792 dbSNP
rs1047719862 2793 dbSNP
rs939401331 2794 dbSNP
rs1447645868 2796 dbSNP
rs1198336441 2800 dbSNP
rs1392402263 2812 dbSNP
rs752644998 2817 dbSNP
rs773488365 2818 dbSNP
rs112606759 2819 dbSNP
rs1237054448 2823 dbSNP
rs1046009776 2824 dbSNP
rs1264931269 2831 dbSNP
rs895088416 2833 dbSNP
rs906047184 2836 dbSNP
rs1010731220 2837 dbSNP
rs1273312443 2838 dbSNP
rs1022109388 2847 dbSNP
rs1001684815 2849 dbSNP
rs1297965324 2853 dbSNP
rs761058844 2853 dbSNP
rs1341489162 2854 dbSNP
rs370350249 2860 dbSNP
rs999238369 2860 dbSNP
rs757347553 2861 dbSNP
rs1253346366 2865 dbSNP
rs1389070421 2870 dbSNP
rs1481080041 2874 dbSNP
rs1307923455 2876 dbSNP
rs1427977110 2878 dbSNP
rs766817347 2882 dbSNP
rs1169476676 2886 dbSNP
rs1375751361 2892 dbSNP
rs113359726 2914 dbSNP
rs76039210 2930 dbSNP
rs1010538276 2932 dbSNP
rs559100025 2936 dbSNP
rs966347335 2937 dbSNP
rs1179923988 2942 dbSNP
rs1266341408 2943 dbSNP
rs1008793654 2945 dbSNP
rs1018850159 2946 dbSNP
rs754284221 2954 dbSNP
rs1452510449 2965 dbSNP
rs1195369433 2967 dbSNP
rs1395586600 2969 dbSNP
rs964915631 2972 dbSNP
rs1448391645 2982 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 6634.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' gcggcccgagGGGCCCc 5'
                    |||||| 
Target 5' ----------CCCGGGa 3'
 		1 - 7
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000215829.3 | 3UTR | CCCGGGAGGUGGAGCCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
119 hsa-miR-4532 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT451366 UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2 2
MIRT451448 ZNF556 zinc finger protein 556 2 4
MIRT458550 CYP2B6 cytochrome P450 family 2 subfamily B member 6 2 2
MIRT460274 SLC26A2 solute carrier family 26 member 2 2 2
MIRT460365 TXNDC16 thioredoxin domain containing 16 2 4
MIRT460539 TM4SF5 transmembrane 4 L six family member 5 2 2
MIRT463626 YY1 YY1 transcription factor 2 2
MIRT468524 SERTAD2 SERTA domain containing 2 2 4
MIRT469966 PTPRF protein tyrosine phosphatase, receptor type F 2 8
MIRT470076 PTGES2 prostaglandin E synthase 2 2 2
MIRT474926 KCTD20 potassium channel tetramerization domain containing 20 2 2
MIRT479976 CARD10 caspase recruitment domain family member 10 2 2
MIRT485533 GPRIN1 G protein regulated inducer of neurite outgrowth 1 2 2
MIRT485939 ECSIT ECSIT signalling integrator 2 4
MIRT486421 RXRA retinoid X receptor alpha 2 2
MIRT487665 HPCAL1 hippocalcin like 1 2 4
MIRT488113 POU3F1 POU class 3 homeobox 1 2 4
MIRT490648 FEM1A fem-1 homolog A 2 2
MIRT491313 LRFN1 leucine rich repeat and fibronectin type III domain containing 1 2 2
MIRT491345 CPNE5 copine 5 2 2
MIRT492688 PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2 2
MIRT496879 AHCYL2 adenosylhomocysteinase like 2 2 2
MIRT499243 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT508211 SLC35E1 solute carrier family 35 member E1 2 2
MIRT532712 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT540807 SLC35F5 solute carrier family 35 member F5 2 2
MIRT563529 TAF8 TATA-box binding protein associated factor 8 2 2
MIRT607723 LIMS1 LIM zinc finger domain containing 1 2 2
MIRT608089 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT618519 SELPLG selectin P ligand 2 2
MIRT624702 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT624769 AKR1D1 aldo-keto reductase family 1 member D1 2 2
MIRT629974 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT631355 ZFP82 ZFP82 zinc finger protein 2 2
MIRT631425 CDNF cerebral dopamine neurotrophic factor 2 2
MIRT631664 NDUFV3 NADH:ubiquinone oxidoreductase subunit V3 2 2
MIRT631734 SF3B1 splicing factor 3b subunit 1 2 2
MIRT632333 TCEANC2 transcription elongation factor A N-terminal and central domain containing 2 2 2
MIRT632418 SLC30A5 solute carrier family 30 member 5 2 2
MIRT632530 PSMB2 proteasome subunit beta 2 2 2
MIRT633263 LDLR low density lipoprotein receptor 2 2
MIRT634326 SLC43A2 solute carrier family 43 member 2 2 2
MIRT634752 CRCP CGRP receptor component 2 2
MIRT635411 KIAA1614 KIAA1614 2 2
MIRT636280 RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase 2 2
MIRT636290 RAD51L3-RFFL RAD51L3-RFFL readthrough 2 2
MIRT641737 TXNL1 thioredoxin like 1 2 2
MIRT643527 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643554 C11orf70 chromosome 11 open reading frame 70 2 2
MIRT647026 NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 2 2
MIRT647297 RBM43 RNA binding motif protein 43 2 2
MIRT648123 SEMA3E semaphorin 3E 2 4
MIRT648610 TPCN2 two pore segment channel 2 2 2
MIRT648716 IL10RB interleukin 10 receptor subunit beta 2 2
MIRT649424 CDC14B cell division cycle 14B 2 2
MIRT650028 DSG3 desmoglein 3 2 2
MIRT650280 TAS2R5 taste 2 receptor member 5 2 2
MIRT654238 RNF115 ring finger protein 115 2 2
MIRT657031 KCNJ6 potassium voltage-gated channel subfamily J member 6 2 2
MIRT658406 FAM212B family with sequence similarity 212 member B 2 2
MIRT661079 FFAR2 free fatty acid receptor 2 2 2
MIRT661528 NWD1 NACHT and WD repeat domain containing 1 2 2
MIRT661875 PDLIM5 PDZ and LIM domain 5 2 2
MIRT662099 ZNF419 zinc finger protein 419 2 2
MIRT663637 HM13 histocompatibility minor 13 2 2
MIRT663702 ABHD17B abhydrolase domain containing 17B 2 2
MIRT663844 TRIM72 tripartite motif containing 72 2 2
MIRT664768 MESDC2 mesoderm development LRP chaperone 2 2
MIRT665480 VSTM4 V-set and transmembrane domain containing 4 2 2
MIRT666532 RNF157 ring finger protein 157 2 2
MIRT668106 GK5 glycerol kinase 5 (putative) 2 2
MIRT669741 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 2
MIRT671009 MOB4 MOB family member 4, phocein 2 2
MIRT671582 SPIRE2 spire type actin nucleation factor 2 2 2
MIRT673260 INO80 INO80 complex subunit 2 2
MIRT673532 ADRBK2 G protein-coupled receptor kinase 3 2 2
MIRT674713 FAM73A mitoguardin 1 2 2
MIRT675204 ZNF554 zinc finger protein 554 2 2
MIRT676487 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT676704 GXYLT2 glucoside xylosyltransferase 2 2 2
MIRT676850 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT676854 RAB3B RAB3B, member RAS oncogene family 2 2
MIRT676914 PHLDA3 pleckstrin homology like domain family A member 3 2 2
MIRT676999 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT677187 PDE12 phosphodiesterase 12 2 2
MIRT677472 SLC7A11 solute carrier family 7 member 11 2 2
MIRT677561 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677778 FKTN fukutin 2 2
MIRT677895 DCP1A decapping mRNA 1A 2 2
MIRT677995 GATC glutamyl-tRNA amidotransferase subunit C 2 2
MIRT678238 HMGB1 high mobility group box 1 2 4
MIRT678312 MCM8 minichromosome maintenance 8 homologous recombination repair factor 2 2
MIRT678436 PDE4C phosphodiesterase 4C 2 2
MIRT678479 RNF222 ring finger protein 222 2 2
MIRT678590 ZNF91 zinc finger protein 91 2 2
MIRT678862 SLC7A14 solute carrier family 7 member 14 2 2
MIRT679240 LRP10 LDL receptor related protein 10 2 2
MIRT679387 WDR92 WD repeat domain 92 2 2
MIRT679500 ZNF106 zinc finger protein 106 2 2
MIRT679580 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679826 TMEM106B transmembrane protein 106B 2 2
MIRT679859 ZFP30 ZFP30 zinc finger protein 2 2
MIRT680472 C3 complement C3 2 2
MIRT683698 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT684267 PRPF4 pre-mRNA processing factor 4 2 2
MIRT689404 ZNF573 zinc finger protein 573 2 2
MIRT694756 ZNF843 zinc finger protein 843 2 2
MIRT695955 FANCM Fanconi anemia complementation group M 2 2
MIRT696365 EIF2S3 eukaryotic translation initiation factor 2 subunit gamma 2 2
MIRT700681 PPAP2B phospholipid phosphatase 3 2 2
MIRT701214 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT702195 LRRC58 leucine rich repeat containing 58 2 2
MIRT706799 RAI1 retinoic acid induced 1 2 2
MIRT711086 NEUROD2 neuronal differentiation 2 2 2
MIRT715997 RGS12 regulator of G protein signaling 12 2 2
MIRT716399 SEPT5 septin 5 2 2
MIRT718442 RAB11B RAB11B, member RAS oncogene family 2 2
MIRT722159 ARHGAP40 Rho GTPase activating protein 40 2 2
MIRT724960 PTK6 protein tyrosine kinase 6 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4532 Fluorouracil 3385 NSC19893 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant High Pancreatic Cancer cell line (PANC-1)
hsa-miR-4532 Platinum 23939 sensitive High Ovarian Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Gallbladder Cancer cell line (GBC-SD, NOZ)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Dabrafenib 44462760 NSC764134 approved resistant High Melanoma cell line (A375, IGR37, 501Mel)
hsa-miR-4532 Paclitaxel 36314 NSC125973 approved resistant High Non-Small Cell Lung Cancer cell line (A549)
hsa-miR-4532 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Tamoxifen 2733525 NSC180973 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-4532 Oxaliplatin 6857599 NSC266046 approved sensitive High Colorectal Cancer tissue
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-mir-4532 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (BxPC3)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (CAL-27) (mitochondrial RNA)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved sensitive cell line
hsa-miR-4532 Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-4532 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM36)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-4532 Doxorubicin 31703 NSC123127 approved resistant cell line (BAS)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-4532 Neoadjuvant chemotherapy sensitive tissue (breast cancer)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-4532 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)
hsa-miR-4532 Cisplatin 5460033 NSC119875 approved resistant cell line (OVSAHO)

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