miRTarBase - #MIRT533705


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pre-miRNA Information
pre-miRNA hsa-mir-1208   
Genomic Coordinates chr8: 128150116 - 128150188
Synonyms MIRN1208, hsa-mir-1208, MIR1208
Description Homo sapiens miR-1208 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1208
Sequence 12| UCACUGUUCAGACAGGCGGA |31
Evidence Experimental
Experiments Northern
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs756433811 2 dbSNP
rs780440181 3 dbSNP
rs1380328961 4 dbSNP
rs747737307 8 dbSNP
rs771811651 10 dbSNP
rs1350004170 13 dbSNP
rs375652780 17 dbSNP
rs552306924 18 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol TMEM67   
Synonyms JBTS6, MECKELIN, MKS3, NPHP11, TNEM67
Description transmembrane protein 67
Transcript NM_001142301   
Other Transcripts NM_153704   
Expression
Putative miRNA Targets on TMEM67
3'UTR of TMEM67
(miRNA target sites are highlighted)		 
>TMEM67|NM_001142301|3'UTR
   1 CTTCCTGAATAAATAACTTAAAGACTCAGTATAATCATGGCCAAAAAAAAGTCATGATATCAGGTTAGTTTGCCATATTT
  81 TTTAAAACTTATAATGCAGACTATTCTGTTTTTGTTTTTTATTTGCAGAAAGATTTATTTTTATAACTTGGGAATATATA
 161 ACCTGATATAATAGAAAATACTGTTTTCCCATTGTGTGTAGTATTTAATGCAGTAAATAATAAATTAATACTGACAGTGA
 241 GGCCAAAAAAAATCTAAATGTTGCTTTCAGCATAATACTTTTTAATGCTAATTAAAACAGTCCCCATCATTTGTCTCTGT
 321 AGATTATTTTATAAACTGAGAGCTGCCTGAATCTTCTCACATTGACAAAGTAATTTGATTCCAAGTTTAAGACTAGTTTT
 401 CAGTTTGATATTTTCATGTTTTGTGTGCTTATGGTTAAATAAATGTTGAAAGATATTTTCAAGTTTACTTAGAAATTTTA
 481 AATTGTATTATTGCTGATTCAATTTGCATCATTCTAATTGCTCATCCTCTTTGGCAGTGGATTAATTCACTGTTGGGTTA
 561 ATATGCATCTCATGAAATGATATCTTTTCATTCCTTTGTATACCTGTATTAGGTCAGTATACGCTTTCCATGAAATATAT
 641 TTGCATTTCTAATATAGTTTACATTTATTAAGTTATAACGTATGACATTTTTCCCAATATCATTTTTTATACATTTTAAT
 721 TACTTAATGTTTTAAGAGTTCTCTTCCAGAGTTTTGCTTTTCAATTACGTTTAAAGACTGTAAATAACAAACAGTAAGGC
 801 TGGGCGCTGTGGCTTACGCCTGTAATCCCAGCACTTTGGAAGGCCAAGGCACGTGGATCACTTTAGGTCAGGAGTTCAAG
 881 AACAGCCTGGCCAACATGGAAAACCCCATCTCTACAAAAAATACAAAAATTAGTTGGATGTGGTGGCCTGTAATCCCAGC
 961 TATTTGGGAGGCTGAGGCATGAGAATAGCTTGAAACCAGGAGGTGGAGGCTGTAGTGAGCCAGATAGCACCACTGCACTC
1041 CAGCCAGGATGACAGAGCAAGACCCTGTCTCAGAAAAAACAAAAACAAAACACTGTAAATGTATCATGTTTCTCACTGCT
1121 TTCTATGTTAATGCTGTGTAAATACTTAAAATGGAATACTGTATAAATATTATTTATATTTTCTCAGATGAAAATATATA
1201 CTAAAACATTTGGTATTTCTGTTTTCTGTTTCATTAATGTATATCTGATGGAGTACCATTTAGGAATATAACATTATTGG
1281 GGCAGAGGTCCCAGCCATTGCCAAAGTTGAATCTTTTACATTTCCCTGAATCTTGAGGATGACTGAAAAGGAAGTCTTTG
1361 AAACTGCAGTTTCTGAAGGATCACAGTACAGGAATGCCTTTATAAAAGCTGCAGAGATAAATACATGTACTTATATGGCA
1441 TGGATATTTAAAACCACTCACTCAGAAGCATATGAAAGAAATTCAACCATCATTCAACATAGAAGAAGTTAATTTTAGTG
1521 CAAAAGTTTTTAAGTATTAAATTTCACAATAAAGGATCAATTGGCTTACTTGCTGATAAATTAAAACAGAAAACATTTAA
1601 AATCATTCTAAATTTTGTATGATATTTTTATTTTGGCTAGGTGCATAAAAATGTGTTCAGATTTTCAAAAAAAAAAAAAA
1681 AAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agGCGGACAGACUUGUCAcu 5'
            :||:  |:  ||||||  
Target 5' aaTGCTAATTAAAACAGTcc 3'
 284 - 303 126.00 -6.20
2 
miRNA  3' aggcggacaGACUUGUCACu 5'
                   || :|||||| 
Target 5' aaattaataCT-GACAGTGa 3'
 222 - 240 126.00 -12.70
3 
miRNA  3' aggcGGACAGACUUGUCACu 5'
              ||| |:| ::||||| 
Target 5' tcatCCTCTTT-GGCAGTGg 3'
 522 - 540 123.00 -14.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
262739 20 ClinVar
914980 26 ClinVar
363930 180 ClinVar
363931 219 ClinVar
913024 280 ClinVar
363932 301 ClinVar
913394 513 ClinVar
913395 581 ClinVar
914507 691 ClinVar
914508 762 ClinVar
914509 823 ClinVar
363933 853 ClinVar
363934 854 ClinVar
363935 942 ClinVar
363936 943 ClinVar
912309 1100 ClinVar
913429 1425 ClinVar
363937 1435 ClinVar
363938 1654 ClinVar
COSN31496143 23 COSMIC
COSN31502984 28 COSMIC
COSN30502036 41 COSMIC
COSN30102566 42 COSMIC
COSN18733116 51 COSMIC
COSN30557419 51 COSMIC
COSN30482664 66 COSMIC
COSN21382894 70 COSMIC
COSN23792390 74 COSMIC
COSN31546690 113 COSMIC
COSN28212046 116 COSMIC
COSN20974506 575 COSMIC
COSN2299457 585 COSMIC
COSN17075953 623 COSMIC
COSN17746295 772 COSMIC
COSN26526567 844 COSMIC
COSN28357271 883 COSMIC
COSN9688748 1238 COSMIC
COSN32005999 1378 COSMIC
COSN5116729 1583 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1465302709 1 dbSNP
rs750254911 6 dbSNP
rs1298616157 8 dbSNP
rs1408146548 8 dbSNP
rs369159461 10 dbSNP
rs1319265620 15 dbSNP
rs780146264 18 dbSNP
rs55850117 20 dbSNP
rs1425056120 31 dbSNP
rs1299723136 32 dbSNP
rs368465995 33 dbSNP
rs1224440561 34 dbSNP
rs1265562236 35 dbSNP
rs780845308 37 dbSNP
rs747794606 39 dbSNP
rs755765642 41 dbSNP
rs769405960 43 dbSNP
rs775180320 43 dbSNP
rs540908817 44 dbSNP
rs1423844540 47 dbSNP
rs748833933 49 dbSNP
rs1446762337 51 dbSNP
rs768370423 51 dbSNP
rs746273119 53 dbSNP
rs772352774 58 dbSNP
rs559891501 60 dbSNP
rs747512381 65 dbSNP
rs776754092 71 dbSNP
rs1345263572 72 dbSNP
rs1432203515 75 dbSNP
rs767218402 76 dbSNP
rs1366405658 91 dbSNP
rs528635378 92 dbSNP
rs904058031 93 dbSNP
rs541946716 95 dbSNP
rs951492488 97 dbSNP
rs1017725202 101 dbSNP
rs1228315935 103 dbSNP
rs762856901 106 dbSNP
rs562339925 107 dbSNP
rs751612440 110 dbSNP
rs754934599 112 dbSNP
rs981221232 116 dbSNP
rs1035461725 122 dbSNP
rs965167888 125 dbSNP
rs1204613220 131 dbSNP
rs1387289929 133 dbSNP
rs1323341388 134 dbSNP
rs1466703082 138 dbSNP
rs1400638147 140 dbSNP
rs958541973 144 dbSNP
rs1475329745 145 dbSNP
rs991384916 159 dbSNP
rs997489765 160 dbSNP
rs1233657634 163 dbSNP
rs1030355767 166 dbSNP
rs1481767789 169 dbSNP
rs914515136 170 dbSNP
rs947066662 173 dbSNP
rs530988214 174 dbSNP
rs886063174 180 dbSNP
rs1259025775 181 dbSNP
rs1195451275 184 dbSNP
rs977521547 198 dbSNP
rs1276416970 199 dbSNP
rs955246274 201 dbSNP
rs377764263 211 dbSNP
rs886063175 219 dbSNP
rs1301131466 221 dbSNP
rs1448422847 226 dbSNP
rs1400383361 230 dbSNP
rs1327535404 233 dbSNP
rs1403854353 236 dbSNP
rs1453596978 236 dbSNP
rs1194119434 243 dbSNP
rs766748624 250 dbSNP
rs908358361 257 dbSNP
rs933034808 260 dbSNP
rs1051524128 261 dbSNP
rs1442017880 270 dbSNP
rs974220929 274 dbSNP
rs1427252952 276 dbSNP
rs1181114377 278 dbSNP
rs752060945 280 dbSNP
rs1280956994 290 dbSNP
rs937761623 298 dbSNP
rs886063176 301 dbSNP
rs34809974 302 dbSNP
rs538922003 303 dbSNP
rs1056110265 318 dbSNP
rs558577799 318 dbSNP
rs1377490473 319 dbSNP
rs1291453873 337 dbSNP
rs1367273993 343 dbSNP
rs1442109664 363 dbSNP
rs1278477492 399 dbSNP
rs1439357040 404 dbSNP
rs755679387 408 dbSNP
rs1306267813 427 dbSNP
rs1363723636 434 dbSNP
rs1334391097 446 dbSNP
rs1415858465 453 dbSNP
rs572366116 463 dbSNP
rs942864958 467 dbSNP
rs112233974 471 dbSNP
rs1042659321 475 dbSNP
rs904023365 483 dbSNP
rs1158105578 486 dbSNP
rs936820979 488 dbSNP
rs1273847986 492 dbSNP
rs1039613455 496 dbSNP
rs900563548 497 dbSNP
rs1309364324 507 dbSNP
rs1485428137 509 dbSNP
rs570774838 513 dbSNP
rs1255166584 536 dbSNP
rs998024934 540 dbSNP
rs1218470646 541 dbSNP
rs183220842 542 dbSNP
rs1265101074 552 dbSNP
rs1221637070 557 dbSNP
rs1357848559 568 dbSNP
rs551707990 573 dbSNP
rs755440857 575 dbSNP
rs995505639 581 dbSNP
rs1025621708 583 dbSNP
rs887126629 584 dbSNP
rs565331655 585 dbSNP
rs1035742251 593 dbSNP
rs534751646 599 dbSNP
rs1318230554 601 dbSNP
rs958565827 603 dbSNP
rs1416058722 604 dbSNP
rs554347125 606 dbSNP
rs568268659 608 dbSNP
rs959124492 609 dbSNP
rs1419545880 613 dbSNP
rs1429787336 620 dbSNP
rs991897515 621 dbSNP
rs536811866 623 dbSNP
rs969064642 624 dbSNP
rs752705934 632 dbSNP
rs1171018008 633 dbSNP
rs763884998 654 dbSNP
rs1328399557 656 dbSNP
rs1387057511 663 dbSNP
rs1232106125 668 dbSNP
rs1434965482 671 dbSNP
rs924245205 677 dbSNP
rs35321711 680 dbSNP
rs756327958 680 dbSNP
rs557304435 681 dbSNP
rs987178996 683 dbSNP
rs1363085944 690 dbSNP
rs535033320 691 dbSNP
rs1429254271 693 dbSNP
rs1352084874 701 dbSNP
rs942873889 702 dbSNP
rs1312275522 710 dbSNP
rs1326712684 720 dbSNP
rs749545941 720 dbSNP
rs1335802299 726 dbSNP
rs1460967832 738 dbSNP
rs546117654 739 dbSNP
rs1039176924 756 dbSNP
rs553442637 762 dbSNP
rs1429274367 769 dbSNP
rs188098909 770 dbSNP
rs1274772056 778 dbSNP
rs898727742 780 dbSNP
rs933403832 796 dbSNP
rs758228542 797 dbSNP
rs1253510153 799 dbSNP
rs542334986 803 dbSNP
rs557700820 805 dbSNP
rs575810585 806 dbSNP
rs779719406 807 dbSNP
rs931531877 818 dbSNP
rs544358629 819 dbSNP
rs1047313888 821 dbSNP
rs1295335321 823 dbSNP
rs1016273715 827 dbSNP
rs564441988 830 dbSNP
rs1486557578 834 dbSNP
rs898386209 837 dbSNP
rs1440350987 850 dbSNP
rs1033503981 851 dbSNP
rs114214029 853 dbSNP
rs34080297 853 dbSNP
rs191740525 854 dbSNP
rs1024647356 859 dbSNP
rs1166689284 872 dbSNP
rs1415935037 886 dbSNP
rs1410158574 891 dbSNP
rs1192925007 897 dbSNP
rs1400508051 900 dbSNP
rs1239479517 905 dbSNP
rs1177227144 916 dbSNP
rs966436647 916 dbSNP
rs1319484506 923 dbSNP
rs1057139293 934 dbSNP
rs1347537159 938 dbSNP
rs112317911 942 dbSNP
rs886063177 943 dbSNP
rs936927595 961 dbSNP
rs1021854369 964 dbSNP
rs559329364 969 dbSNP
rs1311601237 977 dbSNP
rs1392002948 980 dbSNP
rs968595071 985 dbSNP
rs1235315880 997 dbSNP
rs1286698661 1006 dbSNP
rs1372929295 1011 dbSNP
rs1296653203 1025 dbSNP
rs922122104 1031 dbSNP
rs1375840436 1035 dbSNP
rs1172718016 1047 dbSNP
rs1432808307 1050 dbSNP
rs1326728629 1053 dbSNP
rs1223067007 1055 dbSNP
rs998738105 1065 dbSNP
rs1159261180 1069 dbSNP
rs1031595823 1074 dbSNP
rs1284849980 1075 dbSNP
rs954357981 1076 dbSNP
rs987168936 1109 dbSNP
rs1183244771 1110 dbSNP
rs574284547 1114 dbSNP
rs1485763369 1115 dbSNP
rs1258685654 1126 dbSNP
rs528047531 1127 dbSNP
rs548282373 1136 dbSNP
rs1256151534 1148 dbSNP
rs1485002380 1157 dbSNP
rs910288485 1160 dbSNP
rs1262990971 1164 dbSNP
rs1239927461 1172 dbSNP
rs1316407120 1179 dbSNP
rs1304876952 1197 dbSNP
rs879227200 1198 dbSNP
rs907918005 1220 dbSNP
rs183480271 1226 dbSNP
rs973194242 1227 dbSNP
rs1249172714 1232 dbSNP
rs186657710 1239 dbSNP
rs1362442528 1246 dbSNP
rs1289372999 1252 dbSNP
rs920057884 1254 dbSNP
rs1361576828 1257 dbSNP
rs1166230988 1263 dbSNP
rs550843544 1278 dbSNP
rs940771454 1297 dbSNP
rs1187734524 1306 dbSNP
rs1159569116 1310 dbSNP
rs1410775834 1320 dbSNP
rs1264559844 1348 dbSNP
rs1206242518 1350 dbSNP
rs1485793265 1352 dbSNP
rs1259060125 1356 dbSNP
rs778764070 1369 dbSNP
rs1413307330 1373 dbSNP
rs1037676706 1374 dbSNP
rs899189884 1377 dbSNP
rs995416991 1379 dbSNP
rs1055489998 1380 dbSNP
rs1342149564 1382 dbSNP
rs931487994 1383 dbSNP
rs1381605685 1390 dbSNP
rs1382648150 1390 dbSNP
rs570652277 1391 dbSNP
rs574967270 1410 dbSNP
rs1013334346 1414 dbSNP
rs1024783132 1425 dbSNP
rs1162339737 1431 dbSNP
rs1416703476 1433 dbSNP
rs539776425 1434 dbSNP
rs886063178 1435 dbSNP
rs1375152113 1436 dbSNP
rs1306398884 1441 dbSNP
rs1194281176 1445 dbSNP
rs1428472719 1447 dbSNP
rs1260220482 1454 dbSNP
rs1335456913 1458 dbSNP
rs966404236 1474 dbSNP
rs192470614 1487 dbSNP
rs1212071483 1493 dbSNP
rs1341680113 1501 dbSNP
rs1488831196 1501 dbSNP
rs1226384410 1506 dbSNP
rs1047303298 1508 dbSNP
rs908835212 1509 dbSNP
rs938673043 1512 dbSNP
rs573209438 1515 dbSNP
rs1057085034 1519 dbSNP
rs957984732 1524 dbSNP
rs185714620 1528 dbSNP
rs535445109 1535 dbSNP
rs1347891468 1541 dbSNP
rs1466881573 1548 dbSNP
rs1396719912 1550 dbSNP
rs1168894366 1552 dbSNP
rs1212485449 1556 dbSNP
rs577744213 1576 dbSNP
rs1461777873 1585 dbSNP
rs1272028680 1593 dbSNP
rs1013388851 1603 dbSNP
rs1196060188 1606 dbSNP
rs555839637 1609 dbSNP
rs776701095 1611 dbSNP
rs1234909576 1635 dbSNP
rs1477251719 1637 dbSNP
rs575602477 1642 dbSNP
rs998727955 1646 dbSNP
rs1337194120 1652 dbSNP
rs544858713 1654 dbSNP
rs987612297 1660 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 91147.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' aggcggacaGACUUGUCACu 5'
                   || :|||||| 
Target 5' ----uaauaCU-GACAGUGa 3'
 		1 - 15
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000453321.3 | 3UTR | UAAUACUGACAGUGAGGC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.464 1.3e-2 0.569 2.3e-3 23 Click to see details
GSE38226 Liver fibrosis 0.325 7.5e-2 -0.027 4.5e-1 21 Click to see details
GSE28544 Breast cancer -0.299 7.8e-2 0.010 4.8e-1 24 Click to see details
GSE32688 Pancreatic cancer -0.231 1.0e-1 -0.207 1.3e-1 32 Click to see details
GSE28260 Renal cortex and medulla 0.324 1.4e-1 0.604 1.4e-2 13 Click to see details
GSE26953 Aortic valvular endothelial cells -0.076 3.6e-1 -0.023 4.6e-1 24 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.07 3.7e-1 0.053 4.0e-1 25 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
55 hsa-miR-1208 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT076103 ADORA2B adenosine A2b receptor 2 2
MIRT447464 OSMR oncostatin M receptor 2 2
MIRT448145 ESF1 ESF1 nucleolar pre-rRNA processing protein homolog 2 2
MIRT463639 YY1 YY1 transcription factor 2 4
MIRT465065 TSR1 TSR1, ribosome maturation factor 2 2
MIRT468464 SET SET nuclear proto-oncogene 2 4
MIRT480171 CALM3 calmodulin 3 2 2
MIRT481495 ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 2 8
MIRT484111 ABCD2 ATP binding cassette subfamily D member 2 2 4
MIRT499834 PCSK9 proprotein convertase subtilisin/kexin type 9 2 8
MIRT500261 ZNF788 zinc finger family member 788 2 6
MIRT500551 XBP1P1 X-box binding protein 1 pseudogene 1 2 8
MIRT502697 CSNK1G1 casein kinase 1 gamma 1 2 4
MIRT517786 EFCAB11 EF-hand calcium binding domain 11 2 2
MIRT519191 IVD isovaleryl-CoA dehydrogenase 2 2
MIRT523114 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT527425 NRL neural retina leucine zipper 2 2
MIRT529509 IYD iodotyrosine deiodinase 2 2
MIRT533705 TMEM67 transmembrane protein 67 2 2
MIRT535694 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT536141 MAPK14 mitogen-activated protein kinase 14 2 2
MIRT544878 ZNF543 zinc finger protein 543 2 4
MIRT551362 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT555949 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT561498 SRSF2 serine and arginine rich splicing factor 2 2 2
MIRT569681 AMACR alpha-methylacyl-CoA racemase 2 2
MIRT572518 KIAA0232 KIAA0232 2 2
MIRT572877 OPHN1 oligophrenin 1 2 2
MIRT572924 PRAMEF1 PRAME family member 1 2 2
MIRT607528 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2 2
MIRT611076 ZNF621 zinc finger protein 621 2 2
MIRT613236 CCDC39 coiled-coil domain containing 39 2 2
MIRT616542 NFATC2 nuclear factor of activated T-cells 2 2 2
MIRT620010 CCDC137 coiled-coil domain containing 137 2 2
MIRT621491 STYK1 serine/threonine/tyrosine kinase 1 2 2
MIRT622379 SALL1 spalt like transcription factor 1 2 2
MIRT628226 FBXL20 F-box and leucine rich repeat protein 20 2 2
MIRT636458 LRCH3 leucine rich repeats and calponin homology domain containing 3 2 2
MIRT636546 FAM126B family with sequence similarity 126 member B 2 2
MIRT637350 PIGP phosphatidylinositol glycan anchor biosynthesis class P 2 2
MIRT637604 ZNF554 zinc finger protein 554 2 2
MIRT637732 EXO5 exonuclease 5 2 2
MIRT638697 GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 2 2
MIRT640634 ZIC4 Zic family member 4 2 2
MIRT641535 SNW1 SNW domain containing 1 2 2
MIRT648796 VPS8 VPS8, CORVET complex subunit 2 2
MIRT663060 LRIF1 ligand dependent nuclear receptor interacting factor 1 2 2
MIRT666581 RHOBTB3 Rho related BTB domain containing 3 2 2
MIRT699206 FYN FYN proto-oncogene, Src family tyrosine kinase 2 2
MIRT704875 CD164 CD164 molecule 2 2
MIRT706850 DNAJB13 DnaJ heat shock protein family (Hsp40) member B13 2 2
MIRT712941 CCBE1 collagen and calcium binding EGF domains 1 2 3
MIRT714653 FSTL1 follistatin like 1 2 2
MIRT722320 SH2D1A SH2 domain containing 1A 2 2
MIRT722535 EPRS glutamyl-prolyl-tRNA synthetase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1208 Fulvestrant 17756771 NSC719276 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-1208 Sunitinib 5329102 NSC750690 approved sensitive High Renal Cell Cancer tissue
hsa-miR-1208 Cisplatin 5460033 NSC119875 approved sensitive Low Renal Cell Cancer cell line (Caki-1)
hsa-mir-1208 Dabrafenib 44462760 NSC764134 approved resistant cell line (A375)
hsa-mir-1208 Paclitaxel 36314 NSC125973 approved resistant cell line (W1)
hsa-mir-1208 Androstenedione+Letrozole sensitive cell line (MCF-7)
hsa-miR-1208 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-1208 Doxorubicin 31703 NSC123127 approved resistant cell line (HS578T)
hsa-miR-1208 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-1208 Paclitaxel 36314 NSC125973 approved resistant cell line (A2780)
hsa-miR-1208 Cisplatin 5460033 NSC119875 approved sensitive cell line (RPMI2650)
hsa-miR-1208 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1208 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)
hsa-miR-1208 Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-1208 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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