miRTarBase - #MIRT538462


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pre-miRNA Information
pre-miRNA hsa-mir-3618   
Genomic Coordinates chr22: 20085746 - 20085833
Description Homo sapiens miR-3618 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3618
Sequence 52| UGUCUACAUUAAUGAAAAGAGC |73
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 11 22 + 20085807 27587585 MiREDiBase
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30730356 3 COSMIC
COSN30178222 4 COSMIC
COSN26973254 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs12159555 4 dbSNP
rs761877586 8 dbSNP
Putative Targets

Gene Information
Gene Symbol CNBP   
Synonyms CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Description CCHC-type zinc finger nucleic acid binding protein
Transcript NM_001127192   
Other Transcripts NM_001127193 , NM_001127194 , NM_001127195 , NM_001127196 , NM_003418   
Expression
Putative miRNA Targets on CNBP
3'UTR of CNBP
(miRNA target sites are highlighted)		 
>CNBP|NM_001127192|3'UTR
   1 TTATTTTCCTTTGTCGCCCCTCCTTTTTCTGATTGATGGTTGTATTATTTTCTCTGAATCCTCTTCACTGGCCAAAGGTT
  81 GGCAGATAGAGGCAACTCCCAGGCCAGTGAGCTTTACTTGCCGTGTAAAAGGAGGAAAGGGGTGGAAAAAAACCGACTTT
 161 CTGCATTTAACTACAAAAAAAGTTTATGTTTAGTTTGGTAGAGGTGTTATGTATAATGCTTTGTTAAAGAACCCCCTTTC
 241 CGTGCCACTGGTGAATAGGGATTGATGAATGGGAAGAGTTGAGTCAGACCAGTAAGCCCGTCCTGGGTTCCTTGAACATG
 321 TTCCCATGTAGGAGGTAAAACCAATTCTGGAAGTGTCTATGAACTTCCATAAATAACTTTAATTTTAGTATAATGATGGT
 401 CTTGGATTGTCTGACCTCAGTAGCTATTAAATAACATCAAGTAACATCTGTATCAGGCCCTACATAGAACATACAGTTGA
 481 GTGGGAGTAAACAAAAAGATAAACATGCGTGTTAATGGCTGTTCGAGAGAAATCGGAATAAAAGCCTAAACAGGAACAAC
 561 TTCATCACAGTGTTGATGTTGGACACATAGATGGTGATGGCAAAGGTTTAGAACACATTATTTTCAAAGACTAAATCTAA
 641 AACCCAGAGTAAACATCAATGCTCAGAGTTAGCATAATTTGGAGCTATTCAGGAATTGCAGAGAAATGCATTTTCACAGA
 721 AATCAAGATGTTATTTTTGTATACTATATCACTTAGACAACTGTGTTTCATTTGCTGTAATCAGTTTTTAAAAGTCAGAT
 801 GGAAAGAGCAACTGAAGTCCTAGAAAATAGAAATGTAATTTTAAACTATTCCAATAAAGCTGGAGGAGGAAGGGGAGTTT
 881 GACTAAAGTTCTTTTTGTTTGTTTCAAATTTTCATTAATGTATATAGTGCAAAATACCATATTAAAGAGGGGAATGTGGA
 961 GGACTGAAAGCTGACAGTTTGGACTTTTCTTTTTGTACTTAAGTCATGTCTTCAATAATGAAAATTGCTGTTAAAAGGAT
1041 GTATGGGATTTAGATACTTTTGCAAAGCTATAGAAAATTCACTTTGTAATCTGTTATAATAATGCCCTTGAGTTCTGTGT
1121 TCAGTCTGAACAGGTTTTTTGGTGGTGGTGGTTTTGTTTTGTTTTGGAGACGGAGTCTCACTCTTGTCGCCCAGGCTGGA
1201 GTGCAGGCTTGGCTCACTGCAACCTCCACCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATT
1281 ACAGGCACCCGCCACCACCCCCCGCTAATTTTTTGTATTTTTATTTTTATTTTATTTTTTTATTTTTTTTTGAGACAGAG
1361 TGTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCGTGCCATT
1441 CTCCTGCCTCAGCCTCCTGAGTAGCTGGGGCTACAGGTACCCGCCACCGCGCCCAGCTAATTTTTTTTTTTTGTATTTTT
1521 AGTAAAGACGGGGTTTCACGGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAA
1601 AGTGCTGGGATCACAGGCGTGAGCCACCGCGCCCGGCCTATTTTTTGTATTTTTAGTAGAGACTGGGTTTCATCATGTTG
1681 GTCGGGCTGGTCTCCAACTCCTGACCTCAGGTGATCCACCTGCCCCGCCCCCCAAAGTGCTAGTGTTACAGGTGCGAGCC
1761 ACCGTGTCTGGCCGATTCTGAACAGTTTTAATACCATTGCTATTTTTGTGTTTTTCCTGGGCCTTTTTTTTTTTTTTTTT
1841 TTTTTTTGAGACAGTCTCGCTCTGTTGCCCAGGCTAGAGTGCAATGGTGCAATCTCAGCTCACTGCAACCTCCACCCCCC
1921 ACCCCCACACCCCGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGGTGTCCGCCACCACACCCA
2001 GCTAATTTTTGTTATTTTTAGTAGAGATGGGGTTTCACTGTGTTGGTCAGGCTGGTCTCCAACTGTTGCCCTCAGGTGAG
2081 CCACTGTGCCCCACCTTTTCCTGGGTTTCATAAGGATCTGAAGTGGTGGATTCCTTGTTTTTGCTAGTGTCTCATTTAGA
2161 GTTGAGATGGACCTTAAAACTCATCTGTTTTAACTCACTTTTTAATAGATGAGTTAAACTTAATTTACTTAAGGATGTAC
2241 AGTTAGAGCCTGGAACTTCAACCATTATTCACTCCCCATGCCCTGTTTCCCCCCACTTCGAAATTAAATGCGGTTAGCAT
2321 CATATAGTTCATTTTCCCCCTCCATGCTGCTGTGTGATTCTTGACTTTGGGTATGAGTTTTTCATCCTTCATGCAGGGTT
2401 CTGTCAGTTCATGGTATAGTGATTCAGTGTTAAAATGGTGGTGTCTCAGCTGTGCTGTGCACATTCCAACCTTGTCAAAT
2481 TAATAGTCCTGAGCAAGCAAGAAAAAGAGGTAATAACATACCCATTTCTTTATGAATATAAGCTTATAATATTTTTTCAT
2561 GTGCTATTTTTACTGAGCAAATTGTATGTCTCACATGTTAACACAATAAATATCTTGACAATTTTATTTTCTACCATAAA
2641 AAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cgagAAAAGUAAUUACAUCUGu 5'
              |||||||||||||| |: 
Target 5' caaaTTTTCATTAATGTATATa 3'
 905 - 926 142.00 -14.00
2 
miRNA  3' cgAGAAAAGUAAUUACAUCUGu 5'
            |: |||::||  || |||| 
Target 5' ttTTGTTTTGTT-TTGGAGACg 3'
 1152 - 1172 127.00 -5.70
3 
miRNA  3' cgAGAAAAGUAAUUA-CAUCUgu 5'
            |:||| :|||  | |||||  
Target 5' atTTTTTGTATTTTTAGTAGAga 3'
 1640 - 1662 116.00 -7.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30475916 8 COSMIC
COSN31580759 9 COSMIC
COSN14030860 16 COSMIC
COSN22788315 47 COSMIC
COSN28194740 58 COSMIC
COSN30506446 67 COSMIC
COSN31576158 71 COSMIC
COSN31576813 72 COSMIC
COSN30574784 83 COSMIC
COSN14030856 94 COSMIC
COSN30500221 108 COSMIC
COSN31590362 120 COSMIC
COSN30535997 142 COSMIC
COSN30145247 155 COSMIC
COSN31587563 155 COSMIC
COSN7816958 292 COSMIC
COSN1913102 381 COSMIC
COSN31490888 448 COSMIC
COSN24973629 484 COSMIC
COSN26639277 631 COSMIC
COSN31515082 785 COSMIC
COSN31813671 806 COSMIC
COSN31549031 830 COSMIC
COSN31813190 830 COSMIC
COSN31483377 913 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs946165526 7 dbSNP
rs1345251468 8 dbSNP
rs773186953 8 dbSNP
rs1174529636 9 dbSNP
rs768633993 15 dbSNP
rs762869420 16 dbSNP
rs1194506840 19 dbSNP
rs374265085 20 dbSNP
rs769656607 21 dbSNP
rs769851733 21 dbSNP
rs746102562 22 dbSNP
rs1215763319 24 dbSNP
rs761619634 28 dbSNP
rs781438677 32 dbSNP
rs369630926 33 dbSNP
rs1277636114 35 dbSNP
rs1322422778 36 dbSNP
rs1278228243 45 dbSNP
rs747431509 47 dbSNP
rs1246894639 50 dbSNP
rs1337827924 51 dbSNP
rs200247971 60 dbSNP
rs563712054 63 dbSNP
rs1422128729 64 dbSNP
rs767316332 69 dbSNP
rs911240822 75 dbSNP
rs1453274417 89 dbSNP
rs754877422 93 dbSNP
rs1296763518 98 dbSNP
rs1344619768 100 dbSNP
rs1377594842 104 dbSNP
rs1415944570 111 dbSNP
rs1273346282 117 dbSNP
rs986743882 122 dbSNP
rs185345442 123 dbSNP
rs1393772186 128 dbSNP
rs1308743369 137 dbSNP
rs1317172522 139 dbSNP
rs1303779770 143 dbSNP
rs1238908983 145 dbSNP
rs1025675502 146 dbSNP
rs1349696181 149 dbSNP
rs1211593125 153 dbSNP
rs1236819084 153 dbSNP
rs915855660 154 dbSNP
rs1056094821 155 dbSNP
rs1439334143 156 dbSNP
rs1308147500 161 dbSNP
rs938542827 163 dbSNP
rs530093605 165 dbSNP
rs928438202 171 dbSNP
rs1397349715 173 dbSNP
rs1435715704 174 dbSNP
rs1173619701 175 dbSNP
rs1431151454 182 dbSNP
rs1399400646 188 dbSNP
rs1006580255 193 dbSNP
rs1478147474 203 dbSNP
rs1445584365 206 dbSNP
rs971790894 209 dbSNP
rs1306621555 210 dbSNP
rs1379157124 216 dbSNP
rs1372987098 219 dbSNP
rs559920241 225 dbSNP
rs940483675 232 dbSNP
rs894374836 241 dbSNP
rs181536071 242 dbSNP
rs984500847 245 dbSNP
rs1055508996 248 dbSNP
rs1207185757 268 dbSNP
rs953142466 272 dbSNP
rs1255104639 273 dbSNP
rs1455013034 279 dbSNP
rs1276586076 282 dbSNP
rs1423436355 285 dbSNP
rs1029264318 290 dbSNP
rs906961880 295 dbSNP
rs976709383 299 dbSNP
rs550757124 300 dbSNP
rs1464634534 312 dbSNP
rs763406752 318 dbSNP
rs577411965 326 dbSNP
rs914694507 327 dbSNP
rs188684945 330 dbSNP
rs1365144521 332 dbSNP
rs942967623 339 dbSNP
rs1296196042 342 dbSNP
rs1289574454 350 dbSNP
rs1317429091 355 dbSNP
rs762456914 359 dbSNP
rs1338255372 360 dbSNP
rs1469089492 368 dbSNP
rs986796453 369 dbSNP
rs11542608 378 dbSNP
rs1245347526 395 dbSNP
rs1332853040 396 dbSNP
rs544104333 397 dbSNP
rs1423508051 399 dbSNP
rs1477232589 409 dbSNP
rs1167943945 416 dbSNP
rs1419317170 419 dbSNP
rs1405601927 436 dbSNP
rs1022785470 440 dbSNP
rs1289418713 447 dbSNP
rs1012269334 448 dbSNP
rs1339799807 452 dbSNP
rs868230107 454 dbSNP
rs114097371 464 dbSNP
rs184319958 465 dbSNP
rs1006051420 469 dbSNP
rs1287972773 470 dbSNP
rs1283042675 487 dbSNP
rs1196175636 492 dbSNP
rs761663799 492 dbSNP
rs1216915386 493 dbSNP
rs763542462 494 dbSNP
rs191776002 499 dbSNP
rs1487602137 504 dbSNP
rs1034235205 505 dbSNP
rs571695801 508 dbSNP
rs762048627 509 dbSNP
rs186903970 515 dbSNP
rs1159054587 516 dbSNP
rs201702356 522 dbSNP
rs1041498948 524 dbSNP
rs538353584 525 dbSNP
rs1314638367 533 dbSNP
rs1235822728 534 dbSNP
rs1447358124 538 dbSNP
rs1282684246 544 dbSNP
rs1186874752 548 dbSNP
rs184262675 549 dbSNP
rs1224486297 550 dbSNP
rs777026411 552 dbSNP
rs1213717955 557 dbSNP
rs372368171 559 dbSNP
rs549669948 563 dbSNP
rs892866315 564 dbSNP
rs984922528 564 dbSNP
rs1470963771 568 dbSNP
rs1207037978 570 dbSNP
rs1178790912 587 dbSNP
rs1055070876 590 dbSNP
rs1417616047 607 dbSNP
rs1175491697 610 dbSNP
rs942873863 616 dbSNP
rs1225975910 618 dbSNP
rs879628098 623 dbSNP
rs890043713 624 dbSNP
rs1337544792 626 dbSNP
rs1447885866 628 dbSNP
rs1051248516 629 dbSNP
rs1375211037 637 dbSNP
rs1236917971 661 dbSNP
rs538162697 663 dbSNP
rs879912345 665 dbSNP
rs934011971 673 dbSNP
rs768953942 674 dbSNP
rs976361777 687 dbSNP
rs972691467 699 dbSNP
rs1275895566 701 dbSNP
rs941482101 709 dbSNP
rs909962267 717 dbSNP
rs1237164008 723 dbSNP
rs1437636407 725 dbSNP
rs985039651 730 dbSNP
rs1318202097 731 dbSNP
rs1433900239 733 dbSNP
rs966320151 734 dbSNP
rs1034288879 739 dbSNP
rs1031247500 740 dbSNP
rs981330190 746 dbSNP
rs1398802735 748 dbSNP
rs1466188632 753 dbSNP
rs1161036131 756 dbSNP
rs1330981704 756 dbSNP
rs1398418411 762 dbSNP
rs971288393 763 dbSNP
rs1299258357 767 dbSNP
rs978280710 767 dbSNP
rs1231786617 769 dbSNP
rs758546403 794 dbSNP
rs1272414958 799 dbSNP
rs552305223 801 dbSNP
rs968187553 801 dbSNP
rs1256824094 812 dbSNP
rs567591927 817 dbSNP
rs1412930863 819 dbSNP
rs1012713236 822 dbSNP
rs747502966 828 dbSNP
rs1196733328 842 dbSNP
rs746605807 850 dbSNP
rs549283048 851 dbSNP
rs1007472450 860 dbSNP
rs1473197487 867 dbSNP
rs1245026739 882 dbSNP
rs1294341043 883 dbSNP
rs369504917 885 dbSNP
rs895151658 894 dbSNP
rs1186977683 905 dbSNP
rs1464557482 913 dbSNP
rs1218511429 921 dbSNP
rs565482398 922 dbSNP
rs889928361 924 dbSNP
rs1003491636 926 dbSNP
rs1246606718 927 dbSNP
rs1265640105 929 dbSNP
rs1355427110 930 dbSNP
rs530157240 932 dbSNP
rs1249047379 937 dbSNP
rs1263520918 937 dbSNP
rs907157224 938 dbSNP
rs1036217605 939 dbSNP
rs1218323015 946 dbSNP
rs1450423270 949 dbSNP
rs1192761596 950 dbSNP
rs1261212871 952 dbSNP
rs1476222366 958 dbSNP
rs1165816197 959 dbSNP
rs1289840283 960 dbSNP
rs1456548982 964 dbSNP
rs1051192567 969 dbSNP
rs559777131 981 dbSNP
rs934267397 983 dbSNP
rs150234979 984 dbSNP
rs1037472826 988 dbSNP
rs1361058783 992 dbSNP
rs1397235506 994 dbSNP
rs941335392 995 dbSNP
rs1312756317 1004 dbSNP
rs909957923 1007 dbSNP
rs1294682867 1010 dbSNP
rs990894192 1013 dbSNP
rs532458771 1015 dbSNP
rs768519268 1018 dbSNP
rs927142196 1024 dbSNP
rs1227231557 1027 dbSNP
rs887576660 1032 dbSNP
rs1182553447 1039 dbSNP
rs1255500467 1051 dbSNP
rs981256482 1054 dbSNP
rs971345455 1061 dbSNP
rs1381381698 1062 dbSNP
rs1365414306 1070 dbSNP
rs1290448348 1071 dbSNP
rs1020206807 1085 dbSNP
rs1167545326 1090 dbSNP
rs376812164 1097 dbSNP
rs1324188017 1098 dbSNP
rs1407014890 1103 dbSNP
rs375196609 1105 dbSNP
rs1377721946 1108 dbSNP
rs1393990324 1110 dbSNP
rs1310987956 1112 dbSNP
rs1387171624 1113 dbSNP
rs988891447 1121 dbSNP
rs1449118072 1123 dbSNP
rs1313905278 1137 dbSNP
rs1390977889 1141 dbSNP
rs776203492 1142 dbSNP
rs772207138 1146 dbSNP
rs1482315294 1147 dbSNP
rs1033194243 1151 dbSNP
rs1238987839 1152 dbSNP
rs1439272342 1153 dbSNP
rs1477273032 1153 dbSNP
rs1040093951 1155 dbSNP
rs1006613223 1162 dbSNP
rs889513848 1164 dbSNP
rs746968183 1165 dbSNP
rs778920548 1166 dbSNP
rs770978971 1167 dbSNP
rs141948051 1171 dbSNP
rs562162363 1172 dbSNP
rs1400619741 1174 dbSNP
rs968216650 1176 dbSNP
rs1306827418 1177 dbSNP
rs1369381583 1179 dbSNP
rs1219810415 1180 dbSNP
rs757736024 1184 dbSNP
rs749388189 1186 dbSNP
rs1310557997 1188 dbSNP
rs1220575645 1189 dbSNP
rs897418876 1192 dbSNP
rs1203759243 1193 dbSNP
rs1043320717 1202 dbSNP
rs1342209557 1205 dbSNP
rs1037245540 1214 dbSNP
rs1005982957 1215 dbSNP
rs991000626 1217 dbSNP
rs561283051 1218 dbSNP
rs538709680 1222 dbSNP
rs1003523267 1223 dbSNP
rs1172223892 1227 dbSNP
rs961335642 1230 dbSNP
rs1406714872 1232 dbSNP
rs1328867253 1234 dbSNP
rs372197094 1235 dbSNP
rs1368581654 1241 dbSNP
rs1004720195 1242 dbSNP
rs1429236868 1245 dbSNP
rs1292691394 1246 dbSNP
rs1365432707 1254 dbSNP
rs938102923 1256 dbSNP
rs1278921649 1268 dbSNP
rs1355166578 1282 dbSNP
rs887619485 1286 dbSNP
rs542907216 1290 dbSNP
rs1431589714 1291 dbSNP
rs1221341596 1298 dbSNP
rs1424920165 1299 dbSNP
rs996012490 1300 dbSNP
rs542252577 1301 dbSNP
rs778953451 1303 dbSNP
rs1045628708 1304 dbSNP
rs1415549708 1304 dbSNP
rs1040125394 1307 dbSNP
rs944369225 1308 dbSNP
rs949831889 1309 dbSNP
rs1363408433 1315 dbSNP
rs35464692 1315 dbSNP
rs923569332 1321 dbSNP
rs1182056709 1323 dbSNP
rs1483128203 1330 dbSNP
rs1042666228 1334 dbSNP
rs1298713864 1334 dbSNP
rs1398198292 1335 dbSNP
rs553305178 1337 dbSNP
rs1380198805 1339 dbSNP
rs988721968 1340 dbSNP
rs915489116 1341 dbSNP
rs1218060096 1342 dbSNP
rs1285903018 1342 dbSNP
rs957274892 1342 dbSNP
rs1207596846 1343 dbSNP
rs1487571111 1343 dbSNP
rs1190427810 1347 dbSNP
rs1238641602 1352 dbSNP
rs538737244 1352 dbSNP
rs551895830 1352 dbSNP
rs1383211448 1357 dbSNP
rs1159216886 1358 dbSNP
rs1421260473 1358 dbSNP
rs925665495 1360 dbSNP
rs1336264468 1361 dbSNP
rs1491392003 1361 dbSNP
rs193271369 1364 dbSNP
rs959549463 1365 dbSNP
rs757530455 1368 dbSNP
rs1241289550 1373 dbSNP
rs982131777 1374 dbSNP
rs961364929 1375 dbSNP
rs1015508150 1376 dbSNP
rs961499502 1377 dbSNP
rs556201842 1386 dbSNP
rs1005503978 1396 dbSNP
rs1374153391 1397 dbSNP
rs1016271620 1401 dbSNP
rs952088053 1402 dbSNP
rs1005827329 1403 dbSNP
rs888680561 1408 dbSNP
rs1055172788 1410 dbSNP
rs1468542268 1414 dbSNP
rs188671495 1419 dbSNP
rs781017873 1421 dbSNP
rs1413956654 1422 dbSNP
rs1358759051 1428 dbSNP
rs752827897 1428 dbSNP
rs1447720674 1432 dbSNP
rs1177376961 1433 dbSNP
rs6792159 1434 dbSNP
rs1345154722 1435 dbSNP
rs949884002 1438 dbSNP
rs1260655169 1442 dbSNP
rs1410192078 1443 dbSNP
rs1458827173 1444 dbSNP
rs183700287 1446 dbSNP
rs1473169274 1453 dbSNP
rs900306705 1458 dbSNP
rs1378102875 1461 dbSNP
rs1018715915 1470 dbSNP
rs1477634607 1472 dbSNP
rs1174386074 1475 dbSNP
rs373552698 1480 dbSNP
rs534029889 1482 dbSNP
rs1170218148 1483 dbSNP
rs1237736665 1484 dbSNP
rs12639262 1488 dbSNP
rs1326883733 1489 dbSNP
rs925853803 1491 dbSNP
rs1331059889 1494 dbSNP
rs1228944180 1495 dbSNP
rs1318602130 1500 dbSNP
rs1309278732 1501 dbSNP
rs985099426 1504 dbSNP
rs1319384130 1508 dbSNP
rs1218927894 1509 dbSNP
rs1378500552 1512 dbSNP
rs11401192 1513 dbSNP
rs1250392346 1513 dbSNP
rs143447614 1513 dbSNP
rs1337705026 1515 dbSNP
rs1450967911 1515 dbSNP
rs1454774753 1516 dbSNP
rs953674570 1520 dbSNP
rs1386909474 1521 dbSNP
rs1193261245 1522 dbSNP
rs1244129887 1524 dbSNP
rs1371583925 1525 dbSNP
rs1459591872 1527 dbSNP
rs1320244525 1529 dbSNP
rs547437972 1530 dbSNP
rs1366019814 1532 dbSNP
rs1300574534 1533 dbSNP
rs1163259505 1534 dbSNP
rs1422782428 1539 dbSNP
rs922373100 1540 dbSNP
rs1185123131 1541 dbSNP
rs1265876154 1542 dbSNP
rs1358447565 1550 dbSNP
rs1220223517 1555 dbSNP
rs976441220 1556 dbSNP
rs879288935 1557 dbSNP
rs1193065618 1564 dbSNP
rs1259678639 1565 dbSNP
rs1425788793 1566 dbSNP
rs961097490 1573 dbSNP
rs1368317030 1574 dbSNP
rs532658670 1575 dbSNP
rs530445358 1581 dbSNP
rs1361773057 1582 dbSNP
rs1209075796 1585 dbSNP
rs1419578748 1585 dbSNP
rs1486705021 1586 dbSNP
rs1382130835 1587 dbSNP
rs1263659922 1596 dbSNP
rs1243955988 1598 dbSNP
rs1015784949 1600 dbSNP
rs1311115322 1601 dbSNP
rs1354339424 1605 dbSNP
rs1321262644 1612 dbSNP
rs1214906118 1616 dbSNP
rs565265519 1618 dbSNP
rs1484271827 1619 dbSNP
rs1201297681 1626 dbSNP
rs1006133532 1628 dbSNP
rs550235839 1629 dbSNP
rs1320344919 1630 dbSNP
rs368154408 1631 dbSNP
rs531828845 1634 dbSNP
rs1467103041 1635 dbSNP
rs1302874117 1636 dbSNP
rs561145522 1637 dbSNP
rs1449936679 1640 dbSNP
rs1034315552 1646 dbSNP
rs1002209530 1650 dbSNP
rs906510195 1655 dbSNP
rs1314062542 1663 dbSNP
rs542917432 1667 dbSNP
rs1025076925 1674 dbSNP
rs1262536520 1681 dbSNP
rs1008612965 1683 dbSNP
rs902262334 1684 dbSNP
rs1239229531 1688 dbSNP
rs1480498251 1695 dbSNP
rs1176025490 1697 dbSNP
rs1447316672 1700 dbSNP
rs892541653 1701 dbSNP
rs1389208059 1704 dbSNP
rs1052991740 1705 dbSNP
rs1042110701 1706 dbSNP
rs904440678 1709 dbSNP
rs1430142779 1710 dbSNP
rs946390624 1713 dbSNP
rs1296199817 1715 dbSNP
rs1369667037 1716 dbSNP
rs1387222800 1717 dbSNP
rs1209167693 1723 dbSNP
rs894072469 1726 dbSNP
rs1055358388 1727 dbSNP
rs1220743886 1727 dbSNP
rs1307094909 1728 dbSNP
rs938190078 1729 dbSNP
rs1292623867 1731 dbSNP
rs572363470 1732 dbSNP
rs560110217 1733 dbSNP
rs544705169 1735 dbSNP
rs1479159914 1737 dbSNP
rs952953572 1744 dbSNP
rs1195455582 1749 dbSNP
rs1419829701 1749 dbSNP
rs116852696 1751 dbSNP
rs76579965 1753 dbSNP
rs544292131 1755 dbSNP
rs190331793 1756 dbSNP
rs892558464 1763 dbSNP
rs370844051 1764 dbSNP
rs12633752 1769 dbSNP
rs187327217 1770 dbSNP
rs1322686085 1771 dbSNP
rs1049535034 1773 dbSNP
rs974654943 1774 dbSNP
rs1369384935 1777 dbSNP
rs9881147 1778 dbSNP
rs1168204110 1781 dbSNP
rs1463135276 1794 dbSNP
rs1474880725 1802 dbSNP
rs1184402305 1803 dbSNP
rs200193915 1808 dbSNP
rs1375730419 1815 dbSNP
rs1415753754 1817 dbSNP
rs566744187 1821 dbSNP
rs1480743445 1824 dbSNP
rs1363662542 1828 dbSNP
rs1319066300 1830 dbSNP
rs1421374550 1830 dbSNP
rs1271014376 1844 dbSNP
rs1179901711 1845 dbSNP
rs1286158352 1847 dbSNP
rs1159060129 1848 dbSNP
rs1238873432 1848 dbSNP
rs1241426882 1848 dbSNP
rs1245745868 1848 dbSNP
rs1284429111 1848 dbSNP
rs1313310491 1848 dbSNP
rs1319645998 1848 dbSNP
rs1356485579 1848 dbSNP
rs1380406015 1848 dbSNP
rs1445895327 1848 dbSNP
rs1491575942 1848 dbSNP
rs57560229 1848 dbSNP
rs1398995642 1849 dbSNP
rs1491428004 1849 dbSNP
rs1336207058 1850 dbSNP
rs1407147889 1852 dbSNP
rs1482149219 1853 dbSNP
rs1272374627 1855 dbSNP
rs1196607182 1856 dbSNP
rs112606287 1858 dbSNP
rs1335147676 1861 dbSNP
rs1379569508 1867 dbSNP
rs1254658965 1868 dbSNP
rs1241579681 1870 dbSNP
rs1233035925 1876 dbSNP
rs1349111537 1877 dbSNP
rs1346514956 1880 dbSNP
rs1202631385 1882 dbSNP
rs1241101158 1884 dbSNP
rs1458911566 1886 dbSNP
rs1285813057 1891 dbSNP
rs1468496870 1895 dbSNP
rs1174403360 1896 dbSNP
rs190011929 1901 dbSNP
rs1469544824 1905 dbSNP
rs34121423 1906 dbSNP
rs185205817 1908 dbSNP
rs901092510 1910 dbSNP
rs1334523471 1911 dbSNP
rs34453888 1912 dbSNP
rs1040723460 1914 dbSNP
rs1345576748 1915 dbSNP
rs1392792150 1917 dbSNP
rs1222573296 1918 dbSNP
rs939650919 1919 dbSNP
rs550056735 1920 dbSNP
rs982618313 1921 dbSNP
rs1269766020 1922 dbSNP
rs375592071 1926 dbSNP
rs1426076027 1927 dbSNP
rs1462635579 1927 dbSNP
rs1167703401 1928 dbSNP
rs1431144105 1929 dbSNP
rs35661727 1933 dbSNP
rs1472186982 1934 dbSNP
rs1280757930 1940 dbSNP
rs1327847583 1942 dbSNP
rs1232386824 1946 dbSNP
rs1269448734 1946 dbSNP
rs1337189797 1948 dbSNP
rs764876598 1956 dbSNP
rs749984795 1958 dbSNP
rs1490151194 1961 dbSNP
rs764698140 1962 dbSNP
rs1265337585 1964 dbSNP
rs1429407085 1969 dbSNP
rs1254391367 1985 dbSNP
rs1192727769 1987 dbSNP
rs1203254880 1988 dbSNP
rs1473959812 1990 dbSNP
rs761506718 1998 dbSNP
rs1265310939 1999 dbSNP
rs1423228597 2001 dbSNP
rs1227101617 2006 dbSNP
rs145051505 2015 dbSNP
rs1382496347 2021 dbSNP
rs1317171582 2023 dbSNP
rs1324511085 2024 dbSNP
rs1018830744 2025 dbSNP
rs1240616150 2028 dbSNP
rs1338170882 2029 dbSNP
rs1333165297 2038 dbSNP
rs1452913024 2039 dbSNP
rs1408037914 2040 dbSNP
rs1247924345 2043 dbSNP
rs1318229846 2044 dbSNP
rs1008727561 2046 dbSNP
rs1408680102 2049 dbSNP
rs980917581 2060 dbSNP
rs764546386 2062 dbSNP
rs1204816453 2068 dbSNP
rs1025197731 2077 dbSNP
rs1444295916 2095 dbSNP
rs988160809 2097 dbSNP
rs956896845 2098 dbSNP
rs1032439791 2103 dbSNP
rs1366791993 2110 dbSNP
rs1020697528 2114 dbSNP
rs1453818292 2118 dbSNP
rs1001384790 2130 dbSNP
rs1461895855 2147 dbSNP
rs528001881 2148 dbSNP
rs9880375 2149 dbSNP
rs1337220904 2151 dbSNP
rs1207169799 2152 dbSNP
rs1446758116 2159 dbSNP
rs1309019378 2166 dbSNP
rs1028149959 2167 dbSNP
rs545673318 2170 dbSNP
rs901108651 2173 dbSNP
rs1040901934 2180 dbSNP
rs1353733157 2183 dbSNP
rs1204540867 2187 dbSNP
rs1003902542 2206 dbSNP
rs886747476 2209 dbSNP
rs1055792562 2210 dbSNP
rs938236146 2211 dbSNP
rs1251910609 2223 dbSNP
rs1048047174 2224 dbSNP
rs1157736410 2229 dbSNP
rs1361552712 2231 dbSNP
rs1470782904 2232 dbSNP
rs772724600 2234 dbSNP
rs149175255 2246 dbSNP
rs931079489 2247 dbSNP
rs1046579928 2248 dbSNP
rs56763410 2249 dbSNP
rs180737447 2256 dbSNP
rs1403467619 2259 dbSNP
rs949492578 2272 dbSNP
rs1388682178 2274 dbSNP
rs1347458211 2283 dbSNP
rs1170260625 2289 dbSNP
rs1224410316 2289 dbSNP
rs1262717941 2292 dbSNP
rs984195975 2293 dbSNP
rs565429431 2294 dbSNP
rs956962949 2295 dbSNP
rs988768621 2295 dbSNP
rs1162952401 2299 dbSNP
rs145251732 2300 dbSNP
rs975817653 2311 dbSNP
rs545118050 2312 dbSNP
rs1428190622 2313 dbSNP
rs1431039224 2316 dbSNP
rs1172278396 2320 dbSNP
rs1029002355 2322 dbSNP
rs760171976 2325 dbSNP
rs540459900 2331 dbSNP
rs573060132 2335 dbSNP
rs1218565474 2336 dbSNP
rs1367575912 2339 dbSNP
rs987326230 2340 dbSNP
rs1405663932 2341 dbSNP
rs1450333540 2341 dbSNP
rs996640530 2342 dbSNP
rs1343876014 2344 dbSNP
rs1216542397 2348 dbSNP
rs557809721 2348 dbSNP
rs1296811522 2352 dbSNP
rs1307255668 2360 dbSNP
rs1203083702 2368 dbSNP
rs1290429229 2369 dbSNP
rs577867734 2373 dbSNP
rs1490641951 2376 dbSNP
rs149706654 2377 dbSNP
rs1267476393 2381 dbSNP
rs1476876313 2401 dbSNP
rs1021134838 2406 dbSNP
rs1420029114 2407 dbSNP
rs1360947081 2408 dbSNP
rs571556654 2417 dbSNP
rs1166444227 2419 dbSNP
rs58395398 2422 dbSNP
rs774458329 2425 dbSNP
rs776358032 2425 dbSNP
rs1363771114 2429 dbSNP
rs1004566723 2437 dbSNP
rs887013776 2442 dbSNP
rs1048575686 2443 dbSNP
rs995148724 2445 dbSNP
rs763905667 2459 dbSNP
rs1412059142 2467 dbSNP
rs1317538783 2468 dbSNP
rs567026320 2468 dbSNP
rs1010621077 2469 dbSNP
rs1245882055 2472 dbSNP
rs1290475906 2477 dbSNP
rs1449356001 2481 dbSNP
rs904945058 2485 dbSNP
rs1271653671 2488 dbSNP
rs770963173 2491 dbSNP
rs1434234976 2494 dbSNP
rs1485313978 2507 dbSNP
rs1186463173 2508 dbSNP
rs1044812323 2510 dbSNP
rs1445224178 2511 dbSNP
rs556480605 2513 dbSNP
rs1162822662 2514 dbSNP
rs949543584 2515 dbSNP
rs1402555428 2516 dbSNP
rs918117018 2518 dbSNP
rs115036251 2521 dbSNP
rs573636612 2524 dbSNP
rs192379625 2525 dbSNP
rs1339183367 2540 dbSNP
rs1367518820 2542 dbSNP
rs1452612316 2543 dbSNP
rs749510564 2545 dbSNP
rs1353425039 2549 dbSNP
rs1224993674 2552 dbSNP
rs1284282545 2553 dbSNP
rs1409539228 2554 dbSNP
rs1316035046 2559 dbSNP
rs906821597 2560 dbSNP
rs531678707 2566 dbSNP
rs139580350 2572 dbSNP
rs1182706599 2583 dbSNP
rs1004353078 2584 dbSNP
rs1471086704 2590 dbSNP
rs887245110 2595 dbSNP
rs1477345114 2596 dbSNP
rs186990300 2597 dbSNP
rs979851989 2597 dbSNP
rs1455900762 2599 dbSNP
rs1133046 2603 dbSNP
rs953342693 2605 dbSNP
rs1407351255 2607 dbSNP
rs777863307 2607 dbSNP
rs976111018 2608 dbSNP
rs777327279 2610 dbSNP
rs1200763411 2613 dbSNP
rs1279684124 2617 dbSNP
rs1371952569 2617 dbSNP
rs1490715951 2619 dbSNP
rs1271775663 2621 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 7555.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cgagaAAAGUAAUUACAUCUGu 5'
               ||||||||||||| |: 
Target 5' -----UUUCAUUAAUGUAUAUa 3'
 		1 - 17
Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000502976.1 | 3UTR | UUUCAUUAAUGUAUAUAGUGCAAAAUACCAUAUUAAAGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
29 hsa-miR-3618 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT378435 SOX4 SRY-box 4 2 2
MIRT459627 GABARAP GABA type A receptor-associated protein 2 2
MIRT471295 PGAM4 phosphoglycerate mutase family member 4 2 2
MIRT471369 PDZD8 PDZ domain containing 8 2 2
MIRT504886 MRPL51 mitochondrial ribosomal protein L51 2 2
MIRT505938 RBM33 RNA binding motif protein 33 2 8
MIRT525461 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT526767 ZNF527 zinc finger protein 527 2 2
MIRT526990 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT528669 PDE4DIP phosphodiesterase 4D interacting protein 2 6
MIRT538462 CNBP CCHC-type zinc finger nucleic acid binding protein 2 2
MIRT542899 HSBP1 heat shock factor binding protein 1 2 2
MIRT550274 AHI1 Abelson helper integration site 1 2 2
MIRT551674 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT551689 ASB16 ankyrin repeat and SOCS box containing 16 2 2
MIRT551755 TRIM42 tripartite motif containing 42 2 2
MIRT555769 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 2
MIRT556241 MARCH9 membrane associated ring-CH-type finger 9 2 2
MIRT556926 IRF2BP2 interferon regulatory factor 2 binding protein 2 2 4
MIRT562638 ARID1A AT-rich interaction domain 1A 2 2
MIRT571348 RPL37 ribosomal protein L37 2 2
MIRT612818 KLHL3 kelch like family member 3 2 2
MIRT619329 TIPRL TOR signaling pathway regulator 2 4
MIRT653927 SERPINC1 serpin family C member 1 2 2
MIRT659150 DDHD1 DDHD domain containing 1 2 2
MIRT688334 FAM126B family with sequence similarity 126 member B 2 2
MIRT694760 FZD2 frizzled class receptor 2 2 2
MIRT700477 PUM1 pumilio RNA binding family member 1 2 2
MIRT702375 KLF10 Kruppel like factor 10 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3618 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-3618 Paclitaxel 36314 NSC125973 approved sensitive cell line (W1)
hsa-mir-3618 Cisplatin 5460033 NSC119875 approved sensitive cell line (W1)
hsa-mir-3618 Methotrexate 126941 NSC740 approved sensitive cell line (W1)
hsa-mir-3618 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-3618 Tamoxifen 2733525 NSC180973 approved resistant cell line (LCC2)
hsa-miR-3618 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-3618 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-3618 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide/Methotrexate/Gemcitabine resistant cell line (Bats-72)
hsa-miR-3618 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide resistant cell line (Bads-200)

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