miRTarBase - #MIRT539307


—
pre-miRNA Information
pre-miRNA hsa-mir-1306   
Genomic Coordinates chr22: 20086058 - 20086142
Synonyms MIRN1306, hsa-mir-1306, MIR1306
Description Homo sapiens miR-1306 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1306-5p
Sequence 15| CCACCUCCCCUGCAAACGUCCA |36
Evidence Not_experimental
Experiments
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSM5858927 8 COSMIC
COSM8222405 15 COSMIC
COSM1032175 17 COSMIC
COSM122562 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1197492175 14 dbSNP
rs1245517093 17 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol AKIRIN1   
Synonyms C1orf108, STRF2
Description akirin 1
Transcript NM_001136275   
Other Transcripts NM_024595   
Expression
Putative miRNA Targets on AKIRIN1
3'UTR of AKIRIN1
(miRNA target sites are highlighted)		 
>AKIRIN1|NM_001136275|3'UTR
   1 AGCTTTGTCACATATCTGGGTACCAGGTTTGACCTCAAGAGATGGCTGCTGTACACTTTTTGCAACTGGTTTGATGTCAC
  81 ATTTCAGCTCCAACTTTGCATCCTGAGAACACTTAAACGTTTCTGCAGGTCCATTTTATACAACTTGAAAGACCGTAAAA
 161 CTTTCTGGTTGCCACAAGCATATCTTTCTTTTCTGCTCATCCAATAAACAGCTGTGCCCTACTGTGATAGATTTTCCAAA
 241 CAAAAATACCTGGAGCAGCAGTTTAGCAAAATATGCCTTCAGTGGCATTCAACAAATGGAGTTTCCCCAAGCACAGTTCT
 321 GTAAGAAGTGCGTGTGAGAGTGTGTGTATATGTGTGTATGTGTATTTTAAGTTATTATTTGTATTGTGCAAAAATTTTTT
 401 TTTGATCTTGGGGATTCTGGCTGTGAATTTGGTGCACGACAATTATGGTAAAAAAACATTTGCTTGGTCTAAAGAAGATC
 481 ATTAATGTTTTGTGACCATACAAGTTGTAACAGTGGATTGTTTTTATGTGTAGGTATTGTTAAATACAGGGACTGTTTCC
 561 AGGCACAGAATATGAATCGTAAGTTAGGATGGACATTAGATGTGATTATGATGATAAAGCGAAGGTCTGCGGTCCTATAT
 641 CTACAGACACGTGGTGAGAAATTAGAACAAACTGGAGACGGGCCATTGACACATGGACTCTGCCTGGGCATGTTAGGTTA
 721 ATTCTTTGACTCCAAGCCTTAAAATACTCACATGGAGTCAGCGCTCACCTCATTCACACAATTATCATAGAGCTCCCTGG
 801 ACACTGAACCTCTAAAGGGAAAAGGTCTACCCTGGAGCCAGGAGCATCAGGGTTGGCTTGGGAGCATGAGAGGTGAGCCC
 881 AGGGCTAGGCCTGGGCCAGGCCCCGGCAGCACTGCTACTTGGGAGGAGCCACTTCACCTTTGTATTAGTTATTAAAAAAT
 961 ATAATTTGGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCGAGGCATGCGGATCACTTGAGGTC
1041 AGGAGTTCGAGACCACCCTGGCCAATATGGTGAAACCCCATCTCTACTAAAAATACAACAAAGTTAGCCGGGCGTGGTGG
1121 CAGGCGTCTGTAATCCCAGCTGCTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCTGGAGGTGGCGGTTGCAGTGAGC
1201 ACAGATCATGCCACTGCACTCCAGCCTGGGCAACAAAACGAGACTTCGTCTCAAAAAAAAAAAAAAAACATAGAATTTGG
1281 ATCCTTTGGTCGGGTTCTCCCAAATTCTTTTGAGGTGTCCATGGTCAACTGCTTCAGCTTTGTTTTGGCAACCCCCTGCC
1361 CGAAGTCGCATATAGGCTGTTCTTCACCTTGTTTCCAAGGCTGAGGAACAGAAAGTAGCCTCTGTTTTGAGGAGGTGGAA
1441 GTTAAGTATACATTTATTTTTTACTGTGACTTGTTCAGGACCACATTTTACAAAATGCCTTGTTTCCTTCATTGTTTCTG
1521 GAAAGGAAAGTTCTATTAATATTGTTTTACTTTGAATATAGAATAGTTTTTTTAATTAGGGCTTATTTTGAAAAATTCTG
1601 AGTTTAATTCAAATGTATGCCAATACCTTCCAAAGTAAGGTAATATTCAGAGACAGTTGTTGTGATCAGATGGCTTAGAG
1681 AAATTTCTGGAATATTCACATTCGAAGATTCCTTATTAATGAATGTCTTTGACTTAAATCTAACCAAAAACTGCAACATT
1761 ATTCTTTGTACATTTTCATTATATAGTGTTAACAAGCTTAGTTGCAAACAAATAAAATACTTAAGCTATTTGTTTACCTT
1841 GCCTTCTTAATACTGTGATAATGTTTATTAATTCAAATAACTTATGTGAGAGCTGCTATAACCATTTCCCCAGTTCAACA
1921 TTGCATTGAAAATTTATGGACCTTTAAAAAAAAAAGCCCAACAGTGATTTTTTTTTAATAATTAAAGAATGATTTTACTT
2001 TGTATTTGAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' accuGCAAACGUCCCCUCCACc 5'
              :||||   | ||||||| 
Target 5' cctcTGTTT--TGAGGAGGTGg 3'
 1419 - 1438 150.00 -17.60
2 
miRNA  3' accugcaAAC--GUCCCCUCCACc 5'
                 |||  |   ||||||| 
Target 5' gaatcacTTGAACCCTGGAGGTGg 3'
 1163 - 1186 141.00 -15.30
3 
miRNA  3' accugcaaaCGUCCCCUCCACc 5'
                   ||| | |||||| 
Target 5' ggcttgggaGCATGAGAGGTGa 3'
 855 - 876 125.00 -13.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31545746 7 COSMIC
COSN30145779 17 COSMIC
COSN26965687 19 COSMIC
COSN30156457 37 COSMIC
COSN26508010 63 COSMIC
COSN30738798 95 COSMIC
COSN13543023 119 COSMIC
COSN13543028 127 COSMIC
COSN13543029 134 COSMIC
COSN20073987 148 COSMIC
COSN13543030 156 COSMIC
COSN30127298 169 COSMIC
COSN30115523 231 COSMIC
COSN16320331 251 COSMIC
COSN20090208 478 COSMIC
COSN31565531 550 COSMIC
COSN31577313 557 COSMIC
COSN31567716 579 COSMIC
COSN8638278 584 COSMIC
COSN29426741 618 COSMIC
COSN26275725 628 COSMIC
COSN26570012 638 COSMIC
COSN26275726 642 COSMIC
COSN31593556 680 COSMIC
COSN17338062 706 COSMIC
COSN26548990 718 COSMIC
COSN28759440 878 COSMIC
COSN31960221 1126 COSMIC
COSN15661671 1270 COSMIC
COSN19468670 1540 COSMIC
COSN29187760 1660 COSMIC
COSN23079007 1882 COSMIC
COSN28286824 1947 COSMIC
COSN28902517 1956 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1284950958 3 dbSNP
rs1200053251 4 dbSNP
rs1469086107 4 dbSNP
rs780507019 12 dbSNP
rs747365633 15 dbSNP
rs1400659600 16 dbSNP
rs149817455 18 dbSNP
rs371972577 20 dbSNP
rs1488690045 24 dbSNP
rs1164374843 25 dbSNP
rs376888630 27 dbSNP
rs1261708348 35 dbSNP
rs560428173 38 dbSNP
rs1188709025 39 dbSNP
rs772698878 44 dbSNP
rs200624052 45 dbSNP
rs1472265105 47 dbSNP
rs1161356793 51 dbSNP
rs558298991 60 dbSNP
rs1419819253 63 dbSNP
rs766200358 65 dbSNP
rs372089533 66 dbSNP
rs1397496987 67 dbSNP
rs1478401187 68 dbSNP
rs759259138 74 dbSNP
rs767272913 75 dbSNP
rs112358934 76 dbSNP
rs757539408 77 dbSNP
rs765455481 82 dbSNP
rs1458493597 86 dbSNP
rs750499638 88 dbSNP
rs1202629122 89 dbSNP
rs540498199 94 dbSNP
rs1347770852 98 dbSNP
rs981187259 104 dbSNP
rs760096142 115 dbSNP
rs780449239 116 dbSNP
rs1468988178 119 dbSNP
rs1358453850 120 dbSNP
rs1441106556 120 dbSNP
rs1181335080 124 dbSNP
rs1239651735 130 dbSNP
rs747493258 141 dbSNP
rs755304220 142 dbSNP
rs781618322 144 dbSNP
rs1377287744 145 dbSNP
rs747859259 149 dbSNP
rs11547140 155 dbSNP
rs1401203386 156 dbSNP
rs1450237062 165 dbSNP
rs1172774555 166 dbSNP
rs1333574080 167 dbSNP
rs928487643 168 dbSNP
rs934470049 172 dbSNP
rs574293996 174 dbSNP
rs769418667 175 dbSNP
rs1164923654 180 dbSNP
rs748518608 181 dbSNP
rs761309826 198 dbSNP
rs772754035 201 dbSNP
rs1200938974 203 dbSNP
rs748814525 205 dbSNP
rs1457935070 212 dbSNP
rs1177692429 213 dbSNP
rs914473781 217 dbSNP
rs1247785583 218 dbSNP
rs770413746 219 dbSNP
rs1199455295 220 dbSNP
rs1377034980 230 dbSNP
rs1341071320 231 dbSNP
rs1467996617 234 dbSNP
rs1401697069 241 dbSNP
rs1223950474 242 dbSNP
rs774157040 246 dbSNP
rs759510287 250 dbSNP
rs145873918 253 dbSNP
rs561299381 256 dbSNP
rs149002326 257 dbSNP
rs1387455865 258 dbSNP
rs1263326358 265 dbSNP
rs1043695370 269 dbSNP
rs1308929582 272 dbSNP
rs1221837278 273 dbSNP
rs536186747 275 dbSNP
rs932776346 282 dbSNP
rs1051117090 283 dbSNP
rs891322540 285 dbSNP
rs1266638197 297 dbSNP
rs1004365582 301 dbSNP
rs1486738732 308 dbSNP
rs1016278230 322 dbSNP
rs898714386 329 dbSNP
rs564050687 331 dbSNP
rs777067715 333 dbSNP
rs1426957995 341 dbSNP
rs144507104 347 dbSNP
rs1193074906 348 dbSNP
rs969705126 349 dbSNP
rs1167080521 359 dbSNP
rs1217391360 365 dbSNP
rs1385944057 367 dbSNP
rs1002654594 372 dbSNP
rs374677838 372 dbSNP
rs772898881 375 dbSNP
rs1301562492 378 dbSNP
rs1224921602 384 dbSNP
rs1162243581 390 dbSNP
rs1343135075 392 dbSNP
rs1282138920 395 dbSNP
rs1400062911 395 dbSNP
rs1343005204 408 dbSNP
rs192501029 415 dbSNP
rs1453509566 420 dbSNP
rs1360060219 436 dbSNP
rs759841694 438 dbSNP
rs546514050 439 dbSNP
rs184426490 443 dbSNP
rs535699624 447 dbSNP
rs1487681427 448 dbSNP
rs1288650890 450 dbSNP
rs1184650970 451 dbSNP
rs1360908301 452 dbSNP
rs114649333 455 dbSNP
rs776238261 457 dbSNP
rs778157728 457 dbSNP
rs921296354 468 dbSNP
rs1262112133 472 dbSNP
rs1316634225 477 dbSNP
rs532618590 478 dbSNP
rs1382115599 479 dbSNP
rs538264734 482 dbSNP
rs1339160950 493 dbSNP
rs1450896293 499 dbSNP
rs558210569 500 dbSNP
rs773631432 501 dbSNP
rs578060972 502 dbSNP
rs759045345 504 dbSNP
rs912623352 508 dbSNP
rs1467262461 512 dbSNP
rs1371359880 514 dbSNP
rs1318626204 524 dbSNP
rs1168284064 529 dbSNP
rs1037164335 535 dbSNP
rs534394061 535 dbSNP
rs1185208705 536 dbSNP
rs1459813195 551 dbSNP
rs554118337 552 dbSNP
rs1263004864 553 dbSNP
rs898657016 559 dbSNP
rs1249147507 565 dbSNP
rs995808058 569 dbSNP
rs1322866525 576 dbSNP
rs1044656488 578 dbSNP
rs1185687300 579 dbSNP
rs188119069 580 dbSNP
rs1332354013 590 dbSNP
rs1393327563 598 dbSNP
rs753263543 604 dbSNP
rs74067034 609 dbSNP
rs191787539 615 dbSNP
rs1181794169 621 dbSNP
rs955779891 622 dbSNP
rs1382771381 631 dbSNP
rs4147753 638 dbSNP
rs1384349370 642 dbSNP
rs754034280 644 dbSNP
rs1439218921 645 dbSNP
rs1021496742 646 dbSNP
rs968947234 649 dbSNP
rs143669799 651 dbSNP
rs1244392456 652 dbSNP
rs954063283 660 dbSNP
rs116861301 662 dbSNP
rs775066608 680 dbSNP
rs532927177 681 dbSNP
rs377493051 684 dbSNP
rs1338322999 685 dbSNP
rs1306561225 686 dbSNP
rs1387486907 693 dbSNP
rs986734273 695 dbSNP
rs1304924490 703 dbSNP
rs1422704604 704 dbSNP
rs760324852 707 dbSNP
rs1364834626 711 dbSNP
rs1383043817 716 dbSNP
rs1471001494 717 dbSNP
rs1451336190 721 dbSNP
rs546675938 726 dbSNP
rs912640802 732 dbSNP
rs750607210 734 dbSNP
rs763803371 744 dbSNP
rs1375520316 747 dbSNP
rs1224288366 752 dbSNP
rs1306147498 753 dbSNP
rs1287291676 760 dbSNP
rs868408964 763 dbSNP
rs1037516966 764 dbSNP
rs1260414648 765 dbSNP
rs1234200798 773 dbSNP
rs1205300064 784 dbSNP
rs1281482047 786 dbSNP
rs1445330351 788 dbSNP
rs920136022 795 dbSNP
rs1264030141 796 dbSNP
rs560047034 798 dbSNP
rs1461034666 800 dbSNP
rs758157396 803 dbSNP
rs1402288467 805 dbSNP
rs1201912229 807 dbSNP
rs1157674419 813 dbSNP
rs931456665 815 dbSNP
rs779757139 820 dbSNP
rs746961941 823 dbSNP
rs1044688999 826 dbSNP
rs745767804 827 dbSNP
rs1470514970 828 dbSNP
rs1177169001 830 dbSNP
rs4147752 832 dbSNP
rs1284050214 833 dbSNP
rs549270668 838 dbSNP
rs753657279 841 dbSNP
rs1325945704 843 dbSNP
rs1261424531 846 dbSNP
rs1223054894 848 dbSNP
rs569203358 850 dbSNP
rs1318681727 854 dbSNP
rs1270746508 866 dbSNP
rs1406452721 867 dbSNP
rs1324574063 870 dbSNP
rs1468957193 872 dbSNP
rs1453020780 883 dbSNP
rs1164289278 895 dbSNP
rs1173802428 896 dbSNP
rs1468882662 897 dbSNP
rs1419574660 903 dbSNP
rs1002549839 905 dbSNP
rs1355781572 914 dbSNP
rs538225984 922 dbSNP
rs1442231801 924 dbSNP
rs1056777103 927 dbSNP
rs891451111 933 dbSNP
rs551523490 934 dbSNP
rs866220882 938 dbSNP
rs768648325 945 dbSNP
rs1275242390 955 dbSNP
rs1225183477 962 dbSNP
rs761566142 968 dbSNP
rs904378575 970 dbSNP
rs1269452712 971 dbSNP
rs995941646 972 dbSNP
rs571711974 976 dbSNP
rs1322492236 977 dbSNP
rs1334334608 987 dbSNP
rs78361436 990 dbSNP
rs1330326222 991 dbSNP
rs1028879729 992 dbSNP
rs1275330060 1005 dbSNP
rs1419511071 1014 dbSNP
rs1438489528 1017 dbSNP
rs1203883015 1018 dbSNP
rs954594060 1019 dbSNP
rs1183325173 1026 dbSNP
rs554249990 1027 dbSNP
rs1234756631 1028 dbSNP
rs768239092 1037 dbSNP
rs567486130 1049 dbSNP
rs1200676710 1050 dbSNP
rs1223101017 1058 dbSNP
rs1019646119 1059 dbSNP
rs1312678698 1061 dbSNP
rs1479624830 1065 dbSNP
rs145060641 1066 dbSNP
rs1373615518 1071 dbSNP
rs1280923170 1072 dbSNP
rs972866622 1076 dbSNP
rs1353390985 1078 dbSNP
rs1421171179 1079 dbSNP
rs919984073 1087 dbSNP
rs1410081211 1095 dbSNP
rs556420791 1096 dbSNP
rs980235061 1097 dbSNP
rs1368692566 1098 dbSNP
rs1406710606 1110 dbSNP
rs1410518475 1111 dbSNP
rs1175684180 1114 dbSNP
rs1469731292 1115 dbSNP
rs1201626391 1118 dbSNP
rs747662280 1123 dbSNP
rs1289425127 1125 dbSNP
rs1317279311 1126 dbSNP
rs531906583 1127 dbSNP
rs576364144 1130 dbSNP
rs1402821102 1131 dbSNP
rs772774955 1136 dbSNP
rs762601872 1148 dbSNP
rs1349451991 1160 dbSNP
rs373085349 1161 dbSNP
rs1340282827 1163 dbSNP
rs1303071354 1167 dbSNP
rs1214129820 1170 dbSNP
rs938952068 1173 dbSNP
rs765193748 1182 dbSNP
rs1057385374 1183 dbSNP
rs1361610822 1184 dbSNP
rs1223893335 1186 dbSNP
rs891486862 1188 dbSNP
rs945684101 1189 dbSNP
rs1489974936 1215 dbSNP
rs1195735178 1220 dbSNP
rs548429793 1229 dbSNP
rs1475527851 1231 dbSNP
rs1018805173 1235 dbSNP
rs1166897850 1236 dbSNP
rs1042830108 1240 dbSNP
rs1213324043 1241 dbSNP
rs1328062334 1242 dbSNP
rs1387785992 1245 dbSNP
rs1263300991 1246 dbSNP
rs544187602 1249 dbSNP
rs1164156771 1251 dbSNP
rs1348732853 1253 dbSNP
rs1364645364 1253 dbSNP
rs542393644 1253 dbSNP
rs1364865532 1254 dbSNP
rs1287503682 1265 dbSNP
rs1430377644 1266 dbSNP
rs148712732 1269 dbSNP
rs80030342 1269 dbSNP
rs1205145881 1270 dbSNP
rs1384902368 1270 dbSNP
rs1320041876 1271 dbSNP
rs1327309839 1272 dbSNP
rs904241579 1280 dbSNP
rs1254929566 1284 dbSNP
rs995972877 1292 dbSNP
rs184048395 1293 dbSNP
rs1294056215 1304 dbSNP
rs890279424 1307 dbSNP
rs138842575 1313 dbSNP
rs1338989890 1315 dbSNP
rs1450762672 1316 dbSNP
rs539911811 1317 dbSNP
rs1401706190 1322 dbSNP
rs1298832582 1330 dbSNP
rs1463529292 1331 dbSNP
rs772340850 1335 dbSNP
rs1168212162 1347 dbSNP
rs370377538 1352 dbSNP
rs1246771774 1353 dbSNP
rs1385597708 1355 dbSNP
rs1185152270 1360 dbSNP
rs1291735296 1362 dbSNP
rs1357916287 1363 dbSNP
rs776059665 1368 dbSNP
rs1285408570 1369 dbSNP
rs761113062 1373 dbSNP
rs961421470 1374 dbSNP
rs879628230 1386 dbSNP
rs1340100736 1388 dbSNP
rs529077134 1396 dbSNP
rs1307970215 1399 dbSNP
rs764734458 1403 dbSNP
rs4433383 1406 dbSNP
rs575018785 1412 dbSNP
rs1027081886 1413 dbSNP
rs1394390176 1423 dbSNP
rs1306146781 1425 dbSNP
rs1429061150 1439 dbSNP
rs952735454 1441 dbSNP
rs1165249661 1444 dbSNP
rs1422514153 1448 dbSNP
rs1367591814 1450 dbSNP
rs1192064223 1452 dbSNP
rs189132319 1474 dbSNP
rs1245766042 1483 dbSNP
rs1247844455 1500 dbSNP
rs1180765505 1503 dbSNP
rs1490659653 1505 dbSNP
rs1445982284 1519 dbSNP
rs1183635815 1527 dbSNP
rs1384605711 1534 dbSNP
rs754371687 1536 dbSNP
rs1294502074 1539 dbSNP
rs927477377 1548 dbSNP
rs761817917 1551 dbSNP
rs938817746 1555 dbSNP
rs993116680 1557 dbSNP
rs1385411428 1559 dbSNP
rs1399860493 1567 dbSNP
rs913450415 1567 dbSNP
rs1241412844 1574 dbSNP
rs1318815767 1597 dbSNP
rs562760764 1600 dbSNP
rs1287827172 1601 dbSNP
rs745992756 1601 dbSNP
rs376008884 1603 dbSNP
rs561895518 1603 dbSNP
rs796897292 1606 dbSNP
rs1304868146 1609 dbSNP
rs1384912792 1611 dbSNP
rs1338713634 1615 dbSNP
rs1043081585 1616 dbSNP
rs181772912 1623 dbSNP
rs904284150 1624 dbSNP
rs931766354 1628 dbSNP
rs1241812113 1636 dbSNP
rs1409238007 1637 dbSNP
rs1050122134 1639 dbSNP
rs1480475816 1642 dbSNP
rs1271754137 1647 dbSNP
rs372339674 1653 dbSNP
rs796848707 1656 dbSNP
rs11547137 1657 dbSNP
rs1036295790 1658 dbSNP
rs897704260 1668 dbSNP
rs1350436570 1669 dbSNP
rs1207211155 1670 dbSNP
rs1348820076 1673 dbSNP
rs1203731815 1676 dbSNP
rs12091652 1679 dbSNP
rs1325733162 1684 dbSNP
rs1318394745 1687 dbSNP
rs1285159731 1701 dbSNP
rs994185484 1704 dbSNP
rs1027441749 1705 dbSNP
rs1383636001 1709 dbSNP
rs1386084547 1710 dbSNP
rs1319454791 1713 dbSNP
rs952680537 1721 dbSNP
rs1001646764 1733 dbSNP
rs1034414960 1741 dbSNP
rs1477999109 1742 dbSNP
rs1374073735 1756 dbSNP
rs1195863946 1765 dbSNP
rs765318782 1768 dbSNP
rs1421478820 1769 dbSNP
rs1261367353 1773 dbSNP
rs1183945595 1784 dbSNP
rs993376371 1793 dbSNP
rs913491855 1810 dbSNP
rs1229412177 1823 dbSNP
rs1364264019 1824 dbSNP
rs1362740846 1827 dbSNP
rs1469471004 1829 dbSNP
rs1452950256 1843 dbSNP
rs750612601 1848 dbSNP
rs758588199 1853 dbSNP
rs1407780161 1861 dbSNP
rs1408645709 1867 dbSNP
rs1413409640 1877 dbSNP
rs967994693 1884 dbSNP
rs1336245539 1886 dbSNP
rs551656847 1895 dbSNP
rs571511719 1899 dbSNP
rs928975937 1901 dbSNP
rs1241606993 1906 dbSNP
rs1393162510 1921 dbSNP
rs1209589008 1930 dbSNP
rs931632115 1936 dbSNP
rs1273689082 1939 dbSNP
rs185740979 1940 dbSNP
rs1339923904 1943 dbSNP
rs1246361724 1946 dbSNP
rs1282056044 1946 dbSNP
rs1296623446 1946 dbSNP
rs911614486 1946 dbSNP
rs1335653356 1956 dbSNP
rs1049231276 1960 dbSNP
rs1036567986 1968 dbSNP
rs547546697 1968 dbSNP
rs944565210 1968 dbSNP
rs941613134 1977 dbSNP
rs1324647230 1978 dbSNP
rs1223756164 1979 dbSNP
rs999917 1980 dbSNP
rs1482004276 1981 dbSNP
rs1197015100 1982 dbSNP
rs894663499 1999 dbSNP
rs1048992691 2002 dbSNP
rs529339397 2005 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions hESCs (WA-09)
Disease 79647.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in SRR359787. RNA binding protein: AGO2. Condition:4-thiouridine ...

- Lipchina I; Elkabetz Y; Hafner M; Sheridan et al., 2011, Genes & development.

Article - Lipchina I; Elkabetz Y; Hafner M; Sheridan et al.
- Genes & development, 2011
MicroRNAs are important regulators in many cellular processes, including stem cell self-renewal. Recent studies demonstrated their function as pluripotency factors with the capacity for somatic cell reprogramming. However, their role in human embryonic stem (ES) cells (hESCs) remains poorly understood, partially due to the lack of genome-wide strategies to identify their targets. Here, we performed comprehensive microRNA profiling in hESCs and in purified neural and mesenchymal derivatives. Using a combination of AGO cross-linking and microRNA perturbation experiments, together with computational prediction, we identified the targets of the miR-302/367 cluster, the most abundant microRNAs in hESCs. Functional studies identified novel roles of miR-302/367 in maintaining pluripotency and regulating hESC differentiation. We show that in addition to its role in TGF-beta signaling, miR-302/367 promotes bone morphogenetic protein (BMP) signaling by targeting BMP inhibitors TOB2, DAZAP2, and SLAIN1. This study broadens our understanding of microRNA function in hESCs and is a valuable resource for future studies in this area.
LinkOut: [PMID: 22012620]
CLIP-seq Support 1 for dataset SRR359787
Method / RBP PAR-CLIP / AGO2
Cell line / Condition hESCs (WA-09) / 4-thiouridine, RNase T1
Location of target site ENST00000432648.3 | 3UTR | UGGAAGUUAAGUAUACAUUUAUUUUUUACUGUGACUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 22012620 / SRX103431
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
184 hsa-miR-1306-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT089458 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT167143 LHFPL2 LHFPL tetraspan subfamily member 2 2 2
MIRT290873 BCL10 B-cell CLL/lymphoma 10 2 2
MIRT320237 CYCS cytochrome c, somatic 2 2
MIRT462980 ZNF784 zinc finger protein 784 2 2
MIRT478039 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT479102 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 4
MIRT482763 TMEM126B transmembrane protein 126B 2 2
MIRT489972 MCC mutated in colorectal cancers 2 4
MIRT495484 TNFAIP2 TNF alpha induced protein 2 2 2
MIRT496148 GPS1 G protein pathway suppressor 1 2 2
MIRT523370 GSR glutathione-disulfide reductase 2 2
MIRT526299 SORCS2 sortilin related VPS10 domain containing receptor 2 2 4
MIRT527427 NRL neural retina leucine zipper 2 2
MIRT527860 SMOC1 SPARC related modular calcium binding 1 2 6
MIRT529685 FBXL19 F-box and leucine rich repeat protein 19 2 2
MIRT531526 NOM1 nucleolar protein with MIF4G domain 1 2 2
MIRT532461 PLGRKT plasminogen receptor with a C-terminal lysine 2 2
MIRT532519 KCNN1 potassium calcium-activated channel subfamily N member 1 2 2
MIRT532668 APOBEC3D apolipoprotein B mRNA editing enzyme catalytic subunit 3D 2 2
MIRT532718 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT533205 WAPAL WAPL cohesin release factor 2 2
MIRT536480 KIAA1549 KIAA1549 2 2
MIRT537158 GID8 GID complex subunit 8 homolog 2 2
MIRT539307 AKIRIN1 akirin 1 2 2
MIRT539569 CNKSR3 CNKSR family member 3 2 4
MIRT540045 DNAJC28 DnaJ heat shock protein family (Hsp40) member C28 2 4
MIRT540235 SAMD5 sterile alpha motif domain containing 5 2 2
MIRT543016 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT551436 F2 coagulation factor II, thrombin 2 2
MIRT556146 MED12L mediator complex subunit 12 like 2 2
MIRT570714 DGKE diacylglycerol kinase epsilon 2 2
MIRT572037 GRWD1 glutamate rich WD repeat containing 1 2 2
MIRT572409 MRPS14 mitochondrial ribosomal protein S14 2 2
MIRT572660 AGMAT agmatinase 2 4
MIRT611450 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT611601 JAKMIP3 Janus kinase and microtubule interacting protein 3 2 4
MIRT612208 TMEM109 transmembrane protein 109 2 2
MIRT612312 VSIG10 V-set and immunoglobulin domain containing 10 2 2
MIRT614146 MAFK MAF bZIP transcription factor K 2 2
MIRT617371 C21orf62 chromosome 21 open reading frame 62 2 2
MIRT617689 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT618495 DENND5B DENN domain containing 5B 2 4
MIRT618802 SPATA21 spermatogenesis associated 21 2 2
MIRT619061 TTC4 tetratricopeptide repeat domain 4 2 2
MIRT619902 NPTXR neuronal pentraxin receptor 2 2
MIRT620080 DZIP1L DAZ interacting zinc finger protein 1 like 2 2
MIRT622233 SLC25A45 solute carrier family 25 member 45 2 2
MIRT625262 ZNF566 zinc finger protein 566 2 2
MIRT625725 CXorf38 chromosome X open reading frame 38 2 2
MIRT625813 POFUT1 protein O-fucosyltransferase 1 2 2
MIRT625839 NXPE2 neurexophilin and PC-esterase domain family member 2 2 2
MIRT626024 XRCC2 X-ray repair cross complementing 2 2 2
MIRT626054 PDE4C phosphodiesterase 4C 2 2
MIRT626082 CWF19L1 CWF19 like 1, cell cycle control (S. pombe) 2 2
MIRT626356 PACS1 phosphofurin acidic cluster sorting protein 1 2 2
MIRT626790 KCNK6 potassium two pore domain channel subfamily K member 6 2 2
MIRT627797 RAB11FIP1 RAB11 family interacting protein 1 2 2
MIRT628234 FAM212B family with sequence similarity 212 member B 2 2
MIRT628241 FADS1 fatty acid desaturase 1 2 2
MIRT628249 ETF1 eukaryotic translation termination factor 1 2 2
MIRT628799 A2ML1 alpha-2-macroglobulin like 1 2 2
MIRT628879 FAM177A1 family with sequence similarity 177 member A1 2 4
MIRT629333 ZNF487P zinc finger protein 487 1 1
MIRT629435 RPL34 ribosomal protein L34 2 2
MIRT629977 MRPL36 mitochondrial ribosomal protein L36 2 2
MIRT630727 FPR1 formyl peptide receptor 1 2 2
MIRT630776 MSANTD3 Myb/SANT DNA binding domain containing 3 2 2
MIRT631074 ZNF829 zinc finger protein 829 2 2
MIRT633139 C6orf132 chromosome 6 open reading frame 132 2 2
MIRT633178 AGO3 argonaute 3, RISC catalytic component 2 2
MIRT633510 RNF14 ring finger protein 14 2 2
MIRT633613 APCDD1 APC down-regulated 1 2 2
MIRT633668 MYO1F myosin IF 2 2
MIRT633707 LRRC8B leucine rich repeat containing 8 VRAC subunit B 2 2
MIRT633798 SOX7 SRY-box 7 2 2
MIRT634203 TMOD2 tropomodulin 2 2 4
MIRT634297 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT634509 NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2 2
MIRT634518 NKAP NFKB activating protein 2 2
MIRT634754 CRCP CGRP receptor component 2 2
MIRT635741 IFNAR1 interferon alpha and beta receptor subunit 1 2 2
MIRT636480 KLHL7 kelch like family member 7 2 2
MIRT637042 FITM2 fat storage inducing transmembrane protein 2 2 2
MIRT637748 POLR3K RNA polymerase III subunit K 2 2
MIRT638568 IFNE interferon epsilon 2 2
MIRT639155 TMEM167A transmembrane protein 167A 2 2
MIRT639848 ZBTB20 zinc finger and BTB domain containing 20 2 2
MIRT641770 ZNF207 zinc finger protein 207 2 2
MIRT642285 ZNF99 zinc finger protein 99 2 2
MIRT642685 KRT74 keratin 74 2 2
MIRT643530 ERAP2 endoplasmic reticulum aminopeptidase 2 2 2
MIRT643742 ZNF284 zinc finger protein 284 2 4
MIRT643945 WIPF3 WAS/WASL interacting protein family member 3 2 2
MIRT644320 NFKBID NFKB inhibitor delta 2 2
MIRT644383 ZNF286A zinc finger protein 286A 2 2
MIRT645130 HES2 hes family bHLH transcription factor 2 2 2
MIRT645607 PCDH11X protocadherin 11 X-linked 2 2
MIRT647121 ZNF446 zinc finger protein 446 2 2
MIRT648484 CMBL carboxymethylenebutenolidase homolog 2 2
MIRT648549 BBS5 Bardet-Biedl syndrome 5 2 2
MIRT649252 TRIM65 tripartite motif containing 65 2 2
MIRT649468 SLC10A7 solute carrier family 10 member 7 2 2
MIRT650013 KLB klotho beta 2 2
MIRT650068 CCDC134 coiled-coil domain containing 134 2 2
MIRT650325 RTN2 reticulon 2 2 2
MIRT651093 ZNF516 zinc finger protein 516 2 2
MIRT651265 ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2 2
MIRT651272 ZKSCAN1 zinc finger with KRAB and SCAN domains 1 2 2
MIRT651402 ZBTB16 zinc finger and BTB domain containing 16 2 2
MIRT652163 TRIM66 tripartite motif containing 66 2 2
MIRT653153 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 2 2
MIRT653477 SLC4A1 solute carrier family 4 member 1 (Diego blood group) 2 2
MIRT653922 SERPINC1 serpin family C member 1 2 2
MIRT654243 RNF115 ring finger protein 115 2 2
MIRT655354 PCDH11Y protocadherin 11 Y-linked 2 2
MIRT655958 NDST1 N-deacetylase and N-sulfotransferase 1 2 2
MIRT656318 MESDC1 talin rod domain containing 1 2 2
MIRT656578 LSM10 LSM10, U7 small nuclear RNA associated 2 2
MIRT657210 IKZF2 IKAROS family zinc finger 2 2 2
MIRT657856 GJB1 gap junction protein beta 1 2 2
MIRT658207 FBXO44 F-box protein 44 2 2
MIRT659003 DIAPH1 diaphanous related formin 1 2 2
MIRT659349 CSRP1 cysteine and glycine rich protein 1 2 2
MIRT659501 CISD3 CDGSH iron sulfur domain 3 2 2
MIRT659761 CCDC171 coiled-coil domain containing 171 2 2
MIRT660149 BRD4 bromodomain containing 4 2 2
MIRT661582 EPHX2 epoxide hydrolase 2 2 2
MIRT661753 ATM ATM serine/threonine kinase 2 2
MIRT662223 CCRL2 C-C motif chemokine receptor like 2 2 2
MIRT663883 CXorf56 chromosome X open reading frame 56 2 2
MIRT664308 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT664649 GALM galactose mutarotase 2 2
MIRT664671 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 2
MIRT665050 C3 complement C3 2 2
MIRT666467 SCRG1 stimulator of chondrogenesis 1 2 2
MIRT666529 RNF170 ring finger protein 170 2 2
MIRT669118 CDC42BPG CDC42 binding protein kinase gamma 2 2
MIRT669311 C17orf75 chromosome 17 open reading frame 75 2 2
MIRT669358 BHLHE22 basic helix-loop-helix family member e22 2 2
MIRT669691 ABLIM1 actin binding LIM protein 1 2 2
MIRT674223 FAM120AOS family with sequence similarity 120A opposite strand 2 2
MIRT674766 QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 2 2
MIRT675207 ZNF554 zinc finger protein 554 2 2
MIRT675271 ZNF431 zinc finger protein 431 2 2
MIRT676265 PBOV1 prostate and breast cancer overexpressed 1 2 2
MIRT676573 VSIG1 V-set and immunoglobulin domain containing 1 2 2
MIRT677566 C19orf52 translocase of inner mitochondrial membrane 29 2 2
MIRT677631 ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase 2 2
MIRT678115 MICA MHC class I polypeptide-related sequence A 2 2
MIRT678694 RNF157 ring finger protein 157 2 2
MIRT679583 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT679621 MED28 mediator complex subunit 28 2 2
MIRT683700 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT683721 LACTB lactamase beta 2 2
MIRT690967 APOL1 apolipoprotein L1 2 2
MIRT691611 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT702524 KCND3 potassium voltage-gated channel subfamily D member 3 2 2
MIRT704762 CDKN2AIPNL CDKN2A interacting protein N-terminal like 2 2
MIRT708738 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT708898 SKIDA1 SKI/DACH domain containing 1 2 2
MIRT709965 TRUB2 TruB pseudouridine synthase family member 2 2 2
MIRT710373 GM2A GM2 ganglioside activator 2 2
MIRT710533 TMEM201 transmembrane protein 201 2 2
MIRT710582 HLCS holocarboxylase synthetase 2 2
MIRT711030 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT712200 SHROOM4 shroom family member 4 2 2
MIRT713798 CPLX2 complexin 2 2 2
MIRT714096 ZNF486 zinc finger protein 486 2 2
MIRT714923 PPP1R12C protein phosphatase 1 regulatory subunit 12C 2 2
MIRT716518 TNPO2 transportin 2 2 2
MIRT716701 HLA-B major histocompatibility complex, class I, B 2 2
MIRT717070 MTMR6 myotubularin related protein 6 2 2
MIRT719561 CBL Cbl proto-oncogene 2 2
MIRT719688 ALDH1L2 aldehyde dehydrogenase 1 family member L2 2 2
MIRT720134 RIMKLA ribosomal modification protein rimK like family member A 2 2
MIRT720222 IPPK inositol-pentakisphosphate 2-kinase 2 2
MIRT720982 METTL21A methyltransferase like 21A 2 2
MIRT723821 PDS5A PDS5 cohesin associated factor A 2 2
MIRT723999 LMTK2 lemur tyrosine kinase 2 2 2
MIRT724963 PTK6 protein tyrosine kinase 6 2 2
MIRT725217 PEA15 phosphoprotein enriched in astrocytes 15 2 2
MIRT725262 PARVB parvin beta 2 2
MIRT755883 METTL14 methyltransferase like 14 3 1
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1306 Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-mir-1306 Fluorouracil 3385 NSC19893 approved resistant cell line (KYSE)
hsa-miR-1306-5p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia tissue
hsa-miR-1306-5p Paclitaxel 36314 NSC125973 approved sensitive cell line (HS578T)
hsa-miR-1306-5p Doxorubicin 31703 NSC123127 approved sensitive cell line (HS578T)
hsa-miR-1306-5p Cisplatin 5460033 NSC119875 approved resistant cell line (A549)
hsa-miR-1306-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

Error report submission