miRTarBase - #MIRT540681


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pre-miRNA Information
pre-miRNA hsa-mir-1273h   
Genomic Coordinates chr16: 24203116 - 24203231
Description Homo sapiens miR-1273h stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1273h-5p
Sequence 33| CUGGGAGGUCAAGGCUGCAGU |53
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1028034199 14 dbSNP
rs542383563 18 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol BMP3   
Synonyms BMP-3A
Description bone morphogenetic protein 3
Transcript NM_001201   
Expression
Putative miRNA Targets on BMP3
3'UTR of BMP3
(miRNA target sites are highlighted)		 
>BMP3|NM_001201|3'UTR
   1 CCTGGCAAAGAACTCATTTGAATGCTTAATTCAATCATTAGTTTATTTTTATGGACTTCTTCCTGTTTTTTTTTTTTTTT
  81 TTTTTGCACTGCCAATGCATTTTGTTTCAAAAGATTATTTCTATAGTCAGAGGGGAATGAGCAAATAGACTGAAGATTGC
 161 CACCAAGGAAAAGAACTGTATTTGTTTCTGAATGTAACTTAAAGCAAGATTTTTAGTAAATATGGACATCTATTTCTCTT
 241 TTTGTAATCAAACACAACAACTTATCAAACTGTTTTTAGAACTGTTAGAGAACACACTGGTTTATTTTTGTAATGTTCTT
 321 TGAAAACAGAATGGAGAAGCAGCAATAGCTTGTCATTTATCTCATTTAATGACTAATGGGAAATAGAGAACAATTTCGCG
 401 TTTTGAATTAGGCTTATTGCCTTAGAATCCTGAGAAAGTGCTAAATAATCAACTCTGATGTTTTTCTTAAGTTCTTGAGA
 481 CTCTTGTTTATCCTTGTTTTTCCTCCACAAGTCATTGTCTAAGTGTAATGGAAAGTTTATGCTGAGCGTTAGTGTGTATG
 561 TATGTGCGTACATGCGCCAGGTGCCTGTGCCCTCTGTAGGATGGTTTGCTTAATATGGTTTTATAATTCAGTTTACACAG
 641 GATTCTTTATTTTTTTTAATTTTGTATTTTGGCAAACACCATTCAGTTATAAGAACTTTGCCAAATATGATAGAATAATT
 721 CAAGAGCATATACAGAGAGTTACCACTTGACCCAGCTATTTAATTGCAAATACAGTTGTTTTCATTTCATTTCCTACCAG
 801 AAAAAGGAATCAGAAACCTAGTTTTTGAAAACACAAGTGTAATTCCTCTTTTGTACTTCTTTTTCACAAATGCTTTTATT
 881 TATTCTAAATTGAATTTAAAAATCCTTCCTAAAGCCATTAACTCTTTAATTCTCCTGATATGCCTTTACTTCCTATGAAG
 961 TTATTGGTAGATGTTGAGGCCCAAAAACTGGTAGAATATTGAAGATCTTCTTAAATGACCAATTTAACCATAACCAAATA
1041 TTGAATATCATTCTTCAGTCACATCTAAGTCAGGCACTTTTTCACATAGATCAGGGCTTTTGGCTCAGTCACGAAATCTA
1121 CAAGTTAGCAAAGCTTACAAAACATTATTCGTCAGGTATGGGAATCAAATATAGACACTTGTTTGTCTTTGCTTTCCATT
1201 TCTATGTGTCACATACATATATGTGTCCTCTTATAACTTTAGTCTTCAAAATTATTTCAATATCCTTCTTCTCACTATAT
1281 TTATTTGTGTGATGGAAATGCTTTCAGGCCGTAGATCATTGTTGGTGTTAATCTGTGGTTAATCCTCATTTTAGTTCCGT
1361 CTTATCTGATACTTAGAAATATCTCAGCCATTTTGGAGGCTGTGCAGTATCAGAAGACGTGGAGTTTGTTCTGTCTCTGC
1441 CTGTAGCTAATTATGGTGGTTCAGTCATTTAATAAATATGTTTTGAGCATCTATTTTGTGAAAGGCACTGTGTTACCTGT
1521 GTGTCTTTAGTGTCCTCACTGGTAAAATGAAGAGGCTGGCCATGAGCTGGAAGGGTTAAGTTTATAATTCCAGCTATTTC
1601 ACACCCGTCTTCCTTGAAGGAATGATAGTGATAGATATAAAAACACTGTAAGTCCCTCTTTTAATAAACTAAATGAAAGA
1681 ACATCCTATACTTCGCTGTTTGTAAATTAGTATGGCATTCGCTTTGGTTTAAGTGGTATTTTATTGCAAACCCATTAAAA
1761 GAATAACTCATGAAAAGAAGCTCTTTGACACCTTGGGGTACACAAATGTTGGTGTGGGTGTGTGTTAATTCTGTGAGTGA
1841 GACACACCAGTTCTAAAAAAAATGAGTGAAGTTCTGGTGCCTGAGTTACCATGCTTTCTTCTAGTTCTTACAGTAGCATA
1921 AAATTAAAGATTCAAAGTGAGATGGAGGATAAAATTACTTTTTAATACATGTTCTCAAACATTTGAAAATAAAAGTATAT
2001 GATAGAAGGGGGCCAGAGTGTGGCCACCATCCTGATCGTACTGTTTTTCAATAAAGAAAACTTTTTCATTGGTAGATTTG
2081 GTGAAATTCTAAATTTAGGTTTTTTTCTAGAGCTGTATCAACCAAAACTTCTGGCAATTCCCAGTATCACTTCTTAGCCT
2161 TCTTATATCCAAATGCCTGTTTATTACCTTTCTTAATTTGAATCAATGCCTAGTTATTACAGATTGCACCCCACAATGGC
2241 CAAAAACCCACTACATAATAAAATTTACAGGTACTAACTAGTTAAGATTATATTTTAAGTAGCAATTGATATAAAATTAC
2321 AACACAATGAAAGAACTTGGGTAATCTCTTAGCAATGGAAATAGGTTTTAACCAGCAGTTTTTCTGGGTGCTTTGTAACT
2401 ATCATTTTACTAATGAATTGAGGATGTATTATGGTTTAAATTGGAAGAGTTTTATTCCCAAAGAATAAAGCAAGATTATC
2481 TTTCAGTAGTAGAGATTGAAGTAAATGTATTAATATTTTAATTAATACAGATTTACTAAGAGTAGTTAGAAAATTTAGTA
2561 AGTGCCTGTTTTACAAATTGTTAGGTACTAGTTTCTGTATAATTCCTACACAGAAGCTTTAGAAATCTCCTGATATTAAA
2641 TTATTAAATTGGCATTCATGAAAAGAGAAGCTACAATTATAAACTCCATTTGCTAAATCATGCATAATACTCTCTCTCTC
2721 TCTTCCCCCACAAGTAATCTCTCTACCCCATGCAGTGTGCACACACACACACACACAGTCAGTTACTGAAAAAAATAATT
2801 CTTTTTCTTTTTTTTTTTAAATGGAGTTTCACTCTTGTCGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCCCACTGCA
2881 ACCTCCACCTCCCAGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGTCCGCCACCATGCC
2961 TGGCTAATTTTTTTATTTGATAAAAAGAATTCTTTTTCTCAATAACTGTTCTCTTGAATTCAAATTAAGGGACTGCCAAA
3041 GTCAATTAGAATATTTTAAAAATACTTTGTTGTAACCTGTGTAAATAATATACAATTTACAGGATTTGGGATTGTAGAAC
3121 TTAAACTGGAAGACTGGATTCCTCAGATCTCAGGACTATAACATTCCAGATAAATTTTTACATTCCCTTTGCTGTATATT
3201 AACTGATGATCATTTATATGTTAAGATTTTTTACCTTAATATTTCTGAATAAAACTCTTATTGCCCATTTAATATTTTCA
3281 TAGGCAATCAAATGTGAGTAATACTGCTAAGAGTCTGATTTATTAAAAATATTTGTATAATTCATTCAGTTTAGTTTTTC
3361 AGTTTAGTCTTTCTGCTTTCACTTTTCTCTGTGCTAACAAGTAACTAATGTCTGGGCATTGACTTCTTATTGAATCAAAG
3441 TTGGGTTAGGCATAGCTATGCACACCTGATGTGTAAGATTAAAGAAGAGATTAAATAAGAAATCTTGGGTAAGTTGGACT
3521 TTTCTGTATAGCTCTTTTTTCCTCTGAGTTGTATTTTAATGTAGTTTATAAGTGATAAAATGATCCTTGTTTTCTAAAAG
3601 CCAGTCCTTCCCTTCAGCTTTCCACAGTTTCTGTAAATGTTTAATACTTGTACAGTCAATGGCAATTTTAAATATATATA
3681 TATATATAATATATGTATATGGAAAAGGTTCAAAGATGCTTTTAATTTATTTAATGACTATTGCCTTCCTATAATAATAA
3761 TTTTCATCCTTAATTATGATAATACTTTTAGCAAGAAAAATTCCTTTTTACTACAGTTTTTAGATGCAAAATGCAGTTTG
3841 GTTCTTTAGTCAAATCCACTTAGAGGGTATATTGCAGTGAAACTGTGAAGGATACTTCACTACCAATGTATAAGCTTTGT
3921 TGAATTTGTATCATTTTCTTTCAGTAATGAAAAGCTATTCATTATACAGTATGGAAATAAAAATTGCTTCATTGACCATT
4001 CATTTTTACTTATTGGGAAATACTATATTTCCAGACATTTTCAAGTGTGCTGCATTTAAAAGAGGTAATAAAGCTTAAGC
4081 ATAGAGTTG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ugACGUCGGAACUGGAGGGUc 5'
            |||| |||  |||||||| 
Target 5' acTGCAACCTCCACCTCCCAg 3'
 2875 - 2895 171.00 -30.00
2 
miRNA  3' ugacguCGGAACUGGAGGGUc 5'
                ||||| ||:|||:| 
Target 5' tgatatGCCTTTACTTCCTAt 3'
 936 - 956 135.00 -15.00
3 
miRNA  3' ugacguCGGAACUGGAGGGUc 5'
                |:||| :|:|:||| 
Target 5' ttgtttGTCTTTGCTTTCCAt 3'
 1179 - 1199 127.00 -13.70
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30477494 5 COSMIC
COSN31573348 11 COSMIC
COSN30189225 51 COSMIC
COSN30480400 55 COSMIC
COSN25638056 58 COSMIC
COSN30145476 110 COSMIC
COSN30127640 156 COSMIC
COSN26850459 168 COSMIC
COSN31599760 209 COSMIC
COSN31535158 231 COSMIC
COSN31529218 280 COSMIC
COSN31516754 317 COSMIC
COSN31489114 330 COSMIC
COSN8618108 434 COSMIC
COSN31489262 531 COSMIC
COSN29315847 658 COSMIC
COSN8491428 685 COSMIC
COSN2477631 722 COSMIC
COSN14820482 726 COSMIC
COSN31566122 767 COSMIC
COSN31568433 813 COSMIC
COSN32063667 823 COSMIC
COSN5578751 859 COSMIC
COSN2046634 1088 COSMIC
COSN15582917 1339 COSMIC
COSN31962297 1358 COSMIC
COSN7844682 1720 COSMIC
COSN8349877 2045 COSMIC
COSN22276237 2063 COSMIC
COSN29100695 2088 COSMIC
COSN15757461 2144 COSMIC
COSN20091066 2200 COSMIC
COSN21693519 2309 COSMIC
COSN216741 2344 COSMIC
COSN2046635 2348 COSMIC
COSN2046636 2519 COSMIC
COSN15400832 2659 COSMIC
COSN27303853 2723 COSMIC
COSN20100264 2796 COSMIC
COSN31609444 2993 COSMIC
COSN15668393 3059 COSMIC
COSN31535814 3093 COSMIC
COSN27320104 3175 COSMIC
COSN31545037 3193 COSMIC
COSN2046637 3321 COSMIC
COSN31522597 3338 COSMIC
COSN31607522 3348 COSMIC
COSN31596132 3351 COSMIC
COSN31545827 3361 COSMIC
COSN31536680 3457 COSMIC
COSN31521205 3505 COSMIC
COSN28201551 3676 COSMIC
COSN6581980 3850 COSMIC
COSN29878150 3884 COSMIC
COSN2046638 3895 COSMIC
COSN15662943 3950 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs530695825 4 dbSNP
rs984578913 7 dbSNP
rs781457224 17 dbSNP
rs750673028 18 dbSNP
rs1418711632 24 dbSNP
rs990400627 28 dbSNP
rs149057133 30 dbSNP
rs780000725 36 dbSNP
rs1424640063 39 dbSNP
rs749181644 40 dbSNP
rs1387684158 42 dbSNP
rs1210416724 51 dbSNP
rs754989944 53 dbSNP
rs1193673609 54 dbSNP
rs1252253209 63 dbSNP
rs1203461191 64 dbSNP
rs1307368735 65 dbSNP
rs375448689 65 dbSNP
rs1042122004 66 dbSNP
rs1187402466 66 dbSNP
rs1254261142 66 dbSNP
rs1415758639 66 dbSNP
rs1421067730 66 dbSNP
rs1425540677 66 dbSNP
rs1460286637 66 dbSNP
rs1473003317 66 dbSNP
rs1491333140 66 dbSNP
rs1491437614 66 dbSNP
rs371743242 66 dbSNP
rs60606505 66 dbSNP
rs1175799668 67 dbSNP
rs386400624 67 dbSNP
rs1197555520 69 dbSNP
rs1375854953 70 dbSNP
rs1039242104 71 dbSNP
rs1455575899 71 dbSNP
rs1224397903 72 dbSNP
rs901778893 73 dbSNP
rs1232151002 74 dbSNP
rs933211453 74 dbSNP
rs1289855744 77 dbSNP
rs1389418731 80 dbSNP
rs1372320002 83 dbSNP
rs1491059100 85 dbSNP
rs1157241773 86 dbSNP
rs1459379696 86 dbSNP
rs1426795614 87 dbSNP
rs1433627501 88 dbSNP
rs1296617981 92 dbSNP
rs1457857196 97 dbSNP
rs906305260 98 dbSNP
rs1391974845 99 dbSNP
rs1323058176 100 dbSNP
rs879155979 105 dbSNP
rs1193352910 109 dbSNP
rs1467471593 110 dbSNP
rs1252930947 115 dbSNP
rs939129699 118 dbSNP
rs7661611 120 dbSNP
rs867796067 122 dbSNP
rs868717809 123 dbSNP
rs1236419791 128 dbSNP
rs1316042669 131 dbSNP
rs1301641328 144 dbSNP
rs757233501 146 dbSNP
rs1442850674 150 dbSNP
rs903214049 156 dbSNP
rs1368636844 160 dbSNP
rs529438935 168 dbSNP
rs1435777962 174 dbSNP
rs1055343198 177 dbSNP
rs190102711 184 dbSNP
rs1453316478 185 dbSNP
rs1378428300 194 dbSNP
rs1178608103 197 dbSNP
rs1452986108 206 dbSNP
rs1033130291 224 dbSNP
rs369426764 225 dbSNP
rs1252633349 227 dbSNP
rs1263216479 228 dbSNP
rs1202860080 229 dbSNP
rs1256253985 232 dbSNP
rs1480792650 233 dbSNP
rs1345434532 234 dbSNP
rs1208711067 239 dbSNP
rs879125438 242 dbSNP
rs1013088209 243 dbSNP
rs1016840639 254 dbSNP
rs897159518 261 dbSNP
rs1250648924 270 dbSNP
rs1316224043 272 dbSNP
rs1381735777 273 dbSNP
rs1403119465 274 dbSNP
rs1304840481 287 dbSNP
rs1433136530 291 dbSNP
rs1169700830 294 dbSNP
rs778775540 298 dbSNP
rs994151226 300 dbSNP
rs1469741475 305 dbSNP
rs1190341264 310 dbSNP
rs1194141701 316 dbSNP
rs1427443574 328 dbSNP
rs1023530103 330 dbSNP
rs979411277 340 dbSNP
rs1212555914 345 dbSNP
rs151144163 347 dbSNP
rs1172281151 349 dbSNP
rs981715044 350 dbSNP
rs1341311167 355 dbSNP
rs1268366816 364 dbSNP
rs1375001471 364 dbSNP
rs1462742670 369 dbSNP
rs1226729979 373 dbSNP
rs1341106142 376 dbSNP
rs1026565917 379 dbSNP
rs534979298 382 dbSNP
rs1413164429 389 dbSNP
rs950398220 392 dbSNP
rs7678312 399 dbSNP
rs182988931 400 dbSNP
rs1018817092 401 dbSNP
rs1394924118 413 dbSNP
rs1167816343 414 dbSNP
rs367727512 414 dbSNP
rs908967117 418 dbSNP
rs1189525899 421 dbSNP
rs957531908 430 dbSNP
rs990400429 433 dbSNP
rs1380880961 435 dbSNP
rs535421442 437 dbSNP
rs1182572213 438 dbSNP
rs1439373693 449 dbSNP
rs1298260108 450 dbSNP
rs943091804 451 dbSNP
rs974618737 452 dbSNP
rs1357052696 454 dbSNP
rs978134417 457 dbSNP
rs1231544342 458 dbSNP
rs537327415 462 dbSNP
rs927670315 466 dbSNP
rs557572442 487 dbSNP
rs544135640 497 dbSNP
rs1307693779 507 dbSNP
rs1334330640 508 dbSNP
rs574148887 515 dbSNP
rs1328674113 517 dbSNP
rs933135840 531 dbSNP
rs939059265 540 dbSNP
rs1397326999 541 dbSNP
rs1243666569 546 dbSNP
rs1459430065 547 dbSNP
rs1416662019 548 dbSNP
rs1270919874 549 dbSNP
rs1470985754 553 dbSNP
rs1230947716 559 dbSNP
rs1054890039 560 dbSNP
rs1452054652 562 dbSNP
rs894974624 567 dbSNP
rs1329470622 568 dbSNP
rs1336233645 576 dbSNP
rs536355843 577 dbSNP
rs1225672404 580 dbSNP
rs1348895457 582 dbSNP
rs1213785811 585 dbSNP
rs1279266179 592 dbSNP
rs554437350 593 dbSNP
rs574342813 595 dbSNP
rs934667342 596 dbSNP
rs1054825183 604 dbSNP
rs1373762270 617 dbSNP
rs140064899 640 dbSNP
rs1393066164 641 dbSNP
rs746656016 642 dbSNP
rs897107001 647 dbSNP
rs1454572843 650 dbSNP
rs994056313 650 dbSNP
rs1262230109 652 dbSNP
rs1396707157 658 dbSNP
rs1191649795 665 dbSNP
rs1423057577 666 dbSNP
rs1023036043 680 dbSNP
rs1248720830 688 dbSNP
rs1030051858 690 dbSNP
rs754516085 695 dbSNP
rs368040632 708 dbSNP
rs1007349927 710 dbSNP
rs1350463196 711 dbSNP
rs1003034703 717 dbSNP
rs1234182043 724 dbSNP
rs72870289 729 dbSNP
rs1366643544 735 dbSNP
rs1018401209 740 dbSNP
rs1343032100 752 dbSNP
rs1317158582 759 dbSNP
rs1388530640 761 dbSNP
rs185811219 765 dbSNP
rs1011782546 767 dbSNP
rs1171601282 771 dbSNP
rs1290966012 773 dbSNP
rs1453656695 774 dbSNP
rs1420153750 779 dbSNP
rs1363047738 785 dbSNP
rs575538079 788 dbSNP
rs1020479911 790 dbSNP
rs879511674 806 dbSNP
rs544177869 813 dbSNP
rs6831641 815 dbSNP
rs1486808817 817 dbSNP
rs78629796 820 dbSNP
rs990973413 836 dbSNP
rs1267005763 837 dbSNP
rs5004402 840 dbSNP
rs1213369887 845 dbSNP
rs559854321 852 dbSNP
rs1217807659 854 dbSNP
rs1261261699 860 dbSNP
rs377133176 865 dbSNP
rs941183479 870 dbSNP
rs1415016109 872 dbSNP
rs1185532377 881 dbSNP
rs1310784540 889 dbSNP
rs1433890712 891 dbSNP
rs1354994223 892 dbSNP
rs1038137904 894 dbSNP
rs974922861 896 dbSNP
rs923020227 899 dbSNP
rs1188827701 913 dbSNP
rs954576667 924 dbSNP
rs147122908 936 dbSNP
rs1187632470 939 dbSNP
rs1481146668 943 dbSNP
rs1188718130 948 dbSNP
rs1203024131 951 dbSNP
rs1307493923 980 dbSNP
rs1271602025 982 dbSNP
rs923859634 983 dbSNP
rs1495637 985 dbSNP
rs1291089159 988 dbSNP
rs1495636 992 dbSNP
rs1346320861 996 dbSNP
rs537794780 997 dbSNP
rs1434418605 1000 dbSNP
rs1439928007 1007 dbSNP
rs1353862238 1013 dbSNP
rs550946681 1021 dbSNP
rs1006917690 1024 dbSNP
rs1039799631 1032 dbSNP
rs893198011 1047 dbSNP
rs914585032 1052 dbSNP
rs1415073377 1068 dbSNP
rs948747153 1076 dbSNP
rs1020426049 1085 dbSNP
rs1370473458 1098 dbSNP
rs77192228 1109 dbSNP
rs1003530031 1113 dbSNP
rs866012916 1114 dbSNP
rs536418048 1116 dbSNP
rs1208444483 1123 dbSNP
rs1047904362 1124 dbSNP
rs1243594733 1125 dbSNP
rs886706258 1145 dbSNP
rs1317212388 1151 dbSNP
rs73831278 1152 dbSNP
rs1221870794 1156 dbSNP
rs1372480763 1163 dbSNP
rs1016499609 1173 dbSNP
rs1326465080 1175 dbSNP
rs990528808 1178 dbSNP
rs916259552 1179 dbSNP
rs1454444143 1180 dbSNP
rs962411635 1207 dbSNP
rs1211815569 1213 dbSNP
rs764165422 1214 dbSNP
rs1232546146 1216 dbSNP
rs1157317833 1222 dbSNP
rs1418891197 1223 dbSNP
rs1396107045 1224 dbSNP
rs1196021567 1231 dbSNP
rs964769867 1237 dbSNP
rs1250591934 1238 dbSNP
rs1479666806 1240 dbSNP
rs1485956770 1242 dbSNP
rs1262157906 1245 dbSNP
rs879486114 1247 dbSNP
rs1409352538 1265 dbSNP
rs1303956661 1275 dbSNP
rs1236405983 1288 dbSNP
rs572638217 1294 dbSNP
rs929858550 1308 dbSNP
rs1051437135 1311 dbSNP
rs776509819 1312 dbSNP
rs1435750457 1316 dbSNP
rs1376427021 1320 dbSNP
rs1327695799 1326 dbSNP
rs1395020790 1334 dbSNP
rs1453045708 1334 dbSNP
rs1197488801 1336 dbSNP
rs912511723 1337 dbSNP
rs942627466 1348 dbSNP
rs1184393712 1349 dbSNP
rs55807732 1355 dbSNP
rs1298309115 1359 dbSNP
rs1345589293 1360 dbSNP
rs954420288 1360 dbSNP
rs1255376916 1366 dbSNP
rs977913191 1380 dbSNP
rs191716079 1382 dbSNP
rs1238188846 1385 dbSNP
rs765202901 1387 dbSNP
rs1041858501 1395 dbSNP
rs903347851 1399 dbSNP
rs1356341225 1401 dbSNP
rs74904047 1402 dbSNP
rs1036339555 1407 dbSNP
rs1227412686 1414 dbSNP
rs989825613 1416 dbSNP
rs916494983 1419 dbSNP
rs1272476287 1420 dbSNP
rs1477259612 1423 dbSNP
rs948737776 1425 dbSNP
rs1013602853 1428 dbSNP
rs1023216522 1454 dbSNP
rs962360054 1457 dbSNP
rs973783226 1459 dbSNP
rs1206706430 1460 dbSNP
rs544501234 1464 dbSNP
rs1341465517 1465 dbSNP
rs1249621290 1471 dbSNP
rs1044379440 1479 dbSNP
rs1218103482 1490 dbSNP
rs1468406245 1494 dbSNP
rs928723224 1495 dbSNP
rs1025384457 1502 dbSNP
rs1192265160 1503 dbSNP
rs183879078 1507 dbSNP
rs138526836 1511 dbSNP
rs938723170 1514 dbSNP
rs1454926476 1517 dbSNP
rs1047831986 1520 dbSNP
rs1167761695 1521 dbSNP
rs912404948 1533 dbSNP
rs942596010 1543 dbSNP
rs1393578605 1544 dbSNP
rs975336556 1549 dbSNP
rs188884739 1552 dbSNP
rs1006388379 1558 dbSNP
rs1464680879 1560 dbSNP
rs1038392468 1563 dbSNP
rs900717519 1571 dbSNP
rs1166613274 1572 dbSNP
rs144041262 1581 dbSNP
rs1367670578 1585 dbSNP
rs1170496542 1597 dbSNP
rs1439430755 1601 dbSNP
rs750973588 1607 dbSNP
rs528636235 1608 dbSNP
rs551901058 1609 dbSNP
rs938776940 1616 dbSNP
rs755061629 1624 dbSNP
rs1280447765 1628 dbSNP
rs999259819 1646 dbSNP
rs1030688925 1647 dbSNP
rs1334471069 1649 dbSNP
rs192472472 1649 dbSNP
rs1331230617 1657 dbSNP
rs958148890 1665 dbSNP
rs754678513 1670 dbSNP
rs989295752 1676 dbSNP
rs1023976529 1688 dbSNP
rs780665963 1689 dbSNP
rs1429764150 1692 dbSNP
rs1268258670 1695 dbSNP
rs980114159 1696 dbSNP
rs1471057208 1707 dbSNP
rs1361889208 1713 dbSNP
rs1013086864 1714 dbSNP
rs1016502111 1717 dbSNP
rs1254898909 1721 dbSNP
rs1211918495 1722 dbSNP
rs530327267 1726 dbSNP
rs745781556 1731 dbSNP
rs1216590927 1735 dbSNP
rs1207163834 1744 dbSNP
rs1274020421 1745 dbSNP
rs1348961716 1748 dbSNP
rs530778206 1752 dbSNP
rs1334170583 1755 dbSNP
rs182285564 1759 dbSNP
rs146743640 1762 dbSNP
rs748364082 1771 dbSNP
rs1025747243 1785 dbSNP
rs1240760186 1791 dbSNP
rs536937756 1792 dbSNP
rs942199188 1796 dbSNP
rs757672562 1802 dbSNP
rs900767006 1807 dbSNP
rs1358386769 1809 dbSNP
rs1157833057 1810 dbSNP
rs546833238 1817 dbSNP
rs1435198807 1819 dbSNP
rs373214913 1821 dbSNP
rs932223880 1822 dbSNP
rs1189511497 1823 dbSNP
rs964256358 1826 dbSNP
rs187279157 1837 dbSNP
rs1051951869 1844 dbSNP
rs1195573128 1847 dbSNP
rs1445559183 1851 dbSNP
rs1459356608 1852 dbSNP
rs914516421 1855 dbSNP
rs975325201 1855 dbSNP
rs538353121 1856 dbSNP
rs999143050 1859 dbSNP
rs1030716910 1863 dbSNP
rs1432374933 1865 dbSNP
rs1389204668 1867 dbSNP
rs138864615 1868 dbSNP
rs1011175455 1875 dbSNP
rs938740518 1885 dbSNP
rs1400099009 1886 dbSNP
rs1023438877 1889 dbSNP
rs191722702 1891 dbSNP
rs1420304885 1898 dbSNP
rs948927471 1904 dbSNP
rs1037897645 1905 dbSNP
rs1262766486 1910 dbSNP
rs1189041025 1916 dbSNP
rs1486839427 1926 dbSNP
rs1236136377 1929 dbSNP
rs1210013453 1930 dbSNP
rs769917420 1938 dbSNP
rs1308604481 1946 dbSNP
rs1278995830 1948 dbSNP
rs1273028416 1961 dbSNP
rs1215840601 1968 dbSNP
rs1355134247 1973 dbSNP
rs1277150694 1980 dbSNP
rs1357122504 1986 dbSNP
rs1415075372 1986 dbSNP
rs982051798 1987 dbSNP
rs1275175666 1996 dbSNP
rs1447109246 1998 dbSNP
rs1355047738 2003 dbSNP
rs1330917767 2008 dbSNP
rs1464159273 2009 dbSNP
rs993730850 2012 dbSNP
rs1046690838 2035 dbSNP
rs1476342649 2037 dbSNP
rs62304300 2038 dbSNP
rs375358054 2039 dbSNP
rs1007970285 2062 dbSNP
rs1019822622 2062 dbSNP
rs749069924 2069 dbSNP
rs1332141984 2070 dbSNP
rs1233522962 2072 dbSNP
rs868766010 2073 dbSNP
rs1336493277 2076 dbSNP
rs775726571 2086 dbSNP
rs1310238776 2098 dbSNP
rs983415163 2099 dbSNP
rs1373912049 2100 dbSNP
rs996712122 2103 dbSNP
rs554525952 2104 dbSNP
rs1444533494 2114 dbSNP
rs1399625217 2117 dbSNP
rs907951973 2135 dbSNP
rs1256366180 2145 dbSNP
rs1463158132 2151 dbSNP
rs942101507 2154 dbSNP
rs1164470484 2158 dbSNP
rs1021480041 2159 dbSNP
rs1474054893 2169 dbSNP
rs968598920 2183 dbSNP
rs2868076 2184 dbSNP
rs1469213711 2189 dbSNP
rs924598694 2192 dbSNP
rs1156697383 2199 dbSNP
rs1489227823 2203 dbSNP
rs1263341449 2214 dbSNP
rs1387050359 2234 dbSNP
rs868074849 2244 dbSNP
rs992922138 2249 dbSNP
rs916003271 2261 dbSNP
rs1237862193 2262 dbSNP
rs1376081570 2263 dbSNP
rs540523369 2271 dbSNP
rs1052005620 2274 dbSNP
rs1365635535 2281 dbSNP
rs1293139924 2288 dbSNP
rs890699029 2289 dbSNP
rs554054890 2291 dbSNP
rs1347317370 2297 dbSNP
rs920768716 2301 dbSNP
rs184026863 2302 dbSNP
rs935002118 2303 dbSNP
rs1295380225 2304 dbSNP
rs1190257668 2305 dbSNP
rs1486028689 2316 dbSNP
rs190080571 2319 dbSNP
rs1214210007 2320 dbSNP
rs1352845911 2328 dbSNP
rs1238437053 2337 dbSNP
rs768957221 2342 dbSNP
rs1310507282 2344 dbSNP
rs893560640 2345 dbSNP
rs1300760684 2347 dbSNP
rs1382928461 2348 dbSNP
rs1353555076 2353 dbSNP
rs149377476 2357 dbSNP
rs531013234 2360 dbSNP
rs1280131826 2367 dbSNP
rs144715555 2372 dbSNP
rs1212530430 2374 dbSNP
rs899554176 2389 dbSNP
rs1176056775 2391 dbSNP
rs148511432 2392 dbSNP
rs1375425872 2403 dbSNP
rs59640859 2404 dbSNP
rs1179128136 2409 dbSNP
rs1365446882 2411 dbSNP
rs546845615 2415 dbSNP
rs1034940802 2421 dbSNP
rs114182936 2423 dbSNP
rs1191113173 2427 dbSNP
rs1004902804 2429 dbSNP
rs1014895209 2435 dbSNP
rs998773429 2436 dbSNP
rs1342785892 2441 dbSNP
rs1436377401 2442 dbSNP
rs1228278696 2445 dbSNP
rs568553505 2448 dbSNP
rs963695127 2451 dbSNP
rs1320225978 2456 dbSNP
rs973536615 2468 dbSNP
rs1314936945 2481 dbSNP
rs867365957 2490 dbSNP
rs1218307657 2496 dbSNP
rs1356491910 2497 dbSNP
rs1032042205 2499 dbSNP
rs1402136597 2502 dbSNP
rs114387529 2508 dbSNP
rs915932279 2514 dbSNP
rs1425209772 2518 dbSNP
rs953579876 2521 dbSNP
rs970077823 2531 dbSNP
rs1477328095 2538 dbSNP
rs987561952 2539 dbSNP
rs1189374418 2541 dbSNP
rs142750707 2543 dbSNP
rs1326999354 2547 dbSNP
rs1255430002 2549 dbSNP
rs72870296 2556 dbSNP
rs1459129861 2563 dbSNP
rs929515958 2569 dbSNP
rs1053103900 2571 dbSNP
rs537929453 2575 dbSNP
rs554308116 2577 dbSNP
rs866884292 2581 dbSNP
rs946374948 2585 dbSNP
rs1236979518 2586 dbSNP
rs1256217851 2589 dbSNP
rs1338406556 2594 dbSNP
rs1401835623 2601 dbSNP
rs879869446 2605 dbSNP
rs185593627 2611 dbSNP
rs772920730 2612 dbSNP
rs1464722643 2618 dbSNP
rs904911997 2626 dbSNP
rs1391025872 2628 dbSNP
rs1164742487 2629 dbSNP
rs1457846367 2633 dbSNP
rs1192873815 2637 dbSNP
rs1471672122 2639 dbSNP
rs1251076167 2641 dbSNP
rs1041086036 2644 dbSNP
rs1335007137 2647 dbSNP
rs1182424610 2651 dbSNP
rs1003378235 2654 dbSNP
rs932355575 2661 dbSNP
rs1198106601 2662 dbSNP
rs1174101394 2674 dbSNP
rs1469037614 2677 dbSNP
rs1056286161 2680 dbSNP
rs760316971 2687 dbSNP
rs534083631 2689 dbSNP
rs1356074114 2695 dbSNP
rs1261748085 2697 dbSNP
rs1242862911 2698 dbSNP
rs887034811 2702 dbSNP
rs1166200814 2709 dbSNP
rs1306388610 2710 dbSNP
rs776959280 2710 dbSNP
rs779820181 2710 dbSNP
rs377624145 2711 dbSNP
rs762887759 2715 dbSNP
rs1017245353 2719 dbSNP
rs1389745864 2725 dbSNP
rs1159031107 2727 dbSNP
rs1369440959 2728 dbSNP
rs1378430913 2730 dbSNP
rs1177980811 2731 dbSNP
rs1454746491 2732 dbSNP
rs1248586984 2733 dbSNP
rs1019859772 2739 dbSNP
rs1302466437 2744 dbSNP
rs1219270540 2746 dbSNP
rs963449576 2749 dbSNP
rs554068371 2756 dbSNP
rs1029086058 2757 dbSNP
rs1224737309 2759 dbSNP
rs374682244 2760 dbSNP
rs397977661 2760 dbSNP
rs59105562 2760 dbSNP
rs766228660 2762 dbSNP
rs953440810 2771 dbSNP
rs987613596 2772 dbSNP
rs1427275474 2776 dbSNP
rs1170905892 2777 dbSNP
rs1317923509 2778 dbSNP
rs973457504 2779 dbSNP
rs1196174572 2780 dbSNP
rs1212527041 2780 dbSNP
rs766253101 2782 dbSNP
rs956853491 2783 dbSNP
rs34144370 2789 dbSNP
rs1212225876 2796 dbSNP
rs866405651 2796 dbSNP
rs866844868 2797 dbSNP
rs1280059431 2799 dbSNP
rs950901327 2799 dbSNP
rs763126555 2800 dbSNP
rs983997616 2804 dbSNP
rs988453214 2807 dbSNP
rs777206770 2808 dbSNP
rs912081088 2808 dbSNP
rs944913082 2812 dbSNP
rs1426554214 2819 dbSNP
rs577133576 2829 dbSNP
rs1375019151 2833 dbSNP
rs946413205 2835 dbSNP
rs1477004198 2836 dbSNP
rs1466150292 2840 dbSNP
rs1045085789 2841 dbSNP
rs1474033053 2845 dbSNP
rs146281776 2854 dbSNP
rs751110027 2855 dbSNP
rs1042807522 2862 dbSNP
rs939051701 2863 dbSNP
rs1200063242 2867 dbSNP
rs1056212083 2870 dbSNP
rs886964281 2871 dbSNP
rs556308823 2882 dbSNP
rs1228702131 2883 dbSNP
rs1381117380 2884 dbSNP
rs1282338609 2888 dbSNP
rs1384637177 2890 dbSNP
rs1380897517 2893 dbSNP
rs1401121499 2894 dbSNP
rs1333454905 2906 dbSNP
rs1196429382 2911 dbSNP
rs1297193330 2914 dbSNP
rs58776991 2915 dbSNP
rs1038323516 2916 dbSNP
rs1165879908 2921 dbSNP
rs1425894444 2931 dbSNP
rs1412151466 2935 dbSNP
rs898372488 2936 dbSNP
rs994867812 2941 dbSNP
rs1238191686 2942 dbSNP
rs143272317 2942 dbSNP
rs1179992640 2943 dbSNP
rs1336818050 2947 dbSNP
rs1456141714 2948 dbSNP
rs1028922360 2949 dbSNP
rs544691279 2950 dbSNP
rs190599719 2951 dbSNP
rs1484739172 2959 dbSNP
rs181025769 2960 dbSNP
rs994827790 2964 dbSNP
rs1027626788 2968 dbSNP
rs540544199 2969 dbSNP
rs560383818 2974 dbSNP
rs532643623 2975 dbSNP
rs1444697167 2988 dbSNP
rs1376304785 2989 dbSNP
rs1022549877 2996 dbSNP
rs10007784 3001 dbSNP
rs1415713575 3008 dbSNP
rs1019496233 3009 dbSNP
rs77285094 3010 dbSNP
rs1420788410 3014 dbSNP
rs926303770 3015 dbSNP
rs974987263 3031 dbSNP
rs1452075310 3036 dbSNP
rs1157422607 3040 dbSNP
rs10019455 3041 dbSNP
rs1249270899 3049 dbSNP
rs1360742748 3051 dbSNP
rs548220710 3059 dbSNP
rs1244709838 3060 dbSNP
rs755472670 3064 dbSNP
rs534694930 3069 dbSNP
rs1221498030 3079 dbSNP
rs1354282287 3089 dbSNP
rs991946915 3090 dbSNP
rs908282229 3094 dbSNP
rs758997688 3117 dbSNP
rs1237933598 3121 dbSNP
rs1316408750 3130 dbSNP
rs1302077808 3134 dbSNP
rs1310728620 3142 dbSNP
rs939877209 3144 dbSNP
rs1388680608 3146 dbSNP
rs1365781655 3148 dbSNP
rs1356762942 3155 dbSNP
rs1400957732 3157 dbSNP
rs1038570619 3159 dbSNP
rs1306122379 3161 dbSNP
rs898425462 3174 dbSNP
rs1419696328 3187 dbSNP
rs1362650392 3188 dbSNP
rs1176176497 3196 dbSNP
rs185004282 3207 dbSNP
rs1434498235 3220 dbSNP
rs1422661660 3225 dbSNP
rs1240905580 3226 dbSNP
rs932589892 3234 dbSNP
rs1198290736 3251 dbSNP
rs780387780 3275 dbSNP
rs925645934 3281 dbSNP
rs747154791 3283 dbSNP
rs1049614471 3284 dbSNP
rs768600023 3288 dbSNP
rs1464116951 3294 dbSNP
rs760121001 3294 dbSNP
rs889156606 3295 dbSNP
rs1008847485 3297 dbSNP
rs1235550448 3298 dbSNP
rs1282856443 3309 dbSNP
rs1310555829 3309 dbSNP
rs1331009910 3310 dbSNP
rs767570873 3312 dbSNP
rs1342764908 3314 dbSNP
rs1296745012 3317 dbSNP
rs1018996680 3327 dbSNP
rs892508632 3330 dbSNP
rs1302878493 3333 dbSNP
rs1467104228 3337 dbSNP
rs752736710 3339 dbSNP
rs756279523 3344 dbSNP
rs1175248284 3350 dbSNP
rs781538715 3354 dbSNP
rs1182588254 3363 dbSNP
rs1425428586 3363 dbSNP
rs1009754597 3369 dbSNP
rs1022854355 3381 dbSNP
rs1417905313 3383 dbSNP
rs1191264411 3390 dbSNP
rs1427808468 3391 dbSNP
rs1256730071 3401 dbSNP
rs565375170 3408 dbSNP
rs377241503 3411 dbSNP
rs1033928640 3412 dbSNP
rs1262658471 3413 dbSNP
rs960394511 3418 dbSNP
rs1199436286 3419 dbSNP
rs991789761 3420 dbSNP
rs949911082 3426 dbSNP
rs908293681 3429 dbSNP
rs1227199414 3430 dbSNP
rs1341488248 3451 dbSNP
rs79024279 3462 dbSNP
rs547394541 3466 dbSNP
rs1394863088 3470 dbSNP
rs1360547049 3482 dbSNP
rs72870298 3487 dbSNP
rs1297164687 3490 dbSNP
rs188690032 3492 dbSNP
rs1371046485 3507 dbSNP
rs1306458261 3513 dbSNP
rs181254489 3515 dbSNP
rs1309909824 3517 dbSNP
rs1049012055 3524 dbSNP
rs1231809886 3526 dbSNP
rs886448920 3529 dbSNP
rs556129558 3534 dbSNP
rs1179366316 3542 dbSNP
rs1459230483 3542 dbSNP
rs1019067852 3551 dbSNP
rs1195495060 3570 dbSNP
rs1049668674 3573 dbSNP
rs1267676364 3583 dbSNP
rs1243178014 3587 dbSNP
rs996373093 3601 dbSNP
rs959712305 3611 dbSNP
rs1313684904 3612 dbSNP
rs530391692 3615 dbSNP
rs1378531991 3627 dbSNP
rs537960778 3640 dbSNP
rs1326425020 3655 dbSNP
rs1232415375 3659 dbSNP
rs1040331628 3663 dbSNP
rs1180999556 3664 dbSNP
rs979689694 3668 dbSNP
rs1384570918 3672 dbSNP
rs143831419 3672 dbSNP
rs33951934 3672 dbSNP
rs34076658 3672 dbSNP
rs66499257 3672 dbSNP
rs72366244 3672 dbSNP
rs752180944 3672 dbSNP
rs753153960 3672 dbSNP
rs201707777 3676 dbSNP
rs60461169 3681 dbSNP
rs1181358124 3683 dbSNP
rs1239336289 3683 dbSNP
rs925603197 3683 dbSNP
rs867921798 3685 dbSNP
rs1172239472 3686 dbSNP
rs988950363 3688 dbSNP
rs1010092302 3693 dbSNP
rs917034759 3695 dbSNP
rs1287341714 3701 dbSNP
rs1243022262 3702 dbSNP
rs868189452 3704 dbSNP
rs1414735381 3709 dbSNP
rs930526984 3716 dbSNP
rs1331353353 3717 dbSNP
rs1049004906 3720 dbSNP
rs1364788558 3721 dbSNP
rs770893094 3721 dbSNP
rs1298718762 3725 dbSNP
rs1352207571 3731 dbSNP
rs904056895 3741 dbSNP
rs1466742476 3744 dbSNP
rs555010746 3745 dbSNP
rs1002364878 3746 dbSNP
rs1004906795 3757 dbSNP
rs1331875119 3760 dbSNP
rs1478455001 3762 dbSNP
rs1033938494 3767 dbSNP
rs1370240091 3769 dbSNP
rs574517337 3772 dbSNP
rs1197085296 3777 dbSNP
rs960908407 3779 dbSNP
rs1040844142 3783 dbSNP
rs1013275198 3787 dbSNP
rs1487600423 3789 dbSNP
rs1281466378 3791 dbSNP
rs1015705220 3793 dbSNP
rs878954594 3795 dbSNP
rs1345166111 3802 dbSNP
rs961055401 3806 dbSNP
rs1369962506 3818 dbSNP
rs78222164 3826 dbSNP
rs919679047 3827 dbSNP
rs954023090 3828 dbSNP
rs985223111 3835 dbSNP
rs1029134234 3853 dbSNP
rs912500520 3857 dbSNP
rs1401705856 3858 dbSNP
rs1343395477 3859 dbSNP
rs1305783268 3867 dbSNP
rs1200609981 3871 dbSNP
rs943927321 3873 dbSNP
rs1415088254 3885 dbSNP
rs1468473636 3887 dbSNP
rs968242683 3891 dbSNP
rs774132212 3895 dbSNP
rs913913502 3897 dbSNP
rs185271763 3908 dbSNP
rs1248774781 3920 dbSNP
rs577161004 3924 dbSNP
rs1031277385 3931 dbSNP
rs955886072 3932 dbSNP
rs1242016958 3935 dbSNP
rs1442488048 3941 dbSNP
rs945392828 3957 dbSNP
rs988466511 3962 dbSNP
rs1185513715 3970 dbSNP
rs1044231989 3974 dbSNP
rs1478513380 3975 dbSNP
rs1359666295 3977 dbSNP
rs1024409824 3987 dbSNP
rs903901815 4000 dbSNP
rs971083441 4003 dbSNP
rs1002374980 4004 dbSNP
rs1469437644 4014 dbSNP
rs1401344766 4016 dbSNP
rs1173148520 4017 dbSNP
rs6857871 4022 dbSNP
rs896643717 4024 dbSNP
rs562944288 4025 dbSNP
rs1015845537 4033 dbSNP
rs191608057 4047 dbSNP
rs1460515836 4048 dbSNP
rs1258277276 4062 dbSNP
rs150986696 4074 dbSNP
rs1269756860 4079 dbSNP
rs1027154484 4081 dbSNP
rs953776411 4083 dbSNP
rs1358403946 4090 dbSNP
rs1338806639 4091 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 651.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714646. RNA binding protein: AGO2. Condition:mildMNase "PAR-CLIP data was present in GSM714647. RNA binding protein: AGO2. Condition:mildMNase ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ugacGUCGG--AAC--UGGAGGguc 5'
              |:|||   ||  ||||||   
Target 5' -ucuCGGCCCACUGCAACCUCCacc 3'
 		1 - 24
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions Prostate Tissue
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in SRX1760628. RNA binding protein: AGO2. Condition:AGO-CLIP-LAPC4_B ...

- Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al., 2016, Neoplasia (New York, N.Y.).

Article - Hamilton MP; Rajapakshe KI; Bader DA; Cerne et al.
- Neoplasia (New York, N.Y.), 2016
MicroRNA (miRNA) deregulation in prostate cancer (PCa) contributes to PCa initiation and metastatic progression. To comprehensively define the cancer-associated changes in miRNA targeting and function in commonly studied models of PCa, we performed photoactivatable ribonucleoside-enhanced cross-linking immunoprecipitation of the Argonaute protein in a panel of PCa cell lines modeling different stages of PCa progression. Using this comprehensive catalogue of miRNA targets, we analyzed miRNA targeting on known drivers of PCa and examined tissue-specific and stage-specific pathway targeting by miRNAs. We found that androgen receptor is the most frequently targeted PCa oncogene and that miR-148a targets the largest number of known PCa drivers. Globally, tissue-specific and stage-specific changes in miRNA targeting are driven by homeostatic response to active oncogenic pathways. Our findings indicate that, even in advanced PCa, the miRNA pool adapts to regulate continuing alterations in the cancer genome to balance oncogenic molecular changes. These findings are important because they are the first to globally characterize miRNA changes in PCa and demonstrate how the miRNA target spectrum responds to staged tumorigenesis.
LinkOut: [PMID: 27292025]
CLIP-seq Support 1 for dataset GSM714646
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repA
Location of target site ENST00000282701.2 | 3UTR | AUCUCGGCCCACUGCAACCUCCACCUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714647
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repB
Location of target site ENST00000282701.2 | 3UTR | UCUCGGCCCACUGCAACCUCCACC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
494 hsa-miR-1273h-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT074355 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT100721 TJAP1 tight junction associated protein 1 2 2
MIRT115545 MAZ MYC associated zinc finger protein 2 2
MIRT124982 XIAP X-linked inhibitor of apoptosis 2 4
MIRT139911 BTF3L4 basic transcription factor 3 like 4 2 6
MIRT177183 ARL5B ADP ribosylation factor like GTPase 5B 2 4
MIRT187994 MBD6 methyl-CpG binding domain protein 6 2 2
MIRT207410 MAT2A methionine adenosyltransferase 2A 2 6
MIRT241928 DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 2 2
MIRT260110 KLHL21 kelch like family member 21 2 2
MIRT260358 XRCC6 X-ray repair cross complementing 6 2 6
MIRT266428 RPRD2 regulation of nuclear pre-mRNA domain containing 2 2 2
MIRT294663 ZNF548 zinc finger protein 548 2 2
MIRT351039 PLEKHB2 pleckstrin homology domain containing B2 2 2
MIRT379943 PRRG4 proline rich and Gla domain 4 2 2
MIRT398983 KAT7 lysine acetyltransferase 7 2 2
MIRT441465 BEST3 bestrophin 3 2 2
MIRT446750 ZNF491 zinc finger protein 491 2 2
MIRT449224 RAD51B RAD51 paralog B 2 2
MIRT450623 AQR aquarius intron-binding spliceosomal factor 2 2
MIRT451090 ZNF584 zinc finger protein 584 2 2
MIRT451558 CIAPIN1 cytokine induced apoptosis inhibitor 1 2 2
MIRT451736 CES3 carboxylesterase 3 2 2
MIRT452411 QDPR quinoid dihydropteridine reductase 2 2
MIRT452559 ZFP69B ZFP69 zinc finger protein B 2 2
MIRT452851 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT452922 DISC1 disrupted in schizophrenia 1 2 2
MIRT453043 TANGO2 transport and golgi organization 2 homolog 2 4
MIRT453097 HOXC4 homeobox C4 2 2
MIRT453297 ZNF394 zinc finger protein 394 2 2
MIRT453593 ZNF557 zinc finger protein 557 2 2
MIRT453787 KBTBD12 kelch repeat and BTB domain containing 12 2 2
MIRT453987 CECR1 adenosine deaminase 2 2 2
MIRT454083 TMEM209 transmembrane protein 209 2 2
MIRT454652 FBXL18 F-box and leucine rich repeat protein 18 2 2
MIRT454753 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2 2
MIRT455311 TTLL9 tubulin tyrosine ligase like 9 2 2
MIRT456468 SERAC1 serine active site containing 1 2 2
MIRT456554 TOMM20 translocase of outer mitochondrial membrane 20 2 2
MIRT456716 TMEM239 transmembrane protein 239 2 4
MIRT456796 SIGLEC14 sialic acid binding Ig like lectin 14 2 2
MIRT457487 SLC35F6 solute carrier family 35 member F6 2 2
MIRT457999 MRPL12 mitochondrial ribosomal protein L12 2 2
MIRT458130 TLCD2 TLC domain containing 2 2 2
MIRT459027 ZNF490 zinc finger protein 490 2 4
MIRT459119 FADS6 fatty acid desaturase 6 2 2
MIRT459315 HAVCR2 hepatitis A virus cellular receptor 2 2 2
MIRT459385 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT459412 FAM83B family with sequence similarity 83 member B 2 2
MIRT459974 RFT1 RFT1 homolog 2 2
MIRT460480 FAM105A family with sequence similarity 105 member A 2 6
MIRT460586 FEM1A fem-1 homolog A 2 2
MIRT460920 NOA1 nitric oxide associated 1 2 4
MIRT461072 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT461590 DPH2 DPH2 homolog 2 2
MIRT461854 ZNF317 zinc finger protein 317 2 2
MIRT462176 ACADL acyl-CoA dehydrogenase, long chain 2 2
MIRT462446 GCDH glutaryl-CoA dehydrogenase 2 2
MIRT463854 WNT7B Wnt family member 7B 2 2
MIRT464310 UST uronyl 2-sulfotransferase 2 2
MIRT464815 UBE2B ubiquitin conjugating enzyme E2 B 2 2
MIRT465453 TOR2A torsin family 2 member A 2 2
MIRT466073 TMEM184C transmembrane protein 184C 2 2
MIRT466514 TBXA2R thromboxane A2 receptor 2 2
MIRT467072 SRRD SRR1 domain containing 2 2
MIRT469551 RARA retinoic acid receptor alpha 2 2
MIRT469741 RAB2B RAB2B, member RAS oncogene family 2 2
MIRT470759 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT470875 PLXND1 plexin D1 2 2
MIRT470976 PITPNA phosphatidylinositol transfer protein alpha 2 2
MIRT471048 PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2 2
MIRT471215 PHAX phosphorylated adaptor for RNA export 2 2
MIRT471246 PGM2L1 phosphoglucomutase 2 like 1 2 2
MIRT471286 PGAM4 phosphoglycerate mutase family member 4 2 2
MIRT471467 PDE7B phosphodiesterase 7B 2 2
MIRT473069 MORN4 MORN repeat containing 4 2 4
MIRT473989 LRRC20 leucine rich repeat containing 20 2 2
MIRT474518 KLHDC8A kelch domain containing 8A 2 2
MIRT474990 KANSL1 KAT8 regulatory NSL complex subunit 1 2 2
MIRT475547 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 2
MIRT476350 GIGYF1 GRB10 interacting GYF protein 1 2 2
MIRT477298 EPHB2 EPH receptor B2 2 2
MIRT477933 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory 2 2
MIRT478282 DDX19A DEAD-box helicase 19A 2 4
MIRT478472 CYP20A1 cytochrome P450 family 20 subfamily A member 1 2 2
MIRT478559 CTNND1 catenin delta 1 2 2
MIRT478618 CTDNEP1 CTD nuclear envelope phosphatase 1 2 2
MIRT478834 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT479007 COL5A1 collagen type V alpha 1 chain 2 2
MIRT479166 CLSPN claspin 2 2
MIRT482454 ADAR adenosine deaminase, RNA specific 2 4
MIRT483019 KHSRP KH-type splicing regulatory protein 2 4
MIRT483798 CYP2W1 cytochrome P450 family 2 subfamily W member 1 2 6
MIRT486087 SLC7A5 solute carrier family 7 member 5 2 4
MIRT486304 SIPA1 signal-induced proliferation-associated 1 2 2
MIRT486490 MYH11 myosin heavy chain 11 2 2
MIRT486881 TSPYL4 TSPY like 4 2 2
MIRT487125 NCOR2 nuclear receptor corepressor 2 2 2
MIRT487542 TM6SF2 transmembrane 6 superfamily member 2 2 4
MIRT487676 B3GALT5 beta-1,3-galactosyltransferase 5 2 4
MIRT489251 TTLL1 tubulin tyrosine ligase like 1 2 4
MIRT489276 RBM8A RNA binding motif protein 8A 2 8
MIRT489496 CRLF3 cytokine receptor like factor 3 2 4
MIRT489571 SSBP2 single stranded DNA binding protein 2 2 2
MIRT489694 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT490166 TMEM63C transmembrane protein 63C 2 2
MIRT491199 MLLT1 MLLT1, super elongation complex subunit 2 4
MIRT491260 DHX40 DEAH-box helicase 40 2 2
MIRT491385 HAUS3 HAUS augmin like complex subunit 3 2 2
MIRT491548 YAE1D1 Yae1 domain containing 1 2 2
MIRT492722 PHF12 PHD finger protein 12 2 2
MIRT493866 FAM73B mitoguardin 2 2 4
MIRT494549 BAK1 BCL2 antagonist/killer 1 2 2
MIRT498586 KRT8 keratin 8 2 2
MIRT498722 SNTN sentan, cilia apical structure protein 2 6
MIRT499982 HIST1H2BD histone cluster 1 H2B family member d 2 4
MIRT503414 SLC25A45 solute carrier family 25 member 45 2 6
MIRT508491 FTO FTO, alpha-ketoglutarate dependent dioxygenase 2 2
MIRT508877 METTL14 methyltransferase like 14 2 2
MIRT509622 RRP7A ribosomal RNA processing 7 homolog A 2 4
MIRT510104 IRAK3 interleukin 1 receptor associated kinase 3 2 8
MIRT510139 PDGFRA platelet derived growth factor receptor alpha 2 4
MIRT510353 ZNF703 zinc finger protein 703 2 6
MIRT510620 TMEM167A transmembrane protein 167A 2 4
MIRT510786 SF3B3 splicing factor 3b subunit 3 2 6
MIRT511021 NRF1 nuclear respiratory factor 1 2 2
MIRT513925 GHITM growth hormone inducible transmembrane protein 2 2
MIRT514342 DNAH17 dynein axonemal heavy chain 17 2 4
MIRT515015 SUMF2 sulfatase modifying factor 2 2 2
MIRT515246 DUSP28 dual specificity phosphatase 28 2 2
MIRT516202 RPP30 ribonuclease P/MRP subunit p30 2 2
MIRT516435 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT516666 ZNF860 zinc finger protein 860 2 4
MIRT518373 ZNF250 zinc finger protein 250 2 2
MIRT518930 LSG1 large 60S subunit nuclear export GTPase 1 2 2
MIRT519676 ZNF70 zinc finger protein 70 2 2
MIRT519902 ZFAND4 zinc finger AN1-type containing 4 2 4
MIRT519945 ZCCHC8 zinc finger CCHC-type containing 8 2 2
MIRT520321 UBXN2A UBX domain protein 2A 2 2
MIRT520606 TMEM41B transmembrane protein 41B 2 2
MIRT520663 TMEM11 transmembrane protein 11 2 2
MIRT520852 SUGT1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone 2 2
MIRT521443 RAD51 RAD51 recombinase 2 2
MIRT521671 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 2
MIRT522281 NKAP NFKB activating protein 2 2
MIRT522333 NCKIPSD NCK interacting protein with SH3 domain 2 8
MIRT522535 MED28 mediator complex subunit 28 2 6
MIRT523478 GNG4 G protein subunit gamma 4 2 2
MIRT523672 FOPNL FGFR1OP N-terminal like 2 2
MIRT523715 FBXW2 F-box and WD repeat domain containing 2 2 4
MIRT523867 ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 2 4
MIRT524043 DNAJC8 DnaJ heat shock protein family (Hsp40) member C8 2 2
MIRT524167 DFFA DNA fragmentation factor subunit alpha 2 2
MIRT524928 ALG10B ALG10B, alpha-1,2-glucosyltransferase 2 2
MIRT526825 PHC1 polyhomeotic homolog 1 2 2
MIRT531017 TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 2 2
MIRT536085 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT540681 BMP3 bone morphogenetic protein 3 2 2
MIRT541708 TMEM33 transmembrane protein 33 2 2
MIRT541755 KLF8 Kruppel like factor 8 2 2
MIRT541888 LY6G5B lymphocyte antigen 6 family member G5B 2 2
MIRT545714 SPTLC2 serine palmitoyltransferase long chain base subunit 2 2 2
MIRT559054 C19orf47 chromosome 19 open reading frame 47 2 4
MIRT561748 PLAGL2 PLAG1 like zinc finger 2 2 2
MIRT562365 ETV3 ETS variant 3 2 2
MIRT562821 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT562900 DNAH10OS dynein axonemal heavy chain 10 opposite strand 2 2
MIRT564452 SLC35E2 solute carrier family 35 member E2 2 5
MIRT569111 ONECUT3 one cut homeobox 3 2 2
MIRT569224 SUSD1 sushi domain containing 1 2 2
MIRT570271 ARPC3 actin related protein 2/3 complex subunit 3 2 2
MIRT570498 TFIP11 tuftelin interacting protein 11 2 2
MIRT570844 GPRC5C G protein-coupled receptor class C group 5 member C 2 2
MIRT571311 TPCN2 two pore segment channel 2 2 2
MIRT572077 EXOC8 exocyst complex component 8 2 2
MIRT572116 DNAJC24 DnaJ heat shock protein family (Hsp40) member C24 2 2
MIRT573054 TRIB1 tribbles pseudokinase 1 2 2
MIRT573483 IQSEC3 IQ motif and Sec7 domain 3 2 2
MIRT573656 HES6 hes family bHLH transcription factor 6 2 2
MIRT574343 ZBTB37 zinc finger and BTB domain containing 37 2 2
MIRT576494 Slc35e2 solute carrier family 35, member E2 2 4
MIRT608033 UBLCP1 ubiquitin like domain containing CTD phosphatase 1 2 2
MIRT611326 NANOS1 nanos C2HC-type zinc finger 1 2 2
MIRT613660 KIAA1210 KIAA1210 2 2
MIRT615638 ATF6 activating transcription factor 6 2 2
MIRT618573 RRAD RRAD, Ras related glycolysis inhibitor and calcium channel regulator 2 2
MIRT618865 MBL2 mannose binding lectin 2 2 2
MIRT618962 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT619172 SLC16A4 solute carrier family 16 member 4 2 2
MIRT620298 AQP6 aquaporin 6 2 2
MIRT620683 RFTN2 raftlin family member 2 2 2
MIRT621637 UBXN2B UBX domain protein 2B 2 2
MIRT621993 STK4 serine/threonine kinase 4 2 2
MIRT622421 NUDT19 nudix hydrolase 19 2 2
MIRT622804 PGAM5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase 2 4
MIRT624786 AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 2 2
MIRT624968 ZNF665 zinc finger protein 665 2 4
MIRT625479 SMAD9 SMAD family member 9 2 2
MIRT626594 ACAA2 acetyl-CoA acyltransferase 2 2 4
MIRT626708 TRIM65 tripartite motif containing 65 2 2
MIRT626975 LINC00598 long intergenic non-protein coding RNA 598 2 2
MIRT627489 STRIP2 striatin interacting protein 2 2 2
MIRT628505 ZNF878 zinc finger protein 878 2 2
MIRT628533 ZNF701 zinc finger protein 701 2 2
MIRT628591 TMEM251 transmembrane protein 251 2 2
MIRT628818 SLC25A34 solute carrier family 25 member 34 2 2
MIRT628896 IGSF6 immunoglobulin superfamily member 6 2 2
MIRT628958 UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative) 2 2
MIRT629005 OSBPL10 oxysterol binding protein like 10 2 2
MIRT629059 KIF1C kinesin family member 1C 2 2
MIRT629192 PAPOLA poly(A) polymerase alpha 2 2
MIRT629346 TMPRSS11BNL TMPRSS11B N-terminal like, pseudogene 2 2
MIRT629447 WIZ widely interspaced zinc finger motifs 2 2
MIRT629696 XKR4 XK related 4 2 2
MIRT629737 SCD5 stearoyl-CoA desaturase 5 2 2
MIRT629896 SPATA5 spermatogenesis associated 5 2 2
MIRT629953 GLP2R glucagon like peptide 2 receptor 2 2
MIRT630023 MTL5 testis expressed metallothionein like protein 2 2
MIRT630181 TLN1 talin 1 2 2
MIRT630325 PAQR5 progestin and adipoQ receptor family member 5 2 2
MIRT630389 MYH9 myosin heavy chain 9 2 4
MIRT630695 EXTL3 exostosin like glycosyltransferase 3 2 2
MIRT631054 LINC00346 long intergenic non-protein coding RNA 346 2 2
MIRT631130 SYNJ2 synaptojanin 2 2 2
MIRT631374 COL4A3BP collagen type IV alpha 3 binding protein 2 2
MIRT631557 TRAF3IP2 TRAF3 interacting protein 2 2 2
MIRT631615 PCDHB11 protocadherin beta 11 2 2
MIRT631935 CDKAL1 CDK5 regulatory subunit associated protein 1 like 1 2 4
MIRT632109 SSR1 signal sequence receptor subunit 1 2 2
MIRT632168 CCL22 C-C motif chemokine ligand 22 2 2
MIRT632445 SGTB small glutamine rich tetratricopeptide repeat containing beta 2 2
MIRT632652 NAV1 neuron navigator 1 2 2
MIRT632688 MTMR10 myotubularin related protein 10 2 2
MIRT632828 IGF1 insulin like growth factor 1 2 2
MIRT632905 FRRS1 ferric chelate reductase 1 2 2
MIRT633027 DNAL1 dynein axonemal light chain 1 2 2
MIRT633379 FBXW8 F-box and WD repeat domain containing 8 2 2
MIRT633440 KLLN killin, p53-regulated DNA replication inhibitor 2 2
MIRT633726 BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2 2
MIRT633832 WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 2 2
MIRT633862 ATP6V1A ATPase H+ transporting V1 subunit A 2 2
MIRT634042 NUP155 nucleoporin 155 2 2
MIRT634266 TIAL1 TIA1 cytotoxic granule associated RNA binding protein like 1 2 2
MIRT634374 RAP2B RAP2B, member of RAS oncogene family 2 2
MIRT634439 PDE7A phosphodiesterase 7A 2 2
MIRT634573 LRIG2 leucine rich repeats and immunoglobulin like domains 2 2 2
MIRT634620 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT634693 DSEL dermatan sulfate epimerase-like 2 2
MIRT634768 CD3D CD3d molecule 2 2
MIRT635024 WWTR1 WW domain containing transcription regulator 1 2 2
MIRT635384 NHLRC2 NHL repeat containing 2 2 2
MIRT635577 TTC9C tetratricopeptide repeat domain 9C 2 2
MIRT635793 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT635837 ZNF264 zinc finger protein 264 2 2
MIRT636043 ZSCAN29 zinc finger and SCAN domain containing 29 2 4
MIRT636070 ZNF280C zinc finger protein 280C 2 2
MIRT636697 ARSK arylsulfatase family member K 2 2
MIRT637438 ZNF324B zinc finger protein 324B 2 2
MIRT637582 PLD6 phospholipase D family member 6 2 2
MIRT637672 PPM1D protein phosphatase, Mg2+/Mn2+ dependent 1D 2 2
MIRT637887 SLC19A3 solute carrier family 19 member 3 2 4
MIRT638353 RBMS2 RNA binding motif single stranded interacting protein 2 2 4
MIRT638597 HINT1 histidine triad nucleotide binding protein 1 2 2
MIRT638821 CRTAP cartilage associated protein 2 2
MIRT638871 CEP97 centrosomal protein 97 2 4
MIRT639660 PPEF2 protein phosphatase with EF-hand domain 2 2 4
MIRT640200 TIMM50 translocase of inner mitochondrial membrane 50 2 2
MIRT641592 TNS4 tensin 4 2 2
MIRT644993 POLR2J3 RNA polymerase II subunit J3 2 2
MIRT645059 UQCRQ ubiquinol-cytochrome c reductase complex III subunit VII 2 2
MIRT646948 UPK3BL uroplakin 3B like 1 2 2
MIRT647306 RPH3AL rabphilin 3A like (without C2 domains) 2 2
MIRT648300 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 4
MIRT649043 SLC1A2 solute carrier family 1 member 2 2 2
MIRT649884 SLFN12L schlafen family member 12 like 2 2
MIRT650196 DOCK7 dedicator of cytokinesis 7 2 2
MIRT654789 PRICKLE1 prickle planar cell polarity protein 1 2 2
MIRT655667 NUP43 nucleoporin 43 2 2
MIRT655925 NDUFA4P1 NDUFA4, mitochondrial complex associated pseudogene 1 2 2
MIRT656433 MARCH6 membrane associated ring-CH-type finger 6 2 2
MIRT657713 GPC4 glypican 4 2 2
MIRT659302 CSTF1 cleavage stimulation factor subunit 1 2 2
MIRT659844 CAPZB capping actin protein of muscle Z-line beta subunit 2 2
MIRT660660 ANKFY1 ankyrin repeat and FYVE domain containing 1 2 2
MIRT661308 CPM carboxypeptidase M 2 2
MIRT661473 CHMP1B charged multivesicular body protein 1B 2 2
MIRT661906 EBNA1BP2 EBNA1 binding protein 2 2 2
MIRT662064 ZNF284 zinc finger protein 284 2 2
MIRT662491 ANGPT4 angiopoietin 4 2 2
MIRT662657 LRRC47 leucine rich repeat containing 47 2 2
MIRT662804 MSRB2 methionine sulfoxide reductase B2 2 2
MIRT663164 FGFR1OP FGFR1 oncogene partner 2 2
MIRT663376 ZNF770 zinc finger protein 770 2 4
MIRT663418 ZNF607 zinc finger protein 607 2 2
MIRT663990 WDR75 WD repeat domain 75 2 2
MIRT664157 APOBEC3F apolipoprotein B mRNA editing enzyme catalytic subunit 3F 2 4
MIRT664489 POLR3K RNA polymerase III subunit K 2 2
MIRT665058 CCDC77 coiled-coil domain containing 77 2 2
MIRT665080 CRIPT CXXC repeat containing interactor of PDZ3 domain 2 2
MIRT665420 WDR55 WD repeat domain 55 2 2
MIRT665716 TMTC1 transmembrane and tetratricopeptide repeat containing 1 2 2
MIRT665923 TBC1D19 TBC1 domain family member 19 2 4
MIRT666239 SLC38A7 solute carrier family 38 member 7 2 4
MIRT666840 PPTC7 PTC7 protein phosphatase homolog 2 2
MIRT667378 MOB1B MOB kinase activator 1B 2 2
MIRT667573 LONRF2 LON peptidase N-terminal domain and ring finger 2 2 2
MIRT667894 ING1 inhibitor of growth family member 1 2 2
MIRT667977 HECTD3 HECT domain E3 ubiquitin protein ligase 3 2 2
MIRT668197 GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2 2
MIRT668279 FOSL2 FOS like 2, AP-1 transcription factor subunit 2 2
MIRT668386 FAT3 FAT atypical cadherin 3 2 2
MIRT668444 FAM208A family with sequence similarity 208 member A 2 2
MIRT668998 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT669180 CCNF cyclin F 2 2
MIRT669444 ATL3 atlastin GTPase 3 2 2
MIRT669661 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2 2
MIRT669890 KIAA0754 KIAA0754 2 4
MIRT669973 SSR3 signal sequence receptor subunit 3 2 2
MIRT670153 SLC29A4 solute carrier family 29 member 4 2 2
MIRT670240 TRIM13 tripartite motif containing 13 2 2
MIRT670274 CBY3 chibby family member 3 2 2
MIRT670358 ULBP3 UL16 binding protein 3 2 4
MIRT670627 BVES blood vessel epicardial substance 2 2
MIRT670731 HOOK3 hook microtubule tethering protein 3 2 2
MIRT670770 TRIM66 tripartite motif containing 66 2 2
MIRT670913 DESI1 desumoylating isopeptidase 1 2 2
MIRT671216 CLSTN1 calsyntenin 1 2 2
MIRT671398 ERCC6L2 ERCC excision repair 6 like 2 2 2
MIRT671427 TOX4 TOX high mobility group box family member 4 2 2
MIRT671654 TRUB2 TruB pseudouridine synthase family member 2 2 4
MIRT671702 PMPCA peptidase, mitochondrial processing alpha subunit 2 2
MIRT672136 PLEKHH1 pleckstrin homology, MyTH4 and FERM domain containing H1 2 2
MIRT672395 SLC10A6 solute carrier family 10 member 6 2 2
MIRT672508 GGCX gamma-glutamyl carboxylase 2 2
MIRT672572 RNF24 ring finger protein 24 2 2
MIRT672789 PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L 2 2
MIRT673019 RBBP4 RB binding protein 4, chromatin remodeling factor 2 2
MIRT673190 C10orf76 chromosome 10 open reading frame 76 2 2
MIRT673372 ZNF124 zinc finger protein 124 2 2
MIRT673495 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 6
MIRT673852 CAPN7 calpain 7 2 2
MIRT673929 ZNF500 zinc finger protein 500 2 2
MIRT673986 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT674076 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT674123 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT674297 THAP5 THAP domain containing 5 2 2
MIRT674370 POLR3D RNA polymerase III subunit D 2 2
MIRT674641 NKRF NFKB repressing factor 2 2
MIRT674665 PLCE1 phospholipase C epsilon 1 2 2
MIRT674725 ZNF451 zinc finger protein 451 2 4
MIRT674779 NPR1 natriuretic peptide receptor 1 2 2
MIRT674889 RASSF9 Ras association domain family member 9 2 2
MIRT675017 SNX1 sorting nexin 1 2 2
MIRT675341 KLHL26 kelch like family member 26 2 2
MIRT675416 CLEC7A C-type lectin domain containing 7A 2 2
MIRT675497 HSD17B12 hydroxysteroid 17-beta dehydrogenase 12 2 2
MIRT675615 EHD2 EH domain containing 2 2 2
MIRT675735 AHR aryl hydrocarbon receptor 2 2
MIRT675857 ATP1B4 ATPase Na+/K+ transporting family member beta 4 2 2
MIRT675990 CRKL CRK like proto-oncogene, adaptor protein 2 2
MIRT676213 TMEM91 transmembrane protein 91 2 2
MIRT676406 MRO maestro 2 2
MIRT677299 CPSF2 cleavage and polyadenylation specific factor 2 2 2
MIRT677387 PCNP PEST proteolytic signal containing nuclear protein 2 2
MIRT677859 ABI2 abl interactor 2 2 2
MIRT677965 ITGB3 integrin subunit beta 3 2 2
MIRT678175 CRCP CGRP receptor component 2 2
MIRT678273 PTRH2 peptidyl-tRNA hydrolase 2 2 2
MIRT678665 SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 2 2
MIRT679003 TTC39B tetratricopeptide repeat domain 39B 2 2
MIRT679053 RMDN1 regulator of microtubule dynamics 1 2 2
MIRT679461 RHOF ras homolog family member F, filopodia associated 2 2
MIRT679513 RAB36 RAB36, member RAS oncogene family 2 2
MIRT679914 ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2 2
MIRT680029 OSBPL2 oxysterol binding protein like 2 2 4
MIRT680245 NDUFA7 NADH:ubiquinone oxidoreductase subunit A7 2 2
MIRT680279 AKIP1 A-kinase interacting protein 1 2 2
MIRT680499 PRIM2 DNA primase subunit 2 2 2
MIRT680586 ZNF573 zinc finger protein 573 2 2
MIRT680629 KIAA1456 KIAA1456 2 2
MIRT680819 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT680998 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT681122 INTS7 integrator complex subunit 7 2 2
MIRT681161 IBA57 IBA57 homolog, iron-sulfur cluster assembly 2 2
MIRT681221 DUSP19 dual specificity phosphatase 19 2 2
MIRT681304 IKZF3 IKAROS family zinc finger 3 2 2
MIRT681341 BRI3BP BRI3 binding protein 2 2
MIRT681608 F2RL2 coagulation factor II thrombin receptor like 2 2 2
MIRT681779 EIF4A3 eukaryotic translation initiation factor 4A3 2 2
MIRT681892 SLC11A2 solute carrier family 11 member 2 2 2
MIRT682084 ITGA3 integrin subunit alpha 3 2 4
MIRT682139 SMS spermine synthase 2 2
MIRT682217 SAR1A secretion associated Ras related GTPase 1A 2 2
MIRT682367 PHACTR4 phosphatase and actin regulator 4 2 2
MIRT682535 EXOSC2 exosome component 2 2 2
MIRT682618 COX6B1 cytochrome c oxidase subunit 6B1 2 2
MIRT683643 ZNF695 zinc finger protein 695 2 2
MIRT684008 FOLR1 folate receptor 1 2 2
MIRT684442 MFSD4 major facilitator superfamily domain containing 4A 2 2
MIRT684855 ZNF749 zinc finger protein 749 2 2
MIRT684956 MINOS1 mitochondrial inner membrane organizing system 1 2 2
MIRT685044 GEMIN4 gem nuclear organelle associated protein 4 2 2
MIRT685095 DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 2 2
MIRT685382 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT685456 CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 2 2
MIRT685810 SLC27A1 solute carrier family 27 member 1 2 2
MIRT685913 MOCS3 molybdenum cofactor synthesis 3 2 2
MIRT686665 TMEM120B transmembrane protein 120B 2 2
MIRT686955 SFT2D2 SFT2 domain containing 2 2 2
MIRT687118 QPCTL glutaminyl-peptide cyclotransferase like 2 2
MIRT687739 KIAA1328 KIAA1328 2 2
MIRT688063 GLUL glutamate-ammonia ligase 2 2
MIRT688191 FNIP1 folliculin interacting protein 1 2 2
MIRT688769 CDH7 cadherin 7 2 2
MIRT688979 ATP6AP1 ATPase H+ transporting accessory protein 1 2 2
MIRT689572 NUDT7 nudix hydrolase 7 2 2
MIRT689683 TMPRSS12 transmembrane protease, serine 12 2 2
MIRT689930 MANSC1 MANSC domain containing 1 2 2
MIRT690089 PNMA2 paraneoplastic Ma antigen 2 2 2
MIRT690190 C5orf45 MRN complex interacting protein 2 2
MIRT690246 CAMLG calcium modulating ligand 2 2
MIRT690411 FAM71F2 family with sequence similarity 71 member F2 2 2
MIRT690840 DSN1 DSN1 homolog, MIS12 kinetochore complex component 2 2
MIRT690889 FUT2 fucosyltransferase 2 2 2
MIRT691107 ADIPOQ adiponectin, C1Q and collagen domain containing 2 2
MIRT691229 DFNB59 pejvakin 2 2
MIRT691300 ZNF681 zinc finger protein 681 2 2
MIRT691366 GP5 glycoprotein V platelet 2 2
MIRT691797 WARS tryptophanyl-tRNA synthetase 2 2
MIRT692142 CEP104 centrosomal protein 104 2 2
MIRT692572 NCMAP non-compact myelin associated protein 2 2
MIRT692649 ZMYM1 zinc finger MYM-type containing 1 2 2
MIRT692744 NDUFS5 NADH:ubiquinone oxidoreductase subunit S5 2 2
MIRT693092 SCNM1 sodium channel modifier 1 2 2
MIRT693296 SYTL3 synaptotagmin like 3 2 2
MIRT693392 ZNF460 zinc finger protein 460 2 2
MIRT693530 ZNF708 zinc finger protein 708 2 2
MIRT693562 PIGR polymeric immunoglobulin receptor 2 2
MIRT694492 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT694722 LLGL1 LLGL1, scribble cell polarity complex component 2 2
MIRT694866 ZNF417 zinc finger protein 417 2 2
MIRT695070 ZNF17 zinc finger protein 17 2 2
MIRT695451 COX18 COX18, cytochrome c oxidase assembly factor 2 2
MIRT695724 ZNF117 zinc finger protein 117 2 2
MIRT695898 MED16 mediator complex subunit 16 2 2
MIRT696244 UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 2 2
MIRT696259 TACO1 translational activator of cytochrome c oxidase I 2 2
MIRT696512 C3 complement C3 2 2
MIRT696560 TTC21B tetratricopeptide repeat domain 21B 2 2
MIRT696643 AGXT2 alanine--glyoxylate aminotransferase 2 2 2
MIRT696791 DHODH dihydroorotate dehydrogenase (quinone) 2 2
MIRT696819 PLLP plasmolipin 2 2
MIRT697088 GPKOW G-patch domain and KOW motifs 2 2
MIRT697153 INMT indolethylamine N-methyltransferase 2 2
MIRT697202 ZYG11A zyg-11 family member A, cell cycle regulator 2 2
MIRT697322 ZNF641 zinc finger protein 641 2 2
MIRT697578 YME1L1 YME1 like 1 ATPase 2 2
MIRT697619 WSB1 WD repeat and SOCS box containing 1 2 2
MIRT698619 TES testin LIM domain protein 2 2
MIRT698804 STK38 serine/threonine kinase 38 2 2
MIRT698949 SPAST spastin 2 2
MIRT699083 SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 2 2
MIRT699430 SLC1A5 solute carrier family 1 member 5 2 2
MIRT699550 SIT1 signaling threshold regulating transmembrane adaptor 1 2 2
MIRT700324 RAB4A RAB4A, member RAS oncogene family 2 2
MIRT700360 RAB33B RAB33B, member RAS oncogene family 2 2
MIRT700462 PURB purine rich element binding protein B 2 2
MIRT701677 MYADM myeloid associated differentiation marker 2 2
MIRT701757 MSL2 MSL complex subunit 2 2 2
MIRT701977 MIER3 MIER family member 3 2 2
MIRT703178 GPBP1 GC-rich promoter binding protein 1 2 2
MIRT703203 GOLGA3 golgin A3 2 2
MIRT703359 GAPVD1 GTPase activating protein and VPS9 domains 1 2 2
MIRT703425 FYTTD1 forty-two-three domain containing 1 2 2
MIRT703484 FNDC3B fibronectin type III domain containing 3B 2 2
MIRT703590 FBXO45 F-box protein 45 2 2
MIRT703806 EVI5 ecotropic viral integration site 5 2 2
MIRT703915 EPG5 ectopic P-granules autophagy protein 5 homolog 2 2
MIRT704234 DHDDS dehydrodolichyl diphosphate synthase subunit 2 2
MIRT704646 CLCC1 chloride channel CLIC like 1 2 2
MIRT705151 C11orf58 chromosome 11 open reading frame 58 2 2
MIRT705480 ASXL2 additional sex combs like 2, transcriptional regulator 2 2
MIRT705530 ARL10 ADP ribosylation factor like GTPase 10 2 2
MIRT705661 ANKRD40 ankyrin repeat domain 40 2 2
MIRT706144 ZNF674 zinc finger protein 674 2 2
MIRT706473 SNX27 sorting nexin family member 27 2 2
MIRT708254 PGPEP1 pyroglutamyl-peptidase I 2 2
MIRT708838 SCAND3 zinc finger BED-type containing 9 1 1
MIRT710437 BTNL3 butyrophilin like 3 2 2
MIRT711325 DPYSL5 dihydropyrimidinase like 5 2 2
MIRT716151 RBM48 RNA binding motif protein 48 2 2
MIRT717402 ZCCHC24 zinc finger CCHC-type containing 24 2 2
MIRT720866 ADCY5 adenylate cyclase 5 2 2
MIRT722226 ZNF503 zinc finger protein 503 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-1273h-5p Paclitaxel 36314 NSC125973 approved sensitive High Ovarian Cancer cell line (SKOV3)
hsa-miR-1273h-5p Tripterygium wilfordii Hook F resistant tissue
hsa-miR-1273h-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (MGC-803)

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