miRTarBase - #MIRT541793


—
pre-miRNA Information
pre-miRNA hsa-mir-6511b-1   
Genomic Coordinates chr16: 2106669 - 2106753
Description Homo sapiens miR-6511b-1 stem-loop
Comment None
RNA Secondary Structure
pre-miRNA hsa-mir-6511b-2   
Genomic Coordinates chr16: 15134075 - 15134145
Description Homo sapiens miR-6511b-2 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-6511b-3p
Sequence 53| CCUCACCACCCCUUCUGCCUGCA |75
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
993639 5 ClinVar
1196654 15 ClinVar
256998 15 ClinVar
433980 16 ClinVar
586295 18 ClinVar
433979 19 ClinVar
COSM3948368 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs769351879 1 dbSNP
rs1001283562 2 dbSNP
rs763611191 3 dbSNP
rs1465530682 4 dbSNP
rs1227492873 4 dbSNP
rs745502224 5 dbSNP
rs551972801 6 dbSNP
rs538162642 6 dbSNP
rs751438298 7 dbSNP
rs1285683081 7 dbSNP
rs1340898267 8 dbSNP
rs4018164 9 dbSNP
rs370568831 9 dbSNP
rs1180919709 10 dbSNP
rs1339482497 10 dbSNP
rs758216756 11 dbSNP
rs1323026290 11 dbSNP
rs1239445091 12 dbSNP
rs1310601001 12 dbSNP
rs1431093969 13 dbSNP
rs752690118 15 dbSNP
rs1371790714 15 dbSNP
rs746463189 16 dbSNP
rs1209415208 17 dbSNP
rs761022804 17 dbSNP
rs1242038386 17 dbSNP
rs370411414 18 dbSNP
rs759723934 19 dbSNP
rs1428318191 19 dbSNP
rs1416441031 20 dbSNP
rs754040914 21 dbSNP
rs776062795 21 dbSNP
rs1273686335 22 dbSNP
rs1182772456 22 dbSNP
rs1472619959 23 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol MGAT5   
Synonyms GNT-V, GNT-VA
Description mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
Transcript NM_002410   
Expression
Putative miRNA Targets on MGAT5
3'UTR of MGAT5
(miRNA target sites are highlighted)		 
>MGAT5|NM_002410|3'UTR
   1 CAGCTACCTGCTCAGCCCTGCACCATGCTGCTGGGGAAGACAGTGGCCCCAGCCCCGTCAGGCAGGGCCAGGGACAGAAG
  81 TCATGCAGGGACTCTGGCAAGAGCCTGAACTTTTTCGTAGAAGGTTCTGAATTGGCATTGCCCTTGCTGCACTCCGAGCA
 161 ACCCAGTGGAGTCTTCACCAAAACAAAACAAGAGCGTATGTCAGGCCAGGAGCCTGGCTTGTCCCTGGCACAACATCATT
 241 TCTGTTTCTCAAGGAGCAACTGTGGGAAGACTGTCACTGCAGCTGCTCCAGGGCAAAAGAAAGTCTCAAGAGTCCTTTAA
 321 AACAAAACAGGAGGAATTGAGCTGATGGGAAAGAACTCTGAATGGGAATATTCCTAAACCCATTAACTTATTTATTCGGG
 401 TGGGAGGGAGGGGACCGCGGGAGGGAGAGGAGGGATTGATCACAGGCTTCTTTTATTTCCACTGTTAATCATCCACCTTC
 481 ACTATACTGTTGTTCTGTCTGCTTTGGGCAGGGTGCAGGAGAGAGACCGTGTGCCGTGGGGCTGGTGGCCTGCTCAGGGA
 561 CAGCCATGGGGACCTGGCAGCTCAAAACAGATGGCAGCAGAACAAAAGAAACTTTTGCTTTGGAAGCACAGCCAAACTCC
 641 CCAGGGCATCGTCATAGATGGCACCTAGAGCATGGGCTGCCTCAGTCAGGGGGACGTGCCTGTGTTGTCCAGAGAGCCCA
 721 GCCAGGGACGAAAAAGGAGATGAGGCCCCTTTCCTCCATGTCCCCATGCCCAGACACATACCTTGGCCGTAATTTCTTTT
 801 AGAATCCCTTTGGGAAGGAAATACAGGATTGAGGGATTTTGGAGTTTCTGGTAAACTCACCCTCCCTCCAGCCCCGCTAT
 881 GAGGAGGAAAGTAGAGATGAAAGACTCACGCTGTTCATGGACTTGGAGAGGATTATCTTTGAGCCAAGATTTGGACAGGA
 961 GTGAAGTCGGTCCTTAAGAATTTGTGGCGCGACCGGAGCTGGGCTCCTGACAGGTGGGCTTGTGTTGTGTCCCCTCTGAT
1041 GGCACCAAAGTCCAGGGAAGGGGGCTCTTGATGTCTGCTGGGGGAGTGGGGGCAGCTCAGGATGAATGCAGTGCCCTGTC
1121 CTGGCTACTCACCTGAGGGTGTAGCTCGCAAAGGTGGGAATCTGGTGCTGGCTTTTCCTTCAGGCAGGATCACTCTGACT
1201 TGTTGAGTAATCAGTCATCAGGTTGGCCTGGTCAGACACACTGGACCCCACCTTCCAAACCCTGGACCCCCCCATGCTCT
1281 GCCTTTGTATAAGTTCCCACCCCACTGAATCATTGCTGCCATGCTCTGTACAAGTTTGTAAGTTTCTGAAAAGCCCCTGA
1361 CATCTCCATGCTGATGCAAGTGAGACCCCTTCTGCCTAATGTGAGCGGTTGGCGTCCTCCACTTGGCCTCTGCTGGGCGC
1441 CTCAGTCGCTCAATGATGTGCTCTGTGCCGGGGCTTCCAAGCACCCTTCCTGCTAACAGAGGGCGGCCCAGTGGAGCCTC
1521 CGCTGGGCAGAACTGATGGGCAAGGCGTAATGGCTGGTAGCTTTCAGAATGTGAGGGAAAGGAAGAATTCCGCTTCATGG
1601 GGACTAGAGTTAGTGTGGGGCCTTTAAGTCTGGGAAGTTACATTCTGCTTCTTTCTCAATTGCTACACAAATGTGCAGCC
1681 AGCCTTTTTTCTTAGGCCCACTGAGATCCCTGCTCAGTGCGTCTCAATTGTATCTCCAGTCTAAGAGGAGGGTGGGGGGC
1761 ACCCGGGGCCTCCTCCACTCCTTAGGTGGCCCCCAAGCACATCTGCCAGGTAGAGTACCATGGGGAGGCCTCTGCCCTGA
1841 GCATCATCACAGGGGCGCCTCCAGACCTGGCTGAGAATAGCCTCTGCTTGGGCCTAGGAAGAAGGGCAGAAGTCCAAAGG
1921 AAACCTTGGTGAGTGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGAGCCTGTGCATTT
2001 CTTTTAAGCAAGGGCAGTTTCCTGCAGTAGGAGGGCAGATGACTGGCATCCTTGCTGTAAGGAAGAGCTTTTTCCTTGTG
2081 AATGGGCCTCTTGGCTGTACCCTAGGGTGTGGGAATTTGCTAGAGTTCCCTGACCTGCAATCCCTGGGCCAGTGCCGCCC
2161 TCTCCTGGGCTCTTCCAGGAGCATTGAACACTGAGGATGTCAATGCAAGTATCTGACCAACAGGGGGAGCCTGCAGGCCG
2241 AGCAAAGTTTAACCCACTTAGCCACTGCTACTTAAGCAAGGAAGCTGAAAGGTAACCTTAGCCCTGCCTTGTGTTCCAAA
2321 AGCTGCAAGGATCATTTGCTGGCTGTCCCTAAGTTCAAGGCCTCCCTACCTTCCCCTTCTTTTCCAAGTCACAACCCGCC
2401 CTGCCCGGGCCAGACAGCCCAGAAGAACACTTTTCTGCCATTTAAAAATCCCTCTTTCATCCCCCCCAGTCCAGTATTGA
2481 GTGGAAGTGCGCCGGAGTTCCACTGACAGGGCAGCTGCTCTTGGAGCAAACAAGCCCACACTCCAGTTGTTTAGGGCATT
2561 ATCTGAAGAGTCAGTGACCCCTGAATGTGTACTGGCTCCCAGGCCTCCTCAGACTTGGCCCAGGTCTAGTCAGTGATCCT
2641 GGAGAGGAAACTGGGGAGGGGGCTTCCAACTGCCCTGCATGGAAGAGGAGAGGAAGGTGCCCCTGTGTGGGCTGGAAGCC
2721 TGCGGAGGTTTTGCCATTGCTGATCTTGATAGAATCCTAAACCGATTTATAGCTGATAACAGTTCCATGGGGAGAGAAAT
2801 CCTAAGTTATGATTAATGTTTTTCCCCGCTATAATATCTTGCCTGTTTTTTTGGATTATTTTCCCCATTGTGATCCTAAG
2881 CTCTTAAAAAACTTGAGGGAAAACATTCATCTAATTTACTAAAAGAGAAAGCTTTCCATTGAAAGGTAGATACTTTGAGG
2961 AGTAAAAAGACTTCTTTGAATGCTGGTAAACACCGCATTTATTTTGTGTATGCAGTTTGATTTGCACATGTATAAATGGA
3041 GATGCTTTTCATTTTTGTTTGGACTGGGTTTGTGTCACTGCTCATTACAGTTTGCTTTTTTGTGTGTTTGCTGTGCGTTT
3121 GGAGATATTAGTCAGTTTCTTTAGTGATATTTGTTTCCTTGATGTGCCTTTTCGTTTTTCTTTGGGGTTTTTGGAATCCG
3201 GATGCTGTTGAAGGGCAATAGCAGACTCCTCCAGCTAAGAGACAGGACATGTTCTTGAGCCACTGTAGCTGTTGAAGCTG
3281 GACACCAGACGCTCCCTATAACCCCCCCGCCAGGCCATAGCGTGTATGCATGTGCACTTCCACCCACAGAGGAGGGTGTG
3361 AAGCCTTGAGAACCTCAAGAAAGGGCTGGATTCTGCCATACCTTTGGGTCTACCTTGGGACTGCTGGTTGCCAACGTGTC
3441 AACCAGCCTGTGTTCCCTGCCACCCACGCACTTGCTGAGGTGTGGCTGAGGCAGAATCATGTGAATGGGTGCATCCAAGG
3521 AGTTCAGGGCCCTGCTTGGAGAAGAAATACTTTAGCATCATGAAAGGGAAAGAACGTGCACCCCTTTTTTGTTTCTTTAG
3601 TGAATGCAAGATTTAATAAAAGTGAATAATGAGCTTCCCCTTTGGGAGTGGAGCCCAGTGCAGCTCACTGACAGGGTTGA
3681 CATCAGTATGATGTGTTGGACTGAAACTGTATGTCTGTAGGTAGGTGTGTGCCTTTTAGGGCAGACCACGGTGGCCACCC
3761 CATTTCTCCAAGGTGGTTTACCTAGCTTGTGTATATTAGACATTGCCACCCTCACCTCTGGCCAAAAATTCTTGATTTAA
3841 AAAGAAAAGTCTATTTTGTTAACGACAGGCTCTGTTGTATGTGTTACTATCCCAAGCCTGGATTATTTTATTTATTTAAA
3921 AGTATTTTAATTTCCATATTGGCTTTATTCTAATCCCATCCATCCCTGTGGAGCTGCAGAGCATCTTCATGTGAGTAGAC
4001 GGATGGACATAAATAGATTCATGCTCATTTAGGAAGCTGGGAGTTTCGTGAAGCTGAGGGTGAGTTCCTGTGATTCTTGT
4081 TCGCTTCAACAAAAAGTGGGAGACCAAGTTTTTATAGCAAAAGACCAAATTAGCTGTAGAGTCTTGAATGCAGAAAAAAA
4161 TTACCCTAGCTTTCTTAGCACTTAGGGTTTTGTGAGGATTCAGTGTTTAGCACAGTGCTTGGCACATAGTAAGCCCTAGT
4241 AAATGTTAAATATTGTTATTAGTGTTTCGTAAAACTTGAGAAATAGAGCTGAGCTCATTCCCTTCCTGTTGATTCAAAAA
4321 TAATACCTACATGAAAACATGATTCCAAGTTGATTGAATGTTGTAGGAATTACTGGTTTAGAGTAGCCCAGTTCTCGGCC
4401 TACCCTGCTGGTTGGGATCTTACTGTATTCTTGAATGCACTGGTTTGAAAATATGCCAGACTTCAGCCCCCAAGGAAACA
4481 AGGCTGCAAGAATTTATGAACTCCAGCTGGAAAAGGTAAAGGTGACCTTTGGCTAGCCACATACTGGACCTTACCCCACT
4561 GACGTCTTTCAGAACATTCCAAGGGTTTTCCTCAAGGAACATTTTTGAGCTAGAAATTAAAATGGGTTCTCTGGCAGACT
4641 GCACCCCTTGAGTCAAAGTTAACAGTATTCCTTTGAATGCAATAATAGAGGCTTTTCTGCGTTAAGGGAGAAGGAATGAC
4721 CAATTGAACTTACACATTCCCCAGGCAGGTCCCTTTGCCGGCCCCTACAGGCTGGGGTGGCCCCTCCTGTCCTCAGGGAT
4801 CAGACTCCCAGACTGGTTAGTTCTGCATGTTTCCATCAAATTAAAGGTTATTCCCTGGCCGCCTCCTGGAGAAAACCAAC
4881 CCCACCCTGCCAGCTGGGGGCAATGGGGCAGGGATTTTGGCCTCTCAGAACAGCTCCTAGAGGCTGCTCATGACTGAATG
4961 TTTTCCCAAATCACCTAAATATCGGTTTGCTTTTTGTTTTGGGGGAGAGGATTTAGCCTCTTACTTCCCTGATGGATTCA
5041 AAGTTTTATCTATCTCCTTATCTCCTGCCCTGTCTTGGCACAACTCTGGATAGATTGCAGGTGTGGAATTTGCTGGAGTT
5121 TGGTGACTTCGTCAAATTCCTTTGGATTCTGTTCCGCCAAATCAGCAGTCTCGTCCTGTGGATGCAGTGACTGGAATTTC
5201 CCATCTGCAAAGCATCTCTGTAGCCCAGATTTTGTGGAGCCTTAAGACACTCCCTCAATGCCACCCTGACCCCACGGCTG
5281 GAGAACCCTGTGCTTATGTGGTGGGCAGGGCCACTGTTGATGGAGGATGGCGGGGACGGGGTGGTGCTCAAAGGATCTGT
5361 GGTGCTGGAGGTCTACACGCCTCTCAGGACAGCGTGTCAGGAACCTCAGAGCAGCTTCACATCTGCCAAAGCTGAGAGGG
5441 AGCGAACTTGGGAAGCATTTTGCTCATTGTCCTACCCAAGTATTAATAGCATAATAGTTGATGCCAAAGGAGATGGTGAC
5521 GTCCCTTCCACTGTAGTTGCTGTCACAACCTTGACGTCTTTAAGCTAATGGCCGTTTGCATCTGTGTCTTCAAACAGATC
5601 CTGGTTACAGCCATTTTGTGTGATTCACTTCGGGGGTTAAGTAATGCAGGATTCTGCAAACAAGGTGTCGCCGTCCAAAT
5681 GTACTGTCCTGGCATAGAGAGCACTGCTTTGTTTTCCACTGTTGTAGAGAAAACTAGGGAGAACTTTATTTTTCAATAAA
5761 CTTTTCTTGTGTGAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' acgUCCGUCUUC------CC-----CACCACUCc 5'
             :||||||||      ||      ||||||| 
Target 5' gaaGGGCAGAAGTCCAAAGGAAACCTTGGTGAGt 3'
 1901 - 1934 154.00 -23.30
2 
miRNA  3' acgUCCGUCUUCC-CCACCACUcc 5'
             | ||  |||| | ||||||  
Target 5' ttgATGCCAAAGGAGATGGTGAcg 3'
 5498 - 5521 140.00 -15.40
3 
miRNA  3' acguCCG--UCUUCCCCACCACucc 5'
              |||  :|| |||||||||   
Target 5' ggatGGCGGGGACGGGGTGGTGctc 3'
 5325 - 5349 133.00 -26.32
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30156536 7 COSMIC
COSN17075309 540 COSMIC
COSN17075310 541 COSMIC
COSN15662469 616 COSMIC
COSN15662470 617 COSMIC
COSN6554307 869 COSMIC
COSN28274283 1071 COSMIC
COSN5781657 1092 COSMIC
COSN7339155 1365 COSMIC
COSN7339156 1505 COSMIC
COSN31959791 1522 COSMIC
COSN17007280 1547 COSMIC
COSN22870397 1700 COSMIC
COSN23451009 1785 COSMIC
COSN22827461 1826 COSMIC
COSN32065077 1974 COSMIC
COSN22452776 3035 COSMIC
COSN30223955 3291 COSMIC
COSN29481294 3309 COSMIC
COSN16693066 3408 COSMIC
COSN1789220 4120 COSMIC
COSN6210154 4414 COSMIC
COSN21246819 4825 COSMIC
COSN21937737 4935 COSMIC
COSN21401282 4957 COSMIC
COSN15282645 4980 COSMIC
COSN29788473 5164 COSMIC
COSN4796269 5338 COSMIC
COSN19149776 5493 COSMIC
COSN27968018 5670 COSMIC
COSN8758348 5689 COSMIC
COSN1789222 5741 COSMIC
rs78170588 1854 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs774103017 1 dbSNP
rs900618203 14 dbSNP
rs148616593 16 dbSNP
rs746204743 19 dbSNP
rs1454081815 22 dbSNP
rs1415321903 23 dbSNP
rs1286115322 25 dbSNP
rs772630622 26 dbSNP
rs1390441029 27 dbSNP
rs1384502223 28 dbSNP
rs1004443065 29 dbSNP
rs1338778495 31 dbSNP
rs556528641 32 dbSNP
rs1452026183 36 dbSNP
rs761276358 38 dbSNP
rs1319285115 42 dbSNP
rs1240170362 43 dbSNP
rs764219202 45 dbSNP
rs1326636567 46 dbSNP
rs776602017 49 dbSNP
rs202011729 50 dbSNP
rs578008805 57 dbSNP
rs933429939 58 dbSNP
rs973497935 60 dbSNP
rs1409815720 64 dbSNP
rs921663328 66 dbSNP
rs1424607327 68 dbSNP
rs1258706200 81 dbSNP
rs550920528 85 dbSNP
rs569517123 92 dbSNP
rs1052243640 99 dbSNP
rs1370181671 107 dbSNP
rs539784041 108 dbSNP
rs1440723576 110 dbSNP
rs1211097771 113 dbSNP
rs902528171 117 dbSNP
rs1237950671 118 dbSNP
rs999512920 122 dbSNP
rs1237965970 140 dbSNP
rs945928389 141 dbSNP
rs757375599 145 dbSNP
rs558127132 148 dbSNP
rs781446455 149 dbSNP
rs1406437554 150 dbSNP
rs1012861275 156 dbSNP
rs188429154 157 dbSNP
rs971263283 160 dbSNP
rs534190774 175 dbSNP
rs555860921 179 dbSNP
rs1399645599 187 dbSNP
rs894551502 190 dbSNP
rs1397247453 192 dbSNP
rs574215931 196 dbSNP
rs16830621 197 dbSNP
rs950417105 199 dbSNP
rs115651006 201 dbSNP
rs909174678 214 dbSNP
rs62170042 222 dbSNP
rs975032124 224 dbSNP
rs1191117903 226 dbSNP
rs1463931947 228 dbSNP
rs1017115329 230 dbSNP
rs1331617858 237 dbSNP
rs544929812 241 dbSNP
rs1229420644 243 dbSNP
rs180794807 251 dbSNP
rs1243289366 267 dbSNP
rs1255606839 274 dbSNP
rs1298054384 277 dbSNP
rs749721620 278 dbSNP
rs933126865 290 dbSNP
rs1317751267 294 dbSNP
rs1387386158 295 dbSNP
rs1051884287 297 dbSNP
rs185892174 302 dbSNP
rs1029112721 308 dbSNP
rs1279491648 310 dbSNP
rs953156129 315 dbSNP
rs1448219862 321 dbSNP
rs1372966214 324 dbSNP
rs1200155323 329 dbSNP
rs935358805 329 dbSNP
rs1179844393 330 dbSNP
rs987242804 335 dbSNP
rs111940474 344 dbSNP
rs1219882675 353 dbSNP
rs893775792 356 dbSNP
rs542793850 357 dbSNP
rs542238263 363 dbSNP
rs1275105200 364 dbSNP
rs1472770170 373 dbSNP
rs1197970211 376 dbSNP
rs1269953414 385 dbSNP
rs1315115258 388 dbSNP
rs1337405131 388 dbSNP
rs1375541628 391 dbSNP
rs1467321119 393 dbSNP
rs1172644624 395 dbSNP
rs1332970827 396 dbSNP
rs1489327857 397 dbSNP
rs1395073559 398 dbSNP
rs560628216 399 dbSNP
rs1310270184 400 dbSNP
rs977271982 401 dbSNP
rs1045520399 402 dbSNP
rs911339960 402 dbSNP
rs561432356 405 dbSNP
rs944008882 406 dbSNP
rs1041070930 410 dbSNP
rs531339916 417 dbSNP
rs370104529 418 dbSNP
rs1004107908 419 dbSNP
rs1035429985 420 dbSNP
rs1256819316 425 dbSNP
rs1201036917 426 dbSNP
rs1341498708 426 dbSNP
rs1281475210 428 dbSNP
rs1222932379 430 dbSNP
rs1351146146 439 dbSNP
rs1045762092 443 dbSNP
rs950470922 444 dbSNP
rs1440269418 458 dbSNP
rs1004539959 470 dbSNP
rs1015890985 471 dbSNP
rs887210057 477 dbSNP
rs1276667992 485 dbSNP
rs1335194270 489 dbSNP
rs1483365050 492 dbSNP
rs1209017420 516 dbSNP
rs681148 517 dbSNP
rs1400628085 519 dbSNP
rs1173675874 520 dbSNP
rs549947626 524 dbSNP
rs1468872153 525 dbSNP
rs1412036629 526 dbSNP
rs1038953989 529 dbSNP
rs753527657 530 dbSNP
rs562985214 536 dbSNP
rs765192213 537 dbSNP
rs1444088885 542 dbSNP
rs75506899 549 dbSNP
rs987707985 551 dbSNP
rs1329988551 557 dbSNP
rs924055438 570 dbSNP
rs1018683291 575 dbSNP
rs555439930 580 dbSNP
rs567184103 581 dbSNP
rs1053829318 582 dbSNP
rs1381001113 586 dbSNP
rs1336705648 591 dbSNP
rs1436448518 596 dbSNP
rs915261656 598 dbSNP
rs1160657233 606 dbSNP
rs1398611140 609 dbSNP
rs1302188457 612 dbSNP
rs1406732300 615 dbSNP
rs1364801374 618 dbSNP
rs1226241195 632 dbSNP
rs534152346 633 dbSNP
rs1241021506 636 dbSNP
rs1182979623 640 dbSNP
rs1465237555 649 dbSNP
rs1249996037 650 dbSNP
rs1213669218 651 dbSNP
rs1446667674 652 dbSNP
rs1230218492 659 dbSNP
rs772817014 660 dbSNP
rs1045350647 674 dbSNP
rs760522517 677 dbSNP
rs1243902500 688 dbSNP
rs991841422 689 dbSNP
rs915841079 691 dbSNP
rs1003756769 696 dbSNP
rs1263616899 700 dbSNP
rs1344066969 703 dbSNP
rs950029054 708 dbSNP
rs1426156938 718 dbSNP
rs1423083358 725 dbSNP
rs1489311334 730 dbSNP
rs1047213048 731 dbSNP
rs78235873 735 dbSNP
rs1450028791 736 dbSNP
rs1391898180 737 dbSNP
rs981409668 746 dbSNP
rs908600618 747 dbSNP
rs1004592292 748 dbSNP
rs1489902162 755 dbSNP
rs1463319048 764 dbSNP
rs1206257075 768 dbSNP
rs1344980060 775 dbSNP
rs1038535461 779 dbSNP
rs898684897 780 dbSNP
rs1360743564 787 dbSNP
rs1274851164 789 dbSNP
rs766393943 790 dbSNP
rs932906473 794 dbSNP
rs879820046 813 dbSNP
rs891402618 818 dbSNP
rs1302342798 825 dbSNP
rs1430208747 840 dbSNP
rs1300905817 850 dbSNP
rs1015943979 852 dbSNP
rs1427845376 854 dbSNP
rs1201617731 860 dbSNP
rs1425965790 860 dbSNP
rs1018655699 863 dbSNP
rs1268402473 865 dbSNP
rs902931657 867 dbSNP
rs1484272882 877 dbSNP
rs1249968202 882 dbSNP
rs59112286 884 dbSNP
rs1367261295 885 dbSNP
rs1032831937 886 dbSNP
rs1278738054 890 dbSNP
rs996225877 899 dbSNP
rs1459752903 902 dbSNP
rs1327046071 905 dbSNP
rs538003622 907 dbSNP
rs957400866 910 dbSNP
rs1410042651 911 dbSNP
rs573821179 911 dbSNP
rs556623428 913 dbSNP
rs759333832 914 dbSNP
rs971297053 917 dbSNP
rs577724734 918 dbSNP
rs981401774 920 dbSNP
rs878901921 923 dbSNP
rs1178721601 927 dbSNP
rs923770590 930 dbSNP
rs1310457957 936 dbSNP
rs956500479 940 dbSNP
rs1245238746 961 dbSNP
rs765159593 963 dbSNP
rs1248872512 964 dbSNP
rs1267326105 964 dbSNP
rs961425769 967 dbSNP
rs1239763766 969 dbSNP
rs915316835 970 dbSNP
rs948103888 986 dbSNP
rs538843299 990 dbSNP
rs553621967 991 dbSNP
rs1318289347 992 dbSNP
rs1482618244 995 dbSNP
rs1280849409 996 dbSNP
rs1338679600 1000 dbSNP
rs572037204 1003 dbSNP
rs1405442835 1016 dbSNP
rs1049929312 1030 dbSNP
rs939606849 1054 dbSNP
rs1362236004 1064 dbSNP
rs1254655658 1068 dbSNP
rs1424806555 1068 dbSNP
rs542199997 1081 dbSNP
rs887295796 1082 dbSNP
rs1166089120 1084 dbSNP
rs941503899 1087 dbSNP
rs1411616775 1091 dbSNP
rs1455979869 1101 dbSNP
rs1205154483 1104 dbSNP
rs1486663043 1120 dbSNP
rs1258633305 1121 dbSNP
rs1040043989 1123 dbSNP
rs1322170321 1124 dbSNP
rs1316804856 1133 dbSNP
rs1243698925 1140 dbSNP
rs1381882682 1142 dbSNP
rs1161597788 1145 dbSNP
rs1346062155 1146 dbSNP
rs751786372 1149 dbSNP
rs1301237640 1155 dbSNP
rs1037436232 1165 dbSNP
rs369057918 1166 dbSNP
rs1381236591 1168 dbSNP
rs1387478596 1168 dbSNP
rs1161996158 1172 dbSNP
rs1396472130 1179 dbSNP
rs1391286558 1180 dbSNP
rs902879403 1183 dbSNP
rs898907091 1189 dbSNP
rs148940502 1204 dbSNP
rs1348348265 1208 dbSNP
rs1490393696 1209 dbSNP
rs61244555 1213 dbSNP
rs1219924071 1220 dbSNP
rs1358421838 1229 dbSNP
rs1298300145 1231 dbSNP
rs890087005 1243 dbSNP
rs1013128377 1244 dbSNP
rs1022789453 1245 dbSNP
rs758425342 1248 dbSNP
rs1008835200 1251 dbSNP
rs1367631875 1257 dbSNP
rs1424475058 1267 dbSNP
rs971287182 1267 dbSNP
rs1371536908 1268 dbSNP
rs1002771515 1269 dbSNP
rs143703550 1272 dbSNP
rs956552583 1273 dbSNP
rs77999253 1274 dbSNP
rs564999324 1276 dbSNP
rs533328419 1288 dbSNP
rs370793041 1290 dbSNP
rs1490141063 1293 dbSNP
rs779646959 1294 dbSNP
rs1022418971 1295 dbSNP
rs1273441267 1304 dbSNP
rs1197487367 1308 dbSNP
rs1251771026 1313 dbSNP
rs1250852368 1317 dbSNP
rs969873052 1319 dbSNP
rs372462992 1323 dbSNP
rs927957425 1328 dbSNP
rs1281673963 1331 dbSNP
rs1404558911 1338 dbSNP
rs1351563018 1341 dbSNP
rs1331223818 1352 dbSNP
rs35867269 1354 dbSNP
rs912758373 1355 dbSNP
rs939332043 1356 dbSNP
rs1173636758 1357 dbSNP
rs544061317 1362 dbSNP
rs1469912123 1370 dbSNP
rs983009227 1380 dbSNP
rs908787656 1395 dbSNP
rs1173894109 1400 dbSNP
rs77592833 1404 dbSNP
rs111582118 1407 dbSNP
rs532691677 1408 dbSNP
rs1249782234 1412 dbSNP
rs562832186 1415 dbSNP
rs1325828665 1417 dbSNP
rs1012709085 1421 dbSNP
rs1223143015 1423 dbSNP
rs113074338 1433 dbSNP
rs571735868 1436 dbSNP
rs1307282909 1439 dbSNP
rs1335520767 1440 dbSNP
rs1338025223 1441 dbSNP
rs1455047044 1443 dbSNP
rs890128533 1448 dbSNP
rs1002674897 1454 dbSNP
rs1008552505 1457 dbSNP
rs1279994400 1470 dbSNP
rs538434044 1471 dbSNP
rs553584999 1473 dbSNP
rs897073685 1475 dbSNP
rs995880354 1483 dbSNP
rs1027024926 1486 dbSNP
rs571998745 1493 dbSNP
rs536191690 1505 dbSNP
rs1030944452 1506 dbSNP
rs892387050 1511 dbSNP
rs1447621149 1512 dbSNP
rs61501319 1522 dbSNP
rs575905516 1523 dbSNP
rs1203841531 1531 dbSNP
rs969210858 1536 dbSNP
rs543418991 1544 dbSNP
rs1482398160 1546 dbSNP
rs34944508 1547 dbSNP
rs559967584 1548 dbSNP
rs1319948192 1550 dbSNP
rs960725054 1552 dbSNP
rs982742545 1557 dbSNP
rs1267376428 1559 dbSNP
rs1163923699 1562 dbSNP
rs1477905691 1567 dbSNP
rs1189649642 1569 dbSNP
rs1427550260 1576 dbSNP
rs1182886377 1577 dbSNP
rs1475814526 1591 dbSNP
rs1243914798 1592 dbSNP
rs908832058 1593 dbSNP
rs1454745235 1608 dbSNP
rs936971583 1619 dbSNP
rs1292987049 1629 dbSNP
rs1225134013 1633 dbSNP
rs1357704637 1634 dbSNP
rs962940098 1635 dbSNP
rs990221471 1642 dbSNP
rs780552182 1644 dbSNP
rs576896545 1649 dbSNP
rs1271366742 1651 dbSNP
rs651970 1660 dbSNP
rs932804808 1676 dbSNP
rs1303344257 1677 dbSNP
rs1426366227 1677 dbSNP
rs1431617390 1679 dbSNP
rs1363467609 1682 dbSNP
rs1164076655 1684 dbSNP
rs755285259 1685 dbSNP
rs948463393 1690 dbSNP
rs1184806306 1694 dbSNP
rs911626956 1697 dbSNP
rs906980363 1710 dbSNP
rs944396089 1712 dbSNP
rs548830916 1721 dbSNP
rs1052094628 1722 dbSNP
rs1434072835 1728 dbSNP
rs1309723704 1729 dbSNP
rs1274534936 1730 dbSNP
rs1036833987 1731 dbSNP
rs1283589074 1737 dbSNP
rs1406385712 1738 dbSNP
rs1343414257 1745 dbSNP
rs1292671077 1746 dbSNP
rs567352814 1748 dbSNP
rs1010833970 1751 dbSNP
rs1371328455 1753 dbSNP
rs139106895 1754 dbSNP
rs3833552 1754 dbSNP
rs561931716 1754 dbSNP
rs565392910 1754 dbSNP
rs1027385849 1755 dbSNP
rs1294841358 1758 dbSNP
rs1178094872 1759 dbSNP
rs1481803289 1760 dbSNP
rs1231719119 1764 dbSNP
rs1204422974 1765 dbSNP
rs1043626550 1766 dbSNP
rs905038534 1767 dbSNP
rs1263143253 1768 dbSNP
rs560717236 1772 dbSNP
rs1343695895 1775 dbSNP
rs1002031606 1776 dbSNP
rs527893919 1777 dbSNP
rs960768895 1786 dbSNP
rs1274356563 1790 dbSNP
rs1320912178 1790 dbSNP
rs543304284 1792 dbSNP
rs1300368516 1795 dbSNP
rs626540 1796 dbSNP
rs1015550708 1804 dbSNP
rs1375228588 1809 dbSNP
rs1296441674 1814 dbSNP
rs531579496 1816 dbSNP
rs1248642965 1818 dbSNP
rs376931148 1818 dbSNP
rs1406932710 1820 dbSNP
rs1338719189 1827 dbSNP
rs974740640 1829 dbSNP
rs1187996370 1836 dbSNP
rs1468457258 1840 dbSNP
rs1388343906 1847 dbSNP
rs78170588 1854 dbSNP
rs1031207313 1855 dbSNP
rs571633842 1857 dbSNP
rs16830623 1858 dbSNP
rs1462111100 1865 dbSNP
rs916831244 1868 dbSNP
rs7581443 1876 dbSNP
rs948393143 1878 dbSNP
rs547185753 1882 dbSNP
rs911680113 1893 dbSNP
rs1394744874 1894 dbSNP
rs979743151 1901 dbSNP
rs1216051258 1906 dbSNP
rs1318575093 1907 dbSNP
rs1433825228 1913 dbSNP
rs1318131117 1926 dbSNP
rs1366687499 1928 dbSNP
rs1383380466 1929 dbSNP
rs1430847719 1929 dbSNP
rs944448650 1932 dbSNP
rs1289736628 1933 dbSNP
rs1343814802 1933 dbSNP
rs1401563414 1933 dbSNP
rs1455478624 1933 dbSNP
rs1271261402 1935 dbSNP
rs112441868 1937 dbSNP
rs1162228009 1937 dbSNP
rs1193244381 1937 dbSNP
rs1293929661 1937 dbSNP
rs1297786806 1937 dbSNP
rs1367440808 1937 dbSNP
rs1376572075 1937 dbSNP
rs1384156735 1937 dbSNP
rs1425741502 1937 dbSNP
rs1480338877 1937 dbSNP
rs199630266 1937 dbSNP
rs201780815 1937 dbSNP
rs569682209 1937 dbSNP
rs58666142 1937 dbSNP
rs72144957 1937 dbSNP
rs761976084 1937 dbSNP
rs778700607 1937 dbSNP
rs796492929 1937 dbSNP
rs879023522 1937 dbSNP
rs879145858 1937 dbSNP
rs879190150 1937 dbSNP
rs1491341413 1938 dbSNP
rs1192414320 1939 dbSNP
rs1226963328 1939 dbSNP
rs1490454684 1939 dbSNP
rs776596167 1941 dbSNP
rs1335936068 1943 dbSNP
rs1355532867 1945 dbSNP
rs913588682 1947 dbSNP
rs1229746174 1949 dbSNP
rs1246456979 1951 dbSNP
rs1466272725 1953 dbSNP
rs565489983 1956 dbSNP
rs1194057514 1958 dbSNP
rs1236826467 1962 dbSNP
rs113300199 1963 dbSNP
rs1471802123 1966 dbSNP
rs199684345 1967 dbSNP
rs1386753172 1968 dbSNP
rs1170103944 1972 dbSNP
rs1397794499 1972 dbSNP
rs1420756162 1974 dbSNP
rs1164944333 1976 dbSNP
rs1480553826 1977 dbSNP
rs1418222429 1978 dbSNP
rs946375603 1978 dbSNP
rs1450782945 1979 dbSNP
rs1197425412 1980 dbSNP
rs1456504188 1980 dbSNP
rs866725385 1980 dbSNP
rs1257498645 1981 dbSNP
rs938470408 1981 dbSNP
rs1044064850 1982 dbSNP
rs1156436019 1982 dbSNP
rs1325896713 1982 dbSNP
rs1390440820 1983 dbSNP
rs1331468742 1984 dbSNP
rs905091410 1984 dbSNP
rs1390167771 1985 dbSNP
rs868689549 1986 dbSNP
rs1333006912 1989 dbSNP
rs1036806003 1990 dbSNP
rs1340386146 1992 dbSNP
rs1431017956 2000 dbSNP
rs569952933 2002 dbSNP
rs1477582778 2006 dbSNP
rs1446393721 2016 dbSNP
rs931151382 2020 dbSNP
rs1183986247 2030 dbSNP
rs1437732245 2034 dbSNP
rs1237697170 2039 dbSNP
rs1204349107 2040 dbSNP
rs1356458796 2052 dbSNP
rs75561369 2058 dbSNP
rs1266452161 2062 dbSNP
rs1351937272 2070 dbSNP
rs1281628504 2074 dbSNP
rs1353162894 2075 dbSNP
rs1205774647 2081 dbSNP
rs889704594 2083 dbSNP
rs896283941 2086 dbSNP
rs1006861078 2091 dbSNP
rs1360335251 2094 dbSNP
rs1331797411 2099 dbSNP
rs1413550611 2107 dbSNP
rs533052796 2111 dbSNP
rs545039843 2117 dbSNP
rs1385474956 2120 dbSNP
rs1160063397 2122 dbSNP
rs576865274 2125 dbSNP
rs775506517 2132 dbSNP
rs1379645098 2135 dbSNP
rs901254746 2139 dbSNP
rs1015601244 2141 dbSNP
rs898528808 2143 dbSNP
rs1235736722 2156 dbSNP
rs1187182813 2158 dbSNP
rs1472129017 2167 dbSNP
rs1179796461 2171 dbSNP
rs995499218 2175 dbSNP
rs999635716 2177 dbSNP
rs1470342664 2180 dbSNP
rs1029030765 2182 dbSNP
rs139314811 2184 dbSNP
rs553115944 2185 dbSNP
rs1380794014 2186 dbSNP
rs572643093 2188 dbSNP
rs543267347 2204 dbSNP
rs561400432 2205 dbSNP
rs1446896217 2207 dbSNP
rs186784556 2208 dbSNP
rs1299606474 2223 dbSNP
rs1315302565 2227 dbSNP
rs1023852535 2228 dbSNP
rs1359592922 2232 dbSNP
rs969622477 2236 dbSNP
rs192035868 2248 dbSNP
rs1162711858 2258 dbSNP
rs1409570512 2263 dbSNP
rs1244081916 2268 dbSNP
rs928344526 2271 dbSNP
rs1488171149 2274 dbSNP
rs1270046597 2281 dbSNP
rs1225439984 2287 dbSNP
rs1286905485 2288 dbSNP
rs1320422313 2297 dbSNP
rs1337912358 2297 dbSNP
rs1239946967 2298 dbSNP
rs1227273329 2300 dbSNP
rs61442419 2302 dbSNP
rs1339413605 2303 dbSNP
rs1279711031 2306 dbSNP
rs959767963 2307 dbSNP
rs1274512986 2309 dbSNP
rs1342899394 2310 dbSNP
rs987901683 2318 dbSNP
rs913641141 2324 dbSNP
rs931119578 2333 dbSNP
rs946399446 2334 dbSNP
rs1425784498 2335 dbSNP
rs911131974 2336 dbSNP
rs1477610431 2342 dbSNP
rs1430490122 2348 dbSNP
rs1482725547 2349 dbSNP
rs767839350 2351 dbSNP
rs926247635 2354 dbSNP
rs1246657622 2357 dbSNP
rs1252336695 2358 dbSNP
rs1437905154 2369 dbSNP
rs937944700 2371 dbSNP
rs565327689 2383 dbSNP
rs1216470024 2384 dbSNP
rs1316893254 2396 dbSNP
rs560151593 2398 dbSNP
rs1041047801 2399 dbSNP
rs1365155804 2401 dbSNP
rs56687571 2404 dbSNP
rs1173765710 2407 dbSNP
rs939841916 2408 dbSNP
rs1402623072 2416 dbSNP
rs999540738 2418 dbSNP
rs1037098544 2421 dbSNP
rs1407150695 2423 dbSNP
rs898575902 2434 dbSNP
rs1178442584 2435 dbSNP
rs554023317 2452 dbSNP
rs1431813204 2456 dbSNP
rs1306719819 2461 dbSNP
rs1178350574 2462 dbSNP
rs1399029763 2463 dbSNP
rs1471432395 2465 dbSNP
rs756152770 2466 dbSNP
rs1196246457 2467 dbSNP
rs565851004 2467 dbSNP
rs529810196 2468 dbSNP
rs569832033 2476 dbSNP
rs1391163097 2489 dbSNP
rs75618578 2491 dbSNP
rs1019850340 2492 dbSNP
rs956221340 2493 dbSNP
rs952603973 2494 dbSNP
rs1226000192 2495 dbSNP
rs983966936 2499 dbSNP
rs1464724566 2502 dbSNP
rs1253038919 2504 dbSNP
rs911080908 2510 dbSNP
rs558582067 2515 dbSNP
rs1040955077 2519 dbSNP
rs1379028422 2521 dbSNP
rs1020756571 2526 dbSNP
rs1209075246 2539 dbSNP
rs967830961 2541 dbSNP
rs922531624 2542 dbSNP
rs1256239732 2547 dbSNP
rs979551673 2553 dbSNP
rs1255234593 2557 dbSNP
rs935280424 2558 dbSNP
rs1355523294 2564 dbSNP
rs1052875581 2568 dbSNP
rs893885050 2575 dbSNP
rs1383702547 2577 dbSNP
rs570424420 2579 dbSNP
rs1314919710 2581 dbSNP
rs946831524 2590 dbSNP
rs112683448 2607 dbSNP
rs905340203 2616 dbSNP
rs1402259953 2619 dbSNP
rs1447162405 2634 dbSNP
rs1358954999 2649 dbSNP
rs1168887075 2654 dbSNP
rs937645440 2656 dbSNP
rs1368590670 2657 dbSNP
rs992062843 2662 dbSNP
rs1003683569 2663 dbSNP
rs1255072672 2689 dbSNP
rs1421501263 2689 dbSNP
rs1462787254 2697 dbSNP
rs553077301 2702 dbSNP
rs1215873164 2704 dbSNP
rs199562098 2704 dbSNP
rs1036815966 2705 dbSNP
rs898290718 2717 dbSNP
rs1326835603 2719 dbSNP
rs1267105582 2723 dbSNP
rs2439568 2725 dbSNP
rs1433017469 2736 dbSNP
rs636975 2737 dbSNP
rs561261375 2738 dbSNP
rs1338986202 2746 dbSNP
rs1297951619 2754 dbSNP
rs1406139648 2755 dbSNP
rs59716052 2761 dbSNP
rs1393553396 2762 dbSNP
rs1008218731 2764 dbSNP
rs1041344247 2765 dbSNP
rs766438239 2779 dbSNP
rs1243795900 2781 dbSNP
rs1367310595 2782 dbSNP
rs892051667 2788 dbSNP
rs1336676125 2792 dbSNP
rs963848779 2795 dbSNP
rs150490571 2804 dbSNP
rs1010444705 2814 dbSNP
rs1247053052 2819 dbSNP
rs1192624707 2823 dbSNP
rs1463140112 2826 dbSNP
rs976584509 2828 dbSNP
rs138380145 2829 dbSNP
rs1207923698 2831 dbSNP
rs1488237898 2832 dbSNP
rs1264471646 2839 dbSNP
rs1258780497 2844 dbSNP
rs1316262277 2846 dbSNP
rs1429686751 2850 dbSNP
rs969266268 2853 dbSNP
rs1416061760 2855 dbSNP
rs1463375163 2856 dbSNP
rs1299825330 2859 dbSNP
rs544045843 2861 dbSNP
rs1033831332 2870 dbSNP
rs1331407790 2872 dbSNP
rs959093814 2873 dbSNP
rs1397705231 2874 dbSNP
rs991782268 2875 dbSNP
rs915252578 2879 dbSNP
rs917865720 2880 dbSNP
rs946750589 2884 dbSNP
rs1196743963 2886 dbSNP
rs1388242600 2894 dbSNP
rs1432504664 2903 dbSNP
rs1238912908 2930 dbSNP
rs1200637447 2932 dbSNP
rs75572937 2935 dbSNP
rs751496978 2937 dbSNP
rs576789743 2941 dbSNP
rs919789821 2953 dbSNP
rs1201182647 2960 dbSNP
rs931112106 2968 dbSNP
rs939485580 2970 dbSNP
rs1049868732 2977 dbSNP
rs911280418 2985 dbSNP
rs1378256074 2986 dbSNP
rs1312043411 2995 dbSNP
rs944060942 2996 dbSNP
rs1395315527 3007 dbSNP
rs1310521301 3009 dbSNP
rs1041060435 3014 dbSNP
rs994178456 3015 dbSNP
rs1170562850 3017 dbSNP
rs1465326586 3025 dbSNP
rs183918770 3027 dbSNP
rs1380865698 3028 dbSNP
rs1180366576 3033 dbSNP
rs1025295034 3037 dbSNP
rs891760431 3039 dbSNP
rs1237633610 3063 dbSNP
rs1233722148 3064 dbSNP
rs888082257 3084 dbSNP
rs149255956 3086 dbSNP
rs187679810 3090 dbSNP
rs530165070 3095 dbSNP
rs1288791901 3096 dbSNP
rs1243670123 3097 dbSNP
rs1238610553 3112 dbSNP
rs1350948217 3114 dbSNP
rs1278423635 3117 dbSNP
rs904716541 3118 dbSNP
rs1002091272 3129 dbSNP
rs1341928716 3134 dbSNP
rs1482646922 3139 dbSNP
rs1413953670 3143 dbSNP
rs1033474248 3149 dbSNP
rs34731290 3157 dbSNP
rs1360853389 3159 dbSNP
rs959106359 3163 dbSNP
rs1417772638 3166 dbSNP
rs669740 3174 dbSNP
rs1024601288 3175 dbSNP
rs961005736 3195 dbSNP
rs113670398 3200 dbSNP
rs919825455 3201 dbSNP
rs1187026808 3229 dbSNP
rs1411508622 3230 dbSNP
rs952601693 3232 dbSNP
rs1265783314 3242 dbSNP
rs1215151895 3245 dbSNP
rs988494160 3253 dbSNP
rs985697022 3265 dbSNP
rs911346087 3266 dbSNP
rs1357779500 3280 dbSNP
rs980744132 3281 dbSNP
rs200505417 3282 dbSNP
rs1026929097 3285 dbSNP
rs1340957732 3291 dbSNP
rs944113225 3292 dbSNP
rs939476069 3294 dbSNP
rs1041125864 3295 dbSNP
rs913247102 3298 dbSNP
rs1310966328 3299 dbSNP
rs1407161810 3302 dbSNP
rs919447835 3302 dbSNP
rs1411716634 3305 dbSNP
rs946015112 3307 dbSNP
rs191466259 3308 dbSNP
rs1049754719 3309 dbSNP
rs2290481 3310 dbSNP
rs937558475 3312 dbSNP
rs1039425090 3317 dbSNP
rs899583712 3318 dbSNP
rs1056373209 3322 dbSNP
rs182170088 3323 dbSNP
rs1279650348 3327 dbSNP
rs1216589280 3328 dbSNP
rs997960123 3329 dbSNP
rs762778644 3331 dbSNP
rs1013308171 3344 dbSNP
rs1029491070 3361 dbSNP
rs1348411321 3380 dbSNP
rs956720514 3388 dbSNP
rs1325270486 3389 dbSNP
rs1225042114 3394 dbSNP
rs144474967 3395 dbSNP
rs1009404307 3397 dbSNP
rs1307303615 3400 dbSNP
rs187044012 3402 dbSNP
rs968025158 3415 dbSNP
rs1426305732 3424 dbSNP
rs905735226 3435 dbSNP
rs896855677 3437 dbSNP
rs1244512778 3442 dbSNP
rs994220545 3457 dbSNP
rs1457780370 3463 dbSNP
rs926650296 3464 dbSNP
rs1196365636 3465 dbSNP
rs773433981 3468 dbSNP
rs547818870 3469 dbSNP
rs1365444838 3471 dbSNP
rs1302527426 3476 dbSNP
rs985362678 3477 dbSNP
rs1379126828 3481 dbSNP
rs1329635955 3488 dbSNP
rs535583963 3499 dbSNP
rs1018541644 3501 dbSNP
rs766449094 3506 dbSNP
rs929426795 3509 dbSNP
rs976860338 3516 dbSNP
rs1413078796 3531 dbSNP
rs137947517 3537 dbSNP
rs1159718394 3539 dbSNP
rs946069156 3545 dbSNP
rs909447204 3548 dbSNP
rs753984941 3554 dbSNP
rs75805028 3557 dbSNP
rs755779398 3561 dbSNP
rs937591555 3565 dbSNP
rs1056028898 3576 dbSNP
rs1237658530 3577 dbSNP
rs537262374 3579 dbSNP
rs1171924477 3580 dbSNP
rs1396796427 3585 dbSNP
rs1279530936 3592 dbSNP
rs1435195509 3592 dbSNP
rs142524975 3603 dbSNP
rs1240784408 3607 dbSNP
rs1307343969 3609 dbSNP
rs1352506015 3619 dbSNP
rs1444143227 3631 dbSNP
rs1391079349 3632 dbSNP
rs896002348 3634 dbSNP
rs1366519524 3645 dbSNP
rs1375147236 3646 dbSNP
rs950207957 3647 dbSNP
rs1046154993 3649 dbSNP
rs1422040851 3651 dbSNP
rs1381672659 3661 dbSNP
rs896909297 3663 dbSNP
rs1417951944 3664 dbSNP
rs1414086529 3667 dbSNP
rs1183174040 3669 dbSNP
rs79594066 3678 dbSNP
rs1347995520 3682 dbSNP
rs1217307984 3687 dbSNP
rs191482755 3689 dbSNP
rs1283748154 3699 dbSNP
rs1238444731 3704 dbSNP
rs888081895 3709 dbSNP
rs746265232 3712 dbSNP
rs1207108522 3713 dbSNP
rs1226816047 3716 dbSNP
rs1355280795 3717 dbSNP
rs2290482 3718 dbSNP
rs866166002 3719 dbSNP
rs1018189698 3721 dbSNP
rs965228742 3726 dbSNP
rs1488311318 3732 dbSNP
rs1022165939 3740 dbSNP
rs758745768 3749 dbSNP
rs574498661 3751 dbSNP
rs542271616 3762 dbSNP
rs1166548204 3763 dbSNP
rs1474008104 3779 dbSNP
rs976576472 3792 dbSNP
rs1020414602 3798 dbSNP
rs1002105617 3801 dbSNP
rs1454787529 3806 dbSNP
rs967874088 3807 dbSNP
rs1033569838 3815 dbSNP
rs563648859 3816 dbSNP
rs925963539 3822 dbSNP
rs1488885148 3824 dbSNP
rs992123275 3832 dbSNP
rs937330998 3835 dbSNP
rs992181184 3836 dbSNP
rs950864414 3846 dbSNP
rs867038338 3854 dbSNP
rs1170968567 3864 dbSNP
rs879299589 3865 dbSNP
rs1220868142 3867 dbSNP
rs778025454 3870 dbSNP
rs950258141 3872 dbSNP
rs1295585640 3876 dbSNP
rs1387848280 3878 dbSNP
rs1036484013 3879 dbSNP
rs1294740737 3881 dbSNP
rs919394342 3883 dbSNP
rs867614826 3887 dbSNP
rs530706137 3891 dbSNP
rs974964461 3896 dbSNP
rs1466995008 3898 dbSNP
rs923518638 3902 dbSNP
rs1433773618 3903 dbSNP
rs1192451798 3905 dbSNP
rs1270090165 3911 dbSNP
rs185250306 3920 dbSNP
rs1269328638 3929 dbSNP
rs888137671 3936 dbSNP
rs1216675650 3938 dbSNP
rs892205644 3941 dbSNP
rs1258958940 3952 dbSNP
rs1200758277 3956 dbSNP
rs756902882 3966 dbSNP
rs2290483 3973 dbSNP
rs1333361030 3981 dbSNP
rs901081634 3984 dbSNP
rs1212012925 3985 dbSNP
rs998068012 3990 dbSNP
rs528436813 4001 dbSNP
rs546615477 4002 dbSNP
rs1448513641 4006 dbSNP
rs903666630 4008 dbSNP
rs1167141880 4010 dbSNP
rs1466318611 4013 dbSNP
rs1379313029 4016 dbSNP
rs1275308687 4019 dbSNP
rs1453934946 4021 dbSNP
rs1002010595 4022 dbSNP
rs1468949891 4024 dbSNP
rs1436258308 4025 dbSNP
rs1250031617 4033 dbSNP
rs967212347 4041 dbSNP
rs568012292 4047 dbSNP
rs1000703090 4048 dbSNP
rs80233518 4049 dbSNP
rs1240281257 4062 dbSNP
rs1476386836 4064 dbSNP
rs1309322635 4083 dbSNP
rs1443694941 4084 dbSNP
rs1013996839 4090 dbSNP
rs1187056533 4094 dbSNP
rs373611322 4109 dbSNP
rs1327700449 4115 dbSNP
rs1412719971 4116 dbSNP
rs1026354797 4118 dbSNP
rs1311058745 4135 dbSNP
rs745430145 4138 dbSNP
rs958983043 4139 dbSNP
rs1434006891 4141 dbSNP
rs991446758 4142 dbSNP
rs77355111 4144 dbSNP
rs190095207 4145 dbSNP
rs1468619314 4147 dbSNP
rs1016776406 4154 dbSNP
rs984924265 4154 dbSNP
rs1444559294 4155 dbSNP
rs1255830837 4159 dbSNP
rs1394810935 4164 dbSNP
rs1456240734 4167 dbSNP
rs1488922512 4173 dbSNP
rs1315677172 4177 dbSNP
rs971632154 4177 dbSNP
rs1224980795 4198 dbSNP
rs964852086 4202 dbSNP
rs1278663453 4210 dbSNP
rs1245053996 4215 dbSNP
rs972250885 4218 dbSNP
rs1327694652 4228 dbSNP
rs1357190984 4228 dbSNP
rs1413895092 4239 dbSNP
rs1361111718 4241 dbSNP
rs1299894199 4244 dbSNP
rs919439834 4269 dbSNP
rs780070228 4270 dbSNP
rs1048640870 4286 dbSNP
rs1473885001 4287 dbSNP
rs1355168060 4288 dbSNP
rs749269751 4292 dbSNP
rs145994965 4294 dbSNP
rs558758337 4296 dbSNP
rs909627875 4302 dbSNP
rs1478321089 4312 dbSNP
rs1265982194 4325 dbSNP
rs1214271045 4328 dbSNP
rs1444843118 4340 dbSNP
rs192867568 4349 dbSNP
rs768474979 4355 dbSNP
rs1336539408 4357 dbSNP
rs1291003603 4360 dbSNP
rs1490316518 4362 dbSNP
rs185809443 4364 dbSNP
rs1043459463 4370 dbSNP
rs1271923173 4373 dbSNP
rs534941978 4393 dbSNP
rs1282175766 4397 dbSNP
rs998118924 4398 dbSNP
rs1216363088 4403 dbSNP
rs553264166 4406 dbSNP
rs574743209 4407 dbSNP
rs903614459 4409 dbSNP
rs1466531779 4417 dbSNP
rs937812960 4424 dbSNP
rs1475357607 4426 dbSNP
rs541883054 4431 dbSNP
rs1041627228 4438 dbSNP
rs557405646 4440 dbSNP
rs1000016396 4443 dbSNP
rs1054919423 4446 dbSNP
rs1033550116 4448 dbSNP
rs896404640 4450 dbSNP
rs1318406132 4457 dbSNP
rs958809849 4460 dbSNP
rs1013528263 4461 dbSNP
rs1169317251 4462 dbSNP
rs139933732 4465 dbSNP
rs1275314438 4466 dbSNP
rs1443206783 4467 dbSNP
rs546013435 4468 dbSNP
rs886414583 4471 dbSNP
rs527272445 4472 dbSNP
rs373395398 4481 dbSNP
rs971349382 4494 dbSNP
rs972316181 4499 dbSNP
rs1400803144 4503 dbSNP
rs919497802 4504 dbSNP
rs964822229 4507 dbSNP
rs1168818839 4517 dbSNP
rs1409704180 4520 dbSNP
rs564321169 4525 dbSNP
rs1426496882 4527 dbSNP
rs952350229 4528 dbSNP
rs111429473 4537 dbSNP
rs1250579494 4542 dbSNP
rs1413316642 4548 dbSNP
rs368075793 4554 dbSNP
rs1356523239 4556 dbSNP
rs1202201572 4560 dbSNP
rs989048094 4564 dbSNP
rs528296923 4565 dbSNP
rs910676710 4583 dbSNP
rs1345884644 4584 dbSNP
rs942428900 4593 dbSNP
rs975134690 4594 dbSNP
rs979517291 4601 dbSNP
rs74398272 4606 dbSNP
rs1375830199 4607 dbSNP
rs1224441814 4612 dbSNP
rs142217514 4624 dbSNP
rs1041681349 4626 dbSNP
rs571506462 4628 dbSNP
rs879694967 4630 dbSNP
rs903098216 4633 dbSNP
rs1433375450 4645 dbSNP
rs538822968 4666 dbSNP
rs150808077 4667 dbSNP
rs1172509599 4668 dbSNP
rs1419099106 4671 dbSNP
rs1409715250 4679 dbSNP
rs1437046429 4681 dbSNP
rs1480220976 4690 dbSNP
rs1054305514 4692 dbSNP
rs573972510 4694 dbSNP
rs894263776 4701 dbSNP
rs1047619497 4702 dbSNP
rs1012974084 4724 dbSNP
rs1171555611 4725 dbSNP
rs1024316772 4727 dbSNP
rs1223415176 4728 dbSNP
rs1380407661 4733 dbSNP
rs1295466181 4737 dbSNP
rs1394997005 4744 dbSNP
rs1375394932 4747 dbSNP
rs1037742377 4748 dbSNP
rs900568117 4758 dbSNP
rs907234188 4760 dbSNP
rs528852678 4761 dbSNP
rs550330688 4768 dbSNP
rs34570178 4770 dbSNP
rs1418079137 4772 dbSNP
rs1189828104 4773 dbSNP
rs1391203304 4780 dbSNP
rs1027013871 4781 dbSNP
rs954876625 4781 dbSNP
rs568915719 4785 dbSNP
rs1010823495 4788 dbSNP
rs1020500475 4796 dbSNP
rs969410718 4797 dbSNP
rs1259012732 4799 dbSNP
rs1215385759 4801 dbSNP
rs73960911 4803 dbSNP
rs1275227120 4808 dbSNP
rs1345823287 4809 dbSNP
rs1355221098 4810 dbSNP
rs1279453274 4811 dbSNP
rs1236352813 4813 dbSNP
rs1280982974 4828 dbSNP
rs1338479598 4832 dbSNP
rs368235390 4860 dbSNP
rs139231308 4861 dbSNP
rs1017790284 4862 dbSNP
rs570672688 4864 dbSNP
rs917685643 4878 dbSNP
rs541189750 4880 dbSNP
rs1166570172 4886 dbSNP
rs374731921 4887 dbSNP
rs975188769 4888 dbSNP
rs941964327 4900 dbSNP
rs1037691403 4901 dbSNP
rs1259524669 4908 dbSNP
rs553225636 4909 dbSNP
rs1176029729 4922 dbSNP
rs763423166 4923 dbSNP
rs1255128472 4928 dbSNP
rs1212042102 4930 dbSNP
rs1396265719 4935 dbSNP
rs922328729 4940 dbSNP
rs900474747 4941 dbSNP
rs1306294628 4943 dbSNP
rs933684243 4945 dbSNP
rs1295424965 4950 dbSNP
rs1381169309 4955 dbSNP
rs1399094099 4955 dbSNP
rs1327566816 4958 dbSNP
rs1438229286 4966 dbSNP
rs1393505713 4970 dbSNP
rs996196859 4978 dbSNP
rs977106557 4983 dbSNP
rs1410675839 4984 dbSNP
rs1325512903 4985 dbSNP
rs1463284791 4986 dbSNP
rs1368813124 4991 dbSNP
rs568690757 5000 dbSNP
rs149984807 5001 dbSNP
rs1054759394 5005 dbSNP
rs1396944351 5008 dbSNP
rs890543906 5010 dbSNP
rs189466732 5011 dbSNP
rs1251456468 5019 dbSNP
rs575691081 5025 dbSNP
rs1325854243 5038 dbSNP
rs551480745 5040 dbSNP
rs1010396912 5047 dbSNP
rs1348032898 5052 dbSNP
rs1304948259 5053 dbSNP
rs181049761 5054 dbSNP
rs1407654035 5055 dbSNP
rs948536478 5057 dbSNP
rs1369815469 5059 dbSNP
rs968980383 5060 dbSNP
rs1045830357 5063 dbSNP
rs546272207 5067 dbSNP
rs907286456 5068 dbSNP
rs1000433778 5079 dbSNP
rs1297590100 5082 dbSNP
rs79775263 5093 dbSNP
rs573039656 5095 dbSNP
rs549138059 5096 dbSNP
rs1396769598 5116 dbSNP
rs1171876831 5119 dbSNP
rs1364609429 5122 dbSNP
rs1184247707 5126 dbSNP
rs1041938 5127 dbSNP
rs990450964 5131 dbSNP
rs34497810 5132 dbSNP
rs554970653 5156 dbSNP
rs1375099417 5157 dbSNP
rs1343585025 5159 dbSNP
rs1018259946 5164 dbSNP
rs983283282 5167 dbSNP
rs907728723 5172 dbSNP
rs1333806201 5173 dbSNP
rs964899726 5174 dbSNP
rs976246390 5186 dbSNP
rs1377216771 5193 dbSNP
rs575984284 5194 dbSNP
rs1434262216 5197 dbSNP
rs1385750363 5202 dbSNP
rs1463073804 5211 dbSNP
rs921847918 5213 dbSNP
rs1451850936 5221 dbSNP
rs780935369 5226 dbSNP
rs1189120091 5228 dbSNP
rs1476357194 5230 dbSNP
rs1051798790 5245 dbSNP
rs78024851 5250 dbSNP
rs924320998 5257 dbSNP
rs1041877727 5266 dbSNP
rs957234512 5274 dbSNP
rs1348128614 5276 dbSNP
rs990113855 5277 dbSNP
rs1233681840 5282 dbSNP
rs1380391666 5287 dbSNP
rs1297680535 5288 dbSNP
rs915824333 5289 dbSNP
rs904661795 5299 dbSNP
rs1232510852 5308 dbSNP
rs1320401200 5308 dbSNP
rs185159508 5311 dbSNP
rs1034525546 5314 dbSNP
rs894740793 5315 dbSNP
rs543178090 5322 dbSNP
rs369672886 5329 dbSNP
rs929424761 5332 dbSNP
rs532952756 5333 dbSNP
rs1444713972 5338 dbSNP
rs1014694166 5339 dbSNP
rs1478335115 5343 dbSNP
rs887811823 5349 dbSNP
rs548799211 5353 dbSNP
rs551029265 5365 dbSNP
rs1039328238 5376 dbSNP
rs1340015216 5377 dbSNP
rs563351460 5379 dbSNP
rs1165758925 5380 dbSNP
rs1363262052 5389 dbSNP
rs1364540193 5392 dbSNP
rs900749560 5394 dbSNP
rs528642813 5395 dbSNP
rs1030507864 5410 dbSNP
rs931925427 5411 dbSNP
rs1323337272 5417 dbSNP
rs546825245 5419 dbSNP
rs966846637 5423 dbSNP
rs987471391 5432 dbSNP
rs1422280256 5438 dbSNP
rs7841 5444 dbSNP
rs535820407 5445 dbSNP
rs1388993931 5447 dbSNP
rs557637966 5453 dbSNP
rs1042172270 5459 dbSNP
rs1220572050 5461 dbSNP
rs768541032 5466 dbSNP
rs1357134276 5470 dbSNP
rs1212722688 5472 dbSNP
rs1233477157 5473 dbSNP
rs1304294943 5477 dbSNP
rs1305877707 5478 dbSNP
rs1369069354 5479 dbSNP
rs1293094837 5481 dbSNP
rs936140110 5488 dbSNP
rs1055924783 5493 dbSNP
rs1327496258 5496 dbSNP
rs1429643981 5496 dbSNP
rs1376548540 5499 dbSNP
rs1240609513 5508 dbSNP
rs990213245 5515 dbSNP
rs1173738630 5521 dbSNP
rs1263012853 5522 dbSNP
rs147686678 5529 dbSNP
rs373584360 5532 dbSNP
rs969949481 5543 dbSNP
rs1210815814 5547 dbSNP
rs1234371077 5549 dbSNP
rs1470422455 5549 dbSNP
rs1202403309 5555 dbSNP
rs142454060 5556 dbSNP
rs1213120170 5557 dbSNP
rs906166193 5557 dbSNP
rs1182619766 5564 dbSNP
rs1345813860 5568 dbSNP
rs558254388 5574 dbSNP
rs928484024 5575 dbSNP
rs878907165 5580 dbSNP
rs1376040339 5583 dbSNP
rs1407597520 5583 dbSNP
rs1409541471 5585 dbSNP
rs762523584 5591 dbSNP
rs963157814 5598 dbSNP
rs994670327 5599 dbSNP
rs144758484 5609 dbSNP
rs1161464299 5611 dbSNP
rs1321474997 5621 dbSNP
rs1400896512 5621 dbSNP
rs1381012770 5624 dbSNP
rs1409642899 5625 dbSNP
rs1179764527 5632 dbSNP
rs747837165 5633 dbSNP
rs1433945167 5636 dbSNP
rs1171716682 5638 dbSNP
rs1189968809 5638 dbSNP
rs1376995725 5639 dbSNP
rs1203610443 5653 dbSNP
rs1318974696 5657 dbSNP
rs188693246 5665 dbSNP
rs942078209 5670 dbSNP
rs766313474 5671 dbSNP
rs1295713946 5672 dbSNP
rs377042698 5673 dbSNP
rs1376390089 5674 dbSNP
rs771902078 5679 dbSNP
rs1307014532 5681 dbSNP
rs1039061675 5689 dbSNP
rs967746291 5692 dbSNP
rs776789580 5696 dbSNP
rs1156503230 5704 dbSNP
rs1234152779 5708 dbSNP
rs926034778 5719 dbSNP
rs1350478318 5720 dbSNP
rs1211314480 5724 dbSNP
rs1167070598 5743 dbSNP
rs997788097 5744 dbSNP
rs1422022193 5745 dbSNP
rs1232519184 5746 dbSNP
rs1191413323 5761 dbSNP
rs1479816398 5764 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HeLa
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in Chi_ControlA_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control A HITS-CLIP data was present in Chi_ControlB_2A8_130_50. RNA binding protein: AGO. Condition:HeLa cell Control B ...

- Chi SW; Zang JB; Mele A; Darnell RB, 2009, Nature.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' acguccgucuucccCAC-CACUCc 5'
                        ||| ||||| 
Target 5' --------------GUGAGUGAGu 3'
 		1 - 10
Article - Chi SW; Zang JB; Mele A; Darnell RB
- Nature, 2009
MicroRNAs (miRNAs) have critical roles in the regulation of gene expression; however, as miRNA activity requires base pairing with only 6-8 nucleotides of messenger RNA, predicting target mRNAs is a major challenge. Recently, high-throughput sequencing of RNAs isolated by crosslinking immunoprecipitation (HITS-CLIP) has identified functional protein-RNA interaction sites. Here we use HITS-CLIP to covalently crosslink native argonaute (Ago, also called Eif2c) protein-RNA complexes in mouse brain. This produced two simultaneous data sets-Ago-miRNA and Ago-mRNA binding sites-that were combined with bioinformatic analysis to identify interaction sites between miRNA and target mRNA. We validated genome-wide interaction maps for miR-124, and generated additional maps for the 20 most abundant miRNAs present in P13 mouse brain. Ago HITS-CLIP provides a general platform for exploring the specificity and range of miRNA action in vivo, and identifies precise sequences for targeting clinically relevant miRNA-mRNA interactions.
LinkOut: [PMID: 19536157]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 4249.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714646. RNA binding protein: AGO2. Condition:mildMNase ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
Experimental Support 3 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Hela
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1048187. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_control HITS-CLIP data was present in GSM1048188. RNA binding protein: AGO2. Condition:Hela_AGO2_CLIP_ptb_knockdown ...

- Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al., 2013, Cell.

Article - Xue Y; Ouyang K; Huang J; Zhou Y; Ouyang H; et al.
- Cell, 2013
The induction of pluripotency or trans-differentiation of one cell type to another can be accomplished with cell-lineage-specific transcription factors. Here, we report that repression of a single RNA binding polypyrimidine-tract-binding (PTB) protein, which occurs during normal brain development via the action of miR-124, is sufficient to induce trans-differentiation of fibroblasts into functional neurons. Besides its traditional role in regulated splicing, we show that PTB has a previously undocumented function in the regulation of microRNA functions, suppressing or enhancing microRNA targeting by competitive binding on target mRNA or altering local RNA secondary structure. A key event during neuronal induction is the relief of PTB-mediated blockage of microRNA action on multiple components of the REST complex, thereby derepressing a large array of neuronal genes, including miR-124 and multiple neuronal-specific transcription factors, in nonneuronal cells. This converts a negative feedback loop to a positive one to elicit cellular reprogramming to the neuronal lineage.
LinkOut: [PMID: 23313552]
Experimental Support 4 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293S
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM1084040. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep1 HITS-CLIP data was present in GSM1084041. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep1 HITS-CLIP data was present in GSM1084042. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep2 HITS-CLIP data was present in GSM1084043. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep2 HITS-CLIP data was present in GSM1084044. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep3 HITS-CLIP data was present in GSM1084045. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep3 HITS-CLIP data was present in GSM1084046. RNA binding protein: AGO2. Condition:CLIP_noarsenite_rep4 HITS-CLIP data was present in GSM1084047. RNA binding protein: AGO2. Condition:CLIP_arsenite_rep4 HITS-CLIP data was present in GSM1084064. RNA binding protein: AGO2. Condition:CLIP_noemetine_AbnovaAb HITS-CLIP data was present in GSM1084065. RNA binding protein: AGO2. Condition:CLIP_emetine_AbnovaAb HITS-CLIP data was present in GSM1084068. RNA binding protein: AGO2. Condition:CLIP_noemetine_SigmaAb HITS-CLIP data was present in GSM1084069. RNA binding protein: AGO2. Condition:CLIP_emetine_SigmaAb HITS-CLIP data was present in GSM1084072. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084073. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_AbnovaAb HITS-CLIP data was present in GSM1084076. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084077. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep1_SigmaAb HITS-CLIP data was present in GSM1084078. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084079. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_AbnovaAb HITS-CLIP data was present in GSM1084081. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SantaCruzAb HITS-CLIP data was present in GSM1084082. RNA binding protein: AGO2. Condition:CLIP_nohippuristanol_rep2_SigmaAb HITS-CLIP data was present in GSM1084083. RNA binding protein: AGO2. Condition:CLIP_hippuristanol_rep2_SigmaAb ...

- Karginov FV; Hannon GJ, 2013, Genes & development.

Article - Karginov FV; Hannon GJ
- Genes & development, 2013
When adapting to environmental stress, cells attenuate and reprogram their translational output. In part, these altered translation profiles are established through changes in the interactions between RNA-binding proteins and mRNAs. The Argonaute 2 (Ago2)/microRNA (miRNA) machinery has been shown to participate in stress-induced translational up-regulation of a particular mRNA, CAT-1; however, a detailed, transcriptome-wide understanding of the involvement of Ago2 in the process has been lacking. Here, we profiled the overall changes in Ago2-mRNA interactions upon arsenite stress by cross-linking immunoprecipitation (CLIP) followed by high-throughput sequencing (CLIP-seq). Ago2 displayed a significant remodeling of its transcript occupancy, with the majority of 3' untranslated region (UTR) and coding sequence (CDS) sites exhibiting stronger interaction. Interestingly, target sites that were destined for release from Ago2 upon stress were depleted in miRNA complementarity signatures, suggesting an alternative mode of interaction. To compare the changes in Ago2-binding patterns across transcripts with changes in their translational states, we measured mRNA profiles on ribosome/polysome gradients by RNA sequencing (RNA-seq). Increased Ago2 occupancy correlated with stronger repression of translation for those mRNAs, as evidenced by a shift toward lighter gradient fractions upon stress, while release of Ago2 was associated with the limited number of transcripts that remained translated. Taken together, these data point to a role for Ago2 and the mammalian miRNAs in mediating the translational component of the stress response.
LinkOut: [PMID: 23824327]
Experimental Support 5 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions Cardiac Tissues
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... HITS-CLIP data was present in GSM2202476. RNA binding protein: AGO2. Condition:S1_LV_54yo_Male_AGO2_bound_RNA HITS-CLIP data was present in GSM2202478. RNA binding protein: AGO2. Condition:S3_LV_36yo_Male_AGO2_bound_RNA HITS-CLIP data was present in GSM2202480. RNA binding protein: AGO2. Condition:S5_LV_36yo_Male_AGO2_bound_RNA HITS-CLIP data was present in GSM2202477. RNA binding protein: AGO2. Condition:S2_LV_25yo_Male_AGO2_bound_RNA HITS-CLIP data was present in GSM2202479. RNA binding protein: AGO2. Condition:S4_LV_29yo_Male_AGO2_bound_RNA ...

- Spengler RM; Zhang X; Cheng C; McLendon JM; et al., 2016, Nucleic acids research.

Article - Spengler RM; Zhang X; Cheng C; McLendon JM; et al.
- Nucleic acids research, 2016
MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biological entities and attractive therapeutic targets, the translational impacts of miR research remain limited by a paucity of empirical miR targeting data, particularly in human primary tissues. Here, to improve our understanding of the diverse roles miRs play in cardiovascular function and disease, we applied high-throughput methods to globally profile miR:target interactions in human heart tissues. We deciphered Ago2:RNA interactions using crosslinking immunoprecipitation coupled with high-throughput sequencing (HITS-CLIP) to generate the first transcriptome-wide map of miR targeting events in human myocardium, detecting 4000 cardiac Ago2 binding sites across >2200 target transcripts. Our initial exploration of this interactome revealed an abundance of miR target sites in gene coding regions, including several sites pointing to new miR-29 functions in regulating cardiomyocyte calcium, growth and metabolism. Also, we uncovered several clinically-relevant interactions involving common genetic variants that alter miR targeting events in cardiomyopathy-associated genes. Overall, these data provide a critical resource for bolstering translational miR research in heart, and likely beyond.
LinkOut: [PMID: 27418678]
CLIP-seq Support 1 for dataset Chi_ControlA_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control A
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset Chi_ControlB_2A8_130_50
Method / RBP HITS-CLIP / AGO
Cell line / Condition HeLa / HeLa cell Control B
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 19536157 / Chi_HITSCLIP
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM1048187
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_control
Location of target site ENST00000409645.1 | 3UTR | AGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM1048188
Method / RBP HITS-CLIP / AGO2
Cell line / Condition Hela / Hela_AGO2_CLIP_ptb_knockdown
Location of target site ENST00000409645.1 | 3UTR | AAGGAAACCUUGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23313552 / GSE42701
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM1084040
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep1
Location of target site ENST00000409645.1 | 3UTR | UGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM1084041
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep1
Location of target site ENST00000409645.1 | 3UTR | UGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 8 for dataset GSM1084042
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep2
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 9 for dataset GSM1084043
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep2
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 10 for dataset GSM1084044
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep3
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 11 for dataset GSM1084045
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep3
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 12 for dataset GSM1084046
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noarsenite_rep4
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 13 for dataset GSM1084047
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_arsenite_rep4
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 14 for dataset GSM1084064
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | AGAAGUCCAAAGGAAACCUUGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 15 for dataset GSM1084065
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | UGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 16 for dataset GSM1084068
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_noemetine_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | CUUGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 17 for dataset GSM1084069
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_emetine_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 18 for dataset GSM1084072
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 19 for dataset GSM1084073
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 20 for dataset GSM1084076
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep1_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGAGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 21 for dataset GSM1084077
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep1_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 22 for dataset GSM1084078
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | AAAGGAAACCUUGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 23 for dataset GSM1084079
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_AbnovaAb
Location of target site ENST00000409645.1 | 3UTR | AAAGGAAACCUUGGUGAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 24 for dataset GSM1084081
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SantaCruzAb
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 25 for dataset GSM1084082
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_nohippuristanol_rep2_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | GAGUGAGUGUGUGUGUGUGUGUGUGUGUGUGUGUGUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 26 for dataset GSM1084083
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293S / CLIP_hippuristanol_rep2_SigmaAb
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 23824327 / GSE44404
CLIP-seq Viewer Link
CLIP-seq Support 27 for dataset GSM714646
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / mildMNase, repA
Location of target site ENST00000409645.1 | 3UTR | GUGAGUGUGUGUGUGUGUGUGUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
69 hsa-miR-6511b-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT059269 CELF1 CUGBP Elav-like family member 1 2 2
MIRT061287 IPO7 importin 7 2 2
MIRT115533 MAZ MYC associated zinc finger protein 2 2
MIRT345986 BIRC5 baculoviral IAP repeat containing 5 2 8
MIRT379536 HNRNPK heterogeneous nuclear ribonucleoprotein K 2 2
MIRT442491 RBBP5 RB binding protein 5, histone lysine methyltransferase complex subunit 2 8
MIRT443701 HUNK hormonally up-regulated Neu-associated kinase 2 4
MIRT459167 HSPA6 heat shock protein family A (Hsp70) member 6 2 21
MIRT497179 ZBTB40 zinc finger and BTB domain containing 40 2 2
MIRT497846 GATA6 GATA binding protein 6 2 4
MIRT519625 ZNF781 zinc finger protein 781 2 2
MIRT519838 ZFP69B ZFP69 zinc finger protein B 2 4
MIRT528560 DNAAF3 dynein axonemal assembly factor 3 2 2
MIRT530718 ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2 2
MIRT530810 GPR182 G protein-coupled receptor 182 2 2
MIRT533265 VAV3 vav guanine nucleotide exchange factor 3 2 4
MIRT533726 TMEM246 transmembrane protein 246 2 2
MIRT535547 P2RY2 purinergic receptor P2Y2 2 2
MIRT536019 MCUR1 mitochondrial calcium uniporter regulator 1 2 2
MIRT539494 ACTN4 actinin alpha 4 2 2
MIRT541793 MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2 8
MIRT554509 RUNX1T1 RUNX1 translocation partner 1 2 2
MIRT558784 CEP55 centrosomal protein 55 2 2
MIRT560013 ZNF525 zinc finger protein 525 2 2
MIRT560078 ZNF195 zinc finger protein 195 2 2
MIRT570135 IL1RL2 interleukin 1 receptor like 2 2 2
MIRT570890 ZNF780A zinc finger protein 780A 2 2
MIRT607972 SNX22 sorting nexin 22 2 2
MIRT608104 CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 2 2
MIRT610471 ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 2 4
MIRT611134 GGT7 gamma-glutamyltransferase 7 2 2
MIRT611448 NRIP3 nuclear receptor interacting protein 3 2 2
MIRT613019 GABPB1 GA binding protein transcription factor beta subunit 1 2 4
MIRT615753 C6 complement C6 2 2
MIRT620464 CERS6 ceramide synthase 6 2 2
MIRT632248 VPS41 VPS41, HOPS complex subunit 2 2
MIRT636099 ZDHHC22 zinc finger DHHC-type containing 22 2 2
MIRT637452 ZNF324B zinc finger protein 324B 2 2
MIRT638927 CALCOCO2 calcium binding and coiled-coil domain 2 2 2
MIRT646768 WDR3 WD repeat domain 3 2 2
MIRT652610 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT652868 TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 2 2
MIRT653655 SLC27A4 solute carrier family 27 member 4 2 2
MIRT657089 JMY junction mediating and regulatory protein, p53 cofactor 2 2
MIRT657884 GFPT1 glutamine--fructose-6-phosphate transaminase 1 2 2
MIRT662919 MED18 mediator complex subunit 18 2 2
MIRT685622 C12orf49 chromosome 12 open reading frame 49 2 2
MIRT687427 NRIP1 nuclear receptor interacting protein 1 2 2
MIRT692304 CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2 2
MIRT695127 PRY2 PTPN13-like, Y-linked 2 2 2
MIRT695144 PRY PTPN13-like, Y-linked 2 2
MIRT696286 IER3IP1 immediate early response 3 interacting protein 1 2 2
MIRT699350 SLC35E1 solute carrier family 35 member E1 2 2
MIRT709901 AGO1 argonaute 1, RISC catalytic component 2 2
MIRT710877 SLC25A42 solute carrier family 25 member 42 2 2
MIRT711365 MED7 mediator complex subunit 7 2 2
MIRT711444 FRMPD3 FERM and PDZ domain containing 3 2 2
MIRT713221 RCAN2 regulator of calcineurin 2 2 2
MIRT713281 LAIR1 leukocyte associated immunoglobulin like receptor 1 2 2
MIRT714195 TRAF7 TNF receptor associated factor 7 2 2
MIRT715152 IL12B interleukin 12B 2 2
MIRT719197 CASP10 caspase 10 2 2
MIRT719469 SRF serum response factor 2 2
MIRT720197 MPP6 membrane palmitoylated protein 6 2 2
MIRT720449 SLC16A5 solute carrier family 16 member 5 2 2
MIRT720461 RAB31 RAB31, member RAS oncogene family 2 2
MIRT721646 ZNF207 zinc finger protein 207 2 2
MIRT722001 CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand 2 2
MIRT725521 FAM229B family with sequence similarity 229 member B 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-6511b-3p Imatinib 5291 NSC743414 approved sensitive High Chronic Myelogenous Leukemia tissue
hsa-miR-6511b-3p Gefitinib 123631 NSC715055 approved sensitive cell line (HCC827)
hsa-miR-6511b-3p Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-6511b-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-6511b-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-miR-6511b-3p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)

Error report submission