miRTarBase - #MIRT543976


—
pre-miRNA Information
pre-miRNA hsa-mir-1284   
Genomic Coordinates chr3: 71541970 - 71542089
Synonyms MIRN1284, hsa-mir-1284, MIR1284
Description Homo sapiens miR-1284 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-1284
Sequence 30| UCUAUACAGACCCUGGCUUUUC |51
Evidence Experimental
Experiments Illumina
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN30511077 21 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1214878057 1 dbSNP
rs1247879523 2 dbSNP
rs1463875891 2 dbSNP
rs917753908 4 dbSNP
rs370463488 6 dbSNP
rs1423493129 7 dbSNP
rs1471537963 7 dbSNP
rs764647172 11 dbSNP
rs763621942 12 dbSNP
rs775929072 14 dbSNP
rs1461964877 17 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PRR23A   
Synonyms -
Description proline rich 23A
Transcript NM_001134659   
Expression
Putative miRNA Targets on PRR23A
3'UTR of PRR23A
(miRNA target sites are highlighted)		 
>PRR23A|NM_001134659|3'UTR
   1 ACTGCTTCCCACAATCCCTTGCCACCGGCTGCGGGTTCTTGTGGATCCTCCAAGACTCACTGTGAGGACTTGCCACAGCC
  81 CGGAAATGCAGCATCTTCATTCATCGACAGCGGGCAGTTGGATTACTGTTGTTTGGGTGGGTTGGTTGGTTGGCTGGCTG
 161 GCTGGTTGGTTTTTTGGCAGAATTCCTTGGTAAGTGGCAGGCAAGGACATGAAAAAAGAAAAGCAGATTCTGGTAAGCAC
 241 CTTTACCAAGAAGAGTAGACCACACATAACCAGTCATGGATTTTCAGATCCCTTGCCTTTGCTGCAGGAGCTGTTACTTC
 321 TGCCTTTGTCACCTTCAGCCAACTGTATCCTCAGTTTCACCCCTACTCTTGCTTAAAGCTCCCTTCAGTTTTCTTTAAAA
 401 TTCCCCCCTTTTTTTTTATCACTTCCATACACCTATCCGTTCTCTCCAATCCAGATCATTGTCTTTCCTTCTTTTTGCAG
 481 TTAGGAATTTACCTATACGATTTCTCCCAACATCCTCTGAGGTGCTTCTGACCACTGATTTTATTTTCCACTTGCTCTCC
 561 TTAACTCCTTTTCCTGGACCTGGACAATCAAGATAAATGCATATTAGATTAGATAGTAAACAAACAACATTCAAATGTAA
 641 TGAATGCACTGGACCTTTTGGAAGTGTTTCTGCAAATAAGAATTTAAGGGCCGGGCGCGATGGCTCACGCCTGTAATCCC
 721 AGCACTTTGGGAGGCCGAGGCGTGTGGATCACCTGCAGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGCGAAACTCCG
 801 TCTCTACTAAAAATACGAAAATTAGCCGGGCATGGTGGCGTGTGCCTGTAATCCCAGCTACTAGCAGGGATGAGGCAGGA
 881 GGAGTGCTTGAACCTGAGAGGCAGAGGTTGCAATGAGCCGAGATCGTGCCATTGCACTCCAGCCTGGGCAACAGAGTGAG
 961 ACTCCATCTCAAAAAAAAAAAAAAGAAAACGAAAAAACAATTTAAAAATTAGTGAAAGCAATATTTAATGAGGGAAAGTA
1041 GGAAGTTGTGACACTTTCATTCCAGCAGCATCTTGTACAATGACATATTCTATGTACTTTAACCAATGGGTATTCCTGAA
1121 TTTCAGGGCAGTGTGGGCTTCATCTTGATTTCCTCTCAGGGGTACTCACTCACCTTCACCGCATGGACATTTGGTCTAAT
1201 TTATTTTTGAGAGTTTTTTTCATGCTCTTGAGTCCATCACCCTGAATTGGCAGTCGTTATTTCTTAGTATTATTTCCTTA
1281 ATGTCTTTTTAACTATAAAGGAAAGGAAATATTACAGATAATGTTGTCATATCCTTTGATCCCCACTCTTCTCCCCCATT
1361 CCCAGGGGATTCACATCATGACACAAAGTTGATGGATATCATTCTAGTCAATATATGAAAGCTACATATACATATATATA
1441 TGTATAGATATAAATAAGCAATGTTTATGTTGTTTTCTGGACAATTAAATTTACATAACTACCTCA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuuucggucccAGACAUAUCu 5'
                      | ||||||| 
Target 5' tatacatatataTATGTATAGa 3'
 1427 - 1448 142.00 -7.70
2 
miRNA  3' cuuuUCGGUCCCAGACAUAucu 5'
              |||||    ||||||   
Target 5' cttcAGCCA---ACTGTATcct 3'
 333 - 351 115.00 -9.12
3 
miRNA  3' cuUUUCGGUCCCAGACAUAUCu 5'
            ||  :||||| | ||:|:| 
Target 5' tgAATTTCAGGG-CAGTGTGGg 3'
 1117 - 1137 103.00 -15.60
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1553877 484 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1287422250 2 dbSNP
rs180686917 4 dbSNP
rs765480383 6 dbSNP
rs529747107 7 dbSNP
rs1443914680 8 dbSNP
rs1337606431 9 dbSNP
rs1369460425 12 dbSNP
rs1235801656 17 dbSNP
rs776663477 26 dbSNP
rs1303509779 27 dbSNP
rs1179977284 28 dbSNP
rs764383708 33 dbSNP
rs1249410243 35 dbSNP
rs892056715 38 dbSNP
rs1056686996 39 dbSNP
rs540539328 42 dbSNP
rs1049732983 45 dbSNP
rs1264027648 48 dbSNP
rs1209140055 51 dbSNP
rs1251006190 52 dbSNP
rs905613185 60 dbSNP
rs1044155125 63 dbSNP
rs1469788847 66 dbSNP
rs372423981 73 dbSNP
rs759591785 74 dbSNP
rs931375404 78 dbSNP
rs941857148 80 dbSNP
rs1418706326 81 dbSNP
rs1157279651 82 dbSNP
rs561076491 88 dbSNP
rs1316566959 89 dbSNP
rs909018767 91 dbSNP
rs1325689531 92 dbSNP
rs1392835901 100 dbSNP
rs983319236 105 dbSNP
rs929173484 106 dbSNP
rs774322544 109 dbSNP
rs1328511886 111 dbSNP
rs1221688992 112 dbSNP
rs1308755581 115 dbSNP
rs976739927 115 dbSNP
rs1311039601 132 dbSNP
rs1243740038 135 dbSNP
rs1010187 137 dbSNP
rs1336784035 143 dbSNP
rs907783004 143 dbSNP
rs1253699200 148 dbSNP
rs1018352709 150 dbSNP
rs771050337 154 dbSNP
rs1175581477 156 dbSNP
rs985924348 157 dbSNP
rs1419901864 165 dbSNP
rs938588374 166 dbSNP
rs968843527 169 dbSNP
rs1395670139 176 dbSNP
rs1463474271 176 dbSNP
rs1022176283 185 dbSNP
rs1407191860 190 dbSNP
rs1353388401 197 dbSNP
rs979782759 200 dbSNP
rs968437601 201 dbSNP
rs914333620 202 dbSNP
rs771417279 203 dbSNP
rs1338758052 205 dbSNP
rs1010406856 209 dbSNP
rs76579185 217 dbSNP
rs1399686357 221 dbSNP
rs1167208570 222 dbSNP
rs1257293002 224 dbSNP
rs1462445749 226 dbSNP
rs1035937935 228 dbSNP
rs1185227327 233 dbSNP
rs1253163120 237 dbSNP
rs1481076782 250 dbSNP
rs558402191 253 dbSNP
rs1255814735 265 dbSNP
rs905561391 271 dbSNP
rs1476421076 275 dbSNP
rs1044087737 279 dbSNP
rs941748463 301 dbSNP
rs887544797 304 dbSNP
rs1408714846 315 dbSNP
rs1048016050 316 dbSNP
rs929187366 321 dbSNP
rs1243425179 322 dbSNP
rs1028264522 325 dbSNP
rs544916608 348 dbSNP
rs1456036779 349 dbSNP
rs1269384650 368 dbSNP
rs923168774 369 dbSNP
rs898579529 370 dbSNP
rs1297816814 374 dbSNP
rs976018462 375 dbSNP
rs1308199735 403 dbSNP
rs1342169231 404 dbSNP
rs575961615 405 dbSNP
rs911195947 408 dbSNP
rs1211955229 409 dbSNP
rs1491565604 409 dbSNP
rs556082514 409 dbSNP
rs1491143045 410 dbSNP
rs1244582388 411 dbSNP
rs886237364 413 dbSNP
rs1056979832 417 dbSNP
rs564701976 418 dbSNP
rs938555795 418 dbSNP
rs1383763695 420 dbSNP
rs1317376376 421 dbSNP
rs1444871607 422 dbSNP
rs1343287697 425 dbSNP
rs115469158 426 dbSNP
rs1270752504 427 dbSNP
rs969169136 439 dbSNP
rs189507276 450 dbSNP
rs143202286 451 dbSNP
rs1233605047 454 dbSNP
rs760527597 470 dbSNP
rs1553877 484 dbSNP
rs1035887365 485 dbSNP
rs1398619035 496 dbSNP
rs1161216415 498 dbSNP
rs914323295 504 dbSNP
rs576194745 506 dbSNP
rs1396421470 508 dbSNP
rs534159321 512 dbSNP
rs866649476 514 dbSNP
rs1405497869 517 dbSNP
rs1385664823 520 dbSNP
rs1318765807 524 dbSNP
rs1165029572 529 dbSNP
rs749345608 538 dbSNP
rs1438637279 539 dbSNP
rs1231813140 555 dbSNP
rs1373371903 557 dbSNP
rs1181980856 565 dbSNP
rs770138848 566 dbSNP
rs1023021238 573 dbSNP
rs775669443 580 dbSNP
rs1440040115 583 dbSNP
rs1265932466 592 dbSNP
rs887512962 598 dbSNP
rs1269179122 607 dbSNP
rs571686197 610 dbSNP
rs186407636 613 dbSNP
rs993309821 615 dbSNP
rs1212441851 616 dbSNP
rs148340715 620 dbSNP
rs1468576410 625 dbSNP
rs1180499431 626 dbSNP
rs1294419042 627 dbSNP
rs1470959578 628 dbSNP
rs1040243362 632 dbSNP
rs1238159095 637 dbSNP
rs1459802017 652 dbSNP
rs1167064355 654 dbSNP
rs1396761414 655 dbSNP
rs1387374030 660 dbSNP
rs1328307236 662 dbSNP
rs943232966 666 dbSNP
rs1444712423 669 dbSNP
rs1028568744 671 dbSNP
rs1355269563 672 dbSNP
rs910474013 674 dbSNP
rs995465831 683 dbSNP
rs868067847 689 dbSNP
rs115965992 692 dbSNP
rs1194672313 696 dbSNP
rs1280194871 697 dbSNP
rs1241333750 698 dbSNP
rs549298525 699 dbSNP
rs1270285990 706 dbSNP
rs1439176143 711 dbSNP
rs143353283 713 dbSNP
rs914629224 716 dbSNP
rs1321459704 721 dbSNP
rs1474131143 731 dbSNP
rs372167223 732 dbSNP
rs1404275807 735 dbSNP
rs988935238 736 dbSNP
rs956145355 737 dbSNP
rs781481373 739 dbSNP
rs1461433857 742 dbSNP
rs779696831 742 dbSNP
rs1411837207 746 dbSNP
rs1308920991 747 dbSNP
rs1375098111 754 dbSNP
rs1417472623 755 dbSNP
rs757558487 756 dbSNP
rs1056967768 768 dbSNP
rs1295508923 774 dbSNP
rs1002734824 786 dbSNP
rs1406860036 788 dbSNP
rs981586504 789 dbSNP
rs1470857605 791 dbSNP
rs1375451412 792 dbSNP
rs536452039 812 dbSNP
rs547491331 816 dbSNP
rs1212670838 827 dbSNP
rs1256670762 832 dbSNP
rs1427847568 834 dbSNP
rs1023248865 842 dbSNP
rs1044371344 844 dbSNP
rs1476406767 847 dbSNP
rs1169345933 853 dbSNP
rs947288135 860 dbSNP
rs892756758 876 dbSNP
rs1433111411 878 dbSNP
rs1052798621 882 dbSNP
rs934389284 885 dbSNP
rs1006285519 890 dbSNP
rs1271488671 894 dbSNP
rs951768059 897 dbSNP
rs1488072835 903 dbSNP
rs1285264939 904 dbSNP
rs1228439913 907 dbSNP
rs986923538 908 dbSNP
rs1345278897 913 dbSNP
rs1225712324 914 dbSNP
rs1342895590 918 dbSNP
rs1236127107 920 dbSNP
rs1256338160 922 dbSNP
rs1274346233 926 dbSNP
rs1222823646 930 dbSNP
rs1263717650 941 dbSNP
rs1465296929 943 dbSNP
rs527258847 948 dbSNP
rs138346232 952 dbSNP
rs974263675 960 dbSNP
rs1397958905 969 dbSNP
rs891846844 970 dbSNP
rs1453434454 971 dbSNP
rs76316879 972 dbSNP
rs544653260 980 dbSNP
rs1387690739 981 dbSNP
rs1402100039 982 dbSNP
rs1324630471 984 dbSNP
rs1301476896 985 dbSNP
rs1368197082 985 dbSNP
rs1442622701 985 dbSNP
rs777762354 985 dbSNP
rs1262288005 989 dbSNP
rs1026416285 990 dbSNP
rs1175171666 991 dbSNP
rs993216611 992 dbSNP
rs1329765138 997 dbSNP
rs1213061553 1000 dbSNP
rs963005837 1003 dbSNP
rs1193012808 1004 dbSNP
rs1467233169 1004 dbSNP
rs1015987555 1017 dbSNP
rs1475266813 1018 dbSNP
rs1243073347 1021 dbSNP
rs1414738645 1028 dbSNP
rs982826906 1034 dbSNP
rs575923006 1044 dbSNP
rs1440978564 1046 dbSNP
rs961062521 1048 dbSNP
rs1035136141 1051 dbSNP
rs1262579859 1056 dbSNP
rs1372092682 1058 dbSNP
rs901600054 1069 dbSNP
rs1040192494 1074 dbSNP
rs1350922629 1082 dbSNP
rs1232578674 1087 dbSNP
rs905653701 1093 dbSNP
rs1216748070 1099 dbSNP
rs1360941030 1106 dbSNP
rs1007438423 1109 dbSNP
rs1332273668 1117 dbSNP
rs758946707 1135 dbSNP
rs745343816 1139 dbSNP
rs1254390001 1142 dbSNP
rs1022809757 1144 dbSNP
rs1187718661 1157 dbSNP
rs1011877172 1162 dbSNP
rs1270557707 1167 dbSNP
rs1426091759 1174 dbSNP
rs1432453620 1176 dbSNP
rs562811705 1180 dbSNP
rs1460121104 1181 dbSNP
rs1309518870 1186 dbSNP
rs1370807643 1187 dbSNP
rs1053188112 1191 dbSNP
rs554049781 1207 dbSNP
rs542414972 1212 dbSNP
rs753236541 1213 dbSNP
rs934379996 1224 dbSNP
rs1228877095 1229 dbSNP
rs914556876 1230 dbSNP
rs1053063706 1236 dbSNP
rs934714305 1242 dbSNP
rs1050763217 1251 dbSNP
rs144591279 1256 dbSNP
rs1202553715 1259 dbSNP
rs981565290 1260 dbSNP
rs1276990727 1266 dbSNP
rs1483509052 1270 dbSNP
rs1169098279 1271 dbSNP
rs1409906091 1278 dbSNP
rs948916005 1293 dbSNP
rs921403220 1295 dbSNP
rs1255925712 1299 dbSNP
rs1471923012 1301 dbSNP
rs553943703 1326 dbSNP
rs1416002362 1353 dbSNP
rs916129316 1355 dbSNP
rs1163886909 1372 dbSNP
rs754500824 1384 dbSNP
rs974231076 1387 dbSNP
rs1426168457 1394 dbSNP
rs985035103 1396 dbSNP
rs1390330751 1403 dbSNP
rs952409882 1413 dbSNP
rs181896594 1438 dbSNP
rs960777810 1442 dbSNP
rs1448642878 1444 dbSNP
rs1288167756 1449 dbSNP
rs971726598 1451 dbSNP
rs753368622 1454 dbSNP
rs1299939102 1455 dbSNP
rs190154152 1459 dbSNP
rs558178494 1461 dbSNP
rs1278598735 1462 dbSNP
rs888979522 1464 dbSNP
rs1444540046 1466 dbSNP
rs1022778652 1482 dbSNP
rs538281111 1485 dbSNP
rs1485179470 1492 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 729627.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000383163.2 | 3UTR | AUAUACAUAUAUAUAUGU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000383163.2 | 3UTR | UACAUAUACAUAUAUAUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000383163.2 | 3UTR | UACAUAUACAUAUAUAUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla -0.608 1.4e-2 -0.445 6.4e-2 13 Click to see details
GSE28544 Breast cancer 0.194 1.8e-1 0.207 1.7e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
LIHC 0.411 0.03 0.539 0.01 21 Click to see details
HNSC -0.417 0.07 -0.108 0.36 14 Click to see details
BRCA 0.426 0.07 0.422 0.08 13 Click to see details
STAD -0.461 0.08 0.175 0.3 11 Click to see details
BLCA -0.43 0.2 -0.143 0.39 6 Click to see details
LUSC 0.132 0.31 0.317 0.11 17 Click to see details
KICH -0.232 0.35 0.250 0.34 5 Click to see details
THCA -0.027 0.45 0.305 0.07 25 Click to see details
PAAD 0.037 0.49 0.125 0.46 3 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
UCEC 0.007 0.49 0.029 0.48 6 Click to see details
46 hsa-miR-1284 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT035831 PRRC2B proline rich coiled-coil 2B 1 1
MIRT079621 DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 2 2
MIRT149901 LDLR low density lipoprotein receptor 2 2
MIRT182786 TOR1AIP2 torsin 1A interacting protein 2 2 2
MIRT188827 TMTC3 transmembrane and tetratricopeptide repeat containing 3 2 2
MIRT198187 EIF4A1 eukaryotic translation initiation factor 4A1 3 1
MIRT245472 ARID5B AT-rich interaction domain 5B 2 2
MIRT252245 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2 6
MIRT269363 WEE1 WEE1 G2 checkpoint kinase 2 2
MIRT320406 HOXA9 homeobox A9 2 4
MIRT474722 KIF13A kinesin family member 13A 2 6
MIRT497926 BTG1 BTG anti-proliferation factor 1 2 2
MIRT504264 C1orf147 chromosome 1 open reading frame 147 2 4
MIRT520449 TSPAN2 tetraspanin 2 2 4
MIRT524092 DNAJB14 DnaJ heat shock protein family (Hsp40) member B14 2 4
MIRT528639 SENP6 SUMO1/sentrin specific peptidase 6 2 2
MIRT537385 FGF2 fibroblast growth factor 2 2 2
MIRT538902 BRI3BP BRI3 binding protein 2 2
MIRT542095 KCNK10 potassium two pore domain channel subfamily K member 10 2 6
MIRT543976 PRR23A proline rich 23A 2 2
MIRT549625 ADCYAP1 adenylate cyclase activating polypeptide 1 2 4
MIRT554298 SIPA1L2 signal induced proliferation associated 1 like 2 2 2
MIRT554872 RCAN2 regulator of calcineurin 2 2 2
MIRT567623 FAM210A family with sequence similarity 210 member A 2 2
MIRT571137 TTC33 tetratricopeptide repeat domain 33 2 2
MIRT576361 Pxdn peroxidasin 2 2
MIRT611088 PHF8 PHD finger protein 8 2 2
MIRT612380 TCTE1 t-complex-associated-testis-expressed 1 2 4
MIRT613725 MTPN myotrophin 2 2
MIRT614627 YAE1D1 Yae1 domain containing 1 2 2
MIRT615818 KIAA1549L KIAA1549 like 2 2
MIRT620949 TBCK TBC1 domain containing kinase 2 2
MIRT622339 SCN4A sodium voltage-gated channel alpha subunit 4 2 2
MIRT623219 MTA3 metastasis associated 1 family member 3 2 4
MIRT628932 SLC1A4 solute carrier family 1 member 4 2 2
MIRT632121 FKBP9 FK506 binding protein 9 2 2
MIRT635877 COX17 COX17, cytochrome c oxidase copper chaperone 2 2
MIRT636485 IKBKG inhibitor of nuclear factor kappa B kinase subunit gamma 2 2
MIRT653097 SRSF7 serine and arginine rich splicing factor 7 2 2
MIRT655048 PKN2 protein kinase N2 2 2
MIRT686946 SFT2D3 SFT2 domain containing 3 2 2
MIRT692724 INPP5B inositol polyphosphate-5-phosphatase B 2 2
MIRT697282 ZNF800 zinc finger protein 800 2 2
MIRT698995 SPAG9 sperm associated antigen 9 2 2
MIRT704462 CRNKL1 crooked neck pre-mRNA splicing factor 1 2 2
MIRT715163 FIG4 FIG4 phosphoinositide 5-phosphatase 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-1284 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-1284 Sorafenib 216239 NSC747971 approved sensitive High Hepatocellular Carcinoma tissue
hsa-miR-1284 Vincristine 5978 approved sensitive Low Gastric Cancer cell line (SGC-7901)
hsa-miR-1284 Cisplatin 5460033 NSC119875 approved sensitive Low Cervical Cancer cell line (HeLa, SiHa)
hsa-miR-1284 Cisplatin + Decitabine sensitive High Non-Small Cell Lung Cancer cell line (A549)
hsa-mir-1284 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1284 Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1284 Gefitinib 123631 NSC715055 approved sensitive cell line (PC9)
hsa-miR-1284 Osimertinib 71496458 NSC779217 approved sensitive cell line (HCC827)
hsa-miR-1284 Osimertinib 71496458 NSC779217 approved sensitive cell line (PC9)
hsa-miR-1284 Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM17)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM47)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM43)
hsa-miR-1284 Vemurafenib 42611257 NSC761431 approved sensitive cell line (LM11)
hsa-miR-1284 Tamoxifen 2733525 NSC180973 approved sensitive cell line (LCC2)
hsa-miR-1284 4-Hydroxytamoxifen+Tamoxifen resistant cell line (LY2)
hsa-miR-1284 Pegylated interferon alpha+Ribavirin sensitive tissue (chronic hepatitis C)
hsa-miR-1284 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-1284 Neoadjuvant chemotherapy resistant tissue (breast cancer)
hsa-miR-1284 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-1284 Paclitaxel/Docetaxel/Vinorelbine/Doxorubicin/Etoposide sensitive cell line (Bads-200)

Error report submission