pre-miRNA Information
pre-miRNA hsa-mir-190b   
Genomic Coordinates chr1: 154193665 - 154193743
Description Homo sapiens miR-190b stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-190b
Sequence 11| UGAUAUGUUUGAUAUUGGGUU |31
Evidence Not_experimental
Experiments
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol CSDE1   
Synonyms D1S155E, UNR
Description cold shock domain containing E1
Transcript NM_001007553   
Other Transcripts NM_001130523 , NM_007158   
Expression
Putative miRNA Targets on CSDE1
3'UTR of CSDE1
(miRNA target sites are highlighted)
>CSDE1|NM_001007553|3'UTR
   1 CCACATCCACAAAGCACACCATTAATCCACTATGATCAAGTTGGGGGGAATCTGGTGAAGGGTTCTGAATATCTCCCTCT
  81 TCATCCCTCCCGAAATCTGGAATACTTATTCTATTGAGCTATTACACCAGTTTTAACACCTTCCTCGTGTTATGTTTAAA
 161 AAAATAAATAAATTTAAGAAAACCATTTTAAATAATGCACAGTTGCAGCCTGGAAAAACTTAAGGTGGCGCCTTATAGTA
 241 TCAATTTTAGGAGCTTTATTTGGTGCATTTAACGCAACTGGTAATTGCAGAATCCACTTTGCCTGTGTAAGTGAAAAATA
 321 TAGACTGTTATCTTGTTGGCCCTATGAAATTCTGCACTTTTCATTATATACTCTACCTTCATTAATTACTTCTGGCAAGA
 401 TGTTCTGCCTTAGCACTCAGTTGCATTCTTTTCCTTTTTCTTCCTGTTCATTATGCTTTAATTCTGAGGACCATATGAGG
 481 GTAGAATATATTATCTTTTAAAAATTACAAAAATTTGTATAGGCAAACCATTTCTTAAAGTTGATGGCCAAATTTTAAAA
 561 TGTTATTTTTCATATCATTTATAATCTTGTCACAATCCACTTAAAGAAGTTTGGTTATATTTCAGTGAAAATTTTCTTCC
 641 AGAGTAGGTTTTTTTTCGTGGGTTGGGGGGTAACTTTACTACAATTAGTAAGTATGGTGCAGAATTTCATGCAAATGAGG
 721 AGTGCCAGCAGTGTGATAATTTAAACATATTTAAACAAAAACAAAAAAAATGAATGCACAAACTTGCTGCTGCTTAGATC
 801 ACTGCAGCTTCTAGGACCCGGTTTCTTTTACTGATTTAAAAACAAAACAAAAAAAAATAAAAAAGTTGTGCCTGAAATGA
 881 ATCTTGTTTTTTTTTATAAGTAGCCGCCTGGTTACTGTGTCCTGTAAAATACAGACACTTGACCCTTGGTGTAGCTTCTG
 961 TTCAACTTTATATCACGGGAATGGATGGGTCTGATTTCTTGGCCCTCTTCTTGAATTGGCCATATACAGGGTCCCTGGCC
1041 AGTGGACTGAAGGCTTTGTCTAAGATGACAAGGGTCAGCTCAGGGGATGTGGGGGAGGGCGGTTTTATCTTCCCCCTTGT
1121 CGTTTGAGGTTTTGATCTCTGGGTAAAGAGGCCGTTTATCTTTGTAAACACGAAACATTTTTGCTTTCTCCAGTTTTCTG
1201 TTAATGGCGAAAGAATGGAAGCGAATAAAGTTTTACTGATTTTTGAGACACTAGCAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' uuggGUUAUAGUUUGUAUAGu 5'
              :||| |:||||||||: 
Target 5' gtgaTAAT-TTAAACATATTt 3'
733 - 752 148.00 -8.40
2
miRNA  3' uugggUUAUAGUUUGUAUAGu 5'
               |: :| :||:||||: 
Target 5' atatgAGGGTAGAATATATTa 3'
473 - 493 120.00 -5.20
3
miRNA  3' uuggguuauaguuuGUAUAGu 5'
                        |||||| 
Target 5' aaaatgttatttttCATATCa 3'
557 - 577 120.00 -9.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1202429 1210 ClinVar
COSN26972009 14 COSMIC
COSN26972006 43 COSMIC
COSN30182540 54 COSMIC
COSN30147120 57 COSMIC
COSN30521483 79 COSMIC
COSN26972014 80 COSMIC
COSN30447870 91 COSMIC
COSN30123779 92 COSMIC
COSN31522732 102 COSMIC
COSN18724860 158 COSMIC
COSN31595819 171 COSMIC
COSN27906568 401 COSMIC
COSN16183001 473 COSMIC
COSN26641552 623 COSMIC
COSN31551237 640 COSMIC
COSN31536082 672 COSMIC
COSN5999415 741 COSMIC
COSN31562594 743 COSMIC
COSN26574106 771 COSMIC
COSN15652873 848 COSMIC
COSN31513893 853 COSMIC
COSN26409972 865 COSMIC
COSN31563579 907 COSMIC
COSN28123271 1026 COSMIC
COSN24297534 1100 COSMIC
COSN31516857 1188 COSMIC
COSN31484342 1223 COSMIC
COSN16810712 1254 COSMIC
rs10489525 1191 GWAS
rs8453 1191 GWAS
rs926938 1191 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs374095550 1 dbSNP
rs9724612 9 dbSNP
rs369948708 10 dbSNP
rs1181709750 12 dbSNP
rs183844328 12 dbSNP
rs1193459648 19 dbSNP
rs1189224149 21 dbSNP
rs1801909 28 dbSNP
rs777289026 32 dbSNP
rs753260110 33 dbSNP
rs1432985455 36 dbSNP
rs1322585894 42 dbSNP
rs1272676156 45 dbSNP
rs1226662164 46 dbSNP
rs766109129 47 dbSNP
rs755778971 48 dbSNP
rs770432178 49 dbSNP
rs750274957 51 dbSNP
rs9724613 52 dbSNP
rs1297785048 53 dbSNP
rs1388129426 55 dbSNP
rs1438639185 61 dbSNP
rs908473995 62 dbSNP
rs553300119 69 dbSNP
rs1047140469 71 dbSNP
rs930973617 91 dbSNP
rs9724614 92 dbSNP
rs191181816 100 dbSNP
rs994946001 104 dbSNP
rs748695142 109 dbSNP
rs552011956 113 dbSNP
rs987012996 117 dbSNP
rs1202388993 121 dbSNP
rs1245493445 123 dbSNP
rs1452782405 131 dbSNP
rs968012820 133 dbSNP
rs1488480090 134 dbSNP
rs1020549514 136 dbSNP
rs911582753 137 dbSNP
rs865798017 141 dbSNP
rs6851 147 dbSNP
rs1332179977 151 dbSNP
rs1414728363 154 dbSNP
rs957370625 158 dbSNP
rs1407158894 163 dbSNP
rs1321741201 164 dbSNP
rs1349356786 174 dbSNP
rs753894875 178 dbSNP
rs1034353619 198 dbSNP
rs989352745 202 dbSNP
rs1445708801 205 dbSNP
rs36070559 209 dbSNP
rs1284443377 210 dbSNP
rs569613546 219 dbSNP
rs1226257193 230 dbSNP
rs1288601563 230 dbSNP
rs143187563 236 dbSNP
rs1199856437 247 dbSNP
rs1240512846 253 dbSNP
rs1350288016 254 dbSNP
rs1456724783 260 dbSNP
rs1178339919 262 dbSNP
rs1278224330 263 dbSNP
rs1473929535 271 dbSNP
rs529640711 272 dbSNP
rs935170340 273 dbSNP
rs907314839 274 dbSNP
rs1466173377 280 dbSNP
rs1172759399 281 dbSNP
rs565950090 296 dbSNP
rs1322966479 300 dbSNP
rs1334653078 304 dbSNP
rs1459977562 309 dbSNP
rs1342032176 318 dbSNP
rs546876074 321 dbSNP
rs1391074212 323 dbSNP
rs370293634 323 dbSNP
rs1013433236 331 dbSNP
rs1340617483 332 dbSNP
rs764771811 340 dbSNP
rs971862057 342 dbSNP
rs1047014818 344 dbSNP
rs1279839554 352 dbSNP
rs1024271094 354 dbSNP
rs931256212 361 dbSNP
rs991435087 368 dbSNP
rs1175326987 370 dbSNP
rs898153119 371 dbSNP
rs528690599 373 dbSNP
rs1157019452 376 dbSNP
rs1478197616 381 dbSNP
rs1247262100 392 dbSNP
rs376078442 397 dbSNP
rs1465094686 399 dbSNP
rs1173071583 402 dbSNP
rs1027855617 403 dbSNP
rs546046078 416 dbSNP
rs1412492103 421 dbSNP
rs1466768857 422 dbSNP
rs1269585140 423 dbSNP
rs942427762 424 dbSNP
rs1333108211 428 dbSNP
rs1360689446 437 dbSNP
rs1401457861 444 dbSNP
rs185872129 444 dbSNP
rs995465331 447 dbSNP
rs1208970491 451 dbSNP
rs1227392961 453 dbSNP
rs1316642109 455 dbSNP
rs1199034790 471 dbSNP
rs1282579432 473 dbSNP
rs1279887581 479 dbSNP
rs1488780842 484 dbSNP
rs1219063467 492 dbSNP
rs1261190637 492 dbSNP
rs897998418 506 dbSNP
rs1199513211 508 dbSNP
rs563584650 519 dbSNP
rs1476919622 529 dbSNP
rs1171853473 535 dbSNP
rs1380665765 536 dbSNP
rs1008660858 537 dbSNP
rs1473897023 538 dbSNP
rs946245432 547 dbSNP
rs755356304 551 dbSNP
rs1386797888 561 dbSNP
rs1050112139 565 dbSNP
rs1333269694 566 dbSNP
rs913435872 572 dbSNP
rs1274824556 581 dbSNP
rs1438739811 591 dbSNP
rs1354843464 593 dbSNP
rs1242642350 595 dbSNP
rs990360457 595 dbSNP
rs957652301 605 dbSNP
rs1210436211 606 dbSNP
rs1034301199 609 dbSNP
rs1449850633 612 dbSNP
rs1434635332 617 dbSNP
rs1053711100 632 dbSNP
rs1343728064 636 dbSNP
rs1441272520 637 dbSNP
rs1156633272 648 dbSNP
rs1416012518 652 dbSNP
rs1425726155 654 dbSNP
rs935205831 656 dbSNP
rs1164565472 657 dbSNP
rs1172972107 658 dbSNP
rs980090099 659 dbSNP
rs1385644699 662 dbSNP
rs923816075 663 dbSNP
rs542289182 666 dbSNP
rs1249362568 671 dbSNP
rs1307350416 678 dbSNP
rs1316620327 684 dbSNP
rs574875543 686 dbSNP
rs1245776775 688 dbSNP
rs1267351981 692 dbSNP
rs1354299952 697 dbSNP
rs1213022836 700 dbSNP
rs371539180 705 dbSNP
rs762842125 717 dbSNP
rs1013797229 720 dbSNP
rs886942022 722 dbSNP
rs982321654 723 dbSNP
rs752020623 735 dbSNP
rs1176477655 739 dbSNP
rs1249554601 745 dbSNP
rs1424093962 750 dbSNP
rs1189167037 751 dbSNP
rs1240040528 756 dbSNP
rs950189312 758 dbSNP
rs1313172303 762 dbSNP
rs1280191182 764 dbSNP
rs917312461 765 dbSNP
rs199596172 766 dbSNP
rs767793974 767 dbSNP
rs1027574515 771 dbSNP
rs373000705 771 dbSNP
rs374332374 771 dbSNP
rs991487651 771 dbSNP
rs370476917 772 dbSNP
rs560558972 779 dbSNP
rs553336786 781 dbSNP
rs771596885 783 dbSNP
rs1232690839 787 dbSNP
rs753534125 797 dbSNP
rs1449908466 800 dbSNP
rs1039364864 804 dbSNP
rs1359533445 811 dbSNP
rs1250601483 815 dbSNP
rs1009462604 819 dbSNP
rs1312138090 820 dbSNP
rs890250544 832 dbSNP
rs942396836 835 dbSNP
rs1432772504 837 dbSNP
rs1253589455 839 dbSNP
rs1392019898 843 dbSNP
rs1474594759 843 dbSNP
rs1028740158 844 dbSNP
rs541309766 848 dbSNP
rs577033305 856 dbSNP
rs1354350300 858 dbSNP
rs1466827578 858 dbSNP
rs557719829 858 dbSNP
rs61764383 858 dbSNP
rs893478100 858 dbSNP
rs1427457220 859 dbSNP
rs890836948 862 dbSNP
rs1342430097 863 dbSNP
rs1183266243 865 dbSNP
rs1216766429 865 dbSNP
rs1294725849 865 dbSNP
rs1312583780 869 dbSNP
rs902413837 870 dbSNP
rs1046251132 873 dbSNP
rs949238241 881 dbSNP
rs1264752097 883 dbSNP
rs758716380 884 dbSNP
rs1486997920 886 dbSNP
rs1185309494 890 dbSNP
rs1419354479 891 dbSNP
rs916382276 893 dbSNP
rs1178776942 896 dbSNP
rs61764384 896 dbSNP
rs79884428 896 dbSNP
rs746214615 897 dbSNP
rs1362574445 899 dbSNP
rs1050870324 900 dbSNP
rs1288235166 905 dbSNP
rs750470887 906 dbSNP
rs1014209439 910 dbSNP
rs913395670 919 dbSNP
rs1054581411 922 dbSNP
rs1287658105 924 dbSNP
rs1209268444 932 dbSNP
rs1484307045 933 dbSNP
rs558730735 934 dbSNP
rs575288337 938 dbSNP
rs1226724533 960 dbSNP
rs536802381 963 dbSNP
rs936239511 965 dbSNP
rs1454079558 968 dbSNP
rs1159501072 970 dbSNP
rs1382346206 970 dbSNP
rs765361648 972 dbSNP
rs1158545849 974 dbSNP
rs1315031226 978 dbSNP
rs987692811 981 dbSNP
rs954865984 984 dbSNP
rs1029126167 987 dbSNP
rs1229115252 1004 dbSNP
rs1355127225 1005 dbSNP
rs1370005467 1007 dbSNP
rs1447171875 1013 dbSNP
rs1065634 1022 dbSNP
rs549309151 1024 dbSNP
rs1348182727 1027 dbSNP
rs1222837622 1028 dbSNP
rs535880949 1041 dbSNP
rs1322968500 1043 dbSNP
rs1801910 1044 dbSNP
rs12254 1047 dbSNP
rs1412745034 1049 dbSNP
rs957745618 1051 dbSNP
rs971424750 1053 dbSNP
rs917276899 1056 dbSNP
rs565317127 1061 dbSNP
rs1468332214 1068 dbSNP
rs983546722 1071 dbSNP
rs950891889 1074 dbSNP
rs999577626 1078 dbSNP
rs1298700046 1079 dbSNP
rs771399801 1084 dbSNP
rs1352261824 1085 dbSNP
rs1025461761 1087 dbSNP
rs1414663326 1089 dbSNP
rs1407104926 1091 dbSNP
rs1046734235 1094 dbSNP
rs1013418878 1096 dbSNP
rs1424014350 1099 dbSNP
rs546962160 1106 dbSNP
rs1466072223 1107 dbSNP
rs1333189337 1109 dbSNP
rs962593849 1114 dbSNP
rs1333746222 1115 dbSNP
rs775482433 1116 dbSNP
rs1416774137 1119 dbSNP
rs895002638 1120 dbSNP
rs1018213754 1121 dbSNP
rs1380742504 1122 dbSNP
rs1230866619 1125 dbSNP
rs1271836178 1125 dbSNP
rs1334823056 1127 dbSNP
rs1186233786 1134 dbSNP
rs528797826 1144 dbSNP
rs1054857672 1145 dbSNP
rs937457937 1148 dbSNP
rs1195740083 1149 dbSNP
rs920662157 1154 dbSNP
rs767399896 1156 dbSNP
rs759292396 1164 dbSNP
rs760471215 1168 dbSNP
rs1229688334 1175 dbSNP
rs1185984352 1179 dbSNP
rs1417235805 1184 dbSNP
rs1009975671 1188 dbSNP
rs1334403500 1189 dbSNP
rs8453 1191 dbSNP
rs1409107775 1192 dbSNP
rs1334419733 1193 dbSNP
rs1054524283 1198 dbSNP
rs552741102 1200 dbSNP
rs1412538270 1204 dbSNP
rs1292183518 1209 dbSNP
rs6694035 1210 dbSNP
rs1272380613 1213 dbSNP
rs1337867699 1216 dbSNP
rs1214281651 1220 dbSNP
rs1279777412 1221 dbSNP
rs927508713 1225 dbSNP
rs1352130555 1226 dbSNP
rs1208974725 1227 dbSNP
rs1044648601 1228 dbSNP
rs1256952564 1230 dbSNP
rs9724615 1240 dbSNP
rs917242694 1241 dbSNP
rs1195789831 1245 dbSNP
rs1371213463 1246 dbSNP
rs1474964933 1247 dbSNP
rs1173018655 1248 dbSNP
rs769343900 1250 dbSNP
rs113010659 1252 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 7812.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1
miRNA  3' uuggguuauaguuuGUAUAGu 5'
                        |||||| 
Target 5' -------uauuuuuCAUAUCa 3'
1 - 14
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM4903833
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_a
Location of target site NM_001242892 | 3UTR | UUCUGAGGACCAUAUGAGGGUAGAAUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUCUUGUCACAAUCCACUUAAAGAAGUUUGGUUAUAUUUCAGUGAAAAUUUUCUUCCAGAGUAGGUUUUUUUUCGUGGGUUGGGGGGUAACUUUACUACAAUUAGUAAGUAUGGUGCAGAAUUUCAUGCAAAUGAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM4903834
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_b
Location of target site NM_001242892 | 3UTR | UUUAAUUCUGAGGACCAUAUGAGGGUAGAAUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUC
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 3 for dataset GSM4903835
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / CTL_TD_21_c
Location of target site NM_001242892 | 3UTR | AUUCUGAGGACCAUAUGAGGGUAGAAUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUCUUGUCACAAUCCACUUAAAGAAGUUUGGUUAUAUUUCAGUGAAAAUUUUCUUCCAGAGUAGGUUUUUUUUCGUGGGUUGGGGGGUAACUUUACUACAAUUAGUAAGUAUGGUGCAGAAUUUCAUGCAAAUGAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 4 for dataset GSM4903836
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_a
Location of target site NM_001242892 | 3UTR | AAUUCUGAGGACCAUAUGAGGGUAGAAUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUCUUGUCACAAUCCACUUAAAGAAGUUUGGUUAUAUUUCAGUGAAAAUUUUCUUCCAGAGUAGGUUUUUUUUCGUGGGUUGGGGGGUAACUUUACUACAAUUAGUAAGUAUGGUGCAGAAUUUCAUGCAAAUGAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 5 for dataset GSM4903837
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_b
Location of target site NM_001130523 | 3UTR | AUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUCUUGUCACAAUCCACUUAAAGAAGUUUGGUUAUAUUUCAGUGAAAAUUUUCUUCCAGAGUAGGUUUUUUUUCGUGGGUUGGGGGGUAACUUUACUACAAUUAGUAAGUAUGGUGCAGAAUUUCAUGCAAAUGAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 6 for dataset GSM4903838
Method / RBP HITS-CLIP / AGO
Cell line / Condition Dermal fibroblasts / 124_TD_21_c
Location of target site NM_001242892 | 3UTR | AGGACCAUAUGAGGGUAGAAUAUAUUAUCUUUUAAAAAUUACAAAAAUUUGUAUAGGCAAACCAUUUCUUAAAGUUGAUGGCCAAAUUUUAAAAUGUUAUUUUUCAUAUCAUUUAUAAUCUUGUCACAAUCCACUUAAAGAAGUUUGGUUAUAUUUCAGUGAAAAUUUUCUUCCAGAGUAGGUUUUUUUUCGUGGGUUGGGGGGUAACUUUACUACAAUUAGUAAGUAUGGUGCAGAAUUUCAUGCAAAUGAGGA
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Accession Series GSE161239
CLIP-seq Viewer Link
CLIP-seq Support 7 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000339438.6 | 3UTR | UAUUUUUCAUAUCAUUUAUAAUCUU
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28544 Breast cancer -0.677 1.4e-4 -0.615 6.9e-4 24 Click to see details
GSE28260 Renal cortex and medulla 0.564 2.2e-2 0.665 6.6e-3 13 Click to see details
GSE19350 CNS germ cell tumors -0.503 4.8e-2 -0.058 4.3e-1 12 Click to see details
GSE19536 Breast cancer -0.159 5.7e-2 -0.152 6.6e-2 100 Click to see details
GSE19783 ER- ER- breast cancer -0.145 1.0e-1 -0.114 1.6e-1 79 Click to see details
GSE38226 Liver fibrosis -0.255 1.3e-1 -0.381 4.4e-2 21 Click to see details
GSE21687 Ependynoma primary tumors -0.131 1.5e-1 -0.304 7.3e-3 64 Click to see details
GSE35602 Colorectal cancer stromal tissue -0.211 1.6e-1 -0.102 3.1e-1 25 Click to see details
GSE42095 Differentiated embryonic stem cells -0.197 1.8e-1 -0.177 2.1e-1 23 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.142 2.5e-1 0.160 2.2e-1 25 Click to see details
GSE15076 Monocyte-derived dendritic cells 0.298 2.6e-1 0.357 2.2e-1 7 Click to see details
GSE17498 Multiple myeloma 0.085 3.0e-1 0.118 2.3e-1 40 Click to see details
GSE32688 Pancreatic cancer -0.068 3.6e-1 0.018 4.6e-1 32 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis -0.081 3.7e-1 -0.448 2.4e-2 20 Click to see details
GSE19783 ER+ ER+ breast cancer 0.068 3.9e-1 0.066 3.9e-1 20 Click to see details
GSE26953 Aortic valvular endothelial cells -0.011 4.8e-1 -0.054 4.0e-1 24 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
BRCA -0.264 0.01 -0.263 0.01 72 Click to see details
HNSC 0.436 0.02 0.432 0.02 23 Click to see details
THCA -0.277 0.1 -0.203 0.17 24 Click to see details
UCEC -0.324 0.12 -0.286 0.15 15 Click to see details
ESCA 0.631 0.18 0.400 0.3 4 Click to see details
LUSC 0.159 0.26 0.237 0.16 19 Click to see details
KIRP -0.289 0.26 -0.357 0.22 7 Click to see details
CHOL 0.431 0.28 0.400 0.3 4 Click to see details
KIRC -0.138 0.33 -0.286 0.17 13 Click to see details
LIHC 0.101 0.35 0.075 0.38 18 Click to see details
KICH -0.217 0.36 -0.100 0.44 5 Click to see details
STAD -0.189 0.38 -0.100 0.44 5 Click to see details
LUAD 0.121 0.39 0.214 0.31 8 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
PRAD -0.041 0.43 -0.118 0.3 23 Click to see details
60 hsa-miR-190b Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT054581 IGF1 insulin like growth factor 1 4 1
MIRT066966 ATXN7L3B ataxin 7 like 3B 2 2
MIRT192449 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT250414 TNRC6A trinucleotide repeat containing 6A 2 2
MIRT306294 KLHL24 kelch like family member 24 2 2
MIRT355845 SGMS2 sphingomyelin synthase 2 2 4
MIRT437770 MTMR6 myotubularin related protein 6 1 1
MIRT437771 MTMR6 myotubularin related protein 6 1 1
MIRT437772 Mtmr6 myotubularin related protein 6 1 1
MIRT444672 CDKL2 cyclin dependent kinase like 2 2 2
MIRT446389 PCDHB11 protocadherin beta 11 2 2
MIRT446634 SDC3 syndecan 3 2 2
MIRT449410 TRIM5 tripartite motif containing 5 2 2
MIRT449560 GPC5 glypican 5 2 2
MIRT469928 PTPRJ protein tyrosine phosphatase, receptor type J 2 6
MIRT473736 MAP3K9 mitogen-activated protein kinase kinase kinase 9 2 2
MIRT474210 LDHA lactate dehydrogenase A 2 2
MIRT474583 KLF6 Kruppel like factor 6 2 2
MIRT476732 FOXN2 forkhead box N2 2 2
MIRT478455 DAB2 DAB2, clathrin adaptor protein 2 2
MIRT495327 ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 2 4
MIRT498615 MTRNR2L10 MT-RNR2-like 10 2 12
MIRT501734 OVOL1 ovo like transcriptional repressor 1 2 2
MIRT501849 MTRNR2L8 MT-RNR2-like 8 2 14
MIRT504678 CYGB cytoglobin 2 4
MIRT506517 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 6
MIRT507984 BCL2L13 BCL2 like 13 2 4
MIRT508444 ZNF608 zinc finger protein 608 2 4
MIRT511366 IL6ST interleukin 6 signal transducer 2 4
MIRT520515 TRA2B transformer 2 beta homolog 2 2
MIRT524571 CALML4 calmodulin like 4 2 4
MIRT531896 INVS inversin 2 4
MIRT533916 TATDN2 TatD DNase domain containing 2 2 2
MIRT537503 FAM13B family with sequence similarity 13 member B 2 2
MIRT541689 CCDC160 coiled-coil domain containing 160 2 8
MIRT544419 ZNF460 zinc finger protein 460 2 4
MIRT544615 CSDE1 cold shock domain containing E1 2 2
MIRT545076 IL7R interleukin 7 receptor 2 2
MIRT545849 ZNF264 zinc finger protein 264 2 4
MIRT547436 MED4 mediator complex subunit 4 2 2
MIRT550157 ZNF223 zinc finger protein 223 2 4
MIRT553948 STAMBP STAM binding protein 2 2
MIRT554395 SERP1 stress associated endoplasmic reticulum protein 1 2 2
MIRT555667 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT564193 PM20D2 peptidase M20 domain containing 2 2 2
MIRT566792 MKL2 MKL1/myocardin like 2 2 2
MIRT566843 LRRC58 leucine rich repeat containing 58 2 2
MIRT572516 KIAA0232 KIAA0232 2 2
MIRT607428 NOTCH2NL notch 2 N-terminal like 2 10
MIRT627779 RAB30 RAB30, member RAS oncogene family 2 2
MIRT635159 ENO4 enolase family member 4 2 2
MIRT642159 ADCYAP1R1 ADCYAP receptor type I 3 2
MIRT646205 DUSP10 dual specificity phosphatase 10 2 2
MIRT657007 KCNMB4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 2 2
MIRT665817 TMEM161B transmembrane protein 161B 2 2
MIRT667488 MAP3K2 mitogen-activated protein kinase kinase kinase 2 2 2
MIRT707098 ZNF850 zinc finger protein 850 2 2
MIRT708719 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT735521 HUS1 HUS1 checkpoint clamp component 3 0
MIRT736644 AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-1 Anthocyanin NULL 145858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Caffeic acid NULL 689043 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Curcumin NULL 969516 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Ferulic acid NULL 445858 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Hesperidin NULL 10621 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-1 Quercetin NULL 5280343 Microarray apoE−/− mice 22253797 2012 down-regulated
miR-1 Galactose NULL 6036 Quantitative real-time PCR lens 22736950 2012 up-regulated
miR-1 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) NULL 8490 Microarray mouse brain 19270793 2009 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Quantitative real-time PCR myocardial differentiation of mouse ES cells 19521018 2009 down-regulated
miR-1 Sulfonyl-hydrazone-1 (SHZ) NULL NULL Quantitative real-time PCR Murine broblast-derived Induced pluripotent stem cells 21445862 2011 up-regulated
miR-1 Cocaine NULL 446220 Next-generation sequencing ventral striatum 21708909 2011 up-regulated
miR-1 Atorvastatin approved 60823 Quantitative real-time PCR Cardiomyocyte 23860036 2013 down-regualted
miR-1 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miR-1 Docosahexaenoic acid NULL 445580 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 Palmitic acid approved 985 Quantitative real-time PCR Caco-2 cells 24623846 2014 up-regulated
miR-1 17beta-estradiol (E2) approved 5757 Microarray MCF-7AKT breast cancer cells 19528081 2009 down-regulated
miR-1 Essential amino acids (EAA) NULL NULL Quantitative real-time PCR skeletal muscle of young adults 19828686 2009 up-regulated
miR-1 Hydrogen peroxide (H2O2) NULL 784 Quantitative real-time PCR Human umbilical vein endothelial cells 21527937 2011 down-regulated
miR-1 Trichostatin A (TSA) NULL 444732 Microarray apoptosis-resistant breast cancer cells 21971930 2011 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR acute promyelocytic leukemia 22072212 2012 up-regulated
miR-1 5-Fluorouracil approved 3385 Microarray CNE cells 22614822 2012 up-regulated
miR-1 Bicalutamide approved 2375 Microarray prostate 22674191 2012 up-regulated
miR-1 Arsenic trioxide approved 14888 Quantitative real-time PCR cardia 22889704 2012 up-regulated
miR-1 Perfluorooctane sulfonate NULL 74483 Microarray zebrafish embryos 20878907 2011 up-regulated
miR-1 Quinidine approved 441074 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 up-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR myocardial infarction (MI) rats 19775284 2009 down-regulated
miR-1 Tanshinone IIA NULL 164676 Quantitative real-time PCR post-infarction rat cardiomyocytes 21220930 2011 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 down-regulated
miR-1 Dexamethasone approved 5743 Microarray adrenals and granulosa cells 24205079 2014 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 up-regulated
miR-1 Thiourea (TU) NULL 737139 Quantitative real-time PCR skeletal muscle and heart 22142802 2012 down-regulated
miR-1 Isoproterenol approved 3779 Quantitative real-time PCR heart 22847192 2012 up-regulated
miR-190b Catechin approved 9064 Microarray apoE−/− mice 22253797 2012 up-regulated
miR-190b Atorvastatin approved 60823 Microarray PC3 prostate cancer cells 23936432 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-190b Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)

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