miRTarBase - #MIRT545261


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pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol TRIM36   
Synonyms HAPRIN, RBCC728, RNF98
Description tripartite motif containing 36
Transcript NM_018700   
Other Transcripts NM_001017397 , NM_001017398   
Expression
Putative miRNA Targets on TRIM36
3'UTR of TRIM36
(miRNA target sites are highlighted)		 
>TRIM36|NM_018700|3'UTR
   1 TTGAAACATCTGATGTGACTCAGGATAAAAACTGTAAACAAAGCAATGCCTTAGCGTTAACCTTCGTAACTAATTACATA
  81 TCGCTGAGTGTTCTGTCACCCCACTTGTGTTTGAGTATGATTCTTCTTGAAATACAGAAAATCTAAACAGCCTTGTGTCT
 161 TCATGTCGTTGTTCTGCCTTTCACAAATGATGAAAGTGAAGATGTTCTTTCCAAGTTAATACTGAAGTGGTTAACTTTGC
 241 AACTGGACTGTCTTTTACTTTATGTACAGGATATCTAATTTATTTCTGTCAGCTGGTGTTGCTGACACTTTCCTTATGGT
 321 GGGGGGGATACAAAAGTATTTATTATGATTCTCTTCTGTTTGACTTTTCATTTTTATATCATGTTTATGTCCTAAGAGAA
 401 GATATTTTTTAAATGCCTTATGGATAGGAATTAGTACTAAGCAATGTGTCTTGCATTTGTTTTCAATAGGAAAACAAAGT
 481 TCTAGATAGGTTAAAAGAAAAACACCATAAAAGTGGTAGTATATTTAAGTGGAAAATTATGTATTTTAAAGTGTGTAACT
 561 ATTAAAAATATATTGCCTGGAAAAGGAATACTACTGTTTTGTTTTGTTAAGACCACAAACTGTATTGCTAAGGACATTTT
 641 AAGAGTCTGCTTAGCCATAACACTCATTTAACAGCATGGGTAGTAAGCATGGTTTCTTGCAGAAAACACAAAGTTCTCAG
 721 CTAACACATTAAACTTCTCACTTTATATACTTTTTTTCAGAGAAATTTATCTTTAGTTTTTCTTATTCTGTGAAAATATT
 801 TGTTCTTATGTCAAAGAATTATTTTTCAGATATATTGGTAAAGATGGACTGATATTAAAAGTCATATTTATTCTTTTACC
 881 CCCTTACTGTGTTTTGTGATTTTCATTTTTGGCCCAATTATTACATATCAGGTTTTCCTGATTTATATTTACATGTTTGA
 961 AAAGTTCATTATATATTTTAGTAGCGTTACATATATTATAAATTTTTGTAACATTTAAATGTTCACTTATGTGGCATTTT
1041 CTGTTTCTCATTGGTAATAAGCATTTCTAATATAAGCAAGTAAAAATACAAATTTAATTACTTAGAAATGATAACTAAGA
1121 TCACAATGACTGTGTACCCTTTAAAATATCTTTTAATTTGAGGAATTACATTCTATCTAAATTGTGTGTCTGTTTTTGAA
1201 AGGTGTTGCTTTCAAGTAGGTGGTTTTTATTTAAAGTACTTATTTTTTTGAGGTTAAAATATTCAGAAACTACTTTTATG
1281 CATTGTAGCAGTAATCATTTATGGAATGCTTTTGACATGTTTTAACAGGGTAACCAAAACTTTTAGGCCTGTTTTTTTTG
1361 GTTGTCCTTGTTGTTATATTTTTAATGGAAATCTGTTACTCAGGCTGGTAGCATTAAATTAGCTTTTTACCCTCAACTCA
1441 AGTAGCAAATATCATGGAGAACTTCAGTGTTTAGCAGGCTGTTAATTTCCCATCTATGAATAGCACTTTATGATGTAGGC
1521 TAAACTAAGCAAATAATGCAGCGTTATGTGGATCATTATGCAATAAAGCTGCTAAAGTCACATTTGTGGTTGATACTCAA
1601 GCCTTGTACAAGCACATATGATGTAGACATTTTTAAATGTGAAGCTTTAACAGGAATAGGATAGCTGTTTCAAACCTTGT
1681 GCAATTGTAAATAAATTGTTTAGCTGTGTTTCTTTCATTTTTAATAAAAAATTAAAAAGAAAAAAAAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agUGGUAACGAUUU----CACGUUAa 5'
            :|::|| | |||    ||||||| 
Target 5' taGCTGTTTC-AAACCTTGTGCAATt 3'
 1662 - 1686 153.00 -9.02
2 
miRNA  3' agugGUAACGAUUU--CACGUUaa 5'
              :||| :||||  |||:||  
Target 5' tatgTATT-TTAAAGTGTGTAAct 3'
 538 - 560 123.00 -6.63
3 
miRNA  3' agUGGUA-ACGAUUUCA-CGUUaa 5'
            ||| |   || |||| ||||  
Target 5' ttACCCTCAACTCAAGTAGCAAat 3'
 1427 - 1450 108.00 -7.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30155795 16 COSMIC
COSN30124107 28 COSMIC
COSN14134700 44 COSMIC
COSN30538095 45 COSMIC
COSN167528 55 COSMIC
COSN30126416 62 COSMIC
COSN30577960 63 COSMIC
COSN30120785 66 COSMIC
COSN20050286 101 COSMIC
COSN31535827 143 COSMIC
COSN31523927 156 COSMIC
COSN8491726 235 COSMIC
COSN31517297 246 COSMIC
COSN31596593 256 COSMIC
COSN16449128 858 COSMIC
COSN18981915 1229 COSMIC
COSN31589504 1402 COSMIC
COSN31578741 1434 COSMIC
COSN30167071 1489 COSMIC
COSN31531250 1537 COSMIC
COSN28832336 1661 COSMIC
COSN27039307 1731 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1298844553 2 dbSNP
rs1290647542 4 dbSNP
rs1465003080 7 dbSNP
rs1057132373 8 dbSNP
rs781268866 10 dbSNP
rs367967198 12 dbSNP
rs1387997819 19 dbSNP
rs1187538208 20 dbSNP
rs763441687 21 dbSNP
rs566557539 25 dbSNP
rs772279565 27 dbSNP
rs752272921 33 dbSNP
rs999611752 39 dbSNP
rs375562920 40 dbSNP
rs1212818827 42 dbSNP
rs759893104 43 dbSNP
rs374355605 46 dbSNP
rs766744448 47 dbSNP
rs761020821 49 dbSNP
rs773799874 50 dbSNP
rs546997247 55 dbSNP
rs542986743 56 dbSNP
rs140117888 57 dbSNP
rs777302935 61 dbSNP
rs941277229 63 dbSNP
rs570735967 65 dbSNP
rs1481320325 66 dbSNP
rs1483041712 66 dbSNP
rs1197166885 70 dbSNP
rs35914047 70 dbSNP
rs1410499774 71 dbSNP
rs1261606675 77 dbSNP
rs550553267 82 dbSNP
rs931421716 83 dbSNP
rs1309020632 84 dbSNP
rs919968312 103 dbSNP
rs180859502 104 dbSNP
rs561853026 114 dbSNP
rs951159964 116 dbSNP
rs1215681270 117 dbSNP
rs1297081699 119 dbSNP
rs536729589 120 dbSNP
rs1339542820 123 dbSNP
rs529152577 126 dbSNP
rs1203963767 133 dbSNP
rs907694809 134 dbSNP
rs1334101130 138 dbSNP
rs1292118412 141 dbSNP
rs1395009962 143 dbSNP
rs922378544 145 dbSNP
rs1219065061 152 dbSNP
rs1385186996 153 dbSNP
rs752700596 155 dbSNP
rs1414655492 157 dbSNP
rs1245920592 162 dbSNP
rs1475690661 165 dbSNP
rs976534951 167 dbSNP
rs767156853 168 dbSNP
rs921653760 169 dbSNP
rs1379411548 171 dbSNP
rs1163986636 174 dbSNP
rs1366382435 174 dbSNP
rs1426791744 201 dbSNP
rs1017913021 202 dbSNP
rs1000373225 209 dbSNP
rs1432107936 213 dbSNP
rs1291188556 241 dbSNP
rs1362377132 242 dbSNP
rs1226967755 249 dbSNP
rs957816719 257 dbSNP
rs968972979 257 dbSNP
rs1020434962 258 dbSNP
rs1361074732 260 dbSNP
rs1226311922 263 dbSNP
rs1383372338 273 dbSNP
rs1032031196 274 dbSNP
rs978243398 282 dbSNP
rs144323205 284 dbSNP
rs1464410770 286 dbSNP
rs1010862843 287 dbSNP
rs1187932471 303 dbSNP
rs1385955432 311 dbSNP
rs966878634 313 dbSNP
rs34133786 314 dbSNP
rs1161746595 322 dbSNP
rs1413490253 326 dbSNP
rs528172523 327 dbSNP
rs1387043875 328 dbSNP
rs537224416 328 dbSNP
rs1435024280 331 dbSNP
rs1441960038 332 dbSNP
rs772042697 335 dbSNP
rs1384443063 356 dbSNP
rs559462615 359 dbSNP
rs545797985 362 dbSNP
rs1283284003 364 dbSNP
rs1033687103 368 dbSNP
rs1057454356 375 dbSNP
rs866938351 376 dbSNP
rs1001622351 380 dbSNP
rs1266010403 381 dbSNP
rs1285680008 385 dbSNP
rs905840632 388 dbSNP
rs1037719361 391 dbSNP
rs941239465 393 dbSNP
rs558947392 396 dbSNP
rs1237073477 400 dbSNP
rs1470654258 401 dbSNP
rs940066835 402 dbSNP
rs73780057 403 dbSNP
rs1052026368 420 dbSNP
rs1177833011 426 dbSNP
rs1403690417 428 dbSNP
rs1412215308 430 dbSNP
rs1046885049 433 dbSNP
rs929763977 435 dbSNP
rs1243402882 450 dbSNP
rs558476445 451 dbSNP
rs1349716649 453 dbSNP
rs1224013018 456 dbSNP
rs189292144 459 dbSNP
rs974456113 463 dbSNP
rs963775902 466 dbSNP
rs910872597 470 dbSNP
rs1278012897 477 dbSNP
rs1438557458 480 dbSNP
rs936313027 483 dbSNP
rs978423373 484 dbSNP
rs1250022408 487 dbSNP
rs765544302 489 dbSNP
rs1472494534 490 dbSNP
rs924936927 499 dbSNP
rs1379835940 503 dbSNP
rs977835235 511 dbSNP
rs1171422671 514 dbSNP
rs966431806 514 dbSNP
rs1431249841 516 dbSNP
rs1305840124 517 dbSNP
rs575468074 521 dbSNP
rs968996615 534 dbSNP
rs555520599 541 dbSNP
rs535627969 548 dbSNP
rs1329212952 559 dbSNP
rs1010498287 561 dbSNP
rs566642343 565 dbSNP
rs1274326459 585 dbSNP
rs73250092 588 dbSNP
rs1207529529 590 dbSNP
rs1035881313 595 dbSNP
rs1272689726 596 dbSNP
rs1034318780 609 dbSNP
rs1482868824 609 dbSNP
rs539825114 611 dbSNP
rs34928559 612 dbSNP
rs1223597112 613 dbSNP
rs1001592623 614 dbSNP
rs1431930877 617 dbSNP
rs1426389231 625 dbSNP
rs1373120986 626 dbSNP
rs1450847109 629 dbSNP
rs905969519 631 dbSNP
rs1037701507 636 dbSNP
rs1006260259 644 dbSNP
rs1389128705 647 dbSNP
rs995757337 654 dbSNP
rs1295015030 656 dbSNP
rs371602836 657 dbSNP
rs1386141427 665 dbSNP
rs1047380847 679 dbSNP
rs1373682032 680 dbSNP
rs1230646047 683 dbSNP
rs1367289109 683 dbSNP
rs1295497556 688 dbSNP
rs1341648181 690 dbSNP
rs1015599250 700 dbSNP
rs929925700 716 dbSNP
rs1267601644 719 dbSNP
rs922398062 720 dbSNP
rs1040883719 726 dbSNP
rs570752250 733 dbSNP
rs1051609041 735 dbSNP
rs1186050982 738 dbSNP
rs911011593 741 dbSNP
rs933128484 743 dbSNP
rs1444856423 749 dbSNP
rs900432656 758 dbSNP
rs776823254 761 dbSNP
rs936574773 765 dbSNP
rs1200557315 771 dbSNP
rs1158959986 775 dbSNP
rs1390655681 779 dbSNP
rs1420444101 785 dbSNP
rs550891137 786 dbSNP
rs1490956685 790 dbSNP
rs924990572 797 dbSNP
rs1396794745 800 dbSNP
rs548707713 808 dbSNP
rs74677776 810 dbSNP
rs568287988 816 dbSNP
rs960333810 821 dbSNP
rs1340685522 828 dbSNP
rs774146092 829 dbSNP
rs1331769180 835 dbSNP
rs917634302 838 dbSNP
rs1035848535 840 dbSNP
rs374666829 841 dbSNP
rs1253591144 843 dbSNP
rs761041087 848 dbSNP
rs760094536 849 dbSNP
rs139387818 852 dbSNP
rs1406523218 854 dbSNP
rs970121249 855 dbSNP
rs1329092220 857 dbSNP
rs1016322925 858 dbSNP
rs1410401502 859 dbSNP
rs1466572692 861 dbSNP
rs1006312547 865 dbSNP
rs1172900070 868 dbSNP
rs772262996 873 dbSNP
rs1464167851 878 dbSNP
rs1423152792 881 dbSNP
rs528260062 883 dbSNP
rs559407888 886 dbSNP
rs1352791232 887 dbSNP
rs1227066798 903 dbSNP
rs1015609284 905 dbSNP
rs369406364 911 dbSNP
rs184310929 919 dbSNP
rs532175245 925 dbSNP
rs1245278874 927 dbSNP
rs1253752428 928 dbSNP
rs1198614421 929 dbSNP
rs1196082779 948 dbSNP
rs994476974 952 dbSNP
rs1253664350 955 dbSNP
rs1471515436 955 dbSNP
rs749119917 971 dbSNP
rs563122745 973 dbSNP
rs1040855944 975 dbSNP
rs544918112 981 dbSNP
rs889626720 985 dbSNP
rs1042750599 986 dbSNP
rs1316814570 990 dbSNP
rs947176131 991 dbSNP
rs1263248720 998 dbSNP
rs1308912774 998 dbSNP
rs1372779715 999 dbSNP
rs796177686 1000 dbSNP
rs142841540 1001 dbSNP
rs988525482 1011 dbSNP
rs1221487489 1012 dbSNP
rs938914534 1013 dbSNP
rs1000773141 1014 dbSNP
rs1442737494 1019 dbSNP
rs903740248 1026 dbSNP
rs928904839 1029 dbSNP
rs150824975 1030 dbSNP
rs1204127857 1031 dbSNP
rs114674509 1035 dbSNP
rs1399587398 1036 dbSNP
rs1489408841 1050 dbSNP
rs1189439845 1051 dbSNP
rs1016457373 1054 dbSNP
rs985248774 1057 dbSNP
rs1432729341 1063 dbSNP
rs141412241 1067 dbSNP
rs1026713807 1072 dbSNP
rs1423396987 1082 dbSNP
rs1428092238 1083 dbSNP
rs997568073 1106 dbSNP
rs1307787898 1113 dbSNP
rs562625244 1114 dbSNP
rs1019458063 1115 dbSNP
rs1439217698 1119 dbSNP
rs1470740866 1123 dbSNP
rs1006766674 1132 dbSNP
rs1367534927 1134 dbSNP
rs1228406979 1137 dbSNP
rs889593816 1148 dbSNP
rs926816810 1154 dbSNP
rs1290286085 1156 dbSNP
rs371262460 1161 dbSNP
rs947112829 1173 dbSNP
rs962960520 1180 dbSNP
rs1245992839 1182 dbSNP
rs891568339 1189 dbSNP
rs1189247473 1190 dbSNP
rs1457736974 1192 dbSNP
rs1053189698 1194 dbSNP
rs982797031 1195 dbSNP
rs745951937 1196 dbSNP
rs938326202 1202 dbSNP
rs928286957 1209 dbSNP
rs573056270 1216 dbSNP
rs1029648468 1222 dbSNP
rs1349769877 1224 dbSNP
rs1440328496 1225 dbSNP
rs948960877 1231 dbSNP
rs1321943044 1238 dbSNP
rs997380960 1242 dbSNP
rs1224106491 1246 dbSNP
rs543675321 1250 dbSNP
rs964155044 1260 dbSNP
rs1226363656 1272 dbSNP
rs746242606 1276 dbSNP
rs1329753916 1279 dbSNP
rs1210562527 1282 dbSNP
rs1017865101 1283 dbSNP
rs1463645630 1288 dbSNP
rs1383456256 1294 dbSNP
rs1192581321 1297 dbSNP
rs1238201784 1299 dbSNP
rs1337454745 1301 dbSNP
rs139185721 1328 dbSNP
rs375634500 1331 dbSNP
rs1357612144 1332 dbSNP
rs1042312373 1340 dbSNP
rs1458198167 1348 dbSNP
rs1162076628 1358 dbSNP
rs1009418230 1360 dbSNP
rs1333817601 1361 dbSNP
rs1401527996 1364 dbSNP
rs1362806148 1366 dbSNP
rs1157239363 1367 dbSNP
rs1334246296 1368 dbSNP
rs1341846322 1370 dbSNP
rs1439564639 1371 dbSNP
rs1445427877 1376 dbSNP
rs896180209 1384 dbSNP
rs576128332 1385 dbSNP
rs1230140224 1386 dbSNP
rs1183061512 1393 dbSNP
rs937765151 1395 dbSNP
rs1471550080 1396 dbSNP
rs757728915 1398 dbSNP
rs1236407274 1399 dbSNP
rs926352063 1401 dbSNP
rs1038568302 1410 dbSNP
rs941481365 1412 dbSNP
rs1257250347 1423 dbSNP
rs1216012056 1429 dbSNP
rs908697529 1432 dbSNP
rs73780056 1440 dbSNP
rs934259627 1442 dbSNP
rs1470098048 1443 dbSNP
rs557047913 1446 dbSNP
rs115412564 1452 dbSNP
rs1017579515 1455 dbSNP
rs1006733831 1456 dbSNP
rs953992952 1459 dbSNP
rs1311954939 1462 dbSNP
rs1411360277 1463 dbSNP
rs772268225 1467 dbSNP
rs1349744321 1472 dbSNP
rs182585236 1474 dbSNP
rs149001858 1476 dbSNP
rs1020741397 1478 dbSNP
rs1217672837 1491 dbSNP
rs1279806688 1496 dbSNP
rs891629582 1503 dbSNP
rs777213271 1507 dbSNP
rs1296728009 1508 dbSNP
rs1002642941 1509 dbSNP
rs1419520136 1510 dbSNP
rs896368266 1512 dbSNP
rs368778333 1515 dbSNP
rs1366706892 1518 dbSNP
rs1476723422 1525 dbSNP
rs1172482326 1528 dbSNP
rs189376728 1529 dbSNP
rs1404126573 1530 dbSNP
rs1431277709 1532 dbSNP
rs1305929336 1533 dbSNP
rs147268946 1536 dbSNP
rs1485299271 1542 dbSNP
rs1001854959 1548 dbSNP
rs1329282314 1553 dbSNP
rs1434308358 1554 dbSNP
rs1186605879 1559 dbSNP
rs1478590381 1563 dbSNP
rs948930341 1576 dbSNP
rs142822253 1578 dbSNP
rs1049689030 1582 dbSNP
rs1272931883 1582 dbSNP
rs572303889 1583 dbSNP
rs1490466577 1587 dbSNP
rs1038155223 1594 dbSNP
rs929459067 1595 dbSNP
rs758806631 1596 dbSNP
rs552285290 1599 dbSNP
rs1219237019 1600 dbSNP
rs1450425407 1602 dbSNP
rs532087928 1603 dbSNP
rs887314981 1606 dbSNP
rs1289171609 1609 dbSNP
rs1166397986 1615 dbSNP
rs2974527 1620 dbSNP
rs1458167084 1623 dbSNP
rs934247149 1624 dbSNP
rs1388433131 1630 dbSNP
rs747968384 1637 dbSNP
rs966112916 1645 dbSNP
rs1399649588 1654 dbSNP
rs1366111562 1655 dbSNP
rs910540481 1656 dbSNP
rs538624689 1658 dbSNP
rs3805596 1661 dbSNP
rs370996880 1676 dbSNP
rs1434864290 1680 dbSNP
rs1245938109 1685 dbSNP
rs942743080 1691 dbSNP
rs1349867817 1694 dbSNP
rs1213664330 1696 dbSNP
rs925935223 1709 dbSNP
rs1465907580 1710 dbSNP
rs1466769692 1712 dbSNP
rs1186138137 1714 dbSNP
rs1011909937 1720 dbSNP
rs1424060084 1723 dbSNP
rs1189296143 1724 dbSNP
rs1366545614 1725 dbSNP
rs955875811 1731 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... PAR-CLIP data was present in GSM545217. RNA binding protein: AGO2. Condition:miR-7 transfection ...

- Hafner M; Landthaler M; Burger L; Khorshid et al., 2010, Cell.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agugguAACGAUUU----CACGUUAa 5'
                || | |||    ||||||| 
Target 5' ------UUUC-AAACCUUGUGCAAUu 3'
 		1 - 19
Article - Hafner M; Landthaler M; Burger L; Khorshid et al.
- Cell, 2010
RNA transcripts are subject to posttranscriptional gene regulation involving hundreds of RNA-binding proteins (RBPs) and microRNA-containing ribonucleoprotein complexes (miRNPs) expressed in a cell-type dependent fashion. We developed a cell-based crosslinking approach to determine at high resolution and transcriptome-wide the binding sites of cellular RBPs and miRNPs. The crosslinked sites are revealed by thymidine to cytidine transitions in the cDNAs prepared from immunopurified RNPs of 4-thiouridine-treated cells. We determined the binding sites and regulatory consequences for several intensely studied RBPs and miRNPs, including PUM2, QKI, IGF2BP1-3, AGO/EIF2C1-4 and TNRC6A-C. Our study revealed that these factors bind thousands of sites containing defined sequence motifs and have distinct preferences for exonic versus intronic or coding versus untranslated transcript regions. The precise mapping of binding sites across the transcriptome will be critical to the interpretation of the rapidly emerging data on genetic variation between individuals and how these variations contribute to complex genetic diseases.
LinkOut: [PMID: 20371350]
Experimental Support 2 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 55521.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' agugguAACGAUUU----CACGUUAa 5'
                || | |||    ||||||| 
Target 5' ------UUUC-AAACCUUGUGCAAUu 3'
 		1 - 19
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM545217
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / miR-7 transfection
Location of target site ENST00000282369.3 | 3UTR | UUUCAAACCUUGUGCAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 20371350 / GSE21578
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000282369.3 | 3UTR | UUUCAAACCUUGUGCAAUUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE42095 Differentiated embryonic stem cells 0.745 2.3e-5 0.818 9.3e-7 23 Click to see details
GSE28544 Breast cancer 0.597 1.0e-3 0.564 2.0e-3 24 Click to see details
GSE28260 Renal cortex and medulla -0.753 1.5e-3 -0.754 1.5e-3 13 Click to see details
GSE38974 Chronic obstructive pulmonary disease 0.292 7.8e-2 0.141 2.5e-1 25 Click to see details
GSE17306 Multiple myeloma -0.199 8.5e-2 0.317 1.3e-2 49 Click to see details
GSE38226 Liver fibrosis -0.239 1.5e-1 -0.384 4.3e-2 21 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.217 1.8e-1 -0.164 2.4e-1 20 Click to see details
GSE14794 Lymphoblastoid cells 0.094 1.9e-1 0.140 9.4e-2 90 Click to see details
GSE21687 Ependynoma primary tumors -0.109 2.0e-1 0.009 4.7e-1 64 Click to see details
GSE19350 CNS germ cell tumors 0.259 2.1e-1 0.350 1.3e-1 12 Click to see details
GSE15076 Monocyte-derived dendritic cells -0.447 2.3e-1 -0.300 3.1e-1 5 Click to see details
GSE17498 Multiple myeloma -0.097 2.8e-1 0.047 3.9e-1 40 Click to see details
GSE27834 Pluripotent stem cells -0.052 4.2e-1 -0.062 4.1e-1 16 Click to see details
GSE26953 Aortic valvular endothelial cells 0.012 4.8e-1 -0.045 4.2e-1 24 Click to see details
GSE32688 Pancreatic cancer 0.009 4.8e-1 -0.118 2.6e-1 32 Click to see details
GSE21849 B cell lymphoma 0.002 5.0e-1 0.079 3.4e-1 29 Click to see details
GSE21849 B cell lymphoma 0.002 5.0e-1 0.079 3.4e-1 29 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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