miRTarBase - #MIRT545360


—
pre-miRNA Information
pre-miRNA hsa-mir-4291   
Genomic Coordinates chr9: 93819357 - 93819421
Description Homo sapiens miR-4291 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4291
Sequence 11| UUCAGCAGGAACAGCU |26
Evidence Experimental
Experiments SOLiD
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1265713434 9 dbSNP
rs1433969451 12 dbSNP
rs1372852268 16 dbSNP
Putative Targets

miRNA Expression profile
Human miRNA Tissue Atlas
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LIN7C   
Synonyms LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3
Description lin-7 homolog C, crumbs cell polarity complex component
Transcript NM_018362   
Expression
Putative miRNA Targets on LIN7C
3'UTR of LIN7C
(miRNA target sites are highlighted)		 
>LIN7C|NM_018362|3'UTR
   1 TACATTTCAAAACTTGATATTTCATTTTGCGTTTTAGCTAGAGAAGTTTTCCTTGTGACTTACTAATGGCTGCAATGCCA
  81 ATGATTGTAAGAAAACAAACAAATTTATCATGAAATTCTCCTTGTCATTTTATAAATGCCTATTTTAACATCATTTATGG
 161 TTCCAGAGATGCATACACTTTTTTCTGACAAGAAAAAGTAAAAGGTGATGAGGGCAATTCTGTCCTACTGTTTTTACAGG
 241 CCTTTTTCAAATGCAGATTTTGTCATAAAGTTGTTATAGATTTTTTAAAATGCTTTTTTAATATTAAAATGTACTTTTAC
 321 ATTCTTAATCTTTTTTTAGAAAGGAAAAGTTTTCTTCATTTAGCTGCTGATTTAAAAGTAAAGTTCTCCAATTCTTTTTT
 401 TTTGCTTACTCTATTTTTTTTAACCTGTGAAATTTCTTTACAGTTTTCCAAGAAATTAAGCATAACAGTCTCATCTACGG
 481 CAGTTCATTACACTGTCAATGTTAACATCATTGCTGCATTTTGTACTTTGAACACACACATAATATATATAACCAGTGGT
 561 AAATCATGACTCAGTACAGTGCAAGTTTTTTCACTTTTACTTAAACATAATATATAATGGATATTCATTTATACTGATTT
 641 ATGAAAGTAAGTTTTTAAACACTGAAACAATCATTGCTAAAATACATATTCTTAATATTTGAGCATTGAGGCAAGAGGAT
 721 GTAATTGATAGCATTACTTATTACATCCCTATTTATGTTCAACCGTACATCAAATTATAAATGCAAAACAGGTTCAGATT
 801 TCATCTTTTGTGATTTCTTTTAAATACTATTCATTTTTATTTAAATGCACAGTATTTCCCCTATATTTTAGTCCTTCCAT
 881 TCCTAGAGACAAACCAGTTATTTGGTGGTGGGAAGTAGCTGAAGCAAAGAAGGAAAAGTAATACCTTTAACCTCACTAGC
 961 TTCAAGAGTAGACATTCTTACTAGCTCAATTTAAATAATTGATTTTAAATAGGAAGAAAAGAGGATATATTTAAGATACA
1041 TAGAAATTATGATGTGAAGTATTCATGAGAATCTGTAGATTCCATCAAAATAAGTAGGAACTCATACTAAAATTGTTGGA
1121 TTTAAAGAGGCAACTTTTGTTTATGATTCAAATATGGGAATTTGAGAAATATTTCATTTGTCCACTGGATGTCACTATTT
1201 TACTAAAAGGCAGCTATTAGTGTGGGACTGTGACTGAGGTCTTAAAGACTGAAAGAGTTGGGGTTCATTTTCTGTTACAA
1281 CTTACAGGAACATTTGTACTTTAAGAAAAATTTAAGTGACAAATGTTAGAAGATGATGGATTGAAAAATATAAGTAATTT
1361 GGCATATTGACCCTATATAAAAAAGTGGGCATTTTGTAACATTCCTTCAGGAAGAATAGAATTGTATGCTTTTTTCTGCA
1441 TGTTTGTGATCACTGTGAGTCTCAGATGATTATTCCAGTTTTCAATGATTTTTCAAAATAAAAGTCAATCAGCATTGTTA
1521 TTTATCATTAAGGTATTGAACACTGGATTGCATGGTTGAATGTGTCTTTAATCCACTACAAAATGTGCTTGTTATTGATA
1601 GGATCATGTTGTTAAATTGTAAATTTTCAAAATTAATTGATGTTTTAAAAATGTTGAGACCAAAGTAGTATAGAAGTATG
1681 GACTTAATTTAATTGTAAAATTATTAGAGGTATTTGTTGTAGAGCTTTATATATTAAAGAGAGGTATTGGTGCATATAAA
1761 AACAGTAATATTATTGTTATGCTTGTATTCTTGCATTTCAGGGTAAGTAAACCCTGAAGAAATCTTATTTTAGTATAGCT
1841 ACAGCTGCAGTAGCTTTTAAGTATGTATCAACATTTCATTATAAATTATAGCTTCCTGGTTCTGTGTCTCAGCTGTTTCA
1921 GAACTTTCAGCCAAGTTAAATCTTTTTTGGTGTTGAAACTTTTAGTAAGTTGAGTAAGCTATTTTTTTCCCTACGGTAAT
2001 CCACAATCTGTTCTTTGTGTGGGTTGACACCTATTTATAATTCTTAAAATAAGGGTAGCTCAAAGGAGCCAAGTACAGTA
2081 GTTTAGCTTGCTACTGTTGAGCATGAATAGCAGTAGGTTGTTTTCATTAATGCAGTTTTCATAATGTATCCCAGAATTTT
2161 AAATCTTGACCATAGAAAAATACAGTCATTCATTGGCAAAGATGTACAGTGGTGGTTTAGTGCAGTGAGGAAATGATGGG
2241 AATTTTTATCTTAGAAATGGATGATTCGTGAATAAAACTAGGTACATAGTAAGTGTATGATAGATGTTTGATTTGTAAAT
2321 TACAAATATAAATTATCACCCCCATTTCCATTTATTTTCTTGATATATCAAAATGTGTTGACTTAGTGATTCTCAATCTT
2401 AGCTACATATTAGCCTGGCAGAGCTTTAAAAAATTGATACCTGGGTCCTATTCCATAACAACTAAATCAAAATCACCCTT
2481 TTTTTTTTTTTTGTAAAGCTTTCCAGGTGGTTCTAAAGGACACCTAGGGTCAATAACCCATTATAAAATGATCTGATTAC
2561 ACTGGACACTCTTAGGAAGTATCAAAATAGAACAGTTCAATTTGCAGCTACTTAATGATTAATTACATTTCTTAGGTTTT
2641 TTTTTTGTTTTTTTTTTGGTTTGTTTGTTTTTTGTTTTAAAAGAGACAGGATCTTGCTTTGTCTCCCAGGCTGGAACACA
2721 GTGGTGTGATCATAGCTCACTGCAGCCTGAAACTCCTTGGCTTCCACCTCAGCCTCCCAAAGCATTAGGATTATAGGCGT
2801 GAGCCACTGCACCTGGCCAAGTAATTTCTTTTAGGAATAAAAGGTACTTGGCATTCCTTATTTGGGAAGTAATTACAGTC
2881 TTATCTTTTTTTTTCTTTTTTCTTTTTTTTAATAAAATCTACCAGTAATTTAAATGTGAGCTTTTTATGTCTGTCATCAT
2961 TCTGCCCCCTTTGCCTTTAAAACTTACAAAAATACGTGTTTGTTATTTGAGAAAGCATGTTTAAAAATTGCAGATGAGAA
3041 ATATTGTCGTTAATAATTATGTACTGTCTTAATGTGGGCACTTCATTTGTTAGTATAATACTAGATAATAGCAGCCTAGT
3121 TCTTTAGGATTTGACGATTCAAATTTTTTTTTTGTTTTTTGTTTTTGTTTTTTTTTGAGACAGAGTCTTGCTCTGTTGCC
3201 CAGGCTGGCGTGCAGTGGTGTGATCTCGGCTCACTTCAGCCTCCGCCACCTCAAGGCAGTTCAAGCAATTCTCCTGCCTC
3281 AGCCTCCCGAGTAGCTAGGACTACAGGCGTGTGCCACCTCTCCCGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGTT
3361 TCACCGTGTTAGCCAGGATGATCTCGATCTCCTGACCTCGTGATTCGCCCGCCTCGGCCTCCCAAAGTGCTGGAATTACT
3441 GGCGTGAGCCACCATGCCCAGCCTCAAATATGTTTTTAAAAAATATCATTGTCCTCCTCCTCTTAAGATTTTTTTAAGTT
3521 ATTTTGCTCAAGTACTTAAGTAGTCTGGCTCAAGTACTTTGTTTACAATTAAAATGGATATTATAGCATTTAATAGAAGA
3601 AATGGTTATGGCTTATCCAAAAAGAATGTCAGCATGACCTGGTGTAGACTTAAAAAACTACATGTTTGTGAATATTTTAT
3681 AATGTGGAATGATCATTGAAATATCAAGGATTCTAGTAATTGTATTTCCTGAATAAATGTATGTTTATGAATTTTCTAAC
3761 TTACATTTTGTTGTGTCCTCTGCCAACAATCTGGTTTTATAATTGTTGTCTAAAGTTTGCTAGTAGTGTTTCTTCAAAGG
3841 TTATTCCAGGTATGGTTAAGTAGTGAGAAAAATCACTTATTAATTTTCAAGAACTTTGAGACTAATTTGTATTGACTCGG
3921 TTTTTTAAAATAACTGGCAAATGCTATGCTTCTACTTTTAAAATTTGTGGTAATACCCAGAATGGATGTAAAATAACATT
4001 TTTCAATAGATTACTTCATTTATCAATTTAATTCTGATTTTAAGGCTTATTTAAAATAAATTTGTATGAGTTATGTCCTC
4081 GTTCTTTGGATTTGAAAAAAGTTGATATAACTACACAATAGATAACGTTTATGAAAGGTATGTATAAAAAAACATAATTC
4161 CTGGTGGCTGCTGAAATGAAACTTTGAATTTCTATATTTTGCTTTGTCTTTCATAAAATTTAAAGAAAACAAAAAAAAAA
4241 AAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' ucGA-CAAGGACGACUu 5'
            || ||  ||||||| 
Target 5' tcCTGGTGGCTGCTGAa 3'
 4159 - 4175 146.00 -13.50
2 
miRNA  3' ucgACAAGGACGACUu 5'
             | |  ||||||| 
Target 5' tcaTTTAGCTGCTGAt 3'
 356 - 371 141.00 -9.80
3 
miRNA  3' ucGACAAGGACGACUu 5'
            :|| | |||:||| 
Target 5' gcTTGCTACTGTTGAg 3'
 2086 - 2101 134.00 -9.90
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN26982498 3 COSMIC
COSN32053326 24 COSMIC
COSN21328748 41 COSMIC
COSN30463295 43 COSMIC
COSN31509685 51 COSMIC
COSN30156385 66 COSMIC
COSN26982497 80 COSMIC
COSN22280575 81 COSMIC
COSN22819511 122 COSMIC
COSN31558410 146 COSMIC
COSN18735872 148 COSMIC
COSN7000670 293 COSMIC
COSN16904266 671 COSMIC
COSN16582571 863 COSMIC
COSN8440978 967 COSMIC
COSN21695459 1021 COSMIC
COSN17861710 1116 COSMIC
COSN32131584 1226 COSMIC
COSN23253799 1378 COSMIC
COSN31609877 1604 COSMIC
COSN4721226 1632 COSMIC
COSN31588817 1645 COSMIC
COSN30166367 1649 COSMIC
COSN24303837 1657 COSMIC
COSN21487515 1658 COSMIC
COSN32131583 1972 COSMIC
COSN32131582 2201 COSMIC
COSN7000669 2575 COSMIC
COSN20108093 2636 COSMIC
COSN28201476 2648 COSMIC
COSN22819173 2885 COSMIC
COSN10084185 3026 COSMIC
COSN1527232 3309 COSMIC
COSN16585146 3495 COSMIC
COSN2474156 3507 COSMIC
COSN24367242 3525 COSMIC
COSN32057163 3545 COSMIC
COSN31535379 3602 COSMIC
COSN23048056 3677 COSMIC
COSN7000668 3698 COSMIC
COSN5905889 3901 COSMIC
COSN16785339 3920 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs756712341 4 dbSNP
rs372064844 5 dbSNP
rs1242966335 6 dbSNP
rs767147469 10 dbSNP
rs767266289 14 dbSNP
rs1233132837 20 dbSNP
rs751237307 24 dbSNP
rs766164091 30 dbSNP
rs773079709 31 dbSNP
rs765117073 41 dbSNP
rs757642356 46 dbSNP
rs761747119 46 dbSNP
rs775493922 51 dbSNP
rs1173593228 52 dbSNP
rs1393752929 60 dbSNP
rs1159595776 65 dbSNP
rs1421955467 65 dbSNP
rs988400909 66 dbSNP
rs1041669607 68 dbSNP
rs1367700943 76 dbSNP
rs961017522 79 dbSNP
rs1010658330 80 dbSNP
rs927967390 81 dbSNP
rs981155034 86 dbSNP
rs969455093 91 dbSNP
rs937475067 97 dbSNP
rs1316618629 104 dbSNP
rs745920873 104 dbSNP
rs1466536573 113 dbSNP
rs1468980136 115 dbSNP
rs1266565474 118 dbSNP
rs1208677514 120 dbSNP
rs528221000 125 dbSNP
rs1276734574 134 dbSNP
rs1231138658 139 dbSNP
rs1407732496 142 dbSNP
rs1330803851 147 dbSNP
rs1005383091 149 dbSNP
rs950256033 151 dbSNP
rs563732183 153 dbSNP
rs1460511850 154 dbSNP
rs1026012034 157 dbSNP
rs1379116455 176 dbSNP
rs1447413407 177 dbSNP
rs998094689 178 dbSNP
rs372690110 180 dbSNP
rs1278828737 185 dbSNP
rs901064109 187 dbSNP
rs1229767140 189 dbSNP
rs369672861 190 dbSNP
rs1335702230 192 dbSNP
rs1213209677 194 dbSNP
rs1271346678 195 dbSNP
rs1006525863 205 dbSNP
rs1205849411 207 dbSNP
rs1232758646 222 dbSNP
rs1468953103 227 dbSNP
rs904275463 233 dbSNP
rs1183930631 235 dbSNP
rs1456678494 236 dbSNP
rs1402797639 254 dbSNP
rs574896999 277 dbSNP
rs1042824682 287 dbSNP
rs1476754277 290 dbSNP
rs1465649128 292 dbSNP
rs1328140289 299 dbSNP
rs1352663403 305 dbSNP
rs1376512345 306 dbSNP
rs1450016294 309 dbSNP
rs946900323 310 dbSNP
rs556949554 311 dbSNP
rs1053138974 314 dbSNP
rs1188822823 316 dbSNP
rs542123619 320 dbSNP
rs574524713 321 dbSNP
rs939636882 325 dbSNP
rs1450895660 328 dbSNP
rs1246610638 329 dbSNP
rs759313343 339 dbSNP
rs553177965 342 dbSNP
rs1436553878 343 dbSNP
rs1212749671 349 dbSNP
rs1208469385 352 dbSNP
rs953157360 353 dbSNP
rs1281338935 358 dbSNP
rs1185358050 363 dbSNP
rs1425281900 365 dbSNP
rs1475481044 367 dbSNP
rs948055997 369 dbSNP
rs1417367752 377 dbSNP
rs1344414169 378 dbSNP
rs1251912339 380 dbSNP
rs528842301 385 dbSNP
rs1374640364 394 dbSNP
rs377130067 403 dbSNP
rs1028761873 404 dbSNP
rs1295194350 405 dbSNP
rs534277723 408 dbSNP
rs1341063175 409 dbSNP
rs965898060 410 dbSNP
rs1336100282 411 dbSNP
rs1020621196 422 dbSNP
rs1338086786 422 dbSNP
rs1221436299 431 dbSNP
rs1010191298 442 dbSNP
rs1033041797 444 dbSNP
rs566929988 448 dbSNP
rs1264948988 460 dbSNP
rs1025494910 465 dbSNP
rs1191935136 468 dbSNP
rs976964056 470 dbSNP
rs117196481 478 dbSNP
rs145145795 479 dbSNP
rs1045899299 487 dbSNP
rs140815042 492 dbSNP
rs897368479 519 dbSNP
rs1160212309 523 dbSNP
rs1037682997 529 dbSNP
rs765150551 534 dbSNP
rs941651890 538 dbSNP
rs908853788 539 dbSNP
rs372010878 540 dbSNP
rs1186075998 541 dbSNP
rs1438637792 542 dbSNP
rs1442309045 546 dbSNP
rs1304865801 547 dbSNP
rs1370884006 550 dbSNP
rs984494122 551 dbSNP
rs1288600900 557 dbSNP
rs1351769380 566 dbSNP
rs1204199832 574 dbSNP
rs1281639417 585 dbSNP
rs1452863770 591 dbSNP
rs1207356094 592 dbSNP
rs550973691 603 dbSNP
rs1340376971 604 dbSNP
rs1452483507 607 dbSNP
rs1274188133 609 dbSNP
rs1364162968 610 dbSNP
rs1021411193 616 dbSNP
rs1452706117 617 dbSNP
rs1229039528 618 dbSNP
rs1009969813 619 dbSNP
rs891514735 622 dbSNP
rs1463127083 627 dbSNP
rs1340797214 634 dbSNP
rs1285687295 639 dbSNP
rs921691314 640 dbSNP
rs1445779309 646 dbSNP
rs1439349550 647 dbSNP
rs1309716889 654 dbSNP
rs975847710 656 dbSNP
rs1238732935 657 dbSNP
rs1339775583 657 dbSNP
rs761865560 680 dbSNP
rs1020148817 685 dbSNP
rs1308167707 686 dbSNP
rs1411117439 693 dbSNP
rs1271982799 694 dbSNP
rs1466696499 700 dbSNP
rs776738239 706 dbSNP
rs939477908 715 dbSNP
rs906825823 721 dbSNP
rs1418313201 727 dbSNP
rs529622350 731 dbSNP
rs568559231 733 dbSNP
rs550033331 736 dbSNP
rs559334788 737 dbSNP
rs905907364 738 dbSNP
rs1459896959 746 dbSNP
rs930075526 755 dbSNP
rs1253151992 757 dbSNP
rs190835624 759 dbSNP
rs775671159 764 dbSNP
rs976615138 765 dbSNP
rs1014383289 772 dbSNP
rs186386542 777 dbSNP
rs1327252598 781 dbSNP
rs965584387 790 dbSNP
rs1251102755 791 dbSNP
rs76926886 792 dbSNP
rs1292227100 808 dbSNP
rs985359213 817 dbSNP
rs1453506636 827 dbSNP
rs1363275512 828 dbSNP
rs1291814990 829 dbSNP
rs1219887489 847 dbSNP
rs1226383866 861 dbSNP
rs182115552 863 dbSNP
rs968395365 879 dbSNP
rs1193929992 889 dbSNP
rs1334146698 895 dbSNP
rs1258020577 900 dbSNP
rs1485844229 909 dbSNP
rs1288911789 914 dbSNP
rs1230088723 923 dbSNP
rs564368068 937 dbSNP
rs941586676 940 dbSNP
rs1374207301 944 dbSNP
rs1461913901 945 dbSNP
rs1297065457 956 dbSNP
rs534351434 959 dbSNP
rs1049173450 965 dbSNP
rs931649989 966 dbSNP
rs921640160 973 dbSNP
rs975795061 984 dbSNP
rs944487391 985 dbSNP
rs1295672585 987 dbSNP
rs1306348076 999 dbSNP
rs1322053661 1007 dbSNP
rs117508943 1015 dbSNP
rs988679445 1016 dbSNP
rs1348365429 1024 dbSNP
rs541754444 1024 dbSNP
rs1209851036 1030 dbSNP
rs1035847637 1036 dbSNP
rs574715204 1039 dbSNP
rs1188425323 1048 dbSNP
rs980055331 1052 dbSNP
rs970039363 1054 dbSNP
rs1191689931 1068 dbSNP
rs1397379851 1082 dbSNP
rs1435769799 1093 dbSNP
rs1173395077 1103 dbSNP
rs1471870515 1108 dbSNP
rs1024341783 1112 dbSNP
rs774907772 1114 dbSNP
rs1191816663 1116 dbSNP
rs1379989409 1133 dbSNP
rs1305588536 1134 dbSNP
rs1371613039 1151 dbSNP
rs1045313760 1155 dbSNP
rs1277919310 1164 dbSNP
rs1012471569 1171 dbSNP
rs572245414 1173 dbSNP
rs1479158944 1184 dbSNP
rs1261480021 1188 dbSNP
rs888671381 1197 dbSNP
rs1186713824 1209 dbSNP
rs1255493666 1211 dbSNP
rs1245193916 1216 dbSNP
rs1193488186 1220 dbSNP
rs1014331133 1226 dbSNP
rs1048391451 1235 dbSNP
rs929926907 1243 dbSNP
rs918717619 1258 dbSNP
rs1451058597 1265 dbSNP
rs559396871 1269 dbSNP
rs7934816 1276 dbSNP
rs1440085463 1281 dbSNP
rs911037036 1285 dbSNP
rs985265749 1286 dbSNP
rs1224089377 1287 dbSNP
rs1005729063 1288 dbSNP
rs968634669 1289 dbSNP
rs914456478 1291 dbSNP
rs577131427 1294 dbSNP
rs1268470914 1297 dbSNP
rs955892689 1305 dbSNP
rs558246078 1310 dbSNP
rs1245447127 1311 dbSNP
rs1481848676 1313 dbSNP
rs1178119434 1341 dbSNP
rs1003019134 1350 dbSNP
rs1049961982 1351 dbSNP
rs969810249 1354 dbSNP
rs1166566345 1358 dbSNP
rs1023771762 1363 dbSNP
rs1040038809 1364 dbSNP
rs1012336136 1375 dbSNP
rs888702642 1377 dbSNP
rs912993905 1379 dbSNP
rs1369368213 1391 dbSNP
rs1272721985 1392 dbSNP
rs1048624734 1404 dbSNP
rs935846861 1413 dbSNP
rs1226814432 1416 dbSNP
rs994214628 1419 dbSNP
rs1295303562 1421 dbSNP
rs1335586615 1424 dbSNP
rs897134551 1440 dbSNP
rs1041156254 1445 dbSNP
rs944136493 1455 dbSNP
rs925813688 1457 dbSNP
rs980003389 1472 dbSNP
rs969988435 1475 dbSNP
rs1257726756 1479 dbSNP
rs1474615349 1483 dbSNP
rs1160926431 1485 dbSNP
rs780892183 1488 dbSNP
rs1410471559 1497 dbSNP
rs1169588904 1498 dbSNP
rs1388523532 1500 dbSNP
rs1176960483 1503 dbSNP
rs917232125 1503 dbSNP
rs1434981949 1504 dbSNP
rs1315059110 1508 dbSNP
rs539971716 1508 dbSNP
rs575525681 1513 dbSNP
rs763345002 1514 dbSNP
rs1282498365 1530 dbSNP
rs1341477129 1534 dbSNP
rs557374404 1538 dbSNP
rs1049595174 1540 dbSNP
rs144070309 1543 dbSNP
rs947202999 1544 dbSNP
rs1272861979 1551 dbSNP
rs140284809 1553 dbSNP
rs1248452357 1566 dbSNP
rs1213423478 1567 dbSNP
rs568699977 1573 dbSNP
rs955759268 1579 dbSNP
rs189789937 1580 dbSNP
rs1243362618 1584 dbSNP
rs534862016 1584 dbSNP
rs981102993 1585 dbSNP
rs970221103 1591 dbSNP
rs570727480 1593 dbSNP
rs771140175 1601 dbSNP
rs1185895971 1603 dbSNP
rs1388217970 1614 dbSNP
rs1436409709 1617 dbSNP
rs1174016297 1623 dbSNP
rs1376367815 1630 dbSNP
rs1434345608 1634 dbSNP
rs1328298736 1639 dbSNP
rs1332369385 1639 dbSNP
rs1210647851 1645 dbSNP
rs1431521163 1648 dbSNP
rs1006087540 1653 dbSNP
rs1363610534 1654 dbSNP
rs1237030805 1661 dbSNP
rs551841533 1666 dbSNP
rs1347540467 1668 dbSNP
rs1198396107 1671 dbSNP
rs1275836078 1678 dbSNP
rs1012407835 1683 dbSNP
rs1365437743 1687 dbSNP
rs754626924 1694 dbSNP
rs1455531086 1695 dbSNP
rs1194112463 1701 dbSNP
rs376567389 1703 dbSNP
rs1394263418 1710 dbSNP
rs773410777 1729 dbSNP
rs751268758 1731 dbSNP
rs530564342 1739 dbSNP
rs994808476 1744 dbSNP
rs997035023 1744 dbSNP
rs1387374979 1747 dbSNP
rs563127015 1747 dbSNP
rs897378891 1753 dbSNP
rs1020044352 1755 dbSNP
rs1170575290 1766 dbSNP
rs1319951310 1768 dbSNP
rs901450744 1770 dbSNP
rs1443752383 1773 dbSNP
rs1304750376 1776 dbSNP
rs1008192941 1781 dbSNP
rs1370763335 1782 dbSNP
rs1231491699 1785 dbSNP
rs889875661 1787 dbSNP
rs548127712 1795 dbSNP
rs541858956 1796 dbSNP
rs766020751 1799 dbSNP
rs1467982417 1802 dbSNP
rs1265704695 1803 dbSNP
rs1008570841 1804 dbSNP
rs891495170 1813 dbSNP
rs892958728 1819 dbSNP
rs1052935891 1821 dbSNP
rs186154274 1833 dbSNP
rs1449694293 1847 dbSNP
rs374236602 1849 dbSNP
rs559567747 1858 dbSNP
rs541350617 1864 dbSNP
rs925759628 1866 dbSNP
rs928536795 1871 dbSNP
rs1044271044 1875 dbSNP
rs1409883233 1882 dbSNP
rs1170328285 1888 dbSNP
rs758207279 1891 dbSNP
rs917180640 1895 dbSNP
rs993200889 1896 dbSNP
rs948388877 1910 dbSNP
rs577095516 1912 dbSNP
rs1331285151 1921 dbSNP
rs1336657881 1927 dbSNP
rs1408854482 1936 dbSNP
rs565101799 1937 dbSNP
rs984491399 1947 dbSNP
rs1484172740 1950 dbSNP
rs1233330664 1962 dbSNP
rs1235287613 1963 dbSNP
rs1354147894 1965 dbSNP
rs1209504767 1966 dbSNP
rs1250975375 1970 dbSNP
rs984207246 1971 dbSNP
rs952904802 1981 dbSNP
rs1249857154 1989 dbSNP
rs1476258334 1993 dbSNP
rs952930251 1994 dbSNP
rs1027585501 1995 dbSNP
rs574745390 1997 dbSNP
rs1225652258 2005 dbSNP
rs765195911 2006 dbSNP
rs1397686215 2016 dbSNP
rs965566358 2017 dbSNP
rs1307304297 2024 dbSNP
rs1305838846 2028 dbSNP
rs961938027 2031 dbSNP
rs1019823230 2032 dbSNP
rs891447298 2041 dbSNP
rs1031776903 2046 dbSNP
rs1312413656 2053 dbSNP
rs1410511129 2056 dbSNP
rs1338553878 2059 dbSNP
rs546319137 2063 dbSNP
rs555388257 2063 dbSNP
rs16917051 2073 dbSNP
rs1028435771 2082 dbSNP
rs948536066 2090 dbSNP
rs1166963880 2097 dbSNP
rs1255577324 2108 dbSNP
rs1422084302 2113 dbSNP
rs557186409 2119 dbSNP
rs895688776 2139 dbSNP
rs535798107 2141 dbSNP
rs1429569139 2147 dbSNP
rs1167086621 2161 dbSNP
rs1376964674 2168 dbSNP
rs1434949257 2172 dbSNP
rs1372322480 2174 dbSNP
rs574762993 2178 dbSNP
rs553217201 2180 dbSNP
rs1165181086 2183 dbSNP
rs939964072 2185 dbSNP
rs908523252 2191 dbSNP
rs1296272717 2192 dbSNP
rs1364361169 2196 dbSNP
rs1053372628 2198 dbSNP
rs934473877 2204 dbSNP
rs984548741 2209 dbSNP
rs931370143 2218 dbSNP
rs1186689387 2221 dbSNP
rs1483102202 2228 dbSNP
rs1255589007 2230 dbSNP
rs907155719 2239 dbSNP
rs1482339680 2248 dbSNP
rs142156182 2260 dbSNP
rs948416400 2264 dbSNP
rs118079541 2267 dbSNP
rs965510024 2268 dbSNP
rs1019769778 2270 dbSNP
rs1454940896 2277 dbSNP
rs1174966510 2280 dbSNP
rs1357053913 2284 dbSNP
rs181308599 2286 dbSNP
rs1266451668 2291 dbSNP
rs1247422472 2294 dbSNP
rs1387193309 2311 dbSNP
rs148657140 2320 dbSNP
rs760831768 2323 dbSNP
rs1327782324 2335 dbSNP
rs930409027 2337 dbSNP
rs75592971 2349 dbSNP
rs1000276094 2359 dbSNP
rs1229490637 2366 dbSNP
rs1310651666 2374 dbSNP
rs1241358762 2377 dbSNP
rs1268850494 2384 dbSNP
rs1207412689 2386 dbSNP
rs1255397551 2389 dbSNP
rs558033517 2394 dbSNP
rs973313032 2396 dbSNP
rs1012708561 2402 dbSNP
rs895641322 2414 dbSNP
rs569324382 2419 dbSNP
rs1391699133 2423 dbSNP
rs1167069016 2433 dbSNP
rs548002260 2434 dbSNP
rs1020315279 2441 dbSNP
rs1291566206 2452 dbSNP
rs987033321 2466 dbSNP
rs954255002 2468 dbSNP
rs372867876 2475 dbSNP
rs1391936591 2478 dbSNP
rs1028341116 2479 dbSNP
rs1275666887 2479 dbSNP
rs1472852823 2490 dbSNP
rs1413580290 2491 dbSNP
rs1011551598 2492 dbSNP
rs111506157 2493 dbSNP
rs1166447184 2493 dbSNP
rs1182491599 2493 dbSNP
rs1245357704 2493 dbSNP
rs1481795446 2493 dbSNP
rs189568285 2493 dbSNP
rs770889847 2494 dbSNP
rs1162525069 2495 dbSNP
rs1462267779 2495 dbSNP
rs1308905068 2497 dbSNP
rs1350091200 2500 dbSNP
rs1408153207 2503 dbSNP
rs898188366 2508 dbSNP
rs921304318 2509 dbSNP
rs1379912490 2515 dbSNP
rs529655544 2522 dbSNP
rs6484306 2526 dbSNP
rs1487717595 2527 dbSNP
rs868625381 2529 dbSNP
rs1189535043 2533 dbSNP
rs912706377 2535 dbSNP
rs1472149737 2537 dbSNP
rs988726589 2548 dbSNP
rs1421530539 2555 dbSNP
rs1209939756 2556 dbSNP
rs772250646 2558 dbSNP
rs1167724604 2562 dbSNP
rs1368399825 2568 dbSNP
rs999129561 2569 dbSNP
rs907020666 2571 dbSNP
rs746232021 2573 dbSNP
rs1359851458 2585 dbSNP
rs1447351489 2588 dbSNP
rs1282996896 2590 dbSNP
rs1364679600 2598 dbSNP
rs547691270 2599 dbSNP
rs1229689211 2600 dbSNP
rs1297321421 2605 dbSNP
rs1012801949 2610 dbSNP
rs1286586665 2625 dbSNP
rs894367814 2636 dbSNP
rs1207384305 2637 dbSNP
rs532494428 2637 dbSNP
rs1331969846 2638 dbSNP
rs1303689603 2645 dbSNP
rs1385252647 2646 dbSNP
rs11378974 2647 dbSNP
rs1450010573 2647 dbSNP
rs181959099 2647 dbSNP
rs930271795 2648 dbSNP
rs919039094 2649 dbSNP
rs1332266232 2652 dbSNP
rs1320407255 2658 dbSNP
rs200444857 2658 dbSNP
rs968362866 2659 dbSNP
rs768721980 2662 dbSNP
rs1324934400 2663 dbSNP
rs1457747046 2664 dbSNP
rs1217049612 2666 dbSNP
rs1390724446 2667 dbSNP
rs1208069311 2668 dbSNP
rs374646168 2670 dbSNP
rs1156372126 2671 dbSNP
rs1452433441 2674 dbSNP
rs1377641008 2679 dbSNP
rs1022668931 2685 dbSNP
rs1200578343 2688 dbSNP
rs1452142196 2690 dbSNP
rs1414302235 2691 dbSNP
rs1036100519 2693 dbSNP
rs1457798934 2699 dbSNP
rs940208292 2701 dbSNP
rs1012654358 2703 dbSNP
rs568968263 2705 dbSNP
rs912749067 2716 dbSNP
rs1324624408 2724 dbSNP
rs1330828506 2726 dbSNP
rs986938928 2727 dbSNP
rs954287879 2733 dbSNP
rs565066427 2748 dbSNP
rs1466686282 2752 dbSNP
rs543603387 2761 dbSNP
rs990190927 2766 dbSNP
rs1204995316 2771 dbSNP
rs1345829438 2783 dbSNP
rs1140711 2787 dbSNP
rs189791077 2790 dbSNP
rs771534636 2793 dbSNP
rs749833234 2795 dbSNP
rs995417387 2796 dbSNP
rs186886553 2798 dbSNP
rs1024102698 2799 dbSNP
rs1472987149 2807 dbSNP
rs1181532634 2809 dbSNP
rs944095978 2810 dbSNP
rs1012670349 2815 dbSNP
rs912645357 2818 dbSNP
rs894398979 2820 dbSNP
rs935493419 2837 dbSNP
rs1381488601 2838 dbSNP
rs925505470 2838 dbSNP
rs1408763180 2842 dbSNP
rs574761408 2854 dbSNP
rs368281088 2855 dbSNP
rs1402432960 2856 dbSNP
rs1048963797 2860 dbSNP
rs374380557 2865 dbSNP
rs1354042646 2866 dbSNP
rs1197311214 2871 dbSNP
rs897472208 2877 dbSNP
rs1277105253 2883 dbSNP
rs1393969083 2885 dbSNP
rs1204632302 2888 dbSNP
rs1249745625 2890 dbSNP
rs1425591682 2894 dbSNP
rs1188900812 2895 dbSNP
rs1472050123 2895 dbSNP
rs979669997 2895 dbSNP
rs1170877166 2901 dbSNP
rs1169705778 2902 dbSNP
rs1371490853 2902 dbSNP
rs1036416076 2908 dbSNP
rs1305741648 2909 dbSNP
rs1396072275 2909 dbSNP
rs969654681 2909 dbSNP
rs915558755 2910 dbSNP
rs1230419748 2911 dbSNP
rs1338613682 2911 dbSNP
rs370418722 2918 dbSNP
rs1298064944 2922 dbSNP
rs991167760 2938 dbSNP
rs959783982 2948 dbSNP
rs1484308082 2950 dbSNP
rs1035851069 2970 dbSNP
rs1256154329 2973 dbSNP
rs944485128 2984 dbSNP
rs1190994058 2987 dbSNP
rs1443388880 2987 dbSNP
rs911597329 2995 dbSNP
rs1051270659 2996 dbSNP
rs1209017660 3000 dbSNP
rs1004005594 3005 dbSNP
rs1347160112 3009 dbSNP
rs951282152 3024 dbSNP
rs932805560 3027 dbSNP
rs754778247 3028 dbSNP
rs1275440513 3029 dbSNP
rs754539144 3044 dbSNP
rs1437219440 3048 dbSNP
rs376095273 3049 dbSNP
rs1225873647 3066 dbSNP
rs990389039 3078 dbSNP
rs957623865 3079 dbSNP
rs1314163649 3092 dbSNP
rs1039644504 3093 dbSNP
rs1255505992 3100 dbSNP
rs1008183995 3107 dbSNP
rs924652444 3118 dbSNP
rs1211156727 3122 dbSNP
rs535127879 3125 dbSNP
rs1464765540 3132 dbSNP
rs971511666 3135 dbSNP
rs1024303849 3136 dbSNP
rs541315096 3142 dbSNP
rs935455213 3143 dbSNP
rs1308093327 3146 dbSNP
rs991320624 3147 dbSNP
rs958523687 3152 dbSNP
rs79729432 3153 dbSNP
rs1159883260 3154 dbSNP
rs1458332474 3154 dbSNP
rs1387805670 3155 dbSNP
rs1295078618 3161 dbSNP
rs1432721937 3161 dbSNP
rs1367976050 3167 dbSNP
rs1027553201 3168 dbSNP
rs1300797571 3169 dbSNP
rs1343759635 3173 dbSNP
rs1269383034 3177 dbSNP
rs1431151532 3177 dbSNP
rs904004375 3182 dbSNP
rs1167870965 3185 dbSNP
rs758032631 3187 dbSNP
rs948259023 3191 dbSNP
rs897707756 3194 dbSNP
rs1014600170 3201 dbSNP
rs1264799433 3203 dbSNP
rs1485460583 3204 dbSNP
rs991115473 3209 dbSNP
rs1008942986 3210 dbSNP
rs1207342597 3218 dbSNP
rs890250887 3221 dbSNP
rs750197795 3227 dbSNP
rs928355815 3228 dbSNP
rs1270737898 3241 dbSNP
rs532179317 3244 dbSNP
rs1356700010 3245 dbSNP
rs1294894843 3254 dbSNP
rs1026745504 3260 dbSNP
rs1411816441 3264 dbSNP
rs973884611 3264 dbSNP
rs1349883689 3271 dbSNP
rs899982325 3273 dbSNP
rs963889154 3277 dbSNP
rs550739125 3278 dbSNP
rs757045998 3280 dbSNP
rs1322752221 3288 dbSNP
rs757140480 3289 dbSNP
rs753790312 3290 dbSNP
rs936278184 3293 dbSNP
rs924821381 3294 dbSNP
rs1205359611 3295 dbSNP
rs764097865 3297 dbSNP
rs950091817 3301 dbSNP
rs373589107 3303 dbSNP
rs760743661 3307 dbSNP
rs866130402 3309 dbSNP
rs577081040 3310 dbSNP
rs558827091 3311 dbSNP
rs537624416 3312 dbSNP
rs1370075288 3313 dbSNP
rs973610831 3316 dbSNP
rs895356644 3320 dbSNP
rs1380526159 3322 dbSNP
rs1056723594 3324 dbSNP
rs1412923904 3325 dbSNP
rs1344703085 3326 dbSNP
rs1228728364 3328 dbSNP
rs1184639812 3338 dbSNP
rs1435617363 3338 dbSNP
rs570167229 3340 dbSNP
rs939648599 3345 dbSNP
rs1222486908 3347 dbSNP
rs1181613937 3350 dbSNP
rs774739940 3352 dbSNP
rs1452092707 3353 dbSNP
rs961990543 3354 dbSNP
rs1449804259 3357 dbSNP
rs1169518821 3359 dbSNP
rs928265163 3365 dbSNP
rs1015255577 3366 dbSNP
rs1008600142 3368 dbSNP
rs1268309061 3371 dbSNP
rs181713648 3375 dbSNP
rs538978709 3378 dbSNP
rs1278434576 3379 dbSNP
rs1436243974 3380 dbSNP
rs376870549 3381 dbSNP
rs549350977 3385 dbSNP
rs1054635920 3386 dbSNP
rs973830754 3387 dbSNP
rs531928480 3399 dbSNP
rs532157279 3400 dbSNP
rs1161555801 3404 dbSNP
rs866155339 3405 dbSNP
rs1131924 3407 dbSNP
rs987102551 3410 dbSNP
rs11030034 3411 dbSNP
rs1479068783 3412 dbSNP
rs999542052 3413 dbSNP
rs1221141129 3415 dbSNP
rs531500139 3416 dbSNP
rs1329782611 3417 dbSNP
rs1207971098 3419 dbSNP
rs1042353590 3420 dbSNP
rs1191687494 3424 dbSNP
rs189336240 3425 dbSNP
rs1480181463 3427 dbSNP
rs200303794 3434 dbSNP
rs917268659 3443 dbSNP
rs1012372801 3444 dbSNP
rs1473211846 3447 dbSNP
rs895304149 3448 dbSNP
rs1056658159 3452 dbSNP
rs527837354 3454 dbSNP
rs560401612 3455 dbSNP
rs373373670 3460 dbSNP
rs771713538 3464 dbSNP
rs1402643709 3471 dbSNP
rs12418317 3478 dbSNP
rs3209593 3479 dbSNP
rs879580610 3480 dbSNP
rs185002890 3486 dbSNP
rs1038069550 3494 dbSNP
rs767192682 3499 dbSNP
rs911034679 3503 dbSNP
rs942474386 3503 dbSNP
rs907815726 3511 dbSNP
rs987778319 3515 dbSNP
rs192518520 3533 dbSNP
rs757051946 3534 dbSNP
rs1028674811 3535 dbSNP
rs576554729 3550 dbSNP
rs759095433 3553 dbSNP
rs180685048 3554 dbSNP
rs536334723 3557 dbSNP
rs1472935286 3560 dbSNP
rs923885907 3564 dbSNP
rs1032504092 3565 dbSNP
rs1474017512 3566 dbSNP
rs1164204414 3570 dbSNP
rs1384940440 3571 dbSNP
rs1000403364 3576 dbSNP
rs1422388083 3578 dbSNP
rs753706085 3579 dbSNP
rs770242655 3581 dbSNP
rs1390293651 3583 dbSNP
rs968034624 3586 dbSNP
rs11553662 3589 dbSNP
rs903336201 3599 dbSNP
rs11030033 3605 dbSNP
rs1356943387 3606 dbSNP
rs1264064887 3609 dbSNP
rs1393355880 3612 dbSNP
rs1173168948 3615 dbSNP
rs1195298512 3623 dbSNP
rs1453713366 3632 dbSNP
rs140717423 3634 dbSNP
rs1014473756 3642 dbSNP
rs538612477 3643 dbSNP
rs1188014186 3645 dbSNP
rs571282498 3648 dbSNP
rs1188797259 3654 dbSNP
rs1242955025 3656 dbSNP
rs1484789748 3658 dbSNP
rs896038584 3659 dbSNP
rs1241108531 3662 dbSNP
rs773412486 3662 dbSNP
rs1210402876 3663 dbSNP
rs1035564044 3664 dbSNP
rs550033756 3665 dbSNP
rs1003716035 3679 dbSNP
rs188323101 3682 dbSNP
rs1396556315 3685 dbSNP
rs1232998775 3691 dbSNP
rs937340188 3703 dbSNP
rs1298419955 3707 dbSNP
rs1213133170 3708 dbSNP
rs756058836 3709 dbSNP
rs1303579192 3716 dbSNP
rs1308306457 3719 dbSNP
rs1047966724 3732 dbSNP
rs1416853942 3733 dbSNP
rs752794414 3740 dbSNP
rs1347167399 3742 dbSNP
rs1201572893 3756 dbSNP
rs1243049242 3765 dbSNP
rs118172994 3777 dbSNP
rs1312329901 3778 dbSNP
rs759744388 3789 dbSNP
rs1190898689 3791 dbSNP
rs1248959297 3811 dbSNP
rs1430532840 3813 dbSNP
rs1190513255 3822 dbSNP
rs1373532682 3825 dbSNP
rs1466076431 3830 dbSNP
rs1175680021 3840 dbSNP
rs898145980 3852 dbSNP
rs1172473429 3853 dbSNP
rs1458688303 3855 dbSNP
rs1038017063 3859 dbSNP
rs1360954264 3863 dbSNP
rs1381898193 3865 dbSNP
rs147244393 3880 dbSNP
rs1332961007 3883 dbSNP
rs1418533373 3887 dbSNP
rs1224192163 3888 dbSNP
rs907720821 3890 dbSNP
rs3763966 3891 dbSNP
rs954617113 3894 dbSNP
rs1261697787 3898 dbSNP
rs1255017071 3901 dbSNP
rs1203047349 3910 dbSNP
rs1209486119 3919 dbSNP
rs1483112554 3922 dbSNP
rs559392209 3926 dbSNP
rs751833233 3934 dbSNP
rs184511176 3943 dbSNP
rs532353717 3944 dbSNP
rs1159766228 3945 dbSNP
rs1307493914 3946 dbSNP
rs923805839 3949 dbSNP
rs1313871059 3957 dbSNP
rs921803970 3958 dbSNP
rs1287400455 3959 dbSNP
rs1393146709 3974 dbSNP
rs1405711278 3975 dbSNP
rs1235586719 3978 dbSNP
rs1230804275 3984 dbSNP
rs1353764652 3993 dbSNP
rs978022628 3998 dbSNP
rs1292940679 4006 dbSNP
rs1214073685 4011 dbSNP
rs766770552 4012 dbSNP
rs564964477 4019 dbSNP
rs915222280 4022 dbSNP
rs1266191628 4032 dbSNP
rs142020039 4032 dbSNP
rs1483733251 4036 dbSNP
rs1032120518 4040 dbSNP
rs1182875140 4045 dbSNP
rs1299746841 4046 dbSNP
rs1407151120 4047 dbSNP
rs959405138 4053 dbSNP
rs192905631 4062 dbSNP
rs1035107708 4072 dbSNP
rs1460398757 4074 dbSNP
rs1368763979 4078 dbSNP
rs1425555878 4080 dbSNP
rs966458707 4092 dbSNP
rs1020881198 4095 dbSNP
rs1411714938 4097 dbSNP
rs1299302053 4098 dbSNP
rs1014336555 4102 dbSNP
rs1373241153 4104 dbSNP
rs896112016 4107 dbSNP
rs1055966765 4108 dbSNP
rs1315296981 4114 dbSNP
rs1001521605 4117 dbSNP
rs899144209 4118 dbSNP
rs1476087045 4119 dbSNP
rs1244843872 4124 dbSNP
rs1037686892 4126 dbSNP
rs1343753078 4127 dbSNP
rs542844381 4128 dbSNP
rs544090352 4137 dbSNP
rs763393024 4138 dbSNP
rs1479622719 4144 dbSNP
rs899440360 4151 dbSNP
rs1016523373 4153 dbSNP
rs1472597000 4153 dbSNP
rs777595817 4153 dbSNP
rs1443752669 4160 dbSNP
rs1163234849 4164 dbSNP
rs1383605685 4168 dbSNP
rs1431780153 4170 dbSNP
rs576702536 4194 dbSNP
rs933136226 4201 dbSNP
rs1440688959 4208 dbSNP
rs921878743 4211 dbSNP
rs1305077369 4230 dbSNP
rs974643934 4231 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 55327.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' ucgACAAGGACGACuu 5'
             | |  ||||||  
Target 5' ucaUUUAGCUGCUG-- 3'
 		7 - 20
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000278193.2 | 3UTR | UUUUCUUCAUUUAGCUGCUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
82 hsa-miR-4291 Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT102445 CALU calumenin 2 4
MIRT108677 ZBTB33 zinc finger and BTB domain containing 33 2 4
MIRT125969 SHOC2 SHOC2, leucine rich repeat scaffold protein 2 6
MIRT179018 PAFAH1B2 platelet activating factor acetylhydrolase 1b catalytic subunit 2 2 4
MIRT379033 CDK6 cyclin dependent kinase 6 2 6
MIRT442473 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 2
MIRT442910 PCBD2 pterin-4 alpha-carbinolamine dehydratase 2 2 2
MIRT442979 ZNF736 zinc finger protein 736 2 2
MIRT445663 TNFSF15 TNF superfamily member 15 2 2
MIRT446237 FZD6 frizzled class receptor 6 2 2
MIRT448860 FAM49B family with sequence similarity 49 member B 2 2
MIRT455559 TRAF1 TNF receptor associated factor 1 2 2
MIRT459704 ZNF641 zinc finger protein 641 2 2
MIRT460608 FEM1A fem-1 homolog A 2 2
MIRT462251 LAMA4 laminin subunit alpha 4 2 2
MIRT462469 FIZ1 FLT3 interacting zinc finger 1 2 2
MIRT466656 TAF1D TATA-box binding protein associated factor, RNA polymerase I subunit D 2 6
MIRT466841 STX6 syntaxin 6 2 2
MIRT471403 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT471517 PCGF3 polycomb group ring finger 3 2 2
MIRT471681 PABPN1 poly(A) binding protein nuclear 1 2 2
MIRT472858 MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2 2
MIRT474813 KIAA0226 RUN and cysteine rich domain containing beclin 1 interacting protein 2 2
MIRT474931 KCTD15 potassium channel tetramerization domain containing 15 2 2
MIRT475814 HDGF heparin binding growth factor 2 2
MIRT480434 C17orf49 chromosome 17 open reading frame 49 2 2
MIRT480903 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough 2 2
MIRT481478 ARL8B ADP ribosylation factor like GTPase 8B 2 2
MIRT484982 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 8
MIRT485019 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 8
MIRT485036 TMEM189 transmembrane protein 189 2 8
MIRT495074 HEYL hes related family bHLH transcription factor with YRPW motif-like 2 2
MIRT496004 CD180 CD180 molecule 2 2
MIRT500675 TRIM37 tripartite motif containing 37 2 2
MIRT504544 ZNF417 zinc finger protein 417 2 6
MIRT506782 KLHL15 kelch like family member 15 2 6
MIRT507256 FGF2 fibroblast growth factor 2 2 6
MIRT507386 EN2 engrailed homeobox 2 2 2
MIRT512505 BTBD19 BTB domain containing 19 2 2
MIRT516903 CTSB cathepsin B 2 2
MIRT528124 PPP1R10 protein phosphatase 1 regulatory subunit 10 2 2
MIRT528874 ATF3 activating transcription factor 3 2 2
MIRT536091 MBOAT2 membrane bound O-acyltransferase domain containing 2 2 2
MIRT541079 RLIM ring finger protein, LIM domain interacting 2 2
MIRT541099 RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2 2
MIRT545360 LIN7C lin-7 homolog C, crumbs cell polarity complex component 2 2
MIRT545831 ZNF367 zinc finger protein 367 2 4
MIRT547115 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 2
MIRT547312 NPTN neuroplastin 2 2
MIRT547959 HIGD1A HIG1 hypoxia inducible domain family member 1A 2 4
MIRT549943 RPL7L1 ribosomal protein L7 like 1 2 2
MIRT550749 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 2 2
MIRT565145 TUBB2A tubulin beta 2A class IIa 2 2
MIRT571050 POLQ DNA polymerase theta 2 2
MIRT571361 ZNF45 zinc finger protein 45 2 2
MIRT610133 FOXI2 forkhead box I2 2 2
MIRT613145 DSE dermatan sulfate epimerase 2 2
MIRT613379 ABCC12 ATP binding cassette subfamily C member 12 2 2
MIRT615752 C6 complement C6 2 2
MIRT616460 ADRA2B adrenoceptor alpha 2B 2 2
MIRT616719 FEM1B fem-1 homolog B 2 2
MIRT618312 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT631491 RASSF4 Ras association domain family member 4 2 2
MIRT643134 PLCXD2 phosphatidylinositol specific phospholipase C X domain containing 2 2 2
MIRT643482 DISC1 disrupted in schizophrenia 1 2 2
MIRT649715 TWSG1 twisted gastrulation BMP signaling modulator 1 2 2
MIRT653542 SLC38A7 solute carrier family 38 member 7 2 2
MIRT666307 SLC22A3 solute carrier family 22 member 3 2 2
MIRT692005 NAP1L4 nucleosome assembly protein 1 like 4 2 2
MIRT696838 ARL2BP ADP ribosylation factor like GTPase 2 binding protein 2 2
MIRT698204 TMEM248 transmembrane protein 248 2 2
MIRT703316 GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2 2
MIRT709376 FAM13A family with sequence similarity 13 member A 2 2
MIRT710112 MED23 mediator complex subunit 23 2 2
MIRT711975 HOMER2 homer scaffolding protein 2 2 2
MIRT712275 PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2 2
MIRT714108 TMED9 transmembrane p24 trafficking protein 9 2 2
MIRT719113 MAML1 mastermind like transcriptional coactivator 1 2 2
MIRT719727 SLC39A11 solute carrier family 39 member 11 2 2
MIRT720018 TFAP2C transcription factor AP-2 gamma 2 2
MIRT720358 ZBTB8B zinc finger and BTB domain containing 8B 2 2
MIRT720372 NUDT3 nudix hydrolase 3 2 2
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-4 Dexamethasone approved 5743 Microarray primary rat thymocytes 20847043 2010 up-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4291 Platinum-based doublet chemotherapy resistant High Lung Adenocarcinoma tissue
hsa-miR-4291 Platinum 23939 resistant High Ovarian Cancer tissue
hsa-miR-4291 Paclitaxel 36314 NSC125973 approved resistant High Prostate Cancer cell line (DU-145, PC-3)
hsa-miR-4291 Doxorubicin 31703 NSC123127 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-4291 Radioactivity Iodine resistant High Papillary Thyroid Cancer tissue
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved resistant High Hypopharyngeal Cancer cell line (FaDu)
hsa-miR-4291 Gefitinib 123631 NSC715055 approved resistant cell line (PC9)
hsa-miR-4291 Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved sensitive cell line (CAL-27) (cytosolic RNA)
hsa-miR-4291 Osimertinib 71496458 NSC779217 approved sensitive cell line (H1975)
hsa-miR-4291 Platinum-based doublet chemotherapy resistant tissue (lung adenocarcinoma)
hsa-miR-4291 Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-4291 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR3)
hsa-miR-4291 Gemcitabine 60750 NSC613327 approved resistant cell line (Panc1-GR4)

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