pre-miRNA Information
pre-miRNA hsa-mir-367   
Genomic Coordinates chr4: 112647874 - 112647941
Synonyms MIRN367, hsa-mir-367, MIR367
Description Homo sapiens miR-367 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-367-3p
Sequence 44| AAUUGCACUUUAGCAAUGGUGA |65
Evidence Experimental
Experiments Cloned
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN24411246 17 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs535597757 1 dbSNP
rs1013348949 11 dbSNP
rs896333735 12 dbSNP
rs751269136 14 dbSNP
rs1163501507 16 dbSNP
rs757092597 21 dbSNP
Putative Targets

Gene Information
Gene Symbol WDR81   
Synonyms CAMRQ2, PPP1R166, SORF-2
Description WD repeat domain 81
Transcript NM_001163673   
Other Transcripts NM_001163809 , NM_001163811 , NM_152348   
Expression
Putative miRNA Targets on WDR81
3'UTR of WDR81
(miRNA target sites are highlighted)
>WDR81|NM_001163673|3'UTR
   1 ACTGAGGCAGGAGCTGGCCGGGCAAGGGTGGGAAGACATCTGCGGGCGCGTGTCCACTCACCCTGTTCCCTGAGCAGCAG
  81 CTCCCTCCAGGGAGGCCCTGGGTCCCACGCCCTGGGTGCCCACATGGCCTGCCAACTAGGGCCTGCAAATGGAGTGGGGG
 161 AGTCCTGGCCCCTGAATCACCAGAGCCACCAAGCCTGCCAGAGGGGTCTCATTCATGGCTTGGGGACACAGGGCTCCTAG
 241 CAAGCAGGAAGTTAAGAGCAGGAGGAAGCGTTGCTACCTTCACTTCTCCCCAGCTCTGCCCTCTGGGTCCACATGAGGAC
 321 AGGGAAGCTCGGGAAGGGGAAGGGAGACTGGCCCTGCCCAGCCGGTCTCTAGCCCCTCAGCCCCCGCTGGGCACTCTCTG
 401 TCCCATCCCTCTAGGACAGGGAAGCTGGCCTGGTCCAGGGCACTGATGGTGCTTGGATTCCAGCCTAAGGAAGGCTGGCC
 481 GTGGTCCAGGAGTTAAGGGCTTGGGTCTGGGGTTTAAGTGGCCACCCATCCAGGCCCTGGCCAGTGTGGGACCGGGACGG
 561 GAAGGAAGAAGGAGGCTAGGAGCAGGGGGAAAAGGTGCACTTGGCCAGTGGCGCCTGCCAGGAGTGAGTCCATGCGTTGT
 641 CTGCCCACCCCTACCACAGTGTTTGTGCCTTCAGCTGAGGGGGCAGCCTCTGGGCCCTGAACCCCTGCTGGGGCTCCACG
 721 ACCCTGAGAGAAGGGGTGAGAAGAATCATCTCTGCACCTCGGGTCTCTGCCAGAGGAAGACTTAAGCATCCCTGCGACCT
 801 CACATTCTAGACAGAGATGAGGTCCAGGGGTTGGCCCCTGCTGCCTTCTCACAATTTGCAATAGATGTAAATAGGACCAA
 881 TAAATCCTTTGGAAGAGCCATGGGGTGAACTGAG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' agugguaacgaUUUCACGUUAa 5'
                     ||:||||| | 
Target 5' agcagggggaaAAGGTGCACTt 3'
581 - 602 119.00 -7.50
2
miRNA  3' agugguaacgauuucACGUUaa 5'
                         |||||  
Target 5' ctgccaactagggccTGCAAat 3'
129 - 150 100.00 -9.10
3
miRNA  3' aguGGUAACGAUUUCACGUUAa 5'
             || |||  :||| || || 
Target 5' aatCCTTTG--GAAGAGCCATg 3'
883 - 902 99.00 -5.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
1185335 57 ClinVar
COSN30506739 10 COSMIC
COSN17164317 45 COSMIC
COSN30539211 53 COSMIC
COSN30451030 56 COSMIC
COSN6653339 57 COSMIC
COSN31488457 175 COSMIC
COSN8832338 176 COSMIC
COSN31488364 204 COSMIC
COSN8393514 266 COSMIC
COSN24967912 355 COSMIC
COSN31609053 425 COSMIC
COSN31557527 470 COSMIC
COSN31597090 481 COSMIC
COSN31607922 558 COSMIC
COSN30174659 582 COSMIC
COSN28685916 586 COSMIC
COSN31487258 627 COSMIC
COSN16127642 678 COSMIC
COSN31529978 731 COSMIC
COSN16127532 741 COSMIC
COSN16127560 761 COSMIC
COSN16127650 815 COSMIC
COSN31488269 820 COSMIC
COSN6653343 828 COSMIC
COSN31523333 841 COSMIC
rs2287322 57 GWAS
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs758278135 3 dbSNP
rs896237078 8 dbSNP
rs779847715 12 dbSNP
rs746828815 15 dbSNP
rs1346526023 16 dbSNP
rs373156614 20 dbSNP
rs748224837 21 dbSNP
rs769845680 23 dbSNP
rs773179350 24 dbSNP
rs1286565415 26 dbSNP
rs560335168 30 dbSNP
rs750082551 30 dbSNP
rs1447756145 31 dbSNP
rs1356441142 33 dbSNP
rs1187132120 35 dbSNP
rs1236626430 36 dbSNP
rs1442552144 38 dbSNP
rs551272368 39 dbSNP
rs774669884 42 dbSNP
rs887458802 43 dbSNP
rs759946368 44 dbSNP
rs753558489 45 dbSNP
rs1169962518 46 dbSNP
rs764744022 47 dbSNP
rs144638864 48 dbSNP
rs375681186 49 dbSNP
rs374841920 50 dbSNP
rs186162259 51 dbSNP
rs1030617768 56 dbSNP
rs2287322 57 dbSNP
rs906762205 63 dbSNP
rs1233460592 64 dbSNP
rs1335923814 68 dbSNP
rs1249869178 69 dbSNP
rs1003823398 71 dbSNP
rs1449964991 89 dbSNP
rs534508606 102 dbSNP
rs557481891 103 dbSNP
rs1169516513 109 dbSNP
rs988900046 110 dbSNP
rs1033668749 117 dbSNP
rs1462226146 119 dbSNP
rs577423320 125 dbSNP
rs1162585224 141 dbSNP
rs994839647 149 dbSNP
rs1364340953 153 dbSNP
rs1467266058 157 dbSNP
rs1183835917 159 dbSNP
rs1416801918 162 dbSNP
rs752192166 165 dbSNP
rs980120579 171 dbSNP
rs147897034 179 dbSNP
rs938972960 193 dbSNP
rs1321933044 195 dbSNP
rs1368011048 198 dbSNP
rs573214180 204 dbSNP
rs755595711 205 dbSNP
rs1302080980 211 dbSNP
rs918760182 220 dbSNP
rs777154276 232 dbSNP
rs879486744 250 dbSNP
rs557243878 252 dbSNP
rs1241720097 257 dbSNP
rs1334504562 260 dbSNP
rs754331793 261 dbSNP
rs887551104 270 dbSNP
rs117022317 271 dbSNP
rs190097774 272 dbSNP
rs1038709473 274 dbSNP
rs1397006538 275 dbSNP
rs900414643 278 dbSNP
rs997844912 291 dbSNP
rs1404569383 292 dbSNP
rs3826539 298 dbSNP
rs956079073 299 dbSNP
rs1160233964 316 dbSNP
rs1010300419 326 dbSNP
rs746301099 331 dbSNP
rs974597339 332 dbSNP
rs1201891096 338 dbSNP
rs968816465 343 dbSNP
rs1192563151 351 dbSNP
rs921606205 352 dbSNP
rs1025121801 357 dbSNP
rs980097899 364 dbSNP
rs573328721 365 dbSNP
rs1285891355 372 dbSNP
rs182794413 379 dbSNP
rs1373222016 380 dbSNP
rs565445283 382 dbSNP
rs913008804 384 dbSNP
rs918740390 385 dbSNP
rs531157683 386 dbSNP
rs1042577555 387 dbSNP
rs1428213682 388 dbSNP
rs1359869486 391 dbSNP
rs550589667 393 dbSNP
rs1436071871 394 dbSNP
rs939588526 394 dbSNP
rs1171479060 396 dbSNP
rs1388651815 402 dbSNP
rs561663469 406 dbSNP
rs1243466762 408 dbSNP
rs1195831771 413 dbSNP
rs1055342405 416 dbSNP
rs908957516 421 dbSNP
rs1350146657 425 dbSNP
rs1454764105 426 dbSNP
rs1278374833 428 dbSNP
rs1288861735 436 dbSNP
rs941823033 438 dbSNP
rs1340385786 439 dbSNP
rs994870675 449 dbSNP
rs1428422887 455 dbSNP
rs534075635 456 dbSNP
rs548616433 461 dbSNP
rs1313425546 466 dbSNP
rs900174553 469 dbSNP
rs1416472734 478 dbSNP
rs370504275 481 dbSNP
rs112099834 482 dbSNP
rs1410008239 500 dbSNP
rs1421245327 505 dbSNP
rs891733099 507 dbSNP
rs768738601 510 dbSNP
rs1010058383 519 dbSNP
rs974545301 524 dbSNP
rs1028900770 525 dbSNP
rs1189085445 527 dbSNP
rs957271842 533 dbSNP
rs989855185 536 dbSNP
rs1209562703 538 dbSNP
rs912865435 554 dbSNP
rs534372781 555 dbSNP
rs551074128 559 dbSNP
rs1293740730 560 dbSNP
rs1215141581 573 dbSNP
rs928118237 575 dbSNP
rs1353528103 577 dbSNP
rs776591866 580 dbSNP
rs1442323937 584 dbSNP
rs1055289458 586 dbSNP
rs1326448231 588 dbSNP
rs1464837608 591 dbSNP
rs1034327929 595 dbSNP
rs1166167958 601 dbSNP
rs1476375318 610 dbSNP
rs960332742 613 dbSNP
rs762923110 614 dbSNP
rs1026303947 619 dbSNP
rs569006864 625 dbSNP
rs148963581 629 dbSNP
rs1457521781 630 dbSNP
rs1274007876 633 dbSNP
rs951666630 635 dbSNP
rs116026578 636 dbSNP
rs1319649694 636 dbSNP
rs796545171 637 dbSNP
rs1224201057 638 dbSNP
rs1375435671 642 dbSNP
rs1277321404 644 dbSNP
rs1445378477 648 dbSNP
rs1049073647 649 dbSNP
rs886405713 651 dbSNP
rs141905948 652 dbSNP
rs1348442740 658 dbSNP
rs1019486515 660 dbSNP
rs941749670 665 dbSNP
rs974911138 666 dbSNP
rs995994007 669 dbSNP
rs1459858432 673 dbSNP
rs1176894859 679 dbSNP
rs921588406 680 dbSNP
rs1028763661 691 dbSNP
rs879430249 698 dbSNP
rs1253891067 700 dbSNP
rs142610446 705 dbSNP
rs1365272840 706 dbSNP
rs990443345 709 dbSNP
rs1264707932 710 dbSNP
rs1403487123 712 dbSNP
rs1290508777 713 dbSNP
rs1283763317 715 dbSNP
rs77361038 720 dbSNP
rs891707885 721 dbSNP
rs1347915369 725 dbSNP
rs536643499 726 dbSNP
rs1438176739 728 dbSNP
rs375278261 729 dbSNP
rs904372943 731 dbSNP
rs1310 737 dbSNP
rs1223056271 745 dbSNP
rs1347494406 745 dbSNP
rs1157331138 748 dbSNP
rs533578042 753 dbSNP
rs1395692111 757 dbSNP
rs1175591793 758 dbSNP
rs116042891 761 dbSNP
rs1419045043 762 dbSNP
rs991005968 763 dbSNP
rs866709777 766 dbSNP
rs1486702624 768 dbSNP
rs750898000 769 dbSNP
rs1025684355 775 dbSNP
rs371543660 784 dbSNP
rs1347979577 785 dbSNP
rs753339794 787 dbSNP
rs1480087004 793 dbSNP
rs1174999855 795 dbSNP
rs951591796 796 dbSNP
rs565407963 797 dbSNP
rs1215545534 802 dbSNP
rs1342706541 807 dbSNP
rs1426083638 809 dbSNP
rs984345566 813 dbSNP
rs757753213 814 dbSNP
rs964196777 817 dbSNP
rs1045806 828 dbSNP
rs921663438 830 dbSNP
rs1464584518 831 dbSNP
rs1385146214 833 dbSNP
rs1377318356 834 dbSNP
rs1171341798 837 dbSNP
rs940721607 846 dbSNP
rs933116154 853 dbSNP
rs1423185896 855 dbSNP
rs1485992527 860 dbSNP
rs1259503980 862 dbSNP
rs559168746 867 dbSNP
rs1482615694 875 dbSNP
rs1355368767 877 dbSNP
rs1206098948 881 dbSNP
rs987505556 884 dbSNP
rs912911739 888 dbSNP
rs945920237 890 dbSNP
rs1043015776 899 dbSNP
rs1050233054 900 dbSNP
rs904464360 901 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 124997.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000437219.2 | 3UTR | CUGCCUUCUCACAAUUUGCAAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000437219.2 | 3UTR | CUGCCUUCUCACAAUUUGCAAUAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
GSE28260 Renal cortex and medulla -0.632 1.0e-2 -0.463 5.6e-2 13 Click to see details
GSE28544 Breast cancer -0.387 3.1e-2 -0.385 3.2e-2 24 Click to see details
GSE38226 Liver fibrosis -0.33 7.2e-2 -0.323 7.7e-2 21 Click to see details
GSE19350 CNS germ cell tumors -0.417 8.9e-2 -0.343 1.4e-1 12 Click to see details
GSE32688 Pancreatic cancer -0.199 1.4e-1 -0.288 5.5e-2 32 Click to see details
GSE42095 Differentiated embryonic stem cells -0.158 2.4e-1 -0.089 3.4e-1 23 Click to see details
GSE17306 Multiple myeloma 0.093 2.6e-1 0.469 3.4e-4 49 Click to see details
GSE21687 Ependynoma primary tumors -0.074 2.8e-1 -0.056 3.3e-1 64 Click to see details
GSE27834 Pluripotent stem cells -0.151 2.9e-1 -0.035 4.5e-1 16 Click to see details
GSE14794 Lymphoblastoid cells -0.038 3.6e-1 -0.018 4.3e-1 90 Click to see details
GSE21849 B cell lymphoma 0.027 4.4e-1 0.135 2.4e-1 29 Click to see details
GSE26953 Aortic valvular endothelial cells -0.017 4.7e-1 0.042 4.2e-1 24 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.004 4.9e-1 0.209 1.9e-1 20 Click to see details
GSE34608 Pulmonary tuberculosis and sarcoidosis 0.004 4.9e-1 0.209 1.9e-1 20 Click to see details
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
255 hsa-miR-367-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055315 DUSP5 dual specificity phosphatase 5 2 8
MIRT055791 PLEKHA1 pleckstrin homology domain containing A1 2 12
MIRT057114 DDIT4 DNA damage inducible transcript 4 2 4
MIRT059663 GATAD2B GATA zinc finger domain containing 2B 2 2
MIRT059926 ZDHHC5 zinc finger DHHC-type containing 5 2 2
MIRT061610 BTG2 BTG anti-proliferation factor 2 2 6
MIRT066478 HMGA2 high mobility group AT-hook 2 2 2
MIRT069388 ZFYVE21 zinc finger FYVE-type containing 21 2 2
MIRT069972 GEMIN2 gem nuclear organelle associated protein 2 2 2
MIRT074764 CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 2 2
MIRT076199 GID4 GID complex subunit 4 homolog 2 6
MIRT077512 UBE2Z ubiquitin conjugating enzyme E2 Z 2 4
MIRT077903 TOB1 transducer of ERBB2, 1 2 6
MIRT082250 MED29 mediator complex subunit 29 2 4
MIRT082434 CIC capicua transcriptional repressor 2 6
MIRT082474 PPP1R37 protein phosphatase 1 regulatory subunit 37 2 2
MIRT082778 ZNF264 zinc finger protein 264 2 2
MIRT084533 BCL2L11 BCL2 like 11 2 8
MIRT085309 UBXN4 UBX domain protein 4 2 8
MIRT086365 SSFA2 sperm specific antigen 2 2 8
MIRT087455 NF2 neurofibromin 2 2 2
MIRT088865 FOXN2 forkhead box N2 2 12
MIRT092185 ITPR1 inositol 1,4,5-trisphosphate receptor type 1 2 6
MIRT092326 EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 2 6
MIRT093533 GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 2 6
MIRT096935 PAPD7 poly(A) RNA polymerase D7, non-canonical 2 8
MIRT097026 MAP1B microtubule associated protein 1B 2 4
MIRT099137 MYLIP myosin regulatory light chain interacting protein 2 6
MIRT099905 SOX4 SRY-box 4 2 12
MIRT102289 DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 2 10
MIRT102507 KLHDC10 kelch domain containing 10 2 2
MIRT102891 INSIG1 insulin induced gene 1 2 2
MIRT109188 VMA21 VMA21, vacuolar ATPase assembly factor 2 4
MIRT124567 PRRC2B proline rich coiled-coil 2B 2 2
MIRT135568 SPRYD4 SPRY domain containing 4 2 2
MIRT161135 SLC25A36 solute carrier family 25 member 36 2 6
MIRT163995 KIAA1109 KIAA1109 2 4
MIRT164689 RNF4 ring finger protein 4 2 2
MIRT167705 HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2 8
MIRT178956 USP28 ubiquitin specific peptidase 28 2 2
MIRT185717 ARNTL2 aryl hydrocarbon receptor nuclear translocator like 2 2 2
MIRT186264 TCEB3 elongin A 2 2
MIRT186537 TWF1 twinfilin actin binding protein 1 2 4
MIRT186628 COX20 COX20, cytochrome c oxidase assembly factor 2 8
MIRT189373 TXLNA taxilin alpha 2 4
MIRT197013 EIF1 eukaryotic translation initiation factor 1 2 10
MIRT206437 YIPF4 Yip1 domain family member 4 2 2
MIRT211228 FGF2 fibroblast growth factor 2 2 10
MIRT214529 C5ORF24 chromosome 5 open reading frame 24 2 2
MIRT216034 IL6ST interleukin 6 signal transducer 2 10
MIRT218084 TULP4 tubby like protein 4 2 2
MIRT242418 CCDC113 coiled-coil domain containing 113 2 2
MIRT243162 SOX11 SRY-box 11 2 2
MIRT250943 CDK5R1 cyclin dependent kinase 5 regulatory subunit 1 2 4
MIRT253350 ZNF417 zinc finger protein 417 2 2
MIRT271968 ARF1 ADP ribosylation factor 1 2 2
MIRT273214 ZNF695 zinc finger protein 695 2 4
MIRT296114 SLC12A5 solute carrier family 12 member 5 2 2
MIRT301711 TEF TEF, PAR bZIP transcription factor 2 2
MIRT316477 ARID1B AT-rich interaction domain 1B 2 6
MIRT322174 CLN8 CLN8, transmembrane ER and ERGIC protein 2 4
MIRT341538 CNIH1 cornichon family AMPA receptor auxiliary protein 1 2 6
MIRT356062 SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 2 2
MIRT443579 PPIC peptidylprolyl isomerase C 2 2
MIRT448825 FKBP1A FK506 binding protein 1A 2 4
MIRT451494 FOPNL FGFR1OP N-terminal like 2 2
MIRT452694 MDM2 MDM2 proto-oncogene 2 2
MIRT453167 CNOT4 CCR4-NOT transcription complex subunit 4 2 6
MIRT454588 SLC33A1 solute carrier family 33 member 1 2 4
MIRT455794 TAF8 TATA-box binding protein associated factor 8 2 4
MIRT456010 CYP2C19 cytochrome P450 family 2 subfamily C member 19 2 2
MIRT456044 KIAA1586 KIAA1586 2 2
MIRT456763 TMEM239 transmembrane protein 239 2 4
MIRT458068 NLRP9 NLR family pyrin domain containing 9 2 2
MIRT459230 MRPS21 mitochondrial ribosomal protein S21 2 2
MIRT459534 MFF mitochondrial fission factor 2 6
MIRT459759 SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 2 2
MIRT460236 TNFRSF13C TNF receptor superfamily member 13C 2 2
MIRT461104 OPA3 OPA3, outer mitochondrial membrane lipid metabolism regulator 2 2
MIRT462924 ZNRF3 zinc and ring finger 3 2 2
MIRT463476 ZC3HAV1L zinc finger CCCH-type containing, antiviral 1 like 2 2
MIRT463516 ZBTB8B zinc finger and BTB domain containing 8B 2 4
MIRT465503 TOR1B torsin family 1 member B 2 2
MIRT469525 RBFOX2 RNA binding protein, fox-1 homolog 2 2 8
MIRT470079 PTGES2 prostaglandin E synthase 2 2 2
MIRT471581 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT473451 MCOLN2 mucolipin 2 2 8
MIRT475882 H3F3C H3 histone family member 3C 2 10
MIRT475915 H3F3B H3 histone family member 3B 2 8
MIRT476195 GOLGA8A golgin A8 family member A 2 10
MIRT476318 GM2A GM2 ganglioside activator 2 2
MIRT476676 FUT11 fucosyltransferase 11 2 10
MIRT478368 DDI2 DNA damage inducible 1 homolog 2 2 2
MIRT479545 CDC5L cell division cycle 5 like 2 2
MIRT481024 BAZ2B bromodomain adjacent to zinc finger domain 2B 2 2
MIRT491009 ATF7IP activating transcription factor 7 interacting protein 2 2
MIRT493168 MKNK2 MAP kinase interacting serine/threonine kinase 2 2 2
MIRT494345 CASKIN1 CASK interacting protein 1 2 2
MIRT499087 ZDHHC21 zinc finger DHHC-type containing 21 2 6
MIRT500029 ABCF2 ATP binding cassette subfamily F member 2 2 8
MIRT501298 RRN3 RRN3 homolog, RNA polymerase I transcription factor 2 4
MIRT503124 BCL11B B-cell CLL/lymphoma 11B 2 8
MIRT503301 GTF2A1 general transcription factor IIA subunit 1 2 6
MIRT504328 ASGR2 asialoglycoprotein receptor 2 2 6
MIRT504471 EID2B EP300 interacting inhibitor of differentiation 2B 2 2
MIRT504655 RPL9 ribosomal protein L9 2 6
MIRT505331 TMF1 TATA element modulatory factor 1 2 8
MIRT505732 SERTAD3 SERTA domain containing 3 2 4
MIRT505827 RSBN1 round spermatid basic protein 1 2 8
MIRT506004 PURG purine rich element binding protein G 2 8
MIRT506308 PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 2 6
MIRT506806 KLHL15 kelch like family member 15 2 6
MIRT507119 GOLGA8B golgin A8 family member B 2 6
MIRT507353 FAM129A family with sequence similarity 129 member A 2 6
MIRT507591 DDX3X DEAD-box helicase 3, X-linked 2 4
MIRT507674 CPEB4 cytoplasmic polyadenylation element binding protein 4 2 4
MIRT507703 CNOT2 CCR4-NOT transcription complex subunit 2 2 8
MIRT508012 BCAT1 branched chain amino acid transaminase 1 2 4
MIRT510439 ZIC5 Zic family member 5 2 6
MIRT510539 XKR7 XK related 7 2 4
MIRT510600 TPPP tubulin polymerization promoting protein 2 6
MIRT511060 NRAS NRAS proto-oncogene, GTPase 2 4
MIRT511855 GOLGA8J golgin A8 family member J 2 6
MIRT511865 GOLGA8I golgin A8 family member I, pseudogene 1 3
MIRT512570 CTDSPL CTD small phosphatase like 2 2
MIRT512708 ZNF134 zinc finger protein 134 2 6
MIRT513177 MOAP1 modulator of apoptosis 1 2 6
MIRT513783 PAWR pro-apoptotic WT1 regulator 2 6
MIRT515099 IRGQ immunity related GTPase Q 2 2
MIRT515481 INCENP inner centromere protein 2 4
MIRT517416 BMP8A bone morphogenetic protein 8a 2 2
MIRT518754 C1orf35 chromosome 1 open reading frame 35 2 2
MIRT519780 ZNF354B zinc finger protein 354B 2 4
MIRT519865 ZFP62 ZFP62 zinc finger protein 2 6
MIRT520510 TRAM2 translocation associated membrane protein 2 2 6
MIRT521068 SLC25A32 solute carrier family 25 member 32 2 6
MIRT526912 ZNF772 zinc finger protein 772 2 6
MIRT527134 GULP1 GULP, engulfment adaptor PTB domain containing 1 2 2
MIRT527867 SLC39A14 solute carrier family 39 member 14 2 2
MIRT528404 EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2 2
MIRT532956 ZNF24 zinc finger protein 24 2 4
MIRT533021 ZFC3H1 zinc finger C3H1-type containing 2 4
MIRT533191 WASL Wiskott-Aldrich syndrome like 2 6
MIRT534191 SLC7A11 solute carrier family 7 member 11 2 2
MIRT534961 PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2 4
MIRT536396 LCOR ligand dependent nuclear receptor corepressor 2 2
MIRT537046 GRAMD4 GRAM domain containing 4 2 2
MIRT537125 GOLGA3 golgin A3 2 4
MIRT537183 GFPT2 glutamine-fructose-6-phosphate transaminase 2 2 4
MIRT537652 ERGIC2 ERGIC and golgi 2 2 4
MIRT538632 CCSER2 coiled-coil serine rich protein 2 2 4
MIRT539231 ANP32E acidic nuclear phosphoprotein 32 family member E 2 6
MIRT540099 NPY4R neuropeptide Y receptor Y4 2 2
MIRT540998 ZNF460 zinc finger protein 460 2 4
MIRT541468 AURKA aurora kinase A 2 2
MIRT542680 SESN3 sestrin 3 2 2
MIRT542757 PRRG4 proline rich and Gla domain 4 2 2
MIRT542863 NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 2 2
MIRT542925 HOXC8 homeobox C8 2 2
MIRT543747 SZRD1 SUZ RNA binding domain containing 1 2 2
MIRT544404 ZSCAN12 zinc finger and SCAN domain containing 12 2 2
MIRT544583 AP5Z1 adaptor related protein complex 5 zeta 1 subunit 2 4
MIRT544662 MED19 mediator complex subunit 19 2 2
MIRT545251 GTF2E1 general transcription factor IIE subunit 1 2 2
MIRT545261 TRIM36 tripartite motif containing 36 2 4
MIRT545744 UHRF1BP1 UHRF1 binding protein 1 2 2
MIRT545999 WDR81 WD repeat domain 81 2 2
MIRT546038 VPS4B vacuolar protein sorting 4 homolog B 2 2
MIRT547170 PDZD8 PDZ domain containing 8 2 2
MIRT547273 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 2
MIRT547729 KIF5B kinesin family member 5B 2 2
MIRT548127 GATA6 GATA binding protein 6 2 2
MIRT548203 FNIP1 folliculin interacting protein 1 2 2
MIRT548756 CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2 2
MIRT549641 ZNF75A zinc finger protein 75a 2 2
MIRT549684 ZNF598 zinc finger protein 598 2 2
MIRT550197 MRO maestro 2 2
MIRT550340 IPP intracisternal A particle-promoted polypeptide 2 2
MIRT550536 MYZAP myocardial zonula adherens protein 2 2
MIRT550975 TOR4A torsin family 4 member A 2 2
MIRT551221 CIDEC cell death inducing DFFA like effector c 2 2
MIRT551355 AGBL5 ATP/GTP binding protein like 5 2 2
MIRT551571 LETM1 leucine zipper and EF-hand containing transmembrane protein 1 2 2
MIRT552277 RAB3D RAB3D, member RAS oncogene family 2 2
MIRT552661 ZADH2 zinc binding alcohol dehydrogenase domain containing 2 2 2
MIRT553081 UCK2 uridine-cytidine kinase 2 2 2
MIRT553753 TBC1D8 TBC1 domain family member 8 2 2
MIRT554030 SPCS3 signal peptidase complex subunit 3 2 2
MIRT554099 SMU1 DNA replication regulator and spliceosomal factor 2 2
MIRT554155 SLX4 SLX4 structure-specific endonuclease subunit 2 2
MIRT554815 REL REL proto-oncogene, NF-kB subunit 2 2
MIRT555522 PMEPA1 prostate transmembrane protein, androgen induced 1 2 2
MIRT555597 PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma 2 2
MIRT555632 PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 2 4
MIRT555679 PGAM4 phosphoglycerate mutase family member 4 2 4
MIRT555827 PAX9 paired box 9 2 2
MIRT555868 PAIP1 poly(A) binding protein interacting protein 1 2 2
MIRT555939 NUP43 nucleoporin 43 2 2
MIRT555994 NFYB nuclear transcription factor Y subunit beta 2 2
MIRT556340 MAP2K4 mitogen-activated protein kinase kinase 4 2 2
MIRT556432 LONRF3 LON peptidase N-terminal domain and ring finger 3 2 2
MIRT556585 LHFPL2 LHFPL tetraspan subfamily member 2 2 4
MIRT556801 KIAA1958 KIAA1958 2 2
MIRT558047 EXOC5 exocyst complex component 5 2 2
MIRT558697 CLTA clathrin light chain A 2 2
MIRT559191 BMPR1A bone morphogenetic protein receptor type 1A 2 4
MIRT559639 AKAP10 A-kinase anchoring protein 10 2 2
MIRT559707 AEN apoptosis enhancing nuclease 2 2
MIRT560673 SRFBP1 serum response factor binding protein 1 2 2
MIRT560990 GPBP1L1 GC-rich promoter binding protein 1 like 1 2 2
MIRT562170 HOXA13 homeobox A13 2 2
MIRT562275 GNAQ G protein subunit alpha q 2 2
MIRT563624 ZNF277 zinc finger protein 277 2 2
MIRT563815 FMN1 formin 1 2 2
MIRT564096 TLR3 toll like receptor 3 2 2
MIRT565320 TMEM41A transmembrane protein 41A 2 2
MIRT565986 RNF44 ring finger protein 44 2 2
MIRT566047 REV3L REV3 like, DNA directed polymerase zeta catalytic subunit 2 2
MIRT568236 C11orf24 chromosome 11 open reading frame 24 2 2
MIRT568310 BAK1 BCL2 antagonist/killer 1 2 2
MIRT572376 ATOX1 antioxidant 1 copper chaperone 2 2
MIRT574822 CPEB3 cytoplasmic polyadenylation element binding protein 3 2 2
MIRT609212 PELP1 proline, glutamate and leucine rich protein 1 2 2
MIRT616217 RBM27 RNA binding motif protein 27 2 2
MIRT629087 FASLG Fas ligand 2 2
MIRT632124 FKBP9 FK506 binding protein 9 2 2
MIRT632576 POLQ DNA polymerase theta 2 2
MIRT634799 ENTHD1 ENTH domain containing 1 2 2
MIRT636553 ESRP1 epithelial splicing regulatory protein 1 2 2
MIRT640977 ORAI2 ORAI calcium release-activated calcium modulator 2 2 2
MIRT653875 SH2B3 SH2B adaptor protein 3 2 2
MIRT655598 OTUD7B OTU deubiquitinase 7B 2 2
MIRT659764 CCDC171 coiled-coil domain containing 171 2 2
MIRT660744 ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 2 2
MIRT681037 AAED1 AhpC/TSA antioxidant enzyme domain containing 1 2 2
MIRT682305 RBM28 RNA binding motif protein 28 2 2
MIRT682573 EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2 2
MIRT686217 ZNF267 zinc finger protein 267 2 2
MIRT687209 PLXNA3 plexin A3 2 2
MIRT690630 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT692419 AGMAT agmatinase 2 2
MIRT694437 MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2 2
MIRT700725 PNO1 partner of NOB1 homolog 2 2
MIRT701549 NARF nuclear prelamin A recognition factor 2 2
MIRT704379 DAND5 DAN domain BMP antagonist family member 5 2 2
MIRT707935 PPP1R3D protein phosphatase 1 regulatory subunit 3D 2 2
MIRT709939 MRPS16 mitochondrial ribosomal protein S16 2 2
MIRT711371 MED7 mediator complex subunit 7 2 2
MIRT712327 PER2 period circadian clock 2 2 2
MIRT714515 SHE Src homology 2 domain containing E 2 2
MIRT715520 G2E3 G2/M-phase specific E3 ubiquitin protein ligase 2 2
MIRT724294 OSMR oncostatin M receptor 2 2
MIRT725358 MUC21 mucin 21, cell surface associated 2 2
MIRT732242 KLF4 Kruppel like factor 4 3 1
MIRT735384 SPAG5 sperm associated antigen 5 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-367 Medpor NULL NULL Microarray osteoblast-like cells line (MG-63) 18408260 2008 up-regulated
miR-367 Activin A NULL 229455 Quantitative real-time PCR Human embryonic stem (hES) cells 19885849 2010 up-regulated
miR-367 Mistletoe lectin-I NULL NULL Microarray colorectal cancer cells CLY cells 20955366 2011 down-regulated
miR-367 Doxorubicin approved 31703 Quantitative real-time PCR heart 22859947 2012 up-regulated
miR-367 Paclitaxel approved 36314 Microarray Ovarian cancer cell lines 24220856 2014 up-regulated
miR-367 Glucose NULL 5793 Quantitative real-time PCR endothelial cells 24394957 2014 down-regulated
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-367 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Verapamil 2520 NSC272366 approved resistant High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Siop Treatment Protocol sensitive High Nephroblastoma tissue
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved resistant High Pan-Cancer cell line (NCI-H460, NCI-H522, NCI-H322M, HOP62, A549, EKVX, MALME-3M, NCI-H226, HT-29, HCT-116, SE-620, HCT-15, HCC2998, COLO205, HS-578T, NCI/ADR-RES, OVCAR8, OVCAR4, ACHN, SN-12C, 786-O, CAKI-1, UO-31, TK-10, A498, SK-MEL-28, UACC-257, M14, UACC-62, SK
hsa-miR-367-3p Doxorubicin 31703 NSC123127 approved sensitive High Hepatocellular Carcinoma tissue and cell line (HepG2)
hsa-miR-367-3p Mitoxantrone 4212 NSC279836 approved sensitive High Breast Cancer cell line (MCF-7)
hsa-miR-367-3p Sorafenib 216239 NSC747971 approved sensitive Low Hepatocellular Carcinoma cell line (SKhep1, HA22T)
hsa-miR-367-3p Osimertinib 71496458 NSC779217 approved resistant cell line (HCC827)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM16)
hsa-miR-367-3p Vemurafenib 42611257 NSC761431 approved resistant cell line (LM36)
hsa-miR-367-3p Sunitinib 5329102 NSC750690 approved resistant tissue (CardA)
hsa-miR-367-3p Paclitaxel 36314 NSC125973 approved sensitive cell line (SKOV3)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved resistant cell line (IGROV-1)
hsa-miR-367-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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