miRTarBase - #MIRT546543


—
pre-miRNA Information
pre-miRNA hsa-mir-605   
Genomic Coordinates chr10: 51299573 - 51299655
Synonyms MIRN605, hsa-mir-605, MIR605
Description Homo sapiens miR-605 stem-loop
Comment None
RNA Secondary Structure
Associated Diseases

Mature miRNA Information
Mature miRNA hsa-miR-605-3p
Sequence 51| AGAAGGCACUAUGAGAUUUAGA |72
Evidence Experimental
Experiments Illumina
Editing Events in miRNAs
Modification Type Position on miR Chromosome DNA Strand Genomic Position (hg38) List of PMIDs Variant details
A-to-I 4 10 + 51299626 27587585, 28550310, 26028588, 26449202, 26487287, 29165639 MiREDiBase
A-to-I 14 10 + 51299636 29233923 MiREDiBase
A-to-I 20 10 + 51299642 18684997, 26449202, 27587585, 29233923 MiREDiBase
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs759219082 5 dbSNP
rs1491224174 9 dbSNP
rs746611214 10 dbSNP
rs367648737 11 dbSNP
rs1359467239 14 dbSNP
rs1442565019 16 dbSNP
Putative Targets

Gene Information
Gene Symbol SATB2   
Synonyms GLSS
Description SATB homeobox 2
Transcript NM_001172509   
Other Transcripts NM_001172517 , NM_015265   
Expression
Putative miRNA Targets on SATB2
3'UTR of SATB2
(miRNA target sites are highlighted)		 
>SATB2|NM_001172509|3'UTR
   1 TGTGAACTTCTACTAGGCAAAGCAATACATCGGTCCAAGGATTTTCTGCTTTCATTTCTTTAAAAGTTTTTTGTTAGTTT
  81 GTTTTTTGTTTTTGTTTTTGGGTTTTTTTGGCTTTATTTTTGTCTTTTTATGTCTGTTTTGTTTTTCTTACCCTTTTGGA
 161 CATTTCTTTGTTGCACAGGATACACCTATAGACTGAATAAGTTCAGTATTTCCGAATCAGACATCGCCTTGGCAAAGACA
 241 CTAAAGCGTTACACTTTATCCCGTCTCTATGACTGGATCATAGTCATTATAATCACAGGAGACTCTGCCTTCATTATCCT
 321 TGCACTTAACGGAAGTTACATCAGGCAAGTACCAGGATGAAAAGAACTATGAAATAAATGAAGGAAGCTACAAGTGTGTG
 401 TGTATATGTATATGTATATATCTCTATATTTACATATATATATTAAAATTGCATGGGACAGAGACTTTGCAATCCGAAAG
 481 AATAGACTGTGAAATGAGTTCTTAAAGAAAAGACTTGTTTATGTATTAAAAAAACCACTTCACAGTGAGTCGCTTTGGCT
 561 TTTTGATAAACTGCGGCCTGCTCTCAGGGTGGGGTGACTATTTTTGAATTCCTATTTATTTTTTGTGTTTGTCCCTGATT
 641 TTTTTTTTTTAATTCTATGGCTTCCTATCTGGCAGCTTAATGGGTAATTTTTGAGGTATGTATTTAACAAAATAAACGAC
 721 ACTGCCGAAAAAAAAAAAAGTGAAGTGAAAACAATCAGGGCACATTAAAATGATACAAGTCAAATAAATCTTAAAGACAC
 801 AATGCACACTTAAAATGACTCAATAAAATGACTTGCTACGTTCCGTTATTCAATTTGTCATTACTGTAGTGAACAGATGC
 881 ATTTCTGTGGAATTCCAAATAAGTAAAACTGAAATTCAGTGCAGAGAAAACTTTGTCCACTAGTGCAAGTCTTGATCAAA
 961 TGACATTTTGACATTGGACATATGGAATTCATAGTATGAGCCACATTTTGTTGTGAAATTTATTTACCTGCTTGTGGCTT
1041 CAAATCTGAAAATTAATAAGCCTGCTCGTTTAAAAGTTGTTTGTTGTTGCTGTTTTTTTGTCTTTTTGTTTTTTACTAGA
1121 AAATAGTTCAGTGTAATATTAAGTTAGAAAAGAAGTTGCTGCCCAGTTAAAGGGGCTCCCTCTCAAATAAATCTCCATCC
1201 TTCCCTCTCCCAAAAGACATTTCTGATTTCTGCTTCACTTTGGGCTTCCTCTTCTTCGTACACATTCCATCTACCTAATC
1281 AAACATTTTCAGTCCCTGATCTCTCCTGTCCCTTTTCCTGGGATGACAGCCCTAACAAGAACTGTTTTTGAATCGTTGTG
1361 CAGCTCCAGGCAATAGAGTATGTGAAGCGATTTCAGTAGAATCACTTACTCATCCTAAAAGAAAACATTATCCCAGTTAC
1441 CTACATCGCAATTACCTTATGTAAAGCAGAACTAATGCTGACTGGATGTTTAATGGGATGAGCATTAAAGCTGCAATCTA
1521 CTATAGTACTCCAGATCTCTTTCGGCTTCCTATGAGAAACACCAGAAGCATTACTTTCCACTTCTACTTACAGTAATTGC
1601 AAGAGGAGACCTCACATTCAGGACTGGCCTAGTGAACGTAATCCATGCTTTAAACTGGCCATTAAACAGTCCCACATGGT
1681 TGGATTTTTTTTTTTTTTTTGAGTTGTGCTTTCACAAAACCTTGTCAAAGACCTCATGCAATATCACTTTGAAAGTTATT
1761 TTCTGTTTACTACACAAACATTGTAATATAACTGTTAATACTATTTATATATTTGAAAGGTATAAAAGGTAGGAGTTAAA
1841 AAAAAAACCTCTATGTGTAGATATTAACTCAGAACTTACAATATACAGGGAGAAGACATGTTGCAATACAAGCTAATTCT
1921 AGCTGCTCAGTAACCTCTGGAGTTTTTAAAGGGACATTTTCCTGTACTTTTTCAAATAATGATGTTTAAAAATTATCTTG
2001 ACATAAGCGTCATATACCTTTGCAAAAGGATGGTTGTTTGCAGTTAGCCCTGGCCCCATCCTTCCTATTTCTGTAGTATG
2081 CTGCAGCTTTAATCAGAAAGTCCATGGTTGCTGCTTCCTGATCTCCGAGTTACTCTTTCCAAATTGTCTTCTTACACTGT
2161 TGCTGAAGGTCACTCTGTACACGTAATGGAAACTGATTTTGCCAAGCTCTTACAAGGTGGTTCATCTATCGATGGCATCC
2241 GCATTTGGTATCTTTTACACTTCAACCAAAAATTTATTAGGTATTTTTCAATGCTAAGTCTTGCCTTTTATTTTTTAATT
2321 TCACTGCCAAGTTTGCAGTGGTTCTAAGTGAATCTGTGGGCATTTTAGCCTGTGGTCTTGCCAGATCTTTGCGAATTACA
2401 ATGCATATATGTCTATTTATTCAATATCTGTCATATAATATCTATTTGGAAGAAGAAACTTTCTCTTGTAGTGCCTCTTG
2481 ACAAAGCACAATTTCCCGCCTTTTTTTTTTTTTGTGAAATGAAAAAAACAAATTGTGTTTTATTGCGGTATCAACAATGT
2561 GAATAAGGATTAACATATTGTAAATGTTCTTTTTTCCATGTAAATCAACTATCTTTGTTATCACTAAGTGATAATTAATT
2641 TTTAACTTATGTGCATTGTTAGGCTGTTAGAATTTTTTGGTTGTTAAAATAAACGCATTCAATAAATATGA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' agAU-UUAGAGU-AUC----ACGGAAGa 5'
            || |||| ||  ||    ||||||| 
Target 5' atTATAATCACAGGAGACTCTGCCTTCa 3'
 286 - 313 154.00 -10.80
2 
miRNA  3' agAUUUAGA---GUAUCACGGAAGa 5'
            | | |||   || | ||:|||| 
Target 5' agTTACTCTTTCCAAATTGTCTTCt 3'
 2128 - 2152 140.00 -9.80
3 
miRNA  3' agAUUUAGAGUAUCACGGAAGa 5'
            |||:|||     ||||||: 
Target 5' gcTAAGTCT-----TGCCTTTt 3'
 2293 - 2309 139.00 -15.50
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN20052769 13 COSMIC
COSN30508532 15 COSMIC
COSN31598570 24 COSMIC
COSN30472199 31 COSMIC
COSN30147464 53 COSMIC
COSN30498559 56 COSMIC
COSN16496601 63 COSMIC
COSN510549 65 COSMIC
COSN31512461 88 COSMIC
COSN31522107 99 COSMIC
COSN30498502 102 COSMIC
COSN1818300 208 COSMIC
COSN8277243 247 COSMIC
COSN28882435 248 COSMIC
COSN20983968 475 COSMIC
COSN31608836 507 COSMIC
COSN31548971 512 COSMIC
COSN29712629 578 COSMIC
COSN32069336 592 COSMIC
COSN26506044 618 COSMIC
COSN20097644 639 COSMIC
COSN31486399 693 COSMIC
COSN16760249 712 COSMIC
COSN31608835 718 COSMIC
COSN19657911 727 COSMIC
COSN27314176 727 COSMIC
COSN5865245 789 COSMIC
COSN31550169 800 COSMIC
COSN20090699 817 COSMIC
COSN5494377 853 COSMIC
COSN15735175 863 COSMIC
COSN31531170 867 COSMIC
COSN31553698 1004 COSMIC
COSN28687316 1090 COSMIC
COSN6931958 1284 COSMIC
COSN23183160 1420 COSMIC
COSN25852890 1443 COSMIC
COSN20097639 1684 COSMIC
COSN20097643 1685 COSMIC
COSN5857427 1838 COSMIC
COSN8608332 2009 COSMIC
COSN8764718 2040 COSMIC
COSN8608331 2064 COSMIC
COSN28831309 2091 COSMIC
COSN31514767 2140 COSMIC
COSN31584362 2152 COSMIC
COSN17236784 2182 COSMIC
COSN14587576 2203 COSMIC
COSN31568382 2241 COSMIC
COSN9303395 2298 COSMIC
COSN6163772 2328 COSMIC
COSN27501800 2393 COSMIC
COSN17806512 2435 COSMIC
COSN19323128 2500 COSMIC
COSN20097633 2500 COSMIC
COSN26575407 2525 COSMIC
COSN31542598 2525 COSMIC
COSN26573530 2537 COSMIC
COSN31961767 2596 COSMIC
COSN1818299 2608 COSMIC
COSN19149664 2631 COSMIC
COSN28757647 2647 COSMIC
COSN31585393 2674 COSMIC
COSN16798313 2695 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1291830270 2 dbSNP
rs748489700 10 dbSNP
rs748217198 12 dbSNP
rs767911756 22 dbSNP
rs1209129769 24 dbSNP
rs1338706001 26 dbSNP
rs1268447041 29 dbSNP
rs779055301 31 dbSNP
rs755168487 32 dbSNP
rs1302775719 37 dbSNP
rs995338777 40 dbSNP
rs527928674 43 dbSNP
rs1237115297 51 dbSNP
rs897213025 54 dbSNP
rs1037121896 64 dbSNP
rs1355109488 66 dbSNP
rs1188962760 77 dbSNP
rs560563531 77 dbSNP
rs530875805 83 dbSNP
rs1368509469 85 dbSNP
rs187998908 87 dbSNP
rs1164818808 88 dbSNP
rs985027549 88 dbSNP
rs182271081 90 dbSNP
rs1467452757 93 dbSNP
rs1332480200 100 dbSNP
rs1345298259 102 dbSNP
rs367631315 103 dbSNP
rs1026607372 110 dbSNP
rs1389925418 110 dbSNP
rs201827002 141 dbSNP
rs1307295402 145 dbSNP
rs1050219682 152 dbSNP
rs147496717 163 dbSNP
rs1356036761 167 dbSNP
rs932874088 170 dbSNP
rs556296849 176 dbSNP
rs1257213142 178 dbSNP
rs544464325 185 dbSNP
rs577064187 189 dbSNP
rs1201796159 192 dbSNP
rs1256494035 196 dbSNP
rs1441333823 197 dbSNP
rs867699679 200 dbSNP
rs769837198 205 dbSNP
rs770984154 206 dbSNP
rs893104044 213 dbSNP
rs759359447 214 dbSNP
rs1442405138 216 dbSNP
rs956198412 223 dbSNP
rs1479103754 225 dbSNP
rs1171789034 226 dbSNP
rs1372831279 241 dbSNP
rs1460829650 246 dbSNP
rs923645087 248 dbSNP
rs1475550131 252 dbSNP
rs1403259761 253 dbSNP
rs1414172459 262 dbSNP
rs977885540 263 dbSNP
rs12993660 275 dbSNP
rs1400571144 279 dbSNP
rs1384284538 280 dbSNP
rs776590051 286 dbSNP
rs768498169 287 dbSNP
rs1277543777 295 dbSNP
rs1305539466 297 dbSNP
rs1180611101 304 dbSNP
rs1481852961 313 dbSNP
rs1235230444 320 dbSNP
rs1256156559 324 dbSNP
rs959280358 331 dbSNP
rs1026866985 335 dbSNP
rs995261866 337 dbSNP
rs1208041850 347 dbSNP
rs6435006 351 dbSNP
rs949844723 356 dbSNP
rs1037497108 360 dbSNP
rs894329615 361 dbSNP
rs77468147 369 dbSNP
rs1055526749 379 dbSNP
rs1204864297 382 dbSNP
rs1425374958 390 dbSNP
rs941099884 391 dbSNP
rs1450697829 396 dbSNP
rs551588093 400 dbSNP
rs891230761 402 dbSNP
rs1362505288 411 dbSNP
rs1420447819 420 dbSNP
rs1288215133 426 dbSNP
rs772055529 437 dbSNP
rs1049751107 441 dbSNP
rs1047168993 444 dbSNP
rs929693092 470 dbSNP
rs932676187 475 dbSNP
rs1330112594 476 dbSNP
rs1231592101 477 dbSNP
rs745498887 494 dbSNP
rs976328391 503 dbSNP
rs1215340422 514 dbSNP
rs1260579680 517 dbSNP
rs1287697947 521 dbSNP
rs1193234920 525 dbSNP
rs1054713608 528 dbSNP
rs1454139211 529 dbSNP
rs910728368 530 dbSNP
rs778715719 533 dbSNP
rs1343316221 535 dbSNP
rs957447534 535 dbSNP
rs1294087873 536 dbSNP
rs1393434747 551 dbSNP
rs1033130436 569 dbSNP
rs1310989639 574 dbSNP
rs924815961 575 dbSNP
rs967426810 580 dbSNP
rs1024617275 585 dbSNP
rs982044703 591 dbSNP
rs1328128091 600 dbSNP
rs190042308 603 dbSNP
rs894282114 612 dbSNP
rs186107760 615 dbSNP
rs949144340 619 dbSNP
rs1055640386 622 dbSNP
rs1462074131 629 dbSNP
rs114405014 631 dbSNP
rs1405850812 636 dbSNP
rs79165231 638 dbSNP
rs78418954 639 dbSNP
rs1425689889 641 dbSNP
rs535960709 642 dbSNP
rs888186447 649 dbSNP
rs1417157270 650 dbSNP
rs1204502231 651 dbSNP
rs1400508837 651 dbSNP
rs35758003 651 dbSNP
rs397987299 651 dbSNP
rs1441065916 652 dbSNP
rs1296133513 653 dbSNP
rs1046840493 657 dbSNP
rs1228462905 667 dbSNP
rs559471414 673 dbSNP
rs1294373591 679 dbSNP
rs1334783427 681 dbSNP
rs1231793592 682 dbSNP
rs1260432194 695 dbSNP
rs1421395197 708 dbSNP
rs1204062897 712 dbSNP
rs1409273491 713 dbSNP
rs929613421 717 dbSNP
rs1191002629 718 dbSNP
rs1477221221 719 dbSNP
rs1250795765 720 dbSNP
rs1256650428 721 dbSNP
rs1215148933 722 dbSNP
rs753313213 725 dbSNP
rs1266928906 726 dbSNP
rs1212949390 727 dbSNP
rs775655256 728 dbSNP
rs1040569490 738 dbSNP
rs1355335621 740 dbSNP
rs1486130993 740 dbSNP
rs60420320 740 dbSNP
rs944961989 740 dbSNP
rs1318673201 741 dbSNP
rs1307564029 746 dbSNP
rs1271071142 752 dbSNP
rs1218464528 753 dbSNP
rs1211631515 757 dbSNP
rs910842929 762 dbSNP
rs568807856 772 dbSNP
rs181138294 774 dbSNP
rs1474921641 779 dbSNP
rs1184573999 785 dbSNP
rs1441900619 790 dbSNP
rs150702506 801 dbSNP
rs1026835905 802 dbSNP
rs973974701 803 dbSNP
rs1421049403 807 dbSNP
rs761048331 811 dbSNP
rs1327538536 838 dbSNP
rs957588292 839 dbSNP
rs961620761 840 dbSNP
rs1413167883 844 dbSNP
rs1235261648 845 dbSNP
rs35679091 845 dbSNP
rs531993363 857 dbSNP
rs1008519354 858 dbSNP
rs977548653 866 dbSNP
rs1455554204 867 dbSNP
rs1213334986 881 dbSNP
rs1248208502 903 dbSNP
rs756549653 919 dbSNP
rs753271408 921 dbSNP
rs1028416360 928 dbSNP
rs1192600915 934 dbSNP
rs1392948476 935 dbSNP
rs996808784 939 dbSNP
rs893158788 940 dbSNP
rs571047738 945 dbSNP
rs1054683030 950 dbSNP
rs552950459 954 dbSNP
rs1014143076 970 dbSNP
rs1400672610 973 dbSNP
rs1316893610 975 dbSNP
rs934885375 979 dbSNP
rs1034303676 980 dbSNP
rs527863202 983 dbSNP
rs879640661 983 dbSNP
rs552009799 989 dbSNP
rs1247224542 1001 dbSNP
rs1282198182 1006 dbSNP
rs560701010 1021 dbSNP
rs1341742329 1027 dbSNP
rs1242345055 1028 dbSNP
rs1293646132 1041 dbSNP
rs1280240596 1056 dbSNP
rs950297763 1061 dbSNP
rs1221980330 1064 dbSNP
rs1047229008 1065 dbSNP
rs917635465 1066 dbSNP
rs151132928 1067 dbSNP
rs770685016 1067 dbSNP
rs573354220 1068 dbSNP
rs1181857247 1070 dbSNP
rs942403805 1076 dbSNP
rs561392243 1086 dbSNP
rs1157326897 1089 dbSNP
rs768866470 1100 dbSNP
rs1446456909 1102 dbSNP
rs530156172 1103 dbSNP
rs1174670198 1108 dbSNP
rs1325677658 1108 dbSNP
rs1392503152 1111 dbSNP
rs1429462511 1115 dbSNP
rs1329849329 1118 dbSNP
rs1335231108 1119 dbSNP
rs191483869 1124 dbSNP
rs1285809612 1130 dbSNP
rs1335411376 1146 dbSNP
rs919582376 1147 dbSNP
rs544287696 1152 dbSNP
rs749455277 1155 dbSNP
rs1232404869 1161 dbSNP
rs973734331 1165 dbSNP
rs1271073918 1166 dbSNP
rs751713026 1178 dbSNP
rs1195998648 1183 dbSNP
rs766538501 1195 dbSNP
rs1295226987 1203 dbSNP
rs1389202662 1204 dbSNP
rs763039605 1205 dbSNP
rs1260166934 1209 dbSNP
rs936141777 1209 dbSNP
rs1164880487 1212 dbSNP
rs961317349 1216 dbSNP
rs1416114350 1224 dbSNP
rs1015963454 1227 dbSNP
rs1167843964 1228 dbSNP
rs11543297 1233 dbSNP
rs926153931 1244 dbSNP
rs543003438 1245 dbSNP
rs1396040830 1248 dbSNP
rs977876693 1254 dbSNP
rs946158383 1255 dbSNP
rs1261803521 1257 dbSNP
rs114242071 1258 dbSNP
rs1484654685 1262 dbSNP
rs1227973398 1264 dbSNP
rs773142517 1270 dbSNP
rs1201630487 1281 dbSNP
rs955384707 1291 dbSNP
rs1028386674 1305 dbSNP
rs1341153593 1308 dbSNP
rs1249878565 1317 dbSNP
rs1256100555 1320 dbSNP
rs1430595144 1323 dbSNP
rs1229861394 1324 dbSNP
rs1372674550 1329 dbSNP
rs996945649 1336 dbSNP
rs867019611 1354 dbSNP
rs1231466887 1355 dbSNP
rs1434251114 1358 dbSNP
rs1310992101 1360 dbSNP
rs1387055103 1372 dbSNP
rs186637999 1374 dbSNP
rs376628235 1378 dbSNP
rs984073804 1380 dbSNP
rs1324508303 1382 dbSNP
rs1234930862 1384 dbSNP
rs373463379 1388 dbSNP
rs952625600 1389 dbSNP
rs576361770 1405 dbSNP
rs1278736842 1406 dbSNP
rs999300965 1412 dbSNP
rs1206051136 1413 dbSNP
rs1261437404 1416 dbSNP
rs1427163013 1418 dbSNP
rs1394757203 1429 dbSNP
rs1195721129 1432 dbSNP
rs1296151685 1439 dbSNP
rs903427463 1444 dbSNP
rs376661560 1447 dbSNP
rs760681219 1448 dbSNP
rs554367955 1451 dbSNP
rs1346845094 1455 dbSNP
rs900911975 1466 dbSNP
rs535897547 1477 dbSNP
rs1288266146 1494 dbSNP
rs1373224122 1495 dbSNP
rs1382489986 1500 dbSNP
rs775624317 1502 dbSNP
rs771931204 1510 dbSNP
rs1055918298 1511 dbSNP
rs937745689 1512 dbSNP
rs1231369906 1516 dbSNP
rs1310859474 1517 dbSNP
rs889467021 1520 dbSNP
rs919718179 1521 dbSNP
rs568869625 1523 dbSNP
rs1037995632 1533 dbSNP
rs1468222671 1534 dbSNP
rs1482637499 1543 dbSNP
rs1248144672 1544 dbSNP
rs904652066 1546 dbSNP
rs1158281755 1550 dbSNP
rs1361995020 1551 dbSNP
rs181632768 1552 dbSNP
rs1393221181 1558 dbSNP
rs1383269106 1563 dbSNP
rs1438225619 1568 dbSNP
rs1299581975 1574 dbSNP
rs1041889208 1580 dbSNP
rs946243090 1587 dbSNP
rs1306833738 1590 dbSNP
rs557060067 1591 dbSNP
rs1235472195 1598 dbSNP
rs1274233374 1599 dbSNP
rs1334666955 1610 dbSNP
rs939692583 1612 dbSNP
rs140878661 1615 dbSNP
rs1480961983 1616 dbSNP
rs1176701162 1619 dbSNP
rs987138703 1624 dbSNP
rs571248300 1629 dbSNP
rs1165608315 1637 dbSNP
rs552889002 1638 dbSNP
rs900472811 1644 dbSNP
rs1459734206 1658 dbSNP
rs1172087791 1661 dbSNP
rs1354758423 1671 dbSNP
rs937302804 1673 dbSNP
rs1295968813 1676 dbSNP
rs199614602 1684 dbSNP
rs1337004338 1689 dbSNP
rs528005778 1694 dbSNP
rs111851136 1701 dbSNP
rs1275305939 1701 dbSNP
rs397987298 1701 dbSNP
rs67882050 1701 dbSNP
rs879216848 1701 dbSNP
rs1294492638 1702 dbSNP
rs1228304901 1704 dbSNP
rs1334431782 1706 dbSNP
rs984405005 1707 dbSNP
rs1309613965 1708 dbSNP
rs1272530414 1713 dbSNP
rs1486724587 1715 dbSNP
rs1188554806 1722 dbSNP
rs1256810168 1724 dbSNP
rs921084055 1731 dbSNP
rs1396798490 1739 dbSNP
rs1419730804 1745 dbSNP
rs1427591046 1747 dbSNP
rs1324764127 1751 dbSNP
rs567040204 1768 dbSNP
rs975266319 1780 dbSNP
rs1026015302 1784 dbSNP
rs1434868830 1796 dbSNP
rs1396013336 1797 dbSNP
rs1240202131 1804 dbSNP
rs1375386487 1807 dbSNP
rs1446205098 1810 dbSNP
rs1272316559 1820 dbSNP
rs1363138487 1822 dbSNP
rs1165644168 1833 dbSNP
rs1469567322 1834 dbSNP
rs1361934940 1838 dbSNP
rs972578987 1847 dbSNP
rs201780110 1848 dbSNP
rs540094936 1848 dbSNP
rs571902577 1848 dbSNP
rs957438759 1852 dbSNP
rs1033128109 1853 dbSNP
rs1217633203 1854 dbSNP
rs572564794 1855 dbSNP
rs998832513 1855 dbSNP
rs1184398852 1858 dbSNP
rs1266992590 1861 dbSNP
rs1396511628 1868 dbSNP
rs1191963610 1871 dbSNP
rs1172497108 1872 dbSNP
rs1469925332 1873 dbSNP
rs1413231761 1878 dbSNP
rs1320907396 1879 dbSNP
rs1346148067 1886 dbSNP
rs967801828 1889 dbSNP
rs548801095 1899 dbSNP
rs1208115587 1900 dbSNP
rs1014908585 1904 dbSNP
rs904767297 1917 dbSNP
rs1042392615 1922 dbSNP
rs189267925 1927 dbSNP
rs1240250915 1929 dbSNP
rs1330860234 1930 dbSNP
rs1446143415 1930 dbSNP
rs1206605625 1934 dbSNP
rs1254437355 1935 dbSNP
rs1468665878 1945 dbSNP
rs1302306625 1953 dbSNP
rs1192657407 1954 dbSNP
rs896006201 1964 dbSNP
rs749010264 1970 dbSNP
rs184841500 1982 dbSNP
rs1048382427 2000 dbSNP
rs180823463 2000 dbSNP
rs551083526 2003 dbSNP
rs1399561560 2004 dbSNP
rs918491420 2007 dbSNP
rs755710243 2008 dbSNP
rs748597807 2009 dbSNP
rs939677352 2012 dbSNP
rs1160196289 2015 dbSNP
rs965154785 2016 dbSNP
rs535958431 2026 dbSNP
rs1454164660 2030 dbSNP
rs781666378 2032 dbSNP
rs1264913555 2040 dbSNP
rs1394237621 2042 dbSNP
rs1192061062 2049 dbSNP
rs1181926357 2058 dbSNP
rs908216745 2072 dbSNP
rs1050809766 2079 dbSNP
rs1472569598 2094 dbSNP
rs755293542 2127 dbSNP
rs1032543750 2132 dbSNP
rs1455753377 2133 dbSNP
rs1164397520 2134 dbSNP
rs1000525352 2135 dbSNP
rs568567141 2143 dbSNP
rs1329657536 2146 dbSNP
rs747623111 2155 dbSNP
rs966804383 2155 dbSNP
rs921219938 2157 dbSNP
rs1188034501 2160 dbSNP
rs1445316290 2165 dbSNP
rs1295113232 2175 dbSNP
rs187962002 2177 dbSNP
rs957200203 2182 dbSNP
rs1206221648 2183 dbSNP
rs925988207 2194 dbSNP
rs775937630 2195 dbSNP
rs1341071583 2200 dbSNP
rs895953755 2204 dbSNP
rs1197150920 2205 dbSNP
rs1481816181 2215 dbSNP
rs1203616153 2216 dbSNP
rs1260232643 2218 dbSNP
rs1475705820 2228 dbSNP
rs1278633300 2237 dbSNP
rs967518498 2240 dbSNP
rs1024709936 2241 dbSNP
rs1014297861 2250 dbSNP
rs1168759828 2255 dbSNP
rs1370011065 2258 dbSNP
rs1427977229 2265 dbSNP
rs1001736886 2266 dbSNP
rs1376010109 2267 dbSNP
rs1413892308 2283 dbSNP
rs866229753 2289 dbSNP
rs1310356584 2305 dbSNP
rs1328022557 2328 dbSNP
rs184512660 2330 dbSNP
rs1034571261 2335 dbSNP
rs540111472 2339 dbSNP
rs1269291773 2344 dbSNP
rs1339444442 2346 dbSNP
rs1303636198 2350 dbSNP
rs1212418075 2354 dbSNP
rs750848804 2359 dbSNP
rs1283027940 2378 dbSNP
rs994924279 2386 dbSNP
rs572805680 2392 dbSNP
rs899360570 2393 dbSNP
rs1320277926 2400 dbSNP
rs1194159058 2408 dbSNP
rs1389785570 2411 dbSNP
rs1382706971 2415 dbSNP
rs1374705413 2416 dbSNP
rs1016658127 2424 dbSNP
rs1004359134 2429 dbSNP
rs931304273 2432 dbSNP
rs781570019 2433 dbSNP
rs1436306337 2435 dbSNP
rs1395956046 2436 dbSNP
rs1301067510 2438 dbSNP
rs1386856402 2444 dbSNP
rs1382639714 2452 dbSNP
rs1319398756 2459 dbSNP
rs757553245 2462 dbSNP
rs1167528362 2463 dbSNP
rs192571654 2496 dbSNP
rs1474499336 2497 dbSNP
rs1040468512 2498 dbSNP
rs1193901871 2499 dbSNP
rs1175836890 2500 dbSNP
rs1254827124 2501 dbSNP
rs58333872 2501 dbSNP
rs1255964436 2511 dbSNP
rs1213505499 2512 dbSNP
rs386392268 2513 dbSNP
rs1463740978 2514 dbSNP
rs201400095 2514 dbSNP
rs367546534 2514 dbSNP
rs386392269 2514 dbSNP
rs1158186101 2516 dbSNP
rs374777812 2516 dbSNP
rs1491487747 2517 dbSNP
rs1491533526 2518 dbSNP
rs1280661959 2521 dbSNP
rs1213615897 2522 dbSNP
rs918594785 2524 dbSNP
rs1384569352 2529 dbSNP
rs892001275 2529 dbSNP
rs1271437634 2533 dbSNP
rs1227453102 2537 dbSNP
rs1053207983 2542 dbSNP
rs1036914097 2546 dbSNP
rs1310955008 2547 dbSNP
rs1267864821 2558 dbSNP
rs1327592713 2563 dbSNP
rs1215775396 2574 dbSNP
rs886887857 2582 dbSNP
rs1416436157 2583 dbSNP
rs1375821924 2584 dbSNP
rs943958558 2590 dbSNP
rs1252526003 2596 dbSNP
rs1051200172 2608 dbSNP
rs912520503 2615 dbSNP
rs933679221 2617 dbSNP
rs112378472 2623 dbSNP
rs751228058 2631 dbSNP
rs750719581 2650 dbSNP
rs1462877045 2661 dbSNP
rs1421841275 2670 dbSNP
rs765215959 2675 dbSNP
rs1168590697 2687 dbSNP
rs1348954957 2694 dbSNP
rs985254252 2694 dbSNP
rs188339130 2695 dbSNP
rs1416385081 2700 dbSNP
rs1410956834 2702 dbSNP
rs1288334121 2706 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23314.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714645. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000417098.1 | 3UTR | ACUCUGCCUUCAUUAUCCUUGCACUUAACG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714645
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repB
Location of target site ENST00000417098.1 | 3UTR | CCUUCAUUAUCCUUGCACUUAACG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
100 hsa-miR-605-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT061339 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT061584 BTG2 BTG anti-proliferation factor 2 2 6
MIRT076140 WDR81 WD repeat domain 81 2 2
MIRT079361 CCDC137 coiled-coil domain containing 137 2 2
MIRT079547 VAMP3 vesicle associated membrane protein 3 2 2
MIRT096242 CANX calnexin 2 2
MIRT243877 G3BP1 G3BP stress granule assembly factor 1 2 4
MIRT249186 AKIRIN1 akirin 1 2 8
MIRT273604 SP1 Sp1 transcription factor 2 2
MIRT316766 FOXC1 forkhead box C1 2 4
MIRT322410 PPP2R2A protein phosphatase 2 regulatory subunit Balpha 2 2
MIRT370117 TRIB3 tribbles pseudokinase 3 2 2
MIRT392725 UBN2 ubinuclein 2 2 2
MIRT406910 PTBP1 polypyrimidine tract binding protein 1 2 2
MIRT407440 CTDSP1 CTD small phosphatase 1 2 2
MIRT441887 RD3 retinal degeneration 3 2 4
MIRT444979 C15orf52 chromosome 15 open reading frame 52 2 2
MIRT445241 FOXD4 forkhead box D4 2 2
MIRT445500 FOXD4L5 forkhead box D4 like 5 2 2
MIRT445503 FOXD4L4 forkhead box D4 like 4 2 2
MIRT447025 FOXD4L1 forkhead box D4 like 1 2 2
MIRT447743 TMCC3 transmembrane and coiled-coil domain family 3 2 2
MIRT448761 HDX highly divergent homeobox 2 2
MIRT450003 HAX1 HCLS1 associated protein X-1 2 2
MIRT452830 FAM131B family with sequence similarity 131 member B 2 2
MIRT452872 LAX1 lymphocyte transmembrane adaptor 1 2 2
MIRT453506 ARRB1 arrestin beta 1 2 2
MIRT454169 HIST1H2BK histone cluster 1 H2B family member k 2 2
MIRT458742 CES2 carboxylesterase 2 2 2
MIRT459166 HSPA6 heat shock protein family A (Hsp70) member 6 2 21
MIRT460246 IL17RB interleukin 17 receptor B 2 4
MIRT460514 SDE2 SDE2 telomere maintenance homolog 2 2
MIRT460698 RNF157 ring finger protein 157 2 2
MIRT461481 METTL1 methyltransferase like 1 2 2
MIRT462617 C20orf27 chromosome 20 open reading frame 27 2 4
MIRT463233 ZNF131 zinc finger protein 131 2 2
MIRT465699 TNPO2 transportin 2 2 8
MIRT466304 TIMM22 translocase of inner mitochondrial membrane 22 2 2
MIRT468957 RPS14 ribosomal protein S14 2 6
MIRT469571 RARA retinoic acid receptor alpha 2 2
MIRT469685 RAB5B RAB5B, member RAS oncogene family 2 2
MIRT470800 PMP22 peripheral myelin protein 22 2 2
MIRT471649 PANK2 pantothenate kinase 2 2 4
MIRT471722 OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2 2
MIRT472281 NFIB nuclear factor I B 2 4
MIRT473680 MAPKBP1 mitogen-activated protein kinase binding protein 1 2 2
MIRT475859 H6PD hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase 2 2
MIRT477326 EPHA2 EPH receptor A2 2 2
MIRT477831 DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 2 2
MIRT478572 CTNND1 catenin delta 1 2 4
MIRT479634 CD81 CD81 molecule 2 2
MIRT481950 ANKRD11 ankyrin repeat domain 11 2 2
MIRT483696 ZNF74 zinc finger protein 74 2 6
MIRT488798 MALT1 MALT1 paracaspase 2 2
MIRT489066 STARD3 StAR related lipid transfer domain containing 3 2 2
MIRT492533 PSMD11 proteasome 26S subunit, non-ATPase 11 2 2
MIRT492857 NRARP NOTCH regulated ankyrin repeat protein 2 2
MIRT496793 BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 2 2
MIRT500122 ZNF106 zinc finger protein 106 2 4
MIRT505359 TMEM167A transmembrane protein 167A 2 2
MIRT506786 KLHL15 kelch like family member 15 2 6
MIRT510692 SRM spermidine synthase 2 6
MIRT515841 CEP104 centrosomal protein 104 2 4
MIRT516448 ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 2 4
MIRT528855 PKP1 plakophilin 1 2 2
MIRT533848 TET3 tet methylcytosine dioxygenase 3 2 2
MIRT539025 ATXN7L1 ataxin 7 like 1 2 4
MIRT542872 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT546543 SATB2 SATB homeobox 2 2 2
MIRT554114 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 2 2
MIRT560569 ZNF460 zinc finger protein 460 2 2
MIRT560796 EPM2AIP1 EPM2A interacting protein 1 2 2
MIRT562836 GCFC2 GC-rich sequence DNA-binding factor 2 2 2
MIRT563109 IFRD2 interferon related developmental regulator 2 2 2
MIRT564177 MRPL49 mitochondrial ribosomal protein L49 2 2
MIRT564283 ASB1 ankyrin repeat and SOCS box containing 1 2 2
MIRT564350 USP22 ubiquitin specific peptidase 22 2 2
MIRT565279 TNFRSF21 TNF receptor superfamily member 21 2 2
MIRT565338 TMEM104 transmembrane protein 104 2 2
MIRT565905 SCAMP2 secretory carrier membrane protein 2 2 2
MIRT567108 ITGB1 integrin subunit beta 1 2 2
MIRT567601 FANCF Fanconi anemia complementation group F 2 2
MIRT567779 DGAT2 diacylglycerol O-acyltransferase 2 2 2
MIRT568075 CENPQ centromere protein Q 2 2
MIRT624304 COL12A1 collagen type XII alpha 1 chain 2 2
MIRT644395 CDKL1 cyclin dependent kinase like 1 2 2
MIRT661547 ZNF674 zinc finger protein 674 2 4
MIRT670949 IRAK3 interleukin 1 receptor associated kinase 3 2 2
MIRT672951 AKAP5 A-kinase anchoring protein 5 2 2
MIRT697426 ZFP36 ZFP36 ring finger protein 2 2
MIRT700793 PIAS2 protein inhibitor of activated STAT 2 2 2
MIRT702657 ITGA3 integrin subunit alpha 3 2 2
MIRT708945 FZR1 fizzy and cell division cycle 20 related 1 2 2
MIRT713657 PLCE1 phospholipase C epsilon 1 2 2
MIRT719239 CYSLTR2 cysteinyl leukotriene receptor 2 2 2
MIRT719951 BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 2 2
MIRT722048 HLA-E major histocompatibility complex, class I, E 2 2
MIRT722201 URM1 ubiquitin related modifier 1 2 2
MIRT724790 C1D C1D nuclear receptor corepressor 2 2
MIRT734347 CYP2B6 cytochrome P450 family 2 subfamily B member 6 3 0
miRNA-Drug Associations
miRNA Small Melocule FDA CID Detection Method Condition PMID Year Expression Pattern of miRNA
miR-605 Anthranilamide-pyrazolo[1,5-a]pyrimidine NULL NULL Quantitative real-time PCR neuroblastoma cells 23992861 2013 up-regualted
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)
hsa-mir-605 Paclitaxel 36314 NSC125973 approved sensitive cell line (A2780)
hsa-mir-605 Cisplatin 5460033 NSC119875 approved sensitive cell line (A2780)
hsa-mir-605 Ceritinib 57379345 NSC776422 approved resistant cell line (H3122)
hsa-miR-605-3p Ceritinib 57379345 NSC776422 approved resistant High Non-Small Cell Lung Cancer cell line (H3122, H2228)

Error report submission