pre-miRNA Information
pre-miRNA hsa-mir-4524a   
Genomic Coordinates chr17: 69099564 - 69099632
Description Homo sapiens miR-4524a stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-4524a-5p
Sequence 6| AUAGCAGCAUGAACCUGUCUCA |27
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1322445998 8 dbSNP
rs1350790266 13 dbSNP
rs1263495678 21 dbSNP
Putative Targets

Gene Information
Gene Symbol RNF149   
Synonyms DNAPTP2
Description ring finger protein 149
Transcript NM_173647   
Expression
Putative miRNA Targets on RNF149
3'UTR of RNF149
(miRNA target sites are highlighted)
>RNF149|NM_173647|3'UTR
   1 CACACGTGCCCACTGAAGTGGCACCAACAGAAGTTTGGCTTGAACTAAAGGACATTTTATTTTTTTTACTTTAGCACATA
  81 ATTTGTATATTTGAAAATAATGTATATTATTTTACCTATTAGATTCTGATTTGATATACAAAGGACTAAGATATTTTCTT
 161 CTTGAAGAGACTTTTCGATTAGTCCTCATATATTTATCTACTAAAATAGAGTGTTTACCATGAACAGTGTGTTGCTTCAG
 241 ACTATTACAAAGACAACTGGGGCAGGTACTCTAATATAAAGGACAGGTGGTGTTTCTAAATAATTGGCTGCTATGGTTCT
 321 GTAAAAACCAGTTAATTCTATTTTTCAAGGTTTTTGGCAAAGCACATCAATGTTAGACTAGTTGAAGTGGAATTGTATAA
 401 TTCAATTCGATAATTGATCTCATGGGCTTTCCCTGGAGGAAAGGTTTTTTTTGTTGTTTTTTTTTTAAGAACTTGAAACT
 481 TGTAAACTGAGATGTCTGTAGCTTTTTTGCCCATCTGTAGTGTATGTGAAGATTTCAAAACCTGAGAGCACTTTTTCTTT
 561 GTTTAGAATTATGAGAAAGGCACTAGATGACTTTAGGATTTGCATTTTTCCCTTTATTGCCTCATTTCTTGTGACGCCTT
 641 GTTGGGGAGGGAAATCTGTTTATTTTTTCCTACAAATAAAAAGCTAAGATTCTATATCGCACATGAGCATTAAGTTCTTC
 721 ATTGCCTTGTTAAGGAAAATGAGTAGGCAGACTCAGAATCTGTTATATTGATTTCAGTTACAATTTAATCTTTACAATTA
 801 AAAGGGCGAAAGATGTAGAATTTTAGTTTTTGTTGTTGACTCGAAATAACCAGTTTTCTTGATTAGAGTTTAAGCAGATT
 881 TAATACCATGACCTTGCTTAACCGTTTCTTCTTTTTTACTTGCTTGCTGTTCTTTTGGGTCAAAGGAGCAGGCTAATGCA
 961 AAGCTTTTGGAGACTGCTAAGTGTTAAAAAGTGATTAAACACACACTCTGCTATTTTTTCACTTCTTGGAGGTAGAAGTC
1041 GAGTATGAGGCAGTTATTTTTTAGAGTGTGGAATTATAGTCTTTCCTTGCTCCTAGTTATTCTGTATATCTTTACTTTGT
1121 AGGTAAAAATAAATGTTTATTTAAAACAATTTTTAAAATTATAAATTTATTTTTATAGCCATATGTAGGATATAAAGATT
1201 TATATAGATTATTTTCTCAAGCTACTTAATGCTTTAATTCTAGCTACTCATCATGAAATAGTAAACAGTTTTACTGAAAT
1281 AAACTCTACAGACAGATGCAGTATGAGGAGCTATTGAAGTAGAAAATGTATTTCGCTTTGCACACTGAGTTGGTTTTAGC
1361 AGACAACCTCAAGTAGGTTTCCATAACAGCCATTACCTTTGAAATCTACCTTCTGTAGTTTATTATAAATAGGAAAATAC
1441 ATCCTGATTCTGTAGCAAGTAGATTGTTTGCTCTTTGTCTTTAAGAAATACTAGGAGGGCCGGGCGCGGTGGCTCACGCC
1521 TGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCCGGCTAAAACGGTGA
1601 AACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGG
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' acUCUGUCC------AAG------UA--CGACGAUa 5'
            :||||||      |||      ||  ||||||| 
Target 5' aaGGACAGGTGGTGTTTCTAAATAATTGGCTGCTAt 3'
279 - 314 150.00 -20.80
2
miRNA  3' acucuguccaaguacGACGAUa 5'
                         |||||| 
Target 5' caaagcttttggagaCTGCTAa 3'
959 - 980 120.00 -7.60
3
miRNA  3' acucuguccaaguacGACGAUa 5'
                         |||||| 
Target 5' gattaaacacacactCTGCTAt 3'
993 - 1014 120.00 -8.10
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN30515306 9 COSMIC
COSN30676290 29 COSMIC
COSN31784781 34 COSMIC
COSN30466192 37 COSMIC
COSN30472075 41 COSMIC
COSN30535202 59 COSMIC
COSN18726769 60 COSMIC
COSN31580749 63 COSMIC
COSN31607941 66 COSMIC
COSN31572226 133 COSMIC
COSN32041915 139 COSMIC
COSN24838003 164 COSMIC
COSN30141026 200 COSMIC
COSN6149312 278 COSMIC
COSN29858954 403 COSMIC
COSN31579891 542 COSMIC
COSN31490768 544 COSMIC
COSN31529427 557 COSMIC
COSN31539550 656 COSMIC
COSN31481176 807 COSMIC
COSN31589850 836 COSMIC
COSN9853731 962 COSMIC
COSN22190498 1091 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1471756659 3 dbSNP
rs1249884190 4 dbSNP
rs775418300 6 dbSNP
rs1481679431 7 dbSNP
rs191157369 9 dbSNP
rs967963841 10 dbSNP
rs369633727 11 dbSNP
rs1323983820 13 dbSNP
rs765317407 14 dbSNP
rs1226161145 15 dbSNP
rs186430920 17 dbSNP
rs754096078 22 dbSNP
rs1224901385 27 dbSNP
rs1010633495 30 dbSNP
rs766562275 35 dbSNP
rs760756174 38 dbSNP
rs1006686808 44 dbSNP
rs368685787 50 dbSNP
rs536324322 51 dbSNP
rs1266357899 68 dbSNP
rs892201297 72 dbSNP
rs1029785680 82 dbSNP
rs994239610 87 dbSNP
rs1263691476 102 dbSNP
rs1052583675 103 dbSNP
rs1186529532 104 dbSNP
rs939530749 106 dbSNP
rs1476005547 113 dbSNP
rs897183949 116 dbSNP
rs928081443 118 dbSNP
rs1410656500 125 dbSNP
rs1355030986 131 dbSNP
rs567701312 133 dbSNP
rs1457304393 137 dbSNP
rs1289967863 144 dbSNP
rs1450619307 146 dbSNP
rs1394690178 153 dbSNP
rs1353190391 157 dbSNP
rs1333973351 159 dbSNP
rs148508354 174 dbSNP
rs948282958 176 dbSNP
rs906078679 177 dbSNP
rs1044959801 190 dbSNP
rs1162133031 194 dbSNP
rs181729936 196 dbSNP
rs1474622410 200 dbSNP
rs1342735847 212 dbSNP
rs534973472 224 dbSNP
rs950283884 231 dbSNP
rs745448898 236 dbSNP
rs190679143 238 dbSNP
rs895977742 240 dbSNP
rs375021378 242 dbSNP
rs940789818 244 dbSNP
rs935060138 246 dbSNP
rs186784477 253 dbSNP
rs551754938 263 dbSNP
rs907956883 270 dbSNP
rs1375402218 271 dbSNP
rs987921990 273 dbSNP
rs530265786 283 dbSNP
rs1029881358 284 dbSNP
rs563122027 287 dbSNP
rs975373959 288 dbSNP
rs964286334 290 dbSNP
rs1350051002 291 dbSNP
rs1392067424 293 dbSNP
rs1309292524 304 dbSNP
rs528830769 305 dbSNP
rs1231509052 309 dbSNP
rs979086782 313 dbSNP
rs1280947192 316 dbSNP
rs11537548 317 dbSNP
rs946628415 320 dbSNP
rs566258439 332 dbSNP
rs1273489211 337 dbSNP
rs1480779893 339 dbSNP
rs549647932 343 dbSNP
rs1264727705 347 dbSNP
rs985773881 361 dbSNP
rs1003667739 366 dbSNP
rs906712301 369 dbSNP
rs1167055695 378 dbSNP
rs1462730384 393 dbSNP
rs955262735 394 dbSNP
rs1045625620 395 dbSNP
rs1388747139 405 dbSNP
rs1029482822 406 dbSNP
rs948360703 408 dbSNP
rs972830419 408 dbSNP
rs1448032484 419 dbSNP
rs1373024378 423 dbSNP
rs1226048213 428 dbSNP
rs899409795 433 dbSNP
rs1037747071 435 dbSNP
rs940676692 436 dbSNP
rs529805336 445 dbSNP
rs1016952646 450 dbSNP
rs1460459699 451 dbSNP
rs1487882003 452 dbSNP
rs1254213880 453 dbSNP
rs987587444 453 dbSNP
rs560781940 456 dbSNP
rs1187199853 457 dbSNP
rs1429475652 459 dbSNP
rs933377423 459 dbSNP
rs76463286 460 dbSNP
rs1023248949 464 dbSNP
rs1348295595 465 dbSNP
rs530398977 466 dbSNP
rs1022163872 467 dbSNP
rs368050637 467 dbSNP
rs963962840 467 dbSNP
rs1441371238 468 dbSNP
rs1216049408 469 dbSNP
rs1310166122 474 dbSNP
rs989317358 484 dbSNP
rs1233490763 493 dbSNP
rs1274557038 495 dbSNP
rs145758745 515 dbSNP
rs1207462117 519 dbSNP
rs896009012 524 dbSNP
rs1486403820 532 dbSNP
rs1053190151 540 dbSNP
rs1411933724 546 dbSNP
rs1475033941 556 dbSNP
rs1165912079 557 dbSNP
rs1420200658 567 dbSNP
rs1455650068 572 dbSNP
rs1030594020 580 dbSNP
rs935090830 581 dbSNP
rs1223992489 596 dbSNP
rs1432676441 598 dbSNP
rs564910898 602 dbSNP
rs1361402659 604 dbSNP
rs780026790 610 dbSNP
rs1023841121 612 dbSNP
rs1326464228 614 dbSNP
rs1012828513 629 dbSNP
rs751693607 632 dbSNP
rs1241308378 636 dbSNP
rs1318001857 641 dbSNP
rs181328020 646 dbSNP
rs910864857 651 dbSNP
rs1301788970 658 dbSNP
rs1485549228 658 dbSNP
rs199517676 665 dbSNP
rs879288363 668 dbSNP
rs1471665319 674 dbSNP
rs555951187 675 dbSNP
rs1408768156 678 dbSNP
rs886459094 684 dbSNP
rs1294808149 686 dbSNP
rs149808147 694 dbSNP
rs867703496 698 dbSNP
rs922441545 699 dbSNP
rs933448251 701 dbSNP
rs1158940559 702 dbSNP
rs1421283993 714 dbSNP
rs1393042742 716 dbSNP
rs770667055 726 dbSNP
rs764346646 729 dbSNP
rs922002212 738 dbSNP
rs1433726099 748 dbSNP
rs1269423278 755 dbSNP
rs1192968989 766 dbSNP
rs1484967262 769 dbSNP
rs1226047759 788 dbSNP
rs1039578192 790 dbSNP
rs1347631162 797 dbSNP
rs774912764 798 dbSNP
rs942538035 807 dbSNP
rs1482219713 808 dbSNP
rs1181335839 809 dbSNP
rs1017057067 820 dbSNP
rs984602835 825 dbSNP
rs1471197196 826 dbSNP
rs377630552 834 dbSNP
rs1278659118 839 dbSNP
rs970109211 839 dbSNP
rs989367634 842 dbSNP
rs1234147963 843 dbSNP
rs1313269943 849 dbSNP
rs956597395 850 dbSNP
rs189779632 861 dbSNP
rs1355781755 868 dbSNP
rs1433605512 878 dbSNP
rs1023364872 883 dbSNP
rs746611579 887 dbSNP
rs982179268 888 dbSNP
rs1380016685 891 dbSNP
rs1370856952 892 dbSNP
rs1014523817 896 dbSNP
rs1306150232 900 dbSNP
rs552746407 903 dbSNP
rs369067737 904 dbSNP
rs1273893433 909 dbSNP
rs1439645125 913 dbSNP
rs1031804265 917 dbSNP
rs999018562 919 dbSNP
rs904692286 922 dbSNP
rs1401478552 928 dbSNP
rs1252329079 929 dbSNP
rs1373341566 937 dbSNP
rs963554398 949 dbSNP
rs1195397831 957 dbSNP
rs1388165689 957 dbSNP
rs1466401073 970 dbSNP
rs1016418181 973 dbSNP
rs1474924069 975 dbSNP
rs1421145925 982 dbSNP
rs1403129662 991 dbSNP
rs542451196 992 dbSNP
rs140485335 996 dbSNP
rs1005161430 1006 dbSNP
rs775801749 1007 dbSNP
rs775986033 1010 dbSNP
rs1379282567 1020 dbSNP
rs1325053194 1021 dbSNP
rs1227074363 1025 dbSNP
rs571892776 1028 dbSNP
rs1426737681 1040 dbSNP
rs886677039 1041 dbSNP
rs1272673925 1042 dbSNP
rs1043513084 1047 dbSNP
rs1194592673 1050 dbSNP
rs1489410648 1063 dbSNP
rs564955189 1066 dbSNP
rs1446239480 1070 dbSNP
rs889476958 1077 dbSNP
rs1200222452 1086 dbSNP
rs115212210 1092 dbSNP
rs1243602948 1100 dbSNP
rs1471635447 1101 dbSNP
rs1258285241 1106 dbSNP
rs1163744236 1112 dbSNP
rs545753214 1121 dbSNP
rs1462498157 1135 dbSNP
rs1306355607 1139 dbSNP
rs922472380 1141 dbSNP
rs947444264 1144 dbSNP
rs1036945858 1155 dbSNP
rs184461711 1157 dbSNP
rs909692485 1165 dbSNP
rs1053539199 1189 dbSNP
rs558213314 1197 dbSNP
rs1292834639 1199 dbSNP
rs147186118 1205 dbSNP
rs1235163438 1211 dbSNP
rs923853766 1211 dbSNP
rs982014571 1214 dbSNP
rs970807959 1216 dbSNP
rs915922994 1218 dbSNP
rs1257705738 1229 dbSNP
rs1296318330 1230 dbSNP
rs992749377 1240 dbSNP
rs960027889 1242 dbSNP
rs1031919028 1250 dbSNP
rs1461437922 1252 dbSNP
rs1475915264 1254 dbSNP
rs1422955503 1259 dbSNP
rs78019101 1265 dbSNP
rs549709112 1271 dbSNP
rs1016469128 1298 dbSNP
rs1387674251 1300 dbSNP
rs1415942027 1300 dbSNP
rs1022187457 1313 dbSNP
rs1010668514 1325 dbSNP
rs889498757 1342 dbSNP
rs1312523908 1344 dbSNP
rs1187193352 1360 dbSNP
rs1005046732 1361 dbSNP
rs1424695858 1362 dbSNP
rs1258718607 1364 dbSNP
rs1239766703 1368 dbSNP
rs1262349214 1370 dbSNP
rs1345484386 1371 dbSNP
rs951035094 1373 dbSNP
rs529421289 1374 dbSNP
rs1194536021 1381 dbSNP
rs1031002960 1382 dbSNP
rs1457736118 1383 dbSNP
rs1259317124 1386 dbSNP
rs1199968607 1396 dbSNP
rs1183184235 1405 dbSNP
rs1332114567 1419 dbSNP
rs1366010999 1419 dbSNP
rs1453004828 1433 dbSNP
rs1173454096 1439 dbSNP
rs1283170355 1442 dbSNP
rs1376422570 1445 dbSNP
rs1245083576 1450 dbSNP
rs997742947 1456 dbSNP
rs570254443 1458 dbSNP
rs900513755 1459 dbSNP
rs1391977580 1464 dbSNP
rs1049405723 1465 dbSNP
rs1039008654 1472 dbSNP
rs1390643194 1477 dbSNP
rs1011638940 1479 dbSNP
rs1368647617 1483 dbSNP
rs1400919261 1483 dbSNP
rs997888191 1485 dbSNP
rs1333354560 1488 dbSNP
rs1467247167 1493 dbSNP
rs1224868988 1496 dbSNP
rs201425997 1496 dbSNP
rs900829783 1501 dbSNP
rs1036978455 1502 dbSNP
rs939896120 1505 dbSNP
rs1162830224 1506 dbSNP
rs909731145 1507 dbSNP
rs1473262277 1508 dbSNP
rs1048670913 1509 dbSNP
rs1396134542 1510 dbSNP
rs1168621664 1517 dbSNP
rs1372669242 1518 dbSNP
rs1370525204 1522 dbSNP
rs1462589611 1531 dbSNP
rs948836698 1532 dbSNP
rs1392344897 1537 dbSNP
rs1180069717 1545 dbSNP
rs916019863 1546 dbSNP
rs1326490098 1550 dbSNP
rs1239312549 1551 dbSNP
rs868241370 1554 dbSNP
rs960060131 1555 dbSNP
rs550371436 1561 dbSNP
rs13017536 1562 dbSNP
rs1357987290 1565 dbSNP
rs564703869 1568 dbSNP
rs544651363 1570 dbSNP
rs1213624316 1572 dbSNP
rs1239145565 1575 dbSNP
rs1377455369 1576 dbSNP
rs1185099080 1583 dbSNP
rs1311288812 1586 dbSNP
rs528359366 1587 dbSNP
rs1173073683 1588 dbSNP
rs1460923032 1589 dbSNP
rs1368815068 1593 dbSNP
rs1192808 1595 dbSNP
rs1406067447 1606 dbSNP
rs542514158 1607 dbSNP
rs1157114709 1612 dbSNP
rs1419406527 1614 dbSNP
rs573724235 1623 dbSNP
rs1160919010 1632 dbSNP
rs1053590462 1634 dbSNP
rs1246677704 1635 dbSNP
rs953567485 1636 dbSNP
rs796616975 1638 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
     
Conditions HEK293
Disease 284996.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "HITS-CLIP data was present in GSM714642. RNA binding protein: AGO2. Condition:completeT1 "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714642
Method / RBP HITS-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000295317.3 | 3UTR | ACAGGUGGUGUUUCUAAAUAAUUGGCUGCUAUG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
CLIP-seq Support 2 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000295317.3 | 3UTR | ACAGGUGGUGUUUCUAAAUAAUUGGCUGCUAUGG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
180 hsa-miR-4524a-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT055251 CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2 2
MIRT055826 PLEKHA1 pleckstrin homology domain containing A1 2 2
MIRT060573 CCND1 cyclin D1 2 2
MIRT061013 C1ORF21 chromosome 1 open reading frame 21 2 6
MIRT064694 CCND2 cyclin D2 2 4
MIRT075268 SNTB2 syntrophin beta 2 2 4
MIRT079668 NAPG NSF attachment protein gamma 2 12
MIRT081651 CCNE1 cyclin E1 2 4
MIRT082996 PNPLA6 patatin like phospholipase domain containing 6 2 2
MIRT083463 RALGAPB Ral GTPase activating protein non-catalytic beta subunit 2 4
MIRT085755 RIF1 replication timing regulatory factor 1 2 2
MIRT086022 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2 2
MIRT087431 ZNRF3 zinc and ring finger 3 2 2
MIRT088786 SOCS5 suppressor of cytokine signaling 5 2 2
MIRT089221 ACTR2 ARP2 actin related protein 2 homolog 2 2
MIRT093696 PI4K2B phosphatidylinositol 4-kinase type 2 beta 2 6
MIRT095090 SEC24A SEC24 homolog A, COPII coat complex component 2 4
MIRT096249 CANX calnexin 2 2
MIRT100215 PPP1R11 protein phosphatase 1 regulatory inhibitor subunit 11 2 2
MIRT100746 VEGFA vascular endothelial growth factor A 2 12
MIRT100904 CD2AP CD2 associated protein 2 2
MIRT102647 UBN2 ubinuclein 2 2 10
MIRT103882 FOXK1 forkhead box K1 2 2
MIRT104246 DMTF1 cyclin D binding myb like transcription factor 1 2 2
MIRT106310 ZFHX4 zinc finger homeobox 4 2 6
MIRT107696 RECK reversion inducing cysteine rich protein with kazal motifs 2 2
MIRT114943 CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 2 2
MIRT117671 SCAMP4 secretory carrier membrane protein 4 2 2
MIRT133799 SKI SKI proto-oncogene 2 2
MIRT140167 SPRED1 sprouty related EVH1 domain containing 1 2 2
MIRT142279 DCTN5 dynactin subunit 5 2 8
MIRT143288 N4BP1 NEDD4 binding protein 1 2 2
MIRT165939 CREBRF CREB3 regulatory factor 2 2
MIRT175251 PSAT1 phosphoserine aminotransferase 1 2 6
MIRT186381 PNRC2 proline rich nuclear receptor coactivator 2 2 2
MIRT191470 PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A 2 2
MIRT196480 TAOK1 TAO kinase 1 2 2
MIRT201470 SNRPB2 small nuclear ribonucleoprotein polypeptide B2 2 8
MIRT204615 HSPE1-MOB4 HSPE1-MOB4 readthrough 2 8
MIRT204646 MOB4 MOB family member 4, phocein 2 8
MIRT204749 BZW1 basic leucine zipper and W2 domains 1 2 12
MIRT206031 NUP50 nucleoporin 50 2 6
MIRT211196 FGF2 fibroblast growth factor 2 2 4
MIRT229353 ZNF449 zinc finger protein 449 2 2
MIRT247138 WEE1 WEE1 G2 checkpoint kinase 2 4
MIRT249461 ZNF691 zinc finger protein 691 2 4
MIRT256314 CDC42SE2 CDC42 small effector 2 2 2
MIRT258419 WIPI2 WD repeat domain, phosphoinositide interacting 2 2 2
MIRT265083 CHEK1 checkpoint kinase 1 2 2
MIRT270561 SETD1B SET domain containing 1B 2 2
MIRT274749 RAB3IP RAB3A interacting protein 2 2
MIRT277515 PPP2R5C protein phosphatase 2 regulatory subunit B'gamma 2 4
MIRT289642 CBX2 chromobox 2 2 2
MIRT301001 MTMR3 myotubularin related protein 3 2 2
MIRT307149 CTDSPL CTD small phosphatase like 2 4
MIRT309021 USP53 ubiquitin specific peptidase 53 2 2
MIRT314100 PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 2 8
MIRT319338 CAPZA2 capping actin protein of muscle Z-line alpha subunit 2 2 2
MIRT320619 ZNRF2 zinc and ring finger 2 2 2
MIRT324285 LURAP1L leucine rich adaptor protein 1 like 2 2
MIRT446498 ASCC1 activating signal cointegrator 1 complex subunit 1 2 2
MIRT448437 TLL1 tolloid like 1 2 2
MIRT461537 ACTR3B ARP3 actin related protein 3 homolog B 2 2
MIRT463162 ZNF367 zinc finger protein 367 2 10
MIRT463493 ZC3H10 zinc finger CCCH-type containing 10 2 2
MIRT465154 TSC22D2 TSC22 domain family member 2 2 2
MIRT466418 TFAP2A transcription factor AP-2 alpha 2 8
MIRT468278 SFT2D2 SFT2 domain containing 2 2 2
MIRT469399 REL REL proto-oncogene, NF-kB subunit 2 6
MIRT471941 NR6A1 nuclear receptor subfamily 6 group A member 1 2 2
MIRT473688 MAPK8 mitogen-activated protein kinase 8 2 4
MIRT479618 CDC25A cell division cycle 25A 2 2
MIRT482098 AKT3 AKT serine/threonine kinase 3 2 4
MIRT483995 ATAD5 ATPase family, AAA domain containing 5 2 12
MIRT485205 PRKAR2A protein kinase cAMP-dependent type II regulatory subunit alpha 2 8
MIRT498763 C3orf38 chromosome 3 open reading frame 38 2 8
MIRT498961 ORC4 origin recognition complex subunit 4 2 8
MIRT499440 ODF2L outer dense fiber of sperm tails 2 like 2 8
MIRT500080 L2HGDH L-2-hydroxyglutarate dehydrogenase 2 8
MIRT500305 ZNF622 zinc finger protein 622 2 8
MIRT500410 ZMAT3 zinc finger matrin-type 3 2 8
MIRT500789 TLK1 tousled like kinase 1 2 6
MIRT500930 SRPR SRP receptor alpha subunit 2 6
MIRT500943 SREK1 splicing regulatory glutamic acid and lysine rich protein 1 2 8
MIRT501068 SMAD7 SMAD family member 7 2 8
MIRT501711 PARD6B par-6 family cell polarity regulator beta 2 2
MIRT502627 DDX3X DEAD-box helicase 3, X-linked 2 8
MIRT502910 CDCA4 cell division cycle associated 4 2 8
MIRT502935 CDC37L1 cell division cycle 37 like 1 2 8
MIRT504531 ZNF620 zinc finger protein 620 2 6
MIRT505106 YTHDC1 YTH domain containing 1 2 6
MIRT505337 TMEM245 transmembrane protein 245 2 6
MIRT505383 TMEM100 transmembrane protein 100 2 2
MIRT505678 SESTD1 SEC14 and spectrin domain containing 1 2 6
MIRT506157 PLAG1 PLAG1 zinc finger 2 8
MIRT506183 PHKA1 phosphorylase kinase regulatory subunit alpha 1 2 6
MIRT506475 MYO5A myosin VA 2 6
MIRT506826 KIF23 kinesin family member 23 2 6
MIRT507160 GAS2L3 growth arrest specific 2 like 3 2 2
MIRT507511 DYNLL2 dynein light chain LC8-type 2 2 4
MIRT507845 CCNE2 cyclin E2 2 6
MIRT510403 ZNF507 zinc finger protein 507 2 2
MIRT518078 TRIM35 tripartite motif containing 35 2 2
MIRT518982 NNT nicotinamide nucleotide transhydrogenase 2 4
MIRT521045 SLC2A3 solute carrier family 2 member 3 2 4
MIRT521190 SBNO1 strawberry notch homolog 1 2 6
MIRT522088 NUFIP2 NUFIP2, FMR1 interacting protein 2 2 4
MIRT524846 ARPP19 cAMP regulated phosphoprotein 19 2 2
MIRT527787 TMEM44 transmembrane protein 44 2 4
MIRT537803 EFNB2 ephrin B2 2 4
MIRT540830 GNAT1 G protein subunit alpha transducin 1 2 4
MIRT541140 PISD phosphatidylserine decarboxylase 2 2
MIRT541419 CBX4 chromobox 4 2 2
MIRT543517 PRSS21 protease, serine 21 2 2
MIRT543824 GSG1 germ cell associated 1 2 2
MIRT544959 UGT2B4 UDP glucuronosyltransferase family 2 member B4 2 2
MIRT545179 MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2 4
MIRT545335 CCDC83 coiled-coil domain containing 83 2 2
MIRT545518 RSL24D1 ribosomal L24 domain containing 1 2 2
MIRT545670 DECR1 2,4-dienoyl-CoA reductase 1 2 2
MIRT545931 ZBTB44 zinc finger and BTB domain containing 44 2 4
MIRT546102 USP48 ubiquitin specific peptidase 48 2 4
MIRT546598 SALL1 spalt like transcription factor 1 2 4
MIRT546626 RTN4 reticulon 4 2 2
MIRT547651 KPNA3 karyopherin subunit alpha 3 2 2
MIRT547987 HCFC2 host cell factor C2 2 4
MIRT548717 CRK CRK proto-oncogene, adaptor protein 2 2
MIRT548931 CDK17 cyclin dependent kinase 17 2 2
MIRT549067 CACUL1 CDK2 associated cullin domain 1 2 2
MIRT549266 ASH1L ASH1 like histone lysine methyltransferase 2 2
MIRT550460 OSCAR osteoclast associated, immunoglobulin-like receptor 2 4
MIRT550806 FAM229B family with sequence similarity 229 member B 2 2
MIRT552024 DNAJC10 DnaJ heat shock protein family (Hsp40) member C10 2 2
MIRT552334 ZNF704 zinc finger protein 704 2 2
MIRT552732 YRDC yrdC N6-threonylcarbamoyltransferase domain containing 2 2
MIRT553795 SZRD1 SUZ RNA binding domain containing 1 2 4
MIRT554694 RNF149 ring finger protein 149 2 2
MIRT555133 PTPRD protein tyrosine phosphatase, receptor type D 2 2
MIRT555264 PRDM4 PR/SET domain 4 2 2
MIRT556848 KANK1 KN motif and ankyrin repeat domains 1 2 4
MIRT557474 GPR27 G protein-coupled receptor 27 2 4
MIRT558018 EXT1 exostosin glycosyltransferase 1 2 2
MIRT558498 CYP26B1 cytochrome P450 family 26 subfamily B member 1 2 4
MIRT558579 CREBL2 cAMP responsive element binding protein like 2 2 4
MIRT558610 COX6B1 cytochrome c oxidase subunit 6B1 2 4
MIRT558650 CNKSR3 CNKSR family member 3 2 2
MIRT558986 CA8 carbonic anhydrase 8 2 2
MIRT559141 BTN3A3 butyrophilin subfamily 3 member A3 2 2
MIRT559327 ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) 2 2
MIRT562021 LANCL1 LanC like 1 2 2
MIRT562869 KIAA1456 KIAA1456 2 2
MIRT563074 SLC25A12 solute carrier family 25 member 12 2 2
MIRT563496 DLGAP3 DLG associated protein 3 2 2
MIRT563890 RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2 2
MIRT564311 CCNT1 cyclin T1 2 2
MIRT564942 XKR7 XK related 7 2 2
MIRT564979 WNK3 WNK lysine deficient protein kinase 3 2 2
MIRT565423 TEF TEF, PAR bZIP transcription factor 2 2
MIRT566824 MAP3K7 mitogen-activated protein kinase kinase kinase 7 2 2
MIRT571961 KIF5B kinesin family member 5B 2 2
MIRT575877 Cask calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2 3
MIRT576523 Txlna taxilin alpha 2 2
MIRT614693 TRAK1 trafficking kinesin protein 1 2 2
MIRT616065 ZC3H14 zinc finger CCCH-type containing 14 2 2
MIRT618838 ASAH2B N-acylsphingosine amidohydrolase 2B 2 2
MIRT624626 ATXN2 ataxin 2 2 2
MIRT624652 ASAH2 N-acylsphingosine amidohydrolase 2 2 2
MIRT640314 MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2 2
MIRT659248 CUL3 cullin 3 2 2
MIRT680972 DCAF17 DDB1 and CUL4 associated factor 17 2 2
MIRT682261 RS1 retinoschisin 1 2 2
MIRT682505 GLP2R glucagon like peptide 2 receptor 2 2
MIRT693904 HNRNPA1L2 heterogeneous nuclear ribonucleoprotein A1-like 2 2 2
MIRT699214 SLCO3A1 solute carrier organic anion transporter family member 3A1 2 2
MIRT699373 SLC30A6 solute carrier family 30 member 6 2 2
MIRT699451 SLC16A9 solute carrier family 16 member 9 2 2
MIRT701230 OCRL OCRL, inositol polyphosphate-5-phosphatase 2 2
MIRT702849 HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 2 2
MIRT706163 CASK calcium/calmodulin dependent serine protein kinase 2 3
MIRT718990 UTP15 UTP15, small subunit processome component 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-miR-4524a-5p Gemcitabine 60750 NSC613327 approved resistant cell line (PANC-1) (1500 ng/ml)
hsa-miR-4524a-5p Cetuximab resistant tissue (colorectal carcinoma)

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