miRTarBase - #MIRT555119


—
pre-miRNA Information
pre-miRNA hsa-mir-3675   
Genomic Coordinates chr1: 16858949 - 16859021
Description Homo sapiens miR-3675 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-3675-5p
Sequence 12| UAUGGGGCUUCUGUAGAGAUUUC |34
Evidence Experimental
Experiments Illumina
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs1229940041 1 dbSNP
rs1184422098 2 dbSNP
rs768029583 3 dbSNP
rs202014433 6 dbSNP
rs774834919 7 dbSNP
rs1484376029 8 dbSNP
rs771338088 8 dbSNP
rs749521347 10 dbSNP
rs773421450 12 dbSNP
rs1250672393 14 dbSNP
rs769780471 15 dbSNP
rs781028022 16 dbSNP
rs1315377622 17 dbSNP
rs754885466 18 dbSNP
rs746860289 20 dbSNP
rs1330333643 23 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol PUM2   
Synonyms PUMH2, PUML2
Description pumilio RNA binding family member 2
Transcript NM_015317   
Expression
Putative miRNA Targets on PUM2
3'UTR of PUM2
(miRNA target sites are highlighted)		 
>PUM2|NM_015317|3'UTR
   1 ATTACAGGAGCAAGAGAAAGAAGATAATTTAACCATGTGAAAAGAATTTTTTTGTGTGTGAATTATCAAAACACAACTCA
  81 ACTATGAATCTTCAATTTTTTTTTAAAGCAAAACTATTTATTGACTTTATTCATCCATTTGTAAATTTTTTAAGGTTCTT
 161 GTGTATATTTGGGGGGTGGGGGATGAATTATAAATTATATTCAGCCCTGAGTGGAGACCTATCAGATTGGATTGCTGGCA
 241 AAGCACAGAATGCCTGTATATGATGTAACTGTATCAAAAATAAAAAGCTGTCACATATTTTGTAAATTTTTACCTTGTAA
 321 AGTCACAAAAATAGTTTTTAAAGGAAAAAGTACAGTATTCTTTTAATAAACTGGCTCACAGTCTGGTAGGTCTACAACCC
 401 CATAGCACAACAGGTTTATAGAGATGTATATAGAATTATAGTCCTTATTTTTTTCCTTTGCGTGAAACCTTTTATAACAG
 481 ATTAACAATCAACTGCATAAATATTATTAATATTTTAAAAAGAGTTAAGTTGTATTTTGATAATTCACAAACTATCATGC
 561 AAATAACGAGTAAGTAGACAAGAATAAAGTGGTTTGAGATGAAAAGAACCTAACATTATTTACAGTAGATGTGGTTTTAA
 641 TACAATTACTGCCCTAAAATGTCTCTGGCAATGTACAGAAATATTGTATATACTTACATATGTAATTGTTGTAAGAGTTA
 721 AATACAAAATCATGGTGACACTTCCAATTAAGTGCACTAAATGAAAAGTTAAGTCACTTATTAACTTTTCAGTTTGGTTT
 801 GCAATGAGAAAGAGTGGAAATTTGTATTTTGTTTTGCTTATAGAATTACAGACATGTTGAGGAAGTGTTGAGCTTTATTT
 881 TGCTTTTTCATAGAGGCAGAAAGTAGGAACCAGATAGAGATGAAAAGGGGCCACTGAAAAGTGAATTTGATAGCTCAGCA
 961 TTTAAGCATGATTACATATTCAGATAGCTCTTTTTGCTTTCTATAAATATATGCATTGTGTGTGTAGTAATAGATGTAAG
1041 TTTACACTTTGAAAGGAAATCTTGTTTCAATGTTTATTATAAAAGCCTTGCTAATTTAGTAGTGATGCTTTCCTTGGTTG
1121 TACAGGTGTACATTTGTAAACCTTCATGCTGTAAATGGAATTTGTTTTATCTCTTTGGGATACATTTGCATTTTAGTGTA
1201 CATTTACGTCCCTGCCCTCTTTGACCTGGCAATATAGTGTTGTATAATGTAAATTTATTTCTCCAAATCGAGAGTGATTT
1281 TTTAAAAATTTTTTATCTTTATATGGTTTCAGAAGTATGAACCAGCTTTCTTTTTATTATTGTGAGATCATTTTGTTTTA
1361 TAACATAGTTGTTGACTGTTAATATGGACCTGCTAGAATTTGGATCACTTTCAATTGAAGTCAGGGTATTGTGCATAATA
1441 GAAAGTATTGGACTGAGATATTTGGTTACCATGGAGGCCAATGCTTTTTTCATCTTATTAAATGTGATGTGACTTTTTTC
1521 TTTGTACAGAAGAGTACTGTATTTTTGAATAGCCTACTCCCAAGTAAGAGCAAATCTGTATGATAACATTTTTTCCTCTG
1601 GACATAAGACATAACAGTAACACGATGTACATTTACAAGCGGCCTTATGTACATTTCCCAACAATCTTTTTAAGGCAAAA
1681 TTGTGACCATATGTGTATAATTAAAATCGTTTTTAATCCTTTGCCTATGAAAATATTTTGGAAAAAAACTTGCTGTGTAT
1761 ATTCAGTTTCTGAAAGATAAAGAAAGTGCTTTGTATTTTGTTGAAGTCAGTATTTTGTATAAACATTTATGTTGACCCAC
1841 TTATGTTCAGTGCTGAAAACTAAAATGAACATGCTATTCTGTCAGCTGAATATGGAAGAGATCTTTTTTTACTAGAGATC
1921 TGCAGAAGAAACGCAATCTTCTGAGCACAATATGGAATCTAAAGGTTTTATCACTTAGTTGTTCATATTATGAACCTAAA
2001 AATAATGGCATAAAGTTTGGGGATGCCAGGCATACTTTTTCATGTTTGGTGTTGAGTTATTTTACTTTTCTAACCCAACA
2081 TTCCTTGGTGAGACCATTAAATCCAAACACTTGTCACCGTTCCTTCTCATAGTCACTCTGGGTCATCAGCATGTCCCAGT
2161 CACTGCAGCAACGCCTTGTGTTTGTTTCATTTTTTTAAAACCCACACAAAGCCGCTGTCTCACTTTTTCCTACTTTACCA
2241 ACCTCAGAGTATTTCGGCCCGTATCGAACTTTTGTTCTCAGTATCAGCCCATGGTTTCAGGATCAAAGCTGTCATGTTGG
2321 AGATTGGTAATGGCTTTCCTGTCTTTGTACAGTTGAATTCCTAGTCTTCCTTCATCCTTGCCCTCTGTTGGCACAGGCAT
2401 TATCTCTGCAATTTTAGAAAATGACAAGTAGAGAATACTACATTGAGAAACTAAACCCTCTTCTTGGGGTCCTGATACTC
2481 ATTCCCATTTGTCCCAGTGCTGACAACCCAATCTTCCCAATACTTTCAGGCCTGCTCTACAAAAGTACCTGTTCTTGTAG
2561 AAATTTTACAGTCTGCCATTTTGGGTGCCCACCCCAATTTTTACCTTTTAGTAAGTTGGCATGAAATTTTGGTAAAATCT
2641 GAAAATCACATTTCAGAATAAAACAATTGGGCAAAACTACCTAGGCTTTACTCTTGAGTGTCTCCTTTTGATAGGGATTG
2721 TTTCTGGACCAGTTTGTCTAAGTCCTGGCTCTTATTGGTTCATATGAAATAATGTTAACTTCACTTCTTTGTATATTATG
2801 TATAAATTAGAAAATGAAAAATGTGTGAATAACATTGTATGAAATAAACCTGGTCTTGTGTTTTTCTCTAGATAAAATAC
2881 CCCTCTGTACCTCAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1 
miRNA  3' cuuuagAGAUGUCUUCGGGGUAu 5'
                |||||| |  |||||| 
Target 5' ggtaggTCTACA-A--CCCCATa 3'
 385 - 404 131.00 -15.80
2 
miRNA  3' cuuuagAGAUG-UCUUCGGGGUAu 5'
                |:||| || :|||::|| 
Target 5' tgtacaTTTACAAGCGGCCTTATg 3'
 1626 - 1649 129.00 -13.10
3 
miRNA  3' cuUUAGAGAUGUC-UU-CGGGGUAu 5'
            |:|| ||:||| || |||:::| 
Target 5' ccAGTCACTGCAGCAACGCCTTGTg 3'
 2156 - 2180 125.00 -17.40
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
COSN31539564 25 COSMIC
COSN31565786 46 COSMIC
COSN30464293 47 COSMIC
COSN31516134 48 COSMIC
COSN2375680 53 COSMIC
COSN30170520 79 COSMIC
COSN20068630 96 COSMIC
COSN30537753 104 COSMIC
COSN8608442 225 COSMIC
COSN24557208 282 COSMIC
COSN1819413 293 COSMIC
COSN31607339 337 COSMIC
COSN1819412 386 COSMIC
COSN30175280 568 COSMIC
COSN26253021 585 COSMIC
COSN31566055 606 COSMIC
COSN31490824 628 COSMIC
COSN28773706 1020 COSMIC
COSN31589430 1102 COSMIC
COSN31536411 1135 COSMIC
COSN32161188 1158 COSMIC
COSN30159557 1207 COSMIC
COSN1819410 1288 COSMIC
COSN31479829 1330 COSMIC
COSN6933144 1456 COSMIC
COSN8277672 1576 COSMIC
COSN31544242 1588 COSMIC
COSN5128849 1666 COSMIC
COSN31542920 1709 COSMIC
COSN19658750 1779 COSMIC
COSN31550730 1870 COSMIC
COSN9871816 1875 COSMIC
COSN31600993 2027 COSMIC
COSN28644180 2172 COSMIC
COSN31521442 2196 COSMIC
COSN9304707 2348 COSMIC
COSN28452906 2609 COSMIC
COSN28750693 2683 COSMIC
COSN22458388 2729 COSMIC
COSN31535452 2739 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs780176333 5 dbSNP
rs1322659436 6 dbSNP
rs759145240 13 dbSNP
rs774105503 22 dbSNP
rs770335793 23 dbSNP
rs762593569 25 dbSNP
rs1204706839 27 dbSNP
rs201821086 28 dbSNP
rs897965276 31 dbSNP
rs770369188 33 dbSNP
rs1232652206 38 dbSNP
rs1327056611 39 dbSNP
rs1036547409 40 dbSNP
rs1297771407 41 dbSNP
rs764366674 44 dbSNP
rs748686766 46 dbSNP
rs1024132865 47 dbSNP
rs535100565 52 dbSNP
rs538092312 54 dbSNP
rs932007049 61 dbSNP
rs11539764 65 dbSNP
rs569978420 66 dbSNP
rs923276841 72 dbSNP
rs1411448276 73 dbSNP
rs1004467621 74 dbSNP
rs1391679268 76 dbSNP
rs1031035402 80 dbSNP
rs1324589122 81 dbSNP
rs1302828560 84 dbSNP
rs1331147862 88 dbSNP
rs1226006284 90 dbSNP
rs1461930023 93 dbSNP
rs935413015 96 dbSNP
rs187277948 104 dbSNP
rs1275780641 105 dbSNP
rs977304134 105 dbSNP
rs1490344174 119 dbSNP
rs1197857384 121 dbSNP
rs1373362730 123 dbSNP
rs903819335 127 dbSNP
rs1192494005 132 dbSNP
rs1029258701 141 dbSNP
rs182198974 145 dbSNP
rs1252498910 146 dbSNP
rs1214377435 151 dbSNP
rs1035337942 152 dbSNP
rs1470267349 152 dbSNP
rs1271501208 154 dbSNP
rs902050620 155 dbSNP
rs1381175635 162 dbSNP
rs571002953 171 dbSNP
rs1292737151 172 dbSNP
rs370282344 178 dbSNP
rs1272241951 181 dbSNP
rs1005069958 182 dbSNP
rs1359213866 187 dbSNP
rs1015490866 195 dbSNP
rs1267768137 206 dbSNP
rs12996918 207 dbSNP
rs1489052904 208 dbSNP
rs886203617 218 dbSNP
rs1259732596 221 dbSNP
rs1048775353 225 dbSNP
rs1368294759 240 dbSNP
rs1006430470 241 dbSNP
rs888021536 246 dbSNP
rs189572002 251 dbSNP
rs141092410 253 dbSNP
rs1166580224 256 dbSNP
rs1350404483 258 dbSNP
rs996447099 261 dbSNP
rs926926944 262 dbSNP
rs1286661842 274 dbSNP
rs1044323443 280 dbSNP
rs1390160997 281 dbSNP
rs1409237576 281 dbSNP
rs949993456 285 dbSNP
rs1380044252 288 dbSNP
rs1226966582 289 dbSNP
rs1315262639 290 dbSNP
rs759594330 293 dbSNP
rs1238939334 294 dbSNP
rs1396970185 299 dbSNP
rs1170220263 303 dbSNP
rs1040425381 305 dbSNP
rs1433152198 311 dbSNP
rs1394692402 313 dbSNP
rs1242777272 319 dbSNP
rs1482361902 331 dbSNP
rs1194425013 338 dbSNP
rs1455644969 347 dbSNP
rs548574793 350 dbSNP
rs917091850 353 dbSNP
rs1231191057 360 dbSNP
rs531755133 364 dbSNP
rs776324546 368 dbSNP
rs1418472328 370 dbSNP
rs988646708 375 dbSNP
rs956036198 386 dbSNP
rs935393673 394 dbSNP
rs1174997872 410 dbSNP
rs924027516 411 dbSNP
rs1041932921 414 dbSNP
rs979480180 422 dbSNP
rs947207100 439 dbSNP
rs1380315630 451 dbSNP
rs563536133 452 dbSNP
rs914392349 455 dbSNP
rs1287030355 457 dbSNP
rs958628242 461 dbSNP
rs1346518699 462 dbSNP
rs1310725368 464 dbSNP
rs968077105 468 dbSNP
rs774919556 469 dbSNP
rs1277212211 474 dbSNP
rs1472873405 482 dbSNP
rs1441444645 483 dbSNP
rs200397852 484 dbSNP
rs60730953 484 dbSNP
rs1426556689 488 dbSNP
rs530989119 503 dbSNP
rs1309687640 510 dbSNP
rs1176380434 517 dbSNP
rs868053938 517 dbSNP
rs879939038 522 dbSNP
rs1014712207 523 dbSNP
rs113976543 525 dbSNP
rs952210059 525 dbSNP
rs1374554090 529 dbSNP
rs1174513585 532 dbSNP
rs1220968321 533 dbSNP
rs1029176912 543 dbSNP
rs1307065438 549 dbSNP
rs1202840465 554 dbSNP
rs1276492572 554 dbSNP
rs1416333407 556 dbSNP
rs996415936 556 dbSNP
rs1244874336 563 dbSNP
rs368786557 563 dbSNP
rs902118765 567 dbSNP
rs552487565 568 dbSNP
rs1447281368 572 dbSNP
rs1167167008 576 dbSNP
rs1372774849 577 dbSNP
rs1430756593 578 dbSNP
rs1303104046 580 dbSNP
rs1348588869 585 dbSNP
rs1438707396 601 dbSNP
rs77268134 606 dbSNP
rs765503606 609 dbSNP
rs1005070738 610 dbSNP
rs1299593340 612 dbSNP
rs886569805 618 dbSNP
rs760263948 621 dbSNP
rs34025470 622 dbSNP
rs946808528 635 dbSNP
rs892942380 640 dbSNP
rs1453191251 643 dbSNP
rs1221749721 645 dbSNP
rs1241003353 649 dbSNP
rs564169368 650 dbSNP
rs1190077014 660 dbSNP
rs1055583493 661 dbSNP
rs1450493356 667 dbSNP
rs1162967592 671 dbSNP
rs994537217 681 dbSNP
rs1211180425 684 dbSNP
rs1412346827 693 dbSNP
rs1313541066 694 dbSNP
rs1281589595 697 dbSNP
rs1344650760 698 dbSNP
rs1222697327 702 dbSNP
rs1351400817 703 dbSNP
rs1322837555 725 dbSNP
rs1366133038 731 dbSNP
rs1290145537 737 dbSNP
rs937242101 747 dbSNP
rs905574492 754 dbSNP
rs531999785 763 dbSNP
rs1358460207 774 dbSNP
rs1313220228 775 dbSNP
rs1282993676 776 dbSNP
rs950035975 777 dbSNP
rs185106612 781 dbSNP
rs1209992605 783 dbSNP
rs932742985 784 dbSNP
rs35633201 791 dbSNP
rs940336958 794 dbSNP
rs907537638 796 dbSNP
rs566493695 797 dbSNP
rs1236062106 801 dbSNP
rs1053419606 808 dbSNP
rs1401353311 811 dbSNP
rs1474079855 812 dbSNP
rs951914043 812 dbSNP
rs1455727575 814 dbSNP
rs1161381382 818 dbSNP
rs1414186863 826 dbSNP
rs540065041 830 dbSNP
rs1395658131 832 dbSNP
rs1421235309 838 dbSNP
rs541381936 839 dbSNP
rs1332004910 841 dbSNP
rs1475136633 842 dbSNP
rs1448432842 843 dbSNP
rs1419066258 846 dbSNP
rs1326900781 852 dbSNP
rs1183944457 859 dbSNP
rs925770770 861 dbSNP
rs979553727 864 dbSNP
rs974944996 865 dbSNP
rs1198335966 866 dbSNP
rs1280246617 870 dbSNP
rs1484065569 872 dbSNP
rs1444518141 878 dbSNP
rs1188614492 883 dbSNP
rs1251739349 887 dbSNP
rs968108990 892 dbSNP
rs966274495 896 dbSNP
rs1471895827 897 dbSNP
rs1184512496 917 dbSNP
rs1412770953 920 dbSNP
rs921958291 921 dbSNP
rs1171070060 922 dbSNP
rs1404544568 944 dbSNP
rs974785495 957 dbSNP
rs1000188033 972 dbSNP
rs1307173129 975 dbSNP
rs1240001121 976 dbSNP
rs1348619665 979 dbSNP
rs1411557987 981 dbSNP
rs902488727 982 dbSNP
rs966417939 984 dbSNP
rs1330030362 990 dbSNP
rs1230370003 992 dbSNP
rs1257412530 1003 dbSNP
rs1019196177 1007 dbSNP
rs1005511755 1010 dbSNP
rs950918571 1014 dbSNP
rs1022731476 1024 dbSNP
rs1274354835 1030 dbSNP
rs1482389841 1041 dbSNP
rs1207885106 1050 dbSNP
rs545712762 1051 dbSNP
rs1269428082 1062 dbSNP
rs1010979220 1069 dbSNP
rs529809024 1070 dbSNP
rs1055551998 1071 dbSNP
rs937210825 1095 dbSNP
rs907055539 1096 dbSNP
rs1308579959 1101 dbSNP
rs1389859356 1111 dbSNP
rs1384577431 1115 dbSNP
rs76163405 1118 dbSNP
rs539784108 1120 dbSNP
rs561102719 1121 dbSNP
rs1227185775 1124 dbSNP
rs554105910 1125 dbSNP
rs1297380680 1132 dbSNP
rs1023106092 1134 dbSNP
rs1013937554 1136 dbSNP
rs895439991 1141 dbSNP
rs1053078454 1145 dbSNP
rs934572397 1146 dbSNP
rs907519186 1147 dbSNP
rs904382754 1153 dbSNP
rs1042899417 1155 dbSNP
rs984884914 1162 dbSNP
rs932445554 1164 dbSNP
rs1208195789 1169 dbSNP
rs1269529341 1180 dbSNP
rs534419811 1183 dbSNP
rs1452445635 1184 dbSNP
rs1188197272 1192 dbSNP
rs1269833211 1194 dbSNP
rs149108625 1195 dbSNP
rs1451109810 1207 dbSNP
rs548703664 1208 dbSNP
rs975193487 1214 dbSNP
rs921711929 1221 dbSNP
rs745789106 1232 dbSNP
rs538201345 1239 dbSNP
rs1461412976 1242 dbSNP
rs145036518 1256 dbSNP
rs1294829589 1258 dbSNP
rs1390788887 1265 dbSNP
rs912082049 1270 dbSNP
rs1318156372 1271 dbSNP
rs1427118422 1275 dbSNP
rs983759149 1283 dbSNP
rs1419186800 1284 dbSNP
rs950949160 1288 dbSNP
rs967393177 1289 dbSNP
rs1022277199 1295 dbSNP
rs1027806699 1295 dbSNP
rs550044075 1297 dbSNP
rs973552747 1300 dbSNP
rs533100944 1302 dbSNP
rs1208117763 1315 dbSNP
rs1246431577 1317 dbSNP
rs1033692803 1322 dbSNP
rs564287663 1329 dbSNP
rs1014415480 1330 dbSNP
rs1166869167 1334 dbSNP
rs1003588571 1341 dbSNP
rs1456263654 1346 dbSNP
rs907024510 1347 dbSNP
rs895524355 1355 dbSNP
rs745335457 1363 dbSNP
rs1289859215 1376 dbSNP
rs770730860 1384 dbSNP
rs1394597187 1390 dbSNP
rs1223589070 1393 dbSNP
rs886392730 1396 dbSNP
rs745433087 1400 dbSNP
rs1266304129 1408 dbSNP
rs998803299 1409 dbSNP
rs114453985 1414 dbSNP
rs1271958606 1416 dbSNP
rs544403091 1426 dbSNP
rs1482166477 1433 dbSNP
rs1215410993 1435 dbSNP
rs370939590 1439 dbSNP
rs1183324728 1441 dbSNP
rs1258146086 1442 dbSNP
rs1042972775 1443 dbSNP
rs1472215631 1449 dbSNP
rs531055637 1450 dbSNP
rs778874484 1453 dbSNP
rs921599065 1458 dbSNP
rs757286387 1461 dbSNP
rs944451798 1465 dbSNP
rs1357013208 1476 dbSNP
rs376198259 1477 dbSNP
rs527488630 1481 dbSNP
rs1356725081 1491 dbSNP
rs912050586 1495 dbSNP
rs373001184 1498 dbSNP
rs1352442340 1499 dbSNP
rs911919908 1507 dbSNP
rs1354351792 1509 dbSNP
rs983842335 1522 dbSNP
rs1198786206 1529 dbSNP
rs915514269 1535 dbSNP
rs1171530096 1538 dbSNP
rs1212041724 1548 dbSNP
rs989700703 1557 dbSNP
rs74376146 1560 dbSNP
rs78759423 1561 dbSNP
rs76483608 1562 dbSNP
rs74341922 1563 dbSNP
rs1482710904 1571 dbSNP
rs1391616334 1574 dbSNP
rs1202972072 1583 dbSNP
rs1253819863 1585 dbSNP
rs1191277962 1595 dbSNP
rs1190053939 1596 dbSNP
rs1422701407 1596 dbSNP
rs1434534073 1602 dbSNP
rs1453272598 1608 dbSNP
rs561408445 1611 dbSNP
rs541568235 1623 dbSNP
rs920861205 1624 dbSNP
rs1306744549 1626 dbSNP
rs1372886949 1627 dbSNP
rs1479592331 1630 dbSNP
rs1484303326 1636 dbSNP
rs973583827 1641 dbSNP
rs1443029942 1651 dbSNP
rs970236459 1652 dbSNP
rs970807117 1653 dbSNP
rs1232126715 1659 dbSNP
rs569455689 1660 dbSNP
rs775953451 1661 dbSNP
rs575631552 1666 dbSNP
rs1205579328 1687 dbSNP
rs1005156629 1689 dbSNP
rs1278464923 1698 dbSNP
rs1023554513 1701 dbSNP
rs992616512 1703 dbSNP
rs1049409828 1709 dbSNP
rs1220266539 1722 dbSNP
rs1244455486 1724 dbSNP
rs994773234 1727 dbSNP
rs900139582 1729 dbSNP
rs1193914296 1734 dbSNP
rs1303449269 1747 dbSNP
rs1038748675 1749 dbSNP
rs35997772 1749 dbSNP
rs944420704 1750 dbSNP
rs1167032254 1752 dbSNP
rs1422355613 1752 dbSNP
rs562373332 1753 dbSNP
rs1348238818 1754 dbSNP
rs1438641206 1755 dbSNP
rs1326840431 1756 dbSNP
rs1364639294 1762 dbSNP
rs1264264160 1770 dbSNP
rs1299526426 1776 dbSNP
rs1340048388 1780 dbSNP
rs1412058405 1783 dbSNP
rs1042554455 1787 dbSNP
rs1031391654 1793 dbSNP
rs546461465 1799 dbSNP
rs998541640 1806 dbSNP
rs1323026296 1807 dbSNP
rs1171377449 1821 dbSNP
rs1433661329 1824 dbSNP
rs1213712974 1831 dbSNP
rs1377725621 1839 dbSNP
rs1247038094 1843 dbSNP
rs577432320 1844 dbSNP
rs1177563573 1847 dbSNP
rs1244161405 1849 dbSNP
rs1475922382 1850 dbSNP
rs1417294374 1860 dbSNP
rs35718653 1866 dbSNP
rs1412186611 1869 dbSNP
rs945504486 1885 dbSNP
rs554470534 1895 dbSNP
rs1198602419 1897 dbSNP
rs1021560626 1902 dbSNP
rs915417210 1905 dbSNP
rs111576078 1911 dbSNP
rs1165739256 1914 dbSNP
rs777718897 1919 dbSNP
rs899704255 1920 dbSNP
rs534343279 1932 dbSNP
rs1182734435 1933 dbSNP
rs1041257818 1936 dbSNP
rs1483923769 1937 dbSNP
rs1282369581 1942 dbSNP
rs575094629 1944 dbSNP
rs555089690 1949 dbSNP
rs1255081352 1950 dbSNP
rs1210476688 1951 dbSNP
rs1210243452 1960 dbSNP
rs1284460094 1961 dbSNP
rs1447952558 1970 dbSNP
rs938281272 1975 dbSNP
rs538387463 1979 dbSNP
rs1476464140 1984 dbSNP
rs1483683608 1985 dbSNP
rs890547260 1990 dbSNP
rs1455676276 1992 dbSNP
rs1047778770 1999 dbSNP
rs929308324 2025 dbSNP
rs1257887804 2029 dbSNP
rs569250566 2030 dbSNP
rs1385875554 2031 dbSNP
rs1413704970 2038 dbSNP
rs920558944 2039 dbSNP
rs1236956716 2046 dbSNP
rs1037958342 2049 dbSNP
rs1287601867 2051 dbSNP
rs1348109343 2053 dbSNP
rs1229637460 2054 dbSNP
rs948957009 2055 dbSNP
rs1016059424 2059 dbSNP
rs1316910323 2061 dbSNP
rs1289527493 2072 dbSNP
rs756348771 2078 dbSNP
rs916111080 2079 dbSNP
rs993419094 2083 dbSNP
rs1212268698 2095 dbSNP
rs1251670659 2096 dbSNP
rs552320591 2096 dbSNP
rs1471661707 2115 dbSNP
rs539036383 2118 dbSNP
rs370467049 2119 dbSNP
rs1396693454 2122 dbSNP
rs1027501681 2132 dbSNP
rs1307354366 2134 dbSNP
rs1368556531 2138 dbSNP
rs994743902 2145 dbSNP
rs1395129070 2154 dbSNP
rs900443861 2165 dbSNP
rs1017278841 2171 dbSNP
rs1043400 2172 dbSNP
rs1304133991 2173 dbSNP
rs890137700 2174 dbSNP
rs1042492810 2175 dbSNP
rs945166007 2180 dbSNP
rs893940105 2181 dbSNP
rs767700343 2182 dbSNP
rs1053911444 2184 dbSNP
rs977136093 2190 dbSNP
rs1362656603 2196 dbSNP
rs149918549 2197 dbSNP
rs938260149 2197 dbSNP
rs968407096 2209 dbSNP
rs867287089 2211 dbSNP
rs867129575 2213 dbSNP
rs996789243 2214 dbSNP
rs547860851 2219 dbSNP
rs1167721664 2222 dbSNP
rs1388306060 2236 dbSNP
rs545718263 2238 dbSNP
rs964291179 2239 dbSNP
rs982334235 2241 dbSNP
rs755055638 2243 dbSNP
rs1389424148 2245 dbSNP
rs949381393 2246 dbSNP
rs1384520639 2250 dbSNP
rs1327521384 2252 dbSNP
rs1442185053 2255 dbSNP
rs531340297 2255 dbSNP
rs1306319981 2256 dbSNP
rs751640508 2257 dbSNP
rs1008496094 2258 dbSNP
rs562618711 2260 dbSNP
rs140995141 2261 dbSNP
rs146566387 2263 dbSNP
rs77031565 2265 dbSNP
rs899198282 2266 dbSNP
rs1017493053 2269 dbSNP
rs540967428 2272 dbSNP
rs1367765294 2274 dbSNP
rs13394115 2278 dbSNP
rs948722481 2280 dbSNP
rs1394841667 2287 dbSNP
rs1211158122 2291 dbSNP
rs1456361857 2296 dbSNP
rs1326655628 2301 dbSNP
rs890087446 2311 dbSNP
rs916168587 2315 dbSNP
rs1009710316 2317 dbSNP
rs1057347942 2325 dbSNP
rs938857063 2333 dbSNP
rs1335778623 2338 dbSNP
rs893593712 2340 dbSNP
rs1293108772 2345 dbSNP
rs1259132278 2346 dbSNP
rs1486734025 2348 dbSNP
rs1311640341 2349 dbSNP
rs555228409 2351 dbSNP
rs1255469106 2352 dbSNP
rs1053881400 2358 dbSNP
rs1342570385 2363 dbSNP
rs544699955 2365 dbSNP
rs1393768624 2374 dbSNP
rs1314452150 2382 dbSNP
rs977208049 2387 dbSNP
rs1346529172 2391 dbSNP
rs968437734 2392 dbSNP
rs1387321446 2396 dbSNP
rs575612818 2409 dbSNP
rs905379456 2410 dbSNP
rs1295608579 2411 dbSNP
rs1458801683 2424 dbSNP
rs1227801523 2428 dbSNP
rs1305140504 2431 dbSNP
rs1046604079 2438 dbSNP
rs1318952684 2442 dbSNP
rs1216306955 2443 dbSNP
rs975087326 2449 dbSNP
rs1164040876 2453 dbSNP
rs181045406 2457 dbSNP
rs766087944 2457 dbSNP
rs538617563 2458 dbSNP
rs188545529 2462 dbSNP
rs1179377733 2466 dbSNP
rs975496560 2471 dbSNP
rs1419275768 2488 dbSNP
rs951321924 2493 dbSNP
rs1191331478 2508 dbSNP
rs775200021 2510 dbSNP
rs144272106 2511 dbSNP
rs1376525897 2520 dbSNP
rs899270401 2523 dbSNP
rs553347632 2529 dbSNP
rs954671196 2541 dbSNP
rs1021023735 2547 dbSNP
rs1224515249 2553 dbSNP
rs1300804086 2554 dbSNP
rs1210900995 2575 dbSNP
rs771658235 2577 dbSNP
rs533865063 2579 dbSNP
rs1249940517 2583 dbSNP
rs758967608 2595 dbSNP
rs1234083086 2596 dbSNP
rs1480650095 2603 dbSNP
rs58368380 2605 dbSNP
rs1363983237 2606 dbSNP
rs1016280847 2609 dbSNP
rs1250688440 2617 dbSNP
rs1297768012 2618 dbSNP
rs1452970251 2644 dbSNP
rs745357804 2646 dbSNP
rs1396271484 2647 dbSNP
rs1429648789 2650 dbSNP
rs1168481741 2654 dbSNP
rs576648794 2666 dbSNP
rs115302390 2667 dbSNP
rs1442963361 2669 dbSNP
rs894443441 2671 dbSNP
rs1369042675 2678 dbSNP
rs1057513272 2681 dbSNP
rs1341413472 2698 dbSNP
rs1405831182 2702 dbSNP
rs905347011 2717 dbSNP
rs1274967136 2722 dbSNP
rs1307582016 2724 dbSNP
rs1392656214 2736 dbSNP
rs938944591 2738 dbSNP
rs1469524148 2740 dbSNP
rs1195949400 2742 dbSNP
rs1253990917 2747 dbSNP
rs1429399361 2748 dbSNP
rs1475270161 2751 dbSNP
rs547948591 2752 dbSNP
rs531424590 2755 dbSNP
rs887400936 2760 dbSNP
rs1047502715 2763 dbSNP
rs931290853 2765 dbSNP
rs750896604 2777 dbSNP
rs1326781049 2782 dbSNP
rs919932184 2782 dbSNP
rs1043419 2785 dbSNP
rs1271861468 2787 dbSNP
rs574184832 2796 dbSNP
rs914342105 2797 dbSNP
rs552258072 2798 dbSNP
rs867638883 2800 dbSNP
rs532001881 2802 dbSNP
rs757661445 2804 dbSNP
rs139552356 2808 dbSNP
rs369899444 2808 dbSNP
rs1267049479 2813 dbSNP
rs1230082477 2814 dbSNP
rs1446802518 2817 dbSNP
rs6669 2825 dbSNP
rs987148453 2827 dbSNP
rs1476013186 2833 dbSNP
rs763812356 2834 dbSNP
rs1273688180 2837 dbSNP
rs1415805986 2839 dbSNP
rs954786553 2845 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 23369.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

miRNA-target interactions (Provided by authors)
ID Duplex structure Position
1 
miRNA  3' cuuuagAGAUGUCUUCGGGGUAu 5'
                |||||| |  |||||| 
Target 5' gguaggUCUACA-A--CCCCAUa 3'
 		4 - 23
Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000338086.5 | 3UTR | UCUGGUAGGUCUACAACCCCAUAGCACAACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
32 hsa-miR-3675-5p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT366903 NONO non-POU domain containing octamer binding 2 2
MIRT453894 DUSP18 dual specificity phosphatase 18 2 2
MIRT461725 ZNF426 zinc finger protein 426 2 2
MIRT464694 UBE2V1 ubiquitin conjugating enzyme E2 V1 2 2
MIRT465957 TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 2 2
MIRT466038 TMEM189 transmembrane protein 189 2 2
MIRT471546 PAX5 paired box 5 2 2
MIRT472813 MTMR12 myotubularin related protein 12 2 2
MIRT474099 LMBR1L limb development membrane protein 1 like 2 2
MIRT480205 CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 2 2
MIRT488268 HSP90AB1 heat shock protein 90 alpha family class B member 1 2 8
MIRT491222 MRPL34 mitochondrial ribosomal protein L34 2 2
MIRT494768 AP1G1 adaptor related protein complex 1 gamma 1 subunit 2 2
MIRT497228 MORC2 MORC family CW-type zinc finger 2 2 2
MIRT501676 PFN1 profilin 1 2 6
MIRT511831 H2AFX H2A histone family member X 2 4
MIRT513880 HNRNPUL1 heterogeneous nuclear ribonucleoprotein U like 1 2 4
MIRT519402 DNASE2 deoxyribonuclease 2, lysosomal 2 4
MIRT522627 MAP7D1 MAP7 domain containing 1 2 4
MIRT546998 PPP2CA protein phosphatase 2 catalytic subunit alpha 2 2
MIRT555119 PUM2 pumilio RNA binding family member 2 2 2
MIRT560380 TIMM8A translocase of inner mitochondrial membrane 8A 2 2
MIRT572188 CDADC1 cytidine and dCMP deaminase domain containing 1 2 2
MIRT634822 ASB6 ankyrin repeat and SOCS box containing 6 2 2
MIRT641149 DNMBP dynamin binding protein 2 2
MIRT647389 ZNF616 zinc finger protein 616 2 2
MIRT670851 SFT2D2 SFT2 domain containing 2 2 2
MIRT698600 TEX261 testis expressed 261 2 2
MIRT698691 TBPL1 TATA-box binding protein like 1 2 2
MIRT708725 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT718340 SYNDIG1L synapse differentiation inducing 1 like 2 2
MIRT725514 FBXO46 F-box protein 46 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-3675 Doxorubicin 31703 NSC123127 approved sensitive High Triple-Negative Breast Cancer cell line (MDA-MB-231, MDA-MB-468)
hsa-miR-3675-5p Cisplatin 5460033 NSC119875 approved resistant cell line (MGC-803)
hsa-miR-3675-5p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)

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