pre-miRNA Information
pre-miRNA hsa-mir-2115   
Genomic Coordinates chr3: 48316360 - 48316459
Description Homo sapiens miR-2115 stem-loop
Comment None
RNA Secondary Structure

Mature miRNA Information
Mature miRNA hsa-miR-2115-3p
Sequence 58| CAUCAGAAUUCAUGGAGGCUAG |79
Evidence Experimental
Experiments 454
DRVs in miRNA
Mutant ID Mutant Position Mutant Source
COSN31490809 22 COSMIC
COSN31579735 22 COSMIC
SNPs in miRNA
Mutant ID Mutant Position Mutant Source
rs543123304 18 dbSNP
rs1450988157 21 dbSNP
Putative Targets

miRNA Expression profile
miRNAs in Extracellular Vesicles
Circulating MicroRNA Expression Profiling
Gene Information
Gene Symbol LIPA   
Synonyms CESD, LAL
Description lipase A, lysosomal acid type
Transcript NM_000235   
Other Transcripts NM_001127605   
Expression
Putative miRNA Targets on LIPA
3'UTR of LIPA
(miRNA target sites are highlighted)
>LIPA|NM_000235|3'UTR
   1 AAGCTGGACTTGAGCTGTGTACCACCAAGTCAATGATTATGTCATGTGAAAATGTGTTTGCTTCATTTCTGTAAAACACT
  81 TGTTTTTCTTTCCCAGGTCTTTTGTTTTTTTATATCCAAGAAAATGATAACTTTGAAGATGCCCAGTTCACTCTAGTTTC
 161 AATTAGAAACATACTAGCTATTTTTTCTTTAATTAGGGCTGGAATAGGAAGCCAGTGTCTCAACCATAGTATTGTCTCTT
 241 TAAGTCTTTTAAATATCACTGATGTGTAAAAAGGTCATTATATCCATTCTGTTTTTAAAATTTAAAATATATTGACTTTT
 321 TGCCCTTCATAGGACAAAGTAATATATGTGTTGGAATTTTAAAATTGTGTTGTCATTGGTAAATCTGTCACTGACTTAAG
 401 CGAGGTATAAAAGTACGCAGTTTTCATGTCCTTGCCTTAAAGAGCTCTCTAGTCTAACGGTCTTGTAGTTAGAGATCTAA
 481 ATGACATTTTATCATGTTTTCCTGCAGCAGGTGCATAGTCAAATCCAGAAATATCACAGCTGTGCCAGTAATAAGGATGC
 561 TAACAATTAATTTTATCAAACCTAACTGTGACAGCTGTGATTTGACACGTTTTAATTGCTCAGGTTAAATGAAATAGTTT
 641 TCCGGCGTCTTCAAAAACAAATTGCACTGATAAAACAAAAACAAAAGTATGTTTTAAATGCTTTGAAGACTGATACACTC
 721 AACCATCTATATTCATGAGCTCTCAATTTCATGGCAGGCCATAGTTCTACTTATCTGAGAAGCAAATCCCTGTGGAGACT
 801 ATACCACTATTTTTTCTGAGATTAATGTACTCTTGGAGCCCGCTACTGTCGTTATTGATCACATCTGTGTGAAGCCAAAG
 881 CCCCGTGGTTGCCCATGAGAAGTGTCCTTGTTCATTTTCACCCAAATGAAGTGTGAACGTGATGTTTTCGGATGCAAACT
 961 CAGCTCAGGGATTCATTTTGTGTCTTAGTTTTATATGCATCCTTATTTTTAATACACCTGCTTCACGTCCCTATGTTGGG
1041 AAGTCCATATTTGTCTGCTTTTCTTGCAGCATCATTTCCTTACAATACTGTCCGGTGGACAAAATGACAATTGATATGTT
1121 TTTCTGATATAATTACTTTAGCTGCACTAACAGTACAATGCTTGTTAATGGTTAATATAGGCAGGGCGAATACTACTTTG
1201 TAACTTTTAAAGTCTTAAACTTTTCAATAAAATTGAGTGAGACTTATAGGCCCAAAGAAAAAAAAAAAAAA
Target sites Provided by authors   Predicted by miRanda    DRVs    SNPs    DRVs & SNPs
miRNA-target interactions
(Predicted by miRanda)
ID Duplex structure Position Score MFE
1
miRNA  3' gaucggagGUAC-UUAAGACUAc 5'
                  :|||   ||||||| 
Target 5' acaattgaTATGTTTTTCTGATa 3'
1107 - 1129 142.00 -8.60
2
miRNA  3' gaucGGAGGUACUUAAGACUac 5'
              || |:||   ||||||  
Target 5' tataCCACTATTTTTTCTGAga 3'
800 - 821 134.00 -11.30
3
miRNA  3' gaUCGG--AGGUACUUAAGACUAc 5'
            :|:|  | :||  |||||| | 
Target 5' aaGGTCATTATATCCATTCTGTTt 3'
271 - 294 122.00 -7.72
DRVs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
301571 151 ClinVar
878206 184 ClinVar
301570 330 ClinVar
878205 383 ClinVar
301569 385 ClinVar
877170 458 ClinVar
301568 491 ClinVar
877169 494 ClinVar
301567 508 ClinVar
301566 534 ClinVar
301565 544 ClinVar
879960 557 ClinVar
301564 573 ClinVar
879959 608 ClinVar
301563 618 ClinVar
301562 643 ClinVar
301561 744 ClinVar
301560 804 ClinVar
301558 841 ClinVar
301559 841 ClinVar
878138 842 ClinVar
301557 858 ClinVar
301556 876 ClinVar
301555 909 ClinVar
877103 921 ClinVar
301554 939 ClinVar
301553 949 ClinVar
301552 991 ClinVar
301551 1045 ClinVar
301550 1091 ClinVar
301549 1093 ClinVar
879919 1147 ClinVar
301548 1187 ClinVar
301547 1205 ClinVar
COSN31495541 7 COSMIC
COSN23987268 61 COSMIC
COSN15661315 62 COSMIC
COSN31547217 83 COSMIC
COSN31525666 120 COSMIC
COSN20247621 153 COSMIC
COSN17274175 214 COSMIC
COSN22714937 269 COSMIC
COSN20425101 892 COSMIC
COSN10074828 926 COSMIC
COSN1505954 938 COSMIC
SNPs in gene 3'UTRs
Mutant ID Mutant Position Mutant Source
rs1166790145 5 dbSNP
rs764660398 7 dbSNP
rs1472873487 9 dbSNP
rs1250971646 13 dbSNP
rs1175478646 14 dbSNP
rs11203037 15 dbSNP
rs1481577679 17 dbSNP
rs200864335 19 dbSNP
rs776578147 24 dbSNP
rs1468170232 26 dbSNP
rs763823355 28 dbSNP
rs1235497307 31 dbSNP
rs760555955 32 dbSNP
rs1306747025 33 dbSNP
rs1041742748 34 dbSNP
rs559389767 41 dbSNP
rs1317617959 44 dbSNP
rs772483310 45 dbSNP
rs140195774 50 dbSNP
rs756115349 51 dbSNP
rs895644426 64 dbSNP
rs752738142 92 dbSNP
rs929188037 96 dbSNP
rs899053768 97 dbSNP
rs532158667 102 dbSNP
rs1194379303 104 dbSNP
rs1354490717 105 dbSNP
rs146148229 106 dbSNP
rs1282821431 109 dbSNP
rs1483368154 112 dbSNP
rs941320104 112 dbSNP
rs1184293256 122 dbSNP
rs376581093 124 dbSNP
rs1418292949 142 dbSNP
rs1187930321 143 dbSNP
rs1369897876 144 dbSNP
rs767578516 151 dbSNP
rs11538026 152 dbSNP
rs1162422529 153 dbSNP
rs1370614248 154 dbSNP
rs911233348 156 dbSNP
rs1296960937 162 dbSNP
rs1373167071 166 dbSNP
rs759623981 172 dbSNP
rs1397035433 179 dbSNP
rs543234301 180 dbSNP
rs1338962406 184 dbSNP
rs1245488940 187 dbSNP
rs774521310 194 dbSNP
rs1215959657 201 dbSNP
rs934133402 208 dbSNP
rs1344450079 211 dbSNP
rs1348763728 219 dbSNP
rs1249563198 231 dbSNP
rs1282737498 233 dbSNP
rs964286280 242 dbSNP
rs184624731 245 dbSNP
rs1480262783 249 dbSNP
rs1200891527 253 dbSNP
rs1232282739 254 dbSNP
rs1257973076 260 dbSNP
rs1442451280 266 dbSNP
rs911086208 268 dbSNP
rs1370546370 275 dbSNP
rs1390330764 276 dbSNP
rs1273976339 277 dbSNP
rs1450806296 279 dbSNP
rs1167687220 283 dbSNP
rs1354538346 311 dbSNP
rs1466973760 322 dbSNP
rs922757165 323 dbSNP
rs1404387772 326 dbSNP
rs1452327228 326 dbSNP
rs1298618084 328 dbSNP
rs117967877 330 dbSNP
rs1212946207 342 dbSNP
rs955196322 344 dbSNP
rs1233855741 348 dbSNP
rs542997576 350 dbSNP
rs146813341 353 dbSNP
rs956220168 353 dbSNP
rs1316188624 367 dbSNP
rs1025407627 368 dbSNP
rs1184294961 369 dbSNP
rs1418131511 374 dbSNP
rs1418541734 378 dbSNP
rs763288984 385 dbSNP
rs572392638 401 dbSNP
rs970091927 402 dbSNP
rs773421175 404 dbSNP
rs1321633346 405 dbSNP
rs113254629 416 dbSNP
rs962388274 417 dbSNP
rs1014418525 425 dbSNP
rs1220979380 427 dbSNP
rs1285130057 444 dbSNP
rs1424070994 447 dbSNP
rs1016594717 451 dbSNP
rs1222741214 452 dbSNP
rs1006504114 458 dbSNP
rs368430299 459 dbSNP
rs1476622208 460 dbSNP
rs12255010 477 dbSNP
rs894713595 479 dbSNP
rs1026083070 485 dbSNP
rs115701525 491 dbSNP
rs1193662639 493 dbSNP
rs1003454769 494 dbSNP
rs1267455482 502 dbSNP
rs748642810 505 dbSNP
rs116332581 508 dbSNP
rs556769331 511 dbSNP
rs1158694441 513 dbSNP
rs1259635468 526 dbSNP
rs1208845100 531 dbSNP
rs142777525 534 dbSNP
rs1274026014 542 dbSNP
rs187747826 544 dbSNP
rs1054371867 546 dbSNP
rs942666524 557 dbSNP
rs911126486 563 dbSNP
rs369028997 564 dbSNP
rs1283138392 573 dbSNP
rs769179666 573 dbSNP
rs1224163966 574 dbSNP
rs555829287 577 dbSNP
rs1490343958 578 dbSNP
rs1183565982 580 dbSNP
rs918400264 594 dbSNP
rs1468930043 599 dbSNP
rs9664201 608 dbSNP
rs375722909 609 dbSNP
rs962443218 609 dbSNP
rs886047469 618 dbSNP
rs1016645625 633 dbSNP
rs565573256 635 dbSNP
rs1358198818 636 dbSNP
rs990891613 640 dbSNP
rs115320174 643 dbSNP
rs1035020554 645 dbSNP
rs114576393 646 dbSNP
rs571012707 647 dbSNP
rs1247688478 649 dbSNP
rs183051471 657 dbSNP
rs1358148915 662 dbSNP
rs1020391191 667 dbSNP
rs1205170650 677 dbSNP
rs1420689688 681 dbSNP
rs1436573817 697 dbSNP
rs1185859454 701 dbSNP
rs1204315720 705 dbSNP
rs1238388936 724 dbSNP
rs1446768668 725 dbSNP
rs1482994506 730 dbSNP
rs1384764772 732 dbSNP
rs1233650484 736 dbSNP
rs1450182059 738 dbSNP
rs41284116 744 dbSNP
rs893213490 751 dbSNP
rs1054500057 755 dbSNP
rs1052130903 774 dbSNP
rs531443999 779 dbSNP
rs192824659 782 dbSNP
rs1334290003 783 dbSNP
rs150851597 787 dbSNP
rs778531000 796 dbSNP
rs527671966 799 dbSNP
rs1053097328 801 dbSNP
rs1295111738 802 dbSNP
rs886047468 804 dbSNP
rs1377896784 809 dbSNP
rs926112502 815 dbSNP
rs1043253266 816 dbSNP
rs1242822574 822 dbSNP
rs933878703 826 dbSNP
rs1371388398 827 dbSNP
rs918454163 827 dbSNP
rs116074523 841 dbSNP
rs187138384 842 dbSNP
rs909636690 847 dbSNP
rs1470842410 850 dbSNP
rs866511916 851 dbSNP
rs990548888 855 dbSNP
rs886047467 858 dbSNP
rs1319827979 863 dbSNP
rs959661214 867 dbSNP
rs141445686 876 dbSNP
rs183167291 878 dbSNP
rs544783488 884 dbSNP
rs1034666029 885 dbSNP
rs971806929 886 dbSNP
rs1163469591 893 dbSNP
rs1446332984 895 dbSNP
rs574200134 899 dbSNP
rs1131706 909 dbSNP
rs971607818 910 dbSNP
rs1408722631 912 dbSNP
rs1016499335 919 dbSNP
rs1179037686 921 dbSNP
rs1207147276 926 dbSNP
rs190563011 932 dbSNP
rs1446505717 938 dbSNP
rs774820637 939 dbSNP
rs755914073 949 dbSNP
rs527378133 950 dbSNP
rs1481358167 956 dbSNP
rs1174057520 959 dbSNP
rs957495446 964 dbSNP
rs1428364104 970 dbSNP
rs1454085125 971 dbSNP
rs1274971805 976 dbSNP
rs752546242 983 dbSNP
rs886047466 991 dbSNP
rs901172492 996 dbSNP
rs1323638301 997 dbSNP
rs767523765 1010 dbSNP
rs1347981797 1014 dbSNP
rs567174182 1015 dbSNP
rs1403618219 1017 dbSNP
rs1283154288 1019 dbSNP
rs1351521913 1022 dbSNP
rs186524714 1026 dbSNP
rs1374158398 1027 dbSNP
rs1308141985 1033 dbSNP
rs1442081086 1034 dbSNP
rs561490465 1045 dbSNP
rs1294013672 1047 dbSNP
rs1324304078 1048 dbSNP
rs1457792462 1062 dbSNP
rs1197227529 1063 dbSNP
rs1268006450 1067 dbSNP
rs570998402 1070 dbSNP
rs867458194 1079 dbSNP
rs1183703871 1082 dbSNP
rs1361769370 1090 dbSNP
rs886047465 1091 dbSNP
rs13500 1093 dbSNP
rs1163721199 1094 dbSNP
rs1366923254 1096 dbSNP
rs998138385 1097 dbSNP
rs897073424 1100 dbSNP
rs1399081178 1105 dbSNP
rs148323117 1108 dbSNP
rs1194578959 1117 dbSNP
rs1043546131 1123 dbSNP
rs1305306961 1129 dbSNP
rs1335446955 1134 dbSNP
rs941180537 1138 dbSNP
rs1455750205 1141 dbSNP
rs1254587279 1144 dbSNP
rs766524456 1146 dbSNP
rs1245823235 1147 dbSNP
rs1317370659 1153 dbSNP
rs1357369610 1155 dbSNP
rs1189274277 1158 dbSNP
rs550302490 1164 dbSNP
rs1221768062 1177 dbSNP
rs1291020325 1177 dbSNP
rs1480914831 1178 dbSNP
rs78931290 1187 dbSNP
rs1248126308 1188 dbSNP
rs894644925 1192 dbSNP
rs1057386642 1193 dbSNP
rs1386636743 1194 dbSNP
rs938955264 1199 dbSNP
rs1162366340 1202 dbSNP
rs1055298744 1204 dbSNP
rs886047464 1205 dbSNP
rs1284856761 1209 dbSNP
rs1296902256 1214 dbSNP
rs1219632428 1217 dbSNP
rs1234475120 1219 dbSNP
rs773544003 1227 dbSNP
rs200603221 1243 dbSNP
rs113430289 1254 dbSNP
Experimental Support 1 for Functional miRNA-Target Interaction
miRNA:Target ----
Validation Method
Conditions HEK293
Disease 3988.0
Location of target site 3'UTR
Tools used in this research TargetScan , miRTarCLIP , Piranha
Original Description (Extracted from the article) ... "PAR-CLIP data was present in GSM714644. RNA binding protein: AGO2. Condition:completeT1 ...

- Kishore S; Jaskiewicz L; Burger L; Hausser et al., 2011, Nature methods.

Article - Kishore S; Jaskiewicz L; Burger L; Hausser et al.
- Nature methods, 2011
Cross-linking and immunoprecipitation (CLIP) is increasingly used to map transcriptome-wide binding sites of RNA-binding proteins. We developed a method for CLIP data analysis, and applied it to compare CLIP with photoactivatable ribonucleoside-enhanced CLIP (PAR-CLIP) and to uncover how differences in cross-linking and ribonuclease digestion affect the identified sites. We found only small differences in accuracies of these methods in identifying binding sites of HuR, which binds low-complexity sequences, and Argonaute 2, which has a complex binding specificity. We found that cross-link-induced mutations led to single-nucleotide resolution for both PAR-CLIP and CLIP. Our results confirm the expectation from original CLIP publications that RNA-binding proteins do not protect their binding sites sufficiently under the denaturing conditions used during the CLIP procedure, and we show that extensive digestion with sequence-specific RNases strongly biases the recovered binding sites. This bias can be substantially reduced by milder nuclease digestion conditions.
LinkOut: [PMID: 21572407]
CLIP-seq Support 1 for dataset GSM714644
Method / RBP PAR-CLIP / AGO2
Cell line / Condition HEK293 / completeT1, repA
Location of target site ENST00000336233.5 | 3UTR | AUAUAAUUACUUUAGCUGCACUAACAG
Tools used in this analysis TargetScan, miRTarCLIP, and Piranha
Article / Accession Series PMID: 21572407 / GSE28865
CLIP-seq Viewer Link
MiRNA-Target Expression Profile
Dataset Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
MiRNA-Target Expression Profile (TCGA)
Tumor Pearson Correlation P-value for Pearson Correlation Spearman Correlation P-value for Spearman Correlation Samples Chart
HNSC -0.486 0.04 -0.560 0.02 14 Click to see details
LUSC -0.443 0.05 -0.411 0.06 15 Click to see details
BRCA -0.227 0.11 -0.315 0.04 31 Click to see details
STAD -0.812 0.2 -0.500 0.33 3 Click to see details
BLCA 0.39 0.22 0.086 0.44 6 Click to see details
UCEC -0.61 0.29 -0.500 0.33 3 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
LIHC 0.178 0.41 0.200 0.4 4 Click to see details
80 hsa-miR-2115-3p Target Genes:
Functional analysis:
ID Target Description Validation methods
Strong evidence Less strong evidence
MIRT057089 DDIT4 DNA damage inducible transcript 4 2 2
MIRT071216 FCF1 FCF1, rRNA-processing protein 2 2
MIRT226901 RAD23B RAD23 homolog B, nucleotide excision repair protein 2 2
MIRT235961 BACH1 BTB domain and CNC homolog 1 2 2
MIRT294569 ZNF460 zinc finger protein 460 2 4
MIRT321046 RAC1 Rac family small GTPase 1 2 4
MIRT359666 NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit 2 8
MIRT366451 KLHL15 kelch like family member 15 2 2
MIRT405375 ZBTB18 zinc finger and BTB domain containing 18 2 2
MIRT441794 TCEAL5 transcription elongation factor A like 5 2 2
MIRT443295 TCEAL3 transcription elongation factor A like 3 2 2
MIRT455275 DDX39B DExD-box helicase 39B 2 2
MIRT458523 C5orf22 chromosome 5 open reading frame 22 2 2
MIRT464960 TWIST1 twist family bHLH transcription factor 1 2 2
MIRT466848 STX6 syntaxin 6 2 2
MIRT469252 RHOB ras homolog family member B 2 2
MIRT469825 RAB14 RAB14, member RAS oncogene family 2 4
MIRT470047 PTGFRN prostaglandin F2 receptor inhibitor 2 2
MIRT471420 PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 2 2
MIRT472024 NPM1 nucleophosmin 1 2 2
MIRT484156 CENPN centromere protein N 2 2
MIRT485490 HMGN2 high mobility group nucleosomal binding domain 2 2 2
MIRT490462 PROSER2 proline and serine rich 2 2 2
MIRT493069 MTCH1 mitochondrial carrier 1 2 2
MIRT493573 HSP90AA1 heat shock protein 90 alpha family class A member 1 2 8
MIRT494919 NDUFC2-KCTD14 NDUFC2-KCTD14 readthrough 2 2
MIRT500439 ZMAT3 zinc finger matrin-type 3 2 2
MIRT500931 SRPR SRP receptor alpha subunit 2 4
MIRT501551 POC1B-GALNT4 POC1B-GALNT4 readthrough 2 2
MIRT501809 NEURL1B neuralized E3 ubiquitin protein ligase 1B 2 2
MIRT502415 GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 2 2
MIRT506504 MSANTD4 Myb/SANT DNA binding domain containing 4 with coiled-coils 2 2
MIRT507861 CCNE2 cyclin E2 2 2
MIRT510511 YOD1 YOD1 deubiquitinase 2 6
MIRT516073 RAB42 RAB42, member RAS oncogene family 2 2
MIRT519030 KYNU kynureninase 2 6
MIRT521762 PPIL1 peptidylprolyl isomerase like 1 2 4
MIRT522898 KCNJ3 potassium voltage-gated channel subfamily J member 3 2 4
MIRT527370 MGARP mitochondria localized glutamic acid rich protein 2 2
MIRT530691 C8orf46 chromosome 8 open reading frame 46 2 2
MIRT530867 TRUB1 TruB pseudouridine synthase family member 1 2 2
MIRT531832 MTPAP mitochondrial poly(A) polymerase 2 4
MIRT533035 ZBTB5 zinc finger and BTB domain containing 5 2 2
MIRT533165 WIPF2 WAS/WASL interacting protein family member 2 2 2
MIRT533464 TRIM71 tripartite motif containing 71 2 2
MIRT534331 SHCBP1 SHC binding and spindle associated 1 2 2
MIRT539372 ADSS adenylosuccinate synthase 2 6
MIRT545951 ZBTB10 zinc finger and BTB domain containing 10 2 2
MIRT553283 TSR1 TSR1, ribosome maturation factor 2 2
MIRT553532 TMEM185B transmembrane protein 185B 2 4
MIRT556480 LIPA lipase A, lysosomal acid type 2 2
MIRT556975 HSPA4L heat shock protein family A (Hsp70) member 4 like 2 2
MIRT557697 GATA6 GATA binding protein 6 2 2
MIRT558901 CCDC58 coiled-coil domain containing 58 2 2
MIRT559224 BLMH bleomycin hydrolase 2 2
MIRT559827 SLPI secretory leukocyte peptidase inhibitor 2 2
MIRT563435 SLC3A2 solute carrier family 3 member 2 2 2
MIRT569270 PCDH11X protocadherin 11 X-linked 2 2
MIRT571386 JKAMP JNK1/MAPK8-associated membrane protein 2 2
MIRT572567 AFF1 AF4/FMR2 family member 1 2 2
MIRT610400 AR androgen receptor 2 2
MIRT611058 ZNF621 zinc finger protein 621 2 2
MIRT635118 TMEM233 transmembrane protein 233 2 2
MIRT641617 DEFB118 defensin beta 118 2 2
MIRT642146 CHORDC1 cysteine and histidine rich domain containing 1 2 2
MIRT647295 C8orf33 chromosome 8 open reading frame 33 2 2
MIRT648155 MPLKIP M-phase specific PLK1 interacting protein 2 2
MIRT652780 TENM3 teneurin transmembrane protein 3 2 2
MIRT657356 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 2 2
MIRT658718 ELN elastin 2 2
MIRT662441 RALGAPA1 Ral GTPase activating protein catalytic alpha subunit 1 2 2
MIRT665302 ZBTB38 zinc finger and BTB domain containing 38 2 2
MIRT699898 RUNX1 runt related transcription factor 1 2 2
MIRT700921 PDS5A PDS5 cohesin associated factor A 2 2
MIRT700992 PDE3A phosphodiesterase 3A 2 2
MIRT707397 DCAF4L1 DDB1 and CUL4 associated factor 4 like 1 2 2
MIRT711895 INSIG2 insulin induced gene 2 2 2
MIRT712072 XRCC5 X-ray repair cross complementing 5 2 2
MIRT716121 PTPLAD2 3-hydroxyacyl-CoA dehydratase 4 1 1
MIRT724470 SMAD2 SMAD family member 2 2 2
miRNA-Drug Resistance Associations
miRNA Drug Name CID NSC FDA Effect/Pattern Detection Method Level Phenotype Condition
hsa-mir-2115 Docetaxel+Cisplatin+5-Fluorouracil sensitive tissue (hypopharyngeal squamous cell carcinoma)
hsa-mir-2115 Decitabine 451668 approved sensitive tissue (esopheageal cancer)
hsa-miR-2115-3p Imatinib 5291 NSC743414 approved resistant High Chronic Myelogenous Leukemia cell line (K562)
hsa-miR-2115-3p Osimertinib 71496458 NSC779217 approved resistant cell line (PC9)
hsa-miR-2115-3p Gefitinib 123631 NSC715055 approved resistant cell line (HCC827)
hsa-miR-2115-3p Cisplatin 5460033 NSC119875 approved resistant cell line (A2780)
hsa-miR-2115-3p Cisplatin 5460033 NSC119875 approved sensitive cell line (A549)
hsa-miR-2115-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (1500 ng/ml)
hsa-miR-2115-3p Gemcitabine 60750 NSC613327 approved sensitive cell line (PANC-1) (100 ng/ml)

Error report submission